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Aeroelastic modeling of wind loading on a cable-net supported glass wall 被引量:1
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作者 Zhifu Gu Letian Yang Yan Li Bin Chen 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2010年第3期409-415,共7页
Wind loading study on a cable-net supported glass wall is conducted by means of wind tunnel tests. An equiva- lent aeroelastic model is designed and constructed. Response of displacements of the wall is measured and a... Wind loading study on a cable-net supported glass wall is conducted by means of wind tunnel tests. An equiva- lent aeroelastic model is designed and constructed. Response of displacements of the wall is measured and analyzed. In order to design a glass wall under wind loading, the "wind- vibration factor" is estimated and discussed. In fact, the mech- anism of wind acting on the wall is commonly known not only as positive pressure, but also as negative pressure caused by the flow separation on the corners of the building. Due to the diffidence in the mechanism of wind acting, two typi- cal response cases are classified. The results show that the dynamic response of the structure caused by the negative pressure is stronger than that of the positive pressure case. To determine the aerodynamic wind loading on a flexible part of structure on a building, wind tunnel study may be useful and play an important role. 展开更多
关键词 Wind tunnel study Cable-net supported glasswall - Wind-vibration factor Aeroelastic model
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DEVELOPING EXPERT DECISION SUPPORT SYSTEM WTH VP-EXPERT AND LOTUS 1-2-3 IN RE-BLENDING BY USE
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作者 舒航 杨鹏 《Journal of China University of Mining and Technology》 1994年第2期104-111,共8页
An expert decision support system (EDSS) for multi-bins balance and contro1 of orequality in production ore bins of some large-scale open pit iron mine in China has been developed byexpert svitem tool software VP-EXPE... An expert decision support system (EDSS) for multi-bins balance and contro1 of orequality in production ore bins of some large-scale open pit iron mine in China has been developed byexpert svitem tool software VP-EXPERT and integration software LOTUS 1-2-3 in this paper. Itis known by practicing that a medium-scale EDSS constructed on microcomputer is completcly, feaasible by means of VP-EXEPERT to construct knowledge base system (KBS), LOTUS 1-2-3 tomake decision support system (DSS) and link them with BAT. 展开更多
关键词 VP-EXPERT LOTUS 1-2-3 ore-blending expert System decision support system expert decision support system
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EXACT SOLUTION FOR RECTANGULAR SLAB WITH THREE EDGES SIMPLY-SUPPORTED AND OTHER FREE
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作者 YU TENGHAIDepartment of Mathematics 《内江师范学院学报》 1996年第2期1-7,共7页
In this paper,we give all-sided pastic analysis of the rectangular slab with three edges simply-supported and other free.Here we discuss the following four cases:(1)The uniformly distributedload over the area a slab.(... In this paper,we give all-sided pastic analysis of the rectangular slab with three edges simply-supported and other free.Here we discuss the following four cases:(1)The uniformly distributedload over the area a slab.(2).A concentrated load act at midpoint of free edges slab.(3)A concen-trated load act at the center a slab.(4)The line load act along free edge of slab. 展开更多
关键词 The RECTANGULAR SLAB with three EDGES simply - supportED and OTHER free have wide the use value. But up to now only find the EXACT solution that a concentrated load act at midpoint of free edye a slab. The EXACT solution of OTHER support force
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A Novel Way to Prepareγ-A1_2O_3 Supported SO_4^(2-)/ZrO_2 Solid Superacid Catalysts for n-Butane Isomerization
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作者 Ting LEI Yi TANG +2 位作者 Wei Ming HUA Jin Suo XU Zi GAO (Department of Chemistry, Fudan University, Shanghai 200433) 《Chinese Chemical Letters》 SCIE CAS CSCD 2000年第1期89-92,共4页
Highly active solid superacid catalysts for n-butane isomerization, SZ/A1_2O_3-P, were prepared by supporting SO-(4-2)/ZrO2, (SZ) on y-A1_2O_3 carrier using a precipitation method. The activities of some catalysts wer... Highly active solid superacid catalysts for n-butane isomerization, SZ/A1_2O_3-P, were prepared by supporting SO-(4-2)/ZrO2, (SZ) on y-A1_2O_3 carrier using a precipitation method. The activities of some catalysts were enhanced significantly j The activity of the most active sample. 60%SZ/Al_2O3-P, was even about 2 times more active than that of the SZ catalyst. 展开更多
关键词 SO_4^(2-)/ZrO_2 n-Butane Isomerization γ-A1_2O_3 supported superacid catalysts.
