3D traveltime calculation is widely used in seismic exploration technologies such as seismic migration and tomography. The fast marching method (FMM) is useful for calculating 3D traveltime and has proven to be effi...3D traveltime calculation is widely used in seismic exploration technologies such as seismic migration and tomography. The fast marching method (FMM) is useful for calculating 3D traveltime and has proven to be efficient and stable. However, it has low calculation accuracy near the source, which thus gives it low overall accuracy. This paper proposes a joint traveltime calculation method to solve this problem. The method firstly employs the wavefront construction method (WFC), which has a higher calculation accuracy than FMM in calculating traveltime in the small area near the source, and secondly adopts FMM to calculate traveltime for the remaining grid nodes. Due to the increase in calculation precision of grid nodes near the source, this new algorithm is shown to have good calculation precision while maintaining the high calculation efficiency of FMM, which is employed in most of the computational area. Results are verified using various numerical models.展开更多
On the basis of Hartmann Shack sensor imaging analysis, a new method is presented with which the wavefront slope can be obtained when the object is incoherent and extended. This method, which is demonstrated by both ...On the basis of Hartmann Shack sensor imaging analysis, a new method is presented with which the wavefront slope can be obtained when the object is incoherent and extended. This method, which is demonstrated by both theoretical interpreting and computer simulation, explains how to measure the wavefront slope difference between two sub apertures through the determination of image displacements on detector plane. It includes a fast and accurate digital algorithm for detecting wavefront disturbance, which is much suitable for realization in such electrical hardwares as digital signal processors.展开更多
Wavefront aberration affects the quality of retinal image directly. This paper reviews the representation and reconstruction of wavefront aberration, as well as the construction of virtual eye model based on Zernike p...Wavefront aberration affects the quality of retinal image directly. This paper reviews the representation and reconstruction of wavefront aberration, as well as the construction of virtual eye model based on Zernike polynomial coefficients. In addition, the promising prospect of virtual eye model is emphasized.展开更多
AIM: To evaluate and compare the efficacy of the astigmatic correction achieved with laser in situ keratomileusis(LASIK) in eyes with myopic astigmatism using wavefront-guided(WFG) and wavefront-optimized(WFO) ...AIM: To evaluate and compare the efficacy of the astigmatic correction achieved with laser in situ keratomileusis(LASIK) in eyes with myopic astigmatism using wavefront-guided(WFG) and wavefront-optimized(WFO) ablation profiles.METHODS: Prospective study included 221 eyes undergoing LASIK: 99 and 122 eyes with low and moderate myopic astigmatism(low and moderate myopia groups).Two subgroups were differentiated in each group according to the ablation profile: WFG subgroup,109 eyes(45/64,low/moderate myopia groups) treated using the Advanced Custom Vue platform(Abbott Medical Optics Inc.),and WFO subgroup,112 eyes(54/58,low/moderate myopia groups) treated using the EX-500 platform(Alcon).Clinical outcomes were evaluated during a 6-month follow-up,including a vector analysis of astigmatic changes.RESULTS: Significantly better postoperative uncorrected visual acuity and efficacy index was found in the WFG subgroups of each group(P≤0.041).Postoperative spherical equivalent and cylinder were significantly higher in WFO subgroups(P≤0.003).In moderate myopia group,a higher percentage of eyes with a postoperative cylinder ≤0.25 D was found in the WFG subgroup(90.6% vs 65.5%,P=0.002).In low and moderate myopia groups,the difference vector was significantly higher in the WFO subgroup compared to WFG(P〈0.001).In moderate myopia group,the magnitude(P=0.008) and angle of error(P〈0.001) were also significantly higher in the WFO subgroup.Significantlyless induction of high order aberrations were found with WFG treatments in both low and moderate myopia groups(P≤0.006).CONCLUSION: A more efficacious correction of myopic astigmatism providing a better visual outcome is achieved with WFG LASIK compared to WFO LASIK.展开更多
Among all kinds of wavefront control algorithms in adaptive optics systems, the direct gradient wavefront control algorithm is the most widespread and common method. This control algorithm obtains the actuator voltage...Among all kinds of wavefront control algorithms in adaptive optics systems, the direct gradient wavefront control algorithm is the most widespread and common method. This control algorithm obtains the actuator voltages directly from wavefront slopes through pre-measuring the relational matrix between deformable mirror actuators and Hartmann wavefront sensor with perfect real-time characteristic and stability. However, with increasing the number of sub-apertures in wavefront sensor and deformable mirror actuators of adaptive optics systems, the matrix operation in direct gradient algorithm takes too much time, which becomes a major factor influencing control effect of adaptive optics systems. In this paper we apply an iterative wavefront control algorithm to high-resolution adaptive optics systems, in which the voltages of each actuator are obtained through iteration arithmetic, which gains great advantage in calculation and storage. For AO system with thousands of actuators, the computational complexity estimate is about O(n2) ~ O(n3) in direct gradient wavefront control algorithm, while the computational complexity estimate in iterative wavefront control algorithm is about O(n) ~(O(n)3/2), in which n is the number of actuators of AO system. And the more the numbers of sub-apertures and deformable mirror actuators, the more significant advantage the iterative wavefront control algorithm exhibits.展开更多
