This article obtains some theoretical results on the number of clear two-factor interaction components and weak minimum aberration in an sm-pIVdesign, by considering the number of not clear two-factor interaction comp...This article obtains some theoretical results on the number of clear two-factor interaction components and weak minimum aberration in an sm-pIVdesign, by considering the number of not clear two-factor interaction components of the design.展开更多
Clear effects criterion is one of the important rules for selecting optimal fractional factorial designs,and it has become an active research issue in recent years.Tang et al.derived upper and lower bounds on the maxi...Clear effects criterion is one of the important rules for selecting optimal fractional factorial designs,and it has become an active research issue in recent years.Tang et al.derived upper and lower bounds on the maximum number of clear two-factor interactions(2fi's) in 2n-(n-k) fractional factorial designs of resolutions III and IV by constructing a 2n-(n-k) design for given k,which are only restricted for the symmetrical case.This paper proposes and studies the clear effects problem for the asymmetrical case.It improves the construction method of Tang et al.for 2n-(n-k) designs with resolution III and derives the upper and lower bounds on the maximum number of clear two-factor interaction components(2fic's) in 4m2n designs with resolutions III and IV.The lower bounds are achieved by constructing specific designs.Comparisons show that the number of clear 2fic's in the resulting design attains its maximum number in many cases,which reveals that the construction methods are satisfactory when they are used to construct 4m2n designs under the clear effects criterion.展开更多
In this study,umami taste intensity(UTI)and umami taste components in chicken breast(CB)and chickenspices blends were characterized using sensory and instrumental analysis.Our main objective was to assess the aroma-um...In this study,umami taste intensity(UTI)and umami taste components in chicken breast(CB)and chickenspices blends were characterized using sensory and instrumental analysis.Our main objective was to assess the aroma-umami taste interactions in different food matrices and reconcile the aroma-taste perception to assist future product development.The impact of key aroma,including vegetable-note"2-pentylfuran",meaty"methional",green"hexanal",and spicy-note-estragole and caryophyllene"on UTI was evaluated in monosodium glutamate and chicken extract.We found that spices significantly decreased UTI and umami taste components in CB.Interestingly,the perceptually similar odorants and tastants exhibited the potential to enhance UTI in food matrices.Methional was able to increase the UTI,whereas spicy and green-note components could reduce the UTI significantly.This information would be valuable to food engineers and formulators in aroma selection to control the UTI perceived by consumers,thus,improving the quality and acceptability of the chicken products.展开更多
Despite many efforts into the study of fluids interaction in low salinity water flooding, they are not probing the basics of transport phenomena between the involved phases. This work is aimed to bring new understandi...Despite many efforts into the study of fluids interaction in low salinity water flooding, they are not probing the basics of transport phenomena between the involved phases. This work is aimed to bring new understanding of fluid-fluid interaction during low salinity water flooding through a series of organized experiments in which a crude oil sample with known properties was kept in contact with different brine solutions of various ionic strengths. Measuring brine pH, conductivity and crude oil viscosity and density for a period of 45 days illustrates the strong effect of the contact time and ionic strength on the dissociation of polar components and physical properties of the crude oil and brine. Besides, the interfacial tension(IFT) measurements show that the interfacial interactions are affected by several competitive interfacial processes. By decreasing the ionic strength of the brine, the solubility of naphthenic acids in the aqueous solution increases, and hence,the conductivity and the pH of the aqueous phase decrease. To verify this important finding, UV-Vis spectroscopy and 'H NMR analysis were also performed on aged brine samples. Notably, there is an ionic strength of brine in which the lowest IFT is observed, while the other physical properties are remained relatively unchanged.展开更多
The IFTs(Interfacial tension)of petroleum carboxylate/alkaline/HPAM(Hydrolyzed polyacrylamide)flooding system with Daing crude oil and the effects of petroleum carboxylate and alkaline on viscoaity of HPAM solution we...The IFTs(Interfacial tension)of petroleum carboxylate/alkaline/HPAM(Hydrolyzed polyacrylamide)flooding system with Daing crude oil and the effects of petroleum carboxylate and alkaline on viscoaity of HPAM solution were studied.There exists remarkable synergism between HPAM and petroleum carboxylate,and the introduction of HPAM into petroleum carboxylate/alka- line system leads the lowering of IFTs against Daqing crude oil,The introduction of petroleum carboxylate into solution of HPAM also leads the decreasing of viscosity,but the extent of viscosity decreasing is much lower than that caused by inorganic salts such as NaCl and CaCl_2.展开更多
