A Workable Solution for Reducing the Large Number of Vehicle and Pedestrian Accidents Occurring on a Yellow Light

Traffic intersections are incredibly dangerous for drivers and pedestrians. Statistics from both Canada and the U.S. show a high number of fatalities and serious injuries related to crashes at intersections. In Canada, during 2019, the National Collision Database shows that 28% of traffic fatalities and 42% of serious injuries occurred at intersections. Likewise, the U.S. National Highway Traffic Administration (NHTSA) found that about 40% of the estimated 5,811,000 accidents in the U.S. during the year studied were intersection-related crashes. In fact, a major survey by the car insurance industry found that nearly 85% of drivers could not identify the correct action to take when approaching a yellow traffic light at an intersection. One major reason for these accidents is the “yellow light dilemma,” the ambiguous situation where a driver should stop or proceed forward when unexpectedly faced with a yellow light. This situation is even further exacerbated by the tendency of aggressive drivers to inappropriately speed up on the yellow just to get through the traffic light. A survey of Canadian drivers conducted by the Traffic Injury Research Foundation found that 9% of drivers admitted to speeding up to get through a traffic light. Another reason for these accidents is the increased danger of making a left-hand turn on yellow. According to the National Highway Traffic Safety Association (NHTSA), left turns occur in approximately 22.2% of collisions—as opposed to just 1.2% for right turns. Moreover, a study by CNN found left turns are three times as likely to kill pedestrians than right turns. The reason left turns are so much more likely to cause an accident is because they take a driver against traffic and in the path of oncoming cars. Additionally, most of these left turns occur at the driver’s discretion—as opposed to the distressingly brief left-hand arrow at busy intersections. Drive Safe Now proposes a workable solution for reducing the number of accidents occurring during a yellow light at intersections. We believe this fairly simple solution will save lives, prevent injuries, reduce damage to public and private property, and decrease insurance costs.

Seismic vulnerability assessment of urban buildings and traffic networks using fuzzy ordered weighted average

Urban buildings and urban traffic network are considered as the vital arteries of cities which have particular effects especially after the crisis in the search and rescue operations. The aim of this study is to determine the vulnerability of urban areas especially, buildings and traffic networks using multicriteria geographic information systems and decisionmaking methods. As there are many effective criteria on the seismic vulnerability that they have uncertain and vague properties, the method of this paper is applying fuzzy ordered weighted average(OWA) to model the seismic vulnerability of urban buildings and traffic networks in the most optimistic and pessimistic states. The study area is district 6 of Tehran that is affected by the four major faults, and thus will be threatened by the earthquakes. The achieved results illustrated the vulnerability with different degrees of risk levels including very high, high, medium, low and very low. The results show that in the most optimistic case 14% and in the pessimistic case 1% of buildings tolerate in very low vulnerability. The vulnerability of urban street network also indicates that in the optimistic case 12% and in the pessimistic case at most 9% of the area are in appropriate condition and the North and NorthEast of the study area are more vulnerable than South of it.

Classified VPN Network Traffic Flow Using Time Related to Artificial Neural Network

VPNs are vital for safeguarding communication routes in the continually changing cybersecurity world.However,increasing network attack complexity and variety require increasingly advanced algorithms to recognize and categorizeVPNnetwork data.We present a novelVPNnetwork traffic flowclassificationmethod utilizing Artificial Neural Networks(ANN).This paper aims to provide a reliable system that can identify a virtual private network(VPN)traffic fromintrusion attempts,data exfiltration,and denial-of-service assaults.We compile a broad dataset of labeled VPN traffic flows from various apps and usage patterns.Next,we create an ANN architecture that can handle encrypted communication and distinguish benign from dangerous actions.To effectively process and categorize encrypted packets,the neural network model has input,hidden,and output layers.We use advanced feature extraction approaches to improve the ANN’s classification accuracy by leveraging network traffic’s statistical and behavioral properties.We also use cutting-edge optimizationmethods to optimize network characteristics and performance.The suggested ANN-based categorization method is extensively tested and analyzed.Results show the model effectively classifies VPN traffic types.We also show that our ANN-based technique outperforms other approaches in precision,recall,and F1-score with 98.79%accuracy.This study improves VPN security and protects against new cyberthreats.Classifying VPNtraffic flows effectively helps enterprises protect sensitive data,maintain network integrity,and respond quickly to security problems.This study advances network security and lays the groundwork for ANN-based cybersecurity solutions.

