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Two-Dimensional Perovskite Single Crystals for High-Performance X-ray Imaging and Exploring MeV X-ray Detection
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作者 Xieming Xu Yiheng Wu +5 位作者 Yi Zhang Xiaohui Li Fang Wang Xiaoming Jiang Shaofan Wu Shuaihua Wang 《Energy & Environmental Materials》 SCIE EI CAS CSCD 2024年第1期139-146,共8页
Scintillation semiconductors play increasingly important medical diagnosis and industrial inspection roles.Recently,two-dimensional(2D)perovskites have been shown to be promising materials for medical X-ray imaging,bu... Scintillation semiconductors play increasingly important medical diagnosis and industrial inspection roles.Recently,two-dimensional(2D)perovskites have been shown to be promising materials for medical X-ray imaging,but they are mostly used in low-energy(≤130 keV)regions.Direct detection of MeV X-rays,which ensure thorough penetration of the thick shell walls of containers,trucks,and aircraft,is also highly desired in practical industrial applications.Unfortunately,scintillation semiconductors for high-energy X-ray detection are currently scarce.Here,This paper reports a 2D(C_(4)H_(9)NH_(3))_(2)PbBr_(4)single crystal with outstanding sensitivity and stability toward X-ray radiation that provides an ultra-wide detectable X-ray range of between 8.20 nGy_(air)s^(-1)(50 keV)and 15.24 mGy_(air)s^(-1)(9 MeV).The(C_(4)H_(9)NH_(3))_(2)PbBr_(4)single-crystal detector with a vertical structure is used for high-performance X-ray imaging,delivering a good spatial resolution of 4.3 Ip mm^(-1)in a plane-scan imaging system.Low ionic migration in the 2D perovskite enables the vertical device to be operated with hundreds of keV to MeV X-ray radiation at high bias voltages,leading to a sensitivity of 46.90μC Gy_(air)-1 cm^(-2)(-1.16 Vμm^(-1))with 9 MeV X-ray radiation,demonstrating that 2D perovskites have enormous potential for high-energy industrial applications. 展开更多
关键词 MeV X-ray detection single-crystal X-ray detectors two-dimensional perovskites X-ray imaging
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Transparent and Accurate COVID-19 Diagnosis:Integrating Explainable AI with Advanced Deep Learning in CT Imaging
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作者 Mohammad Mehedi Hassan Salman A.AlQahtani +1 位作者 Mabrook S.AlRakhami Ahmed Zohier Elhendi 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第6期3101-3123,共23页
In the current landscape of the COVID-19 pandemic,the utilization of deep learning in medical imaging,especially in chest computed tomography(CT)scan analysis for virus detection,has become increasingly significant.De... In the current landscape of the COVID-19 pandemic,the utilization of deep learning in medical imaging,especially in chest computed tomography(CT)scan analysis for virus detection,has become increasingly significant.Despite its potential,deep learning’s“black box”nature has been a major impediment to its broader acceptance in clinical environments,where transparency in decision-making is imperative.To bridge this gap,our research integrates Explainable AI(XAI)techniques,specifically the Local Interpretable Model-Agnostic Explanations(LIME)method,with advanced deep learning models.This integration forms a sophisticated and transparent framework for COVID-19 identification,enhancing the capability of standard Convolutional Neural Network(CNN)models through transfer learning and data augmentation.Our approach leverages the refined DenseNet201 architecture for superior feature extraction and employs data augmentation strategies to foster robust model generalization.The pivotal element of our methodology is the use of LIME,which demystifies the AI decision-making process,providing clinicians with clear,interpretable insights into the AI’s reasoning.This unique combination of an optimized Deep Neural Network(DNN)with LIME not only elevates the precision in detecting COVID-19 cases but also equips healthcare professionals with a deeper understanding of the diagnostic process.Our method,validated on the SARS-COV-2 CT-Scan dataset,demonstrates exceptional diagnostic accuracy,with performance metrics that reinforce its potential for seamless integration into modern healthcare systems.This innovative approach marks a significant advancement in creating explainable and trustworthy AI tools for medical decisionmaking in the ongoing battle against COVID-19. 展开更多