Some antitumor activities of component (E), extracted from the root of Fagopynum Cymosum (Trev) Meisn (FCTM), have recently been discovered in vivo and in vitro. The component E (CE)'s pattern of action with tumor...Some antitumor activities of component (E), extracted from the root of Fagopynum Cymosum (Trev) Meisn (FCTM), have recently been discovered in vivo and in vitro. The component E (CE)'s pattern of action with tumor cellular DNA at the molecular pharmacological level was investigated by macromolecular synthesis experiment (MSE) and human DNA interaction system established in our laboratory. The experiments demonstrated that, in vitro, the agent could markedly inhibit the incorporation of 3H-TdR into the cellular DNA, and the IC50 in P388 leukemia cell and in SGC-7901 cell was 17.86 μg/ml and 110.4 μg/ml, respectively. The agent, at mg/ml level, could produce an intercalation reversion pattern with DNA within a short time (2 hours). But when the interval was prolonged for over 4 hours, the action changed to intercalation irreversible pattern. According to these observations, the authors infer that CE interacts with DNA in two ways - directly and indirectly. The indirect action, especially in low concentrations, probably plays the major role. The authors have also compared the interaction of CE with those of components (CB3 and CD1), extracted from FCTM by the same methods, and found that CE is the most active agent against the DNA of cancer cells among the extracts from FCTM.展开更多
The present study deals with dynamic analysis of arch concrete dams,taking rotational components of earthquakes into account.A modified methodology was used to evaluate the rotational components of the earthquake.The ...The present study deals with dynamic analysis of arch concrete dams,taking rotational components of earthquakes into account.A modified methodology was used to evaluate the rotational components of the earthquake.The translational components of the earthquake have been used in to obtain the rotational components of the earthquake,based on the intersecting isotropic elastic wave propagation.Two rotational components of Taft,Tabas and San-Fernando earthquakes are evaluated based on the translational components of the earthquakes and considering frequency dependencies of incident angle and wave velocity.Finally,dynamic analyses of Morrow Point Dam are presented to evaluate the effects of combined translational and rotational components on the seismic response of the dam.Various conditions of reservoirs,including full and empty state,are considered in the analyses.Fluid–structure interaction was completely taken into account.It was realized that incorporating rotational components increased the maximum compressive and tensile stresses in both empty and full reservoir analyses.Distribution of maximum tensile stresses is very sensitive to the rotational components of the earthquake.Also,it can be concluded that the segregated effect of the rocking component on the response of concrete dams is more effective than the sole effect of the torsional component.展开更多
The Kaikoura earthquake on November 14,2016 is one of the largest and most complex earthquakes in New Zealand since 1947.Despite the fact that it has ruptured about 12 separate faults,triggered 2132 aftershocks within...The Kaikoura earthquake on November 14,2016 is one of the largest and most complex earthquakes in New Zealand since 1947.Despite the fact that it has ruptured about 12 separate faults,triggered 2132 aftershocks within one week of the mainshock and induced considerable stress changes,few studies have been conducted to comprensively investigate the characteristics.The current study examines the horizontal and vertical displacements as well as the stress and gravity changes,aftershock distributions and also find out whether these changes affect the surrounding regions along the complex fault systems.The study covers the entire area affected by the Kaikoura event,which includes the northern part of the South Island and the southern part of the North Island.The dislocation theory was employed to evaluate the coseismic slip model on the multiple faults.The displacement results revealed that the maximum horizontal displacement is about 6 m and the vertical about 2 m,which are reasonably consistent with earlier study findings.Besides,the stress and gravity changes are quite complicated and inhomogeneous as evidenced by our coseismic model,demonstrating the complexity of the Kaikoura earthquake as well.Almost all the aftershocks are distributed in places where the stress and gravity change are found to be significant.In order to investigate the stability of our stress change models,we applied different friction coefficients and receiver fault parameters.The results justify the friction coefficient(μ=0.4)and the receiver fault parameters(230°,70°,150°)are suitable to define good stress change estimates.According to the stress change results at 15 km depth,the northern parts of the mainshock region,Hundalee fault,Humps fault and Jordan thrust areas together with the Wellington area are closer to failure and situated in a seismic risk zone.The multidimensional analysis adopted in this paper is helpful for making decisions and applications of stress and gravity change models in assessing seismic hazards.展开更多
