Since October 2008,China's social consumption of electricity had,for the first time,grown negatively compared to the same period of the previous year,and in November the negative growth range further expanded. The...Since October 2008,China's social consumption of electricity had,for the first time,grown negatively compared to the same period of the previous year,and in November the negative growth range further expanded. The major pressure faced by the electricity industry has now turned from the contradiction between coal and electricity to electricity quantity. This is undoubtedly a true and new test to electricity enterprises which get used to high growth but are now suffering great losses. The reform of electricity system has already been in great difficulties and now is getting into a more serious situation. In order to help readers improve their knowledge and understanding of the current tough situation faced by the electricity industry and discuss how to alleviate and get through the difficulty resulted from the economic crisis "encountered once every one hundred years" by joint efforts of all parties concerned,a Seminar on Crisis and Countermeasures for Electricity Industry was held on November 20,2008. Here are some extracts from the speeches of four experts.展开更多
Absurdity originated from French existentialism,and Martin Esslin,in categorizing Waiting for Godot as a theater of the absurd,ignores the positive aspects of Camus’s absurdism and regards that as an existential trag...Absurdity originated from French existentialism,and Martin Esslin,in categorizing Waiting for Godot as a theater of the absurd,ignores the positive aspects of Camus’s absurdism and regards that as an existential tragedy of mankind.However,the author Samuel Beckett himself did not approve of such a definition,believing that Esslin’s definition of theater of the absurd was too judgmental and pessimistic.Through the imagery of boots,ropes,hats and baggage in Waiting for Godot,Beckett reveals the rootlessness,constraint and agony of the minds of people born into absurdity in the early 20th century.The luck of Lucky is Beckett’s use of irony:people who have lost the ability to think for themselves escape the absurdity and dystopia of life and descend to slaves.Gogo and Didi,who are waiting and expecting,and thinking in the midst of absurdity,represent“Godot”,the symbol of hope.Their endurance in waiting,akin to Camus’s Sisyphus,underscores a form of existential defiance that challenges the notion of absolute pessimism in absurdist literature.展开更多
The aim of this of this experimental study to investigate the effect of 3 voluntary waiting periods (VWP) on health of dairy cows. A total of 100 lactations of 100 Holstein Friesian cows with high milk production (ave...The aim of this of this experimental study to investigate the effect of 3 voluntary waiting periods (VWP) on health of dairy cows. A total of 100 lactations of 100 Holstein Friesian cows with high milk production (average 9.442 ± 620 kg) were randomly (based on the ear tags digits of cows) distributed to 1 to 3 experimental groups with VWP of 50 (VWPG50;n = 32), 100 (VWPG100;n = 34) or 150 days (VWPG150;n = 34). Observations relating to diseases of the cows were made by the farm veterinarian and research personnel. Were defined eight disease: puerperal fever, retained fetal membranes, displaced abomasum, metritis, clinical ketosis, clinical mastitis, ovarian cysts, and claw diseases. The experimental days (ED) were from 4 days in milk (DIM) to 100 days after the next calving. The experiment was managed at Dairy Research Farm ?imnic-Craiova January 2018 to December 2022. A clear set of clinical signs were used to define a case at the diseases without the need for laboratory confirmation. Values of Lactational incidence risk (LIR) median postpartum days at diagnosis and pairwise comparison of proportion between VWPs were calculated. LIR for puerperal fiver, retained fetal membranes, displaced abomasum, clinical ketosis, clinical mastitis, ovarian cysts and claw disease were 4;5;2;8;8;and 4% respectively. Numerically, cows with VWP of 100 and150 days had more disease cases compared with VWP of 50 days. The differences between experimental groups of cows regarding proportions of cows with disease cases were not statistically significant. Any of the eight disorders reported in this study was analyzed independently to other health problems. For all enrolled cows (n = 100) VWP was extended until 100 or 150 days postpartum with no effect on the lactational incidence risk for the eight disorders analyzed.展开更多
As an important representative of the Theatre of Absurd, in his masterpiece Waiting for Godot, Beckett deserted the traditional dramatic form and adopted a new one that shows us the fragmentary characters and the absu...As an important representative of the Theatre of Absurd, in his masterpiece Waiting for Godot, Beckett deserted the traditional dramatic form and adopted a new one that shows us the fragmentary characters and the absurdity of the modern society. This paper demonstrates his artful creation of the language form from the following three aspects: The use of repetition, use of silence and pause and short sentences.展开更多
