Assessment of Regional Left Ventricular Myocardial Function in Rats after Acute Occlusion of Left Anterior Descending Artery by Two-dimensional Speckle Tracking Imaging

This study evaluated the change in regional left ventricular myocardial function in rats following acute occlusion of the left anterior descending coronary artery （LAD） by using two-dimensional speckle tracking imaging （2D-STI）. Sixty Wistar rats were randomly divided into two groups, a myocardial infarction （MI） group, in which 50 rats were subjected to LAD occlusion for 30–45 min, and a sham-operated （SHAM） group that contained 10 rats serving as control. Echo-cardiography was performed at baseline and 1, 4 and 8 week（s） after the operation. High frequency two-dimensional images of left ventricular short axis at papillary muscle level were recorded. Peak systolic radial strain （PRS） and circumferential strain （PCS） were measured in the mid-ventricle in short-axis view by using EchoPAC workstation. Left ventricular internal diameter at diastole （LVIDd） and systole （LVIDs）, fractional shortening （FS）, ejection fraction （EF） and left ventricular mass （LVM） were measured by anatomical M-model echocardiography. Infarct size was measured using triphenyl tetrazolium chloride （TTC） staining 1 week and 8 weeks after the operation. Fibrosis of left ventricu-lar myocardium was displayed using Van Gieson staining 1 week after the infarction. In terms of the TTC staining results, the left ventricle fell into three categories： infarcted, peri-infarcted and remote myocardial regions. Compared with those at baseline and in the SHAM group, （1） PRS and PCS in the infarcted, peri-infarcted and remote myocardial regions were significantly decreased in the MI group within 1 week after the operation （P〈0.05） and the low levels lasted 8 weeks; （2） Compared with those at baseline, LVIDd, LVIDs, FS, EF and LVM in the MI group showed no significant dif-ference 1 week after the operation （P〉0.05）. However, LVIDd, LVIDs and LVM were increased sig-nificantly 4 and 8 weeks after the operation （P〈0.05）, and FS and EF were decreased substantially （P〈0.05）. Van Gieson staining showed that fibrosis developed in all the three myocardial regions to varying degrees. It is concluded that 2D-STI is non-invasive and can be used to assess regional func-tion of myocardium with different blood supply in rats following acute occlusion of the LAD, and can be used as a sensitive and reliable means to follow up the process of left ventricular remodeling.

Assessment of Myocardial Perfusion and Systolic Function in Patients with Coronary Artery Disease after Coronary Artery Bypass Surgery by Myocardial Contrast Echocardiography and Two-dimensional Strain Echocardiography

The clinically applied value of myocardial perfusion and systolic function in patients with coronary artery disease after coronary artery bypass surgery using real-time myocardial contrast echocardiography （RT-MCE） combined with two-dimensional strain echocardiography was assessed. Twenty patients underwent intravenous RT-MCE by intravenous injections of SonoVue before and after coronary artery bypass surgery. Two-dimensional images were recorded from the left ventricular four-chamber view, two-chamber view and the apical view before, and two weeks and three months after coronary artery bypass surgery, and the peak systolic longitudinal strain was measured. The results showed that myocardial perfusion was significantly increased after coronary artery bypass surgery in about 71.6% segments. In the group that myocardial perfusion was improved, the peak systolic longitu- dinal strain three months after bypass surgery was significantly higher than that before operation [（-15.78±5.91）% vs （-10.45±8.31）%, P〈0.05]. However, the parameters did not change in the group without myocardial perfusion improvement [（-10.33±6.53）% vs （-9.41±6.09）%, P〉0.05]. It was concluded that whether or not the improvement of myocardial perfusion can mirror the recovery trend of regional systolic function, two-dimensional strain echocardiography can observe dynamic change of regional systolic function. The combination of myocardial perfusion with two-dimensional strain echocardiography can more accurately assess the curative effectiveness of coronary artery bypass surgery.

