Epilepsy can be defined as a dysfunction of the brain network,and each type of epilepsy involves different brain-network changes that are implicated diffe rently in the control and propagation of interictal or ictal d...Epilepsy can be defined as a dysfunction of the brain network,and each type of epilepsy involves different brain-network changes that are implicated diffe rently in the control and propagation of interictal or ictal discharges.Gaining more detailed information on brain network alterations can help us to further understand the mechanisms of epilepsy and pave the way for brain network-based precise therapeutic approaches in clinical practice.An increasing number of advanced neuroimaging techniques and electrophysiological techniques such as diffusion tensor imaging-based fiber tra ctography,diffusion kurtosis imaging-based fiber tractography,fiber ball imagingbased tra ctography,electroencephalography,functional magnetic resonance imaging,magnetoencephalography,positron emission tomography,molecular imaging,and functional ultrasound imaging have been extensively used to delineate epileptic networks.In this review,we summarize the relevant neuroimaging and neuroelectrophysiological techniques for assessing structural and functional brain networks in patients with epilepsy,and extensively analyze the imaging mechanisms,advantages,limitations,and clinical application ranges of each technique.A greater focus on emerging advanced technologies,new data analysis software,a combination of multiple techniques,and the construction of personalized virtual epilepsy models can provide a theoretical basis to better understand the brain network mechanisms of epilepsy and make surgical decisions.展开更多
With the advent of the information age, people＇ s lives have been changed unknowingly owing to lots of modem technology means. For the environmental artistic design, the traditional mode of environmental artistic des...With the advent of the information age, people＇ s lives have been changed unknowingly owing to lots of modem technology means. For the environmental artistic design, the traditional mode of environmental artistic design is broken through after the emergence of computer technology and virtual reality technique, which makes the scheme and application of virtual reality technique in environmental artistic design to own more practical value. In this paper, the virtual reality technique and its practical application in environmental artistic design are set forth, and the profound influence on the actual design by the virtual reality technique is studied with expectation of enlightenment for broadening the thought of environmental artistic design.展开更多
The virtual technique in Chinese drama makes the aesthetic feeling of the audiences enriched in enjoying the art of stage performance to their heart＇s content when the reality of life is reflected by drama. Also, the...The virtual technique in Chinese drama makes the aesthetic feeling of the audiences enriched in enjoying the art of stage performance to their heart＇s content when the reality of life is reflected by drama. Also, the position of the animation art has been promoted by the expression and extension of the drama art spirit and expression technique in the creation of film and television animations to be greatly improved. In this paper, the characteristics of the virtual technique in drama are briefly introduced, and also the influence of the virtual technique on the creation offihn and television animations is analyzed.展开更多
Twenty years after its introduction, computed tomographic colonography (CTC) has reached its maturity, and it can reasonably be considered the best radiological diagnostic test for imaging colorectal cancer (CRC) and ...Twenty years after its introduction, computed tomographic colonography (CTC) has reached its maturity, and it can reasonably be considered the best radiological diagnostic test for imaging colorectal cancer (CRC) and polyps. This examination technique is less invasive than colonoscopy (CS), easy to perform, and standardized. Reduced bowel preparation and colonic distention using carbon dioxide favor patient compliance. Widespread implementation of a new image reconstruction algorithm has minimized radiation exposure, and the use of dedicated software with enhanced views has enabled easier image interpretation. Integration in the routine workflow of a computer-aided detection algorithm reduces perceptual errors, particularly for small polyps. Consolidated evidence from the literature shows that the diagnostic performances for the detection of CRC and large polyps in symptomatic and asymptomatic individuals are similar to CS and are largely superior to barium enema, the latter of which should be strongly discouraged. Favorable data regarding CTC performance open the possibility for many different indications, some of which are already supported by evidence-based data: incomplete, failed, or unfeasible CS; symptomatic, elderly, and frail patients; and investigation of diverticular disease. Other indications are still being debated and, thus, are recommended only if CS is unfeasible: the use of CTC in CRC screening and in surveillance after surgery for CRC or polypectomy. In order for CTC to be used appropriately, contraindications such as acute abdominal conditions (diverticulitis or the acute phase of inflammatory bowel diseases) and surveillance in patients with a long-standing history of ulcerative colitis or Crohn’s disease and in those with hereditary colonic syndromes should not be overlooked. This will maximize the benefits of the technique and minimize potential sources of frustration or disappointment for both referring clinicians and patients.展开更多