读者阅读本文时,已经为迎接新的世纪、新的千年的到来而举起过酒杯、燃放过鞭炮、敲响过钟声。本文告诉你:世界上还有不少人认为,新的世纪,新的千年应该始于2001年的元旦!因此,你可能要再庆祝一次: According to the Gregorian(阳历)cal...读者阅读本文时,已经为迎接新的世纪、新的千年的到来而举起过酒杯、燃放过鞭炮、敲响过钟声。本文告诉你:世界上还有不少人认为,新的世纪,新的千年应该始于2001年的元旦!因此,你可能要再庆祝一次: According to the Gregorian(阳历)calendar, which begins the Christian era at year 1 A. D., the third millennium does not begin until 2001.(注意句中的not…until) 因此,美国总统克林顿就曾幽默地说道: Maybe I can do it twice, and I'll be the president of two millennial changes. 克林顿的这次讲话敞开了自己的心扉,说了心里话: Clinton has frequently spoken of his desire to be remembered as a president who prepared the United States for the 21st century. 虽然离下台的日子还远,但是,他已有心理准备。 而下面这句话则表白了他的敬业心,句中的3个parallelisms用得很精彩: I am acutely mindful of the fact that I have 14 months left, and that I need to be out there squeezing the most out of every day and that I need to get as much done as I can for the American people. 最后,下句中的副词值得我们记学: I'm dead serious about it.】展开更多
朋友,你想购买电脑吗?本文的观点是:Wait for It!或曰:且慢! 东南亚的金融危机使其货币大幅度贬值。钱不值钱了,去购买电脑,从本质言,当然是一件“伤心”之举。因为:…bought with devalued coin,is significantly more expensive. 然而...朋友,你想购买电脑吗?本文的观点是:Wait for It!或曰:且慢! 东南亚的金融危机使其货币大幅度贬值。钱不值钱了,去购买电脑,从本质言,当然是一件“伤心”之举。因为:…bought with devalued coin,is significantly more expensive. 然而,货币之贬值并非劝君缓购电脑的根本原因所在: But it's not just currency fluctuations that should influence your buying decision.There are also some other reasons—mostly centring on a computer's most costlycomponent:the processor chip. processor chip者,俗称计算机的心脏——“芯片”也。现在已在使用Pentium 2chips,它与Pentium 166 megahertz processor chips的区别如何呢?本文介绍如下: …but with standard Pentium 166 megahertz processor chips from U.S.manufacturer Intel still costing,$380 a throw,and the latest Pentium 2 chips,whichrun at least double the speed of old-style Pentiums,costing three times that. 基于以上情况,the latest Pentium 2 chips是否会因货币的贬值而降价呢?老百姓的这个善良愿望和简单的推理是有违市场经济规律的: Consumer spending is generally more exposed to poor economic conditions,so展开更多
Several therapeutic procedures have been proposed as bridging treatments for patients with hepatocellular carcinoma(HCC)awaiting liver transplantation(LT).The most used treatments include transarterial chemoembolizati...Several therapeutic procedures have been proposed as bridging treatments for patients with hepatocellular carcinoma(HCC)awaiting liver transplantation(LT).The most used treatments include transarterial chemoembolization and radiofrequency ablation.Surgical resection has also been successfully used as a bridging procedure,and LT should be considered a rescue treatment in patients with previous HCC resection who experience tumor recurrence or post-treatment severe decompensation of liver function.The aims of bridging treatments include decreasing the waiting list dropout rate before transplantation,reducing HCC recurrence after transplantation,and improving post-transplant overall survival.To date,no data from prospective randomized studies are available;however,for HCC patients listed for LT within the Milan criteria,prolonging the waiting time over 6-12 mo is a risk factor for tumor spread.Bridging treatments are useful in containing tumor progression and decreasing dropout.Furthermore,the response to pre-LT treatments may represent a surrogate marker of tumor biological aggressiveness and could therefore be evaluated to prioritize HCC candidates for LT.Lastly,although a definitive conclusion can not be reached,the experiences reported to date suggest a positive impact of these treatments on both tumor recurrence and post-transplant patient survival.Advanced HCC may be downstaged to achieve and maintain the current conventional criteria for inclusion in the waiting list for LT.Recent studies have demonstrated that successfully downstaged patients can achieve a 5-year survival rate comparable to that of patients meeting the conventional criteria without requiring downstaging.展开更多
This paper considers a novel polling system with two classes of message which can experience an up-per bounded time before being served. The station serves these two classes with mixed service discipline, one class wi...This paper considers a novel polling system with two classes of message which can experience an up-per bounded time before being served. The station serves these two classes with mixed service discipline, one class with exhaustive service discipline, and the other with gated service discipline. Using iterative method, we have developed an approximation method to obtain the mean waiting time for each message class. The performance of approximation has been compared with the simulation results. The expression for the upper bound of waiting time is given too.展开更多
