Brain-derived neurotrophic factor(BDNF) attracts increasing attention from both research and clinical fields because of its important functions in the central nervous system. An adequate amount of BDNF is critical to ...Brain-derived neurotrophic factor(BDNF) attracts increasing attention from both research and clinical fields because of its important functions in the central nervous system. An adequate amount of BDNF is critical to develop and maintain normal neuronal circuits in the brain. Given that loss of BDNF function has beenreported in the brains of patients with neurodegenerative or psychiatric diseases, understanding basic properties of BDNF and associated intracellular processes is imperative. In this review, we revisit the gene structure, transcription, translation, transport and secretion mechanisms of BDNF. We also introduce implications of BDNF in several brain-related diseases including Alzheimer's disease, Huntington's disease, depression and schizophrenia.展开更多
After China＇s entry into WTO, our industries will be confronted with fiercer competition. How to strengthen their international competitiveness to seek for survival and development has become a very urgent problem. T...After China＇s entry into WTO, our industries will be confronted with fiercer competition. How to strengthen their international competitiveness to seek for survival and development has become a very urgent problem. This paper first simply discusses the meaning and theo^es of industrial international competitiveness, then chooses proper indexes according to some principles, explains the factor analysis method of industrial international competitiveness, and finally makes empirical analysis on China air transport industry.展开更多
Diffusion has been systematically described as the main mechanism of chloride transport in reinforced concrete（RC） structure, especially when the concrete is in a saturated state. However, the single mechanism of di...Diffusion has been systematically described as the main mechanism of chloride transport in reinforced concrete（RC） structure, especially when the concrete is in a saturated state. However, the single mechanism of diffusion is not able to describe the actual chloride ingress in the nonsaturated concrete. Instead, it is dominated by the interaction of diffusion and convection. With the synergetic effects of various factors taken into account, this study aimed to modify and develop an analytical convection- diffusion coupling model for chloride transport in nonsaturated concrete. The model was verified by simulation of laboratory tests and field measurement. The results of comparison study demonstrate that the analytical model developed in this study is efficient and accurate in predicting the chloride profiles in the nonsaturated concrete.展开更多
In this experimental study we coupled nerve growth factor (NGF) with notatin by dicyclohexylcarbodiimide to label NGF and observed the effects of NGF on axonal retrograde transport after axonal injury of motoneurons w...In this experimental study we coupled nerve growth factor (NGF) with notatin by dicyclohexylcarbodiimide to label NGF and observed the effects of NGF on axonal retrograde transport after axonal injury of motoneurons with the aid of notatin chemiluminescence system. The results showed that NGF could be transported through axon not only to sensory neurons in dorsal root ganglia but also to motoneurons in spinal cord ventral horn.展开更多
The transportation industry is the basic industry of national economic development. At the same time, it is the only industry in China that has continuously increased CO2 emissions, and the high energy consumption pro...The transportation industry is the basic industry of national economic development. At the same time, it is the only industry in China that has continuously increased CO2 emissions, and the high energy consumption problems have not been solved. Henan province, as a major energy consumption province, it is urgent to improve the supply quality of transportation industry. The paper uses the IPCC calculation method for carbon emission to calculate the CO2 emissions of transportation industry in Henan province from 2004 to 2014. Then, this paper uses the LMDI method to decompose the CO2 emission in the transportation industry and give the proposal to reduce the CO2 emission according to the CO2 emission drivers.展开更多
基金Supported by The Health and Labor Sciences Research Grants(Comprehensive Research on Disability,Health,and Welfare H21-kokoro-002)(H.K.)the Core Research for Evolutional Science and Technology Program,CREST,Japan Science and Technology Agency(JST)(T.N.,N.A.and H.K.)+3 种基金the Naito Foundation(N.A)the Takeda Science Foundation(T.N.)a grant from Grant-in-Aid for Scientific Research(B),(JSPS KAKENHI)(T.N.),No.24300139Grant-in-Aid for Challenging Exploratory Research(JSPS KAKENHI)(T.N.)from the Ministry of Education,Culture,Sports,Science,and Technology of Japan,No.25640019
文摘Brain-derived neurotrophic factor(BDNF) attracts increasing attention from both research and clinical fields because of its important functions in the central nervous system. An adequate amount of BDNF is critical to develop and maintain normal neuronal circuits in the brain. Given that loss of BDNF function has beenreported in the brains of patients with neurodegenerative or psychiatric diseases, understanding basic properties of BDNF and associated intracellular processes is imperative. In this review, we revisit the gene structure, transcription, translation, transport and secretion mechanisms of BDNF. We also introduce implications of BDNF in several brain-related diseases including Alzheimer's disease, Huntington's disease, depression and schizophrenia.
文摘After China＇s entry into WTO, our industries will be confronted with fiercer competition. How to strengthen their international competitiveness to seek for survival and development has become a very urgent problem. This paper first simply discusses the meaning and theo^es of industrial international competitiveness, then chooses proper indexes according to some principles, explains the factor analysis method of industrial international competitiveness, and finally makes empirical analysis on China air transport industry.
基金Funded by the National Natural Science Foundation of China(Nos.51278304,U1134209,U1434204&51422814)the National Basic Research Program(973 Program)of China(No.011-CB013604)the Technology Research and Development Program(Basic Research Project)of Shenzhen(Nos.JCYJ20120613174456685&JCYJ20130329143859418)
文摘Diffusion has been systematically described as the main mechanism of chloride transport in reinforced concrete（RC） structure, especially when the concrete is in a saturated state. However, the single mechanism of diffusion is not able to describe the actual chloride ingress in the nonsaturated concrete. Instead, it is dominated by the interaction of diffusion and convection. With the synergetic effects of various factors taken into account, this study aimed to modify and develop an analytical convection- diffusion coupling model for chloride transport in nonsaturated concrete. The model was verified by simulation of laboratory tests and field measurement. The results of comparison study demonstrate that the analytical model developed in this study is efficient and accurate in predicting the chloride profiles in the nonsaturated concrete.
文摘In this experimental study we coupled nerve growth factor (NGF) with notatin by dicyclohexylcarbodiimide to label NGF and observed the effects of NGF on axonal retrograde transport after axonal injury of motoneurons with the aid of notatin chemiluminescence system. The results showed that NGF could be transported through axon not only to sensory neurons in dorsal root ganglia but also to motoneurons in spinal cord ventral horn.
基金supported by Research on the National Social Science Fund of Henan Polytechnic University(GSKY2017-28)
文摘The transportation industry is the basic industry of national economic development. At the same time, it is the only industry in China that has continuously increased CO2 emissions, and the high energy consumption problems have not been solved. Henan province, as a major energy consumption province, it is urgent to improve the supply quality of transportation industry. The paper uses the IPCC calculation method for carbon emission to calculate the CO2 emissions of transportation industry in Henan province from 2004 to 2014. Then, this paper uses the LMDI method to decompose the CO2 emission in the transportation industry and give the proposal to reduce the CO2 emission according to the CO2 emission drivers.