We compared DVHs （dose volume histograms） of two tangential irradiation techniques for whole breast RT （radiotherapy） CT （computed tomography） based 2D （two dimensional） technique with wedge filters and 3D CRT...We compared DVHs （dose volume histograms） of two tangential irradiation techniques for whole breast RT （radiotherapy） CT （computed tomography） based 2D （two dimensional） technique with wedge filters and 3D CRT （three dimensional conformal radiotherapy） with segmented fields. These two modalities are commonly used in external beam radiotherapy of breast cancer in Clinical Center Nis, Clinic of Oncology, Serbia. Therapy plans that employed two techniques were generated for eighteen patients. Dosimetric outcomes of each technique were investigated. The maximum dose of breast CTV was significantly reduced from 55.83 Gy for 2D to 54.1 Gy for 3D CRT. Also, the maximum dose of lung tissue decreased from 51.81 Gy for 2D to 49.61 Gy for 3D. The dose conformity and uniformity were much better with 3D CRT segmented field technique.展开更多
Research on the solar magnetic field and its effects on solar dynamo mechanisms and space weather events has benefited from the continual improvements in instrument resolution and measurement frequency.The augmentatio...Research on the solar magnetic field and its effects on solar dynamo mechanisms and space weather events has benefited from the continual improvements in instrument resolution and measurement frequency.The augmentation and assimilation of historical observational data timelines also play a significant role in understanding the patterns of solar magnetic field variation.Within the realm of astronomical data processing,super-resolution(SR)reconstruction refers to the process of using a substantial corpus of training data to learn the nonlinear mapping between low-resolution(LR)and high-resolution(HR)images,thereby achieving higherresolution astronomical images.This paper is an application study in high-dimensional nonlinear regression.Deep learning models were employed to perform SR modeling on SOHO/MDI magnetograms and SDO/HMI magnetograms,thus reliably achieving resolution enhancement of full-disk SOHO/MDI magnetograms and enhancing the image resolution to obtain more detailed information.For this study,a data set comprising 9717pairs of data from 2010 April to 2011 February was used as the training set,1332 pairs from 2011 March were used as the validation set and 1034 pairs from 2011 April were used as the test set.After data preprocessing,we randomly cropped 128×128 sub-images as the LR cases from the full-disk MDI magnetograms,and the corresponding 512×512 sub-images as HR ones from the HMI full-disk magnetograms for model training.The tests conducted have shown that the study successfully produced reliable 4×SR reconstruction of full-disk MDI magnetograms.The MESR model's results(0.911)were highly correlated with the target HMI magnetographs as indicated by the correlation coefficient values.Furthermore,the method achieved the best PSNR,SSIM,MAE and RMSE values,indicating that the MESR model can effectively reconstruct magnetograms.展开更多
目的探讨抗核抗体(ANA)与低分子肝素(LMWH)治疗不明原因复发性流产(URSA)孕妇子宫胎盘血流指数的关系。方法2020年1月至2022年12月期间,共纳入80例URSA孕妇,其中40例接受LMWH治疗,另外40例未接受LMWH治疗,2组ANA阴性(-)和ANA阳性(+)各2...目的探讨抗核抗体(ANA)与低分子肝素(LMWH)治疗不明原因复发性流产(URSA)孕妇子宫胎盘血流指数的关系。方法2020年1月至2022年12月期间,共纳入80例URSA孕妇,其中40例接受LMWH治疗,另外40例未接受LMWH治疗,2组ANA阴性(-)和ANA阳性(+)各20例。借助虚拟器官计算机辅助分析技术进行2D多普勒测量子宫动脉搏动指数(PI)和3D超声测定血管化指数(VI)、血流指数(FI)和血管化血流指数(VFI),并对所有女性进行血清ANA测定。结果未接受LMWH治疗和接受LMWH治疗的ANA(-)URSA孕妇分娩孕周、新生儿结局比较,差异具有统计学意义(P<0.05)。无论ANA状态如何,未接受LMWH治疗和接受LMWH治疗的URSA孕妇间PI、VFI、FI值差异均无统计学意义(P>0.05)。而接受LMWH治疗的ANA(-)URSA孕妇VI值显著高于未接受LMWH治疗的ANA(-)URSA孕妇(20.02±6.06 vs 11.60±3.04,P<0.001)。仅考虑ANA(-)URSA患者,VI用于区分接受和未接受LMWH治疗孕妇的ROC曲线下面积为0.889(标准误=0.053,P<0.001,95%置信区间=0.785~0.993),VI临界值为16.05,灵敏度为75.0%,特异性为100.0%。结论LMWH可能对于恢复ANA(-)状态下URSA女性VI的生理血流供应具有潜在的有益作用,但是仍需要更进一步的研究来解释彼此之间的关系。展开更多
基金supported by the Natural Science Foundation of Sichuan Province of China,Nos.2022NSFSC1545 (to YG),2022NSFSC1387 (to ZF)the Natural Science Foundation of Chongqing of China,Nos.CSTB2022NSCQ-LZX0038,cstc2021ycjh-bgzxm0035 (both to XT)+3 种基金the National Natural Science Foundation of China,No.82001378 (to XT)the Joint Project of Chongqing Health Commission and Science and Technology Bureau,No.2023QNXM009 (to XT)the Science and Technology Research Program of Chongqing Education Commission of China,No.KJQN202200435 (to XT)the Chongqing Talents:Exceptional Young Talents Project,No.CQYC202005014 (to XT)。