A field study and analysis about the thermal comfort was carried out in the waiting room at Beijing West Rail Station in Chinese cold region.Passengers' TSV(thermal sense vote)was obtained using statistical method...A field study and analysis about the thermal comfort was carried out in the waiting room at Beijing West Rail Station in Chinese cold region.Passengers' TSV(thermal sense vote)was obtained using statistical method on the basis of more than 1 200 questionnaires.The linear regression between TSV and indoor temperature indicates that thermal neutral temperature is 25.2 ℃.According to the percentage of satisfaction among all passengers under different indoor temperatures,the acceptable temperature range in the waiting room is 24.2~30.2℃.It is also found that passengers' temporary stay should be taken into consideration for the thermal comfort analysis.Passengers' TSV is not a constant value after they enter the waiting room.In fact,ΔTSV increases as passengers are waiting for the train,and the growing rate is dependent on indoor-outdoor temperature difference.The greater the temperature difference,the faster ΔTSV increases.At last,a linear regression between indoor comfortable temperature and outdoor temperature was generated as the adaptive comfort model.展开更多
Background: Numerous studies of tissues’ regeneration have confessed the recovery of damaged liver by hematopoietic stem cells. The cells act not only by cell replacement in the target organ but also by delivering tr...Background: Numerous studies of tissues’ regeneration have confessed the recovery of damaged liver by hematopoietic stem cells. The cells act not only by cell replacement in the target organ but also by delivering trophic factors that support endogenous liver regeneration. A little is known of how organ-derived signals recruit such committed cells into circulation. Objective: We investigated the roles of noninvasive mechanical percutaneous stress of cirrhotic human liver in numbers fluctuation of trophic, liver-specific alpha-fetoprotein-positive fraction of CD133-positive hematopoietic stem cells in lymphocytes of patients waiting for liver transplantation. Methods: To promote in blood the number of the alpha-fetoprotein-positive fraction of CD133-positive hematopoietic stem cells, committed to liver’ tissue, we activated mechanically the cirrhotic liver of patient by transcutaneous micro vibration received from skin-contacted electro-magnetic vibraphones generated mechanical pulses with amplitude 10 μm and smoothly changing frequency from 0.03 kHz to 18 kHz and back forth during one cycle duration 1 minute. The number of the alpha-fetoprotein-positive fraction of CD133-positive hematopoietic stem cells in lymphocytes of potential recipients was controlled by flow cytometry before and during daily sonication of skin area, which corresponds to liver projection on it. The 15 minutes cyclic sonication of the liver area performed daily for three weeks. Results: The sonication increased significantly averaged number of liver-specific alpha-fetoprotein-positive CD133-positive blood lymphocytes in 2 - 3 times compared to a base lane. The second similar sonication, the same zone after three weeks break showed differences with baseline, but it was statistically insignificant. The result was specifically related to the liver as it showed the control sonication of the backbone’s projection on the skin of a separate group of patients with cirrhotic liver from the waiting list. Conclusion: The stem cells committed to the liver recruit from the bone marrow into circulation, when organ mechanically stresses and secretes specific humoral signals to provoke of lymphopoiesis on host liver repair.展开更多
Waiting for Godot is often regarded as Beckett's masterpiece. This paper is to explore the possible themes in the play.Waiting for the unrealizable tomorrow is a most dominant theme of the play. Through a brief an...Waiting for Godot is often regarded as Beckett's masterpiece. This paper is to explore the possible themes in the play.Waiting for the unrealizable tomorrow is a most dominant theme of the play. Through a brief analysis of the plot, the dominant theme can be demonstrated very clearly.展开更多
The main challenge for container ports is the planning required for berthing container ships while docked in port.Growth of containerization is creating problems for ports and container terminals as they reach their c...The main challenge for container ports is the planning required for berthing container ships while docked in port.Growth of containerization is creating problems for ports and container terminals as they reach their capacity limits of various resources which increasingly leads to traffic and port congestion.Good planning and management of container terminal operations reduces waiting time for liner ships.Reducing the waiting time improves the terminal’s productivity and decreases the port difficulties.Two important keys to reducing waiting time with berth allocation are determining suitable access channel depths and increasing the number of berths which in this paper are studied and analyzed as practical solutions.Simulation based analysis is the only way to understand how various resources interact with each other and how they are affected in the berthing time of ships.We used the Enterprise Dynamics software to produce simulation models due to the complexity and nature of the problems.We further present case study for berth allocation simulation of the biggest container terminal in Iran and the optimum access channel depth and the number of berths are obtained from simulation results.The results show a significant reduction in the waiting time for container ships and can be useful for major functions in operations and development of container ship terminals.展开更多
