Objective:To study the efficacy of Professor Zhiqiang Guo's unique sequential herbal therapy in the treatment of premature ovarian insufficiency(POI)of the kidney deficiency and liver constraint pattern.Methods:Ni...Objective:To study the efficacy of Professor Zhiqiang Guo's unique sequential herbal therapy in the treatment of premature ovarian insufficiency(POI)of the kidney deficiency and liver constraint pattern.Methods:Ninety patients with POI who consulted with Professor Guo at Dongzimen Hospital,Beijing University of Chinese Medicine from January 2012 to December 2015 were enrolled.Treatment consisted of sequential therapy using traditional Chinese medicine formulae with the actions of nourishing the liver and kidney.Course of treatment was 3 consecutive menstrual cycles for each participant except for those who became pregnant during treatment.Baseline data including age,course of disease,past medical history,lifestyle,pregnancy outcome,menstrual status(cycle length,menstrual flow duration and volume),as well as gonadal hormone levels before and after treatment were recorded and analyzed.Results:During treatment,18(20.0%)participants became pregnant.Symptoms including scanty menstrual flow,irritability,low libido,insomnia and excessive dreaming at night,nightsweats,hot flashes,and depression were markedly alleviated.Changes in follicle-stimulating hormone(FSH)and luteinizing hormone(LH)levels at early follicular stage were observed(P=.009 and P=.002,respectively),and FSH/LH differed significantly pre-and posttreatment(P=.0.44).Conclusion:Professor Guo's sequential Chinese herbal therapy with the actions of nourishing the liver and kidney to treat POI can enhance ovarian function,promote pregnancy,and improve quality of life.展开更多
目的:研究疏肝滋肾汤治疗膝骨关节炎的临床疗效。方法:80例患者随机分为2组,治疗组40例患者予疏肝滋肾汤,每次300 m L,早晚各1次;对照组40例给予非甾体抗炎药(NSAIDS)美洛昔康口服,1粒/次,1次/日,连服2月,应用WOMAC积分表、膝关节X线评...目的:研究疏肝滋肾汤治疗膝骨关节炎的临床疗效。方法:80例患者随机分为2组,治疗组40例患者予疏肝滋肾汤,每次300 m L,早晚各1次;对照组40例给予非甾体抗炎药(NSAIDS)美洛昔康口服,1粒/次,1次/日,连服2月,应用WOMAC积分表、膝关节X线评价,对比治疗前后、随访6月指标变化。结果:治疗组与对照组总有效率分别为90.0%、77.5%(P<0.05);2组WOMAC评价积分均下降,但治疗组效果明显优于对照组;2组膝关节X线评分均下降,治疗组优于对照组,差异有显著性。结论:疏肝滋肾汤治疗膝骨关节炎疗效确切,能有效缓解膝骨关节炎症状,且副作用少,安全可靠。展开更多
文摘Objective:To study the efficacy of Professor Zhiqiang Guo's unique sequential herbal therapy in the treatment of premature ovarian insufficiency(POI)of the kidney deficiency and liver constraint pattern.Methods:Ninety patients with POI who consulted with Professor Guo at Dongzimen Hospital,Beijing University of Chinese Medicine from January 2012 to December 2015 were enrolled.Treatment consisted of sequential therapy using traditional Chinese medicine formulae with the actions of nourishing the liver and kidney.Course of treatment was 3 consecutive menstrual cycles for each participant except for those who became pregnant during treatment.Baseline data including age,course of disease,past medical history,lifestyle,pregnancy outcome,menstrual status(cycle length,menstrual flow duration and volume),as well as gonadal hormone levels before and after treatment were recorded and analyzed.Results:During treatment,18(20.0%)participants became pregnant.Symptoms including scanty menstrual flow,irritability,low libido,insomnia and excessive dreaming at night,nightsweats,hot flashes,and depression were markedly alleviated.Changes in follicle-stimulating hormone(FSH)and luteinizing hormone(LH)levels at early follicular stage were observed(P=.009 and P=.002,respectively),and FSH/LH differed significantly pre-and posttreatment(P=.0.44).Conclusion:Professor Guo's sequential Chinese herbal therapy with the actions of nourishing the liver and kidney to treat POI can enhance ovarian function,promote pregnancy,and improve quality of life.
文摘目的:研究疏肝滋肾汤治疗膝骨关节炎的临床疗效。方法:80例患者随机分为2组,治疗组40例患者予疏肝滋肾汤,每次300 m L,早晚各1次;对照组40例给予非甾体抗炎药(NSAIDS)美洛昔康口服,1粒/次,1次/日,连服2月,应用WOMAC积分表、膝关节X线评价,对比治疗前后、随访6月指标变化。结果:治疗组与对照组总有效率分别为90.0%、77.5%(P<0.05);2组WOMAC评价积分均下降,但治疗组效果明显优于对照组;2组膝关节X线评分均下降,治疗组优于对照组,差异有显著性。结论:疏肝滋肾汤治疗膝骨关节炎疗效确切,能有效缓解膝骨关节炎症状,且副作用少,安全可靠。