Cyber Resilience through Real-Time Threat Analysis in Information Security

This paper examines how cybersecurity is developing and how it relates to more conventional information security. Although information security and cyber security are sometimes used synonymously, this study contends that they are not the same. The concept of cyber security is explored, which goes beyond protecting information resources to include a wider variety of assets, including people [1]. Protecting information assets is the main goal of traditional information security, with consideration to the human element and how people fit into the security process. On the other hand, cyber security adds a new level of complexity, as people might unintentionally contribute to or become targets of cyberattacks. This aspect presents moral questions since it is becoming more widely accepted that society has a duty to protect weaker members of society, including children [1]. The study emphasizes how important cyber security is on a larger scale, with many countries creating plans and laws to counteract cyberattacks. Nevertheless, a lot of these sources frequently neglect to define the differences or the relationship between information security and cyber security [1]. The paper focus on differentiating between cybersecurity and information security on a larger scale. The study also highlights other areas of cybersecurity which includes defending people, social norms, and vital infrastructure from threats that arise from online in addition to information and technology protection. It contends that ethical issues and the human factor are becoming more and more important in protecting assets in the digital age, and that cyber security is a paradigm shift in this regard [1].

Neural Network-Powered License Plate Recognition System Design

The development of scientific inquiry and research has yielded numerous benefits in the realm of intelligent traffic control systems, particularly in the realm of automatic license plate recognition for vehicles. The design of license plate recognition algorithms has undergone digitalization through the utilization of neural networks. In contemporary times, there is a growing demand for vehicle surveillance due to the need for efficient vehicle processing and traffic management. The design, development, and implementation of a license plate recognition system hold significant social, economic, and academic importance. The study aims to present contemporary methodologies and empirical findings pertaining to automated license plate recognition. The primary focus of the automatic license plate recognition algorithm was on image extraction, character segmentation, and recognition. The task of character segmentation has been identified as the most challenging function based on my observations. The license plate recognition project that we designed demonstrated the effectiveness of this method across various observed conditions. Particularly in low-light environments, such as during periods of limited illumination or inclement weather characterized by precipitation. The method has been subjected to testing using a sample size of fifty images, resulting in a 100% accuracy rate. The findings of this study demonstrate the project’s ability to effectively determine the optimal outcomes of simulations.

Dynamic Shortest Path Algorithm in Stochastic Traffic Networks Using PSO Based on Fluid Neural Network

The shortest path planning issure is critical for dynamic traffic assignment and route guidance in intelligent transportation systems. In this paper, a Particle Swarm Optimization (PSO) algorithm with priority-based encoding scheme based on fluid neural network (FNN) to search for the shortest path in stochastic traffic networks is introduced. The proposed algorithm overcomes the weight coefficient symmetry restrictions of the traditional FNN and disadvantage of easily getting into a local optimum for PSO. Simulation experiments have been carried out on different traffic network topologies consisting of 15-65 nodes and the results showed that the proposed approach can find the optimal path and closer sub-optimal paths with good success ratio. At the same time, the algorithms greatly improve the convergence efficiency of fluid neuron network.