AIM: To simulate a hypothetical increase of 50% in the number of pancreas-kidney (PK) transplantations using less-than-ideal donors by a mathematical model. METHODS: We projected the size of the waiting list by taking...AIM: To simulate a hypothetical increase of 50% in the number of pancreas-kidney (PK) transplantations using less-than-ideal donors by a mathematical model. METHODS: We projected the size of the waiting list by taking into account the incidence of new patients per year, the number of PK transplantations carried out in the year and the number of patients who died on the waiting list or were removed from the list for other reasons. These variables were treated using a model developed elsewhere. RESULTS: We found that the waiting list demand will meet the number of PK transplantation by the year 2022. CONCLUSION: In future years, it is perfectly possible to minimize the waiting list time for pancreas transplantation through expansion of the donor pool using less-than-ideal donors.展开更多
Suppose that C is a finite collection of patterns. Observe a Markov chain until one of the patterns in C occurs as a run. This time is denoted by τ. In this paper, we aim to give an easy way to calculate the mean wai...Suppose that C is a finite collection of patterns. Observe a Markov chain until one of the patterns in C occurs as a run. This time is denoted by τ. In this paper, we aim to give an easy way to calculate the mean waiting time E(τ) and the stopping probabilities P(τ = τA)with A ∈ C, where τA is the waiting time until the pattern A appears as a run.展开更多
Background: Insufficient capacity for cardiac surgery results in extensive waiting time for patients requiring coronary artery bypass grafting (CABG). Previous studies have reported a consequence of an increased ...Background: Insufficient capacity for cardiac surgery results in extensive waiting time for patients requiring coronary artery bypass grafting (CABG). Previous studies have reported a consequence of an increased risk of mortality while waiting for CABG. Identification of risk factors for mortality is important in patients waiting for CABG. Objectives: To assess mortality rates and identify risk factors for mortality of patients waiting for CABG. Methods: This retrospective cohort study was done on patients waiting for elective CABG in dr. Kariadi General Hospital from January 2018 to December 2020. Identification of risk factors associated with mortality was done on patients who were waiting for CABG using logistic regression methods. Results: There were 162 patients fulfilling the criteria, with a mean waiting time for surgery of 9.8 months. While waiting for CABG surgery, 32 (19.7%) patients died of any cause. Independent risk factors for death while waiting for CABG included left ventricular ejection fraction ≤ 45% (OR 4.75;95% CI 1.76 - 12.78;p = 0.002), left main disease (OR 4.12;95% CI 1.50 - 11.27;p = 0.006), serum creatinine ≥ 1.5 mg/dl (OR 3.71;95% CI 1.41 - 9.74;p = 0.008), and a number of coronary artery disease risk factors ≥ 3 (OR 3.34;95% CI 1.24 - 8.99;p = 0.017). Conclusions: Long waiting time for CABG is associated with a high mortality rate which is influenced by left ventricular ejection fraction ≤ 45%, left main disease, serum creatinine ≥ 1.5 mg/dl, and a number of coronary arteries disease risk factors ≥ 3.展开更多
Waiting for Godot is one of the most famous plays written by Samuel Barclay Beckett, and also is the founding work of"Theatre of the Absurd". In the drama, repetitive phenomena shed light on the whole constr...Waiting for Godot is one of the most famous plays written by Samuel Barclay Beckett, and also is the founding work of"Theatre of the Absurd". In the drama, repetitive phenomena shed light on the whole construction considerably. All the characters were helpless and unthinking. Their dialogues were simple, nonsense and repetitive. Two scenes were cyclical. Repetition was used subtly in order to express the theme of the play, showing mental crisis after depravation of WWII.展开更多
Poetics by Aristotle sets the dogmas for literature,while Waiting for Godot,the representative of the Theater of the Ab⁃surd,violates the former’s principles to achieve certain effects.The thesis will analyze the vio...Poetics by Aristotle sets the dogmas for literature,while Waiting for Godot,the representative of the Theater of the Ab⁃surd,violates the former’s principles to achieve certain effects.The thesis will analyze the violation from the angle of Solidity or Authenticity of art and poetry,which are the likelinessandnecessity,and credibility.By digressing from the traditional rules,Wait⁃ing for Godot helps to create absurdity reflecting the inner loss of people after the war and to form a sense of alienation from reality.展开更多
