Promoting Sickle Cell Trait Awareness and Education: A Typology of Interventions in the United States to Inform Ongoing Efforts to Patients and Providers

Research Background: Sickle cell trait has no treatment or cure and predominantly affects people who are Black, but can affect anyone of any race or ethnicity. While commonly incorrectly considered benign by providers and the public, people with a sickle cell trait experience life-threatening outcomes that are exacerbated by extreme conditions. There is a severe lack of awareness and understanding of sickle cell trait and the associated health complications among sickle cell trait carriers and healthcare providers. Purpose/Aim: Interventions that aim to improve awareness of sickle cell trait differ in approaches and are not well documented in the literature. This typology aims to highlight current efforts to inform targeted interventions that raise awareness through consistent messaging, educate people and providers on sickle cell trait and the related health complications, and support the design and implementation of comprehensive sickle cell trait awareness initiatives. Methods: We conducted a scoping review of United States-based sickle cell trait interventions and performed a content analysis to identify the categories and characteristics of these efforts. We then organized the results into a typology according to established protocols. Results: Among 164 interventions, twenty-five (15%) met the typology inclusion criteria described above and were grouped into categories: Seven of twenty-five interventions were Educational Interventions (28%), three of twenty-five interventions (12%) were Combined Screening and Educational-Based Interventions, eight of twenty-five interventions (32%) were Policy and Guideline-Based Intervention, and six of twenty-five interventions (24%) were Sickle Cell Trait Organization-Led Interventions. Conclusions: There is a lack of consistency in messaging across interventions whether delivered by credible healthcare institutions or national organizations, which can result in lack of education and awareness and confusion around sickle cell trait. Categorizing interventions through a typology allows clarity and informs consistency in messaging, which should be at the forefront of future sickle cell trait efforts.

Typology and Agroecology of Agroecosystems in Vegetation Dynamics in the Ecotones of the Mbam and Inoubou

Agroforestry systems strongly characterize the Cameroonian agrarian landscape. Agroforests are among those structuring the ecotones of Mbam and Inoubou in the Central Cameroon region. Numerous works on agroecosystems of Central and South Cameroon, few have come out contribution of the structure of these traditional systems in the dynamics of the vegetation of these forest-savannah ecotones. The present contribution has the overall objective of demonstrating the structural efficiency of agroforests the dynamics of ecotone vegetation, but also in the conservation of biodiversity. To do this, a participatory analysis was carried out with 56 farmers distributed in the five villages of Makénéné. Botanical inventories supplemented socio-economic household surveys. The data collected was subjected to various analyzes (univariate test, analysis of variance, multivariate test, PCA, CAH). The results reveal that 55.2% of agroforests are less than 15 years old and those with an area greater than 1500 m2 predominate (33%). They are mainly young with generally small surface areas. The horizontal structure reveals that the largest diameter classes are those of [20 - 30 cm[ and [10 - 20 cm[ with a very low rate of basal area. Agroforests with trees over 10 m high are dominant in five villages of Makénéné. Two types of structural profiles characterize the agroforestry flora of the area, namely intensive pluristratified home gardens on savannah and intensive pluristratified agroforests under forest-savannah transition vegetation. Principal Component Analysis (PCA) and Ascending Hierarchical Clustering (HAC) show three Agroforest Clusters each. The PCA distribution reveals that woody biomass (Y) is strongly correlated with tree diameter (DBH) and significantly with height (Cluster 2). The age (AAG) (Cluster 1) of these agroforests, on the other hand, remains independent of the density (DST) of these trees (Cluster 3). The agroforests in the Nyokon, Carrière and Mocksud villages are the most effective in terms of conserving woody diversity while the agroforests of the Kinding ndé and Nyokon villages are more efficient in the reforestation processes. These results could be considered as effective and quantifiable tools for the certification of numerous cash crops such as cocoa and coffee, which will make it possible to valorize this local knowledge in terms of scientific and in the development of various programs and writing of technical notes.