Intelligent and Predictive Vehicular Networks

Seeking shortest travel times through smart algorithms may not only optimize the travel times but also reduce carbon emissions, such as CO2, CO and Hydro-Carbons. It can also result in reduced driver frustrations and can increase passenger expectations of consistent travel times, which in turn points to benefits in overall planning of day schedules. Fuel consumption savings are another benefit from the same. However, attempts to elect the shortest path as an assumption of quick travel times, often work counter to the very objective intended and come with the risk of creating a “Braess Paradox” which is about congestion resulting when several drivers attempt to elect the same shortest route. The situation that arises has been referred to as the price of anarchy! We propose algorithms that find multiple shortest paths between an origin and a destination. It must be appreciated that these will not yield the exact number of Kilometers travelled, but favourable weights in terms of travel times so that a reasonable allowable time difference between the multiple shortest paths is attained when the same Origin and Destinations are considered and favourable responsive routes are determined as variables of traffic levels and time of day. These routes are selected on the paradigm of route balancing, re-routing algorithms and traffic light intelligence all coming together to result in optimized consistent travel times whose benefits are evenly spread to all motorist, unlike the Entropy balanced k shortest paths (EBkSP) method which favours some motorists on the basis of urgency. This paper proposes a Fully Balanced Multiple-Candidate shortest path (FBMkP) by which we model in SUMO to overcome the computational overhead of assigning priority differently to each travelling vehicle using intelligence at intersections and other points on the vehicular network. The FBMkP opens up traffic by fully balancing the whole network so as to benefit every motorist. Whereas the EBkSP reserves some routes for cars on high priority, our algorithm distributes the benefits of smart routing to all vehicles on the network and serves the road side units such as induction loops and detectors from having to remember the urgency of each vehicle. Instead, detectors and induction loops simply have to poll the destination of the vehicle and not any urgency factor. The minimal data being processed significantly reduce computational times and the benefits all vehicles. The multiple-candidate shortest paths selected on the basis of current traffic status on each possible route increase the efficiency. Routes are fewer than vehicles so possessing weights of routes is smarter than processing individual vehicle weights. This is a multi-objective function project where improving one factor such as travel times improves many more cost, social and environmental factors.

Cluster DetectionMethod of Endogenous Security Abnormal Attack Behavior in Air Traffic Control Network

In order to enhance the accuracy of Air Traffic Control(ATC)cybersecurity attack detection,in this paper,a new clustering detection method is designed for air traffic control network security attacks.The feature set for ATC cybersecurity attacks is constructed by setting the feature states,adding recursive features,and determining the feature criticality.The expected information gain and entropy of the feature data are computed to determine the information gain of the feature data and reduce the interference of similar feature data.An autoencoder is introduced into the AI(artificial intelligence)algorithm to encode and decode the characteristics of ATC network security attack behavior to reduce the dimensionality of the ATC network security attack behavior data.Based on the above processing,an unsupervised learning algorithm for clustering detection of ATC network security attacks is designed.First,determine the distance between the clustering clusters of ATC network security attack behavior characteristics,calculate the clustering threshold,and construct the initial clustering center.Then,the new average value of all feature objects in each cluster is recalculated as the new cluster center.Second,it traverses all objects in a cluster of ATC network security attack behavior feature data.Finally,the cluster detection of ATC network security attack behavior is completed by the computation of objective functions.The experiment took three groups of experimental attack behavior data sets as the test object,and took the detection rate,false detection rate and recall rate as the test indicators,and selected three similar methods for comparative test.The experimental results show that the detection rate of this method is about 98%,the false positive rate is below 1%,and the recall rate is above 97%.Research shows that this method can improve the detection performance of security attacks in air traffic control network.

Application of Convolutional Neural Networks in Classification of GBM for Enhanced Prognosis

The lethal brain tumor “Glioblastoma” has the propensity to grow over time. To improve patient outcomes, it is essential to classify GBM accurately and promptly in order to provide a focused and individualized treatment plan. Despite this, deep learning methods, particularly Convolutional Neural Networks (CNNs), have demonstrated a high level of accuracy in a myriad of medical image analysis applications as a result of recent technical breakthroughs. The overall aim of the research is to investigate how CNNs can be used to classify GBMs using data from medical imaging, to improve prognosis precision and effectiveness. This research study will demonstrate a suggested methodology that makes use of the CNN architecture and is trained using a database of MRI pictures with this tumor. The constructed model will be assessed based on its overall performance. Extensive experiments and comparisons with conventional machine learning techniques and existing classification methods will also be made. It will be crucial to emphasize the possibility of early and accurate prediction in a clinical workflow because it can have a big impact on treatment planning and patient outcomes. The paramount objective is to not only address the classification challenge but also to outline a clear pathway towards enhancing prognosis precision and treatment effectiveness.