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NEW SOLID BASE DERIVED FROM AIPO4-5 SUPPORTED KF
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作者 Jian Hua ZHU Qin Hug XU Hideshi HATTORI(Chemistry Department, Nanjing University.Nanjing 210093,China.)(Centre for Advanced Research of Energy Technology, Hokkaido University,Sapporo 060.Japan) 《Chinese Chemical Letters》 SCIE CAS CSCD 1996年第7期671-674,共4页
Dispersion of KF on AlPO4-5 molecular sieve created basic sites and caused 1654 cm- band of bidentate carbonate in CO2 adsorption.After pre-treated above 823K. 5%KF/AlPO4-5exhibited basic catalytic activity in the iso... Dispersion of KF on AlPO4-5 molecular sieve created basic sites and caused 1654 cm- band of bidentate carbonate in CO2 adsorption.After pre-treated above 823K. 5%KF/AlPO4-5exhibited basic catalytic activity in the isomerization of butenes at 273K. and the activity increasedwith the pre-treatment temperature up to 923K. 展开更多
关键词 NEW SOLID BASE DERIVED FROM AIPO4-5 supportED KF
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Yield Increasing and Quality Improving Effects of Smash-ridging Method("4453" Effects) and Its Potential in Benefiting the Nation and the People 被引量:4
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作者 韦本辉 《Agricultural Science & Technology》 CAS 2014年第10期1767-1769,共3页
Yuan Longping proposed that smash-ridging technology could be extend-ed widely nationwide. ln the research, smash-ridging technology reconstruct cultiva-tion layers with loose soils in agricultural fields, creating "... Yuan Longping proposed that smash-ridging technology could be extend-ed widely nationwide. ln the research, smash-ridging technology reconstruct cultiva-tion layers with loose soils in agricultural fields, creating "4453" effects, as fol ows: "Four increases" include to increase loosen soil quantity in cultivation layers, soil nutri-ents use, "water pool" in soils, and "oxygen pool" in soils. Four reductions are to reduce soil erosion, carbon emission, salt content and heavy metal in soils. Five resistances refer to improve crop resistance capacity in terms of drought, high tem-perature, lower temperature, disease and lodging. Three improvements indicate to enhance photosynthetic efficiency over 10%, yield in 10%-30% and quality over 5%. lt is researched that without additional chemical fertilizer, yield could increase by 10% by labor force, animal, tractor or smash-ridging machine. What’s more, by smash-ridging cultivation, the depth can be 20 times or higher compared with tractor cultivation, with looser soils. lt is estimated that if smash-ridging cultivation is applied once in agricultural lands in China, present soil layers can be twice as deep as present. Specifical y, the thickness of loose soil-layers could be extended from 10-18 cm at present to 25-35 cm, and natural rainfal would increase by 40 bil ion cm3. After vitalization of soil nutrients, chemical fertilizer would decrease by 7 bil ion kg, and the increased c rops would feed more than 300 mil ion population as per yield at 7 50 kg/hm2. 展开更多
关键词 Smash-ridging technology Extension nationwide lncrease range in 10%-30% supporting more 300 mil ion population"4453" effects Development potential
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Key technologies and equipment for a fully mechanized top-coal caving operation with a large mining height at ultra-thick coal seams 被引量:61
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作者 Jinhua Wang Bin Yu +4 位作者 Hongpu Kang Guofa Wang Debing Mao Yuntao Liang Pengfei Jiang 《International Journal of Coal Science & Technology》 EI 2015年第2期97-162,共66页
