To facilitate investigation of the effect of imperfect elastic dissipation on the propagation of Rayleigh-type channel waves and use of their quality factors in investigations of the properties of coal seams, a simple...To facilitate investigation of the effect of imperfect elastic dissipation on the propagation of Rayleigh-type channel waves and use of their quality factors in investigations of the properties of coal seams, a simple method for calculating the quality factor QR is proposed in this paper. Introduction of complex velocities into the dispersion function allows calculation of the dispersion function of Rayleigh-type channel waves in coal seams. By the control variable method, we analyzed changes in QR with changes in coal seam thickness and P- and S-wave Q-factors within the coal seam and adjacent rock layers. The numerical results show that the trend of the QR curve is consistent with the group velocity curve. The minimum QR value occurs at the Airy phase frequency; the Airy phase frequency decreases as coal seam thickness increases. The value of QR increases with increasing QS2(quality factor for S wave in coal seam). We can compensate for the absorption of Rayleigh-type channel waves using the computed QR curve. Inversion of the QR curve can also be used to predict the thicknesses and lithologies of coal seams.展开更多
Comprehensive experimental and numerical studies have been undertaken to investigate wave energy dissipation performance and main influencing factors of a lower arc-plate breakwater. The numerical model, which conside...Comprehensive experimental and numerical studies have been undertaken to investigate wave energy dissipation performance and main influencing factors of a lower arc-plate breakwater. The numerical model, which considers nonlinear interactions between waves and the arc-plate breakwater, has been constructed by using the velocity wave- generating method, the volume of fluid (VOF) method and the finite volume method. The results show that the relative width, relative height and relative submergence of the breakwater are three main influencing factors and have significant influence on wave energy dissipation of the lower arc-plate open breakwater. The transmission coefficient is found to decrease with the increasing relative width, and the minimum transmission coefficient is 0.15 when the relative width is 0.45. The reflection coefficient is found to vary slightly with the relative width, and the maximum reflection coefficient is 0.53 when the relative width is 0.45. The transmission and reflection coefficients are shown to increase with the relative wave height for approximately 85% of the experimental tests when the relative width is 0.19 0.45. The transmission coefficients at relative submergences of 0.04, 0.02 and 0 are clearly shown to be greater than those at relative submergences of 0.02 and 0.04, while the reflection coefficient exhibits the opposite relationship. After the wave interacts with the lower arc-plate breakwater, the wave energy is mainly converted into transmission, reflection and dissipation energies. The wave attenuation performance is clearly weakened for waves with greater heights and longer periods.展开更多
Introduction-Objective: COVID-19 is a highly transmissible but often mild viral infection. However, some patients can present severe COVID-19 and subsequently die. The aim of the present study was to assess the risk f...Introduction-Objective: COVID-19 is a highly transmissible but often mild viral infection. However, some patients can present severe COVID-19 and subsequently die. The aim of the present study was to assess the risk factors for COVID-19 related death during the first three waves of the disease at the Epidemic Treatment Center (ETC) of Dakar Principal Hospital (DPH). Method: We conducted a descriptive and analytical perspective survival study from April 4, 2020 to September 25, 2021, including adult patients with COVID-19, hospitalized at the ETC of DPH. Log Rank test and multivariate Cox model were performed to identify risk factors for death. Results: We included 556 COVID-19 patients with mean age of 57 ± 17 years and a male-to-female ratio of 1.26. The number of deaths during one month of follow-up was 41, representing a cumulative risk of 7.4%. The log Rank test showed that being from the third wave (p = 0.0056), advanced age (p = 0.00098), presence of at least one comorbidity (p = 0.034), High blood pressure (p = 0.024), d-dimer level ≥ 1000 IU/L (p Conclusion: Our study showed that elderly and third-wave of COVID-19 patients were more at risk to die. Knowledge of risk factors for COVID-19 related death could improve the prognosis of these patients.展开更多
In this study, a flume experiment was designed to investigate the characteristics of wave-induced pore water pressure in the soil of a silty seabed with different clay contents, soil layer buried depths and wave heigh...In this study, a flume experiment was designed to investigate the characteristics of wave-induced pore water pressure in the soil of a silty seabed with different clay contents, soil layer buried depths and wave heights respectively. The study showed that water waves propagating over silty seabed can induce significant change of pore water pressure, and the amplitude of pore pressure depends on depth of buried soil layer, clay content and wave height, which are considered as the three influencing factors for pore water pressure change. The pressure will attenuate according to exponential law with increase of soil layer buried depth, and the attenuation being more rapid in those soil layers with higher clay content and greater wave height. The pore pressure in silty seabed increases rapidly in the initial stage of wave action, then decreases gradually to a stable value, depending on the depth of buried soil layer, clay content and wave height. The peak value of pore pressure will increase if clay content or depth of buried soil layer decreases, or wave height increases. The analysis indicated that these soils with 5% clay content and waves with higher wave height produce instability in bed easier, and that the wave energy is mostly dissipated near the surface of soils and 5% clay content in soils can prevent pore pressure from dissipating immediately.展开更多
