Background: The associations between the severity of interstitial lung disease and the stage and histologic type of concurrent lung cancer remain unknown. Purpose: To evaluate whether the severity of interstitial lung...Background: The associations between the severity of interstitial lung disease and the stage and histologic type of concurrent lung cancer remain unknown. Purpose: To evaluate whether the severity of interstitial lung abnormality (ILA), as indicated by quantitative computed tomographic (CT) indexes and CT visual score, was correlated with the stage and histological type of concurrent lung cancer. Materials and Methods: Twenty-eight patients with surgically diagnosed lung cancer and ILA on CT were enrolled in this retrospective study. The subjects were allocated to one of three groups by histological type: adenocarcinoma group (13 subjects);squamous cell carcinoma group (10 subjects);and the other histological diagnosis group (5 subjects). Two independent observers evaluated the CT findings to determine the CT visual score, and the kurtosis and skewness of CT-based density histograms were determined. The relationships between severity of ILA and the pathological stage and histological type of concurrent lung cancer were evaluated. Results: There were no significant differences in the CT visual scores and quantitative indexes among the three groups. CT visual score was significantly negatively correlated with pathological stage (r = −0.43, P = 0.025). Conclusion: Patients can have only mild ILA on visual scoring but advanced lung cancer. Therefore, the frequency of follow-up examination should not be based on the severity of ILA on CT.展开更多
Objectives: “Patient-reported outcome measures” has been used extensively, and it has shown the diseases’ impact on patient quality of life and has enabled the clinician to evaluate the clinical care efficacy. In t...Objectives: “Patient-reported outcome measures” has been used extensively, and it has shown the diseases’ impact on patient quality of life and has enabled the clinician to evaluate the clinical care efficacy. In the literature, there are more than 34 shoulder function assessment scoring instruments;the Modified Constant Murley Score (M-CMS) is one of the most popular scores. Although, the M-CMS had been translated and culturally adapted to Danish, Brazilian and Turkish versions, there is no Arabic version found in the literature. We aim to translate and culturally adapt M-CMS into the Arabic language. Method: The M-CMS was translated using previously published guidelines. The translation and cultural adaptation were done in five stages, initial translation by two bilingual translators then a synthesis of the translations after that, back translation by two native English speakers. Then an expert committee meeting approved the pre-final Arabic version. Finally, a pilot test was conducted on 41 patients to ensure its validity. Results: The M-CMS was successfully translated from the original English version to the Arabic version;no difficulties in the translation process were faced. Conclusion: A validated Arabic version of the M-CMS was produced and ready to be used for functional assessment of different shoulder pathologies in Arabic-speaking countries. Future study is needed for translation and cultural adaptation of the English standardized test protocol to assure the reproducibility of the Arabic version of the M-CMS.展开更多
目的:研究爱丁堡观察性步态评估量表(Edinburgh visual gait score,EVGS)的信度,并与三维步态分析进行比较,评价其有效性;同时分析EVGS各项内部以及与脑性瘫痪(cerebral palsy,CP)儿童粗大运动功能分级系统(gross motor function classi...目的:研究爱丁堡观察性步态评估量表(Edinburgh visual gait score,EVGS)的信度,并与三维步态分析进行比较,评价其有效性;同时分析EVGS各项内部以及与脑性瘫痪(cerebral palsy,CP)儿童粗大运动功能分级系统(gross motor function classification system,GMFCS)的相关性,为EVGS在临床应用提供客观依据。方法:从2019年至2021年所有在同济大学附属养志康复医院三维步态分析实验室进行三维步态分析的727例痉挛型CP儿童中随机抽取20例CP,分别由4名不同经验背景的评估者采用EVGS对20例CP的步行视频进行评估,并在间隔1个月后再次评估同一视频。采用同类相关系数分析(intragroup correlation coefficient,ICC)检验4名评估者的间信度,以及同一评估者的重测信度;采用Spearman等级相关系数检验EVGS总分及各项与三维步态分析数据和GMFCS之间的相关性。结果:评估者间第一次评估ICC值为0.947(P<0.001),第二次评估ICC值为0.952(P<0.001),两次评定结果均显示不同评估者对同一组视频采用EVGS的一致性结果较好。各评估者前后两次重测结果显示ICC系数均≥0.75(P<0.0010),表明间隔1个月,同一评估者前后两次评估结果具有较高一致性。相关性分析结果发现,EVGS与三维步态分析结果为中等相关,在校学生评估的总分与校标相关性最大。EVGS与GMFCS等级具有相关性。EVGS各项内相关性分析结果表明,足、骨盆及躯干控制的评估分项对EVGS评估整体步态的结果具有影响。结论:EVGS量表的评估者间信度以及同一评估者重测信度均具有较高可信性,未有丰富的临床经验背景下的评估者使用EVGS同样可以达到较高信效度。相关性分析结果表明,EVGS评估结果的准确性仍存在不足,EVGS评估结果与CP儿童运动功能障碍水平具有相关性,在设备有限情况下,EVGS可以作为步态分析的替补工具,是目前较为可靠的观察性步态评估量表之一。展开更多
文摘Background: The associations between the severity of interstitial lung disease and the stage and histologic type of concurrent lung cancer remain unknown. Purpose: To evaluate whether the severity of interstitial lung abnormality (ILA), as indicated by quantitative computed tomographic (CT) indexes and CT visual score, was correlated with the stage and histological type of concurrent lung cancer. Materials and Methods: Twenty-eight patients with surgically diagnosed lung cancer and ILA on CT were enrolled in this retrospective study. The subjects were allocated to one of three groups by histological type: adenocarcinoma group (13 subjects);squamous cell carcinoma group (10 subjects);and the other histological diagnosis group (5 subjects). Two independent observers evaluated the CT findings to determine the CT visual score, and the kurtosis and skewness of CT-based density histograms were determined. The relationships between severity of ILA and the pathological stage and histological type of concurrent lung cancer were evaluated. Results: There were no significant differences in the CT visual scores and quantitative indexes among the three groups. CT visual score was significantly negatively correlated with pathological stage (r = −0.43, P = 0.025). Conclusion: Patients can have only mild ILA on visual scoring but advanced lung cancer. Therefore, the frequency of follow-up examination should not be based on the severity of ILA on CT.
文摘Objectives: “Patient-reported outcome measures” has been used extensively, and it has shown the diseases’ impact on patient quality of life and has enabled the clinician to evaluate the clinical care efficacy. In the literature, there are more than 34 shoulder function assessment scoring instruments;the Modified Constant Murley Score (M-CMS) is one of the most popular scores. Although, the M-CMS had been translated and culturally adapted to Danish, Brazilian and Turkish versions, there is no Arabic version found in the literature. We aim to translate and culturally adapt M-CMS into the Arabic language. Method: The M-CMS was translated using previously published guidelines. The translation and cultural adaptation were done in five stages, initial translation by two bilingual translators then a synthesis of the translations after that, back translation by two native English speakers. Then an expert committee meeting approved the pre-final Arabic version. Finally, a pilot test was conducted on 41 patients to ensure its validity. Results: The M-CMS was successfully translated from the original English version to the Arabic version;no difficulties in the translation process were faced. Conclusion: A validated Arabic version of the M-CMS was produced and ready to be used for functional assessment of different shoulder pathologies in Arabic-speaking countries. Future study is needed for translation and cultural adaptation of the English standardized test protocol to assure the reproducibility of the Arabic version of the M-CMS.