Thick and ultra-thick coal seams are main coal seams for high production rate and high efficiency in Chinese coal mines, which accounts for 44 % of the total minable coal reserve. A fully mechanized top-coal caving mi... Thick and ultra-thick coal seams are main coal seams for high production rate and high efficiency in Chinese coal mines, which accounts for 44 % of the total minable coal reserve. A fully mechanized top-coal caving mining method is a main underground coal extraction method for ultra-thick coal seams. The coal extraction technologies for coal seams less than 14 m thick were extensively used in China. However, for coal seams with thickness greater than 14 m, there have been no reported cases in the world for underground mechanical extraction with safe performance, high efficiency and high coal recovery ratio. To deal with this case, China Coal Technology & Engineering Group, Datong Coal Mine Group, and other 15 organizations in China launched a fundamental and big project to develop coal mining technologies and equipment for coal seams with thicknesses greater than 14 m. After the completion of the project, a coal extraction method was developed for top-coal caving with a large mining height, as well as a ground control theory for ultra-thick coal seams. In addition, the mining technology for top-coal caving with a large mining height, the ground support technology for roadway in coal seams with a large cross-section, and the prevention and control technology for gas and fire hazards were developed and applied. Furthermore, a hydraulic support with a mining height of 5.2 m, a shearer with high reliability, and auxiliary equipment were developed and manufactured. Practical implication on the technologies and equipment developed was successfully completed at the No. 8105 coal face in the Tashan coal mine, Datong, China. The major achievements of the project are summarized as follows: 1. A top-coal caving method for ultra-thick coal seams is proposed with a cutting height of 5 m and a top-coal caving height of 15 m. A structural mechanical model of overlying strata called cantilever beam-articulated rock beam is established. Based on the model, the load resistance of the hydraulic support with a large mining height for top-coal caving method is determined. With the analysis, the movement characteristics of the top coal and above strata are evaluated during top-coal caving operation at the coal face with a large mining height. Furthermore, there is successful development of comprehensive technologies for preventing and controlling spalling of the coal wall, and the top-coal caving technology with high efficiency and high recovery at the top-coal caving face with a large mining height. This means that the technologies developed have overcome the difficulties in strata control, top-coal caving with high efficiency and high coal recovery, and enabled to achieve a production rate of more than 10 Mtpa at a single top-coal caving face with a large mining height in ultra-thick coal seams; 2. A hydraulic support with 5.2 m supporting height and anti-rockburst capacity, a shearer with high reliability, a scraper conveyor with a large power at the back of face, and a large load and long distance headgate belt conveyor have been successfully developed for a top-coal caving face with large mining height. The study has developed the key technologies for improving the reliability of equipment at the coal face and has overcome the challenges in equipping the top-coal caving face with a large mining height in ultra-thick coal seams; 3. The deformation characteristics of a large cross-section roadway in ultra-thick coal seams are discovered. Based on the findings above, a series of bolt materials with a high yielding strength of 500-830 MPa and a high extension ratio, and cable bolt material with a 1 × 19 structure, large tonnage and high extension ratio are developed. In addition, in order to achieve a safe roadway and a fast face advance, installation equipment for high pre-tension bolt is developed to solve the problems with the support of roadway in coal seams for top-coal caving operation with a large mining height; 4. The characteristics of gas distribution and uneven emission at top-coal caving face with large mining height in ultra-thick coal seams are evaluated. With the application of the technologies of gas drainage in the roof, the difficulties in gas control for high intensive top-coal caving mining operations, known as "low gas content, high gas emission", are solved. In addition, large flow-rate underground mobile equipment for making