In this paper,we consider the statistical inference problems for the fixed effect and variance component functions in the two-way classification random effects model with skewnormal errors.Firstly,the exact test stati...In this paper,we consider the statistical inference problems for the fixed effect and variance component functions in the two-way classification random effects model with skewnormal errors.Firstly,the exact test statistic for the fixed effect is constructed.Secondly,using the Bootstrap approach and generalized approach,the one-sided hypothesis testing and interval estimation problems for the single variance component,the sum and ratio of variance components are discussed respectively.Further,the Monte Carlo simulation results indicate that the exact test statistic performs well in the one-sided hypothesis testing problem for the fixed effect.And the Bootstrap approach is better than the generalized approach in the one-sided hypothesis testing problems for variance component functions in most cases.Finally,the above approaches are applied to the real data examples of the consumer price index and value-added index of three industries to verify their rationality and effectiveness.展开更多
According to the hierarchical characteristics of monthly rainfall in different regions, the paper takes the geographical factors and seasonal factors into the hierarchical linear model as the level effect. Through clu...According to the hierarchical characteristics of monthly rainfall in different regions, the paper takes the geographical factors and seasonal factors into the hierarchical linear model as the level effect. Through clustering methods we select two more representative regional meteorological data. We establish three-layer model by transforming the interactive structure date into nested structure data. According the model theory we perform the corresponding model calculations, optimization and analysis, accordingly to interpret the level effects, and residual test. The results show that most of the difference in Monthly Rainfall was respectively explained by Variables (Meteorological factors, seasonal effects, geographic effects) in different levels.展开更多
Although genome-wide association studies are widely used to mine genes for quantitative traits,the effects to be estimated are confounded,and the methodologies for detecting interactions are imperfect.To address these...Although genome-wide association studies are widely used to mine genes for quantitative traits,the effects to be estimated are confounded,and the methodologies for detecting interactions are imperfect.To address these issues,the mixed model proposed here first estimates the genotypic effects for AA,Aa,and aa,and the genotypic polygenic background replaces additive and dominance polygenic backgrounds.Then,the estimated genotypic effects are partitioned into additive and dominance effects using a one-way analysis of variance model.This strategy was further expanded to cover QTN-by-environment interactions(QEIs)and QTN-by-QTN interactions(QQIs)using the same mixed-model framework.Thus,a three-variance-component mixed model was integrated with our multi-locus random-SNP-effect mixed linear model(mrMLM)method to establish a new methodological framework,3VmrMLM,that detects all types of loci and estimates their effects.In Monte Carlo studies,3VmrMLM correctly detected all types of loci and almost unbiasedly estimated their effects,with high powers and accuracies and a low false positive rate.In re-analyses of 10 traits in 1439 rice hybrids,detection of 269 known genes,45 known gene-by-environment interactions,and 20 known gene-by-gene interactions strongly validated 3VmrMLM.Further analyses of known genes showed more small(67.49%),minor-allele-frequency(35.52%),and pleiotropic(30.54%)genes,with higher repeatability across datasets(54.36%)and more dominance loci.In addition,a heteroscedasticity mixed model in multiple environments and dimension reduction methods in quite a number of environments were developed to detect QEIs,and variable selection under a polygenic background was proposed for QQI detection.This study provides a new approach for revealing the genetic architecture of quantitative traits.展开更多
基金supported by the China Postdoctoral Science Foundation (20060390169)the Philosophy and Social Science Foundation of China (07CTJ002)+1 种基金the National Natural Science Foundation of China (10671099)Program for New Century Excellent Talents in University(NCET-08-0909)
文摘This article obtains some theoretical results on the number of clear two-factor interaction components and weak minimum aberration in an sm-pIVdesign, by considering the number of not clear two-factor interaction components of the design.