Two types of handshaking circuits are proposed to implement the asynchronous communication between two processing elements in the wavefront array processors. After correcting the flaws in the original design, these ci...Two types of handshaking circuits are proposed to implement the asynchronous communication between two processing elements in the wavefront array processors. After correcting the flaws in the original design, these circuits make the system more robust and flexible. These circuits have compact architectures and are of higher performance. Besides, compared with other handshaking circuits, these designs are more suitable for FPGA.展开更多
While propagating inside the strongly scattering biological tssue,photons lose their incident directions beyond one transport mean free path(TMFP,~1 millimeter(mm)),which makes it challenging to achieve optical focusi...While propagating inside the strongly scattering biological tssue,photons lose their incident directions beyond one transport mean free path(TMFP,~1 millimeter(mm)),which makes it challenging to achieve optical focusing or clear imaging deep inside tissue.By manipulating many degrees of the incident optical wavefront,the latest optical wavefront engineering(WFE)technology compensates the wavelfront distortions caused by the scattering media and thus is toward breaking this physical limit,bringing bright perspective to many applications deep inside tissue,eg,high resolution functional/molecular imaging,optical excitation(optogenetics)and optical tweezers.However,inside the dynamic turbid media such as the biological tissue,the wavefront distortion is a fast and continuously changing process whose decorrelation rate is on timescales from milliseconds(ms)to microseconds(μs),or even faster.This requires that the WFE technology should be capable of beating this rapid process.In this review,we discuss the major challenges faced by the WFE technology due to the fast decorrelation of dynamic turbid media such as living tissue when achieving light focusing/imaging and summarize the research progress achieved to date to overcome these challenges.展开更多
This paper is concerned with the stability of traveling wavefronts for a population dynamics model with time delay. Combining the weighted energy method and the comparison principle, the global exponential stability o...This paper is concerned with the stability of traveling wavefronts for a population dynamics model with time delay. Combining the weighted energy method and the comparison principle, the global exponential stability of noncritical traveling wavefronts (waves with speeds c 〉 c*, where c=c* is the minimal speed) is established, when the initial perturbations around the wavefront decays to zero exponentially in space as x → -∞, but it can be allowed arbitrary large in other locations, which improves the results in[9, 18, 21].展开更多
Wavefront shaping(WFS)techniques have been used as a powerful tool to control light propagation in complex media,including multimode fibers.In this paper,we propose a new application of WFS for multimode fber-based se...Wavefront shaping(WFS)techniques have been used as a powerful tool to control light propagation in complex media,including multimode fibers.In this paper,we propose a new application of WFS for multimode fber-based sensors.The use of a single multimode fiber alone,without any special fabrication,as a sensor based on the light intensity variations is not an easy task.The twist effect on multimode fiber is used as an example herein.Experimental results show that light intensity through the multimode fiber shows no direct relationship with the twist angle,but the correlation coefficient(CC)of speckle patterns does.Moreover,if WFS is applied to transform the spatially seemingly random light pattern at the exit of the multimode fiber into an optical focus.The focal pattern correlation and intensity both can serve to gauge the twist angle,with doubled measurement range and allowance of using a fast point detector to provide the feedback.With further development,WFS may find potentials to facilitate the development of multimode fber-based sensors in a variety of scenarios.展开更多
Feedback-based wavefront shaping focuses light through scattering media by employing phase optimization algorithms.Genetic algorithms(GAs),inspired by the process of natural selection,are well suited for phase optimiz...Feedback-based wavefront shaping focuses light through scattering media by employing phase optimization algorithms.Genetic algorithms(GAs),inspired by the process of natural selection,are well suited for phase optimization in wavelfront shaping problems.In 2012,Conkey et al.first introduced a GA into feedback-based wavefront shaping to find the optimum phase map.Since then,due to its siuperior performance in noisy environment,the GA has been widely adopted by lots of implementations.However,there have been limited studies discussing and optimizing the detailed procedures of the GA.To fill this blank,in this study,we performed a thorough study on the performance of the GA for focusing light through scattering media.Using numerical tools,we evaluated certain procedures that can be potentially improved and provided guidance on how to choose certain parameters appropriately.This study is beneficial in improving the performance of wavefront shaping systems with GAs.展开更多
