The Coronavirus Disease-2019 (COVID-19) outbreak has become a global health emergency owing to its magnitude, attributed deaths, and its propensity to spread across the world. In-fact, owing to its quick spread across...The Coronavirus Disease-2019 (COVID-19) outbreak has become a global health emergency owing to its magnitude, attributed deaths, and its propensity to spread across the world. In-fact, owing to its quick spread across international boundaries and the resulting caseload, the disease has been declared as a Public Health Emergency of International Concern on 30 January 2020. It is worth noting that out of the 395 cases detected in other nations, 165 (41.8%) have a positive history of travel to China. As of now, the World Health Organization has not recommended for any restrictions on the travel or trade aspects, but has clearly specified that implementation of International Health Regulations should be strictly done at the airports and seaports. In conclusion, the COVID-19 outbreak has created an alarm across the globe as the causative virus is novel in nature. However, strengthening of standard infection control practices and adoption of preventive measures for travelers can significantly minimize the threat of further transmission of the disease.展开更多
Rationale: Malaria and dengue are the most prevalent vector-borne diseases in tropical countries. Plasmodium parasite and dengue virus(DENV) concurrent infection is possible and often under-recognized in geographical ...Rationale: Malaria and dengue are the most prevalent vector-borne diseases in tropical countries. Plasmodium parasite and dengue virus(DENV) concurrent infection is possible and often under-recognized in geographical areas where these infections are both endemic.Patients concern and diagnosis: We describe the first two cases of Plasmodium falciparum and DENV-3 co-infection in travelers returning to northeastern Italy from Burkina Faso during 2013-2014.Interventions: Malaria infection in both patients was treated with mefloquine. Due to the persistence of symptoms despite of the antimalaria treatment, dengue was also investigated;the treatment of dengue was symptomatic.Outcomes: The patients were discharged in good general condition.Lessons: The need for surveillance of potential malaria and dengue co-infection in travelers returning to Europe from endemic areas is highlighted, as infection with Plasmodium does not exclude arboviral co-infection.展开更多
Based on the travel texts of western travelers who came to Guangzhou in the 19;century, the travel situation of travelers in Guangzhou in the 19;century was deeply analyzed;Thirteen Hongs of Canton as the focus of the...Based on the travel texts of western travelers who came to Guangzhou in the 19;century, the travel situation of travelers in Guangzhou in the 19;century was deeply analyzed;Thirteen Hongs of Canton as the focus of the travel texts, and western travelers’ impressions of Guangzhou’s urban landscapes and water landscapes were described and discussed in detail;China’s national image in the eyes of Westerners was analyzed, and it was an objective reflection of the situation of the Qing Empire at that time.展开更多
LINGNAN Village in Tonglu County, east China's Zhejiang Province. has seen bed and breakfast (B&B) accommodations flourishing in recent years, with vil- lagers and newcomers alike taking advantage of this promisin...LINGNAN Village in Tonglu County, east China's Zhejiang Province. has seen bed and breakfast (B&B) accommodations flourishing in recent years, with vil- lagers and newcomers alike taking advantage of this promising business. Zhu Zhenhua, from Zhejiang's capital city Hangzhou, moved to a village with his wife in 2008. They rented a courtyard property and spent about 300,000 yuan ($46,154) on its renovation. As tourists came to the village and asked whether they could pay to stay in the house, Zhu turned it into a B&B business.展开更多
Traffic congestion has become a critical issue in developing countries,as it tends to increase social costs in terms of travel cost and time,energy consumption and environmental degradation.With limited resources,redu...Traffic congestion has become a critical issue in developing countries,as it tends to increase social costs in terms of travel cost and time,energy consumption and environmental degradation.With limited resources,reducing travel demand by influencing individuals’ travel behavior can be a better long-term solution.To achieve this objective,alternate travel options need to be provided so that people can commute comfortably and economically.This study aims to identify key motives and constraints in the consideration of carpooling policy with the