Semantic model and optimization of creative processes at mathematical knowledge formation

The aim of this work is mathematical education through the knowledge system and mathematical modeling. A net model of formation of mathematical knowledge as a deductive theory is suggested here. Within this model the formation of deductive theory is represented as the development of a certain informational space, the elements of which are structured in the form of the orientated semantic net. This net is properly metrized and characterized by a certain system of coverings. It allows injecting net optimization parameters, regulating qualitative aspects of knowledge system under consideration. To regulate the creative processes of the formation and realization of mathematical know- edge, stochastic model of formation deductive theory is suggested here in the form of branching Markovian process, which is realized in the corresponding informational space as a semantic net. According to this stochastic model we can get correct foundation of criterion of optimization creative processes that leads to “great main points” strategy (GMP-strategy) in the process of realization of the effective control in the research work in the sphere of mathematics and its applications.

Resource Efficient Hardware Implementation for Real-Time Traffic Sign Recognition

Traffic sign recognition (TSR, or Road Sign Recognition, RSR) is one of the Advanced Driver Assistance System (ADAS) devices in modern cars. To concern the most important issues, which are real-time and resource efficiency, we propose a high efficiency hardware implementation for TSR. We divide the TSR procedure into two stages, detection and recognition. In the detection stage, under the assumption that most German traffic signs have red or blue colors with circle, triangle or rectangle shapes, we use Normalized RGB color transform and Single-Pass Connected Component Labeling (CCL) to find the potential traffic signs efficiently. For Single-Pass CCL, our contribution is to eliminate the “merge-stack” operations by recording connected relations of region in the scan phase and updating the labels in the iterating phase. In the recognition stage, the Histogram of Oriented Gradient (HOG) is used to generate the descriptor of the signs, and we classify the signs with Support Vector Machine (SVM). In the HOG module, we analyze the required minimum bits under different recognition rate. The proposed method achieves 96.61% detection rate and 90.85% recognition rate while testing with the GTSDB dataset. Our hardware implementation reduces the storage of CCL and simplifies the HOG computation. Main CCL storage size is reduced by 20% comparing to the most advanced design under typical condition. By using TSMC 90 nm technology, the proposed design operates at 105 MHz clock rate and processes in 135 fps with the image size of 1360 × 800. The chip size is about 1 mm2 and the power consumption is close to 8 mW. Therefore, this work is resource efficient and achieves real-time requirement.

IDS-INT:Intrusion detection system using transformer-based transfer learning for imbalanced network traffic

A network intrusion detection system is critical for cyber security against llegitimate attacks.In terms of feature perspectives,network traffic may include a variety of elements such as attack reference,attack type,a subcategory of attack,host information,malicious scripts,etc.In terms of network perspectives,network traffic may contain an imbalanced number of harmful attacks when compared to normal traffic.It is challenging to identify a specific attack due to complex features and data imbalance issues.To address these issues,this paper proposes an Intrusion Detection System using transformer-based transfer learning for Imbalanced Network Traffic(IDS-INT).IDS-INT uses transformer-based transfer learning to learn feature interactions in both network feature representation and imbalanced data.First,detailed information about each type of attack is gathered from network interaction descriptions,which include network nodes,attack type,reference,host information,etc.Second,the transformer-based transfer learning approach is developed to learn detailed feature representation using their semantic anchors.Third,the Synthetic Minority Oversampling Technique(SMOTE)is implemented to balance abnormal traffic and detect minority attacks.Fourth,the Convolution Neural Network(CNN)model is designed to extract deep features from the balanced network traffic.Finally,the hybrid approach of the CNN-Long Short-Term Memory(CNN-LSTM)model is developed to detect different types of attacks from the deep features.Detailed experiments are conducted to test the proposed approach using three standard datasets,i.e.,UNsWNB15,CIC-IDS2017,and NSL-KDD.An explainable AI approach is implemented to interpret the proposed method and develop a trustable model.