关键词 Explainable AI COVID-19 ct images deep learning
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A Robust Automated Framework for Classification of CT Covid-19 Images Using MSI-ResNet 被引量:1
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作者 Aghila Rajagopal Sultan Ahmad +3 位作者 Sudan Jha Ramachandran Alagarsamy Abdullah Alharbi Bader Alouffi 《Computer Systems Science & Engineering》 SCIE EI 2023年第6期3215-3229,共15页
Nowadays,the COVID-19 virus disease is spreading rampantly.There are some testing tools and kits available for diagnosing the virus,but it is in a lim-ited count.To diagnose the presence of disease from radiological i... Nowadays,the COVID-19 virus disease is spreading rampantly.There are some testing tools and kits available for diagnosing the virus,but it is in a lim-ited count.To diagnose the presence of disease from radiological images,auto-mated COVID-19 diagnosis techniques are needed.The enhancement of AI(Artificial Intelligence)has been focused in previous research,which uses X-ray images for detecting COVID-19.The most common symptoms of COVID-19 are fever,dry cough and sore throat.These symptoms may lead to an increase in the rigorous type of pneumonia with a severe barrier.Since medical imaging is not suggested recently in Canada for critical COVID-19 diagnosis,computer-aided systems are implemented for the early identification of COVID-19,which aids in noticing the disease progression and thus decreases the death rate.Here,a deep learning-based automated method for the extraction of features and classi-fication is enhanced for the detection of COVID-19 from the images of computer tomography(CT).The suggested method functions on the basis of three main pro-cesses:data preprocessing,the extraction of features and classification.This approach integrates the union of deep features with the help of Inception 14 and VGG-16 models.At last,a classifier of Multi-scale Improved ResNet(MSI-ResNet)is developed to detect and classify the CT images into unique labels of class.With the support of available open-source COVID-CT datasets that consists of 760 CT pictures,the investigational validation of the suggested method is estimated.The experimental results reveal that the proposed approach offers greater performance with high specificity,accuracy and sensitivity. 展开更多
关键词 Covid-19 ct images multi-scale improved ResNet AI inception 14 and VGG-16 models
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Analysis of Imaging Characteristics and Dynamic Changes of 3 Cases of Severe Novel Coronavirus Pneumonia in Qinghai Province
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作者 Yingfang Yu Ruiyun Zhao +3 位作者 Changde Li Fuqiang Ma Lingyun Guo Yang Li 《Journal of Clinical and Nursing Research》 2024年第3期120-126,共7页
Objective:To analyze the characteristics,dynamic changes,and outcomes of the first imaging manifestations of 3 patients with severe COVID-19 in our hospital.Methods:Computed tomography(CT)findings of 3 patients with s... Objective:To analyze the characteristics,dynamic changes,and outcomes of the first imaging manifestations of 3 patients with severe COVID-19 in our hospital.Methods:Computed tomography(CT)findings of 3 patients with severe COVID-19 who tested positive by the nucleic acid test in our hospital were selected,mainly focusing on the morphology,distribution characteristics,and dynamic changes of the first CT findings.Results:3 patients with severe pneumonia were older,with one aged 80.The first chest CT examination for all 3 patients differed.Imaging showed a leafy distribution of consolidation,primarily affecting the lower lobes of both lungs and extending subpleurally.A grid-like pattern was observed,along with changes in the consolidation and air bronchogram.These changes had slower absorption,especially in patients with underlying diseases.Conclusion:CT manifestations of severe COVID-19 have specific characteristics and the analysis of their characteristics and dynamic changes provide valuable insights for clinical treatment. 展开更多
