Static Poisson’s ratio(vs)is crucial for determining geomechanical properties in petroleum applications,namely sand production.Some models have been used to predict vs;however,the published models were limited to spe...Static Poisson’s ratio(vs)is crucial for determining geomechanical properties in petroleum applications,namely sand production.Some models have been used to predict vs;however,the published models were limited to specific data ranges with an average absolute percentage relative error(AAPRE)of more than 10%.The published gated recurrent unit(GRU)models do not consider trend analysis to show physical behaviors.In this study,we aim to develop a GRU model using trend analysis and three inputs for predicting n s based on a broad range of data,n s(value of 0.1627-0.4492),bulk formation density(RHOB)(0.315-2.994 g/mL),compressional time(DTc)(44.43-186.9 μs/ft),and shear time(DTs)(72.9-341.2μ s/ft).The GRU model was evaluated using different approaches,including statistical error an-alyses.The GRU model showed the proper trends,and the model data ranges were wider than previous ones.The GRU model has the largest correlation coefficient(R)of 0.967 and the lowest AAPRE,average percent relative error(APRE),root mean square error(RMSE),and standard deviation(SD)of 3.228%,1.054%,4.389,and 0.013,respectively,compared to other models.The GRU model has a high accuracy for the different datasets:training,validation,testing,and the whole datasets with R and AAPRE values were 0.981 and 2.601%,0.966 and 3.274%,0.967 and 3.228%,and 0.977 and 2.861%,respectively.The group error analyses of all inputs show that the GRU model has less than 5% AAPRE for all input ranges,which is superior to other models that have different AAPRE values of more than 10% at various ranges of inputs.展开更多
Negative Poisson’s ratio(NPR)metamaterials are attractive for their unique mechanical behaviors and potential applications in deformation control and energy absorption.However,when subjected to significant stretching...Negative Poisson’s ratio(NPR)metamaterials are attractive for their unique mechanical behaviors and potential applications in deformation control and energy absorption.However,when subjected to significant stretching,NPR metamaterials designed under small strain assumption may experience a rapid degradation in NPR performance.To address this issue,this study aims to design metamaterials maintaining a targeted NPR under large deformation by taking advantage of the geometry nonlinearity mechanism.A representative periodic unit cell is modeled considering geometry nonlinearity,and its topology is designed using a gradient-free method.The unit cell microstructural topologies are described with the material-field series-expansion(MFSE)method.The MFSE method assumes spatial correlation of the material distribution,which greatly reduces the number of required design variables.To conveniently design metamaterials with desired NPR under large deformation,we propose a two-stage gradient-free metamaterial topology optimization method,which fully takes advantage of the dimension reduction benefits of the MFSE method and the Kriging surrogate model technique.Initially,we use homogenization to find a preliminary NPR design under a small deformation assumption.In the second stage,we begin with this preliminary design and minimize deviations in NPR from a targeted value under large deformation.Using this strategy and solution technique,we successfully obtain a group of NPR metamaterials that can sustain different desired NPRs in the range of[−0.8,−0.1]under uniaxial stretching up to 20% strain.Furthermore,typical microstructure designs are fabricated and tested through experiments.The experimental results show good consistency with our numerical results,demonstrating the effectiveness of the present gradientfree NPR metamaterial design strategy.展开更多
Wall-mounted swirling ventilation is a new type of system in mechanized excavation faces with a dust sup-pression performance that is closely related to the blowing-to-suction flow ratio.Physical and simulation models...Wall-mounted swirling ventilation is a new type of system in mechanized excavation faces with a dust sup-pression performance that is closely related to the blowing-to-suction flow ratio.Physical and simulation models were developed according to the No.C103 mechanized excavation face in the Nahe Coal Mine of the Baise Mining Bureau,Guangxi Province to optimize the blowing-to-suction flow ratio for wall-mounted swirling ventilation.Both the k-εturbulence model and the discrete phase model were utilized to simulate airflow field structures and dust concentration distribution patterns at various blowing-to-suction flow ratios.The results suggest that higher blowing-to-suction flow ratios increase the airflow field disturbance around the working face and weaken the intensity of the axial air curtain.On the other hand,both the intensity of the radial air curtain and the dust suppression effect are enhanced.At a blowing-to-suction flow ratio of 0.8,the wall-mounted swirling ventilation system achieved the most favorable dust suppression performance.Both the total dust and respirable dust had their lowest concentrations with maximum efficiencies of reducing both types at 90.33%and 87.16%,respectively.展开更多
