ADVANCES OF EXPERIMENTAL RESEARCH ON ACUPUNCTURE AND MOXIBUSTION FOR TREATMENT OF WOMEN'S CLIMACTERIC SYNDROME

To introduce the advances of experimental research on acupuncture and moxibustion for treatment of Women＇s Climacteric Syndrome.The recent years experimental research literature of acupuncture and moxibustion for treatment of Women＇s Climacteric Syndrome were reviewed.The research literatures on acupuncture treatment were major,focusing on the field of acupuncture and moxibustion regulating hypothalamic-pituitary-gonad axis and nerval-endocritic-immune net.Acupuncture and moxibustion could regulate the endocrine environment of menopausal women.Taking advantage of combination biomedicine with multi-sciences,to improve the acupuncture and moxibustion curative effct and probe the mechanism of menopausal pathology and acupuncture and moxibustion function to Women＇s Climacteric Syndrome,is the research direction afterward.

Qualitative Research on Learner's Beliefs about Learning English

In the ESOL/SLA field, qualitative studies try to explain the language learning process not merely from psychological points of view, but also from social and cultural perspectives. In this study, a Chinese learner's perceptions of mainstream English instruction in China has been investigated through the interview, and the problem was explained from social and cultural perspectives.

Customization Product Design Based on User's Emotion and Needs

The paper presents a design method that ensures the ingenuity of the product form as well as the whole and exact expression of user’s needs. The key idea is to establish an automatic design system which can transform the user’s language needs into the product features in real-time. A rifle was taken as a research instance and soldiers were chosen as evaluation customers. The theory of fuzzy set and semantic difference are adopted to evaluate the relationship between user’s needs and product features as well as their alternatives. FAHP (fuzzy analytic hierarchy process) is utilized to judge the user’s satisfactory forms. This method can also be applied to other product form designs.

Use of methotrexate in inflammatory bowel disease in 2014: A User's Guide

Methotrexate has been used an immunomodulator in many autoimmune diseases,including inflammatory bowel disease. However,many physicians are unfamiliar or uncomfortable with its use in the management of inflammatory bowel disease. We summarize the data for use of methotrexate in common clinical scenarios:(1) steroid dependant Crohn's disease(CD);(2) maintenance of remission in steroid free CD;(3) azathioprine failures in CD;(4) in combination therapy with Anti-TNF agents in CD;(5) decreasing antibody formation to Anti-TNF therapy in CD;(6) management of fistulizing disease in CD; and(7) as well as induction and maintenance of remission in ulcerative colitis. An easy to use algorithm is provided for the busy clinician to access and safely prescribe methotrexate for their inflammatory bowel disease patients.

Preliminary research on myosin light chain kinase in rabbit liver

AIM: To study preliminarily the properties of myosin light chain kinase (MLCK) in rabbit liver. METHODS: The expression of MLCK was detected by reverse transcription-polymerase chain reaction(RT-PCR); the MLCK was obtained from rabbit liver, and its activity was analyzed by gamma-(32)P incorporation technique to detect the phosphorylation of myosin light chain. RESULTS: MLCK was expressed in rabbit liver, and the activity of the enzyme was similar to rabbit smooth muscle MLCK, and calmodulin-dependent. When the concentration was 0.65 mg x L(-1), the activity was at the highest level. CONCLUSION: MLCK expressed in rabbit liver may catalyze the phosphorylation of myosin light chain, which may play important roles in the regulation of hepatic cell functions.

Methodologic research on TIMP-1,TIMP-2 detection as a new diagnostic index for hepatic fibrosis and its significance

AIM: To set up a new method to detect tissue inhibitors of metalloproteinase-1 and -2(TIMP-1 and TIMP-2) in sera of patients with hepatic cirrhosis, and to investigate the expression and location of TIMP-1 and TIMP-2 in liver tissue of patients with hepatic cirrhosis, and the correlation between TIMPs in liver and those in sera so as to discuss whether TIMPs can be used as a diagnosis index of hepatic fibrosis. METHODS: The monoclonal antibodies (McAbs) of TIMP-1 and TIMP-2 were used to sensitize erythrocytes, and solid-phase absorption to sensitized erythrocytes (SPASE) was used to detect TIMP-1 and TIMP-2 in the sera of patients with hepatic cirrhosis. Meanwhile, with the method of in situ hybridization and immunohistochemistry, we studied the mRNA expression and antigen location of TIMP-1 and TIMP-2 in the livers of 40 hepatic cirrhosis patients with pathologic diagnosis. RESULTS: With SPASE, they were 16.4% higher in the acute hepatitis group, 33.3% higher in the chronic hepatitis group, and the positive rates were 73.6% and 61.2% respectively in sera of hepatic cirrhosis patients, which were remarkably higher than those in chronic hepatitis and acute hepatitis group (P【0.001). In 40 samples of hepatic cirrhosis tissues, all of them showed positive expression of TIMP-1 and TIMP-2 mRNA detected with immunohistochemistry or in situ hybridization (positive rate was 100%). Expression of TIMPs in different degrees could be found in liver tissue with cirrhosis. TIMPs were located in cytoplasm of liver cells of patients with hepatic cirrhosis. There was a significant correlation between serum TIMPs level and liver TIMPs level. CONCLUSION: SPASE is a useful method to detect the TIMP-1 and TIMP-2 in sera of patients with hepatic cirrhosis, and TIMP-1 and TIMP-2 can be considered as a useful diagnostic index of hepatic fibrosis, especially TIMP-1.