We demonstrate a modified particle swarm optimization(PSO) algorithm to effectively shape the incident light with strong robustness and short optimization time. The performance of the modified PSO algorithm and geneti...We demonstrate a modified particle swarm optimization(PSO) algorithm to effectively shape the incident light with strong robustness and short optimization time. The performance of the modified PSO algorithm and genetic algorithm(GA) is numerically simulated. Then, using a high speed digital micromirror device, we carry out light focusing experiments with the modified PSO algorithm and GA. The experimental results show that the modified PSO algorithm has greater robustness and faster convergence speed than GA. This modified PSO algorithm has great application prospects in optical focusing and imaging inside in vivo biological tissue, which possesses a complicated background.展开更多
The phase diversity wavefront sensor is one of the tools used to estimate wavefront aberration, and it is often used as a wavefront sensor in adaptive optics systems. However, the performance of the traditional phase ...The phase diversity wavefront sensor is one of the tools used to estimate wavefront aberration, and it is often used as a wavefront sensor in adaptive optics systems. However, the performance of the traditional phase diversity wavefront sensor is limited by the accuracy and dynamic ranges of the intensity distribution at the focus and defocus positions of the CCD camera. In this paper, a modified phase diversity wavefront sensor based on a diffraction grating is proposed to improve the ability to measure the wavefront aberration with larger amplitude and higher spatial frequency. The basic principle and the optics construction of the proposed method are also described in detail. The noise propagation property of the proposed method is also analysed by using the numerical simulation method, and comparison between the diffraction grating phase diversity wavefront sensor and the traditional phase diversity wavefront sensor is also made. The simulation results show that the diffraction grating phase diversity wavefront sensor can obviously improve the ability to measure the wavefront aberration, especially the wavefront aberration with larger amplitude and higher spatial frequency.展开更多
AIM: To compare the wavefront aberrations and corneal surface regularity between dry eye(DE) patients and normal subjects and assess its diagnostic performance for DE measured with OPD Scan-Ⅲ.METHODS: Fifty right eye...AIM: To compare the wavefront aberrations and corneal surface regularity between dry eye(DE) patients and normal subjects and assess its diagnostic performance for DE measured with OPD Scan-Ⅲ.METHODS: Fifty right eyes of 50 DE patients and 31 right eyes of normal subjects were included.The examinations for ocular surface including logarithm of the minimum angle of resolution best-corrected distance visual acuity(logMAR BCVA) the ocular surface disease index(OSDI), tear film break-up time(TBUT) and corneal fluorescein staining(CFS).OPD Scan-Ⅲ was used to measure anterior corneal aberrations including total corneal aberrations, high order aberration(HOA), coma, trefoil, spherical aberration(SA), standard deviation of corneal power(SDP), surface regularity index(SRI) and surface asymmetry index(SAI).Statistical analysis were assessed with nonparametric tests and Spearman’s correlations.All parameters were also analyzed for sensitivity, specificity, and receiver operating characteristics(ROC) curves.RESULTS: Wavefront aberrations parameters including total corneal aberrations, HOA, coma, trefoil, and SA in DE group were significantly higher than those in normal group(P<0.001).Corneal surface regularity parameters including SRI and SAI in DE group were significantly higher than both in normal group(P<0.05).All the wavefront aberrations parameters had significant correlations with ocular surface parameters(P<0.05).The logMAR BCVA had positive correlations with SAI and SRI(all P<0.001).CFS scores had positive correlations with SAI and SRI(all P<0.001).All the wavefront aberrations parameters showed good diagnosis sensitivity and specificity, however, the corneal regularity parameters showed only good specificity but poor sensitivity.The cut-off value selected for trefoil in diagnosis DE showed the highest area under the curve(AUC, 0.921) values as compared to the other parameters with sensitivity of 0.955 and specificity of 0.867.CONCLUSION: Wavefront aberrations and corneal surface regularity are increased in DE patients and also correlated with ocular surface parameters.Wavefront aberrations parameters have potential to be indicators to diagnosis and monitor DE.展开更多