文摘Epilepsy can be defined as a dysfunction of the brain network,and each type of epilepsy involves different brain-network changes that are implicated diffe rently in the control and propagation of interictal or ictal discharges.Gaining more detailed information on brain network alterations can help us to further understand the mechanisms of epilepsy and pave the way for brain network-based precise therapeutic approaches in clinical practice.An increasing number of advanced neuroimaging techniques and electrophysiological techniques such as diffusion tensor imaging-based fiber tra ctography,diffusion kurtosis imaging-based fiber tractography,fiber ball imagingbased tra ctography,electroencephalography,functional magnetic resonance imaging,magnetoencephalography,positron emission tomography,molecular imaging,and functional ultrasound imaging have been extensively used to delineate epileptic networks.In this review,we summarize the relevant neuroimaging and neuroelectrophysiological techniques for assessing structural and functional brain networks in patients with epilepsy,and extensively analyze the imaging mechanisms,advantages,limitations,and clinical application ranges of each technique.A greater focus on emerging advanced technologies,new data analysis software,a combination of multiple techniques,and the construction of personalized virtual epilepsy models can provide a theoretical basis to better understand the brain network mechanisms of epilepsy and make surgical decisions.
文摘With the advent of the information age, people＇ s lives have been changed unknowingly owing to lots of modem technology means. For the environmental artistic design, the traditional mode of environmental artistic design is broken through after the emergence of computer technology and virtual reality technique, which makes the scheme and application of virtual reality technique in environmental artistic design to own more practical value. In this paper, the virtual reality technique and its practical application in environmental artistic design are set forth, and the profound influence on the actual design by the virtual reality technique is studied with expectation of enlightenment for broadening the thought of environmental artistic design.
文摘The virtual technique in Chinese drama makes the aesthetic feeling of the audiences enriched in enjoying the art of stage performance to their heart＇s content when the reality of life is reflected by drama. Also, the position of the animation art has been promoted by the expression and extension of the drama art spirit and expression technique in the creation of film and television animations to be greatly improved. In this paper, the characteristics of the virtual technique in drama are briefly introduced, and also the influence of the virtual technique on the creation offihn and television animations is analyzed.
文摘Twenty years after its introduction, computed tomographic colonography (CTC) has reached its maturity, and it can reasonably be considered the best radiological diagnostic test for imaging colorectal cancer (CRC) and polyps. This examination technique is less invasive than colonoscopy (CS), easy to perform, and standardized. Reduced bowel preparation and colonic distention using carbon dioxide favor patient compliance. Widespread implementation of a new image reconstruction algorithm has minimized radiation exposure, and the use of dedicated software with enhanced views has enabled easier image interpretation. Integration in the routine workflow of a computer-aided detection algorithm reduces perceptual errors, particularly for small polyps. Consolidated evidence from the literature shows that the diagnostic performances for the detection of CRC and large polyps in symptomatic and asymptomatic individuals are similar to CS and are largely superior to barium enema, the latter of which should be strongly discouraged. Favorable data regarding CTC performance open the possibility for many different indications, some of which are already supported by evidence-based data: incomplete, failed, or unfeasible CS; symptomatic, elderly, and frail patients; and investigation of diverticular disease. Other indications are still being debated and, thus, are recommended only if CS is unfeasible: the use of CTC in CRC screening and in surveillance after surgery for CRC or polypectomy. In order for CTC to be used appropriately, contraindications such as acute abdominal conditions (diverticulitis or the acute phase of inflammatory bowel diseases) and surveillance in patients with a long-standing history of ulcerative colitis or Crohn’s disease and in those with hereditary colonic syndromes should not be overlooked. This will maximize the benefits of the technique and minimize potential sources of frustration or disappointment for both referring clinicians and patients.
