Dyslipidemia is a disorder where abnormally lipid concentrations circulate in the bloodstream. The disorder is common in type 2 diabetics (T2D) and is linked with T2D comorbidities, particularly cardiovascular disease...Dyslipidemia is a disorder where abnormally lipid concentrations circulate in the bloodstream. The disorder is common in type 2 diabetics (T2D) and is linked with T2D comorbidities, particularly cardiovascular disease. Dyslipidemia in T2D is typically characterized by elevated plasma triglyceride and low high-density lipoprotein cholesterol (HDL-C) levels. There is a significant gap in the literature regarding dyslipidemia in rural parts of Africa, where lipid profiles may not be captured through routine surveillance. This study aimed to characterize the prevalence and demo-graphic profile of dyslipidemia in T2D in the rural community of Ganadougou, Mali. We performed a cross-sectional study of 104 subjects with T2D in Ganadougou between November 2021 and March 2022. Demographic and lipid profiles were collected through cross-sectional surveys and serological analyses. The overall prevalence of dyslipidemia in T2D patients was 87.5% (91/104), which did not differ by sex (P = .368). High low-density lipoprotein cholesterol (LDL-C) was the most common lipid abnormality (78.9%, [82/104]). Dyslipidemia was associated with age and hypertension status (P = .013 and.036, respectively). High total and high LDL-C parameters were significantly associated with hypertension (P = .029 and .006, respectively). In low-resource settings such as rural Mali, there is a critical need to improve infrastructure for routine dyslipidemia screening to guide its prevention and intervention approaches. The high rates of dyslipidemia observed in Gandadougou, consistent with concomitant increases in cardiovascular diseases in Africa suggest that lipid profile assessments should be incorporated into routine medical care for T2D patients in African rural settings.展开更多
In the traditional flow-resistance-differential (FRD) type valve-less piezoelectric pump, the generated outflow and pressure are discontinuous because of the inherent periodicity and fluctuation of the pump. To overco...In the traditional flow-resistance-differential (FRD) type valve-less piezoelectric pump, the generated outflow and pressure are discontinuous because of the inherent periodicity and fluctuation of the pump. To overcome these drawbacks, utilizing the bending vibration of piezoelectric bimorph to drive fluid was conducted. However, our investigation on the current status of this piezoelectric bimorph pump shows that larger driving force and vibration amplitude are required for fluid pumping; the pumping can be realized through the centrifugal force; and the mechanism of fluid pumping is no longer further studied. Based on these cases, the paper designed a piezoelectric-stack pump with variable-cross-section oscillating (VCSO) vibrator by imitating the swing of the caudal-fin of tuna, and the pump is neither the rotating type nor the volumetric type according to the taxonomy. The interaction between the oscillating vibrator and the fluid parcel is firstly analyzed from the viewpoint of momentum conservation, and the analytical expression of pump flow rate is obtained. Then the modal and harmonic response analyses on the vibrator immerged in water are carried out. From the analyses the first two orders resonance frequencies are 832 Hz and 1 939 Hz, respectively, and the peak value of the tip amplitude is 0.6 mm. Laser Doppler vibrometer is used to measure both the frequency and vibration amplitude, and the determined first two orders resonance frequencies are 617 Hz and 1 356 Hz, respectively. The measured tip amplitude reaches to the peak value of 0.3 mm. At last, experimental measurement for the flow rates with different driving frequencies is conducted. The results show that the flow rate can reach 560 mL/min at 1 370 Hz when the pump runs under the backpressure of 30 mm water column. And the flow rate is as much as 560% of that of experiment results carried out by researchers from Brazil. The proposed pump innovates in both theory and taxonomy; in addition, the pump overcomes the drawbacks such as large flow fluctuation and low flow rate in the traditional FRD type pumps, which will help to broaden the application of the valve-less piezoelectric pump.展开更多
Samples were collected continuously and systematically from Beds 2 to 30 of the Meishan D section, and nearly 4,000 foraminiferal specimens were recognized. In total, 72 species （partially including undetermined spec...Samples were collected continuously and systematically from Beds 2 to 30 of the Meishan D section, and nearly 4,000 foraminiferal specimens were recognized. In total, 72 species （partially including undetermined species and conformis species） in 34 genera of foraminifers were identified. Twelve foraminiferal community zones were established from Beds 2 to 27 based on the abundance, dominance, diversity, and equitability of the foraminiferal fauna and a functional morphological analysis of the dominant and characteristic species. The habitat type indicated by each community zone and the sedimentary features were used to determine the paleo-water depths and the relative changes in sea level. We generated curves of both the habitat type and the hydrodynamic conditions, which together indicate the relative changes in the paleo-water depth and the substrate features in the studied area during the Changhsingian. This study discusses the possible relationship between the foraminiferal community zones and the sea-level changes based on a statistical analysis of the foraminiferal community zones.展开更多