基金supported by the National Natural Science Foundation of China (Grant Nos. 10571093,10671099and 10771123)the Research Foundation for Doctor Programme (Grant No. 20050055038)+1 种基金the NaturalScience Foundation of Shandong Province of China (Grant No. Q2007A05)Zhang’s research was also supportedby the Visiting Scholar Program at Chern Institute of Mathematics
文摘Clear effects criterion is one of the important rules for selecting optimal fractional factorial designs,and it has become an active research issue in recent years.Tang et al.derived upper and lower bounds on the maximum number of clear two-factor interactions(2fi's) in 2n-(n-k) fractional factorial designs of resolutions III and IV by constructing a 2n-(n-k) design for given k,which are only restricted for the symmetrical case.This paper proposes and studies the clear effects problem for the asymmetrical case.It improves the construction method of Tang et al.for 2n-(n-k) designs with resolution III and derives the upper and lower bounds on the maximum number of clear two-factor interaction components(2fic's) in 4m2n designs with resolutions III and IV.The lower bounds are achieved by constructing specific designs.Comparisons show that the number of clear 2fic's in the resulting design attains its maximum number in many cases,which reveals that the construction methods are satisfactory when they are used to construct 4m2n designs under the clear effects criterion.
基金supported by the National Natural Science Foundation of China (31622042)。
文摘In this study,umami taste intensity(UTI)and umami taste components in chicken breast(CB)and chickenspices blends were characterized using sensory and instrumental analysis.Our main objective was to assess the aroma-umami taste interactions in different food matrices and reconcile the aroma-taste perception to assist future product development.The impact of key aroma,including vegetable-note"2-pentylfuran",meaty"methional",green"hexanal",and spicy-note-estragole and caryophyllene"on UTI was evaluated in monosodium glutamate and chicken extract.We found that spices significantly decreased UTI and umami taste components in CB.Interestingly,the perceptually similar odorants and tastants exhibited the potential to enhance UTI in food matrices.Methional was able to increase the UTI,whereas spicy and green-note components could reduce the UTI significantly.This information would be valuable to food engineers and formulators in aroma selection to control the UTI perceived by consumers,thus,improving the quality and acceptability of the chicken products.
基金supported by Iranian Offshore Oil Company (IOOC)
文摘Despite many efforts into the study of fluids interaction in low salinity water flooding, they are not probing the basics of transport phenomena between the involved phases. This work is aimed to bring new understanding of fluid-fluid interaction during low salinity water flooding through a series of organized experiments in which a crude oil sample with known properties was kept in contact with different brine solutions of various ionic strengths. Measuring brine pH, conductivity and crude oil viscosity and density for a period of 45 days illustrates the strong effect of the contact time and ionic strength on the dissociation of polar components and physical properties of the crude oil and brine. Besides, the interfacial tension(IFT) measurements show that the interfacial interactions are affected by several competitive interfacial processes. By decreasing the ionic strength of the brine, the solubility of naphthenic acids in the aqueous solution increases, and hence,the conductivity and the pH of the aqueous phase decrease. To verify this important finding, UV-Vis spectroscopy and 'H NMR analysis were also performed on aged brine samples. Notably, there is an ionic strength of brine in which the lowest IFT is observed, while the other physical properties are remained relatively unchanged.