This note is devoted to the son's blowflies equation with diffusion, a critical speed of traveling waves, we give behavior with respect to the mature age study on the traveling wavefronts to the Nicholtime-delayed re...This note is devoted to the son's blowflies equation with diffusion, a critical speed of traveling waves, we give behavior with respect to the mature age study on the traveling wavefronts to the Nicholtime-delayed reaction-diffusion equation. For the a detailed analysis on its location and asymptotic展开更多
By manipulating the phase map of a wavefront of light using a spatial light modulator,the scattered light can be sharply focused on a specific target.Several iterative optimization algo-rithrns for obtaining the optim...By manipulating the phase map of a wavefront of light using a spatial light modulator,the scattered light can be sharply focused on a specific target.Several iterative optimization algo-rithrns for obtaining the optimumn phase map have been explored.However,there has not been a comparative study on the performance of these algorithms.In this paper,six optimization algorithms for wavefront shaping inchuding continuous sequential,partitioning algorithm,transmission matrix estimation method,particle swarm optimization,genetic algorithm(GA),and simulated annealing(SA)are discussed and compared based on their efficiency when introduced with various measurement noise levels.展开更多
AIM: To compare and calculate the 3-year refractive results, higher-order aberrations (HOAs), contrast sensitivity (CS) and dry eye parameters after small incision lenticule extraction (SMILE) and wavefront-gui...AIM: To compare and calculate the 3-year refractive results, higher-order aberrations (HOAs), contrast sensitivity (CS) and dry eye parameters after small incision lenticule extraction (SMILE) and wavefront-guided femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) for correction of high myopia and myopic astigmatism. METHODS: In this prospective, non-randomized comparative study, 78 eyes with spherical equivalent (SE) of -8.11±1.09 diopters (D) received a SMILE surgery, and 65 eyes with SE of -8.05±1.12 D received a wavefront-guided FS-LASIK surgery with the VisuMax femtosecond laser (Carl Zeiss Meditec, Jena, Germany) for flap cutting. Visual acuity, manifest refraction, CS, HOAs, ocular surface disease index (OSDI) and tear break-up time (TBUT) were evaluated during a 3-year follow-up. RESULTS: The difference of uncorrected distance visual acuity (UDVA) postoperatively was achieved at lmo and at 3mo, whereas the difference of the mean UDVA between two groups at 3y were not statistically significant (t=-1.59, P=-0.13). The postoperative change of SE was 0.89 D in the FS-LASIK group (t=5.76, P=0.00), and 0.14 D in the SMILE group (t=-0.54, P=0.59) from lmo to 3y after surgery. At 3-year postoperatively, both HOAs and spherical aberrations in the SMILE group were obviously less than those in the FS-LASIK group (P=0.00), but the coma root mean square (RMS) was higher in the SMILE group (0.59±0.26) than in the FS-LASIK group (0.29±0.14, P=0.00). The mesopic CS values between two groups were not statistically significant at 3y postoperatively. Compared with the FS-LASIK group, lower OSDI scores and longer TBUT values were found in the SMILE group at Imo and 3mo postoperatively. With regard to safety, no eye lost any line of CDVA in both groups at 3y after surgery. CONCLUSION: Both SMILE and wavefront-guided FS- LASIK procedures provide good visual outcomes. Both procedures are effective and safe, but SMILE surgery achieve more stable long-term refractive outcome and better control of early postoperative dry eye as compared to FS-LASIK.展开更多
By applying the wavefront coding technique to an optical system, the depth of focus can be greatly increased. Several complicated methods, such as Fisher Information based method, have already been taken to optimize f...By applying the wavefront coding technique to an optical system, the depth of focus can be greatly increased. Several complicated methods, such as Fisher Information based method, have already been taken to optimize for the best pupil phase mask in ideal condition. Here one simple point spread function (PSF) based method with only the standard deviation method used to evaluate the PSF stability over the depth of focus is taken to optimize for the best coefficients of pupil phase mask in practical optical systems. Results of imaging simulations for optical systems with and without pupil phase mask are presented, and the sharpness of image is calculated for comparison. The optimized results showed better and much more stable imaging quality over the original system without changing the position of the image plane.展开更多
We studied the evolution of wavefront aberration(WFA) of a signal beam during amplification in a Ti:sapphire chirped pulse amplification(CPA) system. The results verified that the WFA of the amplified laser beam has l...We studied the evolution of wavefront aberration(WFA) of a signal beam during amplification in a Ti:sapphire chirped pulse amplification(CPA) system. The results verified that the WFA of the amplified laser beam has little relation with the change of the pump beam energies. Transverse parasitic lasing that might occur in CPA hardly affects the wavefront of the signal beam. Thermal effects were also considered in this study, and the results show that the thermal effect cumulated in multiple amplification processes also has no obvious influence on the wavefront of the signal beam for a single-shot frequency. The results presented in this paper confirmed experimentally that the amplification in a Ti:sapphire CPA system has little impact on the WFA of the signal beam and it is very helpful for wavefront correction of single-shot PW and multi-PW laser systems based on Ti:sapphire.展开更多
