AIM: To evaluate contrast visual acuity(CVA) after implantation of an aspheric apodized diffractive intraocular lens(IOL) or a spherical apodized diffractive IOL in cataract surgery. ·METHODS: This prospective ra...AIM: To evaluate contrast visual acuity(CVA) after implantation of an aspheric apodized diffractive intraocular lens(IOL) or a spherical apodized diffractive IOL in cataract surgery. ·METHODS: This prospective randomized controlled study with a 12-month follow-up compared the results of cataract surgery with implantation of an aspheric AcrySof ReSTOR SN6AD3 IOL(30 eyes) and a spherical AcrySof ReSTOR SN60D3 IOL(30 eyes). CVA with best distance correction was measured at 4 contrast levels(100%,25%,10% and 5%) under 3 levels of chart luminance [250,85 and 25 candelas per square meter(cd/m2)] using a multi-functional visual acuity tester(MFVA-100). ·RESULTS: At 12 months after surgery,there were no statistically significant differences in 100% CVA and 25% CVA under 250cd/m2(P100% =0.875 and P25% =0.057) and 85cd/m2(P100% =0.198 and P25% =0.193) between the aspheric group and the spherical group. However,the 10% CVA and 5% CVA were significant better in aspheric group than spherical group under 250cd/m2(P10% =0.042 and P5% = 0.007) and 85cd/m2(P10% =0.002 and P5%=0.039). Under the luminance level of 25cd/m 2,no significant differences was found in the 100% CVA between the 2 group(P100% = 0.245),while aspheric group had better visual acuity in the remaining 3 contracts(P25% =0.023,P10% =0.026 and P5% = 0.002,respectively). ·CONCULSION: The aspheric AcrySof ReSTOR SN6AD3 IOL provided patients with better low-contrast visual acuity than the spherical AcrySof ReSTOR SN60D3 IOL.展开更多
AIM:To assess the effects of upper lid blepharoplasty on visual quality.METHODS:Seventy-three eyelids of 39 patients were subjected to upper lid blepharoplasty.Pre- and postoperative contrast sensitivity,visual acui...AIM:To assess the effects of upper lid blepharoplasty on visual quality.METHODS:Seventy-three eyelids of 39 patients were subjected to upper lid blepharoplasty.Pre- and postoperative contrast sensitivity,visual acuity,vertical palpebral aperture and the degree of lash ptosis were measured.RESULTS:The mean log contrast sensitivities under photopic(P =0.017) and scotopic conditions(P =0.009)were improved after surgery,and these differences were significant.The degree of lash ptosis was also decreased after blepharoplasty(P〈0.001).CONCLUSION:In our study,a significant increase in contrast sensitivity was found after surgery.These results suggest that upper lid blepharoplasty can be helpful for improving visual quality.展开更多
AIM:To compare visual performance of wavefrontguided laser in situ keratomileusis(LASIK) with iris-registration(Wg-LASIK group) and conventional LASIK(LASIK group) one year after surgery and analyze the correlation be...AIM:To compare visual performance of wavefrontguided laser in situ keratomileusis(LASIK) with iris-registration(Wg-LASIK group) and conventional LASIK(LASIK group) one year after surgery and analyze the correlation between wavefront aberrations and visual performance.·METHODS:Eight hundred and fifty-two myopic eyes of 430 patients were enrolled in this prospective study and divided into two groups:Wg-LASIK group(436eyes) and LASIK group(416 eyes).A Wavescan Wavefront aberrometer was used to analyze Zernike coefficients and the root-mean-square(RMS) of higher order aberrations,and Optec 6500 visual function instrument was used to measure contrast sensitivity(CS)before and 3,6,12 months after surgery.·RESULTS:The mean spherical equivalent(SE) in WgLASIK group was significantly better than those in LASIK group one year after surgery(P =0.024).Wg-LASIK eyes showed better CS values than LASIK eyes at all spatial frequencies with and without glare after surgery(P all【0.01).Moreover,the increase of higher RMS(RMSh),coma,RMS3,RMS4,RMS5 in Wg-LASIK group were significantly lower than those in LASIK group 1 year after surgery(P all 【0.05).The increase of coma,spherical aberration(SA),RMS3 and RMS4 in Wg-LASIK and coma and RMS3 in LASIK group were negatively correlated with reduction of contrast sensitivity 1 year after surgery.·CONCLUSION:A significant better visual performance is got in Wg-LASIK group compared with LASIK group 1year after surgery,and the Wg-LASIK is particularly suitable for eyes with high-magnitude RMSh.展开更多