关键词 COVID-19 imagING ct findings Dynamic changes
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Analysis of The Value of Multi-Slice Spiral CT and Magnetic Resonance Imaging in The Diagnosis of Carpal Joint Injury
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作者 Rongfeng An Juntao Lu +1 位作者 Jingzhong Liu Fang Yan 《Journal of Clinical and Nursing Research》 2024年第5期145-149,共5页
Objective:To analyze the value of multi-slice spiral computed tomography(CT)and magnetic resonance imaging(MRI)in the diagnosis of carpal joint injury.Methods:A total of 130 patients with suspected wrist injuries admi... Objective:To analyze the value of multi-slice spiral computed tomography(CT)and magnetic resonance imaging(MRI)in the diagnosis of carpal joint injury.Methods:A total of 130 patients with suspected wrist injuries admitted to the Department of Orthopedics of our hospital from January 2023 to January 2024 were selected and randomly divided into a single group(n=65)and a joint group(n=65).The single group was diagnosed using multi-slice spiral CT,and the joint group was diagnosed using multi-slice spiral CT and magnetic resonance imaging,with pathological diagnosis as the gold standard.The diagnostic results of both groups were compared to the gold standard,and the diagnostic energy efficiency of both groups was compared.Results:The diagnostic results of the single group compared with the gold standard were significant(P<0.05).The diagnostic results of the joint group compared with the gold standard were not significant(P>0.05).The sensitivity and accuracy of diagnosis in the joint group were significantly higher than that in the single group(P<0.05).The specificity of diagnosis in the joint group was higher as compared to that in the single group(P>0.05).Conclusion:The combination of multi-slice spiral CT and MRI was highly accurate in diagnosing wrist injuries,and the misdiagnosis rate and leakage rate were relatively low.Hence,this diagnostic program is recommended to be popularized. 展开更多
关键词 Multi-slice ct Magnetic resonance imaging Carpal joint injury Joint diagnosis
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Stacked Gated Recurrent Unit Classifier with CT Images for Liver Cancer Classification
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作者 Mahmoud Ragab Jaber Alyami 《Computer Systems Science & Engineering》 SCIE EI 2023年第3期2309-2322,共14页
Liver cancer is one of the major diseases with increased mortality in recent years,across the globe.Manual detection of liver cancer is a tedious and laborious task due to which Computer Aided Diagnosis(CAD)models hav... Liver cancer is one of the major diseases with increased mortality in recent years,across the globe.Manual detection of liver cancer is a tedious and laborious task due to which Computer Aided Diagnosis(CAD)models have been developed to detect the presence of liver cancer accurately and classify its stages.Besides,liver cancer segmentation outcome,using medical images,is employed in the assessment of tumor volume,further treatment plans,and response moni-toring.Hence,there is a need exists to develop automated tools for liver cancer detection in a precise manner.With this motivation,the current study introduces an Intelligent Artificial Intelligence with Equilibrium Optimizer based Liver cancer Classification(IAIEO-LCC)model.The proposed IAIEO-LCC