Optimization Model Proposal for Traffic Differentiation in Wireless Sensor Networks

Wireless sensor networks(WSNs)are characterized by heterogeneous traffic types(audio,video,data)and diverse application traffic requirements.This paper introduces three traffic classes following the defined model of heterogeneous traffic differentiation in WSNs.The requirements for each class regarding sensitivity to QoS(Quality of Service)parameters,such as loss,delay,and jitter,are described.These classes encompass real-time and delay-tolerant traffic.Given that QoS evaluation is a multi-criteria decision-making problem,we employed the AHP(Analytical Hierarchy Process)method for multi-criteria optimization.As a result of this approach,we derived weight values for different traffic classes based on key QoS factors and requirements.These weights are assigned to individual traffic classes to determine transmission priority.This study provides a thorough comparative analysis of the proposed model against existing methods,demonstrating its superior performance across various traffic scenarios and its implications for future WSN applications.The results highlight the model’s adaptability and robustness in optimizing network resources under varying conditions,offering insights into practical deployments in real-world scenarios.Additionally,the paper includes an analysis of energy consumption,underscoring the trade-offs between QoS performance and energy efficiency.This study presents the development of a differentiated services model for heterogeneous traffic in wireless sensor networks,considering the appropriate QoS framework supported by experimental analyses.

Using Neural Networks to Predict Secondary Structure for Protein Folding

Protein Secondary Structure Prediction (PSSP) is considered as one of the major challenging tasks in bioinformatics, so many solutions have been proposed to solve that problem via trying to achieve more accurate prediction results. The goal of this paper is to develop and implement an intelligent based system to predict secondary structure of a protein from its primary amino acid sequence by using five models of Neural Network (NN). These models are Feed Forward Neural Network (FNN), Learning Vector Quantization (LVQ), Probabilistic Neural Network (PNN), Convolutional Neural Network (CNN), and CNN Fine Tuning for PSSP. To evaluate our approaches two datasets have been used. The first one contains 114 protein samples, and the second one contains 1845 protein samples.

Structural and functional connectivity of the whole brain and subnetworks in individuals with mild traumatic brain injury:predictors of patient prognosis

Patients with mild traumatic brain injury have a diverse clinical presentation,and the underlying pathophysiology remains poorly understood.Magnetic resonance imaging is a non-invasive technique that has been widely utilized to investigate neuro biological markers after mild traumatic brain injury.This approach has emerged as a promising tool for investigating the pathogenesis of mild traumatic brain injury.G raph theory is a quantitative method of analyzing complex networks that has been widely used to study changes in brain structure and function.However,most previous mild traumatic brain injury studies using graph theory have focused on specific populations,with limited exploration of simultaneous abnormalities in structural and functional connectivity.Given that mild traumatic brain injury is the most common type of traumatic brain injury encounte red in clinical practice,further investigation of the patient characteristics and evolution of structural and functional connectivity is critical.In the present study,we explored whether abnormal structural and functional connectivity in the acute phase could serve as indicators of longitudinal changes in imaging data and cognitive function in patients with mild traumatic brain injury.In this longitudinal study,we enrolled 46 patients with mild traumatic brain injury who were assessed within 2 wee ks of injury,as well as 36 healthy controls.Resting-state functional magnetic resonance imaging and diffusion-weighted imaging data were acquired for graph theoretical network analysis.In the acute phase,patients with mild traumatic brain injury demonstrated reduced structural connectivity in the dorsal attention network.More than 3 months of followup data revealed signs of recovery in structural and functional connectivity,as well as cognitive function,in 22 out of the 46 patients.Furthermore,better cognitive function was associated with more efficient networks.Finally,our data indicated that small-worldness in the acute stage could serve as a predictor of longitudinal changes in connectivity in patients with mild traumatic brain injury.These findings highlight the importance of integrating structural and functional connectivity in unde rstanding the occurrence and evolution of mild traumatic brain injury.Additionally,exploratory analysis based on subnetworks could serve a predictive function in the prognosis of patients with mild traumatic brain injury.

