Objective:This study aimed to examine the causal model of eating behaviors among pregnant women working in industrial factories.Methods:This cross-sectional study was conducted on 210 participants,attending 4 healthca...Objective:This study aimed to examine the causal model of eating behaviors among pregnant women working in industrial factories.Methods:This cross-sectional study was conducted on 210 participants,attending 4 healthcare centers,at a tertiary care hospital in Chonburi province,Thailand.Data were collected using 7 questionnaires:demographic form,eating behavior questionnaire,perceived benefits of the healthy eating questionnaire,perceived barriers to the healthy eating questionnaire,perceived self-efficacy questionnaire,social support questionnaire,and accessibility to healthy foods questionnaire.Descriptive statistics and path analysis were used for data analysis.Results:The participants had relatively high mean scores for eating behaviors.The final model fitted well with the dataχ^(2)=12.86,df=10,P=0.23;χ^(2)/df=1.29;comparative fit index(CFI)=0.98;goodness-of-fit index(GFI)=0.98;adjusted goodness-of-fit index(AGFI)=0.95;root mean square error of approximation(RMSEA)=0.04.Four factors-perceived benefits(β=0.13,P<0.05),perceived self-efficacy in healthy eating(β=0.22,P<0.001),pregnancy planning(β=0.28,P<0.001),and accessibility to healthy foods in the factory(β=0.12,P<0.05)-positively affected eating behavior,while only perceived barriers to healthy eating had a negative effect on eating behavior(β=−0.24,P<0.001).All the above factors explained 27.2%of the variance in eating behaviors.Conclusions:Nurses or healthcare providers can apply these findings to create an eating behavior modification program,focusing on pregnancy planning,behavior-specific variables,and interpersonal and situational influence,to promote the nutritional status of pregnant women working in industrial factories.展开更多
The rapid advancement of fundamental theories and computing capacity has brought artificial intelligence,internet of things, extended reality, and many other new intelligent technologies into our daily lives. Due to t...The rapid advancement of fundamental theories and computing capacity has brought artificial intelligence,internet of things, extended reality, and many other new intelligent technologies into our daily lives. Due to the lack of interpretability and reliability guarantees, it is extremely challenging to apply these technologies directly to real-world industrial systems. Here we present a new paradigm for establishing parallel factories in metaverses to accelerate the deployment of intelligent technologies in real-world industrial systems: QAII-1.0. Based on cyber-physical-social systems,QAII-1.0 incorporates complex social and human factors into the design and analysis of industrial operations and is capable of handling industrial operations involving complex social and human behaviors. In QAII-1.0, a field foundational model called Eu Artisan combined with scenarios engineering is developed to improve the intelligence of industrial systems while ensuring industrial interpretability and reliability. Finally, parallel oil fields in metaverses are established to demonstrate the operating procedure of QAII-1.0.展开更多
Development and utilization of“liquid sunshine”could be one of key solutions to deal with the issues of fossil fuel depletion and increasing carbon dioxide.Cyanobacteria are the only prokaryotes capable of performin...Development and utilization of“liquid sunshine”could be one of key solutions to deal with the issues of fossil fuel depletion and increasing carbon dioxide.Cyanobacteria are the only prokaryotes capable of performing oxygenic photosynthesis,and their activity accounts for~25%of the total carbon fixation on earth.More importantly,besides their traditional roles as primary producers,cyanobacteria could be modified as“photosynthetic cell factories”to produce renewable fuels and chemicals directly from CO_(2) driven by solar energy,with the aid of cutting-edging synthetic biology technology.Towards their large-scale biotechnological application in the future,many challenges still need to be properly addressed,among which is cyanobacterial cell factories inevitably suffer from high light(HL)stress during large-scale outdoor cultivation,resulting in photodamage and even cell death,limiting their productivity.In this review,we critically summarized recent progress on deciphering molecular mechanisms to HL and developing HL-tolerant chassis in cyanobacteria,aiming at facilitating construction of HLresistant chassis and promote the future application of the large-scale outdoor cultivation of cyanobacterial cell factories.Finally,the future directions on cyanobacterial chassis engineering were discussed.展开更多