technique initially performs Median Filtering(MF)-based pre-processing and data augmentation process.Besides,Kapur’s entropy-based segmentation technique is used to identify the affected regions in liver.Moreover,VGG-19 based feature extractor and Equilibrium Optimizer(EO)-based hyperparameter tuning processes are also involved to derive the feature vectors.At last,Stacked Gated Recurrent Unit(SGRU)classifier is exploited to detect and classify the liver cancer effectively.In order to demonstrate the superiority of the proposed IAIEO-LCC technique in terms of performance,a wide range of simulations was conducted and the results were inspected under different measures.The comparison study results infer that the proposed IAIEO-LCC technique achieved an improved accuracy of 98.52%. 展开更多
关键词 Liver cancer image segmentation artificial intelligence deep learning ct images parameter tuning
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Research on Automatic Elimination of Laptop Computer in Security CT Images Based on Projection Algorithm and YOLOv7-Seg
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作者 Fei Wang Baosheng Liu +1 位作者 Yijun Tang Lei Zhao 《Journal of Computer and Communications》 2023年第9期1-17,共17页
In civil aviation security screening, laptops, with their intricate structural composition, provide the potential for criminals to conceal dangerous items. Presently, the security process necessitates passengers to in... In civil aviation security screening, laptops, with their intricate structural composition, provide the potential for criminals to conceal dangerous items. Presently, the security process necessitates passengers to individually present their laptops for inspection. The paper introduced a method for laptop removal. By combining projection algorithms with the YOLOv7-Seg model, a laptop’s three views were generated through projection, and instance segmentation of these views was achieved using YOLOv7-Seg. The resulting 2D masks from instance segmentation at different angles were employed to reconstruct a 3D mask through angle restoration. Ultimately, the intersection of this 3D mask with the original 3D data enabled the successful extraction of the laptop’s 3D information. Experimental results demonstrated that the fusion of projection and instance segmentation facilitated the automatic removal of laptops from CT data. Moreover, higher instance segmentation model accuracy leads to more precise removal outcomes. By implementing the laptop removal functionality, the civil aviation security screening process becomes more efficient and convenient. Passengers will no longer be required to individually handle their laptops, effectively enhancing the efficiency and accuracy of security screening. 展开更多
关键词 Instance Segmentation PROJEctION ct image 3D Segmentation Real-Time Detection
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Early prediction of myocardial viability after acute myocardial infarction by two-dimensional speckle tracking imaging 被引量:15
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作者 Jong Shin Woo Tae-Kyung Yu Woo-Shik Kim Kwon Sam Kim Weon Kim 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2015年第5期474-481,共8页
Background Identifying the transmural extent of myocardial necrosis and the degree of myocardial viability in acute myocardial infarction (AMI) is important clinically. The aim of this study was to assess myocardial... Background Identifying the transmural extent of myocardial necrosis and the degree of myocardial viability in acute myocardial infarction (AMI) is important clinically. The aim of this study was to assess myocardial viability using two-dimensional speckle tracking imaging (2D-STI) in patients with AMI. Methods 2D-STI was performed at initial presentation, three days, and six months after primary percutaneous coronary intervention (PCI) in 30 patients with AMI, who had a left anterior descending coronary artery (LAD) culprit