Rationale: In the literature, some risk factors for severity and mortality from COVID-19 have been indicated. However, these factors can change, depending on the characteristics of the population and health services. ...Rationale: In the literature, some risk factors for severity and mortality from COVID-19 have been indicated. However, these factors can change, depending on the characteristics of the population and health services. In this sense, longitudinal studies can be useful for understanding local realities and subsidizing health actions based on these realities. Objective: To analyze the risk factors for severity and death in hospitalized patients with COVID-19. Methods: A retrospective cohort of patients with COVID-19 hospitalized from August 1 to October 16, 2021 (3<sup>rd</sup> wave of the pandemic), notified by the Department of Epidemiological Surveillance of Sao Tome and Principe. We employed measures of strength of associations for the analysis of exposure risk factors. Results: We analyzed 110 hospitalized patients (31.8% severe-critical and 68.2% non-severe). The risk factors for severe forms of COVID-19 were: being aged ≥60 years (RR = 3.3), being male (RR = 2), having comorbidities (RR = 2) and the risk increases to 10-fold for multicomorbidities, with emphasis on obesity, neoplasia, skin-muscle-surgical infection, dementia and to some degree CVD. 62.9% of patients with severe forms of the disease were not vaccinated. Risk factors for death among hospitalized and severe/critical cases, respectively, were having comorbidities (RR = 8 and 2.4) multicomorbidities (RR = 10 and 2.8 for those with 2 comorbidities and RR = 33.3 and 4 for those with 3 or 4 comorbidities), especially diabetes, dementia, neoplasia, cutaneous-muscular infection, and obesity. Although CVD was not associated with risk factors for death, these were the most frequently found among the severely hospitalized and deaths. In addition, important risk factors associated with death were not using corticoids (RR = 3.3, 230-fold risk) and not using anticoagulants-heparin (RR = 1.3, 30% risk) more compared to the severe cases that did use them. Most of the patients who died (63.2%) were not vaccinated. Moreover, having only 1 dose of the vaccine was a risk factor 1.9 times more for death among all hospitalized patients, but in the severe cases, there was no association between the variable vaccination and death. Among those hospitalized with 2 doses, it was a 0.5-fold protective factor among those hospitalized. The Delta variant of Sarscov-2 was the one found among severe cases and deaths investigated by genetic sequencing, with more exuberant clinical features compared to the other 2 previous vaccinations. Conclusion: Being elderly, male and presenting comorbidities, mainly multicomorbidities were the main characteristics associated with severity of COVID-19. On the other hand, comorbidities, and even worse, multicomorbidities, hospitalization for respiratory failure, lowered level of consciousness, no use of corticoid and no use of anticoagulation in critically ill patients, and not having at least 2 doses of vaccine for covid-19, were characteristics associated with death by COVID-19. These results will help inform healthcare providers so that the best interventions can be implemented to improve outcomes for patients with COVID-19. Public health interventions must be carefully tailored and implemented in these susceptible groups to reduce the risk of mortality in patients with COVID-19 and then the risk of major complications. Intensive and regular follow-up is needed to detect early occurrences of clinical conditions.展开更多
The method of complex function and the method of Green's function are used to investigate the problem of SH-wave scattering by radial cracks of any limited length along the radius originating at the boundary of an...The method of complex function and the method of Green's function are used to investigate the problem of SH-wave scattering by radial cracks of any limited length along the radius originating at the boundary of an elliptical hole, and the solution of dynamic stress intensity factor at the crack tip was given. A Green's function was constructed for the problem, which is a basic solution of displacement field for an elastic half space containing a half elliptical gap impacted by anti-plane harmonic linear source force at any point of its horizontal boundary. With division of a crack technique, a series of integral equations can be established on the conditions of continuity and the solution of dynamic stress intensity factor can be obtained. The influence of an elliptical hole on the dynamic stress intensity factor at the crack tip was discussed.展开更多
One-dimensional ring power system is discredited to a number of nodes each containing a generator with internal reactance and load branch of resistance and reactance with a certain power factor. When a disturbance occ...One-dimensional ring power system is discredited to a number of nodes each containing a generator with internal reactance and load branch of resistance and reactance with a certain power factor. When a disturbance occurs at any machine in the power system, simulative analysis is performed to verify how the variation of load power factor affecting the behavior of electromechanical wave propagation by using the MATLAB package, from which different situations are presented and discussed. These results show the type of load has no effect on the behavior of electromechanical wave propagation.展开更多