Typology-based Vitality Promotion of Urban Waterfront Public Space in the Three Gorges Reservoir

Revitalization of waterfront-a precious resource of city has gradually become popular worldwide. Cities around the Three Gorges Reservoir grow and proper for the Yangtze River,thus waterfront in these cities has been long ignored or faced with "constructive destruction" with the city development. This paper divided urban waterfront public spaces around the Three Gorges into 3 kinds of spaces,namely point,line and surface,from the perspective of typology,and put forward strategies such as functional renovation,and improvement of spatial scale from the perspectives of land use and traffic,to enhance the vitality of waterfront public space.

The Arithmetic of Natural Language:Toward a typology of numeral systems

Numeral systems in natural languages show astonishing variety,though with very strong unifying tendencies that are increasing as many indigenous numeral systems disappear through language contact and globalization.Most numeral systems make use of a base,typically 10,less commonly 20,followed by a wide range of other possibilities.Higher numerals are formed from primitive lower numerals by applying the processes of addition and multiplication,in many languages also exponentiation;sometimes,however,numerals are formed from a higher numeral,using subtraction or division.Numerous complexities and idiosyncrasies are discussed,as are numeral systems that fall outside this general characterization,such as restricted numeral systems with no internal arithmetic structure,and some New Guinea extended body-part counting systems.

Qualitative Assessment and Typology of the Water Resource Used for the Production of Drinking Water in Duékoué, Western Côte d’Ivoire

The objective of this study was to evaluate the typology of water through physicochemical and bacteriological characterization with the aim of highlighting its vulnerability as a drinking water resource. The methodology adopted was to evaluate the level of pollution by monitoring the spatiotemporal variation of the water pollution indicator levels of Lake Dohou. The sampling frequency is monthly for one year, from November 2017 to October 2018, in order to obtain a fairly representative image of water quality and its seasonal evolution in eight (8) well-defined stations. The parameters were determined using the standard methods defined by the French Association for Standardization (AFNOR). This study shows that the waters are acidic, with an average pH of 5.81 and a low electrical conductivity of between 42.67 ± 4.30 and 59.62 ± 21.84 μS.cm-1. At all stations, seasonal mean water transparencies are low (<1 m). It is also noted that 99.7% of the water samples collected had total nitrogen (TN) levels above the limit of 4 mg.L-1. All of the lake’s waters have non-compliant BOD5 (2.L-1) for raw water intended for the production of drinking water. Sites D6 and D7 have COD/BOD5 ratio greater than 3, which indicates the presence of non-biodegradable organic matter in these areas. Total coliforms, Escherichia coli and Enterococci were present in 100% (28/28) water samples at concentrations ranging from 2300 to 173,000 CFU/100 mL, from 100 to 1650 CFU/100 mL and from 20 to 1140 CFU 1/100 mL respectively. For Salmonella pathogens, they were detected in 50% of the dry season samples and in 100% of the rainy season samples. This almost permanent presence of this pathogenic germ denotes a poor quality of water with reference to this parameter. The presence of total coliform and other microbial contaminants suggests that supplied water is highly contaminated with pathogens and great reservoirs for them. Principal component analysis (PCA) of the physicochemical data set allowed defining three different classes of water on the Dohou Lake. Outside the upstream zone (D6 and D8), water could continue to be used for the production of drinking water.

Relevance of Linguistic Typology to Formal Theory：Minim alist Inquiry and Word Order

This article argues that the theoretical desiderata of Minimalist Program (MP)will actually necessitate, or even force, a high level of sensitivity to cross-linguistic structural variation, at least higher than has been the case in Principles and Parameters Theory. Moreover, this heightened sensitivity to cross-linguistic variation is likely to call into question two fundamental assumptions in Generative Grammar (GG), namely the distinction between competence and performance as well as the objection to the inclusion of performance in linguistic theory. By drawing on word order and, to a lesser extent, case marking (also related ultimately to linearization) for purposes of illustration, the article will explain how GG, as reconfigured in MP, needs Linguistic Typology more than ever, as MP theorists are becoming increasingly aware of the relevance of cross-linguistic variation to their minimalist inquiry. Furthermore, functional motivations or explanations (e.g.performance), typically utilized in LT, are likely to resonate well with the minimalist focus on so-called interface conditions.