lesion. In addition, 20 patients who had minimal stenotic lesions (〈 30% stenosis) on coronary angiography were also included in the control group. At six months dobutamine echocardiography was performed for viability assessment in seven segments of the LAD territory. According to the recovery of wall motion abnormality, segments were classified as viable or non-viable. Results A total of 131 segments were viable, and 44 were nonviable. Multivariate analysis revealed significant differences between the viable and nonviable segments in the peak systolic strain, the peak systolic strain rate at initial presentation, and peak systolic strain rate three days after primary PCI. Among these, the initial peak systolic strain rate had the highest predictive value for myocardial viability (hazard ratio: 31.22, P 〈 0.01). Conclusions 2D-STI is feasible for assessing myocardial viability, and the peak systolic strain rate might be the most reliable predictor of myocardial viability in patients with AMI. 展开更多
关键词 Acute myocardial infarction two-dimensional speckle tracking imaging Viable myocardium
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Image encryption technique based on new two-dimensional fractional-order discrete chaotic map and Menezes–Vanstone elliptic curve cryptosystem 被引量:1
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作者 Zeyu Liu Tiecheng Xia Jinbo Wang 《Chinese Physics B》 SCIE EI CAS CSCD 2018年第3期161-176,共16页
We propose a new fractional two-dimensional triangle function combination discrete chaotic map(2D-TFCDM)with the discrete fractional difference.Moreover,the chaos behaviors of the proposed map are observed and the bif... We propose a new fractional two-dimensional triangle function combination discrete chaotic map(2D-TFCDM)with the discrete fractional difference.Moreover,the chaos behaviors of the proposed map are observed and the bifurcation diagrams,the largest Lyapunov exponent plot,and the phase portraits are derived,respectively.Finally,with the secret keys generated by Menezes-Vanstone elliptic curve cryptosystem,we apply the discrete fractional map into color image encryption.After that,the image encryption algorithm is analyzed in four aspects and the result indicates that the proposed algorithm is more superior than the other algorithms. 展开更多
关键词 CHAOS fractional two-dimensional triangle function combination discrete chaotic map image encryption Menezes-Vanstone elliptic curve cryptosystem
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Value of two-dimensional speckle tracking imaging in quantitative assessment of left ventricular function in patients with OSAS
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作者 Guo-Ping Xie Qing-Shan Lin Chao Yu 《Journal of Hainan Medical University》 2019年第10期75-78,共4页
Objective: To research the clinical application of two-dimensional speckle tracking imaging (2D-STI) in quantitative assessment of left ventricular function in patients with obstructive sleep apnea-hypopnea syndrome (... Objective: To research the clinical application of two-dimensional speckle tracking imaging (2D-STI) in quantitative assessment of left ventricular function in patients with obstructive sleep apnea-hypopnea syndrome (OSAS). Method: From July 2016 to December 2018, 86 patients with OSAS were selected as OSAS group. According to sleep apnea hypopnea index (AHI), they were divided into mild OSAS group (24 cases), moderate OSAS group (29 cases) and severe OSAS group (33 cases). Another 50 healthy volunteers who underwent physical examination in our hospital during the same period were selected as the control group. The left ventricular function of all patients was quantitatively assessed by 2D-STI. The left ventricular function of all patients was quantitatively assessed by 2D-STI. The results of routine echocardiography and left ventricular global strain parameters of the OSAS group, the control group and the OSAS patients with different