help of stated preference questionnaire survey that was conducted in Lahore City.The designed questionnaire includes respondents’ socioeconomic demographics,and intentions and stated preferences on carpooling policy.Factor analysis was conducted on travelers’ responses,and a structural model was developed for carpooling.Survey and modeling results reveal that social,environmental and economic benefits,disincentives on car use,preferential parking treatment for carpooling,and comfort and convenience attributes are significant determinants in promoting carpooling.However,people with strong belief in personal privacy,security,freedom in traveling and carpooling service constraints would have less potential to use thecarpooling service.In addition,pro-auto and pro-carpooling attitudes,marital status,profession and travel purpose for carpooling are also underlying factors.The findings implicate that to promote carpooling policy it is required to consider appropriate incentives on this service and disincentives on use of private vehicle along with modification of people’s attitudes and intentions.展开更多
Objective:Individuals travel locally and internationally in order to find alternative treatments which are less-toxic and more beneficial to their health and wellness.Despite the popularity of the western system of me...Objective:Individuals travel locally and internationally in order to find alternative treatments which are less-toxic and more beneficial to their health and wellness.Despite the popularity of the western system of medicine,cupping therapies are gaining enormous attention in Pakistan as a system of traditional and complementary medicine to ensure the quality of life and wellness notions of the people.The present study aims to examine the effectiveness of dry cupping therapy(DCT)on the health,wellness,and quality of life preferences of health-seeking travelers in a sample of Faisalabad.Methods:DCT was performed for 15-20 minutes on subjects by using 3-5 disposable cupping glasses.Study participants filled the questionnaires before and after DCT interventions.Partial least square structural equation modeling technique is used in order to statistically analyze the data.Results:A total of 187 subjects participated in two DCT interventions at Coural Wellness Center Faisalabad and provided their final responses after 30 days from 2nd DCT.Respondents’perceptions of their physical feelings were generally found in a significantly positive and direct relation with DCT and health status(HS),i.e.,body pain(β=0.019),vitality(β=0.138),and bodily movement(β=0.207).This trend was observed in the psychological feelings of respondents as well,i.e.,emotional feelings(β=0.169).DCT significantly mediated the overall phenomenon and variance account for values were found between 20%and 80%for all the study constructs.The scores of all the health and wellness items on the questionnaire were significantly improved in 79.68%of studied participants after 1st and 2nd DCT interventions except for social functioning.Conclusion:Findings of the present study suggest that DCT has an important role in determining the health perceptions and HS of health travelers without potential side-effects.It can improve the health and overall quality of life of the people by positively influencing their physical and psychological health perceptions.It additionally leads to improve travelers’emotion,behavior,and other daily matters.展开更多
Businesses and corporations today break geographical boundaries and carry out business globally[14].Business travel can be physically demanding and psychologically stressful,compromising the well-being of business tra...Businesses and corporations today break geographical boundaries and carry out business globally[14].Business travel can be physically demanding and psychologically stressful,compromising the well-being of business travelers and the benefits of organizations.The present study examined how biopsychosocial factors,which are health concern,burnout,and social support,explained business travel stress among business travelers in Malaysia.We recruited 100 working adults(n=63 men,n=37 women)who traveled for business purposes from airports in Malaysia.Participants completed a series of questionnaires using the paper-and-pencil method.The mediation analyses showed that only burnout mediated the relationship between business travel and perceived stress.Specifically,the less intensely an individual traveled,s/he experienced a higher level of perceived stress;and this could be explained by the high level of burnout experienced.These findings have shed some light on how to deal with business travel stress at organizational and personal levels.Our findings suggested that organization-level interventions and policies should place an emphasis on employees who have to travel and in particular those who travel less intensively.Also,to provide support for business traveling employees,corporations should set up interventions and policies that aim to decrease burnout associated with business traveling.展开更多