The static test of 13 square hollow section(SHS) X-joints with different β and different types of plate reinforcement under in-plane moment in brace was carried out. Experimental test schemes, failure modes of specim...The static test of 13 square hollow section(SHS) X-joints with different β and different types of plate reinforcement under in-plane moment in brace was carried out. Experimental test schemes, failure modes of specimens, moment-vertical displacement curves, moment-deformation of the chord, and strain strength distribution curves were presented. The effect of β and plate reinforcement types on in-plane flexural property of SHS X-joints was studied. Results show that punching shear of chord face disappears, brace material fracture appears and concave and convex deformation of chord decrease when either collar plates or doubler plates were welded on chord face. Moment-vertical displacement curves of all specimens have obvious elastic, elastic-plastic and plastic stages. As β increases, the in-plane flexural ultimate capacity and initial stiffness of joints of the same plate reinforcement type increase, but ductility of joints decreases. With the same β, the in-plane flexural initial stiffness and ultimate capacity of doubler plate reinforced joints, collar plate reinforced joints, and unreinforced joints decrease progressively. Thickness of reinforcement plate has no obvious effect on in-plane flexural initial stiffness and ultimate capacity of joints. As thickness of reinforcement plate increases, the ductility of reinforced X-joints decreases. The concave and convex deformation of every specimen has good symmetry;as β increases, the yield and ultimate deformation of chord decrease.展开更多
In order to realize further stability of a stack-type thermoelectric power generating module (i.e. no electrical connections inside), flexible materials of metal springs and/or rods having restoring forces were instal...In order to realize further stability of a stack-type thermoelectric power generating module (i.e. no electrical connections inside), flexible materials of metal springs and/or rods having restoring forces were installed between lower-temperature-sides of thermoelectric elements. These flexible materials were expected to play three important roles of interpolating different thermal expansions of the module components, enlarging heat removal area and penetration of any media through themselves. Then, a low-boiling-point medium (i.e. NOVEC manufactured by 3M Japan Ltd.) was also applied for a high-speed direct heat removal via its phase change from the lower-temperature-sides of the thermoelectric elements in the proposing stack-type thermoelectric power generating module. No electrical disconnections inside the module were confirmed for more than 9 years of use, indicating further module stability. The power generating density was improved to about 120 mW·m-2 with SUS304 springs having 0.7 mm diameter. Increasing power generating density can be expected in terms of suitable selection of flexible metal with high Vickers hardness, cavities control on the spring surface, more vigorous multiphase flow with adding powders to the medium and optimization of the module configurations according to numerical simulations.展开更多
文摘Dyslipidemia is a disorder where abnormally lipid concentrations circulate in the bloodstream. The disorder is common in type 2 diabetics (T2D) and is linked with T2D comorbidities, particularly cardiovascular disease. Dyslipidemia in T2D is typically characterized by elevated plasma triglyceride and low high-density lipoprotein cholesterol (HDL-C) levels. There is a significant gap in the literature regarding dyslipidemia in rural parts of Africa, where lipid profiles may not be captured through routine surveillance. This study aimed to characterize the prevalence and demo-graphic profile of dyslipidemia in T2D in the rural community of Ganadougou, Mali. We performed a cross-sectional study of 104 subjects with T2D in Ganadougou between November 2021 and March 2022. Demographic and lipid profiles were collected through cross-sectional surveys and serological analyses. The overall prevalence of dyslipidemia in T2D patients was 87.5% (91/104), which did not differ by sex (P = .368). High low-density lipoprotein cholesterol (LDL-C) was the most common lipid abnormality (78.9%, [82/104]). Dyslipidemia was associated with age and hypertension status (P = .013 and.036, respectively). High total and high LDL-C parameters were significantly associated with hypertension (P = .029 and .006, respectively). In low-resource settings such as rural Mali, there is a critical need to improve infrastructure for routine dyslipidemia screening to guide its prevention and intervention approaches. The high rates of dyslipidemia observed in Gandadougou, consistent with concomitant increases in cardiovascular diseases in Africa suggest that lipid profile assessments should be incorporated into routine medical care for T2D patients in African rural settings.
