Vitrectomy combined with silicone oil tamponade in the treatment of severely traumatized eyes with the visual acuity of no light perception

AIM: To evaluate the efficacy of surgical treatment of vitrectomy combined with silicone oil tamponade in the treatment of severely traumatized eyes with the visual acuity of no light perception (NLP).METHODS: This was a retrospective uncontrolled interventional case-series of 19 patients of severely traumatized eyes with NLP who underwent vitrectomy surgery at the Affiliated Hospital of Medical College, Qingdao University (Qingdao, China) during a 3-year period. We recorded perioperative factors with the potential to influence functional outcome including duration from the injury to intervention; causes for ocular trauma; open globe or closed globe injury; grade of vitreous hemorrhage; grade of endophthalmitis; grade of retinal detachment; size and location of intraocular foreign body (IOFB); extent and position of retinal defect; grade of proliferative vitreoretinopathy (PVR); type of surgery; perioperative complications and tamponade agent. The follow-up time was from 3 to 18 months, and the mean time was 12 months.RESULTS: After a mean follow-up period of 12 months (3-18 months) 10.53% (2/19) of eyes had visual acuity of between 20/60 and 20/400, 52.63% (10/19) had visual acuity less than 20/400 but more than NLP, and 36.84% (7/19) remained NLP. Visual acuity was improved from NLP to light perception (LP) or better in 63.16% (12/19) of eyes and the rate of complete retinal reattachment was 73.68% (14/19). Good visual acuity all resulted from those patients of blunt trauma with intact eyewall (closed globe injury). The perioperative factors of poor visual acuity prognosis included delayed intervention; open globe injury; endophthalmitis; severe retinal detachment; large IOFB; macular defect; a wide range of retinal defects andsevere PVR.CONCLUSION: The main reasons of NLP after ocular trauma are severe vitreous hemorrhage opacity; refractive media opacity; retinal detachment; retinal and uveal damages and defects, especially defects of the macula; PVR and endophthalmitis. NLP after ocular trauma in some cases does not mean permanent vision loss. Early intervention of vitrectomy combined with silicone oil tamponade and achieving retinal reattachment of the remaining retina, may make the severely traumatized eyes regain the VA of LP or better.

Axial length,vitreoretinal pathology,and anterior chamber depth can predict postoperative refractive outcomes in phacovitrectomy/silicone oil removal

AIM:To evaluate the postoperative refractive prediction error(PE)and determine the factors that af fect the refractive outcomes of combined pars plana vitrectomy(PPV)or silicone oil removal(SOR)with cataract surgery.METHODS:The study is a retrospective,case-series study.Totally 301 eyes of 301 patients undergoing combined PPV/SOR with cataract surgery were enrolled.Eligible individuals were separated into four groups according to their preoperative diagnoses:silicone oil-filled eyes after PPV(group 1),epiretinal membrane(group 2),macular hole(group 3),and primary retinal detachment(RD;group 4).The variables af fecting postoperative refractive outcomes were analyzed,including age,gender,preoperative best-corrected visual acuity(BCVA),axial length(AL),keratometry average,anterior chamber depth(ACD),intraocular tamponade,and vitreoretinal pathology.The outcome measurements include the mean refractive PE and the proportions of eyes with a PE within±0.50 diopter(D)and±1.00 D.RESULTS:For all patients,the mean PE was-0.04±1.17 D,and 50.17%of patients(eyes)had a PE within±0.50 D.There was a significant difference in refractive outcomes among the four groups(P=0.028),with RD(group 4)showing the least favorable refractive outcome.In multivariate regression analysis,only AL,vitreoretinal pathology,and ACD were strongly associated with PE(all P<0.01).Univariate analysis revealed that longer eyes(AL>26 mm)and a deeper ACD were correlated with hyperopic PE,and shorter eyes(AL<26 mm)and a shallower ACD were correlated with myopic PE.CONCLUSION:RD patients have the least favorable refractive outcome.AL,vitreoretinal pathology,and ACD are strongly associated with PE in the combined surgery.These three factors affect refractive outcomes and thus can be used to predict a better postoperative refractive outcome in clinical practice.