To investigate the effects of rigid-gas-permeable contact lens(RGP-CL)wear on Zernike astigmatism and visual performance in myopic eyes.Methods:A wavefront sensor was used to evaluate Zernike astigmatism for 21 eyes w...To investigate the effects of rigid-gas-permeable contact lens(RGP-CL)wear on Zernike astigmatism and visual performance in myopic eyes.Methods:A wavefront sensor was used to evaluate Zernike astigmatism for 21 eyes with minimum astigmatism and 18 eyes with moderate astigmatism under three different modes of refractive correction:the RGP-CL,spectacle lens correcting spherical equivalent(SL)and spectacle lens fully correcting spherical error and astigmatism(fSL).Contrast visual acuity was assessed with a VA tester at four contrast levels and two luminance backgrounds.Results:Compared to the SL wear,RGP-CL wear changed the main axis astigmatism(Z_(2)^(2))from0:09-0:34 to 0.34-0.22 for the minimum astigmatism group,while the contrast VA was improved about 0.05 LogMAR(F=8:06,p<0:01).For the group with moderate astigmatism,significant reduction in Z_(2)^(2)was found for both fSL wear(t=4:78,p<0:001)and RGP-CL wear(t=6:29,p<0:0001).The changes in astigmatism were significantly correlated between the fSL and RGP-CL wears(r=0:897,p<0:0001 for Z_(2)^(-2);and r=0:643,p=0:004 for Z_(2)^(2)).Contrast VA was significantly improved for both fSL and RGP-CL wears and the improvements were significantly correlated between each other for all four contrast levels and two backgrounds.Conclusion:RGP-CL wear induces astigmatism for the eyes with minor astigmatism probably due to a correction of corneal astigmatism and thus a manifesting of the lens astigmatism.For the astigmatic eyes,RGP-CL wear has similar effect on correcting astigmatism as the spectacle lens wear with spherical-cylinder correction and also produces similar visual improvement.展开更多
This study examined the effect on gait of de-grading visual input by simulation on a course with obstacles. Thirty healthy, young adult males walked on a 6 m path with three obstacles (height: 5, 10, 20 cm, width: 10 ...This study examined the effect on gait of de-grading visual input by simulation on a course with obstacles. Thirty healthy, young adult males walked on a 6 m path with three obstacles (height: 5, 10, 20 cm, width: 10 cm) set at inter-vals of 150 cm with and without degraded visual input from light-scattering goggles. Gait was examined with respect to time, length, angle and walk speed parameters. Gait changed signifi-cantly in the degraded visual input condition. The distances between the obstacles and foot before the obstacles were significantly larger in 10 and 20 cm obstacles under the degraded visual input condition, but distances after passing the obstacle had no significant difference among obstacle height. We therefore conclude that a decrease of visual function alters the perception of an obstacle’s height, particularly the 5 cm height obstacle.展开更多
We developed a psychophysical paradigm for the clinical assessment of the contrast sensitivity (CS) mediated by the ON- and OFF-systems of the Magnocellular and Parvocellular pathways. We designed a stimulus consideri...We developed a psychophysical paradigm for the clinical assessment of the contrast sensitivity (CS) mediated by the ON- and OFF-systems of the Magnocellular and Parvocellular pathways. We designed a stimulus considering two dimensions: two spatial frequencies (0.5 and 4.5 cpd) and two temporal rates of flicker (33 ms and 1500 ms). To evidence the ON- and OFF responses, the CS was measured for two polarities of light with luminance changes of 0.6 dB steps above and below the medium luminance grey background. We tested 38 healthy volunteers. The results shows that Magnocellular contrast sensitivity was higher than Parvocellular for the 33 ms flickering stimulus and the Parvocellular contrast sensitivity was higher than Magnocellular for 1500 ms stimuli. The reliability of the test was checked and confirmed. We concluded that the test performs a rapid measurement of the CS mediated by the ON and OFF systems of Magnocellular and Parvocellular pathways. It is useful in clinical protocols due to its high sensitivity and good reliability.展开更多