Background: Studies have shown that pressure-controlled ventilation improves alveolar gas distribution. And inverse ratio ventilation has advantages of improving oxygenation in acute respiratory distress syndrome (ARD...Background: Studies have shown that pressure-controlled ventilation improves alveolar gas distribution. And inverse ratio ventilation has advantages of improving oxygenation in acute respiratory distress syndrome (ARDS) patients. However, the effects that pressure-controlled inverse ration ventilation in patients undergoes endotracheal intubation general anesthesia have not been assessed. Objective: To investigate whether pressure-controlled inverse ratio ventilation (PIV) would improve ventilatory and oxygenation parameters as well as lung function compared to conventional ventilation in patients undergoing open abdominal surgery. Interventions: In the conventional ventilation (CV) group, the ventilation strategy involved zero end-expiratory pressure and volume-controlled ventilation. In the pressure-controlled inverse ratio ventilation (PIV) group, the strategy involved P high starting at 7 cm H<sub>2</sub>O, P low starting at 4 cm H<sub>2</sub>O, T high at 4 s, T low at 2 s, and an inspiratory-to-expiratory time ratio of 2:1. The ΔP value was adjusted according to VT. Pressure levels were increased by 2 cm H<sub>2</sub>O until a maximal V<sub>T</sub> was observed. Inspired oxygen fraction (FIO<sub>2</sub>) was 1.0 and tidal volume (V<sub>T</sub>) was 6 mL/kg in both groups. Main Outcome Measures: The primary outcome is pulmonary function tests. Hemodynamic, ventilatory and oxygenation parameters were measured;visual analog scale (VAS) scores, and nausea and vomiting scores were also measured. Results: The PIV group tolerated pressure-controlled inverse ratio ventilation without significant hemodynamic instability. Mean airway pressure and static compliance were significantly higher in the PIV group than those in CV group (P P 2 h was well tolerated and improved respiratory compliance and lung function on the first postoperative day.展开更多
The effect of high frequency oscillatory ventilation(HFOV) at early stage on hemodynamic parameters, extravascular lung water(EVLW), lung capillary permeability, CC16 and s ICAM-1 in piglets with pulmonary or extr...The effect of high frequency oscillatory ventilation(HFOV) at early stage on hemodynamic parameters, extravascular lung water(EVLW), lung capillary permeability, CC16 and s ICAM-1 in piglets with pulmonary or extrapulmonary acute respiratory distress syndrome(ARDS) was explored. Central vein pressure(CVP) and pulse indicator continuous cardiac output(Pi CCO) were monitored in 12 anesthetized and intubated healthy piglets. Pulmonary ARDS(ARDSp) and extrapulmonary ARDS(ARDSexp) models were respectively established by lung lavage of saline solution and intravenous injection of oleic acid. Then the piglets received HFOV for 4 h. EVLW index(EVLWI), EVLW/intratroracic blood volume(ITBV) and pulmonary vascular permeability index(PVPI) were measured before and after modeling(T0 and T1), and T2(1 h), T3(2 h), T4(3 h) and T5(4 h) after HFOV. CC16 and s ICAM-1 were also detected at T1 and T5. Results showed at T1, T3, T4 and T5, EVLWI was increased more significantly in ARDSp group than in ARDSexp group(P〈0.05). The EVLWI in ARDSp group was increased at T1(P=0.008), and sustained continuously within 2 h(P=0.679, P=0.216), but decreased at T4(P=0.007) and T5(P=0.037). The EVLWI in ARDSexp group was also increased at T1(P=0.003), but significantly decreased at T3(P=0.002) and T4(P=0.019). PVPI was increased after modeling in both two groups(P=0.004, P=0.012), but there was no significant change within 4 h(T5) under HFOV in ARDSp group, while PVPI showed the increasing trends at first, then decreased in ARDSexp group after HFOV. The changes of EVLW/ITBV were similar to those of PVPI. No significant differences were found in ΔEVLWI(P=0.13), ΔPVPI(P=0.28) and ΔEVLW/ITBV between the two groups(P=0.63). The significant decreases in both CC16 and s ICAM-1 were found in both two groups 4 h after HFOV, but there was no significant difference between the two groups. It was concluded that EVLWI and lung capillary permeability were markedly increased in ARDSp and ARDSexp groups. EVLW could be decreased 4 h after the HFOV treatment. HFOV, EVLW/ITBV and PVPI were increased slightly at first, and then decreased in ARDSexp group, while in ARDSp group no significant difference was found after modeling. No significant differences were found in the decreases in EVLW and lung capillary permeability 4 h after HFOV.展开更多
In recent years,there is a scenario in urban tunnel constructions to build super-large-span tunnels for traffic diversion and route optimization purposes.However,the increased size makes tunnel support more difficult....In recent years,there is a scenario in urban tunnel constructions to build super-large-span tunnels for traffic diversion and route optimization purposes.However,the increased size makes tunnel support more difficult.Unfortunately,there are few studies on the failure and support mechanism of the surrounding rocks in the excavation of supported tunnel,while most model tests of super-large-span tunnels focus on the failure characteristics of surrounding rocks in tunnel excavation without supports.Based on excavation compensation method(ECM),model tests of a super-large-span tunnel excavation by different anchor cable support methods in the initial support stage were carried out.The results indicate that during excavation of super-large-span tunnel,the stress and displacement of the shallow surrounding rocks decrease,following a step-shape pattern,and the tunnel failure is mainly concentrated on the vault and spandrel areas.Compared with conventional anchor cable supports,the NPR(negative Poisson’s ratio)anchor cable support is more suitable for the initial support stage of the super-large-span tunnels.The tunnel support theory,model test materials,methods,and the results obtained in this study could provide references for study of similar super-large-span tunnels。展开更多
