Background: Mobility limitations and cognitive impairments which are common with ageing often coexist, causing a reduction in the levels of physical and mental activity and are prognostic of future adverse health even...Background: Mobility limitations and cognitive impairments which are common with ageing often coexist, causing a reduction in the levels of physical and mental activity and are prognostic of future adverse health events and falls. Consequently, multi-task training paradigms that simultaneously address both mobility and cognition benefit healthy ageing are important to consider in rehabilitation as well as primary prevention. Objectives: An exploratory RCT is being conducted to: a) describe the feasibility and acceptability of the study design and process, procedures, resources and management in two game-based dual-task training programs delivered in the community;b) to explore the lived experiences of the study participants who completed their respective exercise programs. A secondary objective is to obtain preliminary data on the therapeutic effectiveness of the two dual-task training programs. Methods: Thirty healthy older community dwelling participants aged 70 - 85 with previous history of falls will be recruited and randomized to either dual- task treadmill walking (experimental group) or dual-task recumbent bicycle (control group). Data analysis: The qualitative data will be analyzed by two investigators using a content analysis approach. For the quantitative data, outcome measures will be collected pre and post intervention and included measures to assess core balance, spatial-temporal gait variables, visual tracking and cognitive function, as well as, balance and gait analysis under dual-task conditions. Discussion: This research will demonstrate the feasibility of the dual-task training programs in the community, and demonstrate the system’s ability to improve targeted and integrated (dual-task) aspects of balance, mobility, gaze, and cognitive performance. A blended analysis of balance, mobility gaze and cognition will also contribute to a better understanding of the functional consequences of decline in physical and mental skills with age. Trial registration: This pilot clinical trial has been registered at ClinicalTrials.gov Protocol Registration System: NCT01940055.展开更多
光场图像作为一种能够捕获场景每个位置光线信息的图像类型,在电子成像、医学影像和虚拟现实等领域具有广泛的应用前景.光场图像质量评估(Light Field Image Quality Assessment,LFIQA)旨在衡量此类图像的质量,但当前方法面临视觉效果...光场图像作为一种能够捕获场景每个位置光线信息的图像类型,在电子成像、医学影像和虚拟现实等领域具有广泛的应用前景.光场图像质量评估(Light Field Image Quality Assessment,LFIQA)旨在衡量此类图像的质量,但当前方法面临视觉效果与文本模态间异构性的重要挑战.为解决上述问题,本文提出了一种基于文本-视觉的多模态光场图像质量评估模型.具体来说,在视觉模态方面,我们设计了多任务模型,结合边缘自动阈值算法有效丰富了光场图像的关键表示特征.在文本模态方面,基于输入噪声特征与预测噪声特征的对比,准确识别光场图像的噪声类别,并验证了噪声预测对优化视觉表示的重要性.基于上述研究,进一步提出了一种优化的通用噪声文本配置方法,并结合边缘增强策略,显著提升了基线模型在光场图像质量评估中的准确性和泛化能力.此外,通过消融实验,评估了各组件对整体模型性能的贡献,验证了本文方法的有效性和稳健性.实验结果表明,该方法不仅在公开数据集Win5-LID和NBU-LF1.0的实验中表现出色,还在融合数据集中展示出优秀的实验结果,与现有最优算法相比,本文所提方法在两个数据库中的性能分别提升了2%和6%.本文提出的噪声验证策略和配置方法不仅为图像质量评估中的噪声预测任务提供了有价值的参考,也可用于其它噪声预测类型的辅助任务.展开更多
文摘Background: Mobility limitations and cognitive impairments which are common with ageing often coexist, causing a reduction in the levels of physical and mental activity and are prognostic of future adverse health events and falls. Consequently, multi-task training paradigms that simultaneously address both mobility and cognition benefit healthy ageing are important to consider in rehabilitation as well as primary prevention. Objectives: An exploratory RCT is being conducted to: a) describe the feasibility and acceptability of the study design and process, procedures, resources and management in two game-based dual-task training programs delivered in the community;b) to explore the lived experiences of the study participants who completed their respective exercise programs. A secondary objective is to obtain preliminary data on the therapeutic effectiveness of the two dual-task training programs. Methods: Thirty healthy older community dwelling participants aged 70 - 85 with previous history of falls will be recruited and randomized to either dual- task treadmill walking (experimental group) or dual-task recumbent bicycle (control group). Data analysis: The qualitative data will be analyzed by two investigators using a content analysis approach. For the quantitative data, outcome measures will be collected pre and post intervention and included measures to assess core balance, spatial-temporal gait variables, visual tracking and cognitive function, as well as, balance and gait analysis under dual-task conditions. Discussion: This research will demonstrate the feasibility of the dual-task training programs in the community, and demonstrate the system’s ability to improve targeted and integrated (dual-task) aspects of balance, mobility, gaze, and cognitive performance. A blended analysis of balance, mobility gaze and cognition will also contribute to a better understanding of the functional consequences of decline in physical and mental skills with age. Trial registration: This pilot clinical trial has been registered at ClinicalTrials.gov Protocol Registration System: NCT01940055.
文摘光场图像作为一种能够捕获场景每个位置光线信息的图像类型,在电子成像、医学影像和虚拟现实等领域具有广泛的应用前景.光场图像质量评估(Light Field Image Quality Assessment,LFIQA)旨在衡量此类图像的质量,但当前方法面临视觉效果与文本模态间异构性的重要挑战.为解决上述问题,本文提出了一种基于文本-视觉的多模态光场图像质量评估模型.具体来说,在视觉模态方面,我们设计了多任务模型,结合边缘自动阈值算法有效丰富了光场图像的关键表示特征.在文本模态方面,基于输入噪声特征与预测噪声特征的对比,准确识别光场图像的噪声类别,并验证了噪声预测对优化视觉表示的重要性.基于上述研究,进一步提出了一种优化的通用噪声文本配置方法,并结合边缘增强策略,显著提升了基线模型在光场图像质量评估中的准确性和泛化能力.此外,通过消融实验,评估了各组件对整体模型性能的贡献,验证了本文方法的有效性和稳健性.实验结果表明,该方法不仅在公开数据集Win5-LID和NBU-LF1.0的实验中表现出色,还在融合数据集中展示出优秀的实验结果,与现有最优算法相比,本文所提方法在两个数据库中的性能分别提升了2%和6%.本文提出的噪声验证策略和配置方法不仅为图像质量评估中的噪声预测任务提供了有价值的参考,也可用于其它噪声预测类型的辅助任务.