Outcomes and predictors of vitrectomy and silicone oil tamponade in retinal detachments complicated by proliferative vitreoretinopathy

AIM:To evaluate outcomes and determine factors influencing the outcomes of vitrectomy with silicone oil(SO)endotamponade for the management of rhegmatogenous retinal detachment(RRD)complicated by advanced proliferative vitreoretinopathy(PVR).METHODS:This is a retrospective,interventional case series of eyes with PVR grade C associated RRD with or without prior surgery that underwent vitreoretinal surgery and SO tamponade.Eyes with a minimum follow-up of 6mo after SO extraction were included.Eyes were classified into three PVR subgroups according to severity and extension of proliferation.The influence of several preoperative,intraoperative and postoperative factors upon the functional and anatomical outcomes was assessed using multivariate logistic regression analysis.RESULTS:A hundred and one eyes of 101 patients that met the inclusion criteria were studied.Seventy-five of 101 eyes(74.3%)had successful retinal reattachment after one operation.Increased aqueous cell and flare at the first week exam had a statistically significant association with redetachment,recurrent membrane proliferation and keratopathy.Visual acuity improvement was significantly associated with faint postoperative aqueous inflammation values,primary vitrectomy and PVR outside of the posterior pole.CONCLUSION:Although encouraging anatomical and functional outcomes are achieved after vitrectomy and SO tamponade in eyes with RRD complicated by PVR,an increase in aqueous flare or cells at the first week follow-up is most likely to result in postoperative late complications.Primary vitrectomy,PVR associated with minimal posterior pole extension and absent to mild postoperative aqueous inflammation are associated with improved post-operative final visual acuity.

Clinical effect of peripheral capsule preservation in eyes with silicone oil tamponade

BACKGROUND At present,silicone oil has been widely used in vitrectomy to deal with complex fundus diseases.Usually,cataract extraction is combined with vitrectomy.However,reducing the complications of silicone oil tamponade and facilitating the secondary implantation of intraocular lens(IOL)are still an urgent problem.AIM To evaluate the clinical effect of vitrectomy combined with peripheral capsule preservation(PCP)in eyes with silicone oil tamponade.METHODS This single-center retrospective analysis included 70 patients(73 eyes)who underwent vitrectomy and silicone oil tamponade combined with cataract surgery(stage I)between January 2015 and July 2019.All patients underwent selective reoperation for silicone oil extraction and IOL implantation(stage II)more than 3 mo after stage I.These patients were divided into three groups according to the different lens capsule preservation methods:28 patients(31 eyes)in a whole capsule preserved(WCP)group,17(17 eyes)in a capsule absent(CA)group,and 25(25 eyes)in a peripheral capsule preserved(PCP)group.Intraocular pressure(IOP),best-corrected visual acuity,surgery time,and other complications were recorded at each time point(1 d,1 wk,and 1 mo after stages I and II).RESULTS The IOP values were 14.9±8.2 mmHg in the WCP group,20.3±13.0 mmHg in the CA group,and 14.2±9.7 mmHg in the PCP group(P<0.05)at 1 mo after stage I operation.Five eyes had IOP higher than 30 mmHg,and one eye in the WCP group appeared to have silicone oil entering the anterior chamber.There was no significant difference in IOP among the three groups at any other time point(P>0.05).With IOL implantation,visual acuity improved significantly compared to stage I.The incidence rate of posterior capsule opacity was higher in the WCP group than in the other groups(P<0.001).In the CA group,IOL deviation due to suture relaxation occurred in one case.There was no significant difference in the surgery time among the three groups in stage I(P=0.618).In stage II,the surgery time of the PCP group and WCP group was significantly shorter than that of the AC group(P=0.031).CONCLUSION Preservation of the peripheral capsule in vitrectomy combined with lens removal is a better option.This method has significant advantages in reducing intraoperative and postoperative complications.