As an important indicator parameter of fluid identification,fluid factor has always been a concern for scholars.However,when predicting Russell fluid factor or effective pore-fluid bulk modulus,it is necessary to intr...As an important indicator parameter of fluid identification,fluid factor has always been a concern for scholars.However,when predicting Russell fluid factor or effective pore-fluid bulk modulus,it is necessary to introduce a new rock skeleton parameter which is the dry-rock VP/VS ratio squared(DVRS).In the process of fluid factor calculation or inversion,the existing methods take this parameter as a static constant,which has been estimated in advance,and then apply it to the fluid factor calculation and inversion.The fluid identification analysis based on a portion of the Marmousi 2 model and numerical forward modeling test show that,taking the DVRS as a static constant will limit the identification ability of fluid factor and reduce the inversion accuracy.To solve the above problems,we proposed a new method to regard the DVRS as a dynamic variable varying with depth and lithology for the first time,then apply it to fluid factor calculation and inversion.Firstly,the exact Zoeppritz equations are rewritten into a new form containing the fluid factor and DVRS of upper and lower layers.Next,the new equations are applied to the four parameters simultaneous inversion based on the generalized nonlinear inversion(GNI)method.The testing results on a portion of the Marmousi 2 model and field data show that dynamic DVRS can significantly improve the fluid factor identification ability,effectively suppress illusion.Both synthetic and filed data tests also demonstrate that the GNI method based on Bayesian deterministic inversion(BDI)theory can successfully solve the above four parameter simultaneous inversion problem,and taking the dynamic DVRS as a target inversion parameter can effectively improve the inversion accuracy of fluid factor.All these results completely verified the feasibility and effectiveness of the proposed method.展开更多
This paper assesses, through an extensive literature review, the use of ventilation and High-Efficiency Particulate Air (HEPA) purifiers as practical mitigation strategies for reducing the spread of aerosolized COVID-...This paper assesses, through an extensive literature review, the use of ventilation and High-Efficiency Particulate Air (HEPA) purifiers as practical mitigation strategies for reducing the spread of aerosolized COVID-19<sup>1</sup> virus. HEPA is a well-defined standard by the U.S. Department of Energy for filters. The focus of the literature review was on indoor air quality (IAQ) and COVID-19, with a particular emphasis on classroom settings. The start of the review, January 2020, was chosen to coincide with the first cases of COVID-19 in North America. Although children under the age of 12 are currently not yet vaccinated, there is mounting pressure for a return to normal by the start of the new school year, 2021. Also, many classrooms lack pre-installed mechanical ventilation systems (<a href="#ref79">Olsiewski et al., 2021</a>);therefore, mitigation in classrooms often falls solely in the hands of teachers and students. Research shows that ventilation and air purification are essential tools to counter aerosolized transmission (<5 μm) of the COVID-19 virus. According to <a href="#ref25">Curtius et al. (2020)</a>, the inhaled dose of particles containing virus RNA is six times lower when using air purifiers with an ACH (air changes per hour) of 5.7. However, ventilation and air purifiers are not replacements for masks, which remain vital for countering droplet (>5 μm) transmission. In addition, occupancy (i.e., number and proximity of people present in a given area) and group activity levels (e.g., talking, shouting, singing) play a critical role in viral transmission. Although natural ventilation by opening windows can be an essential strategy to help counter the spread of the virus, the level of ventilation offered by opening windows is largely uncontrollable as it is subject to weather <span style="font-family:Verdana;">conditions and building design. One must also consider the energy implications (i.e., loss of heat) that this strategy carries. Scientific evidence shows that varying levels of continuous and/or intermittent ventilation, either mechanical or natural, combined with the use of HEPA air purifiers, can provide a higher degree of protection than window access alone (<a href="#ref25">Curtius et al., 2020</a>). Systematic deployment of a hybrid mitigation strategy incorporating both ventilation and HEPA air purification in schools, offices, or other facilities offers a practical way to establish a safe re-opening of society in Canada.</span>展开更多