We propose a new algorithm for wavefront sensing based on binary intensity modulation. The algorithm is based on the fact that a wavefront can be expended with a series of orthogonal and binary functions, the Walsh se...We propose a new algorithm for wavefront sensing based on binary intensity modulation. The algorithm is based on the fact that a wavefront can be expended with a series of orthogonal and binary functions, the Walsh series. We use a spatial light modulator(SLM) to produce different binary-intensity-modulation patterns which are the simple linear transformation of the Walsh series. The optical fields under different binary-intensity-modulation patterns are detected with a photodiode.The relationships between the incident wavefront modulated with the patterns and their optical fields are built to determinate the coefficients of the Walsh series. More detailed and strict relationship equations are established with the algorithm by adding new modulation patterns according to the properties of the Walsh functions. An exact value can be acquired by solving the equations. Finally, with the help of phase unwrapping and smoothing, the wavefront can be reconstructed. The advantage of the algorithm is providing an analytical solution for the coefficients of the Walsh series to reconstruct the wavefront. The simulation experiments are presented and the effectiveness of the algorithm is demonstrated.展开更多
基金supported by NSFC(Nos.41274120,41404085,and 41504084)
文摘3D traveltime calculation is widely used in seismic exploration technologies such as seismic migration and tomography. The fast marching method (FMM) is useful for calculating 3D traveltime and has proven to be efficient and stable. However, it has low calculation accuracy near the source, which thus gives it low overall accuracy. This paper proposes a joint traveltime calculation method to solve this problem. The method firstly employs the wavefront construction method (WFC), which has a higher calculation accuracy than FMM in calculating traveltime in the small area near the source, and secondly adopts FMM to calculate traveltime for the remaining grid nodes. Due to the increase in calculation precision of grid nodes near the source, this new algorithm is shown to have good calculation precision while maintaining the high calculation efficiency of FMM, which is employed in most of the computational area. Results are verified using various numerical models.
文摘On the basis of Hartmann Shack sensor imaging analysis, a new method is presented with which the wavefront slope can be obtained when the object is incoherent and extended. This method, which is demonstrated by both theoretical interpreting and computer simulation, explains how to measure the wavefront slope difference between two sub apertures through the determination of image displacements on detector plane. It includes a fast and accurate digital algorithm for detecting wavefront disturbance, which is much suitable for realization in such electrical hardwares as digital signal processors.
基金National Natural Science Foundation of China (No. 61173182, No. 61179071)Applied Basic Research Project (No. 2011JY0124)International Cooperation and Exchange Project of Sichuan Province (No.2012HH0004)
文摘Wavefront aberration affects the quality of retinal image directly. This paper reviews the representation and reconstruction of wavefront aberration, as well as the construction of virtual eye model based on Zernike polynomial coefficients. In addition, the promising prospect of virtual eye model is emphasized.
基金Partially supported by a grant from Abbott Medical Optics
文摘AIM: To evaluate and compare the efficacy of the astigmatic correction achieved with laser in situ keratomileusis(LASIK) in eyes with myopic astigmatism using wavefront-guided(WFG) and wavefront-optimized(WFO) ablation profiles.METHODS: Prospective study included 221 eyes undergoing LASIK: 99 and 122 eyes with low and moderate myopic astigmatism(low and moderate myopia groups).Two subgroups were differentiated in each group according to the ablation profile: WFG subgroup,109 eyes(45/64,low/moderate myopia groups) treated using the Advanced Custom Vue platform(Abbott Medical Optics Inc.),and WFO subgroup,112 eyes(54/58,low/moderate myopia groups) treated using the EX-500 platform(Alcon).Clinical outcomes were evaluated during a 6-month follow-up,including a vector analysis of astigmatic changes.RESULTS: Significantly better postoperative uncorrected visual acuity and efficacy index was found in the WFG subgroups of each group(P≤0.041).Postoperative spherical equivalent and cylinder were significantly higher in WFO subgroups(P≤0.003).In moderate myopia group,a higher percentage of eyes with a postoperative cylinder ≤0.25 D was found in the WFG subgroup(90.6% vs 65.5%,P=0.002).In low and moderate myopia groups,the difference vector was significantly higher in the WFO subgroup compared to WFG(P〈0.001).In moderate myopia group,the magnitude(P=0.008) and angle of error(P〈0.001) were also significantly higher in the WFO subgroup.Significantlyless induction of high order aberrations were found with WFG treatments in both low and moderate myopia groups(P≤0.006).CONCLUSION: A more efficacious correction of myopic astigmatism providing a better visual outcome is achieved with WFG LASIK compared to WFO LASIK.
