<div style="text-align:justify;"> Based on the detailed interpretation of high-accuracy 3D seismic data, the characteristics of regional unconformities, fracture systems, sedimentary filling and paleo-...<div style="text-align:justify;"> Based on the detailed interpretation of high-accuracy 3D seismic data, the characteristics of regional unconformities, fracture systems, sedimentary filling and paleo-stress field in Zhu 1 depression were comprehensively analyzed. The results showed that 2nd episode of Zhu-Qiong movement was an important tectonic transformation that occurred during rifting, basin structure patterns above and below the regional angular unconformity caused by 2nd episode had distinct differences. The orientations of those basin-controlling faults changed from NE, NEE to EW, NWW, which indicated that the paleo-stress field veered from NNW extension clockwise to sub-NS extension and basin structures patterns transformed from NE, NEE strong rifting to sub-EW, NWW weak rifting. The depocenter showed seesaw-like migration from S to N. And the sedimentary systems transformed from semi-deep-deep lacustrine facies to braided river delta facies developed in shore-shallow lacustrine. Combined with its tectonic recombination of periphery plates that period, the mechanism of above tectonic transformation had direct correspondence to the readjustment of the Indian plate and the Pacific plate. The southward subduction of the pro-to-south China Sea is the direct cause of this tectonic transformation. </div>展开更多
NGLY1 Deficiency is an autosomal recessive congenital disorder that has been identified in less than 100 individuals. Most individuals with NGLY1 Deficiency display hyperkinetic movement disorders, including choreifor...NGLY1 Deficiency is an autosomal recessive congenital disorder that has been identified in less than 100 individuals. Most individuals with NGLY1 Deficiency display hyperkinetic movement disorders, including choreiform, athetoid, dystonic myoclonic, dyskinetic, and dysmetric movements. Developing a consistent and concise consensus on the classification and evaluation of tremors is essential to forward the research and treatment of tremors. It has also been reported that some individuals with NGLY1 Deficiency demonstrate tremor, but such tremor has never been formally investigated. The primary objective of this study is to determine if an individual with NGLY1 Deficiency demonstrates an identifiable tremor during a series of arm movements and, if so, describe the frequency and power characteristics of that tremor. Arm movement kinematics were obtained using a 16-camera Vicon system, and time series trajectory waveforms for three planes of a marker placed on the hand were developed. Custom MATLAB scripts were utilized to compute Fast Fourier Transformations of the data within the identified waveform segments. A mean frequency of 2.30 Hz (SD = 1.05) with a mean power of 5.02 |P1(f)| (SD = 4.63) suggests that our participant’s kinematic data did display a persistent tremor in both hands across all tasks and movement planes. Analyses of the reaching hand and the non-reaching hand suggest the participant displayed an action tremor in both postural and intention (kinetic) tremors. Future directions should include assessing additional individuals with NGLY1 Deficiency to determine if the tremor is a distinguishable disorder behavior. Additionally, evaluating other anatomical sites, such as the elbow, head, and lower limbs, would provide further insights into the characteristics of this tremor.展开更多
文摘<div style="text-align:justify;"> Based on the detailed interpretation of high-accuracy 3D seismic data, the characteristics of regional unconformities, fracture systems, sedimentary filling and paleo-stress field in Zhu 1 depression were comprehensively analyzed. The results showed that 2nd episode of Zhu-Qiong movement was an important tectonic transformation that occurred during rifting, basin structure patterns above and below the regional angular unconformity caused by 2nd episode had distinct differences. The orientations of those basin-controlling faults changed from NE, NEE to EW, NWW, which indicated that the paleo-stress field veered from NNW extension clockwise to sub-NS extension and basin structures patterns transformed from NE, NEE strong rifting to sub-EW, NWW weak rifting. The depocenter showed seesaw-like migration from S to N. And the sedimentary systems transformed from semi-deep-deep lacustrine facies to braided river delta facies developed in shore-shallow lacustrine. Combined with its tectonic recombination of periphery plates that period, the mechanism of above tectonic transformation had direct correspondence to the readjustment of the Indian plate and the Pacific plate. The southward subduction of the pro-to-south China Sea is the direct cause of this tectonic transformation. </div>
文摘NGLY1 Deficiency is an autosomal recessive congenital disorder that has been identified in less than 100 individuals. Most individuals with NGLY1 Deficiency display hyperkinetic movement disorders, including choreiform, athetoid, dystonic myoclonic, dyskinetic, and dysmetric movements. Developing a consistent and concise consensus on the classification and evaluation of tremors is essential to forward the research and treatment of tremors. It has also been reported that some individuals with NGLY1 Deficiency demonstrate tremor, but such tremor has never been formally investigated. The primary objective of this study is to determine if an individual with NGLY1 Deficiency demonstrates an identifiable tremor during a series of arm movements and, if so, describe the frequency and power characteristics of that tremor. Arm movement kinematics were obtained using a 16-camera Vicon system, and time series trajectory waveforms for three planes of a marker placed on the hand were developed. Custom MATLAB scripts were utilized to compute Fast Fourier Transformations of the data within the identified waveform segments. A mean frequency of 2.30 Hz (SD = 1.05) with a mean power of 5.02 |P1(f)| (SD = 4.63) suggests that our participant’s kinematic data did display a persistent tremor in both hands across all tasks and movement planes. Analyses of the reaching hand and the non-reaching hand suggest the participant displayed an action tremor in both postural and intention (kinetic) tremors. Future directions should include assessing additional individuals with NGLY1 Deficiency to determine if the tremor is a distinguishable disorder behavior. Additionally, evaluating other anatomical sites, such as the elbow, head, and lower limbs, would provide further insights into the characteristics of this tremor.