A new direction for Alzheimer's research

Despite decades of research, at present there is no curative therapy for Alzheimer＇s disease. Changes in the way new drugs are tested appear to be necessary. Three changes are presented here and will be discussed. The first change is that Alzheimer＇s disease must be considered a disease of four major pathological processes, not one. The four processes are： 1） vascular hy- poperfusion of the brain with associated mitochondrial dysfunction, 2） destructive protein inclusions, 3） uncontrolled oxidative stress, and 4） proinflammatory immune processes second- ary to microglial and astrocytic dysfunction in the brain. The second change recommended is to alter the standard cognitive measurement tools used to quantify mental decline in test patients. Specifically the Dementia Severity Rating Scale （DSRS） should supersede Mini-Mental State Examination （MMSE） and other popular tests, and a measurement scale developed in research should be used to produce a linear and non-irregular baseline. Finally, accepting the concept that four etiologies cause Alzheimer＇s disease leads to the last necessary change, that new thera- pies must be employed directed against all four causes, likely as a combination. There are drugs ready to be employed in such a combinations which are available and used clinically for other purposes so can be used ＂offlabel＂ and one such combination is suggested.

Frequent Itemset Mining of User’s Multi-Attribute under Local Differential Privacy

Frequent itemset mining is an essential problem in data mining and plays a key role in many data mining applications.However,users’personal privacy will be leaked in the mining process.In recent years,application of local differential privacy protection models to mine frequent itemsets is a relatively reliable and secure protection method.Local differential privacy means that users first perturb the original data and then send these data to the aggregator,preventing the aggregator from revealing the user’s private information.We propose a novel framework that implements frequent itemset mining under local differential privacy and is applicable to user’s multi-attribute.The main technique has bitmap encoding for converting the user’s original data into a binary string.It also includes how to choose the best perturbation algorithm for varying user attributes,and uses the frequent pattern tree(FP-tree)algorithm to mine frequent itemsets.Finally,we incorporate the threshold random response(TRR)algorithm in the framework and compare it with the existing algorithms,and demonstrate that the TRR algorithm has higher accuracy for mining frequent itemsets.

User’s Relevance of PIR System Based on Cloud Models

A new method to evaluate fuzzily user＇s relevance on the basis of cloud models has been proposed. All factors of personalized information retrieval system are taken into account in this method. So using this method for personalized information retrieval （PIR） system can efficiently judge multi-value relevance, such as quite relevant, comparatively relevant, commonly relevant, basically relevant and completely non-relevant, and realize a kind of transform of qualitative concepts and quantity and improve accuracy of relevance judgements in PIR system. Experimental data showed that the method is practical and valid. Evaluation results are more accurate and approach to the fact better.

Regulation on the Protection of Fossils Issued by the State Council of the People's Republic of China:Scientists' Researches Protected Legally—Further Explanation

With large-scale engineering projects being carried out in China, a large number of fossil localities have been discovered and excavated by responsible agencies, but still some important fossils of great value have been removed and smuggled into foreign countries. In the last three years, more than 1345 fossil specimens have been intercepted by Customs in Shenzhen, Shanghai, Tianjin, Beijing and elsewhere, and more than 5000 fossils, most of which are listed as key fossils,

英文科研文献数据库平台网站中信息构建理论的体现--以Scientific Research Publishing为例

科研文献数据库信息构建工作对于辅助科研人员开展科学研究活动具有重大现实意义。本文从组织系统、导航系统、搜索系统以及标签系统的开发入手,对以Scientific research publishing网站为代表的英文科研文献数据库网站中信息构建理论的体现进行了分析,并对英文科研文献数据库网站的信息构建工作的机遇和挑战进行了归纳。

Current Situations of Competitive Scientific Research Projects for Agri-scientific Research Institutions: A Case Study of Tropical Crops Genetic Resources Institute of Chinese Academy of Tropical Agricultural Sciences

This paper collected and arranged competitive scientific research projects undertaken by Tropical Crops Genetic Resources Institute of Chinese Academy of Tropical Agricultural Sciences in 2003-2014. Through statistical analysis on quantity of projects,funded amount,age of person responsible,professional title of person responsible,academic degree of person responsible,research object,it discussed relevant characteristics and rules. Finally,it came up with pertinent measures and recommendations,in the hope of providing services for decision-making and scientific and technological management.

Celebrating 70 years of health research on the 70^th birthday of the People's Republic of China:Outstanding Scientific Achievements by Academicians of Chinese Academy of Sciences A Chinese Academy of Engineering in Neural Regeneration

Gong Ju,Member,Chinese Academy of Sciences In 1953 Prof.Gong Ju was recruited by People’s Liberation Army to be a teacher in Department of Anatomy of the Fourth Military Medical University,a school just established and located in Xi'an,a very back-woods city.The university had little,if any,research facilities.