背景:疼痛是膝骨关节炎的主要症状,严重影响老年患者的生活质量。膝骨关节炎疼痛机制复杂,涉及多组织、多学科,需要可视化分析了解其主要内容与研究热点。目的:运用文献计量学可视化软件分析归纳膝骨关节炎疼痛领域的前沿内容和研究热...背景:疼痛是膝骨关节炎的主要症状,严重影响老年患者的生活质量。膝骨关节炎疼痛机制复杂,涉及多组织、多学科,需要可视化分析了解其主要内容与研究热点。目的:运用文献计量学可视化软件分析归纳膝骨关节炎疼痛领域的前沿内容和研究热点。方法:从Web of Science核心合集(Web of Science Core Collection,WoSCC)中检索2014-2024年膝骨关节炎疼痛领域的相关文献,运用Citespace、VOSviewer和Bibliometrix R-package三个可视化软件进行文献计量与可视化分析。结果与结论:①膝骨关节炎疼痛研究的发文量呈现逐年递增的趋势;②美国、中国、澳大利亚是该领域10年内发文量排名前三的国家;波士顿大学、悉尼大学、弗洛里达大学是发文量前三的科研机构;《OSTEOARTHRITIS AND CARTILAGE》是出版该领域文献最多的期刊,《PAIN》则是该领域被引次数最多的期刊;发文量最多的作者是Fillingim Roger B,该领域的核心作者之间已经建立了一些稳定的团队,但国际性合作尚有欠缺;③膝骨关节炎疼痛患者的日常管理(运动、心理、智能管理)、疼痛的炎症机制、蛋白组学、联合用药、中枢敏化和疼痛调节是膝骨关节炎疼痛研究的重点内容;人工智能辅助、体外冲击波疗法、射频消融术、神经冷冻术、关节腔内注射血液或细胞制剂可能是该领域的研究前沿。展开更多
Since the wind wave model Simulating Waves Nearshore (SWAN) cannot effectively simulate the wave fields near the lateral boundaries, the change characteristics and the distortion ranges of calculated wave factors in...Since the wind wave model Simulating Waves Nearshore (SWAN) cannot effectively simulate the wave fields near the lateral boundaries, the change characteristics and the distortion ranges of calculated wave factors including wave heights, periods, directions, and lengths near the lateral boundaries of calculation domain are carefully studied in the case of different water depths and wind speeds respectively. The calculation results show that the effects of the variety of water depth and wind speed on the modeled different wave factors near the lateral boundaries are different. In the case of a certain wind speed, the greater the water depth is, the greater the distortion range is. In the case of a certain water depth, the distortion ranges defined by the relative errors of wave heights, periods, and lengths are different from those defined by the absolute errors of the corresponding wave factors. Moreover, the distortion ranges defined by the relative errors decrease with the increase of wind speed; whereas the distortion ranges defined by the absolute errors change a little with the variety of wind speed. The distortion range of wave direction decreases with the increase of wind speed. The calculated wave factors near the lateral boundaries with the SWAN model in the actual physical areas, such as Lake Taihu and Lake Dianshan considered in this study, are indeed distorted if the calculation domains are not enlarged on the basis of actual physical areas. Therefore, when SWAN is employed to calculate the wind wave fields near the shorelines of sea or inland lakes, the appropriate approaches must be adopted to reduce the calculation errors.展开更多
Spiral wave could be observed in the excitable media, the neurons are often excitable within appropriateparameters. The appearance and formation of spiral wave in the cardiac tissue is linked to monomorphic ventricula...Spiral wave could be observed in the excitable media, the neurons are often excitable within appropriateparameters. The appearance and formation of spiral wave in the cardiac tissue is linked to monomorphic ventriculartachycardia that can denervate into polymorphic tachycardia and ventricular fibrillation. The neuronal system oftenconsists of a large number of neurons with complex connections. In this paper, we theoretically study the transitionfrom spiral wave to spiral turbulence and homogeneous state (death of spiral wave) in two-dimensional array of theHindmarsh-Rose neuron with completely nearest-neighbor connections. In our numerical studies, a stable rotating spiralwave is developed and selected as the initial state, then the bifurcation parameters are changed to different values toobserve the transition from spiral wave to homogeneous state, breakup of spiral wave and weak change of spiral wave,respectively. A statistical factor of synchronization is defined with the mean field theory to analyze the transition fromspiral wave to other spatial states, and the snapshots of the membrane potentials of all neurons and time series of meanmembrane potentials of all neurons are also plotted to discuss the change of spiral wave. It is found that the sharpchanging points in the curve for factor of synchronization vs. bifurcation parameter indicate sudden transition fromspiral wave to other states. And the results are independent of the number of neurons we used.展开更多
Structure health monitoring based on diagnostic Lamb waves has been found to be one of the most promising techniques recently. This paper has a brief review of the new developments on this method including the basic n...Structure health monitoring based on diagnostic Lamb waves has been found to be one of the most promising techniques recently. This paper has a brief review of the new developments on this method including the basic novel of the method, fundamentals and mathematics of Lamb wave propagation, narrowband and wideband Lamb wave excitation methods, optimization of excitation factors and diagnostic Lamb wave interpretation methods.展开更多
The parameter inversion of internal solitary waves (ISWs) based on optical remote sensing images is a key work. A new approach is proposed and demonstrated for simulating the optical remote sensing images of ISWs with...The parameter inversion of internal solitary waves (ISWs) based on optical remote sensing images is a key work. A new approach is proposed and demonstrated for simulating the optical remote sensing images of ISWs with a smooth surface in the laboratory. An optical remote sensing simulation system used to detect ISWs is constructed by a two-dimensional ISW flume, a LED (light emitting diode) light source and two CCD (charge coupled device) cameras. The optical remote sensing images of the horizontal surface and ISWs propagation images of a vertical side are detected simultaneously, which aims to explore the response of optical remote sensing corresponding to ISWs with the smooth surface. The results show that during the propagation of ISWs, dark pattern images are obtained by CCD 1 camera. The characteristics of the dark patterns vary along with the incident angle of the light source. The characteristic parameters of the optical remote sensing images correspond to the wave factors of vertical profiles. The experiment also shows a positive correlation between the dark pattern width and the half wave width under different amplitudes of ISWs. The system has the advantages of clear phenomenon and high repeatability, which provides the scientific basis for quantitative investigation on imaging mechanism of ISW by optical remote sensing.展开更多