文摘The IFTs(Interfacial tension)of petroleum carboxylate/alkaline/HPAM(Hydrolyzed polyacrylamide)flooding system with Daing crude oil and the effects of petroleum carboxylate and alkaline on viscoaity of HPAM solution were studied.There exists remarkable synergism between HPAM and petroleum carboxylate,and the introduction of HPAM into petroleum carboxylate/alka- line system leads the lowering of IFTs against Daqing crude oil,The introduction of petroleum carboxylate into solution of HPAM also leads the decreasing of viscosity,but the extent of viscosity decreasing is much lower than that caused by inorganic salts such as NaCl and CaCl_2.
文摘Some antitumor activities of component (E), extracted from the root of Fagopynum Cymosum (Trev) Meisn (FCTM), have recently been discovered in vivo and in vitro. The component E (CE)'s pattern of action with tumor cellular DNA at the molecular pharmacological level was investigated by macromolecular synthesis experiment (MSE) and human DNA interaction system established in our laboratory. The experiments demonstrated that, in vitro, the agent could markedly inhibit the incorporation of 3H-TdR into the cellular DNA, and the IC50 in P388 leukemia cell and in SGC-7901 cell was 17.86 μg/ml and 110.4 μg/ml, respectively. The agent, at mg/ml level, could produce an intercalation reversion pattern with DNA within a short time (2 hours). But when the interval was prolonged for over 4 hours, the action changed to intercalation irreversible pattern. According to these observations, the authors infer that CE interacts with DNA in two ways - directly and indirectly. The indirect action, especially in low concentrations, probably plays the major role. The authors have also compared the interaction of CE with those of components (CB3 and CD1), extracted from FCTM by the same methods, and found that CE is the most active agent against the DNA of cancer cells among the extracts from FCTM.
文摘The present study deals with dynamic analysis of arch concrete dams,taking rotational components of earthquakes into account.A modified methodology was used to evaluate the rotational components of the earthquake.The translational components of the earthquake have been used in to obtain the rotational components of the earthquake,based on the intersecting isotropic elastic wave propagation.Two rotational components of Taft,Tabas and San-Fernando earthquakes are evaluated based on the translational components of the earthquakes and considering frequency dependencies of incident angle and wave velocity.Finally,dynamic analyses of Morrow Point Dam are presented to evaluate the effects of combined translational and rotational components on the seismic response of the dam.Various conditions of reservoirs,including full and empty state,are considered in the analyses.Fluid–structure interaction was completely taken into account.It was realized that incorporating rotational components increased the maximum compressive and tensile stresses in both empty and full reservoir analyses.Distribution of maximum tensile stresses is very sensitive to the rotational components of the earthquake.Also,it can be concluded that the segregated effect of the rocking component on the response of concrete dams is more effective than the sole effect of the torsional component.
基金financially supported by the National Key Research Program of China“Collaborative Precision Positioning Project”(No.2016YFB0501900)the National Natural Science Foundation of China(No.41374032)。
文摘The Kaikoura earthquake on November 14,2016 is one of the largest and most complex earthquakes in New Zealand since 1947.Despite the fact that it has ruptured about 12 separate faults,triggered 2132 aftershocks within one week of the mainshock and induced considerable stress changes,few studies have been conducted to comprensively investigate the characteristics.The current study examines the horizontal and vertical displacements as well as the stress and gravity changes,aftershock distributions and also find out whether these changes affect the surrounding regions along the complex fault systems.The study covers the entire area affected by the Kaikoura event,which includes the northern part of the South Island and the southern part of the North Island.The dislocation theory was employed to evaluate the coseismic slip model on the multiple faults.The displacement results revealed that the maximum horizontal displacement is about 6 m and the vertical about 2 m,which are reasonably consistent with earlier study findings.Besides,the stress and gravity changes are quite complicated and inhomogeneous as evidenced by our coseismic model,demonstrating the complexity of the Kaikoura earthquake as well.Almost all the aftershocks are distributed in places where the stress and gravity change are found to be significant.In order to investigate the stability of our stress change models,we applied different friction coefficients and receiver fault parameters.The results justify the friction coefficient(μ=0.4)and the receiver fault parameters(230°,70°,150°)are suitable to define good stress change estimates.According to the stress change results at 15 km depth,the northern parts of the mainshock region,Hundalee fault,Humps fault and Jordan thrust areas together with the Wellington area are closer to failure and situated in a seismic risk zone.The multidimensional analysis adopted in this paper is helpful for making decisions and applications of stress and gravity change models in assessing seismic hazards.