Most of Image Quality Assessment (IQA) metrics consist of two processes. In the first process, quality map of image is measured locally. In the second process, the last quality score is converted from the quality map ...Most of Image Quality Assessment (IQA) metrics consist of two processes. In the first process, quality map of image is measured locally. In the second process, the last quality score is converted from the quality map by using the pooling strategy. The first process had been made effective and significant progresses, while the second process was always done in simple ways. In the second process of the pooling strategy, the optimal perceptual pooling weights should be determined and computed according to Human Visual System (HVS). Thus, a reliable spatial pooling mathematical model based on HVS is an important issue worthy of study. In this paper, a new Visual Perceptual Pooling Strategy (VPPS) for IQA is presented based on contrast sensitivity and luminance sensitivity of HVS. Experimental results with the LIVE database show that the visual perceptual weights, obtained by the proposed pooling strategy, can effectively and significantly improve the performances of the IQA metrics with Mean Structural SIMilarity (MSSIM) or Phase Quantization Code (PQC). It is confirmed that the proposed VPPS demonstrates promising results for improving the performances of existing IQA metrics.展开更多
AIMTo analyze the relationship between two visual functions and refractive, topographic, pachymetric and aberrometric indicators in eyes with keratoconus.METHODSCorrected distance visual acuity (CDVA), and letter cont...AIMTo analyze the relationship between two visual functions and refractive, topographic, pachymetric and aberrometric indicators in eyes with keratoconus.METHODSCorrected distance visual acuity (CDVA), and letter contrast sensitivity (CS) were correlated with refraction, corneal topography, pachymetry, and total corneal wavefront data prospectively in 71 eyes with keratoconus. The topographic indices assessed were simulated keratometry for the flattest and steepest meridians (SimK1 and SimK2), posterior steeper K (Ks), elevation value in best-fit sphere (BFS) maps, squared eccentricity (Є<sup>2</sup>), aspheric asymmetric index (AAI), pachymetry, thickness progression index (TPI), the amount of pachymetric decentralization (APD), and GalileiTM-keratoconus indices.RESULTSThe mean CDVA (expressed as logMAR) were 0.25±0.21. The mean CS was 1.25±0.46. The spherical refraction correlated well with CDVA (r=-0.526, P<0.001). From topographic indices, SRI correlated with CS (r=-0.695), and IAI with CS (r=-0.672) (P<0.001 for all). Root mean square (RMS) was 4.3±1.81 µm, spherical aberration (SA) was -0.4±0.67 µm, vertical and horizontal coma were -2.1±1.47 and -0.4±0.72 µm. All wavefront data (except horizontal coma), AAI, Є<sup>2</sup> and maximum BFS correlated significantly with the visual function (P≤0.001 for all).CONCLUSIONIn this study, CS is more affected than CDVA as a visual function. The quantity and quality of vision is significantly correlated with well-known and new topographic indices. There is not a significant correlation between visual function and pachymetric parameters. The significantly correlated indices can be used in staging keratoconus and to follow the outcome of a treatment.展开更多
Visual secret sharing (VSS) is one of the cryptographic techniques of Image secret sharing scheme (ISSS) that performs encoding of secret message image (text or picture) into noise like black and white images, which a...Visual secret sharing (VSS) is one of the cryptographic techniques of Image secret sharing scheme (ISSS) that performs encoding of secret message image (text or picture) into noise like black and white images, which are called as shares. Shares are stacked together and secret message image is decoded using human visual system. One of the major drawbacks of this scheme is its poor contrast of the recovered image, which improves if computational device is available while decoding. In this paper, we propose to improve poor contrast of classical VSS schemes for text or alphanumeric secret messages and low entropy images. Initially, stacked image is binarized using dynamic threshold value. A mathematical morphological operation is applied on the stacked image to enhance contrast of the reconstructed image. Moreover, a method is proposed that allows the size of the structuring element to change according to the contrast and the size of a stacked image. We perform experiments for different types of VSS schemes, different share patterns, different share types (rectangle and circle), and low entropy images. Experimental results demonstrate the efficacy of the proposed scheme.展开更多
