The hippocampal region of the brain is important for encoding environment inputs and memory formation. However, the underlying mechanisms are unclear. To investigate the behavior of indi-vidual neurons in response to ...The hippocampal region of the brain is important for encoding environment inputs and memory formation. However, the underlying mechanisms are unclear. To investigate the behavior of indi-vidual neurons in response to somatosensory inputs in the hippocampal CA1 region, we recorded and analyzed changes in local ifeld potentials and the ifring rates of individual pyramidal cells and interneurons during tail clamping in urethane-anesthetized rats. We also explored the mechanisms underlying the neuronal responses. Somatosensory stimulation, in the form of tail clamping, chan-ged local ifeld potentials into theta rhythm-dominated waveforms, decreased the spike ifring of py-ramidal cells, and increased interneuron ifring. In addition, somatosensory stimulation attenuated orthodromic-evoked population spikes. These results suggest that somatosensory stimulation sup-presses the excitability of pyramidal cells in the hippocampal CA1 region. Increased inhibition by local interneurons might underlie this effect. These ifndings provide insight into the mechanisms of signal processing in the hippocampus and suggest that sensory stimulation might have thera-peutic potential for brain disorders associated with neuronal hyperexcitability.展开更多
The spike-grain structure and yield data of winter wheat observed at 10 winter wheat observation stations in Jiangsu agrometeorological observation stations in the China Meteorological Observation Network were used to...The spike-grain structure and yield data of winter wheat observed at 10 winter wheat observation stations in Jiangsu agrometeorological observation stations in the China Meteorological Observation Network were used to design the assessment model and evaluation criteria of the effects of climate change on spikegrain structure and yield of winter wheat. The linear regression method was used to determine the parameters of the assessment model,and the climate fact extrapolation method was used to determine future climate change scenarios. The effects of climate change on spike-grain structure and yield of winter wheat in Jiangsu Province were calculated and analyzed finally. The results showed that with the climate change,the meteorological conditions during the growth and development of winter wheat changed,which caused the number of effective spikes to decrease,and the number of grains per spike and thousand-grain weight to increase,and this new type of spike-grain structure combination was beneficial to the increase of the unit yield of winter wheat. The variations of meteorological elements caused by climate change during winter wheat growth and development had different effects on spike-grain structure at different growth stages. The spike-grain structure had an "increasing-decreasing" periodic variation with the growth period overall,with a period of one to three stages. The relationship between winter wheat growth and development and meteorological conditions can be adjusted in real time through stress-resistant cultivation techniques to achieve the high-yield and high-quality cultivation target of winter wheat production.展开更多
基金supported by Major State Basic Research Development Program of China(973 Program),No.2011CB504400
文摘The hippocampal region of the brain is important for encoding environment inputs and memory formation. However, the underlying mechanisms are unclear. To investigate the behavior of indi-vidual neurons in response to somatosensory inputs in the hippocampal CA1 region, we recorded and analyzed changes in local ifeld potentials and the ifring rates of individual pyramidal cells and interneurons during tail clamping in urethane-anesthetized rats. We also explored the mechanisms underlying the neuronal responses. Somatosensory stimulation, in the form of tail clamping, chan-ged local ifeld potentials into theta rhythm-dominated waveforms, decreased the spike ifring of py-ramidal cells, and increased interneuron ifring. In addition, somatosensory stimulation attenuated orthodromic-evoked population spikes. These results suggest that somatosensory stimulation sup-presses the excitability of pyramidal cells in the hippocampal CA1 region. Increased inhibition by local interneurons might underlie this effect. These ifndings provide insight into the mechanisms of signal processing in the hippocampus and suggest that sensory stimulation might have thera-peutic potential for brain disorders associated with neuronal hyperexcitability.
基金Supported by 2016 Key Business Project of Jiangsu Meteorological Bureau(20161122)
文摘The spike-grain structure and yield data of winter wheat observed at 10 winter wheat observation stations in Jiangsu agrometeorological observation stations in the China Meteorological Observation Network were used to design the assessment model and evaluation criteria of the effects of climate change on spikegrain structure and yield of winter wheat. The linear regression method was used to determine the parameters of the assessment model,and the climate fact extrapolation method was used to determine future climate change scenarios. The effects of climate change on spike-grain structure and yield of winter wheat in Jiangsu Province were calculated and analyzed finally. The results showed that with the climate change,the meteorological conditions during the growth and development of winter wheat changed,which caused the number of effective spikes to decrease,and the number of grains per spike and thousand-grain weight to increase,and this new type of spike-grain structure combination was beneficial to the increase of the unit yield of winter wheat. The variations of meteorological elements caused by climate change during winter wheat growth and development had different effects on spike-grain structure at different growth stages. The spike-grain structure had an "increasing-decreasing" periodic variation with the growth period overall,with a period of one to three stages. The relationship between winter wheat growth and development and meteorological conditions can be adjusted in real time through stress-resistant cultivation techniques to achieve the high-yield and high-quality cultivation target of winter wheat production.
