Astrocytic calcium waves:unveiling their roles in sleep and arousal modulation

Neuron-astrocyte interactions are vital for the brain’s connectome.Understanding astrocyte activities is crucial for comprehending the complex neural network,particularly the population-level functions of neurons in different cortical states and associated behaviors in mammals.Studies on animal sleep and wakefulness have revealed distinct cortical synchrony patterns between neurons.Astrocytes,outnumbering neurons by nearly fivefold,support and regulate neuronal and synaptic function.Recent research on astrocyte activation during cortical state transitions has emphasized the influence of norepinephrine as a neurotransmitter and calcium waves as key components of ion channel signaling.This summary focuses on a few recent studies investigating astrocyte-neuron interactions in mouse models during sleep,wakefulness,and arousal levels,exploring the involvement of noradrenaline signaling,ion channels,and glutamatergic signaling in different cortical states.These findings highlight the significant impact of astrocytes on large-scale neuronal networks,influencing brain activity and responsiveness.Targeting astrocytic signaling pathways shows promise for treating sleep disorders and arousal dysregulation.More research is needed to understand astrocytic calcium signaling in different brain regions and its implications for dysregulated brain states,requiring future human studies to comprehensively investigate neuron-astrocyte interactions and pave the way for therapeutic interventions in sleep-and arousal-related disorders.

Modeling Near-Field Impulsive Waves Generated by Deformable Landslide Using the HBP Model Based on the SPH Method

Landslide-generated impulsive waves(LGWs)in reservoir areas can seriously threaten waterway safety as well as hu-man life and properties around the two side slopes.The risk reduction and mitigation of such a hazard require the accurate prediction of near-field wave characteristics,such as wave amplitude and run-up.However,near-field LGW involves complicated fluid-solid interactions.Furthermore,the wave characteristics are closely related to various aspects,including the geometry and physical features of the slide,river,and body of water.However,the empirical or analytical methods used for rough estimation cannot derive accurate results,especially for deformable landslides,due to their significant geometry changes during the sliding process.In this study,the near-field waves generated by deformable landslides were simulated by smoothed particle hydrodynamics(SPH)based on multi-phase flow.The deformable landslides were generalized as a kind of viscous flow by adopting the Herschel-Bulkley-Papanastasiou(HBP)-based nonNewtonian rheology model.The HBP model is capable of producing deformable landslide dynamics even though the high-speed sliding process is involved.In this study,an idealized experiment case originating from Lituya LGW and a practical case of Gongjiafang LGW were reproduced for verification and demonstration.The simulation results of both cases show satisfactory consistency with the experiment/investigation data in terms of landslide movement and near-field impulsive wave characteristics,thus indicating the applicability and accuracy of the proposed method.Finally,the effects of the HBP model’s rheological parameters on the landslide dynamics and near-field wave characteristics are discussed,providing a parameter calibration method along with sug-gestions for further applications.

Contrasts of bimodal tropical instability waves(TIWs)-induced wind stress perturbations in the Pacific Ocean among observations,ocean models,and coupled climate models

The coupling between wind stress perturbations and sea surface temperature(SST)perturbations induced by tropical instability waves(TIWs)in the Pacific Ocean has been revealed previously and proven crucial to both the atmosphere and ocean.However,an overlooked fact by previous studies is that the loosely defined“TIWs”actually consist of two modes,including the Yanai wave-based TIW on the equator(hereafter eTIW)and the Rossby wave-based TIW off the equator(hereafter vTIW).Hence,the individual feedbacks of the wind stress to the bimodal TIWs remain unexplored.In this study,individual coupling relationships are established for both eTIW and v TIW,including the relationship between the TIW-induced SST perturbations and two components of wind stress perturbations,and the relationship between the TIW-induced wind stress perturbation divergence(curl)and the downwind(crosswind)TIW-induced SST gradients.Results show that,due to different distributions of eTIW and vTIW,the coupling strength induced by the eTIW is stronger on the equator,and that by the vTIW is stronger off the equator.The results of any of eTIW and vTIW are higher than those of the loosely defined TIWs.We further investigated how well the coupling relationships remained in several widely recognized oceanic general circulation models and fully coupled climate models.However,the coupling relationships cannot be well represented in most numerical models.Finally,we confirmed that higher resolution usually corresponds to more accurate simulation.Therefore,the coupling models established in this study are complementary to previous research and can be used to refine the oceanic and coupled climate models.

Spatiotemporal variations of parameters of internal solitary waves in the northern South China Sea

The dynamic parameters for internal solitary waves(ISWs)derived from the extended Korteweg-de Vries(eKdV)equation play an important role in the understanding and prediction of ISWs.The spatiotemporal variations of the dynamic parameters of the ISWs in the northern South China Sea(SCS)were studied based on the reanalysis of long-term temperature and salinity datasets.The results for spectrum analysis show that there are definite geographical differences for the periodic variation of the parameters:in shallow water,all parameters vary with a wave period of one year,while in deep water wave components of the parameters at other frequencies exist.Using wavelet analysis,the wavelet power spectral densities in deep water exhibited an inter-annual variation pattern.For example,the wave component of the dispersion coefficient with a wave period of about half a year reached its power peak once every two years.Based on previous work,this inter-annual variation pattern was deduced to be caused by dynamic processes.In further work on the regulatory mechanisms,empirical orthogonal function(EOF)decomposition was performed.It was found that the modes of the dispersion coefficient have different geographical distributions,explaining the reason why the wave components in different frequencies appeared in different locations.The numerical simulation results confirm that the variations in the parameters of the ISWs derived from the eKdV equation could affect the waveforms significantly because of changes in the polarity of the ISWs.Therefore,the periodic variations of the dynamic parameters are related to the geographical location because of dynamic processes operating.