nitrogen are developed to solve the problems with fire prevention and safe mining at a top-coal caving face with large mining height and production rate of more than 10 Mtpa. A case study to apply the developed technologies has been conducted at the No. 8105 face, the Tashan coal mine in Datong, China. The case study demonstrates that the three units of equipment, i.e., the support, shearer and scraper conveyor, are rationally equipped. Average equipment usage at the coal face is 92.1%. The coal recovery ratio at the coal face is up to 88.9 %. In 2011, the coal production at the No. 8105 face reached 10.849 Mtpa, exceeding the target of 10 Mtpa for a topcoal caving operation with large mining height performed by Chinese-made mining equipment. The technologies and equipment developed provide a way for extracting ultra-thick coal seams. Currently, the technologies and equipment are used in 13 mining areas in China including Datong, Pingshuo, Shendong and Xinjiang. With the exploitation of coal resources in Western China, there is great potential for the application of the technologies and equipment developed. 展开更多
关键词 Ultra-thick coal seams Top-coal caving mining Large mining height Mining method - Mining equipment Roadway support Safety guarantee
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Effect of temperature difference load of 32 m simply supported box beam bridge on track vertical irregularity 被引量:5
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作者 Kaize Xie Jun Xing +3 位作者 Li Wang Chunxiang Tian Rong Chen Ping Wang 《Journal of Modern Transportation》 2015年第4期262-271,共10页
In order to study the effect of temperature difference load (TDL) along the vertical direction of a simply supported beam bridge section on the vertical irregularity, a rail-bridge-piers calculation model was establ... In order to study the effect of temperature difference load (TDL) along the vertical direction of a simply supported beam bridge section on the vertical irregularity, a rail-bridge-piers calculation model was established. Taking 32 m simply supported box beam bridge which is widely used in the construction of pas- senger dedicated line in China as an example, influences of the temperature variation between the bottom and top of the bridge, temperature curve index, type of temperature gradient, and beam height on track vertical irregularity were analyzed with the model. The results show that TDL has more effects on long wave track irregularity than on short one, and the wavelength mainly affected is approxi- mately equal to the beam span. The amplitude of irregu- larity caused by TDL is largely affected by the temperature variation, temperature curve index, and type of temperature gradient, so it is necessary to monitor the temperaturedistribution of bridges in different regions to provide accurate calculation parameters. In order to avoid the irregularity exceeding the limit values, the height of 32, 48, and 64 m simply supported box beam bridges must not be less than 2.15, 3.2, and 4.05 m, respectively. 展开更多
关键词 Simply supported beam bridge Temperaturegradient Vertical irregularity - Beam height
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Real-time crash prediction on freeways using data mining and emerging techniques 被引量:4
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作者 Jinming You Junhua Wang Jingqiu Guo 《Journal of Modern Transportation》 2017年第2期116-123,共8页
Recent advances in intelligent transportation system allow traffic safety studies to extend from historic data-based analyses to real-time applications. The study presents a new method to predict crash likelihood with... Recent advances in intelligent transportation system allow traffic safety studies to extend from historic data-based analyses to real-time applications. The study presents a new method to predict crash likelihood with traffic data collected by discrete loop detectors as well as the web-crawl weather data. Matched case-control method and support vector machines (SVMs) technique were employed to identify the risk status. The adaptive synthetic over-sampling technique was