GREEN FUNCTION ON TWO-PHASE SATURATED MEDIUM BY CONCENTRATED FORCE IN TWO-DIMENSIONAL DISPLACEMENT FIELD

The Green function on two-phase saturated medium by concentrated force has a broad and important use In seismology, seismic engineering, soil mechanics, geophysics, dynamic foundation theory and so on. According to the Green function on two-phase saturated medium by concentrated force in three-dimentional displacement field obtained by Ding Bo-yang et al., it gives out the Green function in two-dimensional displacement field by infinite integral method along x(3)-direction derived by De Hoop and Manolis. The method adopted in the thesis is simpler. The result will be simplified to the boundary element method of dynamic problem.

Green's functions of two-dimensional piezoelectric quasicrystal in half-space and bimaterials

In this paper,we obtain Green’s functions of two-dimensional(2D)piezoelectric quasicrystal(PQC)in half-space and bimaterials.Based on the elastic theory of QCs,the Stroh formalism is used to derive the general solutions of displacements and stresses.Then,we obtain the analytical solutions of half-space and bimaterial Green’s functions.Besides,the interfacial Green’s function for bimaterials is also obtained in the analytical form.Before numerical studies,a comparative study is carried out to validate the present solutions.Typical numerical examples are performed to investigate the effects of multi-physics loadings such as the line force,the line dislocation,the line charge,and the phason line force.As a result,the coupling effect among the phonon field,the phason field,and the electric field is prominent,and the butterfly-shaped contours are characteristic in 2D PQCs.In addition,the changes of material parameters cause variations in physical quantities to a certain degree.

Band gaps structure and semi-Dirac point of two-dimensional function photonic crystals

Two-dimensional function photonic crystals, in which the dielectric constants of medium columns are the functions of space coordinates , are proposed and studied numerically. The band gaps structures of the photonic crystals for TE and TM waves are different from the two-dimensional conventional photonic crystals. Some absolute band gaps and semiDirac points are found. When the medium column radius and the function form of the dielectric constant are modulated, the numbers, width, and position of band gaps are changed, and the semi-Dirac point can either occur or disappear. Therefore,the special band gaps structures and semi-Dirac points can be achieved through the modulation on the two-dimensional function photonic crystals. The results will provide a new design method of optical devices based on the two-dimensional function photonic crystals.

Comment on “Band gaps structure and semi-Dirac point of two-dimensional function photonic crystals” by Si-Qi Zhang et al.

Recently, Zhang et al. （Chin. Phys. B 26 024208 （2017）） investigated the band gap structures and semi-Dirac point of two-dimensional function photonic crystals, and the equations for the plane wave expansion method were induced to obtain the band structures. That report shows the band diagrams with the effects of function coefficient k and medium column ra under TE and TM waves. The proposed results look correct at first glance, but the authors made some mistakes in their report. Thus, the calculated results in their paper are incorrect. According to our calculations, the errors in their report are corrected, and the correct band structures also are presented in this paper.

Static response of functionally graded multilayered two-dimensional quasicrystal plates with mixed boundary conditions

The unusual properties of quasicrystals(QCs)have attracted tremendous attention from researchers.In this paper,a semi-analytical solution is presented for the static response of a functionally graded(FG)multilayered two-dimensional(2 D)decagonal QC rectangular plate with mixed boundary conditions.Based on the elastic theory of FG 2 D QCs,the state-space method is used to derive the state equations composed of partial differential along the thickness direction.Besides,the Fourier series expansion and the differential quadrature technique are utilized to simulate the simply supported boundary conditions and the mixed boundary conditions,respectively.Then,the propagator matrix which connects the field variables at the upper interface to those at the lower interface of any homogeneous layer can be derived based on the state equations.Combined with the interface continuity condition,the static response can be obtained by imposing the sinusoidal load on the top surfaces of laminates.Finally,the numerical examples are presented to verify the effectiveness of this method,and the results are very useful for the design and understanding of the characterization of FG QC materials in their applications to multilayered systems.