Applying an Improved Dung Beetle Optimizer Algorithm to Network Traffic Identification

Network traffic identification is critical for maintaining network security and further meeting various demands of network applications.However,network traffic data typically possesses high dimensionality and complexity,leading to practical problems in traffic identification data analytics.Since the original Dung Beetle Optimizer(DBO)algorithm,Grey Wolf Optimization(GWO)algorithm,Whale Optimization Algorithm(WOA),and Particle Swarm Optimization(PSO)algorithm have the shortcomings of slow convergence and easily fall into the local optimal solution,an Improved Dung Beetle Optimizer(IDBO)algorithm is proposed for network traffic identification.Firstly,the Sobol sequence is utilized to initialize the dung beetle population,laying the foundation for finding the global optimal solution.Next,an integration of levy flight and golden sine strategy is suggested to give dung beetles a greater probability of exploring unvisited areas,escaping from the local optimal solution,and converging more effectively towards a global optimal solution.Finally,an adaptive weight factor is utilized to enhance the search capabilities of the original DBO algorithm and accelerate convergence.With the improvements above,the proposed IDBO algorithm is then applied to traffic identification data analytics and feature selection,as so to find the optimal subset for K-Nearest Neighbor(KNN)classification.The simulation experiments use the CICIDS2017 dataset to verify the effectiveness of the proposed IDBO algorithm and compare it with the original DBO,GWO,WOA,and PSO algorithms.The experimental results show that,compared with other algorithms,the accuracy and recall are improved by 1.53%and 0.88%in binary classification,and the Distributed Denial of Service(DDoS)class identification is the most effective in multi-classification,with an improvement of 5.80%and 0.33%for accuracy and recall,respectively.Therefore,the proposed IDBO algorithm is effective in increasing the efficiency of traffic identification and solving the problem of the original DBO algorithm that converges slowly and falls into the local optimal solution when dealing with high-dimensional data analytics and feature selection for network traffic identification.

A Discrete-Time Traffic and Topology Adaptive Routing Algorithm for LEO Satellite Networks

“Minimizing path delay” is one of the challenges in low Earth orbit (LEO) satellite network routing algo-rithms. Many authors focus on propagation delays with the distance vector but ignore the status information and processing delays of inter-satellite links. For this purpose, a new discrete-time traffic and topology adap-tive routing (DT-TTAR) algorithm is proposed in this paper. This routing algorithm incorporates both inher-ent dynamics of network topology and variations of traffic load in inter-satellite links. The next hop decision is made by the adaptive link cost metric, depending on arrival rates, time slots and locations of source-destination pairs. Through comprehensive analysis, we derive computation formulas of the main per-formance indexes. Meanwhile, the performances are evaluated through a set of simulations, and compared with other static and adaptive routing mechanisms as a reference. The results show that the proposed DT-TTAR algorithm has better performance of end-to-end delay than other algorithms, especially in high traffic areas.

DNBP-CCA:A Novel Approach to Enhancing Heterogeneous Data Traffic and Reliable Data Transmission for Body Area Network