基金supported by the National Key Scientific and Research Equipment Development Project of China(Grant No.ZDYZ2013-2)the National Natural Science Foundation of China(Grant No.11173008)the Sichuan Provincial Outstanding Youth Academic Technology Leaders Program,China(Grant No.2012JQ0012)
文摘Among all kinds of wavefront control algorithms in adaptive optics systems, the direct gradient wavefront control algorithm is the most widespread and common method. This control algorithm obtains the actuator voltages directly from wavefront slopes through pre-measuring the relational matrix between deformable mirror actuators and Hartmann wavefront sensor with perfect real-time characteristic and stability. However, with increasing the number of sub-apertures in wavefront sensor and deformable mirror actuators of adaptive optics systems, the matrix operation in direct gradient algorithm takes too much time, which becomes a major factor influencing control effect of adaptive optics systems. In this paper we apply an iterative wavefront control algorithm to high-resolution adaptive optics systems, in which the voltages of each actuator are obtained through iteration arithmetic, which gains great advantage in calculation and storage. For AO system with thousands of actuators, the computational complexity estimate is about O(n2) ~ O(n3) in direct gradient wavefront control algorithm, while the computational complexity estimate in iterative wavefront control algorithm is about O(n) ~(O(n)3/2), in which n is the number of actuators of AO system. And the more the numbers of sub-apertures and deformable mirror actuators, the more significant advantage the iterative wavefront control algorithm exhibits.
文摘Two types of handshaking circuits are proposed to implement the asynchronous communication between two processing elements in the wavefront array processors. After correcting the flaws in the original design, these circuits make the system more robust and flexible. These circuits have compact architectures and are of higher performance. Besides, compared with other handshaking circuits, these designs are more suitable for FPGA.
文摘While propagating inside the strongly scattering biological tssue,photons lose their incident directions beyond one transport mean free path(TMFP,~1 millimeter(mm)),which makes it challenging to achieve optical focusing or clear imaging deep inside tissue.By manipulating many degrees of the incident optical wavefront,the latest optical wavefront engineering(WFE)technology compensates the wavelfront distortions caused by the scattering media and thus is toward breaking this physical limit,bringing bright perspective to many applications deep inside tissue,eg,high resolution functional/molecular imaging,optical excitation(optogenetics)and optical tweezers.However,inside the dynamic turbid media such as the biological tissue,the wavefront distortion is a fast and continuously changing process whose decorrelation rate is on timescales from milliseconds(ms)to microseconds(μs),or even faster.This requires that the WFE technology should be capable of beating this rapid process.In this review,we discuss the major challenges faced by the WFE technology due to the fast decorrelation of dynamic turbid media such as living tissue when achieving light focusing/imaging and summarize the research progress achieved to date to overcome these challenges.
基金supported by NSF of China(11401478)Gansu Provincial Natural Science Foundation(145RJZA220)
文摘This paper is concerned with the stability of traveling wavefronts for a population dynamics model with time delay. Combining the weighted energy method and the comparison principle, the global exponential stability of noncritical traveling wavefronts (waves with speeds c 〉 c*, where c=c* is the minimal speed) is established, when the initial perturbations around the wavefront decays to zero exponentially in space as x → -∞, but it can be allowed arbitrary large in other locations, which improves the results in[9, 18, 21].
基金supported by the Shenzhen Science and Technology Innovation Commission(No.JCYJ20170818104421564)the Hong Kong Innovation and Technology Commission(No.ITS/022/18)+1 种基金the Hong Kong Research Grant Council(No.25204416)the National Natural Science Foundation of China(Nos.81671726 and 81627805).
文摘Wavefront shaping(WFS)techniques have been used as a powerful tool to control light propagation in complex media,including multimode fibers.In this paper,we propose a new application of WFS for multimode fber-based sensors.The use of a single multimode fiber alone,without any special fabrication,as a sensor based on the light intensity variations is not an easy task.The twist effect on multimode fiber is used as an example herein.Experimental results show that light intensity through the multimode fiber shows no direct relationship with the twist angle,but the correlation coefficient(CC)of speckle patterns does.Moreover,if WFS is applied to transform the spatially seemingly random light pattern at the exit of the multimode fiber into an optical focus.The focal pattern correlation and intensity both can serve to gauge the twist angle,with doubled measurement range and allowance of using a fast point detector to provide the feedback.With further development,WFS may find potentials to facilitate the development of multimode fber-based sensors in a variety of scenarios.
文摘Feedback-based wavefront shaping focuses light through scattering media by employing phase optimization algorithms.Genetic algorithms(GAs),inspired by the process of natural selection,are well suited for phase optimization in wavelfront shaping problems.In 2012,Conkey et al.first introduced a GA into feedback-based wavefront shaping to find the optimum phase map.Since then,due to its siuperior performance in noisy environment,the GA has been widely adopted by lots of implementations.However,there have been limited studies discussing and optimizing the detailed procedures of the GA.To fill this blank,in this study,we performed a thorough study on the performance of the GA for focusing light through scattering media.Using numerical tools,we evaluated certain procedures that can be potentially improved and provided guidance on how to choose certain parameters appropriately.This study is beneficial in improving the performance of wavefront shaping systems with GAs.