Plus-strand RNA virus replication occurs in tight association with cytoplasmic host cell membranes. Both, viral and cellular factors cooperatively generate distinct organelle-like structures, designated viral replicat...Plus-strand RNA virus replication occurs in tight association with cytoplasmic host cell membranes. Both, viral and cellular factors cooperatively generate distinct organelle-like structures, designated viral replication factories. This compartmentalization allows coordination of the different steps of the viral replication cycle, highly efficient genome replication and protection of the viral RNA from cellular defense mechanisms. Electron tomography studies conducted during the last couple of years revealed the three dimensional structure of numerous plus-strand RNA virus replication compartments and highlight morphological analogies between different virus families. Based on the morphology of virusinduced membrane rearrangements, we propose two separate subclasses: the invaginated vesicle/spherule type and the double membrane vesicle type. This review discusses common themes and distinct differences in the architecture of plus-strand RNA virus-induced membrane alterations and summarizes recent progress that has been made in understanding the complex interplay between viral and co-opted cellular factors in biogenesis and maintenance of plus-strand RNA virus replication factories.展开更多
In this paper we show that the MDA can be considered as a software industrialization pattern (or a software factory). Nearly all industries today are haunted with how to reduce costs, improve quality, faster time-to-m...In this paper we show that the MDA can be considered as a software industrialization pattern (or a software factory). Nearly all industries today are haunted with how to reduce costs, improve quality, faster time-to-market and to maximize profits. These challenges are particularly relevant to the software industry, because it still lags behind other technology sectors as regards industrialization and the timely delivery of software products. Most software are still of poor quality, always finished after deadlines (most don’t finish at all), and are very labour intensive. Here, we discuss the MDA as an approach that may help solving at the same time both problems of industrialization and ever-changing software infrastructures. We propose a MDA Engine based on a real case study in an IT services company. It is a proposal for a framework to create custom MDA tools, based on XMI, XSLT and the Visitor Pattern.展开更多
The increasing demand for software engineers cannot completely be fulfilled by university education and conventional training approaches due to limited capacities.Accordingly,an alternative approach is necessary where...The increasing demand for software engineers cannot completely be fulfilled by university education and conventional training approaches due to limited capacities.Accordingly,an alternative approach is necessary where potential software engineers are being educated in software engineering skills using new methods.We suggest micro tasks combined with theoretical lessons to overcome existing skill deficits and acquire fast trainable capabilities.This paper addresses the gap between demand and supply of software engineers by introducing an actionoriented and scenario-based didactical approach,which enables non-computer scientists to code.Therein,the learning content is provided in small tasks and embedded in learning factory scenarios.Therefore,different requirements for software engineers from the market side and from an academic viewpoint are analyzed and synthesized into an integrated,yet condensed skills catalogue.This enables the development of training and education units that focus on the most important skills demanded on the market.To achieve this objective,individual learning scenarios are developed.Of course,proper basic skills in coding cannot be learned over night but software programming is also no sorcery.展开更多
Purpose: Leagile manufacturing is one of the time-based manufacturing practices used to improve factory performance. It is a practice that combines initiatives of Lean and agile manufacturing under certain enabling co...Purpose: Leagile manufacturing is one of the time-based manufacturing practices used to improve factory performance. It is a practice that combines initiatives of Lean and agile manufacturing under certain enabling competences. Therefore, the purpose of this study is investigate the combinative nature of time-based manufacturing practices under unique enabling competences and their impact on performance of factories in Uganda. Methodology: Firstly, the underlying factor structure of competences and time-based manufacturing was examined was conducted using Principal Component Analysis (PCA). Enabling competences and time-base manufacturing practices were modelled and validated for each using confirmatory factor analysis, particularly composite reliability, average variance extracted and convergent validity. A fully fledged structural equation model was used to test the impact of