目的评估以丙泊酚作替代的Wada试验对记忆优势半球的判定价值。方法选择2012年2月—2016年12月于河北省人民医院功能神经外科顺利完成Wada试验,并进行手术治疗的颞叶癫痫患者64例。应用中国修订版韦氏记忆量表测定颞叶癫痫患者手术前后...目的评估以丙泊酚作替代的Wada试验对记忆优势半球的判定价值。方法选择2012年2月—2016年12月于河北省人民医院功能神经外科顺利完成Wada试验,并进行手术治疗的颞叶癫痫患者64例。应用中国修订版韦氏记忆量表测定颞叶癫痫患者手术前后记忆商(MQ),比较患者手术治疗前1周与手术后6个月记忆功能的差异。结果所有患者均配合完成测验,MQ平均(96.06±5.54)分,其中长时记忆平均(29.28±2.92)分,短时记忆平均(57.12±4.25)分,瞬时记忆平均(9.65±1.49)分。颞叶癫痫患者MQ和分测验中短时记忆较正常常模(分别为100和60)低,差异有统计学意义(P<0.05)。确定记忆优势半球患者47例,术后6个月再次进行韦氏记忆测验,术前与术后相比较MQ(95.94±5.83 vs. 95.45±5.78)差异无统计学意义,其中长时记忆(29.04±3.19 vs. 28.45±2.83),短时记忆(57.28±4.26 vs. 57.55±4.10),瞬时记忆(9.62±1.54 vs. 9.45±1.56)比较差异均无统计学意义(P>0.05)。结论应用丙泊酚替代的Wada试验对于颞叶癫痫患者的记忆优势半球具有判定作用,可以作为颞叶癫痫患者术前评估的方法。展开更多
The objective is to study changes in EEG time-domain Kolmogorov entropy and cortical lateralization of brain function areas during complex problem solving mental task in healthy human subjects. EEG data for healthy su...The objective is to study changes in EEG time-domain Kolmogorov entropy and cortical lateralization of brain function areas during complex problem solving mental task in healthy human subjects. EEG data for healthy subjects are acquired during complex problem solving mental task using a net of 6 electrodes. The subject was given a nontrivial multiplication problem to solve and the signals were recorded for 10s during the task. Kolmogorov entropy values during the task were calculated. It was found that Kolmogorov entropy values were obviously greater in P4 channel (right) than ones in P3 channel (left) during complex problem solving task. It indicated that all subjects presented significant left parietal lateralization for the total frequency spectrum. These results suggest that it may be possible to noninvasively lateralize, and even eventually localize, cerebral regions essential for particular mental tasks from scalp EEG data.展开更多
文摘目的评估以丙泊酚作替代的Wada试验对记忆优势半球的判定价值。方法选择2012年2月—2016年12月于河北省人民医院功能神经外科顺利完成Wada试验,并进行手术治疗的颞叶癫痫患者64例。应用中国修订版韦氏记忆量表测定颞叶癫痫患者手术前后记忆商(MQ),比较患者手术治疗前1周与手术后6个月记忆功能的差异。结果所有患者均配合完成测验,MQ平均(96.06±5.54)分,其中长时记忆平均(29.28±2.92)分,短时记忆平均(57.12±4.25)分,瞬时记忆平均(9.65±1.49)分。颞叶癫痫患者MQ和分测验中短时记忆较正常常模(分别为100和60)低,差异有统计学意义(P<0.05)。确定记忆优势半球患者47例,术后6个月再次进行韦氏记忆测验,术前与术后相比较MQ(95.94±5.83 vs. 95.45±5.78)差异无统计学意义,其中长时记忆(29.04±3.19 vs. 28.45±2.83),短时记忆(57.28±4.26 vs. 57.55±4.10),瞬时记忆(9.62±1.54 vs. 9.45±1.56)比较差异均无统计学意义(P>0.05)。结论应用丙泊酚替代的Wada试验对于颞叶癫痫患者的记忆优势半球具有判定作用,可以作为颞叶癫痫患者术前评估的方法。
文摘The objective is to study changes in EEG time-domain Kolmogorov entropy and cortical lateralization of brain function areas during complex problem solving mental task in healthy human subjects. EEG data for healthy subjects are acquired during complex problem solving mental task using a net of 6 electrodes. The subject was given a nontrivial multiplication problem to solve and the signals were recorded for 10s during the task. Kolmogorov entropy values during the task were calculated. It was found that Kolmogorov entropy values were obviously greater in P4 channel (right) than ones in P3 channel (left) during complex problem solving task. It indicated that all subjects presented significant left parietal lateralization for the total frequency spectrum. These results suggest that it may be possible to noninvasively lateralize, and even eventually localize, cerebral regions essential for particular mental tasks from scalp EEG data.