Summary What is already known about this topic?Burkholderia pseudomallei(BP)infection leads to melioidosis,a tropical disease endemic to coastal provinces of southern China.Physicians in nonendemic areas,do not common...Summary What is already known about this topic?Burkholderia pseudomallei(BP)infection leads to melioidosis,a tropical disease endemic to coastal provinces of southern China.Physicians in nonendemic areas,do not commonly consider this disease as a primary differential diagnosis for febrile patients.What is added by this report?This article discusses a case of melioidosis in Northern China.The patient,who had recently visited a Southeast Asian region with high melioidosis prevalence,fell ill after exposure to contaminated water.The disease progressed quickly and with severity.What are the implications for public health practice?Healthcare workers need to remain vigilant regarding travel-related diseases for accurate differential diagnosis and to provide timely and effective treatment,especially for patients with recent travel history or symptoms during travel.展开更多
During big events, non-local private car travelers can be divided into two types which were returning in one day and in several days. It was demonstrated that those two kinds of travelers have distinct behavior on par...During big events, non-local private car travelers can be divided into two types which were returning in one day and in several days. It was demonstrated that those two kinds of travelers have distinct behavior on park and ride (P&R), due to their different travel demand and behavior attributes. In this paper focusing on the travelers returning in several days, the travel attributes and requirements for P&R were analyzed with stated preference survey. A P&R choice behavior disaggregated logit model was established and calibrated based on random utility theory. The model concludes three variables, which were travel time, parking fee and comprehensive attractiveness index for suburban satellite towns comparing to urban district. The results revealed that for travelers returning in several days the primary key point is increasing the attractiveness of suburban satellite towns.展开更多
IT is almost impossible to understand the traffic problems of the Sichuan Basin during ancient times, especially when you are in an airplane landing at Shuangliu Airport in Chengdu, the provincial capital of Sichuan. ...IT is almost impossible to understand the traffic problems of the Sichuan Basin during ancient times, especially when you are in an airplane landing at Shuangliu Airport in Chengdu, the provincial capital of Sichuan. With the construction of a modem infrastructure, the Sichuan Basin, surrounded by the Qinghai-Xizang Plateau, Yunnan-Guizhou Plateau, Qinling-Dabashan Hilly Area and Xiang’exi Hilly Area, has become a popular stop for tourists. Sichuan is also called "Shu." It is said that in ancient times a people known as the Shu once lived here. One of China’s most historic cities, Chengdu, the provincial capital,展开更多
This article presents the main components of computer system by using which quarantime doctors can provide international travelers with relevant health information for their good health during travel abroad and the ob...This article presents the main components of computer system by using which quarantime doctors can provide international travelers with relevant health information for their good health during travel abroad and the objective of each item designed and its roles and characters with a view to making both quarantine doctors and international travelers acquainted with the system and fully recognized the significance in operating it.展开更多
We study the existence and stability of monotone traveling wave solutions of Nicholson's blowflies equation with degenerate p-Laplacian diffusion.We prove the existence and nonexistence of non-decreasing smooth tr...We study the existence and stability of monotone traveling wave solutions of Nicholson's blowflies equation with degenerate p-Laplacian diffusion.We prove the existence and nonexistence of non-decreasing smooth traveling wave solutions by phase plane analysis methods.Moreover,we show the existence and regularity of an original solution via a compactness analysis.Finally,we prove the stability and exponential convergence rate of traveling waves by an approximated weighted energy method.展开更多