Epidemiological Studies on the Relationship between PTSD Symptoms and Circadian Typology and Mental/Sleep Health of Young People Who Suffered a Natural Disaster, Great Hanshin-Awaji Earthquake

This study aims, first, to determine the relationship between Post Traumatic Stress Disorder (PTSD) and current circadian typology and sleep habits of adults who experienced the Great Hanshin-Awaji Earthquake in their childhood in January 1995. An integrated questionnaire was administered to 275 university students (females: 173, males: 93, unknown: 9) aged 19 - 37 (mean age: 21.9 years) in Hyogo Prefecture, Japan. The questionnaire consisted of basic questions about attributes, questions on sleep habits and sleep quality (Monroe’s sleep quality index), the Torsvall-?kerstedt Diurnal Type Scale and the Impact of Event Scale-Revised (IES-R) to obtain PTSD scores. Participants who scored 25 or more in the IES-R were placed in a high-traumatic group (HTG) and those who scored less than 25 were placed in a low-traumatic group (LTG). HTG participants exhibited significantly worse sleep quality than LTG participants (p < 0.001). Although there was no significant difference in sleep latency (p > 0.05), HTG participants woke more frequently during sleep (p < 0.001) and had more difficulty falling asleep (p = 0.001) than LHG participants. Significantly more LTG participants fell asleep easily and slept deeply than HTG participants (p = 0.005, p = 0.011). Only among females, HTG participants were more evening-typed than LTG participants (p = 0.035). These results suggest that people who suffered a disaster in childhood and currently have PTSD have difficulty achieving high sleep quality. Evening-type lifestyles may reinforce the symptoms of PTSD. The study aims, second, to examine the effects of intervention for one month using a leaflet to promote the morning-typed life for persons who suffered natural disaster entitled “Go to bed early, Get up early and Do not forget to have a breakfast for getting three benefits!”. Only one person was over the cutoff point (between 24 and 25) before intervention. This high-traumatic person’s comprehensive sleep health tended to be improved through the intervention (p = 0.052). Such intervention to improve their quality of sleep and promote a morning-typed lifestyle may be an effective way to reduce PTSD symptoms.

The Dynamics of Suspended Particulate Matter in the Oued Nachef(Tafna Basin,Algeria):Typology of Flood Events and Contribution to Sediment Transport

This article focuses on the study of sediment transport during flood events in the Oued Nachef watershed that feeds the Mefrouche dam.To understand the sediment dynamics in this watershed,ANRH data on instantaneous water discharges and the respective concentrations of suspended particulate matter were used.This enabled the selection of some of the largest flood events over a 24-year period in order to establish the log-log relationships between sediment load(concentration and flux)and water discharge.However,the discharge-concentration relationships revealed hysteresis phenomena that enabled a flood typology to be established and classified into seven categories,thus showing very different transfer dynamics in relation to flood events.The results showed that Category 6 floods presenting hysteresis in the form of a figure of eight exported almost 44%of the suspended particulate matter load while representing just 29%of the flow discharge.

Typology and Risk Factors of Public Road Accidents in Kinshasa with Its Two Peripheral Areas (Mongata and Kasangulu) from March to May 2017

Introduction: Road traffic put people at risks and needs health education to avoid accidents and deaths. This article aimed to build up a typology of public road accidents (public road accidents) and risk factors associated with in the provincial city of Kinshasa and its peripheral cities (Kasangulu and Mongata), to identify the profiles of the vehicles and people involved in these public road accidents. Method: We conducted a prospective eco-analytical study on a stratified random sample whose size was determined by the Fischer formula. Results: Overall, from March to May 2017, we witnessed an incidence of public road accidents cases ranging from 139 public road accidents cases in the city province of Kinshasa and its two peripheral areas: road axes of high concentration: Rte Blvd Lumumba-Airport;Rte Poids Lourd-Pont Matete, the axes of medium concentration: Rte N21-IMBU, Rte Blvd 30 juin-socimat;Rte Matadi-Kasangulu toll;Rte Université-Intendance, Rte By Pass-triangle Maman Mobutu-Kintambo (Rte-Matadi)-Toll/lère virage-Triangle Maman Mobutu and those of low concentration were: Rte du tourisme/Mimoza-Mbudi;Rte Matadi-Terrain Siwabanza. Conclusion: In these areas, public road accidents are a real public health problem that deserves sustained attention from all and especially from decision makers. Interventions must concern the HVE accident complex.