Three methods for studying wave groups and their main parameters for describing wave groupiness are reviewed in this paper. Then they are analyzed and compared combined with field data from both aspects of group heigh...Three methods for studying wave groups and their main parameters for describing wave groupiness are reviewed in this paper. Then they are analyzed and compared combined with field data from both aspects of group height and group length. A method and two parameters that can describe wave groupiness are suggested. The groupiness parameters of sea waves at three field stations are given. The effects of groupiness on both distributions of the wave height and the phase of component waves are investigated. The effects of datum length on the calculated value of grouping parameters are also discussed.展开更多
Retaining walls have been used in many construction projects such as for road and inclined surfaces protection. The damage caused by an earthquake depends on the fundamental frequency, amplitude and the duration of th...Retaining walls have been used in many construction projects such as for road and inclined surfaces protection. The damage caused by an earthquake depends on the fundamental frequency, amplitude and the duration of the seismic motion. These parameters strongly depend on the seismic properties of the layers that are near the surface. In the study of retaining walls, in addition to the infl uence of soil, the infl uence of topography is also important. In the present study, site response analysis is performed by using fi nite element software PLAXIS to obtain the eff ect of various factors such as embedded length of the sheet pile, underground water table, length and angle of the nail, shear wave velocity of soil on site eff ect and dynamic response. Moreover, for better understanding of the eff ect of the above parameters, the stability analysis was performed by using shear reduction method. The results show that an increase in the embedded length of the sheet pile and the length of nailing causes an increase in the amplifi cation factor. Moreover, for shear-wave velocity in the range of 200- 600 m/s, the amplifi cation factor increases with increase of the shear-wave velocity due to the decrease of nonlinear behavior.展开更多
The stability problem is a very important aspect in seismic wave numerical modeling. Based on the theory of seismic waves and constitutive equations of viscoelastic models, the stability problems of finite difference ...The stability problem is a very important aspect in seismic wave numerical modeling. Based on the theory of seismic waves and constitutive equations of viscoelastic models, the stability problems of finite difference scheme for Kelvin- Voigt and Maxwell models with rectangular grids are analyzed. Expressions of stability conditions with arbitrary spatial accuracies for two viscoelastic models are derived. With approximation of quality factor Q≥5, simplified expressions are developed and some numerical models are given to verify the validity of the corresponding theoretical results. Then this paper summarizes the influences of seismic wave velocity, frequency, size of grid and difference coefficients, as well as quality factor on stability condition. Finally the prerequisite conditions of the simplified stability equations are given with error analysis.展开更多
In this paper, according to the relationship of observation spectrum with source spectrum, travel-path attenuation factor and site effect, we use the digital seismic data of moderate-small earthquakes to invert the so...In this paper, according to the relationship of observation spectrum with source spectrum, travel-path attenuation factor and site effect, we use the digital seismic data of moderate-small earthquakes to invert the soft rock site effect and S wave inelastic attenuation under the constraint of site effect, and determine the parameters of path and site. The parameters obtained by this method exclude the topographic effect of seismic stations, and truly reflect the seismic effect of free soft rock sites and the S wave inelastic attenuation in the studied region. The average soft rock site effect is about 1.5 times in the frequency domain of 2-4 Hz and the S wave quality factor is obtained as Qs=278f0.346, which can be directly applied to the stochastic modeling of ground motions in the studied region.展开更多
A one-layer time-invariant eddy viscosity model is specified to develop a mathematical model for describing the essential features of the turbulent wave boundary layer over a rough bed. The functional form of the eddy...A one-layer time-invariant eddy viscosity model is specified to develop a mathematical model for describing the essential features of the turbulent wave boundary layer over a rough bed. The functional form of the eddy viscosity is evaluated based on computational results from a two-equation turbulence model in which the eddy viscosity varies with time and space. The present eddy viscosity model simplifies much of the mathematical complexity in many existing models. Predictions from the present model have been compared with a wide range of experimental data. It is found that the eddy viscosity model adopted in the present study is physically reasonable.展开更多
基金This work is supported by the National Natural Science Foundation of China (No. 41140033).