Nearly 150 km off the coast of Norway,in one of the windiest places on Earth,stands Hywind Tampen,the world’s largest floating wind power farm.Each weighing 8800 t and 190 m tall,with roughly one-third of that height...Nearly 150 km off the coast of Norway,in one of the windiest places on Earth,stands Hywind Tampen,the world’s largest floating wind power farm.Each weighing 8800 t and 190 m tall,with roughly one-third of that height sitting below the waterline,Hywind Tampen’s 11 turbines can generate 94.6 MW(Fig.1)[1].The blades—each 80 m long—travel at a blistering 290 km∙h–1,yet because of their size they complete only about 10 to 15 full rotations per minute.A single rotation provides enough electricity to power an average home for a day.However,Hywind Tampen,which became fully operational in August 2023,will not power houses.Instead,the installation built by energy company Equinor(Stavanger,Norway)will provide 38%of the annual electricity consumed by five nearby offshore oil platforms in the North Sea[1].展开更多
Coexistence of fast and slow traveling waves without synaptic transmission has been found in hhhippocampal tissues,which is closely related to both normal brain activity and abnormal neural activity such as epileptic ...Coexistence of fast and slow traveling waves without synaptic transmission has been found in hhhippocampal tissues,which is closely related to both normal brain activity and abnormal neural activity such as epileptic discharge. However, the propagation mechanism behind this coexistence phenomenon remains unclear. In this paper, a three-dimensional electric field coupled hippocampal neural network is established to investigate generation of coexisting spontaneous fast and slow traveling waves. This model captures two types of dendritic traveling waves propagating in both transverse and longitude directions: the N-methyl-D-aspartate(NMDA)-dependent wave with a speed of about 0.1 m/s and the Ca-dependent wave with a speed of about 0.009 m/s. These traveling waves are synaptic-independent and could be conducted only by the electric fields generated by neighboring neurons, which are basically consistent with the in vitro data measured experiments. It is also found that the slow Ca wave could trigger generation of fast NMDA waves in the propagation path of slow waves whereas fast NMDA waves cannot affect the propagation of slow Ca waves. These results suggest that dendritic Ca waves could acted as the source of the coexistence fast and slow waves. Furthermore, we also confirm the impact of cellular spacing heterogeneity on the onset of coexisting fast and slow waves. The local region with decreasing distances among neighbor neurons is more liable to promote the onset of spontaneous slow waves which, as sources, excite propagation of fast waves. These modeling studies provide possible biophysical mechanisms underlying the neural dynamics of spontaneous traveling waves in brain tissues.展开更多
Integrable systems play a crucial role in physics and mathematics.In particular,the traditional(1+1)-dimensional and(2+1)-dimensional integrable systems have received significant attention due to the rarity of integra...Integrable systems play a crucial role in physics and mathematics.In particular,the traditional(1+1)-dimensional and(2+1)-dimensional integrable systems have received significant attention due to the rarity of integrable systems in higher dimensions.Recent studies have shown that abundant higher-dimensional integrable systems can be constructed from(1+1)-dimensional integrable systems by using a deformation algorithm.Here we establish a new(2+1)-dimensional Chen-Lee-Liu(C-L-L)equation using the deformation algorithm from the(1+1)-dimensional C-L-L equation.The new system is integrable with its Lax pair obtained by applying the deformation algorithm to that of the(1+1)-dimension.It is challenging to obtain the exact solutions for the new integrable system because the new system combines both the original C-L-L equation and its reciprocal transformation.The traveling wave solutions are derived in implicit function expression,and some asymmetry peakon solutions are found.展开更多