Anatomical and functional outcomes after Densiron 68 heavy silicone oil tamponade for complicated retinal detachment in Chinese eyes

AIM:To evaluate the safety and efficacy of Densiron 68 heavy silicone oil (HSO) tamponade for complicated retinal detachment(RD)in Chinese eyes.METHODS:Twenty-one eyes of 21 patients with complicated RD were included in this retrospective study.All patients underwent pars plana vitrectomy with an internal tamponade using Densiron 68 HSO.Anatomical and functional results and complications were evaluated,including retinal status,visual acuity(VA),intraocular pressure(IOP),intraocular inflammation,lens opacity,and HSO emulsification.RESULTS:Allthepatients were followed up for 3mo to1y(5.8±1.16mo).Retinal reattachment was achieved in 19of 21 patients(90.5%).VA improved in 18 of 21 patients(85.7%),from 1.93 logMAR(±0.48)to 1.52 logMAR(±0.45)(P=0.001).Postoperative complications included early dispersion of HSO in 7 eyes(38.8%),cataract in 10 of 18phakic eyes(55.5%),moderate postoperative inflammation reaction in 10 eyes(47.6%),and elevated IOP in 5 eyes(23.8%),all of which were controlled by medication or by surgery.CONCLUSION:Highanatomical and functional success rates can be achieved with primary vitrectomy for complicated RD by using Densiron 68 HSO;however,it should not be ignored that Densiron 68 HSO can cause some complications in the eye.

Clinical Analysis of Early and Mid-late Elevated Intraocular Pressure after Silicone Oil Injection

Purpose:.To discuss the incidence and clinical features of early and mid-late elevated intraocular pressure after pars plana vitrectomy and silicone oil injection, and to evaluate the clinical management of eyes with secondary glaucoma.Methods:.This was an observational consecutive case series of 691 eyes in 679 patients who were treated with pars plana vitrectomy and silicone injection...The diagnostic criteria of early elevated intraocular pressure after silicone oil injection was ≥21 mmHg two weeks after surgery, while mid-late elevated intraocular pressure was ≥21 mmHg after two weeks.The incidence and clinical management of elevated intraocular pressure were analyzed.Results: In total, 211 of 691 eyes(30.54%) developed elevated intraocular pressure two weeks after pars plana vitrecto my and silicone injection. Of the 211 eyes, 101 eyes(47.87%)had ocular inflammation, 64 eyes(30.33%) showed hyphema,35 eyes(16.59%) had silicone oil in the anterior chamber, 6eyes.(2.84%).had excess silicone oil injected,.and 5 eyes(2.37%).had rubeosis irides..Eighty three of 691 eyes(12.01%).developed elevated intraocular pressure after two weeks..Of these 83 eyes, 25 eyes(30.12%) had rubeosis irides,.16 eyes(19.27%) had issues related to topic steroid therapy,.13 eyes.(15.66%).had a papillary block,.silicone oil in the anterior chamber,10 eyes(12.05%) had a silicone emulsion,.10 eyes(12.05%).had peripheral anterior synchiae,.and 9 eyes(10.84%).had silicone oil in the anterior chamber..All eyes with elevated intraocular pressure were treated with antiglaucoma medications and surgeries.Conclusion:.The reasons for elevated intraocular pressure differed between early and mid-late after pars plana vitrectomy and silicone oil injection. The elevated intraocular pressure can be controlled effectively by immediate diagnosis and proper treatment with medicine and operation.

Timely vitrectomy without intraocular lens removal for acute endophthalmitis after cataract surgery

AIM:To investigate the clinical features,causative organisms and effects of timely vitrectomy and silicone oil tamponade without intraocular lens(IOL)removal in the treatment of acute-onset endophthalmitis after cataract surgery(APCE).METHODS:We retrospectively analyzed the clinical features and microbiological factors in 10 eyes of 10 patients with APCE at Tianjin Medical University General Hospital from January 2010 to December 2018.Data on the clinical features,causative organisms,visual acuity,intraocular pressure(IOP)and complications were collected.The mean follow-up period was 25.5 mo.RESULTS:The mean age of the patients was 71.4 y.The mean time between cataract surgery and the onset of endophthalmitis was 2.0 d.Preoperative visual acuity ranged from no light perception to hand motion.After vitrectomy,the visual acuity increased in nine eyes(90%),and was unchanged in one eye(10%).A significant difference was observed between the mean preoperative(36.3±7.1 mm Hg)and postoperative IOP(14.9±4.3 mm Hg,P<0.05).Staphylococcus epidermidis was isolated in 5 eyes,S.aureus in 2 eyes,and Enterococcus in 1 eye.Postoperative complications mainly included fibrin exudates in the anterior chamber at the early stages in all eyes and temporary IOP elevation in one eye.No retinal detachment or ocular atrophy was observed during the follow-up period.CONCLUSION:Under systemic antibiotic treatment and timely diagnosis,vitrectomy and silicone oil tamponade without IOL removal is a safe and effective method for APCE.