Bivalve shell fossils,cemented by authigenic carbonates,are widely spread in the Haima cold seep,Qiongdongnan Basin of the South China Sea(SCS).In this study,we examined an element profile of Gigantidas platifrons in ...Bivalve shell fossils,cemented by authigenic carbonates,are widely spread in the Haima cold seep,Qiongdongnan Basin of the South China Sea(SCS).In this study,we examined an element profile of Gigantidas platifrons in the Haima cold seeps at a water depth of 1381 m.Based on the scanning electron microscope(SEM)analyses,the prismatic layer and nacreous layer were identified,which are characterized by prismatic structure and stratified structure,respectively.In addition,the profile can be subdivided into two parts:altered and unaltered zones.Laser inductively coupled plasma mass spectrometry(LA-ICP-MS)mapping shows that the element concentrations of the altered zones were influenced by the authigenic carbonate rocks,whereas the element concentrations of unaltered zones remain stable.In-situ X-ray diffraction(XRD)analyses show that the mineral constituent of the prismatic layer is mainly composed of aragonite.Along with the growth profile,Mg/Ca ratios of unaltered zones have minor variations,ranging 0.72-0.97 mmol/mol(mean=0.87 mmol/mol),with estimated temperatures of 3.8-4.1℃,indicating that the temperature of the surrounding seawater remains constant and agree with the measured data of 3.9℃which was conducted by a conductivity-temperature-depth system(CTD).The minor variations of Ba/Ca ratios(0.01-0.06 mmol/mol;mean=0.04 mmol/mol)indicate a relatively stabilized salinity of the surrounding seawater.S/Ca ratios show large variations of 0.04-4.15 mmol/mol(mean=1.37 mmol/mol).S/Ca ratios have regular variations which generally correspond to the variations of the Mg/Ca ratios,highlighting that the S/Ca ratios of bivalve shells show the potential to reflect the growth rate of the Gigantides.However,further studies should be carried out on the understanding of the links between the S/Ca ratios and seepage intensity of cold-seep fluids.展开更多
Poisson’s ratio changes during the tensile stress of technical fabric samples due to the anisotropy of technical fabrics.This paper examines the effects of the type of weave and the anisotropic characteristics of the...Poisson’s ratio changes during the tensile stress of technical fabric samples due to the anisotropy of technical fabrics.This paper examines the effects of the type of weave and the anisotropic characteristics of the technical fabric on maximum tensile force,corresponding elongation,work-to-maximum force,elasticity modulus,and Poisson’s ratio when axial tensile forces are applied to samples cut at various angles in the direction of the weft yarns of the technical fabric.In the lab,3 cotton fabric samples of constant warp and weft density with different structural weave types(plain weave,twill weave,atlas weave)were subjected to the tensile force until they broke at the following angles:0°,15°,30°,45°,60°,75°,90°.Based on the different measured values of technical fabric stretching in the longitudinal direction and lateral narrowing,Poisson’s ratio is calculated.The Poisson’s ratio was calculated up to a relative elongation of the fabric of 8%,as the buckling of the fabric occurs according to this elongation value.According to the results presented in this paper,the type of weave of the fabric,the direction of tensile force,and the relative narrowing of the technical fabrics all play important roles in the Poisson’s ratio value.The Poisson’s ratio curve of a technical fabric under tensile stress(i.e.elongation)is primarily determined by its behaviour in the opposite direction of the elongation.The change in the value of the Poisson’s ratio is represented by a graph that first increases nonlinearly and then decreases after reaching its maximum value.展开更多
The experiment was conducted at Veterinary Research Station of Faculty of Veterinary Medicine,Royal University of Agriculture.The experimental period lasted 60 days,starting from October 1st to November 30th 2022.CRD(...The experiment was conducted at Veterinary Research Station of Faculty of Veterinary Medicine,Royal University of Agriculture.The experimental period lasted 60 days,starting from October 1st to November 30th 2022.CRD(Completely Randomized Design)was used with 2 treatments/groups,vaccination group and non-vaccination group“control”,and 6 replications.The vaccination groups received two times of vaccination by dropping into the ocular at 7 days and 21 days.Meanwhile,blood samples were collected 3 times to detect the antibody level of ND(Newcastle Disease)and contained 21 days old,35 days old and 49 days old chicks.The ELISA(Enzyme-Linked Immunosorbent Assay)was performed to detect the antibody of those 2 groups.The result of finding showed that the S/P(Sample to Positive)ratio of control at 21 days,was very low,even in 3rd quartile,which was below the threshold.However,the vaccination group was relatively high,even in 1st quartile,which was higher than the threshold.At 35 days,S/P ratio of control group was still very low,but a bit higher than at 21 days.Meanwhile,the vaccination group was still high,even in 1st quartile,and two-time higher than at 21 days,but an increasing number of samples developed less antibody than threshold,accounting for 12.22%.At 49 days,the control group was still very low,even in 3rd quartile,but a bit higher than at 21 days and 35 days,and was close to the threshold.The vaccination group was still relatively high,even in 1st quartile but lower than three times comparing to 35 days.However,in this age,the number of chickens that developed antibody seemed to be increased in the control group,vice versa for vaccination group.The average S/P ratio was different significant(p<0.001),where vaccination had higher S/P ratio than control.It was similar finding for log-titer,the vaccination had higher figure(p<0.001).The risk of infection of ND was higher in control group,but it will reduce by increasing the age of chicken,while vaccination group was decreased by increasing age,especially at 49 days and we need to consider another vaccination to get full protection.展开更多
基金The authors thank the Yayasan Universiti Teknologi PETRONAS(YUTP FRG Grant No.015LC0-428)at Universiti Teknologi PETRO-NAS for supporting this study.