severity were compared and analyzed. Result: There were no significant differences in the levels of left ventricular ejection fraction (LVEF), left ventricular end diastolic diameter (LVEDd), left ventricular end systolic diameter (LVESd) between the two groups and OSAS patients with different severity (P>0.05). The levels of IVST, LVPW and LVMI in the OSAS group were significantly higher than those in the control group, the levels of end-diastolic interventricular septal thickness (IVS), left ventricular posterior wall thickness (LVPW), left ventricular mass index (LVMI) in the severe OSAS group were significantly higher than those in the mild and moderate OSAS group, and the levels of IVST, LVPW and LVMI in the moderate OSAS group were significantly higher than those in the mild OSAS group, there were significant differences between groups (P<0.05). The levels of GLS, GRS and GCS in the OSAS group were significantly lower than those in the control group (P<0.05). GLS, GRS and GCS levels in the severe OSAS group were significantly lower than those in the mild OSAS group and the moderate OSAS group, while the levels of global longitudinal strain (GLS), global radial strain (GRS) and global circumferential strain (GCS) in the moderate OSAS group were significantly lower than those in the mild OSAS group (P<0.05). Conclusion: The left ventricular systolic function of OSAS patients is obviously impaired. Left ventricular function in OSAS patients can be assessed timely and accurately by two-dimensional speckle tracking imaging. 展开更多
关键词 OBSTRUctIVE sleep APNEA HYPOPNEA syndrome ECHOCARDIOGRAPHY LEFT VENTRICULAR global strain parameters two-dimensional speckle tracking imaging LEFT VENTRICULAR function
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双能量CT非线性融合和噪声优化的虚拟单能量图像技术在喉鳞状细胞癌中的应用 被引量:1
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作者 何长久 刘杰克 +4 位作者 青浩渺 郭玲 胡仕北 周鹏 何乐民 《重庆医科大学学报》 CAS CSCD 北大核心 2024年第2期198-202,共5页
目的:探讨双能量CT线性融合图像(linear blending imaging,LBI)、非线性融合图像(nonlinear blending image,NBI)和噪声优化的虚拟单能量图像(noise-optimized virtual monoenergetic image,VMI+)技术在喉鳞状细胞癌中的应用价值。方法... 目的:探讨双能量CT线性融合图像(linear blending imaging,LBI)、非线性融合图像(nonlinear blending image,NBI)和噪声优化的虚拟单能量图像(noise-optimized virtual monoenergetic image,VMI+)技术在喉鳞状细胞癌中的应用价值。方法:回顾性分析2019年6月至2022年3月61例经病理证实为喉鳞状细胞癌患者的双能量CT资料。双能量图像采用LBI[融合系数为1(80 kV)和0.6(M0.6)]、NBI和VMI+(40 keV、55 keV)技术重建。比较5组图像的客观图像质量[对比噪声比(contrast-tonoise ratio,CNR)、肿瘤CT值、噪声]和主观图像质量(肿瘤边界评分和整体图像质量评分)。结果:40 keV的CNR、肿瘤CT值和肿瘤边界评分均明显高于80 kV、M0.6、NBI和55 keV,差异均有统计学意义(均P<0.05)。NBI的整体图像质量评分明显高于80 kV、M0.6、40 keV和55 keV,差异均有统计学意义(均P<0.05)。NBI的噪声明显低于80 kV、40 keV和55 keV,差异均有统计学意义(均P<0.05)。结论:在喉鳞状细胞癌的双能量CT中,采用VMI+技术(40 keV)能提供更好的CNR、肿瘤CT值和肿瘤边界,采用NBI技术能提供更低的噪声和更好的整体图像质量。 展开更多
关键词 双能量ct 喉鳞状细胞癌 非线性融合图像 噪声优化的虚拟单能量图像
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一种新的术中X线与术前CT图像配准方法 被引量:1
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作者 崔家礼 王杰 +2 位作者 郭曦 陈彧 舒丽霞 《北京生物医学工程》 2024年第2期151-157,186,共8页
目的本研究旨在配准胸主动脉血管内修复术(thoracic endovascular aortic repair,TEVAR)术中X线与术前CT图像,为TEVAR支架植入提供精确安全的导航。然而,现有配准算法存在无法有效弥合投影CT图像生成的数字重建影像(digitally reconstru... 目的本研究旨在配准胸主动脉血管内修复术(thoracic endovascular aortic repair,TEVAR)术中X线与术前CT图像,为TEVAR支架植入提供精确安全的导航。然而,现有配准算法存在无法有效弥合投影CT图像生成的数字重建影像(digitally reconstructed radiography,DRR)与X线图像之间的域间差异和难以获得图像分割标签的问题。因此,需要提出新的方法来改善这一问题。方法本文提出了一种新的配准框架,该框架结合了基于生成对抗网络(generative adversarial network,GAN)的域自适应网络和基于Transformer的配准网络。基于GAN的域自适应网络将X线图像的风格迁移到DRR图像上,使两者在图像风格上更接近。基于Transformer的配准网络采用CNN与跨模态变换器(cross-modality transformer,CMT)相结合的模式,直接配准X线与CT图像,无需进行图像分割。结果本文在208对标定的TEVAR术中X线与CT图像对上对新的配准方法进行了验证。与其他域适应方法相比,本文所采用的CycleGAN网络作为风格转换模块,有效减小了DRR图像与X线图像之间的域间差异。消融实验结果进一步证实,配准网络中的全局局部感知模块(global-local perception module,GLPM)对提高配准精度具有明显作用,而空间缩减(spatial reduction,SR)则有效缩短了配准时间。通过对比现有方法和本文方法在真实患者X线与CT图像对上的配准效果,本文的方法在配准精度和成功率方面均表现出最佳性能。结论本文提出的新的X线与CT图像配准方法有效克服了现有方法存在的域间差异以及难以获得分割标签的问题。 展开更多
关键词 X线图像 ct图像 配准 域自适应 跨模态变换器