The increased adoption of Internet of Medical Things (IoMT) technologies has resulted in the widespread use ofBody Area Networks (BANs) in medical and non-medical domains. However, the performance of IEEE 802.15.4-based BANs is impacted by challenges related to heterogeneous data traffic requirements among nodes, includingcontention during finite backoff periods, association delays, and traffic channel access through clear channelassessment (CCA) algorithms. These challenges lead to increased packet collisions, queuing delays, retransmissions,and the neglect of critical traffic, thereby hindering performance indicators such as throughput, packet deliveryratio, packet drop rate, and packet delay. Therefore, we propose Dynamic Next Backoff Period and Clear ChannelAssessment (DNBP-CCA) schemes to address these issues. The DNBP-CCA schemes leverage a combination ofthe Dynamic Next Backoff Period (DNBP) scheme and the Dynamic Next Clear Channel Assessment (DNCCA)scheme. The DNBP scheme employs a fuzzy Takagi, Sugeno, and Kang (TSK) model’s inference system toquantitatively analyze backoff exponent, channel clearance, collision ratio, and data rate as input parameters. Onthe other hand, the DNCCA scheme dynamically adapts the CCA process based on requested data transmission tothe coordinator, considering input parameters such as buffer status ratio and acknowledgement ratio. As a result,simulations demonstrate that our proposed schemes are better than some existing representative approaches andenhance data transmission, reduce node collisions, improve average throughput, and packet delivery ratio, anddecrease average packet drop rate and packet delay.

Screening biomarkers for spinal cord injury using weighted gene co-expression network analysis and machine learning

Immune changes and inflammatory responses have been identified as central events in the pathological process of spinal co rd injury.They can greatly affect nerve regeneration and functional recovery.However,there is still limited understanding of the peripheral immune inflammato ry response in spinal cord inju ry.In this study.we obtained microRNA expression profiles from the peripheral blood of patients with spinal co rd injury using high-throughput sequencing.We also obtained the mRNA expression profile of spinal cord injury patients from the Gene Expression Omnibus(GEO)database(GSE151371).We identified 54 differentially expressed microRNAs and 1656 diffe rentially expressed genes using bioinformatics approaches.Functional enrichment analysis revealed that various common immune and inflammation-related signaling pathways,such as neutrophil extracellular trap formation pathway,T cell receptor signaling pathway,and nuclear factor-κB signal pathway,we re abnormally activated or inhibited in spinal cord inju ry patient samples.We applied an integrated strategy that combines weighted gene co-expression network analysis,LASSO logistic regression,and SVM-RFE algorithm and identified three biomarke rs associated with spinal cord injury:ANO10,BST1,and ZFP36L2.We verified the expression levels and diagnostic perfo rmance of these three genes in the original training dataset and clinical samples through the receiver operating characteristic curve.Quantitative polymerase chain reaction results showed that ANO20 and BST1 mRNA levels were increased and ZFP36L2 mRNA was decreased in the peripheral blood of spinal cord injury patients.We also constructed a small RNA-mRNA interaction network using Cytoscape.Additionally,we evaluated the proportion of 22 types of immune cells in the peripheral blood of spinal co rd injury patients using the CIBERSORT tool.The proportions of naive B cells,plasma cells,monocytes,and neutrophils were increased while the proportions of memory B cells,CD8^(+)T cells,resting natural killer cells,resting dendritic cells,and eosinophils were markedly decreased in spinal cord injury patients increased compared with healthy subjects,and ANO10,BST1 and ZFP26L2we re closely related to the proportion of certain immune cell types.The findings from this study provide new directions for the development of treatment strategies related to immune inflammation in spinal co rd inju ry and suggest that ANO10,BST2,and ZFP36L2 are potential biomarkers for spinal cord injury.The study was registe red in the Chinese Clinical Trial Registry(registration No.ChiCTR2200066985,December 12,2022).

Distributed Optimal Control for Traffic Networks with Fog Computing

This paper presents a distributed optimization strategy for large-scale traffic network based on fog computing. Different from the traditional cloud-based centralized optimization strategy, the fog-based distributed optimization strategy distributes its computing tasks to individual sub-processors, thus significantly reducing computation time. A traffic model is built and a series of communication rules between subsystems are set to ensure that the entire transportation network can be globally optimized while the subsystem is achieving its local optimization. Finally, this paper numerically simulates the operation of the traffic network by mixed-Integer programming, also, compares the advantages and disadvantages of the two optimization strategies.