文摘To facilitate investigation of the effect of imperfect elastic dissipation on the propagation of Rayleigh-type channel waves and use of their quality factors in investigations of the properties of coal seams, a simple method for calculating the quality factor QR is proposed in this paper. Introduction of complex velocities into the dispersion function allows calculation of the dispersion function of Rayleigh-type channel waves in coal seams. By the control variable method, we analyzed changes in QR with changes in coal seam thickness and P- and S-wave Q-factors within the coal seam and adjacent rock layers. The numerical results show that the trend of the QR curve is consistent with the group velocity curve. The minimum QR value occurs at the Airy phase frequency; the Airy phase frequency decreases as coal seam thickness increases. The value of QR increases with increasing QS2(quality factor for S wave in coal seam). We can compensate for the absorption of Rayleigh-type channel waves using the computed QR curve. Inversion of the QR curve can also be used to predict the thicknesses and lithologies of coal seams.
基金supported by the NSFC-Shandong Joint Fund(Grant Nos.U1706220 and U1806227)the National Natural Science Foundation of China(Grant Nos.51709140 and 51879019)the Key Laboratory of Coastal Disasters and Defence of Ministry of Education(Grant No.201703)
文摘Comprehensive experimental and numerical studies have been undertaken to investigate wave energy dissipation performance and main influencing factors of a lower arc-plate breakwater. The numerical model, which considers nonlinear interactions between waves and the arc-plate breakwater, has been constructed by using the velocity wave- generating method, the volume of fluid (VOF) method and the finite volume method. The results show that the relative width, relative height and relative submergence of the breakwater are three main influencing factors and have significant influence on wave energy dissipation of the lower arc-plate open breakwater. The transmission coefficient is found to decrease with the increasing relative width, and the minimum transmission coefficient is 0.15 when the relative width is 0.45. The reflection coefficient is found to vary slightly with the relative width, and the maximum reflection coefficient is 0.53 when the relative width is 0.45. The transmission and reflection coefficients are shown to increase with the relative wave height for approximately 85% of the experimental tests when the relative width is 0.19 0.45. The transmission coefficients at relative submergences of 0.04, 0.02 and 0 are clearly shown to be greater than those at relative submergences of 0.02 and 0.04, while the reflection coefficient exhibits the opposite relationship. After the wave interacts with the lower arc-plate breakwater, the wave energy is mainly converted into transmission, reflection and dissipation energies. The wave attenuation performance is clearly weakened for waves with greater heights and longer periods.
文摘Introduction-Objective: COVID-19 is a highly transmissible but often mild viral infection. However, some patients can present severe COVID-19 and subsequently die. The aim of the present study was to assess the risk factors for COVID-19 related death during the first three waves of the disease at the Epidemic Treatment Center (ETC) of Dakar Principal Hospital (DPH). Method: We conducted a descriptive and analytical perspective survival study from April 4, 2020 to September 25, 2021, including adult patients with COVID-19, hospitalized at the ETC of DPH. Log Rank test and multivariate Cox model were performed to identify risk factors for death. Results: We included 556 COVID-19 patients with mean age of 57 ± 17 years and a male-to-female ratio of 1.26. The number of deaths during one month of follow-up was 41, representing a cumulative risk of 7.4%. The log Rank test showed that being from the third wave (p = 0.0056), advanced age (p = 0.00098), presence of at least one comorbidity (p = 0.034), High blood pressure (p = 0.024), d-dimer level ≥ 1000 IU/L (p Conclusion: Our study showed that elderly and third-wave of COVID-19 patients were more at risk to die. Knowledge of risk factors for COVID-19 related death could improve the prognosis of these patients.