In the Internet of Things(IoT)scenario,many devices will communi-cate in the presence of the cellular network;the chances of availability of spec-trum will be very scary given the presence of large numbers of mobile u...In the Internet of Things(IoT)scenario,many devices will communi-cate in the presence of the cellular network;the chances of availability of spec-trum will be very scary given the presence of large numbers of mobile users and large amounts of applications.Spectrum prediction is very encouraging for high traffic next-generation wireless networks,where devices/machines which are part of the Cognitive Radio Network(CRN)can predict the spectrum state prior to transmission to save their limited energy by avoiding unnecessarily sen-sing radio spectrum.Long short-term memory(LSTM)is employed to simulta-neously predict the Radio Spectrum State(RSS)for two-time slots,thereby allowing the secondary node to use the prediction result to transmit its information to achieve lower waiting time hence,enhanced performance capacity.A frame-work of spectral transmission based on the LSTM prediction is formulated,named as positive prediction and sensing-based spectrum access.The proposed scheme provides an average maximum waiting time gain of 2.88 ms.The proposed scheme provides 0.096 bps more capacity than a conventional energy detector.展开更多
文摘Since October 2008,China's social consumption of electricity had,for the first time,grown negatively compared to the same period of the previous year,and in November the negative growth range further expanded. The major pressure faced by the electricity industry has now turned from the contradiction between coal and electricity to electricity quantity. This is undoubtedly a true and new test to electricity enterprises which get used to high growth but are now suffering great losses. The reform of electricity system has already been in great difficulties and now is getting into a more serious situation. In order to help readers improve their knowledge and understanding of the current tough situation faced by the electricity industry and discuss how to alleviate and get through the difficulty resulted from the economic crisis "encountered once every one hundred years" by joint efforts of all parties concerned,a Seminar on Crisis and Countermeasures for Electricity Industry was held on November 20,2008. Here are some extracts from the speeches of four experts.
文摘Absurdity originated from French existentialism,and Martin Esslin,in categorizing Waiting for Godot as a theater of the absurd,ignores the positive aspects of Camus’s absurdism and regards that as an existential tragedy of mankind.However,the author Samuel Beckett himself did not approve of such a definition,believing that Esslin’s definition of theater of the absurd was too judgmental and pessimistic.Through the imagery of boots,ropes,hats and baggage in Waiting for Godot,Beckett reveals the rootlessness,constraint and agony of the minds of people born into absurdity in the early 20th century.The luck of Lucky is Beckett’s use of irony:people who have lost the ability to think for themselves escape the absurdity and dystopia of life and descend to slaves.Gogo and Didi,who are waiting and expecting,and thinking in the midst of absurdity,represent“Godot”,the symbol of hope.Their endurance in waiting,akin to Camus’s Sisyphus,underscores a form of existential defiance that challenges the notion of absolute pessimism in absurdist literature.
文摘The aim of this of this experimental study to investigate the effect of 3 voluntary waiting periods (VWP) on health of dairy cows. A total of 100 lactations of 100 Holstein Friesian cows with high milk production (average 9.442 ± 620 kg) were randomly (based on the ear tags digits of cows) distributed to 1 to 3 experimental groups with VWP of 50 (VWPG50;n = 32), 100 (VWPG100;n = 34) or 150 days (VWPG150;n = 34). Observations relating to diseases of the cows were made by the farm veterinarian and research personnel. Were defined eight disease: puerperal fever, retained fetal membranes, displaced abomasum, metritis, clinical ketosis, clinical mastitis, ovarian cysts, and claw diseases. The experimental days (ED) were from 4 days in milk (DIM) to 100 days after the next calving. The experiment was managed at Dairy Research Farm ?imnic-Craiova January 2018 to December 2022. A clear set of clinical signs were used to define a case at the diseases without the need for laboratory confirmation. Values of Lactational incidence risk (LIR) median postpartum days at diagnosis and pairwise comparison of proportion between VWPs were calculated. LIR for puerperal fiver, retained fetal membranes, displaced abomasum, clinical ketosis, clinical mastitis, ovarian cysts and claw disease were 4;5;2;8;8;and 4% respectively. Numerically, cows with VWP of 100 and150 days had more disease cases compared with VWP of 50 days. The differences between experimental groups of cows regarding proportions of cows with disease cases were not statistically significant. Any of the eight disorders reported in this study was analyzed independently to other health problems. For all enrolled cows (n = 100) VWP was extended until 100 or 150 days postpartum with no effect on the lactational incidence risk for the eight disorders analyzed.