The collision cross-sections(CCS)measurement using ion mobility spectrometry(IMS)in combination with mass spectrometry(MS)offers a great opportunity to increase confidence in metabolite identification.However,owing to...The collision cross-sections(CCS)measurement using ion mobility spectrometry(IMS)in combination with mass spectrometry(MS)offers a great opportunity to increase confidence in metabolite identification.However,owing to the lack of sensitivity and resolution,IMS has an analytical challenge in studying the CCS values of very low-molecular-weight metabolites(VLMs250 Da).Here,we describe an analytical method using ultrahigh-performance liquid chromatography(UPLC)coupled to a traveling wave ion mobility-quadrupole-time-of-flight mass spectrometer optimized for the measurement of VLMs in human urine samples.The experimental CCS values,along with mass spectral properties,were reported for the 174 metabolites.The experimental data included the mass-to-charge ratio(m/z),retention time(RT),tandem MS(MS/MS)spectra,and CCS values.Among the studied metabolites,263 traveling wave ion mobility spectrometry(TWIMS)-derived CCS values(TWCCSN2)were reported for the first time,and more than 70%of these were CCS values of VLMs.The TWCCSN2 values were highly repeatable,with inter-day variations of<1%relative standard deviation(RSD).The developed method revealed excellent TWCCSN2 accuracy with a CCS difference(DCCS)within±2%of the reported drift tube IMS(DTIMS)and TWIMS CCS values.The complexity of the urine matrix did not affect the precision of the method,as evidenced by DCCS within±1.92%.According to the Metabolomics Standards Initiative,55 urinary metabolites were identified with a confidence level of 1.Among these 55 metabolites,53(96%)were VLMs.The larger number of confirmed compounds found in this study was a result of the addition of TWCCSN2 values,which clearly increased metabolite identification confidence.展开更多
文摘The Coronavirus Disease-2019 (COVID-19) outbreak has become a global health emergency owing to its magnitude, attributed deaths, and its propensity to spread across the world. In-fact, owing to its quick spread across international boundaries and the resulting caseload, the disease has been declared as a Public Health Emergency of International Concern on 30 January 2020. It is worth noting that out of the 395 cases detected in other nations, 165 (41.8%) have a positive history of travel to China. As of now, the World Health Organization has not recommended for any restrictions on the travel or trade aspects, but has clearly specified that implementation of International Health Regulations should be strictly done at the airports and seaports. In conclusion, the COVID-19 outbreak has created an alarm across the globe as the causative virus is novel in nature. However, strengthening of standard infection control practices and adoption of preventive measures for travelers can significantly minimize the threat of further transmission of the disease.
文摘Rationale: Malaria and dengue are the most prevalent vector-borne diseases in tropical countries. Plasmodium parasite and dengue virus(DENV) concurrent infection is possible and often under-recognized in geographical areas where these infections are both endemic.Patients concern and diagnosis: We describe the first two cases of Plasmodium falciparum and DENV-3 co-infection in travelers returning to northeastern Italy from Burkina Faso during 2013-2014.Interventions: Malaria infection in both patients was treated with mefloquine. Due to the persistence of symptoms despite of the antimalaria treatment, dengue was also investigated;the treatment of dengue was symptomatic.Outcomes: The patients were discharged in good general condition.Lessons: The need for surveillance of potential malaria and dengue co-infection in travelers returning to Europe from endemic areas is highlighted, as infection with Plasmodium does not exclude arboviral co-infection.
基金Sponsored by“Twelfth Five-year Plan”Program of Guangdong Provincial Philosophy and Social Sciences(GD15XLS07)Science and Technology Innovation Research Team Program of Zhaoqing University(2021)。
文摘Based on the travel texts of western travelers who came to Guangzhou in the 19;century, the travel situation of travelers in Guangzhou in the 19;century was deeply analyzed;Thirteen Hongs of Canton as the focus of the travel texts, and western travelers’ impressions of Guangzhou’s urban landscapes and water landscapes were described and discussed in detail;China’s national image in the eyes of Westerners was analyzed, and it was an objective reflection of the situation of the Qing Empire at that time.
文摘LINGNAN Village in Tonglu County, east China's Zhejiang Province. has seen bed and breakfast (B&B) accommodations flourishing in recent years, with vil- lagers and newcomers alike taking advantage of this promising business. Zhu Zhenhua, from Zhejiang's capital city Hangzhou, moved to a village with his wife in 2008. They rented a courtyard property and spent about 300,000 yuan ($46,154) on its renovation. As tourists came to the village and asked whether they could pay to stay in the house, Zhu turned it into a B&B business.
