To solve the greasiness and irritation risks brought about by organic sun-screening agents in sunscreen emulsions,in this work,a sunscreen O/W/Si multiple emulsion was prepared by two-step emulsification method,in whi...To solve the greasiness and irritation risks brought about by organic sun-screening agents in sunscreen emulsions,in this work,a sunscreen O/W/Si multiple emulsion was prepared by two-step emulsification method,in which the outer oil phase was silicone oil and the inner oil phase was solid lipid nanoparticles coated with organic sun-screening agent.Several influencing factors on the formation and stability of the emulsion were analyzed,including inorganic salts,the volume fraction of outer oil phase(silicone oil),and the dosage of W/O emulsifier.The in vitro sunscreen performance,water resistance and skin permeability of different types of sunscreen emulsions were further studied.The results showed that the sunscreen O/W/Si multiple emulsion containing 22.5%silicone oil,2.5%emulsifier and 0.2%NaCl had the best stability under the experimental conditions.The SPF value and water resistance of sunscreen O/W/Si multiple emulsion were slightly higher than those of sunscreen W/O emulsion,but significantly higher than those of sunscreen O/W emulsion.Compared with sunscreen W/O emulsion,the in vitro transdermal permeability of organic sun-screening agent in sunscreen O/W/Si multiple emulsion was reduced by approximately 60%,indicative of higher safety and good application prospect in sunscreen cosmetics.展开更多
The stabilizing conditions of W/O microemulsion of Tx 6～C 4H 9OH/c C 6H 12 /H 2O system were studied by visual observation and electrical conductance.The result shows that when the weight ratio of Tx 6 and C 4H 9OH i...The stabilizing conditions of W/O microemulsion of Tx 6～C 4H 9OH/c C 6H 12 /H 2O system were studied by visual observation and electrical conductance.The result shows that when the weight ratio of Tx 6 and C 4H 9OH is 4∶1,the W/O microemulsion sytem has stabilizing and extensive regions,and the system is insensitive to the values of pH at room temperature.In accordance with the theoretical value of HLB,the suitable value of HLB for Tx 6 and C 4H 9OH to compose microemulsion is greater than 9,less than or equal to 10.展开更多
为探究超声处理大豆分离蛋白-壳聚糖(soybean protein isolate-chitosan,SPI-CS)复合物对形成O/W型乳液性质的影响,主要研究了复合物表面疏水性、乳化活性、乳化稳定性与油-水界面张力、乳液粒径、乳液稳定性之间的关系。结果表明:未经...为探究超声处理大豆分离蛋白-壳聚糖(soybean protein isolate-chitosan,SPI-CS)复合物对形成O/W型乳液性质的影响,主要研究了复合物表面疏水性、乳化活性、乳化稳定性与油-水界面张力、乳液粒径、乳液稳定性之间的关系。结果表明:未经超声处理的SPI-CS复合物表面疏水性、乳化活性、乳化稳定性和界面吸附性较低,形成的O/W型乳液粒径相对较大,约100?μm,乳液Zeta电位较低,乳滴有发生聚集的倾向。乳液贮存7 d后乳层析指数最高。经超声处理后SPI-CS复合物形成的乳状液性质发生明显变化,随着超声功率的增加,形成的O/W型乳液的稳定性有所增加:超声功率为400 W时SPI-CS复合物形成的乳液最为稳定,乳层析指数最低;当超声功率超过400 W时,乳液的光学显微镜观察显示其粒径有所增大,同时乳液的Zeta电位、乳化活性和乳化稳定性明显下降,界面张力降低缓慢。超声处理暴露了蛋白质分子的内部结构,使部分结构展开、柔性增加,促进了其与壳聚糖之间的静电相互作用,说明超声处理的大豆分离蛋白与壳聚糖形成的复合物影响了O/W型乳液的稳定性及相关性质。展开更多
文摘To solve the greasiness and irritation risks brought about by organic sun-screening agents in sunscreen emulsions,in this work,a sunscreen O/W/Si multiple emulsion was prepared by two-step emulsification method,in which the outer oil phase was silicone oil and the inner oil phase was solid lipid nanoparticles coated with organic sun-screening agent.Several influencing factors on the formation and stability of the emulsion were analyzed,including inorganic salts,the volume fraction of outer oil phase(silicone oil),and the dosage of W/O emulsifier.The in vitro sunscreen performance,water resistance and skin permeability of different types of sunscreen emulsions were further studied.The results showed that the sunscreen O/W/Si multiple emulsion containing 22.5%silicone oil,2.5%emulsifier and 0.2%NaCl had the best stability under the experimental conditions.The SPF value and water resistance of sunscreen O/W/Si multiple emulsion were slightly higher than those of sunscreen W/O emulsion,but significantly higher than those of sunscreen O/W emulsion.Compared with sunscreen W/O emulsion,the in vitro transdermal permeability of organic sun-screening agent in sunscreen O/W/Si multiple emulsion was reduced by approximately 60%,indicative of higher safety and good application prospect in sunscreen cosmetics.
文摘The stabilizing conditions of W/O microemulsion of Tx 6～C 4H 9OH/c C 6H 12 /H 2O system were studied by visual observation and electrical conductance.The result shows that when the weight ratio of Tx 6 and C 4H 9OH is 4∶1,the W/O microemulsion sytem has stabilizing and extensive regions,and the system is insensitive to the values of pH at room temperature.In accordance with the theoretical value of HLB,the suitable value of HLB for Tx 6 and C 4H 9OH to compose microemulsion is greater than 9,less than or equal to 10.