applied to solve the imbalanced dataset issues. Random forest technique was applied to select the contributing factors and avoid the over-fitting issues. The results indicate that the SVMs classifier could successfully classify 76.32% of the crashes on the test dataset and 87.52% of the crashes on the overall dataset, which were relatively satisfactory compared with the results of the previous studies. Compared with the SVMs classifier without the data, the SVMs classifier with the web-crawl weather data increased the crash prediction accuracy by 1.32% and decreased the false alarm rate by 1.72%, showing the potential value of the massive web weather data. Mean impact value method was employed to evaluate the variable effects, and the results are identical with the results of most of previous studies. The emerging technique based on the discrete traffic data and web weather data proves to be more applicable on real- time safety management on freeways. 展开更多
关键词 Crash prediction detectors Web-crawl data Real time - Discrete loop support vector machines
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Stable CuO/La_(2)Sn_(2)O_(7) catalysts for soot combustion:Study on the monolayer dispersion behavior of CuO over a La_(2)Sn_(2)O_(7) pyrochlore support 被引量:2
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作者 Xiaohui Feng Rui Liu +6 位作者 Xianglan Xu Yunyan Tong Shijing Zhang Jiacheng He Junwei Xu Xiuzhong Fang Xiang Wang 《Chinese Journal of Catalysis》 SCIE EI CAS CSCD 2021年第3期396-408,共13页
To understand the dispersion behavior of metal oxides on composite oxide supports and with the expectation of developing more feasible catalysts for soot oxidation,CuO/La_(2)Sn_(2)O_(7)samples containing varied CuO lo... To understand the dispersion behavior of metal oxides on composite oxide supports and with the expectation of developing more feasible catalysts for soot oxidation,CuO/La_(2)Sn_(2)O_(7)samples containing varied CuO loadings were fabricated and characterized by different techniques and density functional theory calculations.In these catalysts,a spontaneous dispersion of CuO on the La_(2)Sn_(2)O_(7)pyrochlore support formed,having a monolayer dispersion capacity of 1.90 mmol CuO/100 m^(2) La_(2)Sn_(2)O_(7)surface.When loaded below this capacity,CuO exists in a sub-monolayer or monolayer state.X-ray photoelectron spectroscopy(XPS),Raman spectroscopy,and Bader charge and density of states analyses indicate that there are strong interactions between the sub-monolayer/monolayer CuO and the La_(2)Sn_(2)O_(7)support,mainly through the donation of electrons from Cu to Sn at the B-sites of the structure.In contrast,Cu has negligible interactions with La at the A-sites.This suggests that,in composite oxide supports containing multiple metals,the supported metal oxide interacts preferentially with one kind of metal cation in the support.The Raman,in situ diffuse reflectance infrared Fourier transform spectroscopy,and XPS results confirmed the formation of both O2^(-)and O2^(2-)as the active sites on the surfaces of the CuO/La_(2)Sn_(2)O_(7)catalysts,and the concentration of these active species determines the soot combustion activity.The number of active oxygen anions increased with increase in CuO loading until the monolayer dispersion capacity was reached.Above the monolayer dispersion capacity,microsized CuO crystallites formed,and these had a negative effect on the generation of active surface oxygen sites.In summary,a highly active catalyst can be prepared by covering the surface of the La_(2)Sn_(2)O_(7)support with a CuO monolayer. 展开更多
关键词 CuO/La_(2)Sn_(2)O_(7)catalyst Soot combustion DFT calculations Preferential interaction Monolayer dispersion on pyrochlore support Active O2^(-)and O2^(2-)sites
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Formation of Hybrid Ring Structure of Cyanurate/Isocyanurate in the Reaction be-tween 2,4,6-Tris(4-Phenyl-Phenoxy)-1, 3,5-Triazine and Phenyl Glycidyl Ether
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作者 Daisuke Ohno Kazuya Zenyoji +2 位作者 Youji Kurihara Kazuyoshi Ueda Hitoshi Habuka 《International Journal of Organic Chemistry》 CAS 2016年第2期117-125,共9页