Value of myocardial function in children with Kawasaki disease by two-dimensional and three-dimensional ultrasound speckle tracking

Objective:To investigate the value of two-dimensional ultrasound speckle tracking(2D-STI)and three-dimensional ultrasound speckle tracking(3D-STI)in evaluating myocardial function in children with Kawasaki disease.Methods 92 children with Kawasaki disease admitted to our hospital from February 2017 to February 2019 were retrospectively analyzed.50 children who underwent 3D-STI examination were taken as observation group and 42 children who underwent 2D-STI examination were taken as control group.The left ventricular systolic function index,storage time and analysis time of the image,the diameter of coronary artery,the strain difference of left ventricular basal segment,middle segment,apical segment and whole segment were observed.Results The levels of left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(LVESV),left ventricular myocardial mass(LVMI)in the observation group were higher than those in the control group(P<0.05),but there was no statistical difference in left ventricular ejection fraction(LVEF)between the two groups(P>0.05).The storage time and analysis time of the image in the observation group were significantly lower than those in the control group(P<0.05).The left coronary artery(LCA)and right coronary artery(RCA)in the observation group were higher than those in the control group(P<0.05).There was no statistical difference between left anterior descending(LAD)in the two groups(P>0.05).The longitudinal peak systolic strain(LS),circumferential peak systolic strain(CS)and radial peak systolic strain(RS)in the observation group were higher than those in the control group(P<0.05).The global longitudinal peak strain(GLS),global circumferential peak strain(GCS)and global radial peak strain(GRS)in the observation group were higher than those in the control group(P<0.05).LS and CS in the middle segment of the observation group were higher than those in the control group(P<0.05).Conclusions Compared with 2D-STI,3D-STI can objectively and accurately reflect the myocardial function of children with Kawasaki disease.

Evaluation of the Effect of Sigmoid-Shaped Interventricular Septum on Left Ventricular Systolic Function in Patients with Essential Hypertension by Two-Dimensional Speckle Tracking Echocardiography

Objective: To evaluate left ventricular regional and global systolic function by measuring left ventricular longitudinal strain (LS) in hypertensive patients with sigmoid-shaped interventricular septum (SIS) by two-dimensional speckle tracking (2D-STE);in order to explore whether the sigmoid-shaped interventricular septum affects the left ventricular systolic function in patients with hypertension. Methods: Routine echocardiographic parameters were measured in 30 hypertensive patients with SIS (SIS group) and 30 hypertensive patients without SIS (non-SIS group). The left ventricular segments and global LS were measured by 2D-STE, and the two sets of parameters were compared. Results: The value of the thickness of the basal segment of the interventricular septum (IVSBT), the thickness of the middle segment of the interventricular septum (IVSMT) and the ratio of the basal segment of the ventricular septum to the middle segment of the interventricular septum (IVSBT/IVSMT) in SIS group was higher than that in non-SIS group. However, the value of left ventricular outflow tract diameter (LVOTD) in SIS group was lower than that in non-SIS group. There was a significant difference between the two groups (all P Conclusion: SIS affects left ventricular regional systolic function of patients with hypertension. 2D-STE can early evaluate left ventricular longitudinal systolic function in hypertensive patients with SIS.

Value of two-dimensional speckle tracking imaging in quantitative assessment of left ventricular function in patients with OSAS