Preoperative laser reduces silicone oil use in primary diabetic vitrectomy

AIM: To identify the predictive factors and laser photocoagulation associated with the use of silicone oil as endotamponade during primary diabetic vitrectomy. METHODS: The medical and surgical records of 690 patients(798 eyes) who underwent primary diabetic vitrectomy at a tertiary eye hospital in China from January 2018 to December 2018 were reviewed in this retrospective cohort study. The patients’ baseline characteristics and preoperative treatments were recorded. The binary Logistic regression model was used to evaluate the risk factors for the use of silicone oil as endotamponade agent during primary vitrectomy for proliferative diabetic retinopathy(PDR)-related complications.RESULTS: Among 690 patients with mean age of 52.1±10.5 y(range: 18-85 y), 299/690(43.3%) were female. The 31.6% of the eyes received preoperative laser treatment, and 72.4% of the eyes received preoperative anti-VEGF adjuvant therapy. Non-clearing vitreous haemorrhage(VH) alone or combined with retinal detachment was the main surgical indication(89.5%) for primary vitrectomy. Silicone oil was used as endotamponade in 313(39.2%) eyes. Lack of preoperative laser treatment [odds ratio(OR) 0.66, 95% confidence interval(CI): 0.48-0.92;P=0.015] and older age(OR 0.96, 95%CI: 0.95-0.98;P<0.001) were predictors of silicone oil tamponade during primary vitrectomy for PDR. CONCLUSION: The lack of preoperative laser treatment is a significant predictor of silicone oil tamponade during primary vitrectomy for PDR. However, the severity of PDR relevant to silicone oil use should be further evaluated.

Densiron 68 heavy silicone oil in the management of inferior retinal detachment recurrence: analysis on functional and anatomical outcomes and complications

AIM: To assess the efficacy and safety of a heavy silicone oil(Densiron 68) in the management of inferior retinal detachment recurrence.METHODS: A retrospective non-comparative consecutive case series study. Forty-nine cases of complex inferior retinal detachment were treated using Densiron 68 heavy silicone oil(HSO) as the endotamponade. Our main purpose was anatomic reattachment following Densiron 68 removal. Functional outcomes, rate of recurrences, the presence of inflammatory complications and intraocular pressure alterations were evaluated. RESULTS: Forty-nine patients affected by complex retinal re-detachment were recruited. The mean follow-up was 7.6(±1.5) mo. The mean best corrected visual acuity after Densiron 68 removal was 0.95 log MAR, standard error(SE: 0.068). Retinal reattachment was 61.2% after first surgery and 81.6% after second surgery. Nineteen cases(38.8%) had recurrences when intraocular heavy silicon oil was in situ, 26.3%(5 cases) of which involved the inferior retina. CONCLUSION: Densiron 68 efficiently fills the inferior retinal periphery and might lower the risk of inferior proliferative vitreoretinopathy development, in particular after a standard silicon oil tamponade that reduces the proliferative process in the upper quadrants of the retina.