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南海神狐海域天然气水合物微观赋存特征的超分辨率CT图像识别 被引量:1
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作者 李承峰 叶旺全 +7 位作者 陈亮 桂斌 郝锡荦 孙建业 张永超 刘乐乐 陈强 郑荣儿 《海洋地质与第四纪地质》 CAS CSCD 北大核心 2024年第3期149-159,共11页
南海神狐海域是我国天然气水合物资源勘探开发的主要目标区之一,2017和2020年先后两次现场试验性开采证实了水合物资源的利用前景。目前,对该地区含水合物储层的精细评价还有待进一步提升,水合物在沉积物孔隙空间中的微观赋存形态是其... 南海神狐海域是我国天然气水合物资源勘探开发的主要目标区之一,2017和2020年先后两次现场试验性开采证实了水合物资源的利用前景。目前,对该地区含水合物储层的精细评价还有待进一步提升,水合物在沉积物孔隙空间中的微观赋存形态是其中的重要影响因素。针对水合物微观赋存形态CT图像表征存在的分辨率不足的问题,建立了一种基于自监督学习的数字图像超分辨率重建算法,实现了CT扫描图像空间分辨率的2倍和4倍提升。在此基础上,对南海神狐海域含水合物沉积物孔隙结构演化规律和水合物微观赋存特征进行了形态表征。由于南海沉积物中存在大量有孔虫壳体,水合物主要占据有孔虫壳体内部空间并堵塞了空隙间的连通喉道,显著降低了沉积物的气、水渗透能力;然而,水合物未能全部占据整个孔隙空间,仍然会有少量的气体和水残留,气体则主要分布于水合物颗粒内部,而水则主要分布在水合物颗粒表面,上述实验结果对地震、测井等现场勘探数据解释具有一定的指导意义。 展开更多
关键词 天然气水合物储层 微观赋存特征 超分辨率重建 ct图像
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CT灌注成像参数对急性脑梗死侧支循环的评估价值及与术后近期预后的相关性 被引量:3
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作者 时建文 杨忠泽 刘森 《中国CT和MRI杂志》 2024年第2期42-44,共3页
目的探讨CT灌注成像(CTPI)参数对急性脑梗死(ACI)侧支循环的评估价值及与术后近期预后的相关性。方法选取我院2022年1月-2023年2月收治的106例ACI患者,以数字血管造影(DSA)作为诊断“金标准”,将其分有侧支循环组(46例)与无侧支循环组(6... 目的探讨CT灌注成像(CTPI)参数对急性脑梗死(ACI)侧支循环的评估价值及与术后近期预后的相关性。方法选取我院2022年1月-2023年2月收治的106例ACI患者,以数字血管造影(DSA)作为诊断“金标准”,将其分有侧支循环组(46例)与无侧支循环组(60例)。两组患者均进行CTPI检查,对比两组受试者CTPI参数[脑血容量(CBV)、脑血流量(CBF)、平均通过时间(MTT)及达峰时间(TTP)],采用受试者工作特征(ROC)曲线分析CTPI参数对ACI侧支循环的预测价值;比较CTPI参数评估急性缺血性脑梗死侧支循环与DSA检查的一致性;采用Pearson相关性分析ACI患者的CTPI参数与美国国立卫生研究院卒中量表(NIHSS)、改良Ranking量表(mRS)评分的相关性。结果有侧支循环组CBV、CBF均高于无侧支循环组(P<0.05),MTT、TTP均低于无侧支循环组(P<0.05)。ROC曲线分析显示,CBV、CBF、MTT、TTP及联合检测对ACI侧支循环均有预测效能(P<0.05),其AUC分别为0.793、0.705、0.841、0.669、0.879,单独检测中MTT效能最高,但仍低于联合检测效能。CTPI参数联合检查对ACI侧支循环的诊断灵敏性为84.78%、特异性为90.00%、准确率为87.74%、阳性预测值为86.67%、阴性预测值为88.52%、Kappa值为0.750。有侧支循环组NIHSS、mRS评分均低于无侧支循环组(P<0.05);Pearson相关分析发现,CBV、CBF与NIHSS、mRS评分呈负相关(P<0.05),MTT、TTP与NIHSS、mRS评分呈正相关(P<0.05)。结论ACI有侧支循环患者的CBV、CBF均较无侧支循环患者高,MTT、TTP均较无侧支循环患者低,CTPI参数用于评估ACI侧支循环具有较高的诊断效能,且有侧支循环患者近期预后较好,同时CBV、CBF、MTT、TTP与ACI患者近期预后均存在相关性,可通过检测CBV、CBF、MTT、TTP预测患者近期预后。 展开更多
关键词 ct灌注成像 急性脑梗死 侧支循环 评估价值 近期预后 相关性
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CT-MRI同体位图像融合在高级别脑胶质瘤放射治疗靶区勾画中应用 被引量:1
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作者 金龙 杨振 +2 位作者 张鑫 刘晓斌 缪星宇 《生物医学工程与临床》 CAS 2024年第1期35-41,共7页
目的探讨同体位MRI图像(MRIsim)与CT模拟定位图像融合在高级别脑胶质瘤放射治疗靶区勾画中的临床应用价值。方法选择20例脑胶质瘤术后放射治疗患者,其中男性13例,女性7例;年龄39~69岁,平均年龄45.5岁;全部为单发病变;均已行全切或不全... 目的探讨同体位MRI图像(MRIsim)与CT模拟定位图像融合在高级别脑胶质瘤放射治疗靶区勾画中的临床应用价值。方法选择20例脑胶质瘤术后放射治疗患者,其中男性13例,女性7例;年龄39~69岁,平均年龄45.5岁;全部为单发病变;均已行全切或不全切手术,全部经病理组织诊断证实;世界卫生组织(WHO)分级Ⅲ级6例,Ⅳ级14例。将每例患者的同体位MRIsim、常规MRI影像(MRIconv)分别与CT模拟定位图像融合。运用Dice相似指数(DSC)和豪斯多夫距离(HD)算法来评价配准的精确度。在CT与MRIsim融合图像(Fusion-CT MRIsim)、CT与MRIconv融合图像(Fusion-CT MRIconv)上分别勾画危及器官(OAR)及靶区[大体肿瘤靶区(GTV)、临床肿瘤靶区(CTV)]。评估两种融合图像(即Fusion-CT MRIsim组和Fusion-CT MRIconv组)OAR勾画体积、GTV、CTV及剂量学差异。结果融合精确度评估:除全脑外,Fusion-CT MRIsim组其余OAR DSC均高于Fusion-CT MRIconv组(P<0.05);Fusion-CT MRIsim组OAR HD小于Fusion-CT MRIconv组(P<0.05)。OAR勾画体积比较:Fusion-CT MRIsim组OAR勾画体积与Fusion-CT MRIconv比较,差异无统计学意义(P>0.05)。靶区:Fusion-CT MRIsim组GTV、CTV小于Fusion-CT MRIconv组[(118.2±8.0)cm^(3)vs(125.3±8.1)cm^(3)、(234.3±12.8)cm^(3)vs(256.0±13.4)cm^(3)],差异有显著统计学意义(均P=0.000)。剂量学比较:Fusion-CT MRIsim组D_(max)-PTV、D_(mean)-PTV与Fusion-CT MRIconv组[(6432.9±23.0)cGy vs(6430.4±25.2)cGy、(6159.0±13.7)cGy vs(6166.2±17.3)cGy]比较,差异无统计学意义(P>0.05)。结论CT-MRI同体位融合图像配准精确度高,可降低全脑平均剂量(D_(mean))及缩小GTV及CTV,是高级别脑胶质瘤术后精确放射治疗值得广泛应用的临床方法。 展开更多
关键词 ct-MRI同体位融合 高级别胶质瘤 放射治疗靶区 靶区勾画
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^(99m)TcO4-SPECT/CT甲状腺核素显像联合超声及TSH对甲状腺结节性质的诊断价值 被引量:1
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作者 王静 吴龙云 +5 位作者 郝宏毅 尹彩君 杨勇 倪效波 张荣 王雪霁 《宁夏医学杂志》 CAS 2024年第3期206-209,F0002,共5页
