Tinnitus is the perception of a monotonous sound not present in the environment. Nearly 20% of the U.S. population suffers from tinnitus, and tinnitus has been reported to be the most prevalent service-connected disab...Tinnitus is the perception of a monotonous sound not present in the environment. Nearly 20% of the U.S. population suffers from tinnitus, and tinnitus has been reported to be the most prevalent service-connected disability of all U.S. veterans （Henry et al., 2005; Eggermont, 2012; Veterans Benefits Administration, 2014）. Many types of peripheral injury have been understood to induce tinnitus, including damage to the cochlea by intense sound or ototoxic medications and destruction of the auditory nerve by cochlear ablation or nerve transection （Lee and God- frey, 2014）. The pathophysiological mechanisms by which tin- nitus develops are only poorly understood. In order to further clarify the pathogenesis, a need has been expressed for a better understanding of the rebalancing of excitatory and inhibitory signaling mechanisms that occur after peripheral injury （Gold and Bajo, 2014）. One of the current, prominent hypotheses of tinnitus development is that, after being triggered by peripheral injury, tinnitus may result from a maladaptation of the central auditory system to this peripheral dysfunction （Auerbach et al., 2014）, and that one of the mechanisms by which this occurs is a decrease in inhibitory neurotransmission. The major struc- tures that play a role in transmitting neural activity through the ascending central auditory system include the cochlear nucleus and superior olivary complex of the pons-medulla region, the inferior colliculus of the midbrain, the medial geniculate nude- us of the thalamus, and the auditory cortex.展开更多
Time Asia magazine has again released its November appraisal issue of “Asian heroes” who have helped shape the continent’s future over the past 60 years. The Chinese on the list, most of whom are very familiar to t...Time Asia magazine has again released its November appraisal issue of “Asian heroes” who have helped shape the continent’s future over the past 60 years. The Chinese on the list, most of whom are very familiar to their countrymen, have sparked a great sensation in the whole nation. Wen Dao, a Beijing-based observer, looks at the profound changes in Westerners’ comprehension of China over the past decades and shares his expectations for the future.展开更多
At least zoologists know that barnacles are arthropods rather than mollusks.However,this knowledge is surprisingly new,for it was as recent as 1830 before J.Vaughan Thompson showed,through a careful study of barnacle ...At least zoologists know that barnacles are arthropods rather than mollusks.However,this knowledge is surprisingly new,for it was as recent as 1830 before J.Vaughan Thompson showed,through a careful study of barnacle larvae,that they were crustaceans.In the 1850s,Charles Darwin unraveled much of the taxonomy of barnacles,and,significantly,his observations and classification of them follow the structure that was to be published later as his evolutionary theory.Irrespective of these works,knowledge of the systematic placement of barnacles remains surprisingly poor in the wider population today,with most non-biologists viewing barnacles as shallow-water fouling organisms related to oysters and limpets.The present paper reviews the way humans have perceived barnacles for at least a millennium;it evaluates why they were thought to have grown from trees and to have been part of the life cycle of birds;it concludes by contemplating the manner in which we perceive our environment and by doing so try to make sense of our world.展开更多
This article analyzes two literary works by the Czech writer, Julius Zeyer （1841-1901）, and Lu Xun （1881-1936） by elaborating upon two different myths concerning the Archer Hou Yi. These myths were presented by th...This article analyzes two literary works by the Czech writer, Julius Zeyer （1841-1901）, and Lu Xun （1881-1936） by elaborating upon two different myths concerning the Archer Hou Yi. These myths were presented by the missionary and Sinologist William Frederick Mayers in The Chinese Reader＇s Manual： A Handbook of Biographical, Historical, Mythological and General Literary References （1874）, and other Chinese sources. Zeyer highlighted the first myth, which was connected with the Emperor Yao and showed Hou Yi shooting arrows at the nine suns appearing together in the heavens, and Lu Xun preferred the second myth, where the Archer Yi rebelled against the Emperor Tai Kang, whom he drove from the Capital, and later was killed by Han Zhuo. The myth of Chang E who flew to the moon is described only by Lu Xun.展开更多
基金received from the University of Toledo Foundationthe American Tinnitus Association
文摘Tinnitus is the perception of a monotonous sound not present in the environment. Nearly 20% of the U.S. population suffers from tinnitus, and tinnitus has been reported to be the most prevalent service-connected disability of all U.S. veterans （Henry et al., 2005; Eggermont, 2012; Veterans Benefits Administration, 2014）. Many types of peripheral injury have been understood to induce tinnitus, including damage to the cochlea by intense sound or ototoxic medications and destruction of the auditory nerve by cochlear ablation or nerve transection （Lee and God- frey, 2014）. The pathophysiological mechanisms by which tin- nitus develops are only poorly understood. In order to further clarify the pathogenesis, a need has been expressed for a better understanding of the rebalancing of excitatory and inhibitory signaling mechanisms that occur after peripheral injury （Gold and Bajo, 2014）. One of the current, prominent hypotheses of tinnitus development is that, after being triggered by peripheral injury, tinnitus may result from a maladaptation of the central auditory system to this peripheral dysfunction （Auerbach et al., 2014）, and that one of the mechanisms by which this occurs is a decrease in inhibitory neurotransmission. The major struc- tures that play a role in transmitting neural activity through the ascending central auditory system include the cochlear nucleus and superior olivary complex of the pons-medulla region, the inferior colliculus of the midbrain, the medial geniculate nude- us of the thalamus, and the auditory cortex.