A pilot study of the precision of digital intraocular pressure measurement during vitrectomy

AIM:To evaluate the precision of digital intraocular pressure(IOP)measurement in silicone oil(SO)filled eyes during vitrectomy.METHODS:This is a retrospective,single-blind study.Patients who were diagnosed with retinal detachment and scheduled for vitrectomy with SO injection were consecutively enrolled.During the vitrectomy,IOP was digitally measured and then by a rebound tonometer(Icare PRO).The rebound tonometer readings were masked to the surgeons.The digitally measured IOP and that of rebound tonometer were compared,and the inter-methods agreement was assessed.The absolute deviation in IOP values between these two methods(△IOP)was also calculated,and correlations between△IOP and refractive status,lens status and levels of surgeons’experience were analyzed.RESULTS:A total of 131 patients(131 eyes)were recruited,with a mean age of 51.0±16.1 y.There was no significant difference in IOPs between digital measurement and the rebound tonometer(15.6±4.3 vs 15.7±5.1 mm Hg;t=0.406,P=0.686).Intraclass correlation coefficients(ICC)analysis indicated a strong correlation between these two measurements(ICC=0.830,P<0.001).The mean△IOP was 2.0±1.9 mm Hg(range:0-12.8 mm Hg),with 98 eyes(74.8%)had the△IOP within 3 mm Hg.△IOP was found to be negatively correlated with levels of surgeons’experience(r=-0.183;P=0.037),but not with the refractive status or lens status of the patients(both P>0.05).CONCLUSION:For experienced surgeons,the digital IOP measurement may be an acceptable technique for IOP measurement in SO filled eyes during vitrectomy.However,its use by inexperienced surgeons should be taken with caution.

高度近视黄斑裂孔性视网膜脱离行玻璃体切割术后C_(3)F_(8)与硅油填充的疗效比较

目的:比较高度近视黄斑裂孔性视网膜脱离(MHRD)行玻璃体切割联合内界膜剥离后玻璃体腔内分别行硅油或C_(3)F_(8)填充治疗的疗效观察。方法:回顾性临床研究。2019-01/2022-08就诊于我院的45例45眼高度近视MHRD患者,根据手术方式分为硅油组(23例)及C_(3)F_(8)组(22例),两组患者均常规三切口玻璃体切割手术,内界膜剥离后行内界膜填塞、自体血覆盖,硅油填充组行硅油填充,C_(3)F_(8)组行15%C_(3)F_(8)气体填充。两组患者分别观察最佳矫正视力(BCVA)、多焦视网膜电图(mfERG)、裂孔的闭合及视网膜复位情况,统计两组患者术后并发症情况。结果:C_(3)F_(8)组、硅油组患者裂孔闭合率为77%、83%(P>0.05),视网膜复位率分别为95%、96%(P>0.05)。C_(3)F_(8)组、硅油组术后视力分别为0.99±0.34、1.22±0.37,C_(3)F_(8)组视力优于硅油组(t=-2.156,P=0.037),两组均较术前显著提高。术后12 mo,两组患者mfERG一阶函数1环(C_(3)F_(8)组114.27±26.37 nV/deg2,硅油组98.08±24.36 nV/deg2)及2环(C_(3)F_(8)组80.45±14.94 nV/deg2,硅油组67.73±15.33 nV/deg2)P1波反应密度较术前(1环P1波反应密度:C_(3)F_(8)组58.13±13.96 nV/deg2、硅油组55.30±10.48 nV/deg2;2环P1波反应密度:C_(3)F_(8)组51.18±8.19 nV/deg2、硅油组47.43±11.97 nV/deg2)明显增加(均P<0.05),C_(3)F_(8)组较硅油组增加明显(P<0.05)。硅油组与C_(3)F_(8)组患者术后并发症发生情况无差异(P>0.05)。结论:玻璃体切割联合内界膜剥离后玻璃体腔内分别行硅油或C_(3)F_(8)填充均可促进高度近视MHRD患者视网膜复位及黄斑裂孔闭合,而且在视功能恢复C_(3)F_(8)填充优于硅油填充。