基金supported by National Social Science Foundation of China(21BTJ068)。
文摘In this paper,we consider the statistical inference problems for the fixed effect and variance component functions in the two-way classification random effects model with skewnormal errors.Firstly,the exact test statistic for the fixed effect is constructed.Secondly,using the Bootstrap approach and generalized approach,the one-sided hypothesis testing and interval estimation problems for the single variance component,the sum and ratio of variance components are discussed respectively.Further,the Monte Carlo simulation results indicate that the exact test statistic performs well in the one-sided hypothesis testing problem for the fixed effect.And the Bootstrap approach is better than the generalized approach in the one-sided hypothesis testing problems for variance component functions in most cases.Finally,the above approaches are applied to the real data examples of the consumer price index and value-added index of three industries to verify their rationality and effectiveness.
文摘According to the hierarchical characteristics of monthly rainfall in different regions, the paper takes the geographical factors and seasonal factors into the hierarchical linear model as the level effect. Through clustering methods we select two more representative regional meteorological data. We establish three-layer model by transforming the interactive structure date into nested structure data. According the model theory we perform the corresponding model calculations, optimization and analysis, accordingly to interpret the level effects, and residual test. The results show that most of the difference in Monthly Rainfall was respectively explained by Variables (Meteorological factors, seasonal effects, geographic effects) in different levels.
基金supported by the National Natural Science Foundation of China(32070557 and 31871242)the Fundamental Research Funds for the Central Universities(2662020ZKPY017)+1 种基金the Huazhong Agricultural University Scientific&Technological Self-Innovation Foundation(2014RC020)the State Key Laboratory of Cotton Biology Open Fund(CB2021B01).
文摘Although genome-wide association studies are widely used to mine genes for quantitative traits,the effects to be estimated are confounded,and the methodologies for detecting interactions are imperfect.To address these issues,the mixed model proposed here first estimates the genotypic effects for AA,Aa,and aa,and the genotypic polygenic background replaces additive and dominance polygenic backgrounds.Then,the estimated genotypic effects are partitioned into additive and dominance effects using a one-way analysis of variance model.This strategy was further expanded to cover QTN-by-environment interactions(QEIs)and QTN-by-QTN interactions(QQIs)using the same mixed-model framework.Thus,a three-variance-component mixed model was integrated with our multi-locus random-SNP-effect mixed linear model(mrMLM)method to establish a new methodological framework,3VmrMLM,that detects all types of loci and estimates their effects.In Monte Carlo studies,3VmrMLM correctly detected all types of loci and almost unbiasedly estimated their effects,with high powers and accuracies and a low false positive rate.In re-analyses of 10 traits in 1439 rice hybrids,detection of 269 known genes,45 known gene-by-environment interactions,and 20 known gene-by-gene interactions strongly validated 3VmrMLM.Further analyses of known genes showed more small(67.49%),minor-allele-frequency(35.52%),and pleiotropic(30.54%)genes,with higher repeatability across datasets(54.36%)and more dominance loci.In addition,a heteroscedasticity mixed model in multiple environments and dimension reduction methods in quite a number of environments were developed to detect QEIs,and variable selection under a polygenic background was proposed for QQI detection.This study provides a new approach for revealing the genetic architecture of quantitative traits.