目的:研究单眼屈光参差性弱视患者对一阶光栅锐度和二阶纹理敏感度的感知能力。方法:收集2018-01/2022-12于我院确诊的单眼屈光参差性弱视儿童715例715眼作为弱视组,另选取矫正视力正常儿童745例745眼作为正常对照组。分别检测最佳矫正...目的:研究单眼屈光参差性弱视患者对一阶光栅锐度和二阶纹理敏感度的感知能力。方法:收集2018-01/2022-12于我院确诊的单眼屈光参差性弱视儿童715例715眼作为弱视组,另选取矫正视力正常儿童745例745眼作为正常对照组。分别检测最佳矫正视力(BCVA)、一阶光栅锐度和(或)二阶纹理敏感度,并分析不同程度弱视患者对一阶光栅锐度和二阶纹理敏感度的感知能力。结果:弱视组与正常对照组一阶光栅锐度(11.58±6.10 vs 20.27±3.47,P<0.001)、二阶纹理敏感度(0.33±0.16 vs 0.12±0.04,P<0.001)均有明显差异,且轻中度弱视患者与重度弱视患者一阶光栅锐度(12.10±6.23 vs 8.13±3.70,P<0.001)和二阶纹理敏感度(0.32±0.16 vs 0.37±0.17,P<0.05)均有明显差异。结论:单眼屈光参差性弱视患者大脑皮层一阶视觉通路和二阶视觉通路均存在不同程度的损伤,重度弱视患者较轻中度弱视患者损伤更为严重。展开更多
文摘AIM: To evaluate contrast visual acuity(CVA) after implantation of an aspheric apodized diffractive intraocular lens(IOL) or a spherical apodized diffractive IOL in cataract surgery. ·METHODS: This prospective randomized controlled study with a 12-month follow-up compared the results of cataract surgery with implantation of an aspheric AcrySof ReSTOR SN6AD3 IOL(30 eyes) and a spherical AcrySof ReSTOR SN60D3 IOL(30 eyes). CVA with best distance correction was measured at 4 contrast levels(100%,25%,10% and 5%) under 3 levels of chart luminance [250,85 and 25 candelas per square meter(cd/m2)] using a multi-functional visual acuity tester(MFVA-100). ·RESULTS: At 12 months after surgery,there were no statistically significant differences in 100% CVA and 25% CVA under 250cd/m2(P100% =0.875 and P25% =0.057) and 85cd/m2(P100% =0.198 and P25% =0.193) between the aspheric group and the spherical group. However,the 10% CVA and 5% CVA were significant better in aspheric group than spherical group under 250cd/m2(P10% =0.042 and P5% = 0.007) and 85cd/m2(P10% =0.002 and P5%=0.039). Under the luminance level of 25cd/m 2,no significant differences was found in the 100% CVA between the 2 group(P100% = 0.245),while aspheric group had better visual acuity in the remaining 3 contracts(P25% =0.023,P10% =0.026 and P5% = 0.002,respectively). ·CONCULSION: The aspheric AcrySof ReSTOR SN6AD3 IOL provided patients with better low-contrast visual acuity than the spherical AcrySof ReSTOR SN60D3 IOL.
文摘AIM:To assess the effects of upper lid blepharoplasty on visual quality.METHODS:Seventy-three eyelids of 39 patients were subjected to upper lid blepharoplasty.Pre- and postoperative contrast sensitivity,visual acuity,vertical palpebral aperture and the degree of lash ptosis were measured.RESULTS:The mean log contrast sensitivities under photopic(P =0.017) and scotopic conditions(P =0.009)were improved after surgery,and these differences were significant.The degree of lash ptosis was also decreased after blepharoplasty(P〈0.001).CONCLUSION:In our study,a significant increase in contrast sensitivity was found after surgery.These results suggest that upper lid blepharoplasty can be helpful for improving visual quality.
文摘AIM:To compare visual performance of wavefrontguided laser in situ keratomileusis(LASIK) with iris-registration(Wg-LASIK group) and conventional LASIK(LASIK group) one year after surgery and analyze the correlation between wavefront aberrations and visual performance.·METHODS:Eight hundred and fifty-two myopic eyes of 430 patients were enrolled in this prospective study and divided into two groups:Wg-LASIK group(436eyes) and LASIK group(416 eyes).A Wavescan Wavefront aberrometer was used to analyze Zernike coefficients and the root-mean-square(RMS) of higher order aberrations,and Optec 6500 visual function instrument was used to measure contrast sensitivity(CS)before and 3,6,12 months after surgery.·RESULTS:The mean spherical equivalent(SE) in WgLASIK group was significantly better than those in LASIK group one year after surgery(P =0.024).Wg-LASIK eyes showed better CS values than LASIK eyes at all spatial frequencies with and without glare after surgery(P all【0.01).Moreover,the increase of higher RMS(RMSh),coma,RMS3,RMS4,RMS5 in Wg-LASIK group were significantly lower than those in LASIK group 1 year after surgery(P all 【0.05).The increase of coma,spherical aberration(SA),RMS3 and RMS4 in Wg-LASIK and coma and RMS3 in LASIK group were negatively correlated with reduction of contrast sensitivity 1 year after surgery.·CONCLUSION:A significant better visual performance is got in Wg-LASIK group compared with LASIK group 1year after surgery,and the Wg-LASIK is particularly suitable for eyes with high-magnitude RMSh.