基金supported by National Natural Science Foundation of China (Grant No. 50775109, Grant No. 51075201)Important Project of National Natural Science Foundation of China (Grant No. 50735002)Open Foundation for National Key laboratory of the Numerical Manufacturing Equipment and Technology of China (Grant No. DMETKF2009002)
文摘In the traditional flow-resistance-differential (FRD) type valve-less piezoelectric pump, the generated outflow and pressure are discontinuous because of the inherent periodicity and fluctuation of the pump. To overcome these drawbacks, utilizing the bending vibration of piezoelectric bimorph to drive fluid was conducted. However, our investigation on the current status of this piezoelectric bimorph pump shows that larger driving force and vibration amplitude are required for fluid pumping; the pumping can be realized through the centrifugal force; and the mechanism of fluid pumping is no longer further studied. Based on these cases, the paper designed a piezoelectric-stack pump with variable-cross-section oscillating (VCSO) vibrator by imitating the swing of the caudal-fin of tuna, and the pump is neither the rotating type nor the volumetric type according to the taxonomy. The interaction between the oscillating vibrator and the fluid parcel is firstly analyzed from the viewpoint of momentum conservation, and the analytical expression of pump flow rate is obtained. Then the modal and harmonic response analyses on the vibrator immerged in water are carried out. From the analyses the first two orders resonance frequencies are 832 Hz and 1 939 Hz, respectively, and the peak value of the tip amplitude is 0.6 mm. Laser Doppler vibrometer is used to measure both the frequency and vibration amplitude, and the determined first two orders resonance frequencies are 617 Hz and 1 356 Hz, respectively. The measured tip amplitude reaches to the peak value of 0.3 mm. At last, experimental measurement for the flow rates with different driving frequencies is conducted. The results show that the flow rate can reach 560 mL/min at 1 370 Hz when the pump runs under the backpressure of 30 mm water column. And the flow rate is as much as 560% of that of experiment results carried out by researchers from Brazil. The proposed pump innovates in both theory and taxonomy; in addition, the pump overcomes the drawbacks such as large flow fluctuation and low flow rate in the traditional FRD type pumps, which will help to broaden the application of the valve-less piezoelectric pump.
基金supported by the Foundation of the Geological Survey of China [grant no. 121201004000150021]
文摘Samples were collected continuously and systematically from Beds 2 to 30 of the Meishan D section, and nearly 4,000 foraminiferal specimens were recognized. In total, 72 species （partially including undetermined species and conformis species） in 34 genera of foraminifers were identified. Twelve foraminiferal community zones were established from Beds 2 to 27 based on the abundance, dominance, diversity, and equitability of the foraminiferal fauna and a functional morphological analysis of the dominant and characteristic species. The habitat type indicated by each community zone and the sedimentary features were used to determine the paleo-water depths and the relative changes in sea level. We generated curves of both the habitat type and the hydrodynamic conditions, which together indicate the relative changes in the paleo-water depth and the substrate features in the studied area during the Changhsingian. This study discusses the possible relationship between the foraminiferal community zones and the sea-level changes based on a statistical analysis of the foraminiferal community zones.
基金Projects(51278209 and 51478047) supported by the National Natural Science Foundation of ChinaProject(ZQN-PY110) supported by Promotion Program for Young and Middle-aged Teacher in Science and Technology Research of Huaqiao University,China+1 种基金Project(2014FJ-NCET-ZR03) supported by Program for New Century Excellent Talents in Fujian Province University,ChinaProject(JA13005) supported by Incubation Programme for Excellent Young Science and Technology Talents in Fujian Province Universities,China
文摘The static test of 13 square hollow section(SHS) X-joints with different β and different types of plate reinforcement under in-plane moment in brace was carried out. Experimental test schemes, failure modes of specimens, moment-vertical displacement curves, moment-deformation of the chord, and strain strength distribution curves were presented. The effect of β and plate reinforcement types on in-plane flexural property of SHS X-joints was studied. Results show that punching shear of chord face disappears, brace material fracture appears and concave and convex deformation of chord decrease when either collar plates or doubler plates were welded on chord face. Moment-vertical displacement curves of all specimens have obvious elastic, elastic-plastic and plastic stages. As β increases, the in-plane flexural ultimate capacity and initial stiffness of joints of the same plate reinforcement type increase, but ductility of joints decreases. With the same β, the in-plane flexural initial stiffness and ultimate capacity of doubler plate reinforced joints, collar plate reinforced joints, and unreinforced joints decrease progressively. Thickness of reinforcement plate has no obvious effect on in-plane flexural initial stiffness and ultimate capacity of joints. As thickness of reinforcement plate increases, the ductility of reinforced X-joints decreases. The concave and convex deformation of every specimen has good symmetry;as β increases, the yield and ultimate deformation of chord decrease.
文摘In order to realize further stability of a stack-type thermoelectric power generating module (i.e. no electrical connections inside), flexible materials of metal springs and/or rods having restoring forces were installed between lower-temperature-sides of thermoelectric elements. These flexible materials were expected to play three important roles of interpolating different thermal expansions of the module components, enlarging heat removal area and penetration of any media through themselves. Then, a low-boiling-point medium (i.e. NOVEC manufactured by 3M Japan Ltd.) was also applied for a high-speed direct heat removal via its phase change from the lower-temperature-sides of the thermoelectric elements in the proposing stack-type thermoelectric power generating module. No electrical disconnections inside the module were confirmed for more than 9 years of use, indicating further module stability. The power generating density was improved to about 120 mW·m-2 with SUS304 springs having 0.7 mm diameter. Increasing power generating density can be expected in terms of suitable selection of flexible metal with high Vickers hardness, cavities control on the spring surface, more vigorous multiphase flow with adding powders to the medium and optimization of the module configurations according to numerical simulations.