超声乳化白内障吸除联合玻璃体切割及硅油填充术对糖尿病患者角膜的影响

目的 探究糖尿病视网膜病变患者行超声乳化白内障吸除(Phaco)联合玻璃体切割(PPV)及硅油填充术对角膜的影响。方法 选34例(34眼)视网膜病变患者为研究对象,根据是否合并糖尿病将患者分为糖尿病组与非糖尿病组,各17例(17眼)。所有患者均行Phaco联合PPV及硅油填充术治疗,记录两组并发症发生情况,术前及术后1周、1个月、3个月及6个月测量角膜内皮细胞密度(ECD)、中央角膜厚度(CCT)、角膜前表面曲率、角膜后表面曲率及角膜屈光度,比较两组间的角膜数据。结果 术后1周糖尿病组患者的ECD低于非糖尿病组,术后1周、1个月糖尿病组患者的CCT均厚于非糖尿病组,差异均有统计学意义(均P<0.05)。术后1周糖尿病组患者的角膜前表面曲率K1(平坦轴)的SIA值和角膜前表面曲率K2(陡峭轴)的SIA值均高于非糖尿病组,差异均有统计学意义(均P<0.05);术后1周、1个月、3个月、6个月两组患者术后角膜后表面曲率K1(平坦轴)的SIA值、角膜后表面曲率K2(陡峭轴)的SIA值比较,差异均无统计学意义(均P>0.05)。术后1周糖尿病组患者角膜屈光度的SIA值高于非糖尿病组患者,差异有统计学意义(P<0.05);术后1个月、3个月、6个月两组角膜屈光度的SIA值比较,差异均无统计学意义(均P>0.05)。两组患者均未发生超过24 h持续性高眼压,药物治疗后眼压维持正常,无感染性眼内炎发生。结论 Phaco联合PPV及硅油填充术对糖尿病患者角膜内皮细胞、CCT、角膜前表面曲率及角膜屈光度早期损伤较非糖尿病组更明显,但硅油填充后3—6个月内两组患者角膜内皮细胞、CCT、角膜前后表面曲率及角膜屈光度差异均无统计学意义。因此,Phaco联合PPV及硅油填充术对糖尿病视网膜病变患者是一种相对安全的手术方式。

玻璃体切除术相关视神经病变

玻璃体切除术发明至今已经有50余年的历史,目前在眼科的应用指征涵盖了大部分玻璃体视网膜疾病。尽管随着设备的革新和技术的进步,玻璃体切除术的手术风险已经降至很低,但仍有一些并发症难以避免,意外或原因不明的视功能下降时有发生。玻璃体切除术后视神经病变的发生率较高,可发生于术后即刻或数周至数月,会引起不可逆的视觉损伤。致病原因大致可分为术中视神经损伤和术后继发损伤。术中视神经损伤包括机械性损伤、染料毒性及眼内压影响,术后继发损伤包括眼内压升高、硅油毒性及氧化应激等微环境改变对视神经的损伤。文章将对玻璃体切除术相关视神经病变的临床表现、常见原因及相关管理做一综述,以期引起眼科医生们对于此类疾病的关注。

综合体位干预对玻璃体切割联合硅油填充患者睡眠质量的影响

目的:探讨综合体位干预对玻璃体切割联合硅油填充患者睡眠质量的影响。方法:选取2023年1月至2023年10月福建省三明市第一医院眼科拟行玻璃体切割联合硅油填充术的患者98例作为研究对象,按照随机数字表法分为对照组和观察组,每组49例。对照组实施围手术期常规护理,观察组在对照组基础上加用综合体位干预,2组均干预至出院。比较2组体位依从性、眼压、舒适状况量表(GCQ)、纽卡斯尔护理满意度量表(NSNS)及匹兹堡睡眠质量指数(PSQI)评分。结果:观察组整体体位依从性更优(P<0.05)。干预后,观察组眼压更低(P<0.05),2组GCQ评分有所提高,且观察组更高(P<0.05),观察组NSNS评分更高(P<0.05)。2组PSQI评分先升高后下降,干预后观察组PSQI评分更低,2组组间比较差异有统计学意义(P<0.05)。结论:综合体位干预可提高玻璃体切割联合硅油填充患者体位依从性,降低眼压升高风险,提高患者舒适度、满意度及睡眠质量。