Questionnaire and Intervention Study on Effects of Drinking Cows’ Milk at Breakfast on the Circadian Typology and Mental Health of Japanese Infants Aged 1 - 6 Years

This study examines relationship between drinking cows’ milk at breakfast and several mental and physical characteristics (the diurnal type, sleep habits and mental condition as anger, out of control of emotion, irritation and depression) of Japanese small children aged 1 - 6 years old. A questionnaire study and an intervention one were performed in this study. An integrated questionnaire was administered, in July 2014 to 1112 participants attending one of 10 nursery school and 1 kindergarten located in Kochi (33&deg;N, 133&deg;E), Japan, and 582 parents (mostly mothers) which answered it instead of children (rate of answer: 51.9%). Intervention was done to 111 children attending the kindergarten. Seventy six parents answered the questionnaire which was administered 3 months after the intervention days of 21 (rate of answer: 51.9%). There are two contents of intervention, one is the distribution of cows’ milk for 21 days to be drunk at breakfast and another is the distribution of leaflet entitled “Go to bed early! Get up early! and Take nutritionally rich breakfast and cows’ milk!” just before the intervention. Just before the intervention, letter was distributed to 111 parents who were asked for their children to follow the contents of the leaflet and drink the cows’ milk distributed every day for the 21 days. Small children who drink cows’ milk at breakfast more than once per week and take nutritionally rich breakfast more than 4 times per week are more morning-typed than the other three groups in which children fit into one or none of the two issues of taking morning cows’ milk and rich breakfast (p p = 0.004). Also there was positive correlation between the implementation value for the 21 days and the diurnal type score 3 months later (r = 0.301, p = 0.018). Drinking cows’ milk at breakfast seems to be effective for small children to become more morning-typed through two sets of syntheses from tryptophan via serotonin into melatonin in the evening.

An Essay to Searle's Typology of Speech Acts

With knowing how to make sounds with the vibration of vocals,humans are not just intending to make meaningless noi-ses,but also to communicate with each other thus they make 'languages'.For example,if a girl accepts a boy's invitation to a con-cert,she will reply him in a basic way with'I will see you in front of the theatre by 7pm tomorrow!'.After the amazing concert,the girl may express the feeling with'What a wonderful concert!Thank you for inviting me this time! '.Then she wants to invite him for a movie next time,so she asks'Do you want to watch this movie next week with me? '.They may create more simple but significant sentences like these to communicate with each other for the basic requests,invitations or expressions to improve their relationship.The communications in the example are the main topic for my following essay,which is to discuss the basic pragmatic way of people com-municating with each other and the significance of the theory of speech acts profound by an American Philosopher John R.Searle.

Typology of Local Construction Materials from the Adamawa and North-West Regions of Cameroon

This article summarizes the different local construction materials observed in two regions of Cameroon (Adamawa and North-West). These raw materials were mapped and evaluated using various methods of investigation (spatial distribution, estimation of reserves, development of a database compatible with geo-referenced maps). The results obtained show three types of local construction materials (vegetal, pedological and geological) with quantitative estimation or distribution. Vegetal local materials include herbaceous savanna with strong dominance of straw in Adamawa region than the North West region. Pedological local construction materials include lateritic soils (ferruginous or clayey), harplan, sandy clay and sandy clay soil while geological local construction materials include volcanic, plutonic and metamorphic rocks. Many sites of these geological materials are suitable for the rock quarry plant. Adamawa region also contains sedimentary rocks constituted by metamorphic conglomerate and sandstones. Two main types of residential homes are constructed with these local construction materials in these regions of Cameroon. These include huts and houses.

Application of Text Typology Theory in Aviation English Translation

In the late 1970s,with the development of functionalist theory,an introduction of the specific functional text-type model theory was put forward.A communicative purpose of translation was proposed,changing the consideration of lower linguistic levels.This paper expounds on the theory and the translation strategies of Text Typology and discusses the translation of the principles of fighter aerial combat.The author applies the method of communicative translation and takes some specific translation methods to analyze avionics aerial combat.