目的通过高锝酸钠-单光子发射计算机断层显像/电子计算机X射线断层扫描技术(^(99m)TcO4-SPECT/CT)核素显像提供甲状腺结节功能状态、结节解剖特点以及超声检查联合血清促甲状腺激素(TSH)水平进一步鉴别诊断甲状腺结节的良恶性,客观评价... 目的通过高锝酸钠-单光子发射计算机断层显像/电子计算机X射线断层扫描技术(^(99m)TcO4-SPECT/CT)核素显像提供甲状腺结节功能状态、结节解剖特点以及超声检查联合血清促甲状腺激素(TSH)水平进一步鉴别诊断甲状腺结节的良恶性,客观评价甲状腺结节的良恶性情况,对甲状腺结节的良恶性做出早期诊断。方法对因甲状腺结节同时行^(99m)TcO4-SPECT/CT甲状腺核素显像、甲状腺B超及TSH水平检查的患者共80例(92个结节)进行回顾性分析,对比不同方法及联合检查对甲状腺结节的诊断效能。结果92个结节中良性74个,恶性18个;^(99m)TcO4-SPECT/CT甲状腺显像与超声检查比较灵敏度(77.8%)高,特异度(70.2%)及准确度(71.7%)低,假阳性率(29.7%)高,假阴性率(22.2%)低,两者之间灵敏度、特异度、准确度、假阳性率、假阴性率差异均具有统计学意义(P<0.05);两者准确度比较差异无统计学意义(P>0.05)。^(99)mTcO4-SPECT/CT甲状腺显像与超声检查比较灵敏度高,特异性及准确度低,假阳性率高,假阴性率低,两者之间灵敏度、特异度、准确度、假阳性率、假阴性率差异均具有统计学意义(P<0.05);两者准确度比较差异无统计学意义(P>0.05);^(99m)TcO4-SPECT/CT甲状腺显像与超声检查联合较单独核素、单独超声检查灵敏度(88.9%)、特异度(87.8%)、准确度(81.5%)高,假阳性率(12.1%)、假阴性率(11.1%)低;联合检查与单独核素特异度、准确度、假阳性率比较差异有统计学意义(P<0.05),灵敏度与假阴性率比较差异无统计学意义(P>0.05);联合检查与单独超声灵敏度、准确度、假阴性率比较差异有统计学意义(P<0.05);特异度与假阳性率比较差异无统计学意义(P>0.05)。结论超声可以作为甲状腺结节的首选检查方法,其特异性高,但灵敏度低。^(99m)TcO4-SPECT/CT甲状腺显像在提供功能和代谢信息的同时,能提供解剖信息;而血清TSH水平则可为甲状腺结节的良恶性鉴别提供重要的参考依据,尤其对于核素冷结节且超声实性结节的患者,更应参考其TSH水平,将三者结合起来判断甲状腺结节的性质,为临床提供恰当的治疗方案,这具有重要意义。 展开更多
关键词 ^(99m)TcO4-SPEct/ct甲状腺核素显像 超声 血清促甲状腺激素 甲状腺结节
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颅脑CT灌注成像及磁共振成像在脑梗死患者中的应用 被引量:4
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作者 荆梅 顾欣欣 《中国实用神经疾病杂志》 2024年第1期43-47,共5页
目的分析颅脑CT灌注成像及磁共振成像对脑梗死患者的诊断价值。方法选取2022-03—2023-05在江苏省中西医结合医院就诊的80例疑似脑梗死患者为研究对象,对比分析GE Revolution CT颅脑灌注成像、磁共振成像及联合检查的敏感性、特异性、... 目的分析颅脑CT灌注成像及磁共振成像对脑梗死患者的诊断价值。方法选取2022-03—2023-05在江苏省中西医结合医院就诊的80例疑似脑梗死患者为研究对象,对比分析GE Revolution CT颅脑灌注成像、磁共振成像及联合检查的敏感性、特异性、准确性,制作3种影像学检查的受试者工作特征(ROC)曲线。结果根据患者病情和临床综合诊断确诊,80例疑似脑梗死患者中脑梗死阳性69例(86.25%),脑梗死阴性11例(13.75%)。3种影像学检查方法的灵敏度、准确率比较,从高到低依次为联合检查、GE Revolution CT颅脑灌注成像检查、磁共振成像检查,差异有统计学意义(P<0.05)。GE Revolution CT颅脑灌注成像检查、磁共振成像检查、联合检查诊断脑梗死的ROC曲线下面积(AUC)分别为0.8109、0.7688、0.8682。结论GE Revolution CT颅脑灌注成像与磁共振成像检查的联合应用,有利于提高脑梗死患者诊断的灵敏度、准确率及AUC水平。 展开更多
关键词 脑梗死 GE Revolution ct 颅脑灌注成像 磁共振成像 灵敏度 准确率
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GE256排冠状动脉CT血管成像中常规呼吸训练与特殊呼吸训练对质控影响的探讨 被引量:1
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作者 李艳艳 黄慧敏 +1 位作者 龙淼淼 刘铁 《影像技术》 CAS 2024年第4期4-8,共5页
目的:研究GE256排Revolution冠状动脉CT血管成像(coronary computed tomography angiography,CCTA)中患者常规训练呼吸与特殊训练呼吸对心率、图像质量和辐射剂量的影响。方法:应用前瞻性心电门控技术扫描,结合冠状动脉追踪冻结技术(SSF... 目的:研究GE256排Revolution冠状动脉CT血管成像(coronary computed tomography angiography,CCTA)中患者常规训练呼吸与特殊训练呼吸对心率、图像质量和辐射剂量的影响。方法:应用前瞻性心电门控技术扫描,结合冠状动脉追踪冻结技术(SSF)行CCTA检查。共纳入108例患者,分为两组,A组54例患者采取特殊训练呼吸训练方式,B组54例患者行常规训练呼吸,对两组的心率、图像质量、辐射剂量进行统计学分析。结果:A组患者心率慢于B组(P<0.05,t=2.14);A组患者的3支冠状动脉主干(右冠状动脉,左前降支,左回旋支)图像质量显著优于B组(Fisher's exact P=0.010);两组之间的辐射剂量差异无统计学意义(P>0.05)。结论:在GE256排Revolution CCTA检查中,特殊呼吸训练在提高CCTA图像质量方面具有重要价值。 展开更多
关键词 冠状动脉ct血管成像(CctA) 呼吸训练 图像质量 心率 辐射剂量
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采用MSCT灌注成像检查评估周围型非小细胞肺癌分化程度的可行性分析 被引量:1
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作者 江叶 汪祝莎 +1 位作者 孙韬 何洪林 《中国CT和MRI杂志》 2024年第5期77-78,共2页
目的分析多层螺旋CT(MSCT)灌注成像检查评估周围型非小细胞肺癌(NSCLC)分化程度的可行性。方法选取本院2017年7月至2018年10月本院收治确诊的52例周围型NSCLC患者作为研究对象,比较不同分化级别患者的MSCT灌注成像参数;分析灌注参数与... 目的分析多层螺旋CT(MSCT)灌注成像检查评估周围型非小细胞肺癌(NSCLC)分化程度的可行性。方法选取本院2017年7月至2018年10月本院收治确诊的52例周围型NSCLC患者作为研究对象,比较不同分化级别患者的MSCT灌注成像参数;分析灌注参数与分化程度的相关性。结果高分化、中分化周围型NSCLC患者BF、BV、PS、MTT及PH数值均高于低分化周围型NSCLC,以高分化周围型NSCLC的BF、BV、PS、MTT及PH数值最高。各个灌注参数值,其中高分化、中分化周围型NSCLC的BF、PH与低分化周围型NSCLC比较差异显著(P<0.05),三者BV、PS及MTT数值比较,均为明显差异(P>0.05)。周围型NSCLC患者灌注参数BF、PH与其分化程度成负相关,且相关性显著(P<0.05)。结论MSCT灌注成像检查可有效反映周围型NSCLC的分化程度,其灌注参数中BF、PH对评估其分化程度有一定帮助,与周围型NSCLC分化程度具有一定相关性。 展开更多
关键词 多层螺旋ct 灌注成像 周围型非小细胞肺癌 分化程度
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基于投影误差优化网络的碳/碳材料CT稀疏角度重建方法
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作者 金珂 陈博 +4 位作者 金虎 曾天辰 周星明 徐林 孙跃文 《同位素》 CAS 2024年第4期332-340,共9页
在采用^(60)Co作为射线源的碳/碳复合材料的计算机断层扫描(CT)中,降低采样角度数量可以显著缩短检测时间,提升检测效率。然而常规的解析重建算法,稀疏角度的重建图像中包含大量的噪声和伪影,干扰图像中缺陷的检出,影响检测系统在快速... 在采用^(60)Co作为射线源的碳/碳复合材料的计算机断层扫描(CT)中,降低采样角度数量可以显著缩短检测时间,提升检测效率。然而常规的解析重建算法,稀疏角度的重建图像中包含大量的噪声和伪影,干扰图像中缺陷的检出,影响检测系统在快速检测条件下对被检构件的质量评价。本研究提出了一种基于投影误差优化神经网络的稀疏角度CT图像重建方法,采用未训练的编码-解码卷积神经网络优化重建图像的投影误差,结合图像的总变分先验,采用自适应动量估计(ADAM)算法进行优化。与传统的深度学习重建算法相比,该方法无需训练样本集,具备更强的泛化能力和鲁棒性。CT检测实验结果表明,该方法相比于传统的解析和重建算法,重建图像质量大幅提升,在保留被检测构件细节信息的同时,显著抑制了重建图像中的伪影与噪声。 展开更多
关键词 碳/碳复合材料 ^(60)Co ct检测 深度学习 稀疏角度重建
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