基金conducted at University of Engineering and Technology Lahore with support of Department of Transportation Engineering and Management Department
文摘Traffic congestion has become a critical issue in developing countries,as it tends to increase social costs in terms of travel cost and time,energy consumption and environmental degradation.With limited resources,reducing travel demand by influencing individuals’ travel behavior can be a better long-term solution.To achieve this objective,alternate travel options need to be provided so that people can commute comfortably and economically.This study aims to identify key motives and constraints in the consideration of carpooling policy with the help of stated preference questionnaire survey that was conducted in Lahore City.The designed questionnaire includes respondents’ socioeconomic demographics,and intentions and stated preferences on carpooling policy.Factor analysis was conducted on travelers’ responses,and a structural model was developed for carpooling.Survey and modeling results reveal that social,environmental and economic benefits,disincentives on car use,preferential parking treatment for carpooling,and comfort and convenience attributes are significant determinants in promoting carpooling.However,people with strong belief in personal privacy,security,freedom in traveling and carpooling service constraints would have less potential to use thecarpooling service.In addition,pro-auto and pro-carpooling attitudes,marital status,profession and travel purpose for carpooling are also underlying factors.The findings implicate that to promote carpooling policy it is required to consider appropriate incentives on this service and disincentives on use of private vehicle along with modification of people’s attitudes and intentions.
文摘Objective:Individuals travel locally and internationally in order to find alternative treatments which are less-toxic and more beneficial to their health and wellness.Despite the popularity of the western system of medicine,cupping therapies are gaining enormous attention in Pakistan as a system of traditional and complementary medicine to ensure the quality of life and wellness notions of the people.The present study aims to examine the effectiveness of dry cupping therapy(DCT)on the health,wellness,and quality of life preferences of health-seeking travelers in a sample of Faisalabad.Methods:DCT was performed for 15-20 minutes on subjects by using 3-5 disposable cupping glasses.Study participants filled the questionnaires before and after DCT interventions.Partial least square structural equation modeling technique is used in order to statistically analyze the data.Results:A total of 187 subjects participated in two DCT interventions at Coural Wellness Center Faisalabad and provided their final responses after 30 days from 2nd DCT.Respondents’perceptions of their physical feelings were generally found in a significantly positive and direct relation with DCT and health status(HS),i.e.,body pain(β=0.019),vitality(β=0.138),and bodily movement(β=0.207).This trend was observed in the psychological feelings of respondents as well,i.e.,emotional feelings(β=0.169).DCT significantly mediated the overall phenomenon and variance account for values were found between 20%and 80%for all the study constructs.The scores of all the health and wellness items on the questionnaire were significantly improved in 79.68%of studied participants after 1st and 2nd DCT interventions except for social functioning.Conclusion:Findings of the present study suggest that DCT has an important role in determining the health perceptions and HS of health travelers without potential side-effects.It can improve the health and overall quality of life of the people by positively influencing their physical and psychological health perceptions.It additionally leads to improve travelers’emotion,behavior,and other daily matters.
文摘Businesses and corporations today break geographical boundaries and carry out business globally[14].Business travel can be physically demanding and psychologically stressful,compromising the well-being of business travelers and the benefits of organizations.The present study examined how biopsychosocial factors,which are health concern,burnout,and social support,explained business travel stress among business travelers in Malaysia.We recruited 100 working adults(n=63 men,n=37 women)who traveled for business purposes from airports in Malaysia.Participants completed a series of questionnaires using the paper-and-pencil method.The mediation analyses showed that only burnout mediated the relationship between business travel and perceived stress.Specifically,the less intensely an individual traveled,s/he experienced a higher level of perceived stress;and this could be explained by the high level of burnout experienced.These findings have shed some light on how to deal with business travel stress at organizational and personal levels.Our findings suggested that organization-level interventions and policies should place an emphasis on employees who have to travel and in particular those who travel less intensively.Also,to provide support for business traveling employees,corporations should set up interventions and policies that aim to decrease burnout associated with business traveling.
文摘Summary What is already known about this topic?Burkholderia pseudomallei(BP)infection leads to melioidosis,a tropical disease endemic to coastal provinces of southern China.Physicians in nonendemic areas,do not commonly consider this disease as a primary differential diagnosis for febrile patients.What is added by this report?This article discusses a case of melioidosis in Northern China.The patient,who had recently visited a Southeast Asian region with high melioidosis prevalence,fell ill after exposure to contaminated water.The disease progressed quickly and with severity.What are the implications for public health practice?Healthcare workers need to remain vigilant regarding travel-related diseases for accurate differential diagnosis and to provide timely and effective treatment,especially for patients with recent travel history or symptoms during travel.