基金financially supported by the National Fundamental Research Program of Ministry of Science & Technology,China (Grant No. 2010CB951202)
文摘In this study, a flume experiment was designed to investigate the characteristics of wave-induced pore water pressure in the soil of a silty seabed with different clay contents, soil layer buried depths and wave heights respectively. The study showed that water waves propagating over silty seabed can induce significant change of pore water pressure, and the amplitude of pore pressure depends on depth of buried soil layer, clay content and wave height, which are considered as the three influencing factors for pore water pressure change. The pressure will attenuate according to exponential law with increase of soil layer buried depth, and the attenuation being more rapid in those soil layers with higher clay content and greater wave height. The pore pressure in silty seabed increases rapidly in the initial stage of wave action, then decreases gradually to a stable value, depending on the depth of buried soil layer, clay content and wave height. The peak value of pore pressure will increase if clay content or depth of buried soil layer decreases, or wave height increases. The analysis indicated that these soils with 5% clay content and waves with higher wave height produce instability in bed easier, and that the wave energy is mostly dissipated near the surface of soils and 5% clay content in soils can prevent pore pressure from dissipating immediately.
文摘Rationale: In the literature, some risk factors for severity and mortality from COVID-19 have been indicated. However, these factors can change, depending on the characteristics of the population and health services. In this sense, longitudinal studies can be useful for understanding local realities and subsidizing health actions based on these realities. Objective: To analyze the risk factors for severity and death in hospitalized patients with COVID-19. Methods: A retrospective cohort of patients with COVID-19 hospitalized from August 1 to October 16, 2021 (3<sup>rd</sup> wave of the pandemic), notified by the Department of Epidemiological Surveillance of Sao Tome and Principe. We employed measures of strength of associations for the analysis of exposure risk factors. Results: We analyzed 110 hospitalized patients (31.8% severe-critical and 68.2% non-severe). The risk factors for severe forms of COVID-19 were: being aged ≥60 years (RR = 3.3), being male (RR = 2), having comorbidities (RR = 2) and the risk increases to 10-fold for multicomorbidities, with emphasis on obesity, neoplasia, skin-muscle-surgical infection, dementia and to some degree CVD. 62.9% of patients with severe forms of the disease were not vaccinated. Risk factors for death among hospitalized and severe/critical cases, respectively, were having comorbidities (RR = 8 and 2.4) multicomorbidities (RR = 10 and 2.8 for those with 2 comorbidities and RR = 33.3 and 4 for those with 3 or 4 comorbidities), especially diabetes, dementia, neoplasia, cutaneous-muscular infection, and obesity. Although CVD was not associated with risk factors for death, these were the most frequently found among the severely hospitalized and deaths. In addition, important risk factors associated with death were not using corticoids (RR = 3.3, 230-fold risk) and not using anticoagulants-heparin (RR = 1.3, 30% risk) more compared to the severe cases that did use them. Most of the patients who died (63.2%) were not vaccinated. Moreover, having only 1 dose of the vaccine was a risk factor 1.9 times more for death among all hospitalized patients, but in the severe cases, there was no association between the variable vaccination and death. Among those hospitalized with 2 doses, it was a 0.5-fold protective factor among those hospitalized. The Delta variant of Sarscov-2 was the one found among severe cases and deaths investigated by genetic sequencing, with more exuberant clinical features compared to the other 2 previous vaccinations. Conclusion: Being elderly, male and presenting comorbidities, mainly multicomorbidities were the main characteristics associated with severity of COVID-19. On the other hand, comorbidities, and even worse, multicomorbidities, hospitalization for respiratory failure, lowered level of consciousness, no use of corticoid and no use of anticoagulation in critically ill patients, and not having at least 2 doses of vaccine for covid-19, were characteristics associated with death by COVID-19. These results will help inform healthcare providers so that the best interventions can be implemented to improve outcomes for patients with COVID-19. Public health interventions must be carefully tailored and implemented in these susceptible groups to reduce the risk of mortality in patients with COVID-19 and then the risk of major complications. Intensive and regular follow-up is needed to detect early occurrences of clinical conditions.
文摘The method of complex function and the method of Green's function are used to investigate the problem of SH-wave scattering by radial cracks of any limited length along the radius originating at the boundary of an elliptical hole, and the solution of dynamic stress intensity factor at the crack tip was given. A Green's function was constructed for the problem, which is a basic solution of displacement field for an elastic half space containing a half elliptical gap impacted by anti-plane harmonic linear source force at any point of its horizontal boundary. With division of a crack technique, a series of integral equations can be established on the conditions of continuity and the solution of dynamic stress intensity factor can be obtained. The influence of an elliptical hole on the dynamic stress intensity factor at the crack tip was discussed.
文摘One-dimensional ring power system is discredited to a number of nodes each containing a generator with internal reactance and load branch of resistance and reactance with a certain power factor. When a disturbance occurs at any machine in the power system, simulative analysis is performed to verify how the variation of load power factor affecting the behavior of electromechanical wave propagation by using the MATLAB package, from which different situations are presented and discussed. These results show the type of load has no effect on the behavior of electromechanical wave propagation.