文摘As an important representative of the Theatre of Absurd, in his masterpiece Waiting for Godot, Beckett deserted the traditional dramatic form and adopted a new one that shows us the fragmentary characters and the absurdity of the modern society. This paper demonstrates his artful creation of the language form from the following three aspects: The use of repetition, use of silence and pause and short sentences.
文摘读者阅读本文时,已经为迎接新的世纪、新的千年的到来而举起过酒杯、燃放过鞭炮、敲响过钟声。本文告诉你:世界上还有不少人认为,新的世纪,新的千年应该始于2001年的元旦!因此,你可能要再庆祝一次: According to the Gregorian(阳历)calendar, which begins the Christian era at year 1 A. D., the third millennium does not begin until 2001.(注意句中的not…until) 因此,美国总统克林顿就曾幽默地说道: Maybe I can do it twice, and I'll be the president of two millennial changes. 克林顿的这次讲话敞开了自己的心扉,说了心里话: Clinton has frequently spoken of his desire to be remembered as a president who prepared the United States for the 21st century. 虽然离下台的日子还远,但是,他已有心理准备。 而下面这句话则表白了他的敬业心,句中的3个parallelisms用得很精彩: I am acutely mindful of the fact that I have 14 months left, and that I need to be out there squeezing the most out of every day and that I need to get as much done as I can for the American people. 最后,下句中的副词值得我们记学: I'm dead serious about it.】
文摘朋友,你想购买电脑吗?本文的观点是:Wait for It!或曰:且慢! 东南亚的金融危机使其货币大幅度贬值。钱不值钱了,去购买电脑,从本质言,当然是一件“伤心”之举。因为:…bought with devalued coin,is significantly more expensive. 然而,货币之贬值并非劝君缓购电脑的根本原因所在: But it's not just currency fluctuations that should influence your buying decision.There are also some other reasons—mostly centring on a computer's most costlycomponent:the processor chip. processor chip者,俗称计算机的心脏——“芯片”也。现在已在使用Pentium 2chips,它与Pentium 166 megahertz processor chips的区别如何呢?本文介绍如下: …but with standard Pentium 166 megahertz processor chips from U.S.manufacturer Intel still costing,$380 a throw,and the latest Pentium 2 chips,whichrun at least double the speed of old-style Pentiums,costing three times that. 基于以上情况,the latest Pentium 2 chips是否会因货币的贬值而降价呢?老百姓的这个善良愿望和简单的推理是有违市场经济规律的: Consumer spending is generally more exposed to poor economic conditions,so
文摘Several therapeutic procedures have been proposed as bridging treatments for patients with hepatocellular carcinoma(HCC)awaiting liver transplantation(LT).The most used treatments include transarterial chemoembolization and radiofrequency ablation.Surgical resection has also been successfully used as a bridging procedure,and LT should be considered a rescue treatment in patients with previous HCC resection who experience tumor recurrence or post-treatment severe decompensation of liver function.The aims of bridging treatments include decreasing the waiting list dropout rate before transplantation,reducing HCC recurrence after transplantation,and improving post-transplant overall survival.To date,no data from prospective randomized studies are available;however,for HCC patients listed for LT within the Milan criteria,prolonging the waiting time over 6-12 mo is a risk factor for tumor spread.Bridging treatments are useful in containing tumor progression and decreasing dropout.Furthermore,the response to pre-LT treatments may represent a surrogate marker of tumor biological aggressiveness and could therefore be evaluated to prioritize HCC candidates for LT.Lastly,although a definitive conclusion can not be reached,the experiences reported to date suggest a positive impact of these treatments on both tumor recurrence and post-transplant patient survival.Advanced HCC may be downstaged to achieve and maintain the current conventional criteria for inclusion in the waiting list for LT.Recent studies have demonstrated that successfully downstaged patients can achieve a 5-year survival rate comparable to that of patients meeting the conventional criteria without requiring downstaging.
基金Supported by the High Technology Research and Development Program of China(2002AA412010-08) and the National Natural Science Foundation of China(60474031).