Objective: To research the clinical application of two-dimensional speckle tracking imaging (2D-STI) in quantitative assessment of left ventricular function in patients with obstructive sleep apnea-hypopnea syndrome (OSAS). Method: From July 2016 to December 2018, 86 patients with OSAS were selected as OSAS group. According to sleep apnea hypopnea index (AHI), they were divided into mild OSAS group (24 cases), moderate OSAS group (29 cases) and severe OSAS group (33 cases). Another 50 healthy volunteers who underwent physical examination in our hospital during the same period were selected as the control group. The left ventricular function of all patients was quantitatively assessed by 2D-STI. The left ventricular function of all patients was quantitatively assessed by 2D-STI. The results of routine echocardiography and left ventricular global strain parameters of the OSAS group, the control group and the OSAS patients with different severity were compared and analyzed. Result: There were no significant differences in the levels of left ventricular ejection fraction (LVEF), left ventricular end diastolic diameter (LVEDd), left ventricular end systolic diameter (LVESd) between the two groups and OSAS patients with different severity (P>0.05). The levels of IVST, LVPW and LVMI in the OSAS group were significantly higher than those in the control group, the levels of end-diastolic interventricular septal thickness (IVS), left ventricular posterior wall thickness (LVPW), left ventricular mass index (LVMI) in the severe OSAS group were significantly higher than those in the mild and moderate OSAS group, and the levels of IVST, LVPW and LVMI in the moderate OSAS group were significantly higher than those in the mild OSAS group, there were significant differences between groups (P<0.05). The levels of GLS, GRS and GCS in the OSAS group were significantly lower than those in the control group (P<0.05). GLS, GRS and GCS levels in the severe OSAS group were significantly lower than those in the mild OSAS group and the moderate OSAS group, while the levels of global longitudinal strain (GLS), global radial strain (GRS) and global circumferential strain (GCS) in the moderate OSAS group were significantly lower than those in the mild OSAS group (P<0.05). Conclusion: The left ventricular systolic function of OSAS patients is obviously impaired. Left ventricular function in OSAS patients can be assessed timely and accurately by two-dimensional speckle tracking imaging.

Rational and Periodic Wave Solutions of Two-Dimensional Boussinesq Equation

Two new exact, rational and periodic wave solutions are derived for the two-dimensional Boussinesq equation. For the first solution it is obtained by performing an appropriate limiting procedure on the soliton solutions obtained by Hirota bilinear method. The second one in terms of Riemann theta function is explicitly presented by virtue of Hirota bilinear method and its asymptotic property is also analyzed in detail. Moreover, it is of interest to note that classical soliton solutions can be reduced from the periodic wave solutions.

Two-dimensional Boron Nitride for Electronics and Energy Applications

Two-dimensional(2D)boron nitride(BN),the so-called“white graphene,”has demonstrated a great potential in various fields,particularly in electronics and energy,by utilizing its wide bandgap(~5.5 eV),superior thermal stability,high thermal conductance,chemical inertness,and outstanding dielectric properties.However,to further optimize the performances from the view of structure-property relationship,the determinative factors such as crystallite sizes,layer thickness,dispersibility,and surface functionalities should be precisely controlled and adjusted.Therefore,in this review,the synthesis and functionalization methods including“top-down”and“bottom-up”strategies,and non-covalent and covalent modifications for 2D BN are systematically classified and discussed at first,thus catering for the requirements of versatile applications.Then,the progresses of 2D BN applied in the fields of microelectronics such as fieldeffect transistors and dielectric capacitors,energy domains such as thermal energy management and conversion,and batteries and supercapacitors are summarized to highlight the importance of 2D BN.Notably,these contents not only contain the state-of-the-art 2D BN composites,but also bring the current novel design of 2D BN-based microelectronic units.Finally,the challenges and perspectives are proposed to better broaden the scope of this material.Therefore,this review will pave an all-around way for understanding,utilizing,and applying 2D BN in future electronics and energy applications.

Establishing a protein expression profile database for the normal human pituitary gland using two-dimensional high-performance liquid chromatography combined with LTQ-Orbitrap mass spectrometry