文摘背景:疼痛是膝骨关节炎的主要症状,严重影响老年患者的生活质量。膝骨关节炎疼痛机制复杂,涉及多组织、多学科,需要可视化分析了解其主要内容与研究热点。目的:运用文献计量学可视化软件分析归纳膝骨关节炎疼痛领域的前沿内容和研究热点。方法:从Web of Science核心合集(Web of Science Core Collection,WoSCC)中检索2014-2024年膝骨关节炎疼痛领域的相关文献,运用Citespace、VOSviewer和Bibliometrix R-package三个可视化软件进行文献计量与可视化分析。结果与结论:①膝骨关节炎疼痛研究的发文量呈现逐年递增的趋势;②美国、中国、澳大利亚是该领域10年内发文量排名前三的国家;波士顿大学、悉尼大学、弗洛里达大学是发文量前三的科研机构;《OSTEOARTHRITIS AND CARTILAGE》是出版该领域文献最多的期刊,《PAIN》则是该领域被引次数最多的期刊;发文量最多的作者是Fillingim Roger B,该领域的核心作者之间已经建立了一些稳定的团队,但国际性合作尚有欠缺;③膝骨关节炎疼痛患者的日常管理(运动、心理、智能管理)、疼痛的炎症机制、蛋白组学、联合用药、中枢敏化和疼痛调节是膝骨关节炎疼痛研究的重点内容;人工智能辅助、体外冲击波疗法、射频消融术、神经冷冻术、关节腔内注射血液或细胞制剂可能是该领域的研究前沿。
基金The National Natural Science Foundation of China under contract No.51079082the Natural Science Foundation of Shanghai City under contract No.14ZR1419600+1 种基金the Research Innovation Projects of 2013 Shanghai Postgraduate under contract No.20131129the Top Discipline Project of Shanghai Municipal Education Commission
文摘Since the wind wave model Simulating Waves Nearshore (SWAN) cannot effectively simulate the wave fields near the lateral boundaries, the change characteristics and the distortion ranges of calculated wave factors including wave heights, periods, directions, and lengths near the lateral boundaries of calculation domain are carefully studied in the case of different water depths and wind speeds respectively. The calculation results show that the effects of the variety of water depth and wind speed on the modeled different wave factors near the lateral boundaries are different. In the case of a certain wind speed, the greater the water depth is, the greater the distortion range is. In the case of a certain water depth, the distortion ranges defined by the relative errors of wave heights, periods, and lengths are different from those defined by the absolute errors of the corresponding wave factors. Moreover, the distortion ranges defined by the relative errors decrease with the increase of wind speed; whereas the distortion ranges defined by the absolute errors change a little with the variety of wind speed. The distortion range of wave direction decreases with the increase of wind speed. The calculated wave factors near the lateral boundaries with the SWAN model in the actual physical areas, such as Lake Taihu and Lake Dianshan considered in this study, are indeed distorted if the calculation domains are not enlarged on the basis of actual physical areas. Therefore, when SWAN is employed to calculate the wind wave fields near the shorelines of sea or inland lakes, the appropriate approaches must be adopted to reduce the calculation errors.
基金Supported by National Nature Science of Foundation of China under Grant Nos. 10747005, 10847140the Natural Science of Lanzhou University of Technology under Grant No. Q200706
文摘Spiral wave could be observed in the excitable media, the neurons are often excitable within appropriateparameters. The appearance and formation of spiral wave in the cardiac tissue is linked to monomorphic ventriculartachycardia that can denervate into polymorphic tachycardia and ventricular fibrillation. The neuronal system oftenconsists of a large number of neurons with complex connections. In this paper, we theoretically study the transitionfrom spiral wave to spiral turbulence and homogeneous state (death of spiral wave) in two-dimensional array of theHindmarsh-Rose neuron with completely nearest-neighbor connections. In our numerical studies, a stable rotating spiralwave is developed and selected as the initial state, then the bifurcation parameters are changed to different values toobserve the transition from spiral wave to homogeneous state, breakup of spiral wave and weak change of spiral wave,respectively. A statistical factor of synchronization is defined with the mean field theory to analyze the transition fromspiral wave to other spatial states, and the snapshots of the membrane potentials of all neurons and time series of meanmembrane potentials of all neurons are also plotted to discuss the change of spiral wave. It is found that the sharpchanging points in the curve for factor of synchronization vs. bifurcation parameter indicate sudden transition fromspiral wave to other states. And the results are independent of the number of neurons we used.