文摘We compared DVHs （dose volume histograms） of two tangential irradiation techniques for whole breast RT （radiotherapy） CT （computed tomography） based 2D （two dimensional） technique with wedge filters and 3D CRT （three dimensional conformal radiotherapy） with segmented fields. These two modalities are commonly used in external beam radiotherapy of breast cancer in Clinical Center Nis, Clinic of Oncology, Serbia. Therapy plans that employed two techniques were generated for eighteen patients. Dosimetric outcomes of each technique were investigated. The maximum dose of breast CTV was significantly reduced from 55.83 Gy for 2D to 54.1 Gy for 3D CRT. Also, the maximum dose of lung tissue decreased from 51.81 Gy for 2D to 49.61 Gy for 3D. The dose conformity and uniformity were much better with 3D CRT segmented field technique.
基金funded by the National Natural Science Foundation of China(NSFC,Grant No.12003068)Yunnan Key Laboratory of Solar Physics and Space Science under the number 202205AG070009。
文摘Research on the solar magnetic field and its effects on solar dynamo mechanisms and space weather events has benefited from the continual improvements in instrument resolution and measurement frequency.The augmentation and assimilation of historical observational data timelines also play a significant role in understanding the patterns of solar magnetic field variation.Within the realm of astronomical data processing,super-resolution(SR)reconstruction refers to the process of using a substantial corpus of training data to learn the nonlinear mapping between low-resolution(LR)and high-resolution(HR)images,thereby achieving higherresolution astronomical images.This paper is an application study in high-dimensional nonlinear regression.Deep learning models were employed to perform SR modeling on SOHO/MDI magnetograms and SDO/HMI magnetograms,thus reliably achieving resolution enhancement of full-disk SOHO/MDI magnetograms and enhancing the image resolution to obtain more detailed information.For this study,a data set comprising 9717pairs of data from 2010 April to 2011 February was used as the training set,1332 pairs from 2011 March were used as the validation set and 1034 pairs from 2011 April were used as the test set.After data preprocessing,we randomly cropped 128×128 sub-images as the LR cases from the full-disk MDI magnetograms,and the corresponding 512×512 sub-images as HR ones from the HMI full-disk magnetograms for model training.The tests conducted have shown that the study successfully produced reliable 4×SR reconstruction of full-disk MDI magnetograms.The MESR model's results(0.911)were highly correlated with the target HMI magnetographs as indicated by the correlation coefficient values.Furthermore,the method achieved the best PSNR,SSIM,MAE and RMSE values,indicating that the MESR model can effectively reconstruct magnetograms.
文摘目的探讨抗核抗体(ANA)与低分子肝素(LMWH)治疗不明原因复发性流产(URSA)孕妇子宫胎盘血流指数的关系。方法2020年1月至2022年12月期间,共纳入80例URSA孕妇,其中40例接受LMWH治疗,另外40例未接受LMWH治疗,2组ANA阴性(-)和ANA阳性(+)各20例。借助虚拟器官计算机辅助分析技术进行2D多普勒测量子宫动脉搏动指数(PI)和3D超声测定血管化指数(VI)、血流指数(FI)和血管化血流指数(VFI),并对所有女性进行血清ANA测定。结果未接受LMWH治疗和接受LMWH治疗的ANA(-)URSA孕妇分娩孕周、新生儿结局比较,差异具有统计学意义(P<0.05)。无论ANA状态如何,未接受LMWH治疗和接受LMWH治疗的URSA孕妇间PI、VFI、FI值差异均无统计学意义(P>0.05)。而接受LMWH治疗的ANA(-)URSA孕妇VI值显著高于未接受LMWH治疗的ANA(-)URSA孕妇(20.02±6.06 vs 11.60±3.04,P<0.001)。仅考虑ANA(-)URSA患者,VI用于区分接受和未接受LMWH治疗孕妇的ROC曲线下面积为0.889(标准误=0.053,P<0.001,95%置信区间=0.785~0.993),VI临界值为16.05,灵敏度为75.0%,特异性为100.0%。结论LMWH可能对于恢复ANA(-)状态下URSA女性VI的生理血流供应具有潜在的有益作用,但是仍需要更进一步的研究来解释彼此之间的关系。