文摘Time Asia magazine has again released its November appraisal issue of “Asian heroes” who have helped shape the continent’s future over the past 60 years. The Chinese on the list, most of whom are very familiar to their countrymen, have sparked a great sensation in the whole nation. Wen Dao, a Beijing-based observer, looks at the profound changes in Westerners’ comprehension of China over the past decades and shares his expectations for the future.
基金I thank Professor William(Bill)A.Newman,Scripps Institute of Oceanography,California,my constant friend in the Cirripedia,who has mentored,debated and researched with me on barnacles for more than 3 decades.It was in the 1990s that Bill directed me to the extraordinary work of the English polymath Edward Heron-Allen,whose observations feature significantly in this paper.Professor Rob Watts and Father Jo Dirks,RMIT University,Melbourne,Associate Professor James McGrath,Butler University,Indianapolis provided helpful comments at an early stage of the manuscript and 3 anonymous referees provided further insight,Ms Urara“Fujitsubo”Kuratani,of Kobe,Japan kindly provided images of her wonderful barnacle art,demonstrating that cirripedophilia is alive and thriving in the 21st century.Ms Sandra Powlette,British Library,London is thanked for kindly arranging permission,without fee,to use the image in Fig.1(taken from the 13th century manuscript Bestiary).I also thank the Bureau of International Cooperation,Chinese Academy of Sciences that supported my attendance at the Seventh International Crustacean Congress in Qingdao,China,to give an oral presentation of this paper.
文摘At least zoologists know that barnacles are arthropods rather than mollusks.However,this knowledge is surprisingly new,for it was as recent as 1830 before J.Vaughan Thompson showed,through a careful study of barnacle larvae,that they were crustaceans.In the 1850s,Charles Darwin unraveled much of the taxonomy of barnacles,and,significantly,his observations and classification of them follow the structure that was to be published later as his evolutionary theory.Irrespective of these works,knowledge of the systematic placement of barnacles remains surprisingly poor in the wider population today,with most non-biologists viewing barnacles as shallow-water fouling organisms related to oysters and limpets.The present paper reviews the way humans have perceived barnacles for at least a millennium;it evaluates why they were thought to have grown from trees and to have been part of the life cycle of birds;it concludes by contemplating the manner in which we perceive our environment and by doing so try to make sense of our world.
文摘This article analyzes two literary works by the Czech writer, Julius Zeyer （1841-1901）, and Lu Xun （1881-1936） by elaborating upon two different myths concerning the Archer Hou Yi. These myths were presented by the missionary and Sinologist William Frederick Mayers in The Chinese Reader＇s Manual： A Handbook of Biographical, Historical, Mythological and General Literary References （1874）, and other Chinese sources. Zeyer highlighted the first myth, which was connected with the Emperor Yao and showed Hou Yi shooting arrows at the nine suns appearing together in the heavens, and Lu Xun preferred the second myth, where the Archer Yi rebelled against the Emperor Tai Kang, whom he drove from the Capital, and later was killed by Han Zhuo. The myth of Chang E who flew to the moon is described only by Lu Xun.