Reaction products of 2,4,6-tris(4-phenyl-phenoxy)-1,3,5-triazine derived from 4-phenylphenol cyanate ester and phenyl glycidyl ether were analyzed. In addition to an isocyanurate compound and an oxazolidone compound w... Reaction products of 2,4,6-tris(4-phenyl-phenoxy)-1,3,5-triazine derived from 4-phenylphenol cyanate ester and phenyl glycidyl ether were analyzed. In addition to an isocyanurate compound and an oxazolidone compound which were well known as reaction products of cyanate esters and epoxy resins, compounds with hybrid ring structure of cyanurate/isocyanurate were determined. Gibbs free energies of the compound having hybrid ring structure of cyanurate/isocyanurate with two isocyanurate moiety were found to be lower than that of the compound with cyanurate ring structure through calculations. Calculation data supported the existence of hybrid ring structure of cy-anurate/isocyanurate. It was revealed that isomerization from cyanurate to isocyanurate occurs via hybrid ring structure of cyanurate/isocyanurate in the reaction of aryl cyanurate and epoxy. 展开更多
关键词 Reaction products of 2 4 6-tris(4-phenyl-phenoxy)-1 3 5-triazine derived from 4-phenylphenol cya-nate ester and phenyl glycidyl ether were analyzed. In addition to an isocyanurate compound and an oxazolidone compound which were well known as reaction products of cyanate esters and epoxy resins compounds with hybrid ring structure of cyanurate/isocyanurate were determined. Gibbs free energies of the compound having hybrid ring structure of cyanurate/isocyanurate with two isocyanurate moiety were found to be lower than that of the compound with cyanurate ring struc-ture through calculations. Calculation data supported the existence of hybrid ring structure of cy-anurate/isocyanurate. It was revealed that isomerization from cyanurate to isocyanurate occurs via hybrid ring structure of cyanurate/isocyanurate in the reaction of aryl cyanurate and epoxy.
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顺河高架桥大跨度盖梁无落地支架施工技术 被引量:2
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作者 党相勇 《工程建设与设计》 2007年第10期84-87,共4页
盖梁无落地支架施工是利用已施工完毕的混凝土立柱作为竖向承重结构,在立柱适当高度处预埋铁件作牛腿,之上架设横梁作为盖梁模板的搭设平台,从而避免搭设落地支架的一种施工技术。结合济南顺河高架桥西洛河段大跨度盖梁无落地支架施工实... 盖梁无落地支架施工是利用已施工完毕的混凝土立柱作为竖向承重结构,在立柱适当高度处预埋铁件作牛腿,之上架设横梁作为盖梁模板的搭设平台,从而避免搭设落地支架的一种施工技术。结合济南顺河高架桥西洛河段大跨度盖梁无落地支架施工实例,阐述了该施工技术的结构设计与关键施工工艺。 展开更多
关键词 盖梁 无落地支架 结构设计 施工技术
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Comprehensive Overview on Computational Intelligence Techniques for Machinery Condition Monitoring and Fault Diagnosis 被引量:18
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作者 Wan Zhang Min-Ping Jia +1 位作者 Lin Zhu Xiao-An Yan 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2017年第4期782-795,共14页
Computational intelligence is one of the most powerful data processing tools to solve complex nonlinear problems, and thus plays a significant role in intelligent fault diagnosis and prediction. However, only few com-... Computational intelligence is one of the most powerful data processing tools to solve complex nonlinear problems, and thus plays a significant role in intelligent fault diagnosis and prediction. However, only few com- prehensive reviews have summarized the ongoing efforts of computational intelligence in machinery condition moni- toring and fault diagnosis. The recent research and devel- opment of computational intelligence techniques in fault diagnosis, prediction and optimal sensor placement are reviewed. The advantages and limitations of computational intelligence techniques in practical applications are dis- cussed. The characteristics of different algorithms are compared, and application situations of these methods are summarized. Computational intelligence methods need to be further studied in deep understanding algorithm mech- anism, improving algorithm efficiency and enhancing engineering application. This review may be considered as a useful guidance for researchers in selecting a suit- able method for a specific situation and pointing out potential research directions. 展开更多