文摘Static Poisson’s ratio(vs)is crucial for determining geomechanical properties in petroleum applications,namely sand production.Some models have been used to predict vs;however,the published models were limited to specific data ranges with an average absolute percentage relative error(AAPRE)of more than 10%.The published gated recurrent unit(GRU)models do not consider trend analysis to show physical behaviors.In this study,we aim to develop a GRU model using trend analysis and three inputs for predicting n s based on a broad range of data,n s(value of 0.1627-0.4492),bulk formation density(RHOB)(0.315-2.994 g/mL),compressional time(DTc)(44.43-186.9 μs/ft),and shear time(DTs)(72.9-341.2μ s/ft).The GRU model was evaluated using different approaches,including statistical error an-alyses.The GRU model showed the proper trends,and the model data ranges were wider than previous ones.The GRU model has the largest correlation coefficient(R)of 0.967 and the lowest AAPRE,average percent relative error(APRE),root mean square error(RMSE),and standard deviation(SD)of 3.228%,1.054%,4.389,and 0.013,respectively,compared to other models.The GRU model has a high accuracy for the different datasets:training,validation,testing,and the whole datasets with R and AAPRE values were 0.981 and 2.601%,0.966 and 3.274%,0.967 and 3.228%,and 0.977 and 2.861%,respectively.The group error analyses of all inputs show that the GRU model has less than 5% AAPRE for all input ranges,which is superior to other models that have different AAPRE values of more than 10% at various ranges of inputs.
基金the support of the National Science Foundation of China(12372120,12172075)the Liaoning Revitalization Talents Program(XLYC2007027)Fundamental Research Funds for the Central Universities(DUT21RC(3)067).
文摘Negative Poisson’s ratio(NPR)metamaterials are attractive for their unique mechanical behaviors and potential applications in deformation control and energy absorption.However,when subjected to significant stretching,NPR metamaterials designed under small strain assumption may experience a rapid degradation in NPR performance.To address this issue,this study aims to design metamaterials maintaining a targeted NPR under large deformation by taking advantage of the geometry nonlinearity mechanism.A representative periodic unit cell is modeled considering geometry nonlinearity,and its topology is designed using a gradient-free method.The unit cell microstructural topologies are described with the material-field series-expansion(MFSE)method.The MFSE method assumes spatial correlation of the material distribution,which greatly reduces the number of required design variables.To conveniently design metamaterials with desired NPR under large deformation,we propose a two-stage gradient-free metamaterial topology optimization method,which fully takes advantage of the dimension reduction benefits of the MFSE method and the Kriging surrogate model technique.Initially,we use homogenization to find a preliminary NPR design under a small deformation assumption.In the second stage,we begin with this preliminary design and minimize deviations in NPR from a targeted value under large deformation.Using this strategy and solution technique,we successfully obtain a group of NPR metamaterials that can sustain different desired NPRs in the range of[−0.8,−0.1]under uniaxial stretching up to 20% strain.Furthermore,typical microstructure designs are fabricated and tested through experiments.The experimental results show good consistency with our numerical results,demonstrating the effectiveness of the present gradientfree NPR metamaterial design strategy.
基金support for this work was provided by the National Natural Science Foundation of China(No.51574123)the Scientific Research Project of Hunan Province Office of Education(No.18A185),which are gratefully acknowledged.
文摘Wall-mounted swirling ventilation is a new type of system in mechanized excavation faces with a dust sup-pression performance that is closely related to the blowing-to-suction flow ratio.Physical and simulation models were developed according to the No.C103 mechanized excavation face in the Nahe Coal Mine of the Baise Mining Bureau,Guangxi Province to optimize the blowing-to-suction flow ratio for wall-mounted swirling ventilation.Both the k-εturbulence model and the discrete phase model were utilized to simulate airflow field structures and dust concentration distribution patterns at various blowing-to-suction flow ratios.The results suggest that higher blowing-to-suction flow ratios increase the airflow field disturbance around the working face and weaken the intensity of the axial air curtain.On the other hand,both the intensity of the radial air curtain and the dust suppression effect are enhanced.At a blowing-to-suction flow ratio of 0.8,the wall-mounted swirling ventilation system achieved the most favorable dust suppression performance.Both the total dust and respirable dust had their lowest concentrations with maximum efficiencies of reducing both types at 90.33%and 87.16%,respectively.