In this study, we selected adult normal pituitary gland tissues from six patients during operations for pituitary microadenomas via the transsphenoidal approach for extended normal pituitary tissue resection around the tumor, and analyzed the protein expression of human normal pituitary using two-dimensional high-performance liquid chromatography combined with LTQ-Orbitrap mass spectrometry proteomics technology. The ten most highly expressed proteins in normal human pituitary were： alpha 3 type VI collagen isoform 5 precursor （abundance among tall pituitary proteins 1.30%）, fibrinogen beta chain preproprotein （0.99%）, vimentin （0.73%）, prolactin （0.69%）, ATP synthase, H~ transporting and mitochondrial F1 complex beta subunit precursor （0.52%）, keratin I （0.49%）, growth hormone （0.45%）, carbonic anhydrase I （0.40%）, heat shock protein 90 kDa I （0.31%）, and annexin V （0.30%）. Based on the biological function classifications of these proteins, the top three categories by content were neuroendocrine proteins （abundance among all pituitary proteins, 40.1%）, catalytic and metabolic proteins （28.3%）, and cell signal transduction proteins （9.8%）. Based on cell positioning classification, the top three categories were cell organelle （24.5%） membrane （20.8%）, and cytoplasm （13.0%）. Based on biological process classification, the top three categories of proteins are involved in physiological processes （42.9%）, cellular processes （40.4%）, and regulation of biological processes （9.1%）. Our experimental findings indicate that a protein expression profile database of normal human pituitary can be precisely and efficiently established by proteomics technology.

Pseudohalide induced tunable electronic and excitonic properties in two-dimensional single-layer perovskite for photovoltaics and photoelectronic applications

Two-dimensional(2D) layered organic-inorganic hybrid perovskites have attracted much more attention for some applications than their three-dimensional(3D) perovskite counterparts due to their promising thermal and moisture stabilities.In particular, the 2D perovskite devices have shown better promise for optoelectronic applications.However, tunability of optoelectronic properties is often demanded to improve the device performance.Herein, we adopt a newly method to tune the electronic properties of 2D perovskite by introducing pseudohalide into the structure.In this work, we designed a pseudohalidesubstituted 2D perovskite by substituting the out-of-plane halide with pseudohalide and studied the electronic and excitonic properties of 2D-BA2MX4 and 2D-BA2MX2Ps2(M=Ge^(2+), Sn^(2+), and Pb^(2+);X=I;Ps=NCO, NCS, OCN, SCN, Se CN).We revealed the dependence of electronic properties including band gaps, composition of band edges, bonding characteristics, work functions, effective masses, and exciton binding energies on different pseudohalides substituted in 2D perovskite.Our results indicate that the substitution of pseudohalide in 2D perovskites is energetically favorable and can significantly affect the bonding characteristics as well as the CBM and VBM that often play major role in determining their performance in optoelectronic devices.It is expected that the pseudohalide substitution will be helpful in developing more advanced optoelectronic device based on 2D perovskite by optimizing band alignment and promoting charge extraction.

Experimental and theoretical studies on two-dimensional vanadium carbide hybrid nanomaterials derived from V_(4)AlC_(3) as excellent catalyst for MgH_(2)

Hydrogen is considered one of the most ideal future energy carriers.The safe storage and convenient transportation of hydrogen are key factors for the utilization of hydrogen energy.In the current investigation,two-dimensional vanadium carbide(VC) was prepared by an etching method using V_(4)AlC_(3) as a precursor and then employed to enhance the hydrogen storage properties of MgH_(2).The studied results indicate that VC-doped MgH_(2) can absorb hydrogen at room temperature and release hydrogen at 170℃. Moreover,it absorbs 5.0 wt.%of H_(2) within 9.8 min at 100℃ and desorbs 5.0 wt.% of H_(2) within 3.2 min at 300℃.The dehydrogenation apparent activation energy of VC-doped MgH_(2) is 89.3 ± 2.8 kJ/mol,which is far lower than that of additive-free MgH_(2)(138.5 ± 2.4 kJ/mol),respectively.Ab-initio simulations showed that VC can stretch Mg-H bonds and make the Mg-H bonds easier to break,which is responsible for the decrease of dehydrogenation temperature and conducive to accelerating the diffusion rate of hydrogen atoms,thus,the hydrogen storage properties of MgH_(2) are remarkable improved through addition of VC.

