Prevalence of color vision deficiency among Chinese college students and their quality of life

AIM:To investigate the prevalence of color vision deficiency(CVD)among college students and their quality of life(QoL)in a Chinese college.METHODS:This cross-sectional study was performed in Sichuan University in Chengdu,China.The questionnaire containing participants’demographic data,as well as CVD related QoL was distributed to students who were screened as CVD[by Color Vision Examination Plates(Version 6)]in 2022 freshman entrance examination.Color blindness QoL(CBQoL)and utility analysis were used to evaluate the QoL of CVD students.RESULTS:There were 381 of 17303(2.20%)students screened as CVD,including 368(4.11%)males and 13(0.16%)females.A total of 317 students completed the questionnaire,the response rate was 83.20%.Only 166 participants(52.3%)knew they have CVD before the physical examination for college entrance examination,while a total of 145 participants(45.74%)hoped to be diagnosed earlier.The medians of CBQoL score and utility were 5.85(range 2.2-6)and 1(range 0-1),respectively.The proportions of students whose QoL is affected by CVD were 67.63%(211/312)and 42.27%(134/317)measured by CBQoL and utility analysis respectively.CONCLUSION:The prevalence of CVD in males is much higher than that in females.The time when CVD students first became aware of their CVD is relatively late.The QoL of the study population is quite high,while a large proportion of students’QoL are affected by CVD.It is suggested that as a congenital defect,CVD screening in China should be earlier,and appropriate guidance and support are needed for CVD patients to help them better adapt to life,study,and work.

Increasing Ventilation by Passive Strategies: Analysis of Indoor Air Circulation Changes through the Utilization of Microclimate Elements

A demand for renewable alternatives that would be able to deal with the problems related to well-being is directly linked to the world’s growing needs to save energy and reduce environmental costs. For a project implementation addressing these issues, it is essential to know the climatic conditions of the target area. Taking natural ventilation, climatic factors, and renewable alternatives as important sources of comfort, in this work, passive strategies, through the utilization of microclimate elements as well as the location of outside obstacles, were imposed on an initial and specific project. The objective was to introduce obstacles which could interfere in the field of external wind and evaluate whether this outside intervention is able to make changes in indoor air circulation. The wind fields for the studied cases were obtained by computational simulations, and their consequences were analyzed to attain thermal comfort. The method adopted to obtain the wind fields was a Petrov-Galerkin type method, which is a stabilized mixed finite element method of the Navier-Stokes equations considering the incompressibility and formulated in primitive variables, velocity and pressure. The obtained results point to the solutions that promote the increase or decrease of the wind-field intensity.

Economic Evaluation of Cervical Cancer Prevention Strategies in China

Objective To evaluate the economy of domestic bivalent human papilloma virus(HPV)vaccine,imported 9-valent HPV vaccine and 5 cervical cancer screening programs,and to provide a reference for relevant decision-making.Methods A Markov model of the natural disease development of cervical cancer was constructed to simulate the cumulative long-term cost and quality-adjusted life years(QALYs)of one hundred thousand healthy women after they received different interventions for cost-effectiveness analysis.Results and Conclusion Compared with the non-intervention group,the cost of per QALY obtained by two HPV vaccines and 5 screening programs ranged from 1117.56 yuan to 71660.48 yuan.Taking China’s GDP per capita in 2020 as the threshold,two HPV vaccines and 5 screening programs are cost-effective.Domestic bivalent vaccine is cost-effective and it should be introduced to the national immunization program in the future.Different screening programs are all cost-effective,too.Among them,careHPV test once every 5 years has the lowest ICER value and it can be used as the first choice for cervical cancer screening in rural areas or resource-limited areas in China.