文摘Background: Studies have shown that pressure-controlled ventilation improves alveolar gas distribution. And inverse ratio ventilation has advantages of improving oxygenation in acute respiratory distress syndrome (ARDS) patients. However, the effects that pressure-controlled inverse ration ventilation in patients undergoes endotracheal intubation general anesthesia have not been assessed. Objective: To investigate whether pressure-controlled inverse ratio ventilation (PIV) would improve ventilatory and oxygenation parameters as well as lung function compared to conventional ventilation in patients undergoing open abdominal surgery. Interventions: In the conventional ventilation (CV) group, the ventilation strategy involved zero end-expiratory pressure and volume-controlled ventilation. In the pressure-controlled inverse ratio ventilation (PIV) group, the strategy involved P high starting at 7 cm H<sub>2</sub>O, P low starting at 4 cm H<sub>2</sub>O, T high at 4 s, T low at 2 s, and an inspiratory-to-expiratory time ratio of 2:1. The ΔP value was adjusted according to VT. Pressure levels were increased by 2 cm H<sub>2</sub>O until a maximal V<sub>T</sub> was observed. Inspired oxygen fraction (FIO<sub>2</sub>) was 1.0 and tidal volume (V<sub>T</sub>) was 6 mL/kg in both groups. Main Outcome Measures: The primary outcome is pulmonary function tests. Hemodynamic, ventilatory and oxygenation parameters were measured;visual analog scale (VAS) scores, and nausea and vomiting scores were also measured. Results: The PIV group tolerated pressure-controlled inverse ratio ventilation without significant hemodynamic instability. Mean airway pressure and static compliance were significantly higher in the PIV group than those in CV group (P P 2 h was well tolerated and improved respiratory compliance and lung function on the first postoperative day.
文摘The effect of high frequency oscillatory ventilation(HFOV) at early stage on hemodynamic parameters, extravascular lung water(EVLW), lung capillary permeability, CC16 and s ICAM-1 in piglets with pulmonary or extrapulmonary acute respiratory distress syndrome(ARDS) was explored. Central vein pressure(CVP) and pulse indicator continuous cardiac output(Pi CCO) were monitored in 12 anesthetized and intubated healthy piglets. Pulmonary ARDS(ARDSp) and extrapulmonary ARDS(ARDSexp) models were respectively established by lung lavage of saline solution and intravenous injection of oleic acid. Then the piglets received HFOV for 4 h. EVLW index(EVLWI), EVLW/intratroracic blood volume(ITBV) and pulmonary vascular permeability index(PVPI) were measured before and after modeling(T0 and T1), and T2(1 h), T3(2 h), T4(3 h) and T5(4 h) after HFOV. CC16 and s ICAM-1 were also detected at T1 and T5. Results showed at T1, T3, T4 and T5, EVLWI was increased more significantly in ARDSp group than in ARDSexp group(P〈0.05). The EVLWI in ARDSp group was increased at T1(P=0.008), and sustained continuously within 2 h(P=0.679, P=0.216), but decreased at T4(P=0.007) and T5(P=0.037). The EVLWI in ARDSexp group was also increased at T1(P=0.003), but significantly decreased at T3(P=0.002) and T4(P=0.019). PVPI was increased after modeling in both two groups(P=0.004, P=0.012), but there was no significant change within 4 h(T5) under HFOV in ARDSp group, while PVPI showed the increasing trends at first, then decreased in ARDSexp group after HFOV. The changes of EVLW/ITBV were similar to those of PVPI. No significant differences were found in ΔEVLWI(P=0.13), ΔPVPI(P=0.28) and ΔEVLW/ITBV between the two groups(P=0.63). The significant decreases in both CC16 and s ICAM-1 were found in both two groups 4 h after HFOV, but there was no significant difference between the two groups. It was concluded that EVLWI and lung capillary permeability were markedly increased in ARDSp and ARDSexp groups. EVLW could be decreased 4 h after the HFOV treatment. HFOV, EVLW/ITBV and PVPI were increased slightly at first, and then decreased in ARDSexp group, while in ARDSp group no significant difference was found after modeling. No significant differences were found in the decreases in EVLW and lung capillary permeability 4 h after HFOV.