Image encryption technique based on new two-dimensional fractional-order discrete chaotic map and Menezes–Vanstone elliptic curve cryptosystem

We propose a new fractional two-dimensional triangle function combination discrete chaotic map(2D-TFCDM)with the discrete fractional difference.Moreover,the chaos behaviors of the proposed map are observed and the bifurcation diagrams,the largest Lyapunov exponent plot,and the phase portraits are derived,respectively.Finally,with the secret keys generated by Menezes-Vanstone elliptic curve cryptosystem,we apply the discrete fractional map into color image encryption.After that,the image encryption algorithm is analyzed in four aspects and the result indicates that the proposed algorithm is more superior than the other algorithms.

A simplified two-dimensional boundary element method with arbitrary uniform mean flow

To reduce computational costs, an improved form of the frequency domain boundary element method（BEM） is proposed for two-dimensional radiation and propagation acoustic problems in a subsonic uniform flow with arbitrary orientation. The boundary integral equation（BIE） representation solves the two-dimensional convected Helmholtz equation（CHE） and its fundamental solution, which must satisfy a new Sommerfeld radiation condition（SRC） in the physical space. In order to facilitate conventional formulations, the variables of the advanced form are expressed only in terms of the acoustic pressure as well as its normal and tangential derivatives, and their multiplication operators are based on the convected Green＇s kernel and its modified derivative. The proposed approach significantly reduces the CPU times of classical computational codes for modeling acoustic domains with arbitrary mean flow. It is validated by a comparison with the analytical solutions for the sound radiation problems of monopole,dipole and quadrupole sources in the presence of a subsonic uniform flow with arbitrary orientation.

Two-dimensional titanium carbonitride MXene as a highly efficient electrocatalyst for hydrogen evolution reaction

In this paper,we report,for the first time,on the electrochemical catalytic activity of 2D titanium carbonitride MXene for hydrogen evolution reaction(HER).According to our study,2D titanium carbonitride exhibited much higher electrocatalytic activity than its carbide analogues,achieving an onset overpotential of 53 mV and Tafel slope of 86 mV dec^(-1),superior to the titanium carbide with onset overpotential of 649 mV and Tafel slope of 303 mV dec^(-1).The obtained onset overpotential for 2D titanium carbonitride is lower than those of all the reported transition metal carbides MXene catalysts without additives,so far.Density functional theory calculations were conducted to further understand the electrochemical performance.The calculation results show that a greater number of occupied states are active for Ti_(3)CNO_(2),revealing free energy for the adsorption of atomic hydrogen closer to 0 than that of Ti_(3)C_(2)O_(2).Both experimental and calculation studies demonstrate the excellent electrocatalytic behavior of titanium carbonitride.The investigation of 2D titanium carbonitride opens up a promising paradigm for the conscious design of high-performance non-precious metal catalyst for hydrogen generation.

Two-Dimensional Organometallic TM3–C12S12 Monolayers for Electrocatalytic Reduction of CO2

Organometallic nanosheets are a versatile platform for design of efficient electrocatalyst materials due to their high surface area and uniform dispersion of metal active sites.In this paper,we systematically investigate the electrocatalytic performance of the first transition metal series TM3–C12S12 monolayers on CO2 using spin-polarized density functional theory.The calculations show that M3–C12S12 exhibits excellent catalytic activity and selectivity in the catalytic reduction in CO2.The main reduction products of Sc,Ti,and Cr are CH4.V,Mn,Fe and Zn mainly produce HCOOH,and Co produces HCHO,while CO is the main product for Ni and Cu.For Sc,Ti,and Cr,the overpotentials are>0.7 V,while for V,Mn,Fe,Co,Ni,Cu,Zn,the overpotentials are very low and range from 0.27 to 0.47 V.Therefore,our results indicate that many of the M3–C12S12 monolayers are expected to be excellent and efficient CO2 reduction catalysts.

General decay of energy to a nonlinear viscoelastic two-dimensional beam

A viscoelastic beam in a two-dimensional space is considered with nonlinear tension. A boundary feedback is applied at the right boundary of the beam to suppress the undesirable vibration. The well-posedness of the problem is established. With the multiplier method, a uniform decay result is proven.