文摘This paper considers a novel polling system with two classes of message which can experience an up-per bounded time before being served. The station serves these two classes with mixed service discipline, one class with exhaustive service discipline, and the other with gated service discipline. Using iterative method, we have developed an approximation method to obtain the mean waiting time for each message class. The performance of approximation has been compared with the simulation results. The expression for the upper bound of waiting time is given too.
基金Supported by National Natural Science Foundation of China(20676154)
文摘A field study and analysis about the thermal comfort was carried out in the waiting room at Beijing West Rail Station in Chinese cold region.Passengers' TSV(thermal sense vote)was obtained using statistical method on the basis of more than 1 200 questionnaires.The linear regression between TSV and indoor temperature indicates that thermal neutral temperature is 25.2 ℃.According to the percentage of satisfaction among all passengers under different indoor temperatures,the acceptable temperature range in the waiting room is 24.2~30.2℃.It is also found that passengers' temporary stay should be taken into consideration for the thermal comfort analysis.Passengers' TSV is not a constant value after they enter the waiting room.In fact,ΔTSV increases as passengers are waiting for the train,and the growing rate is dependent on indoor-outdoor temperature difference.The greater the temperature difference,the faster ΔTSV increases.At last,a linear regression between indoor comfortable temperature and outdoor temperature was generated as the adaptive comfort model.
文摘Background: Numerous studies of tissues’ regeneration have confessed the recovery of damaged liver by hematopoietic stem cells. The cells act not only by cell replacement in the target organ but also by delivering trophic factors that support endogenous liver regeneration. A little is known of how organ-derived signals recruit such committed cells into circulation. Objective: We investigated the roles of noninvasive mechanical percutaneous stress of cirrhotic human liver in numbers fluctuation of trophic, liver-specific alpha-fetoprotein-positive fraction of CD133-positive hematopoietic stem cells in lymphocytes of patients waiting for liver transplantation. Methods: To promote in blood the number of the alpha-fetoprotein-positive fraction of CD133-positive hematopoietic stem cells, committed to liver’ tissue, we activated mechanically the cirrhotic liver of patient by transcutaneous micro vibration received from skin-contacted electro-magnetic vibraphones generated mechanical pulses with amplitude 10 μm and smoothly changing frequency from 0.03 kHz to 18 kHz and back forth during one cycle duration 1 minute. The number of the alpha-fetoprotein-positive fraction of CD133-positive hematopoietic stem cells in lymphocytes of potential recipients was controlled by flow cytometry before and during daily sonication of skin area, which corresponds to liver projection on it. The 15 minutes cyclic sonication of the liver area performed daily for three weeks. Results: The sonication increased significantly averaged number of liver-specific alpha-fetoprotein-positive CD133-positive blood lymphocytes in 2 - 3 times compared to a base lane. The second similar sonication, the same zone after three weeks break showed differences with baseline, but it was statistically insignificant. The result was specifically related to the liver as it showed the control sonication of the backbone’s projection on the skin of a separate group of patients with cirrhotic liver from the waiting list. Conclusion: The stem cells committed to the liver recruit from the bone marrow into circulation, when organ mechanically stresses and secretes specific humoral signals to provoke of lymphopoiesis on host liver repair.
文摘Waiting for Godot is often regarded as Beckett's masterpiece. This paper is to explore the possible themes in the play.Waiting for the unrealizable tomorrow is a most dominant theme of the play. Through a brief analysis of the plot, the dominant theme can be demonstrated very clearly.
文摘The main challenge for container ports is the planning required for berthing container ships while docked in port.Growth of containerization is creating problems for ports and container terminals as they reach their capacity limits of various resources which increasingly leads to traffic and port congestion.Good planning and management of container terminal operations reduces waiting time for liner ships.Reducing the waiting time improves the terminal’s productivity and decreases the port difficulties.Two important keys to reducing waiting time with berth allocation are determining suitable access channel depths and increasing the number of berths which in this paper are studied and analyzed as practical solutions.Simulation based analysis is the only way to understand how various resources interact with each other and how they are affected in the berthing time of ships.We used the Enterprise Dynamics software to produce simulation models due to the complexity and nature of the problems.We further present case study for berth allocation simulation of the biggest container terminal in Iran and the optimum access channel depth and the number of berths are obtained from simulation results.The results show a significant reduction in the waiting time for container ships and can be useful for major functions in operations and development of container ship terminals.