基金Supported by the National Key Research and Development Program of China under Grant No 2017YFB1104500the Natural Science Foundation of Beijing under Grant No 7182091,the National Natural Science Foundation of China under Grant No 21627813the Fundamental Research Funds for the Central Universities under Grant No PYBZ1801
文摘We demonstrate a modified particle swarm optimization(PSO) algorithm to effectively shape the incident light with strong robustness and short optimization time. The performance of the modified PSO algorithm and genetic algorithm(GA) is numerically simulated. Then, using a high speed digital micromirror device, we carry out light focusing experiments with the modified PSO algorithm and GA. The experimental results show that the modified PSO algorithm has greater robustness and faster convergence speed than GA. This modified PSO algorithm has great application prospects in optical focusing and imaging inside in vivo biological tissue, which possesses a complicated background.
文摘The phase diversity wavefront sensor is one of the tools used to estimate wavefront aberration, and it is often used as a wavefront sensor in adaptive optics systems. However, the performance of the traditional phase diversity wavefront sensor is limited by the accuracy and dynamic ranges of the intensity distribution at the focus and defocus positions of the CCD camera. In this paper, a modified phase diversity wavefront sensor based on a diffraction grating is proposed to improve the ability to measure the wavefront aberration with larger amplitude and higher spatial frequency. The basic principle and the optics construction of the proposed method are also described in detail. The noise propagation property of the proposed method is also analysed by using the numerical simulation method, and comparison between the diffraction grating phase diversity wavefront sensor and the traditional phase diversity wavefront sensor is also made. The simulation results show that the diffraction grating phase diversity wavefront sensor can obviously improve the ability to measure the wavefront aberration, especially the wavefront aberration with larger amplitude and higher spatial frequency.
文摘AIM: To compare the wavefront aberrations and corneal surface regularity between dry eye(DE) patients and normal subjects and assess its diagnostic performance for DE measured with OPD Scan-Ⅲ.METHODS: Fifty right eyes of 50 DE patients and 31 right eyes of normal subjects were included.The examinations for ocular surface including logarithm of the minimum angle of resolution best-corrected distance visual acuity(logMAR BCVA) the ocular surface disease index(OSDI), tear film break-up time(TBUT) and corneal fluorescein staining(CFS).OPD Scan-Ⅲ was used to measure anterior corneal aberrations including total corneal aberrations, high order aberration(HOA), coma, trefoil, spherical aberration(SA), standard deviation of corneal power(SDP), surface regularity index(SRI) and surface asymmetry index(SAI).Statistical analysis were assessed with nonparametric tests and Spearman’s correlations.All parameters were also analyzed for sensitivity, specificity, and receiver operating characteristics(ROC) curves.RESULTS: Wavefront aberrations parameters including total corneal aberrations, HOA, coma, trefoil, and SA in DE group were significantly higher than those in normal group(P<0.001).Corneal surface regularity parameters including SRI and SAI in DE group were significantly higher than both in normal group(P<0.05).All the wavefront aberrations parameters had significant correlations with ocular surface parameters(P<0.05).The logMAR BCVA had positive correlations with SAI and SRI(all P<0.001).CFS scores had positive correlations with SAI and SRI(all P<0.001).All the wavefront aberrations parameters showed good diagnosis sensitivity and specificity, however, the corneal regularity parameters showed only good specificity but poor sensitivity.The cut-off value selected for trefoil in diagnosis DE showed the highest area under the curve(AUC, 0.921) values as compared to the other parameters with sensitivity of 0.955 and specificity of 0.867.CONCLUSION: Wavefront aberrations and corneal surface regularity are increased in DE patients and also correlated with ocular surface parameters.Wavefront aberrations parameters have potential to be indicators to diagnosis and monitor DE.
基金supported by Natural Sciences and Engineering Research Council of Canada under the NSERC grant RGPIN 354724-08
文摘This note is devoted to the son's blowflies equation with diffusion, a critical speed of traveling waves, we give behavior with respect to the mature age study on the traveling wavefronts to the Nicholtime-delayed reaction-diffusion equation. For the a detailed analysis on its location and asymptotic
文摘By manipulating the phase map of a wavefront of light using a spatial light modulator,the scattered light can be sharply focused on a specific target.Several iterative optimization algo-rithrns for obtaining the optimumn phase map have been explored.However,there has not been a comparative study on the performance of these algorithms.In this paper,six optimization algorithms for wavefront shaping inchuding continuous sequential,partitioning algorithm,transmission matrix estimation method,particle swarm optimization,genetic algorithm(GA),and simulated annealing(SA)are discussed and compared based on their efficiency when introduced with various measurement noise levels.