关键词 Computational intelligence Machinerycondition monitoring Fault diagnosis Neural networkFuzzy logic support vector machine - Evolutionaryalgorithms
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System identification modelling of ship manoeuvring motion based on ?- support vector regression 被引量:9
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作者 王雪刚 邹早建 +1 位作者 侯先瑞 徐锋 《Journal of Hydrodynamics》 SCIE EI CSCD 2015年第4期502-512,共11页
Based on the ε - support vector regression, three modelling methods for the ship manoeuvring motion, i.e., the white-box modelling, the grey-box modelling and the black-box modelling, are investigated. The 10°/1... Based on the ε - support vector regression, three modelling methods for the ship manoeuvring motion, i.e., the white-box modelling, the grey-box modelling and the black-box modelling, are investigated. The 10°/10°, 20°/20° zigzag tests and the 35° turning circle manoeuvre are simulated. Part of the simulation data for the 20°/20° zigzag test are used to train the support vectors, and the trained support vector machine is used to predict the whole 20° / 20° zigzag test. Comparison between the simula- ted and predicted 20° / 20° zigzag test shows a good predictive ability of the three modelling methods. Then all mathematical models obtained by the modelling methods are used to predict the 10°/10° zigzag test and 35° turning circle manoeuvre, and the predicted results are compared with those of simulation tests to demonstrate the good generalization performance of the mathematical models. Finally, the modelling methods are analyzed and compared with each other in terms of the application conditions, the prediction accuracy and the computation speed. An appropriate modelling method can be chosen according to the intended use of the mathematical models and the available data for the system identification. 展开更多
关键词 ship manoeuvring hydrodynamic coefficients mathematical model system identification ε - support vector regression
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无支架盖梁施工新技术的推广应用 被引量:4
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作者 王伟捷 《城市道桥与防洪》 2010年第7期80-85,共6页
该文结合上海S32高速公路闵浦大桥西侧引桥段的盖梁施工实践,对高架桥无落地支架施工新技术进行了应用和推广。详细介绍了施工工艺,包括安装、吊装、拆模等各个阶段的要点和难点。
关键词 盖梁 无落地支架 组合钢模 闵浦大桥 上海
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Sialic acid accelerates the electrophoretic velocity of injured dorsal root ganglion neurons 被引量:3
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作者 Chen-xu Li Guo-ying Ma +1 位作者 Min-fang Guo Ying Liu 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第6期972-975,共4页
Peripheral nerve injury has been shown to result in ectopic spontaneous discharges on soma and injured sites of sensory neurons, thereby inducing neuropathic pain. With the increase of membrane proteins on soma and in... Peripheral nerve injury has been shown to result in ectopic spontaneous discharges on soma and injured sites of sensory neurons, thereby inducing neuropathic pain. With the increase of membrane proteins on soma and injured site neurons, the negatively charged sialic acids bind to the external domains of membrane proteins, resulting in an increase of this charge. We therefore speculate that the electrophoretic velocity of injured neurons may be faster than non-injured neurons. The present study established rat models of neuropathic pain via chronic constriction injury. Results of the cell electrophoresis test revealed that the electrophoretic velocity of injured neuronal cells was faster than that of non-injured (control) cells. We then treated cells with divalent cations of Ca2+ and organic compounds with positive charges, polylysine to counteract the negatively charged sialic acids, or neuraminidase to specifically remove sialic acids from the membrane surface of injured neurons. All three treatments significantly reduced the electrophoretic velocity of injured neuronal cells. These findings suggest that enhanced sialic acids on injured neurons may accelerate the electrophoretic velocity of injured neurons. 展开更多
关键词 This study was supported by the Natural Science Foundation of Shanxi Province in China No. 2012011042-3.