leagile manufacturing on performance of factories. Findings: The study results revealed that time-based manufacturing of lean, and leagile are related but differ, in terms of their enabling competences and philosophical orientation. The findings also revealed that when small and medium factories in Uganda adopt leagile practice, they are likely not improve their performance. This is perhaps due to the fact that small and medium factories have inadequate resources. Practical Implications: The study findings shed more insights on the factors that enable adoption and implementation of time-based manufacturing practices. The extent to which these competences are orchestrated determines the benefits derived from the time-based manufacturing practices. In addition, small and medium enterprises should keenly make a choice on the appropriate practices that purposely reduce their lead time and cost of conversion. Originality: This study investigated the combinative nature of time-based manufacturing practices under unique enabling competences and their impact on performance of factories in Uganda. It is among the few studies that provide evidence on the leagile model anchored in the appropriate enabling competences in the context of developing countries. The empirical survey was done on small and medium factories to validate a leagile manufacturing model and tested its impact on factory performance.展开更多
Experimentation has come a long in helping researchers achieve breakthroughs in their different scientific areas and engineering happens to be one of those areas with the most impact from experimental advancement. The...Experimentation has come a long in helping researchers achieve breakthroughs in their different scientific areas and engineering happens to be one of those areas with the most impact from experimental advancement. The need for valid experimental results free from biases and confounding conclusions has prompted the development of new experimental techniques that takes consideration of all applicable factor and combinations in providing answers on a research topic, and the Factorial Experimental design credited to Sir Ronald Fisher is one technique yielding highly valid results. This paper uses the factorial design of experiments to research the flexural impact of polyvinyl acetate fiber and layered concrete in construction. The experiment considered two levels of fiber contents and two levels of layers, and prepared samples with all combinations of the variable factors. The samples were tested after 7 days from casting for flexural strength and an advance statistical analysis was performed on the flexural responses of the samples using R-program. The results from the analyses revealed the significance of the variables to the flexural strength of the samples, as well as their interactions. The experiment concluded that based on the number of layers and fiber content used for the experiment, casting concrete in layers does have a significant negative effect on the flexural strength of concrete, and the failure pattern of concrete members under flexural load in evidently influenced by the material composition of the concrete, and that it can be evidently influenced by casting the concrete in layers.展开更多
文摘Objective:This study aimed to examine the causal model of eating behaviors among pregnant women working in industrial factories.Methods:This cross-sectional study was conducted on 210 participants,attending 4 healthcare centers,at a tertiary care hospital in Chonburi province,Thailand.Data were collected using 7 questionnaires:demographic form,eating behavior questionnaire,perceived benefits of the healthy eating questionnaire,perceived barriers to the healthy eating questionnaire,perceived self-efficacy questionnaire,social support questionnaire,and accessibility to healthy foods questionnaire.Descriptive statistics and path analysis were used for data analysis.Results:The participants had relatively high mean scores for eating behaviors.The final model fitted well with the dataχ^(2)=12.86,df=10,P=0.23;χ^(2)/df=1.29;comparative fit index(CFI)=0.98;goodness-of-fit index(GFI)=0.98;adjusted goodness-of-fit index(AGFI)=0.95;root mean square error of approximation(RMSEA)=0.04.Four factors-perceived benefits(β=0.13,P<0.05),perceived self-efficacy in healthy eating(β=0.22,P<0.001),pregnancy planning(β=0.28,P<0.001),and accessibility to healthy foods in the factory(β=0.12,P<0.05)-positively affected eating behavior,while only perceived barriers to healthy eating had a negative effect on eating behavior(β=−0.24,P<0.001).All the above factors explained 27.2%of the variance in eating behaviors.Conclusions:Nurses or healthcare providers can apply these findings to create an eating behavior modification program,focusing on pregnancy planning,behavior-specific variables,and interpersonal and situational influence,to promote the nutritional status of pregnant women working in industrial factories.