文摘During big events, non-local private car travelers can be divided into two types which were returning in one day and in several days. It was demonstrated that those two kinds of travelers have distinct behavior on park and ride (P&R), due to their different travel demand and behavior attributes. In this paper focusing on the travelers returning in several days, the travel attributes and requirements for P&R were analyzed with stated preference survey. A P&R choice behavior disaggregated logit model was established and calibrated based on random utility theory. The model concludes three variables, which were travel time, parking fee and comprehensive attractiveness index for suburban satellite towns comparing to urban district. The results revealed that for travelers returning in several days the primary key point is increasing the attractiveness of suburban satellite towns.
文摘IT is almost impossible to understand the traffic problems of the Sichuan Basin during ancient times, especially when you are in an airplane landing at Shuangliu Airport in Chengdu, the provincial capital of Sichuan. With the construction of a modem infrastructure, the Sichuan Basin, surrounded by the Qinghai-Xizang Plateau, Yunnan-Guizhou Plateau, Qinling-Dabashan Hilly Area and Xiang’exi Hilly Area, has become a popular stop for tourists. Sichuan is also called "Shu." It is said that in ancient times a people known as the Shu once lived here. One of China’s most historic cities, Chengdu, the provincial capital,
文摘This article presents the main components of computer system by using which quarantime doctors can provide international travelers with relevant health information for their good health during travel abroad and the objective of each item designed and its roles and characters with a view to making both quarantine doctors and international travelers acquainted with the system and fully recognized the significance in operating it.
基金partially supported by the NSFC(11971179,12371205)partially supported by the National Key R&D Program of China(2021YFA1002900)+1 种基金the Guangdong Province Basic and Applied Basic Research Fund(2021A1515010235)the Guangzhou City Basic and Applied Basic Research Fund(2024A04J6336)。
文摘We study the existence and stability of monotone traveling wave solutions of Nicholson's blowflies equation with degenerate p-Laplacian diffusion.We prove the existence and nonexistence of non-decreasing smooth traveling wave solutions by phase plane analysis methods.Moreover,we show the existence and regularity of an original solution via a compactness analysis.Finally,we prove the stability and exponential convergence rate of traveling waves by an approximated weighted energy method.
文摘Nearly 150 km off the coast of Norway,in one of the windiest places on Earth,stands Hywind Tampen,the world’s largest floating wind power farm.Each weighing 8800 t and 190 m tall,with roughly one-third of that height sitting below the waterline,Hywind Tampen’s 11 turbines can generate 94.6 MW(Fig.1)[1].The blades—each 80 m long—travel at a blistering 290 km∙h–1,yet because of their size they complete only about 10 to 15 full rotations per minute.A single rotation provides enough electricity to power an average home for a day.However,Hywind Tampen,which became fully operational in August 2023,will not power houses.Instead,the installation built by energy company Equinor(Stavanger,Norway)will provide 38%of the annual electricity consumed by five nearby offshore oil platforms in the North Sea[1].