文摘AIM: To compare and calculate the 3-year refractive results, higher-order aberrations (HOAs), contrast sensitivity (CS) and dry eye parameters after small incision lenticule extraction (SMILE) and wavefront-guided femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) for correction of high myopia and myopic astigmatism. METHODS: In this prospective, non-randomized comparative study, 78 eyes with spherical equivalent (SE) of -8.11±1.09 diopters (D) received a SMILE surgery, and 65 eyes with SE of -8.05±1.12 D received a wavefront-guided FS-LASIK surgery with the VisuMax femtosecond laser (Carl Zeiss Meditec, Jena, Germany) for flap cutting. Visual acuity, manifest refraction, CS, HOAs, ocular surface disease index (OSDI) and tear break-up time (TBUT) were evaluated during a 3-year follow-up. RESULTS: The difference of uncorrected distance visual acuity (UDVA) postoperatively was achieved at lmo and at 3mo, whereas the difference of the mean UDVA between two groups at 3y were not statistically significant (t=-1.59, P=-0.13). The postoperative change of SE was 0.89 D in the FS-LASIK group (t=5.76, P=0.00), and 0.14 D in the SMILE group (t=-0.54, P=0.59) from lmo to 3y after surgery. At 3-year postoperatively, both HOAs and spherical aberrations in the SMILE group were obviously less than those in the FS-LASIK group (P=0.00), but the coma root mean square (RMS) was higher in the SMILE group (0.59±0.26) than in the FS-LASIK group (0.29±0.14, P=0.00). The mesopic CS values between two groups were not statistically significant at 3y postoperatively. Compared with the FS-LASIK group, lower OSDI scores and longer TBUT values were found in the SMILE group at Imo and 3mo postoperatively. With regard to safety, no eye lost any line of CDVA in both groups at 3y after surgery. CONCLUSION: Both SMILE and wavefront-guided FS- LASIK procedures provide good visual outcomes. Both procedures are effective and safe, but SMILE surgery achieve more stable long-term refractive outcome and better control of early postoperative dry eye as compared to FS-LASIK.
文摘By applying the wavefront coding technique to an optical system, the depth of focus can be greatly increased. Several complicated methods, such as Fisher Information based method, have already been taken to optimize for the best pupil phase mask in ideal condition. Here one simple point spread function (PSF) based method with only the standard deviation method used to evaluate the PSF stability over the depth of focus is taken to optimize for the best coefficients of pupil phase mask in practical optical systems. Results of imaging simulations for optical systems with and without pupil phase mask are presented, and the sharpness of image is calculated for comparison. The optimized results showed better and much more stable imaging quality over the original system without changing the position of the image plane.
基金Project supported by the National Natural Science Foundation of China(Grant No.61775223)the Strategic Priority Research Program of Chinese Academy of Sciences(Grant No.XDB1603)
文摘We studied the evolution of wavefront aberration(WFA) of a signal beam during amplification in a Ti:sapphire chirped pulse amplification(CPA) system. The results verified that the WFA of the amplified laser beam has little relation with the change of the pump beam energies. Transverse parasitic lasing that might occur in CPA hardly affects the wavefront of the signal beam. Thermal effects were also considered in this study, and the results show that the thermal effect cumulated in multiple amplification processes also has no obvious influence on the wavefront of the signal beam for a single-shot frequency. The results presented in this paper confirmed experimentally that the amplification in a Ti:sapphire CPA system has little impact on the WFA of the signal beam and it is very helpful for wavefront correction of single-shot PW and multi-PW laser systems based on Ti:sapphire.
基金Project supported by the National Innovation Fund of Chinese Academy of Sciences(Grant No.CXJJ-16M208)the Preeminent Youth Fund of Sichuan Province,China(Grant No.2012JQ0012)the Outstanding Youth Science Fund of Chinese Academy of Sciences
文摘We propose a new algorithm for wavefront sensing based on binary intensity modulation. The algorithm is based on the fact that a wavefront can be expended with a series of orthogonal and binary functions, the Walsh series. We use a spatial light modulator(SLM) to produce different binary-intensity-modulation patterns which are the simple linear transformation of the Walsh series. The optical fields under different binary-intensity-modulation patterns are detected with a photodiode.The relationships between the incident wavefront modulated with the patterns and their optical fields are built to determinate the coefficients of the Walsh series. More detailed and strict relationship equations are established with the algorithm by adding new modulation patterns according to the properties of the Walsh functions. An exact value can be acquired by solving the equations. Finally, with the help of phase unwrapping and smoothing, the wavefront can be reconstructed. The advantage of the algorithm is providing an analytical solution for the coefficients of the Walsh series to reconstruct the wavefront. The simulation experiments are presented and the effectiveness of the algorithm is demonstrated.