基金supported by the Innovation Fund Research Project of State Key Laboratory for Geomechanics and Deep Underground Engineering,China University of Mining and Technology(Grant No.SKLGDUEK202201)the Foundation for the Opening of State Key Laboratory for Geomechanics and Deep Underground Engineering,China University of Mining and Technology(Grant No.SKLGDUEK2129)the Open Research Fund of State Key Laboratory of Geomechanics and Geotechnical Engineering,Institute of Rock and Soil Mechanics,Chinese Academy of Sciences(Grant No.Z020007)。
文摘In recent years,there is a scenario in urban tunnel constructions to build super-large-span tunnels for traffic diversion and route optimization purposes.However,the increased size makes tunnel support more difficult.Unfortunately,there are few studies on the failure and support mechanism of the surrounding rocks in the excavation of supported tunnel,while most model tests of super-large-span tunnels focus on the failure characteristics of surrounding rocks in tunnel excavation without supports.Based on excavation compensation method(ECM),model tests of a super-large-span tunnel excavation by different anchor cable support methods in the initial support stage were carried out.The results indicate that during excavation of super-large-span tunnel,the stress and displacement of the shallow surrounding rocks decrease,following a step-shape pattern,and the tunnel failure is mainly concentrated on the vault and spandrel areas.Compared with conventional anchor cable supports,the NPR(negative Poisson’s ratio)anchor cable support is more suitable for the initial support stage of the super-large-span tunnels.The tunnel support theory,model test materials,methods,and the results obtained in this study could provide references for study of similar super-large-span tunnels。
基金the National Natural Science Foundation of China(41904116,41874156,42074167 and 42204135)the Natural Science Foundation of Hunan Province(2020JJ5168)the China Postdoctoral Science Foundation(2021M703629)for their funding of this research.
文摘As an important indicator parameter of fluid identification,fluid factor has always been a concern for scholars.However,when predicting Russell fluid factor or effective pore-fluid bulk modulus,it is necessary to introduce a new rock skeleton parameter which is the dry-rock VP/VS ratio squared(DVRS).In the process of fluid factor calculation or inversion,the existing methods take this parameter as a static constant,which has been estimated in advance,and then apply it to the fluid factor calculation and inversion.The fluid identification analysis based on a portion of the Marmousi 2 model and numerical forward modeling test show that,taking the DVRS as a static constant will limit the identification ability of fluid factor and reduce the inversion accuracy.To solve the above problems,we proposed a new method to regard the DVRS as a dynamic variable varying with depth and lithology for the first time,then apply it to fluid factor calculation and inversion.Firstly,the exact Zoeppritz equations are rewritten into a new form containing the fluid factor and DVRS of upper and lower layers.Next,the new equations are applied to the four parameters simultaneous inversion based on the generalized nonlinear inversion(GNI)method.The testing results on a portion of the Marmousi 2 model and field data show that dynamic DVRS can significantly improve the fluid factor identification ability,effectively suppress illusion.Both synthetic and filed data tests also demonstrate that the GNI method based on Bayesian deterministic inversion(BDI)theory can successfully solve the above four parameter simultaneous inversion problem,and taking the dynamic DVRS as a target inversion parameter can effectively improve the inversion accuracy of fluid factor.All these results completely verified the feasibility and effectiveness of the proposed method.
文摘This paper assesses, through an extensive literature review, the use of ventilation and High-Efficiency Particulate Air (HEPA) purifiers as practical mitigation strategies for reducing the spread of aerosolized COVID-19<sup>1</sup> virus. HEPA is a well-defined standard by the U.S. Department of Energy for filters. The focus of the literature review was on indoor air quality (IAQ) and COVID-19, with a particular emphasis on classroom settings. The start of the review, January 2020, was chosen to coincide with the first cases of COVID-19 in North America. Although children under the age of 12 are currently not yet vaccinated, there is mounting pressure for a return to normal by the start of the new school year, 2021. Also, many classrooms lack pre-installed mechanical ventilation systems (<a href="#ref79">Olsiewski et al., 2021</a>);therefore, mitigation in classrooms often falls solely in the hands of teachers and students. Research shows that ventilation and air purification are essential tools to counter aerosolized transmission (<5 μm) of the COVID-19 virus. According to <a href="#ref25">Curtius et al. (2020)</a>, the inhaled dose of particles containing virus RNA is six times lower when using air purifiers with an ACH (air changes per hour) of 5.7. However, ventilation and air purifiers are not replacements for masks, which remain vital for countering droplet (>5 μm) transmission. In addition, occupancy (i.e., number and proximity of people present in a given area) and group activity levels (e.g., talking, shouting, singing) play a critical role in viral transmission. Although natural ventilation by opening windows can be an essential strategy to help counter the spread of the virus, the level of ventilation offered by opening windows is largely uncontrollable as it is subject to weather <span style="font-family:Verdana;">conditions and building design. One must also consider the energy implications (i.e., loss of heat) that this strategy carries. Scientific evidence shows that varying levels of continuous and/or intermittent ventilation, either mechanical or natural, combined with the use of HEPA air purifiers, can provide a higher degree of protection than window access alone (<a href="#ref25">Curtius et al., 2020</a>). Systematic deployment of a hybrid mitigation strategy incorporating both ventilation and HEPA air purification in schools, offices, or other facilities offers a practical way to establish a safe re-opening of society in Canada.</span>