基金The authors acknowledge the financial supports from the National Natural Science Foundation of China under grant No.90305005,50135030
文摘Structure health monitoring based on diagnostic Lamb waves has been found to be one of the most promising techniques recently. This paper has a brief review of the new developments on this method including the basic novel of the method, fundamentals and mathematics of Lamb wave propagation, narrowband and wideband Lamb wave excitation methods, optimization of excitation factors and diagnostic Lamb wave interpretation methods.
基金The National Key Research and Development Program of China under contract No.2017YFC1405600the National Natural Science Foundation of China under contract No.41476001
文摘The parameter inversion of internal solitary waves (ISWs) based on optical remote sensing images is a key work. A new approach is proposed and demonstrated for simulating the optical remote sensing images of ISWs with a smooth surface in the laboratory. An optical remote sensing simulation system used to detect ISWs is constructed by a two-dimensional ISW flume, a LED (light emitting diode) light source and two CCD (charge coupled device) cameras. The optical remote sensing images of the horizontal surface and ISWs propagation images of a vertical side are detected simultaneously, which aims to explore the response of optical remote sensing corresponding to ISWs with the smooth surface. The results show that during the propagation of ISWs, dark pattern images are obtained by CCD 1 camera. The characteristics of the dark patterns vary along with the incident angle of the light source. The characteristic parameters of the optical remote sensing images correspond to the wave factors of vertical profiles. The experiment also shows a positive correlation between the dark pattern width and the half wave width under different amplitudes of ISWs. The system has the advantages of clear phenomenon and high repeatability, which provides the scientific basis for quantitative investigation on imaging mechanism of ISW by optical remote sensing.
文摘Three methods for studying wave groups and their main parameters for describing wave groupiness are reviewed in this paper. Then they are analyzed and compared combined with field data from both aspects of group height and group length. A method and two parameters that can describe wave groupiness are suggested. The groupiness parameters of sea waves at three field stations are given. The effects of groupiness on both distributions of the wave height and the phase of component waves are investigated. The effects of datum length on the calculated value of grouping parameters are also discussed.
文摘Retaining walls have been used in many construction projects such as for road and inclined surfaces protection. The damage caused by an earthquake depends on the fundamental frequency, amplitude and the duration of the seismic motion. These parameters strongly depend on the seismic properties of the layers that are near the surface. In the study of retaining walls, in addition to the infl uence of soil, the infl uence of topography is also important. In the present study, site response analysis is performed by using fi nite element software PLAXIS to obtain the eff ect of various factors such as embedded length of the sheet pile, underground water table, length and angle of the nail, shear wave velocity of soil on site eff ect and dynamic response. Moreover, for better understanding of the eff ect of the above parameters, the stability analysis was performed by using shear reduction method. The results show that an increase in the embedded length of the sheet pile and the length of nailing causes an increase in the amplifi cation factor. Moreover, for shear-wave velocity in the range of 200- 600 m/s, the amplifi cation factor increases with increase of the shear-wave velocity due to the decrease of nonlinear behavior.
文摘The stability problem is a very important aspect in seismic wave numerical modeling. Based on the theory of seismic waves and constitutive equations of viscoelastic models, the stability problems of finite difference scheme for Kelvin- Voigt and Maxwell models with rectangular grids are analyzed. Expressions of stability conditions with arbitrary spatial accuracies for two viscoelastic models are derived. With approximation of quality factor Q≥5, simplified expressions are developed and some numerical models are given to verify the validity of the corresponding theoretical results. Then this paper summarizes the influences of seismic wave velocity, frequency, size of grid and difference coefficients, as well as quality factor on stability condition. Finally the prerequisite conditions of the simplified stability equations are given with error analysis.
基金National Natural Science Foundation of China(50468003)State 973 Project(2002 CB412706).
文摘In this paper, according to the relationship of observation spectrum with source spectrum, travel-path attenuation factor and site effect, we use the digital seismic data of moderate-small earthquakes to invert the soft rock site effect and S wave inelastic attenuation under the constraint of site effect, and determine the parameters of path and site. The parameters obtained by this method exclude the topographic effect of seismic stations, and truly reflect the seismic effect of free soft rock sites and the S wave inelastic attenuation in the studied region. The average soft rock site effect is about 1.5 times in the frequency domain of 2-4 Hz and the S wave quality factor is obtained as Qs=278f0.346, which can be directly applied to the stochastic modeling of ground motions in the studied region.
文摘A one-layer time-invariant eddy viscosity model is specified to develop a mathematical model for describing the essential features of the turbulent wave boundary layer over a rough bed. The functional form of the eddy viscosity is evaluated based on computational results from a two-equation turbulence model in which the eddy viscosity varies with time and space. The present eddy viscosity model simplifies much of the mathematical complexity in many existing models. Predictions from the present model have been compared with a wide range of experimental data. It is found that the eddy viscosity model adopted in the present study is physically reasonable.