基金supported in part by the National Natural Science Foundation of China(1811463,62073321)Modeling,Decision and Control Algorithms for Servo Drive Systems。
文摘The rapid advancement of fundamental theories and computing capacity has brought artificial intelligence,internet of things, extended reality, and many other new intelligent technologies into our daily lives. Due to the lack of interpretability and reliability guarantees, it is extremely challenging to apply these technologies directly to real-world industrial systems. Here we present a new paradigm for establishing parallel factories in metaverses to accelerate the deployment of intelligent technologies in real-world industrial systems: QAII-1.0. Based on cyber-physical-social systems,QAII-1.0 incorporates complex social and human factors into the design and analysis of industrial operations and is capable of handling industrial operations involving complex social and human behaviors. In QAII-1.0, a field foundational model called Eu Artisan combined with scenarios engineering is developed to improve the intelligence of industrial systems while ensuring industrial interpretability and reliability. Finally, parallel oil fields in metaverses are established to demonstrate the operating procedure of QAII-1.0.
基金This research was supported by grants from the National Key Research and Development Program of China(No.2019YFA0904600,2018YFA0903600,2020YFA0906800 and 2018YFA0903000)the National Natural Science Foundation of China(No.31770035,31972931,91751102,31770100,31901017,31901016,32070083 and 21621004)Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(No.TSBICIP-KJGG-007).
文摘Development and utilization of“liquid sunshine”could be one of key solutions to deal with the issues of fossil fuel depletion and increasing carbon dioxide.Cyanobacteria are the only prokaryotes capable of performing oxygenic photosynthesis,and their activity accounts for~25%of the total carbon fixation on earth.More importantly,besides their traditional roles as primary producers,cyanobacteria could be modified as“photosynthetic cell factories”to produce renewable fuels and chemicals directly from CO_(2) driven by solar energy,with the aid of cutting-edging synthetic biology technology.Towards their large-scale biotechnological application in the future,many challenges still need to be properly addressed,among which is cyanobacterial cell factories inevitably suffer from high light(HL)stress during large-scale outdoor cultivation,resulting in photodamage and even cell death,limiting their productivity.In this review,we critically summarized recent progress on deciphering molecular mechanisms to HL and developing HL-tolerant chassis in cyanobacteria,aiming at facilitating construction of HLresistant chassis and promote the future application of the large-scale outdoor cultivation of cyanobacterial cell factories.Finally,the future directions on cyanobacterial chassis engineering were discussed.
基金Supported by The DFG,SFB638,TP A5 and SFB/TRR83,TP 13
文摘Plus-strand RNA virus replication occurs in tight association with cytoplasmic host cell membranes. Both, viral and cellular factors cooperatively generate distinct organelle-like structures, designated viral replication factories. This compartmentalization allows coordination of the different steps of the viral replication cycle, highly efficient genome replication and protection of the viral RNA from cellular defense mechanisms. Electron tomography studies conducted during the last couple of years revealed the three dimensional structure of numerous plus-strand RNA virus replication compartments and highlight morphological analogies between different virus families. Based on the morphology of virusinduced membrane rearrangements, we propose two separate subclasses: the invaginated vesicle/spherule type and the double membrane vesicle type. This review discusses common themes and distinct differences in the architecture of plus-strand RNA virus-induced membrane alterations and summarizes recent progress that has been made in understanding the complex interplay between viral and co-opted cellular factors in biogenesis and maintenance of plus-strand RNA virus replication factories.
文摘In this paper we show that the MDA can be considered as a software industrialization pattern (or a software factory). Nearly all industries today are haunted with how to reduce costs, improve quality, faster time-to-market and to maximize profits. These challenges are particularly relevant to the software industry, because it still lags behind other technology sectors as regards industrialization and the timely delivery of software products. Most software are still of poor quality, always finished after deadlines (most don’t finish at all), and are very labour intensive. Here, we discuss the MDA as an approach that may help solving at the same time both problems of industrialization and ever-changing software infrastructures. We propose a MDA Engine based on a real case study in an IT services company. It is a proposal for a framework to create custom MDA tools, based on XMI, XSLT and the Visitor Pattern.