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Radiotherapy in combination with systemic therapies for brain metastases:current status and progress 被引量:7
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作者 Lei Liu Wanqi Chen +6 位作者 Ruopeng Zhang Yuekun Wang Penghao Liu Xin Lian Fuquan Zhang Yu Wang Wenbin Ma 《Cancer Biology & Medicine》 SCIE CAS CSCD 2020年第4期910-922,共13页
Brain metastases(BMs)are the most common cause of intracranial neoplasms in adults with poor prognosis.Most BMs originate from lung cancer,breast cancer,or melanoma.Radiotherapy(RT),including whole brain radiotherapy(... Brain metastases(BMs)are the most common cause of intracranial neoplasms in adults with poor prognosis.Most BMs originate from lung cancer,breast cancer,or melanoma.Radiotherapy(RT),including whole brain radiotherapy(WBRT)and stereotactic radiation surgery(SRS),has been widely explored and is considered a mainstay anticancer treatment for BMs.Over the past decade,the advent of novel systemic therapies has revolutionized the treatment of BMs.In this context,there is a strong rationale for using a combination of treatments based on RT,with the aim of achieving both local disease control and extracranial disease control.This review focuses on describing the latest progress in RT as well as the synergistic effects of the optimal combinations of RT and systemic treatment modalities for BMs,to provide perspectives on current treatments. 展开更多
关键词 supported by grants from Beijing Municipal Natural Science Foundation(Grant No.7202150) Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(Grant No.2016-I2M-2-001)
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Ion Channel Behavior of a Supported Bilayer Lipid Membrane Composed of 5,5-Ditetradecyl-2-(2-trimethyl-ammonioethyl)-1,3-dioxane Bromide Modified Glassy Carbon Electrode
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作者 龚静鸣 林祥钦 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2003年第7期756-760,共5页
A synthetic cationic surfactant, 5,5-ditetradecyl-2-(2-trimethyl-ammonioethyl)-1,3-dioxane bromide (DTDB), was used to construct a supported bilayer lipid membrane (s-BLM) coated on an underlying glassy carbon electro... A synthetic cationic surfactant, 5,5-ditetradecyl-2-(2-trimethyl-ammonioethyl)-1,3-dioxane bromide (DTDB), was used to construct a supported bilayer lipid membrane (s-BLM) coated on an underlying glassy carbon electrode (GCE). Electrochemical impedance spectroscopy (EIS), small-angle X-ray diffraction (SAXD) and cyclic voltammetry were used to characterize the s-BLM. Both EIS and SAXD data indicated that the synthetic lipid exists as a well-oriented bilayer in the membrane. The voltammetric study showed that the lipid membrane can open ion channels in the presence of C1O4- stimulant with Ru(bpy)32+ as marker ions and give distinct channel currents. The channels can be closed and open up again many times by removing or introducing ClO4- anions. 展开更多
关键词 5 5-ditetradecyl-2- ( 2-trimethyl-ammonioethyl) -1 3-dioxane bromide ion channel behavior electrochemical impedance spectroscopy small-angle X-ray diffraction supported bilayer lipid membrane
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融合多特征的异源视频复制-粘贴篡改检测 被引量:1
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作者 李富贵 黄添强 +1 位作者 苏立超 苏伟峰 《山东大学学报(工学版)》 CAS 北大核心 2013年第4期32-38,共7页
相比传统的视频帧插入或帧删除以及视频双压缩等篡改方式,复制-粘贴篡改更能直接的改变视频内容。因此,本研究提出一种融合多特征的异源视频复制-粘贴篡改检测方法。对于经过帧内复制-粘贴篡改的视频,其视频帧内会引入一些尖锐的变化,... 相比传统的视频帧插入或帧删除以及视频双压缩等篡改方式,复制-粘贴篡改更能直接的改变视频内容。因此,本研究提出一种融合多特征的异源视频复制-粘贴篡改检测方法。对于经过帧内复制-粘贴篡改的视频,其视频帧内会引入一些尖锐的变化,比如线条、边缘和角点等,而二维相位一致性可以很好的检测出这些变化。同时,来自异源视频帧复制的区域块会使得帧内引入不同的模式噪声,可以利用模式噪声和二维相位一致性提取视频帧的特征,然后将特征融合进行SVM分类实验来检测篡改视频。实验表明该算法可以有效地检测异源复制-粘贴篡改的视频。 展开更多
关键词 复制-粘贴篡改 复制-粘贴检测 模式噪声 二维相位一致性 SVM(support VECTOR machine)
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