A Dynamic Bandwidth Allocation Solution Based on User Behavior and Software Defined EPS

For telecommunication operators, how to improve the utilization of bandwidth resources is always a problem which worthy of study, nowadays, this issue has become more and more important, since the traffic load bursting in the mobile Internet. So the key to solving this problem is that we need to find a kind of traffic model to predict the traffic load that users need. According to the predicted traffic load to allocate bandwidth to each base station dynamically.But the traffic consumption behavior of a single base station is random, it is difficult to predict[ 1 ]. For this reason, we based on reality that, when the user moves, it may get traffic load from different base stations, therefore, there will have some kind of relationship between those base stations.We use this relationship to establish a kind of Spatial Collaborative Network.consequently, we make use of stability algorithm to divided those base station cluster into different communities, According to the traffic load usage rules which these communities indicated to us, we get a traffic model.At the same time, we studied bow to use this traffic model in the future networks to dynamically allocate bandwidth resources, then we propose a new kind of EPS architecture based on SDN, on this platform, we can deploy our strategy through it＇s programmable interface.Finally, we designed an experiment to test the performance of our dynamic strategy, and the result shows that our method enables bandwidth utilization has been greatly improved.

RESEARCH REPORT ON THE GOLUB—WILKINSON’S PROBLEM

We conducted the research on the calculation of the Jordan normal form of a matrixfrom 1993 to 1998.In this period,we obtained some theoretical results,also developedand implemented a series of algorithms for the theoretical results.Now this research iscompleted to some degree.The Golub-Wilkinson’s ProblemComputing the Jordan decomposition of a matrix,introduced by G.H.Golub and J.

CHINA'S VEGETATION/ECOSYSTEM RESPONSE TO GLOBAL CHANGE: RESEARCH PROGRESS & PROSPECTS

This paper presents the latest developments in the re search progress on mechanisms by which natural plants and crops respond to the doubled concentration of CO2 in the atmosphere, resultant climatic change and the modeling of vegetation and eco-systems in China. In addition, it points out that the future study on global change and terrestrial ecosystems should stress m(?)iti-disciplinary teamwork and inter-discipline penetration. Finally, the paper emphasizes 10 research realms in the field to be enhanced in the future.

Caregiving in Alzheimer’s Disease: Research Designs &Considerations

Alzheimer’s disease and related dementias have made a considerable impact on society, and can take a significant toll on familial caregivers. Recent successful caregiving interventions suggest a promising future, though informed research design, a priori, is paramount in ensuring quality results that the Government and public may use to make informed policy and personal healthcare decisions. Research designs including basic science, randomized controlled trials (RCTs), qualitative, and quasi-experimental designs serve as the primary basis for discussion with literary examples and caveats.

Shenyang Research Institute of Foundry produces guide vane for Baihetan hydropower units with the world＇s largest unit capacity

On October 17, 2017, the first stay ring of Baihetan 1 million kW hydropower units, with the largest unit capacity in the world, passed the acceptance inspection. Shenyang Research Institute of Foundry （SRIF） has been recognized by owners and OEMs of Baihetan Hydropower Station for its long-term and stable （electroslag remelting）＂ and technology of ＂AOD ＋ ESR good performance of guide vanes at several major hydropower projects both at home and abroad.

China's Manganese Geological Research and Prospecting have Achieved Great Breakthrough

Data announced by the Chinese Ministry of Land and Resources in 2015 suggest that China has discovered more than 480 manganese ore-producing areas, with manganese ore resource reserves up to 1.22 billion tons, including 0.303 billion tons of basic reserves and 0.915 billion tons amount of resource. Among these reserves, manganese carbonate ores account for 56%, manganese oxide ores （including spongy manganese ores） accounts for 25%, and other types of manganese ore occupy 19%. Rich ores with 〉30% manganese content only account for 5% of the total resource amount, and the remaining 95% are poor manganese ores. Since 1983 when China first began to import, the imported manganese ores have increased annually by 25%. In 2001, the annual imported manganese ores reached 1.71 million tons. From 2010, the annual imported manganese ores increased by greater than 45%, reaching up to 12 million tons in 2015. Thus it seemed that the shortage of manganese ore resources will be a longterm phenomenon for China＇s economic development.

Is the 2008 financial turmoil increasing the risk of a bank run？ An empirical research in Geneva

In this paper, the authors present the results of an empirical study that attempts to analyse the risk of bank run in Geneva, Switzerland. Two similar surveys have been conducted upon two independent samples of Geneva population （June 2008 and February 2009） to detect the existence of predictive signals leading to a bank run within the selected area. The authors discover that Geneva inhabitants are generally confident in Swiss banks; the risk of a bank run in the area is low. However, reliance to the national banking system is worsening： The number of people fearing about their savings and those thinking the default of a major Swiss bank as ＂possible＂ has significantly risen. Also, more and more people keep updated about the current financial crisis; overall trust in Swiss banks has slightly decreased.