基金supported in part by the Junior Research Group“ProMUT”(01UU1705B)which is funded by the German Federal Ministry of Education and Research as part of its funding initiative“Social-Ecological Research”the German Internet Institute(16DII116).
文摘The increasing demand for software engineers cannot completely be fulfilled by university education and conventional training approaches due to limited capacities.Accordingly,an alternative approach is necessary where potential software engineers are being educated in software engineering skills using new methods.We suggest micro tasks combined with theoretical lessons to overcome existing skill deficits and acquire fast trainable capabilities.This paper addresses the gap between demand and supply of software engineers by introducing an actionoriented and scenario-based didactical approach,which enables non-computer scientists to code.Therein,the learning content is provided in small tasks and embedded in learning factory scenarios.Therefore,different requirements for software engineers from the market side and from an academic viewpoint are analyzed and synthesized into an integrated,yet condensed skills catalogue.This enables the development of training and education units that focus on the most important skills demanded on the market.To achieve this objective,individual learning scenarios are developed.Of course,proper basic skills in coding cannot be learned over night but software programming is also no sorcery.
文摘Purpose: Leagile manufacturing is one of the time-based manufacturing practices used to improve factory performance. It is a practice that combines initiatives of Lean and agile manufacturing under certain enabling competences. Therefore, the purpose of this study is investigate the combinative nature of time-based manufacturing practices under unique enabling competences and their impact on performance of factories in Uganda. Methodology: Firstly, the underlying factor structure of competences and time-based manufacturing was examined was conducted using Principal Component Analysis (PCA). Enabling competences and time-base manufacturing practices were modelled and validated for each using confirmatory factor analysis, particularly composite reliability, average variance extracted and convergent validity. A fully fledged structural equation model was used to test the impact of leagile manufacturing on performance of factories. Findings: The study results revealed that time-based manufacturing of lean, and leagile are related but differ, in terms of their enabling competences and philosophical orientation. The findings also revealed that when small and medium factories in Uganda adopt leagile practice, they are likely not improve their performance. This is perhaps due to the fact that small and medium factories have inadequate resources. Practical Implications: The study findings shed more insights on the factors that enable adoption and implementation of time-based manufacturing practices. The extent to which these competences are orchestrated determines the benefits derived from the time-based manufacturing practices. In addition, small and medium enterprises should keenly make a choice on the appropriate practices that purposely reduce their lead time and cost of conversion. Originality: This study investigated the combinative nature of time-based manufacturing practices under unique enabling competences and their impact on performance of factories in Uganda. It is among the few studies that provide evidence on the leagile model anchored in the appropriate enabling competences in the context of developing countries. The empirical survey was done on small and medium factories to validate a leagile manufacturing model and tested its impact on factory performance.
文摘Experimentation has come a long in helping researchers achieve breakthroughs in their different scientific areas and engineering happens to be one of those areas with the most impact from experimental advancement. The need for valid experimental results free from biases and confounding conclusions has prompted the development of new experimental techniques that takes consideration of all applicable factor and combinations in providing answers on a research topic, and the Factorial Experimental design credited to Sir Ronald Fisher is one technique yielding highly valid results. This paper uses the factorial design of experiments to research the flexural impact of polyvinyl acetate fiber and layered concrete in construction. The experiment considered two levels of fiber contents and two levels of layers, and prepared samples with all combinations of the variable factors. The samples were tested after 7 days from casting for flexural strength and an advance statistical analysis was performed on the flexural responses of the samples using R-program. The results from the analyses revealed the significance of the variables to the flexural strength of the samples, as well as their interactions. The experiment concluded that based on the number of layers and fiber content used for the experiment, casting concrete in layers does have a significant negative effect on the flexural strength of concrete, and the failure pattern of concrete members under flexural load in evidently influenced by the material composition of the concrete, and that it can be evidently influenced by casting the concrete in layers.