Innovation:A state-of-the-art review and typology

Innovation is often an object of study in economics and management.However,the social and behavioral aspects of innovation acceptance are as important as the economics of product development.A significant portion of the literature considers innovation as a change in the way social actions are conducted,entailing a wide range of social,economic,behavioral,and institutional changes.Various approaches have given rise to the need for a typology.Sundbo(1998)divided innovation into three groups depending on the aspects of the phenomenon:theory of entrepreneurship,technological and social aspects,and strategic aspects.Adopting Sundbo's conceptual framework,this study supplemented and developed it based on recent literature that appeared after 1998.Moreover,this study added new directions at the second level of decomposition and the relationships between different aspects of innovation.In particular,this study analyzed phenomena such as open innovation,agile innovation,and“helix”models.Thus,this study developed a novel typology of innovation that expands the theoretical knowledge in this field.Based on these findings,this study proposed promising areas for future innovation studies.

A Method of Evaluation Efficacy of Cosmetics Exfoliator and Its Application

Measuring the tanning skin can provide a scientific method to evaluate the efficacy of cosmetics exfoliator.Dihydroxyacetone(DHA,5.0%(w/w))was used to stain the inner forearms cuticle of subjects.The skin surface L*and b*were determined,then ITA and its recovery rate were calculated to evaluate the exfoliating efficacy of cosmetics.The results showed that no significant(P≥0.05)differences were observed for L*,b*and ITA on different skin surface of unstained subjects.After staining with DHA,no adverse reaction was found in the stained areas,and the changes of L*,b*and ITA on different skin surface were consistent(P≥0.05).Two different cosmetics were used continuously to exfoliate the skin in different areas.After treatment for 7 days,the corresponding areas of skin L*,b*and ITA had significant(P<0.05)improvement in comparison with negative control area.But there were differences in the evaluation results of the exfoliation efficacy using these three parameters.The recovery rate of ITA of two samples improved significantly(P<0.05)than the negative control area.The work indicated that using 5.0%DHA for skin browning and measuring the skin surface color change by ITA recovery rate can accurately and sensitively assess the skin cuticle renewal rate difference.This method can be used as one of the effective way to evaluate the efficacy of cosmetics exfoliation.

Contribution of Garcinia kola to the Productivity and Economic Profitability of the Community Agricultural Area of Kedougou: Financial and Comparative Analysis of Production Factors

Inland fishing predominates in the Kedougou region, which has no coastline. This type of fishing does not yet meet the local population’s demand for fish products. In response to this concern, a Community Agricultural Estate housing an integrated fish farm was set up in the commune of Bandafassi, in the village of Itato. Since its creation, this production unit has been faced with the problem of sourcing high-quality, low-cost, monosex male Oreochromis niloticus fry. In order to overcome this constraint, the present research focuses on the contribution of Garcinia kola to the productivity and economic profitability of the Itato farm. The aim of the research is to assess fish production in the experimental set-up and the production costs of tilapia in a controlled environment. The comparative study of the various production factors shows disparities only in the input factor, where scenarios 2 and 3 use additional products. These are 17-α-methytestosterone for scenario 2 and Garcinia kola for scenario 3. These products significantly interfere with fish production, with a fairly high mortality rate for scenario 2 (25% for two production cycles/ cohort2 (B5, B6, B7 and B8) treated with 17-α-methytestosterone). As for scenarios 1 and 3, mortalities are 5% with or without recourse to additional products (G. kola). In addition, average fish production for the three (03) scenarios is estimated at 28687.5 kg/2 cycles. It varies from one scenario to another, i.e. 30937.5 kg/2 cycles for scenarios 1 and 3 and 24187.5 kg/2 cycles for scenario 2. It is therefore higher in scenarios 1 and 3 than in scenario 2. This difference is due to the fairly large losses of individuals in scenario 2. Furthermore, the analysis of the profit and loss accounts for tilapia production varies from one scenario to another depending on the type of farm: 476 Franc CFA for scenario 1, 610 Franc CFA for scenario 2 and 472 Franc CFA for scenario 3 (F CFA = franc of the French Colonies of Africa). The Average operating income for all the fish farming units is 34,726,142 Franc CFA. The highest (41,638,075 Franc CFA) and lowest (29,281,075 Franc CFA) ERs were observed in scenarios 3 and 2 respectively. It was 33,259,275 Franc CFA for scenario 1. The difference between the NERs of the three scenarios is more or less significant in terms of results. The operating result (OR) is positive in all 3 scenarios in our study. However, the scenario 3 system generates a higher rate of return (the ratio between an income and the capital employed to obtain that income) (74%) than that generated by the scenario 1 system (69%). As for the scenario 2 system, it generates a lower financial return than the two previous systems (67%). Above all, this work made it possible to construct an approach that would make it possible to answer such a question by relying successively on various methods: a typology, according to the production factors involved in the operation of the Community Agricultural Estate fish farm.

