Cancer and neurodegeneration include a group of diseases that are mechanistically distinct but may share common therapeutic targets.Autophagy is a common quality control mechanism shared by mitotic and post-mitotic ce...Cancer and neurodegeneration include a group of diseases that are mechanistically distinct but may share common therapeutic targets.Autophagy is a common quality control mechanism shared by mitotic and post-mitotic cells and it can be exploited to accelerate clearance of unwanted oncogenes and reduce accumulation of toxic proteins in cancer and neurodegeneration,respectively.Tyrosine kinase inhibition is a therapeutically relevant strategy that can induce autophagy, leading to normal cell survival. This article provides insights into how tyrosine kinase inhibition is clinically used to arrest mitotic cell division and tumor growth, and may promote survival of post-mitotic neurons in neurodegeneration.展开更多
With trade of over $100 billion in 2009, the importance of China and Africa bilateral exchanges are growing daily. This blooming relationship increases the need of understanding the ways of doing business.This regular...With trade of over $100 billion in 2009, the importance of China and Africa bilateral exchanges are growing daily. This blooming relationship increases the need of understanding the ways of doing business.This regular column will provide a practical insight of doing business in China, including tips and advice based on experience.展开更多
Economic considerations occupy an important place in relations between China and theEuropean Union(EU). This paper will attempt to explain the reasons behind this and willexplore perspectives from both sides. The majo...Economic considerations occupy an important place in relations between China and theEuropean Union(EU). This paper will attempt to explain the reasons behind this and willexplore perspectives from both sides. The major points are as follows: (1) The end of theCold War and the growing phenomenon of economic globalization have made both sidesplace much more importance on developing bilateral economic relations. (2) Having re-defined economic development as its core national interests through the launch of reformsand an open-door policy, China views the EU as an increasingly significant economicpartner, particularly in the area of trade, investment, technology imports and economiccooperation. (3) The fundamental aim of the EUs economic policies is to explore to thefullest opportunities provided by Chinas development and to protect the economic securityof Europe. (4) Because of the different positions they hold and their varying levels ofdevelopment, some differences in policy considerations by the two partners are inevitable.However, both China and the EU have been making efforts to narrow these differences andwiden their shared interests, so as to promote their common economic goals.展开更多
THE goddess Mazu has been held in great esteem by emperors since the Song Dynasty (960-1279). Wherever the Chinese live, in Asia, Africa, South America and North America, there are worshipers of Mazu. According to sta...THE goddess Mazu has been held in great esteem by emperors since the Song Dynasty (960-1279). Wherever the Chinese live, in Asia, Africa, South America and North America, there are worshipers of Mazu. According to statistics, there are more than 1,500 Mazu temples and more than 200 million Mazu devotees in the world. Mazu culture, with its unique style, affects people and promotes friendly relations of compatriots on both sides of the Taiwan Straits.展开更多
基金supported by Georgetown University funding to CEHM
文摘Cancer and neurodegeneration include a group of diseases that are mechanistically distinct but may share common therapeutic targets.Autophagy is a common quality control mechanism shared by mitotic and post-mitotic cells and it can be exploited to accelerate clearance of unwanted oncogenes and reduce accumulation of toxic proteins in cancer and neurodegeneration,respectively.Tyrosine kinase inhibition is a therapeutically relevant strategy that can induce autophagy, leading to normal cell survival. This article provides insights into how tyrosine kinase inhibition is clinically used to arrest mitotic cell division and tumor growth, and may promote survival of post-mitotic neurons in neurodegeneration.
文摘With trade of over $100 billion in 2009, the importance of China and Africa bilateral exchanges are growing daily. This blooming relationship increases the need of understanding the ways of doing business.This regular column will provide a practical insight of doing business in China, including tips and advice based on experience.
文摘Economic considerations occupy an important place in relations between China and theEuropean Union(EU). This paper will attempt to explain the reasons behind this and willexplore perspectives from both sides. The major points are as follows: (1) The end of theCold War and the growing phenomenon of economic globalization have made both sidesplace much more importance on developing bilateral economic relations. (2) Having re-defined economic development as its core national interests through the launch of reformsand an open-door policy, China views the EU as an increasingly significant economicpartner, particularly in the area of trade, investment, technology imports and economiccooperation. (3) The fundamental aim of the EUs economic policies is to explore to thefullest opportunities provided by Chinas development and to protect the economic securityof Europe. (4) Because of the different positions they hold and their varying levels ofdevelopment, some differences in policy considerations by the two partners are inevitable.However, both China and the EU have been making efforts to narrow these differences andwiden their shared interests, so as to promote their common economic goals.
文摘THE goddess Mazu has been held in great esteem by emperors since the Song Dynasty (960-1279). Wherever the Chinese live, in Asia, Africa, South America and North America, there are worshipers of Mazu. According to statistics, there are more than 1,500 Mazu temples and more than 200 million Mazu devotees in the world. Mazu culture, with its unique style, affects people and promotes friendly relations of compatriots on both sides of the Taiwan Straits.