基金This study was supported by funding from National Natural Science Foundation of China(Grant No.81170869)Grant for Ophthalmology Innovative Research Team of Zhejiang Province(Grant No.2011R09039-08).The authors declare that they have no competing commercial interests.
文摘To investigate the effects of rigid-gas-permeable contact lens(RGP-CL)wear on Zernike astigmatism and visual performance in myopic eyes.Methods:A wavefront sensor was used to evaluate Zernike astigmatism for 21 eyes with minimum astigmatism and 18 eyes with moderate astigmatism under three different modes of refractive correction:the RGP-CL,spectacle lens correcting spherical equivalent(SL)and spectacle lens fully correcting spherical error and astigmatism(fSL).Contrast visual acuity was assessed with a VA tester at four contrast levels and two luminance backgrounds.Results:Compared to the SL wear,RGP-CL wear changed the main axis astigmatism(Z_(2)^(2))from0:09-0:34 to 0.34-0.22 for the minimum astigmatism group,while the contrast VA was improved about 0.05 LogMAR(F=8:06,p<0:01).For the group with moderate astigmatism,significant reduction in Z_(2)^(2)was found for both fSL wear(t=4:78,p<0:001)and RGP-CL wear(t=6:29,p<0:0001).The changes in astigmatism were significantly correlated between the fSL and RGP-CL wears(r=0:897,p<0:0001 for Z_(2)^(-2);and r=0:643,p=0:004 for Z_(2)^(2)).Contrast VA was significantly improved for both fSL and RGP-CL wears and the improvements were significantly correlated between each other for all four contrast levels and two backgrounds.Conclusion:RGP-CL wear induces astigmatism for the eyes with minor astigmatism probably due to a correction of corneal astigmatism and thus a manifesting of the lens astigmatism.For the astigmatic eyes,RGP-CL wear has similar effect on correcting astigmatism as the spectacle lens wear with spherical-cylinder correction and also produces similar visual improvement.
文摘This study examined the effect on gait of de-grading visual input by simulation on a course with obstacles. Thirty healthy, young adult males walked on a 6 m path with three obstacles (height: 5, 10, 20 cm, width: 10 cm) set at inter-vals of 150 cm with and without degraded visual input from light-scattering goggles. Gait was examined with respect to time, length, angle and walk speed parameters. Gait changed signifi-cantly in the degraded visual input condition. The distances between the obstacles and foot before the obstacles were significantly larger in 10 and 20 cm obstacles under the degraded visual input condition, but distances after passing the obstacle had no significant difference among obstacle height. We therefore conclude that a decrease of visual function alters the perception of an obstacle’s height, particularly the 5 cm height obstacle.
文摘We developed a psychophysical paradigm for the clinical assessment of the contrast sensitivity (CS) mediated by the ON- and OFF-systems of the Magnocellular and Parvocellular pathways. We designed a stimulus considering two dimensions: two spatial frequencies (0.5 and 4.5 cpd) and two temporal rates of flicker (33 ms and 1500 ms). To evidence the ON- and OFF responses, the CS was measured for two polarities of light with luminance changes of 0.6 dB steps above and below the medium luminance grey background. We tested 38 healthy volunteers. The results shows that Magnocellular contrast sensitivity was higher than Parvocellular for the 33 ms flickering stimulus and the Parvocellular contrast sensitivity was higher than Magnocellular for 1500 ms stimuli. The reliability of the test was checked and confirmed. We concluded that the test performs a rapid measurement of the CS mediated by the ON and OFF systems of Magnocellular and Parvocellular pathways. It is useful in clinical protocols due to its high sensitivity and good reliability.