基金Supported by the Key Research and Development Project of Guangdong Province(No.2020B1111510001)the National Natural Science Foundation of China(No.U2244224)+1 种基金the PI Project of Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou)(No.GML2020GD0802)the Guangdong Special Support Team Program(No.2019BT02H594)。
文摘Bivalve shell fossils,cemented by authigenic carbonates,are widely spread in the Haima cold seep,Qiongdongnan Basin of the South China Sea(SCS).In this study,we examined an element profile of Gigantidas platifrons in the Haima cold seeps at a water depth of 1381 m.Based on the scanning electron microscope(SEM)analyses,the prismatic layer and nacreous layer were identified,which are characterized by prismatic structure and stratified structure,respectively.In addition,the profile can be subdivided into two parts:altered and unaltered zones.Laser inductively coupled plasma mass spectrometry(LA-ICP-MS)mapping shows that the element concentrations of the altered zones were influenced by the authigenic carbonate rocks,whereas the element concentrations of unaltered zones remain stable.In-situ X-ray diffraction(XRD)analyses show that the mineral constituent of the prismatic layer is mainly composed of aragonite.Along with the growth profile,Mg/Ca ratios of unaltered zones have minor variations,ranging 0.72-0.97 mmol/mol(mean=0.87 mmol/mol),with estimated temperatures of 3.8-4.1℃,indicating that the temperature of the surrounding seawater remains constant and agree with the measured data of 3.9℃which was conducted by a conductivity-temperature-depth system(CTD).The minor variations of Ba/Ca ratios(0.01-0.06 mmol/mol;mean=0.04 mmol/mol)indicate a relatively stabilized salinity of the surrounding seawater.S/Ca ratios show large variations of 0.04-4.15 mmol/mol(mean=1.37 mmol/mol).S/Ca ratios have regular variations which generally correspond to the variations of the Mg/Ca ratios,highlighting that the S/Ca ratios of bivalve shells show the potential to reflect the growth rate of the Gigantides.However,further studies should be carried out on the understanding of the links between the S/Ca ratios and seepage intensity of cold-seep fluids.
文摘Poisson’s ratio changes during the tensile stress of technical fabric samples due to the anisotropy of technical fabrics.This paper examines the effects of the type of weave and the anisotropic characteristics of the technical fabric on maximum tensile force,corresponding elongation,work-to-maximum force,elasticity modulus,and Poisson’s ratio when axial tensile forces are applied to samples cut at various angles in the direction of the weft yarns of the technical fabric.In the lab,3 cotton fabric samples of constant warp and weft density with different structural weave types(plain weave,twill weave,atlas weave)were subjected to the tensile force until they broke at the following angles:0°,15°,30°,45°,60°,75°,90°.Based on the different measured values of technical fabric stretching in the longitudinal direction and lateral narrowing,Poisson’s ratio is calculated.The Poisson’s ratio was calculated up to a relative elongation of the fabric of 8%,as the buckling of the fabric occurs according to this elongation value.According to the results presented in this paper,the type of weave of the fabric,the direction of tensile force,and the relative narrowing of the technical fabrics all play important roles in the Poisson’s ratio value.The Poisson’s ratio curve of a technical fabric under tensile stress(i.e.elongation)is primarily determined by its behaviour in the opposite direction of the elongation.The change in the value of the Poisson’s ratio is represented by a graph that first increases nonlinearly and then decreases after reaching its maximum value.
文摘The experiment was conducted at Veterinary Research Station of Faculty of Veterinary Medicine,Royal University of Agriculture.The experimental period lasted 60 days,starting from October 1st to November 30th 2022.CRD(Completely Randomized Design)was used with 2 treatments/groups,vaccination group and non-vaccination group“control”,and 6 replications.The vaccination groups received two times of vaccination by dropping into the ocular at 7 days and 21 days.Meanwhile,blood samples were collected 3 times to detect the antibody level of ND(Newcastle Disease)and contained 21 days old,35 days old and 49 days old chicks.The ELISA(Enzyme-Linked Immunosorbent Assay)was performed to detect the antibody of those 2 groups.The result of finding showed that the S/P(Sample to Positive)ratio of control at 21 days,was very low,even in 3rd quartile,which was below the threshold.However,the vaccination group was relatively high,even in 1st quartile,which was higher than the threshold.At 35 days,S/P ratio of control group was still very low,but a bit higher than at 21 days.Meanwhile,the vaccination group was still high,even in 1st quartile,and two-time higher than at 21 days,but an increasing number of samples developed less antibody than threshold,accounting for 12.22%.At 49 days,the control group was still very low,even in 3rd quartile,but a bit higher than at 21 days and 35 days,and was close to the threshold.The vaccination group was still relatively high,even in 1st quartile but lower than three times comparing to 35 days.However,in this age,the number of chickens that developed antibody seemed to be increased in the control group,vice versa for vaccination group.The average S/P ratio was different significant(p<0.001),where vaccination had higher S/P ratio than control.It was similar finding for log-titer,the vaccination had higher figure(p<0.001).The risk of infection of ND was higher in control group,but it will reduce by increasing the age of chicken,while vaccination group was decreased by increasing age,especially at 49 days and we need to consider another vaccination to get full protection.