玻璃体切割术联合眼内硅油填充术后患者特殊体位维持情况影响因素及列线图模型的构建

目的 探讨玻璃体切割术(PPV)联合眼内硅油填充术后患者特殊体位维持情况的影响因素,并建立列线图模型。方法 选择463例复杂性视网膜脱离患者作为研究对象,根据入组时间分为建模组(324例)和验证组(139例)。记录患者的特殊体位维持时间,将维持时间<12 h判定为特殊体位维持差,维持时间≥12 h判定为特殊体位维持良好。收集患者的一般资料,并采用焦虑自评量表(SAS)、视觉模拟量表(VAS)、乐商问卷(OQ-Q)、特殊体位知信行问卷对其进行评估。采用多因素Logistic回归模型分析建模组患者特殊体位维持情况的影响因素。基于影响因素构建列线图模型,并评估模型的性能。结果 文化程度、术前OQ-Q评分、术后SAS评分、体位辅具使用情况、术前特殊体位知信行问卷评分、术后胸闷胸痛VAS评分是PPV联合眼内硅油填充术后患者特殊体位维持情况的影响因素(P<0.05)。基于上述影响因素构建的列线图模型的受试者工作特征曲线下面积为0.827~0.835,评估准确性较好,临床效应良好。结论 文化程度、术前OQ-Q评分、术后SAS评分、体位辅具使用情况、术前特殊体位知信行问卷评分、术后胸闷胸痛VAS评分可影响PPV联合眼内硅油填充术后患者的特殊体位维持情况。基于上述影响因素构建的列线图模型准确性较高,具有良好的评估性能和临床应用价值。

最小量外路手术与玻璃体切割术治疗孔源性视网膜脱离的对比研究

目的:对比最小量外路手术与玻璃体切割伴硅油填充术在治疗孔源性视网膜脱离(Rhegmatogenous retinal detachment,RRD)中的疗效。方法:选择2011年1月至2016年12月于赣南医学院第一附属医院眼科就诊的518例RRD(黄斑裂孔除外)患者为研究对象。其中,258例行最小量外路手术(外路组);260例行玻璃体切割伴硅油填充术(玻璃体切割组)。术后随访6个月,比较两组视网膜复位率、最佳矫正视力以及并发症情况。结果:首次手术视网膜复位成功率在外路组及玻璃体切割组分别为96.90%和93.46%,差异无统计学意义(P>0.05)。外路组术后1、3、6月视力提高4行患者比率分别为37.60%、43.41%、48.84%,提高2~4行的患者比率分别为:41.08%、44.57%、46.51%,提高不足2行患者的比率分别为:21.32%、12.02%、4.65%;玻璃体切割组术后1、3、6月视力提高4行的患者比率分别为15.77%、19.23%、21.54%,提高2~4行的患者比率分别为:31.54%、36.15%、37.31%,提高不足2行或视力下降的患者比率分别为:52.69%、44.62%、41.15%,1、3、6个月外路组手术患者视力改善幅度均较玻璃体切割组大,差异有统计学意义(P<0.05)。外路组和玻璃体切割组术后高眼压的发生率分别为1.94%、26.15%,白内障发生率分别为0%、89.23%,外路组白内障和高眼压发生率均小于玻璃体切割组,差异有统计学意义(P<0.05)。结论:虽然最小量外路手术与玻璃体切割术伴硅油填充术治疗孔源性视网膜脱离的首次手术视网膜复位成功率无明显差异,但最小量外路手术患者术后视力收益较好,并发症更少。

玻璃体切割联合硅油填充术后高眼压的病因评价及处理

目的 分析玻璃体切割联合硅油填充术后高眼压的发生原因,并采取针对性干预措施。方法 随机选取2017年1月—2021年12月于兴化市人民医院实施玻璃体切割联合硅油填充术治疗的患者80例为研究对象,并根据眼压是否升高分为对照组(术后眼压正常,n=40)、观察组(术后高眼压,n=40),分析玻璃体切割联合硅油填充术后高眼压的发生原因,同时采取合理措施处理。结果 单因素分析显示,观察组年龄、性别、临床分期以及术后美开朗滴眼液点眼比例与对照组相比,差异无统计学意义(P>0.05),观察组高度近视、硅油填充过量、合并糖尿病、术中晶状体摘除、术中全视网膜光凝或冷冻、术后体位不当与对照组相比,差异有统计学意义(P<0.05)。多因素分析结果显示,高度近视(OR=1.521)、硅油填充过量(OR=1.264)、合并糖尿病(OR=1.568)、术中晶状体摘除(OR=1.614)、术中全视网膜光凝或冷冻(OR=0.314)、术后体位不当(OR=1.271)是诱发高眼压的独立影响因素(P<0.05)。结论 高度近视、糖尿病、术中及术后操作不当均可导致玻璃体切割联合硅油填充术后发生高眼压,因此在治疗中需加强预防及干预,尽可能在术前合理控制患者血糖水平,且操作过程中医务人员需规范自身行为,减少其他因素对治疗及预后效果影响。