Aspects of anaphora in Chinese and in some Germanic,Romance,and Slavic languages,the‘syntactic'versus‘pragmatic'language typology,and neo-Gricean pragmatics

In this article,two types of anaphora—(i)null subjects and(ii)long-distance reflexivisation— will be briefly compared and contrasted between Chinese and some Germanic,Romance,and Slavic languages,showing how they are different typologically.Following Huang(2000a,2013a),utilising intra-sentential anaphora as a testing ground,I shall re-hypothesise that languages in the world can roughly be divided into two groups:syntactic and pragmatic.Finally,I shall outline an analysis of long-distance reflexivisation in Chinese in terms of my neo-Gricean pragmatic theory of anaphora.

Analysis of the Energy and Environmental Sustainability of a Built Space System: The Case of Patte d’Oie University Campus in Ouagadougou

The aim of this study was to carry out a dynamic simulation of the energy and environmental performance of a built space system, with a view to assessing its energy and environmental class. The use of a simulation and modeling tool, supported by various methodological references, formed the basis of our approach. Adopting a systemic perspective, we described the structural and functional aspects of the systems making up built spaces, as well as the associated energy flows. Our approach was also based on a typology, taking into account typical days, structural and functional configurations at different scales and angles of observation. The analysis tool we developed in Java was applied to the built space system of the Patte d’Oie university campus in Ouagadougou. Annual electricity consumption was measured at 124387.34 kWh, closely aligned with the average annual electricity bill (125224.31 kWh), with a maximum relative deviation of 1%, followed by a carbon emission balance of 58337.66 kg eq CO2 per year. This validation confirmed the effectiveness of our tool. In addition, following the analysis of electricity consumption using our tool, the university campus was classified in energy class B and environmental class C. These results will be based on the emission factors of the energy mix of the West African Economic and Monetary Union (WAEMU) territory, with particular emphasis on Burkina Faso.

A study on typology of areas densely populated with foreigners in Seoul, South Korea

This study identifies the types of areas in Seoul where foreigners are concentrated by reflecting the characteristics of their region of origin and residence in Seoul. Lack of cultural understanding and uniform policies for various immigrant communities are causing some social issues. Hence, this study aims to prepare the basic data from which the government can predict changes in ethnic areas and prepare policies suitable for each derived type. The 14 most populous immigrant communities in Seoul were investigated, and cluster analysis and ANOVA test were performed. This examination resulted in four immigrant community types. Each type has specific characteristics, which have influenced the creation and change of the built environment. Types 1 and 4 are collectivistic. These types gradually tend to change urban environments to emulate the environment in their region of origin. In addition, they make little effort to improve their degraded environments, and such areas become increasingly backward. In contrast, types 2 and 3 are individualistic and prefer to assimilate into a migrant region. The formation and change of the urban environment for each type can be predicted on the basis of these characteristics. From this information, the government can prepare an appropriate urban architecture policy for each type.

Typology of religious spaces in the urban historical area of Lhasa, Tibet

This work focuses on the spatial compositions and characteristics of religious sites and surrounding pilgrimage space in the city of Lhasa, which is the sacred center of Tibet. The modernization and urbanization of the city in recent decades have transformed the spatial and socioeconomic positions of its urban religious sites. The present study offers insights into the composition of urban religious spaces in the city of Lhasa with consideration to the spatiality and sociality of these spaces. After examining the current situations of retigious spaces, we classify the target spaces into five types using the duster analysis method and identify the characteristics of each type. We then discuss the socioeconomic values of each type of religious space and derive recommendations for planners. The analysis performed in this study may contribute in the soeciat planning for the protection of religious traditions.