基金supported in part by the National Natural Science Foundation of China (Grant Nos. 62171312 and 61771330)the Tianjin Municipal Education Commission Scientific Research Project (Grant No. 2020KJ114)。
文摘Coexistence of fast and slow traveling waves without synaptic transmission has been found in hhhippocampal tissues,which is closely related to both normal brain activity and abnormal neural activity such as epileptic discharge. However, the propagation mechanism behind this coexistence phenomenon remains unclear. In this paper, a three-dimensional electric field coupled hippocampal neural network is established to investigate generation of coexisting spontaneous fast and slow traveling waves. This model captures two types of dendritic traveling waves propagating in both transverse and longitude directions: the N-methyl-D-aspartate(NMDA)-dependent wave with a speed of about 0.1 m/s and the Ca-dependent wave with a speed of about 0.009 m/s. These traveling waves are synaptic-independent and could be conducted only by the electric fields generated by neighboring neurons, which are basically consistent with the in vitro data measured experiments. It is also found that the slow Ca wave could trigger generation of fast NMDA waves in the propagation path of slow waves whereas fast NMDA waves cannot affect the propagation of slow Ca waves. These results suggest that dendritic Ca waves could acted as the source of the coexistence fast and slow waves. Furthermore, we also confirm the impact of cellular spacing heterogeneity on the onset of coexisting fast and slow waves. The local region with decreasing distances among neighbor neurons is more liable to promote the onset of spontaneous slow waves which, as sources, excite propagation of fast waves. These modeling studies provide possible biophysical mechanisms underlying the neural dynamics of spontaneous traveling waves in brain tissues.
基金Project supported by the National Natural Science Foundation of China (Grant Nos.12275144,12235007,and 11975131)K.C.Wong Magna Fund in Ningbo University。
文摘Integrable systems play a crucial role in physics and mathematics.In particular,the traditional(1+1)-dimensional and(2+1)-dimensional integrable systems have received significant attention due to the rarity of integrable systems in higher dimensions.Recent studies have shown that abundant higher-dimensional integrable systems can be constructed from(1+1)-dimensional integrable systems by using a deformation algorithm.Here we establish a new(2+1)-dimensional Chen-Lee-Liu(C-L-L)equation using the deformation algorithm from the(1+1)-dimensional C-L-L equation.The new system is integrable with its Lax pair obtained by applying the deformation algorithm to that of the(1+1)-dimension.It is challenging to obtain the exact solutions for the new integrable system because the new system combines both the original C-L-L equation and its reciprocal transformation.The traveling wave solutions are derived in implicit function expression,and some asymmetry peakon solutions are found.
基金supported by the Postdoctoral Fellowship Program(Grant No.:(IO)R016320001)by Mahidol University,Thailand.supported by Mahidol University,Thailand(to Associate Professor Sakda Khoomrung)funding support from the National Science,Research and Innovation Fund(NSRF)via the Program Management Unit for Human Resources&Institutional Development,Research and Innovation,Thailand(Grant No.:B36G660007).
文摘The collision cross-sections(CCS)measurement using ion mobility spectrometry(IMS)in combination with mass spectrometry(MS)offers a great opportunity to increase confidence in metabolite identification.However,owing to the lack of sensitivity and resolution,IMS has an analytical challenge in studying the CCS values of very low-molecular-weight metabolites(VLMs250 Da).Here,we describe an analytical method using ultrahigh-performance liquid chromatography(UPLC)coupled to a traveling wave ion mobility-quadrupole-time-of-flight mass spectrometer optimized for the measurement of VLMs in human urine samples.The experimental CCS values,along with mass spectral properties,were reported for the 174 metabolites.The experimental data included the mass-to-charge ratio(m/z),retention time(RT),tandem MS(MS/MS)spectra,and CCS values.Among the studied metabolites,263 traveling wave ion mobility spectrometry(TWIMS)-derived CCS values(TWCCSN2)were reported for the first time,and more than 70%of these were CCS values of VLMs.The TWCCSN2 values were highly repeatable,with inter-day variations of<1%relative standard deviation(RSD).The developed method revealed excellent TWCCSN2 accuracy with a CCS difference(DCCS)within±2%of the reported drift tube IMS(DTIMS)and TWIMS CCS values.The complexity of the urine matrix did not affect the precision of the method,as evidenced by DCCS within±1.92%.According to the Metabolomics Standards Initiative,55 urinary metabolites were identified with a confidence level of 1.Among these 55 metabolites,53(96%)were VLMs.The larger number of confirmed compounds found in this study was a result of the addition of TWCCSN2 values,which clearly increased metabolite identification confidence.