基金Supported by LIMs 01 and 37-HCFMUSP, CNPq and FAPESP
文摘AIM: To simulate a hypothetical increase of 50% in the number of pancreas-kidney (PK) transplantations using less-than-ideal donors by a mathematical model. METHODS: We projected the size of the waiting list by taking into account the incidence of new patients per year, the number of PK transplantations carried out in the year and the number of patients who died on the waiting list or were removed from the list for other reasons. These variables were treated using a model developed elsewhere. RESULTS: We found that the waiting list demand will meet the number of PK transplantation by the year 2022. CONCLUSION: In future years, it is perfectly possible to minimize the waiting list time for pancreas transplantation through expansion of the donor pool using less-than-ideal donors.
基金Supported by the National Natural Science Foundation of China(11771286,11371317)the Zhejiang Provincial Natural Science Foundation of China(LQ18A010007)
文摘Suppose that C is a finite collection of patterns. Observe a Markov chain until one of the patterns in C occurs as a run. This time is denoted by τ. In this paper, we aim to give an easy way to calculate the mean waiting time E(τ) and the stopping probabilities P(τ = τA)with A ∈ C, where τA is the waiting time until the pattern A appears as a run.
文摘Background: Insufficient capacity for cardiac surgery results in extensive waiting time for patients requiring coronary artery bypass grafting (CABG). Previous studies have reported a consequence of an increased risk of mortality while waiting for CABG. Identification of risk factors for mortality is important in patients waiting for CABG. Objectives: To assess mortality rates and identify risk factors for mortality of patients waiting for CABG. Methods: This retrospective cohort study was done on patients waiting for elective CABG in dr. Kariadi General Hospital from January 2018 to December 2020. Identification of risk factors associated with mortality was done on patients who were waiting for CABG using logistic regression methods. Results: There were 162 patients fulfilling the criteria, with a mean waiting time for surgery of 9.8 months. While waiting for CABG surgery, 32 (19.7%) patients died of any cause. Independent risk factors for death while waiting for CABG included left ventricular ejection fraction ≤ 45% (OR 4.75;95% CI 1.76 - 12.78;p = 0.002), left main disease (OR 4.12;95% CI 1.50 - 11.27;p = 0.006), serum creatinine ≥ 1.5 mg/dl (OR 3.71;95% CI 1.41 - 9.74;p = 0.008), and a number of coronary artery disease risk factors ≥ 3 (OR 3.34;95% CI 1.24 - 8.99;p = 0.017). Conclusions: Long waiting time for CABG is associated with a high mortality rate which is influenced by left ventricular ejection fraction ≤ 45%, left main disease, serum creatinine ≥ 1.5 mg/dl, and a number of coronary arteries disease risk factors ≥ 3.
文摘Waiting for Godot is one of the most famous plays written by Samuel Barclay Beckett, and also is the founding work of"Theatre of the Absurd". In the drama, repetitive phenomena shed light on the whole construction considerably. All the characters were helpless and unthinking. Their dialogues were simple, nonsense and repetitive. Two scenes were cyclical. Repetition was used subtly in order to express the theme of the play, showing mental crisis after depravation of WWII.
文摘Poetics by Aristotle sets the dogmas for literature,while Waiting for Godot,the representative of the Theater of the Ab⁃surd,violates the former’s principles to achieve certain effects.The thesis will analyze the violation from the angle of Solidity or Authenticity of art and poetry,which are the likelinessandnecessity,and credibility.By digressing from the traditional rules,Wait⁃ing for Godot helps to create absurdity reflecting the inner loss of people after the war and to form a sense of alienation from reality.
文摘In the Internet of Things(IoT)scenario,many devices will communi-cate in the presence of the cellular network;the chances of availability of spec-trum will be very scary given the presence of large numbers of mobile users and large amounts of applications.Spectrum prediction is very encouraging for high traffic next-generation wireless networks,where devices/machines which are part of the Cognitive Radio Network(CRN)can predict the spectrum state prior to transmission to save their limited energy by avoiding unnecessarily sen-sing radio spectrum.Long short-term memory(LSTM)is employed to simulta-neously predict the Radio Spectrum State(RSS)for two-time slots,thereby allowing the secondary node to use the prediction result to transmit its information to achieve lower waiting time hence,enhanced performance capacity.A frame-work of spectral transmission based on the LSTM prediction is formulated,named as positive prediction and sensing-based spectrum access.The proposed scheme provides an average maximum waiting time gain of 2.88 ms.The proposed scheme provides 0.096 bps more capacity than a conventional energy detector.