基金Supported by the National Natural Science Foundation of China (No. 60832003, 60902096, 61171163, 61071120)the Scientific Research Foundation of Graduate School of Ningbo University
文摘Most of Image Quality Assessment (IQA) metrics consist of two processes. In the first process, quality map of image is measured locally. In the second process, the last quality score is converted from the quality map by using the pooling strategy. The first process had been made effective and significant progresses, while the second process was always done in simple ways. In the second process of the pooling strategy, the optimal perceptual pooling weights should be determined and computed according to Human Visual System (HVS). Thus, a reliable spatial pooling mathematical model based on HVS is an important issue worthy of study. In this paper, a new Visual Perceptual Pooling Strategy (VPPS) for IQA is presented based on contrast sensitivity and luminance sensitivity of HVS. Experimental results with the LIVE database show that the visual perceptual weights, obtained by the proposed pooling strategy, can effectively and significantly improve the performances of the IQA metrics with Mean Structural SIMilarity (MSSIM) or Phase Quantization Code (PQC). It is confirmed that the proposed VPPS demonstrates promising results for improving the performances of existing IQA metrics.
文摘AIMTo analyze the relationship between two visual functions and refractive, topographic, pachymetric and aberrometric indicators in eyes with keratoconus.METHODSCorrected distance visual acuity (CDVA), and letter contrast sensitivity (CS) were correlated with refraction, corneal topography, pachymetry, and total corneal wavefront data prospectively in 71 eyes with keratoconus. The topographic indices assessed were simulated keratometry for the flattest and steepest meridians (SimK1 and SimK2), posterior steeper K (Ks), elevation value in best-fit sphere (BFS) maps, squared eccentricity (Є<sup>2</sup>), aspheric asymmetric index (AAI), pachymetry, thickness progression index (TPI), the amount of pachymetric decentralization (APD), and GalileiTM-keratoconus indices.RESULTSThe mean CDVA (expressed as logMAR) were 0.25±0.21. The mean CS was 1.25±0.46. The spherical refraction correlated well with CDVA (r=-0.526, P<0.001). From topographic indices, SRI correlated with CS (r=-0.695), and IAI with CS (r=-0.672) (P<0.001 for all). Root mean square (RMS) was 4.3±1.81 µm, spherical aberration (SA) was -0.4±0.67 µm, vertical and horizontal coma were -2.1±1.47 and -0.4±0.72 µm. All wavefront data (except horizontal coma), AAI, Є<sup>2</sup> and maximum BFS correlated significantly with the visual function (P≤0.001 for all).CONCLUSIONIn this study, CS is more affected than CDVA as a visual function. The quantity and quality of vision is significantly correlated with well-known and new topographic indices. There is not a significant correlation between visual function and pachymetric parameters. The significantly correlated indices can be used in staging keratoconus and to follow the outcome of a treatment.
文摘Visual secret sharing (VSS) is one of the cryptographic techniques of Image secret sharing scheme (ISSS) that performs encoding of secret message image (text or picture) into noise like black and white images, which are called as shares. Shares are stacked together and secret message image is decoded using human visual system. One of the major drawbacks of this scheme is its poor contrast of the recovered image, which improves if computational device is available while decoding. In this paper, we propose to improve poor contrast of classical VSS schemes for text or alphanumeric secret messages and low entropy images. Initially, stacked image is binarized using dynamic threshold value. A mathematical morphological operation is applied on the stacked image to enhance contrast of the reconstructed image. Moreover, a method is proposed that allows the size of the structuring element to change according to the contrast and the size of a stacked image. We perform experiments for different types of VSS schemes, different share patterns, different share types (rectangle and circle), and low entropy images. Experimental results demonstrate the efficacy of the proposed scheme.
文摘目的:研究单眼屈光参差性弱视患者对一阶光栅锐度和二阶纹理敏感度的感知能力。方法:收集2018-01/2022-12于我院确诊的单眼屈光参差性弱视儿童715例715眼作为弱视组,另选取矫正视力正常儿童745例745眼作为正常对照组。分别检测最佳矫正视力(BCVA)、一阶光栅锐度和(或)二阶纹理敏感度,并分析不同程度弱视患者对一阶光栅锐度和二阶纹理敏感度的感知能力。结果:弱视组与正常对照组一阶光栅锐度(11.58±6.10 vs 20.27±3.47,P<0.001)、二阶纹理敏感度(0.33±0.16 vs 0.12±0.04,P<0.001)均有明显差异,且轻中度弱视患者与重度弱视患者一阶光栅锐度(12.10±6.23 vs 8.13±3.70,P<0.001)和二阶纹理敏感度(0.32±0.16 vs 0.37±0.17,P<0.05)均有明显差异。结论:单眼屈光参差性弱视患者大脑皮层一阶视觉通路和二阶视觉通路均存在不同程度的损伤,重度弱视患者较轻中度弱视患者损伤更为严重。