玻璃体切除联合硅油填充术治疗糖尿病视网膜病变的愈后及并发症分析

目的探讨玻璃体切除联合眼内硅油填充术治疗糖尿病视网膜病变的视力改善及并发症分析。方法回顾性分析98眼行玻璃体切除联合眼内硅油填充术治疗的糖尿病视网膜病变患者,观察术后视力恢复情况和术后并发症,分析影响视力预后的因素,探讨术后并发症与并发性疾病等其他因素的关系。结果 98眼患者行玻璃体术后视力提高率为66.33%,术后并发黄斑病变组的视力改善率(55.26%)显著低于无黄斑病变组的视力改善率(73.33%)(P<0.05)。高血压组和糖尿病肾病组的高眼压、新生血管、再出血、黄斑水肿和黄斑前膜的发生率显著高于无高血压组和无糖尿病肾病组(P<0.05)。血糖控制状况良好和较短的糖尿病史可以显著降低高眼压、再出血、黄斑水肿和黄斑前膜的发生率(P<0.05)。高血压组和糖尿病肾病组的高眼压、新生血管、再出血、黄斑水肿和黄斑前膜的发生率显著高于无高血压组和无糖尿病肾病组(P<0.05)。血糖控制状况良好和较短的糖尿病史可以显著降低高眼压、再出血、黄斑水肿和黄斑前膜的发生率(P<0.05)。结论玻璃体切除联合眼内硅油填充术治疗糖尿病视网膜病变可以显著提高患者术后视力,且术后是否并发黄斑病变是影响视力改善的重要因素,术后并发症的发生率与并发性疾病、血糖控制和糖尿病史密切相关。

白内障超声乳化人工晶状体植入联合硅油取出术临床疗效观察

目的探讨玻璃体切割术后硅油充填眼行白内障超声乳化人工晶状体植入联合硅油取出术的临床疗效。方法 2010年8月—2011年6月对35例(36眼)玻璃体切割术后硅油充填眼白内障患者行白内障超声乳化人工晶状体植入联合硅油取出术,观察患者术后1个月最佳矫正视力以及术后并发症发生情况。结果术后1个月,3眼(8.33%)最佳矫正视力<0.01,5眼(13.89%)为0.01～0.04,10眼(27.78%)为0.05～0.09,15眼(41.67%)为0.1～0.25,3眼(8.33%)≥0.3。所有患者均无持续性角膜内皮失代偿、硅油泡残留、人工晶状体移位和玻璃体出血等并发症发生。结论玻璃体切割术后硅油充填眼行白内障超声乳化人工晶状体植入联合硅油取出术安全、有效。

玻璃体切割硅油填塞术后眼压变化分析

目的观察玻璃体切割硅油填塞术后的眼压变化,并探讨其可能原因。方法对45例(45眼)玻璃体切割硅油填塞术后患者的临床资料进行回顾性分析,高眼压标准为术后眼压≥24 mmHg(1 mmHg=0.133 kPa)。结果 22例(48.9%)患者出现高眼压,以术后早期(术后2周内)为多(17/22,77.3%)。所有患者经降眼压药物治疗及调整激素用量或停用激素处理后,眼压均控制在正常范围。高眼压组与非高眼压组性别、年龄、病程、屈光度及硅油填充量比较差异均无统计学意义(P>0.05)。结论高眼压是玻璃体切割硅油填充术后常见的并发症,术后眼内组织水肿、葡萄膜炎反应和频繁使用激素类滴眼液等可能是引起高眼压的主要原因。