A case study of continental shelf waves in the northwestern South China Sea induced by winter storms in 2021

This study aims to investigate characteristics of continental shelf wave(CSW)on the northwestern continental shelf of the South China Sea(SCS)induced by winter storms in 2021.Mooring and cruise observations,tidal gauge data at stations Hong Kong,Zhapo and Qinglan and sea surface wind data from January 1 to February 28,2021 are used to examine the relationship between along-shelf wind and sea level fluctuation.Two events of CSWs driven by the along-shelf sea surface wind are detected from wavelet spectra of tidal gauge data.The signals are triply peaked at periods of 56 h,94 h and 180 h,propagating along the coast with phase speed ranging from 6.9 m/s to18.9 m/s.The dispersion relation shows their property of the Kelvin mode of CSW.We develop a simple method to estimate amplitude of sea surface fluctuation by along-shelf wind.The results are comparable with the observation data,suggesting it is effective.The mode 2 CSWs fits very well with the mooring current velocity data.The results from rare current help to understand wave-current interaction in the northwestern SCS.

Influence of topography on the fine structures of stratospheric gravity waves:An analysis using COSMIC-2 temperature data

We derive the potential energy of gravity waves(GWs)in the upper troposphere and stratosphere at 45°S-45°N from December 2019 to November 2022 by using temperature profiles retrieved from the Constellation Observing System for Meteorology,Ionosphere,and Climate-2(COSMIC-2)satellite.Owing to the dense sampling of COSMIC-2,in addition to the strong peaks of gravity wave potential energy(GWPE)above the Andes and Tibetan Plateau,we found weak peaks above the Rocky,Atlas,Caucasus,and Tianshan Mountains.The land-sea contrast is responsible for the longitudinal variations of the GWPE in the lower and upper stratosphere.At 40°N/S,the peaks were mainly above the topographic regions during the winter.At 20°N/S,the peaks were a slight distance away from the topographic regions and might be the combined effect of nontopographic GWs and mountain waves.Near the Equator,the peaks were mainly above the regions with the lowest sea level altitude and may have resulted from convection.Our results indicate that even above the local regions with lower sea level altitudes compared with the Andes and Tibetan Plateau,the GWPE also exhibits fine structures in geographic distributions.We found that dissipation layers above the tropopause jet provide the body force to generate secondary waves in the upper stratosphere,especially during the winter months of each hemisphere and at latitudes of greater than 20°N/S.

MAVEN observation of magnetosonic waves in the Martian magnetotail region

Magnetosonic waves are an important medium for energy transfer in collisionless space plasma.Magnetosonic waves have been widely investigated in the upstream of the bow shock at Mars.These waves are believed to originate from pickup ions or reflected particles.By utilizing MAVEN spacecraft data,we have observed the occurrence of quasi-perpendicularly propagating magnetosonic emissions near the proton gyrofrequency in the Martian magnetotail region.These plasma waves are associated with a significant enhancement of proton and oxygen flux.The excited magnetosonic waves could possibly heat the protons through resonance and facilitate the ionospheric plasma escape.Our results could be helpful to better understand the Mars’magnetospheric dynamics and offer insights into possible energy redistribution between waves and plasma in the Martian nightside magnetosphere.

Detection of Gravitational Waves with Semi Classical Features and Resulting Cosmological Implications

The author argues in this document that initial vacuum state values possibly responsible for GW generation in relic conditions in the initial onset of inflation may have a temporary unsqueezed, possibly even coherent initial value, which would permit in certain models classical coherent initial gravitational wave states. Furthermore, several arguments pro and con as to if or not initial relic GW should be high frequency will be presented, with the reason given why earlier string models did NOT favor low frequency relic GW from the big bang. What is observed is that large higher dimensions above our 4 Dimensional space time, if recipients of matter-energy from collapse and re birth of the universe are enough to insure low relic GW. The existence of higher dimensions, in itself if the additional dimensions are small and compact will have no capacity to lower the frequency limit values of relic GW, as predicted by Giovannini, et al. in 1995.

Experimental Study on the Identification of Scholte Waves Based on Acoustic Pressure Field Measurement

Scholte waves at the seafloor interface are generally identified by their velocity features and seismic fields,which are measured using ocean bottom seismometers and geophones.These methods are effective in cases where there is a considerable difference between the velocities of Scholte and acoustic waves in water.However,they are ineffective when the velocities of these two types of waves are close to each other.Thus,in this paper,a method based on acoustic pressure field measurement for identifying Scholte waves is proposed according to their excitation and propagation characteristics.The proposed method can overcome the limitations on the velocities of two types of waves.A tank experiment is designed and conducted according to the proposed method,and an ocean environment is scaled down to the laboratory size.Acoustic measurements are obtained along virtual arrays in the water column using a robotic apparatus.Experiments show that changes in Scholte wave amplitudes,depending on different source depths and propagation distances,are consistent with the theoretical results.This means that Scholte waves generated at the seafloor interface are successfully measured and identified in the acoustic pressure field.

Propagation Properties of Shock Waves in Polyurethane Foam based on Atomistic Simulations

Porous materials are widely used in the field of protection because of their excellent energy absorption characteristics.In this work,a series of polyurethane microscopic models are established and the effect of porosity on the shock waves is studied with classical molecular dynamics simulations.Firstly,shock Hugoniot relations for different porosities are obtained,which compare well with the experimental data.The pores collapse and form local stress wave,which results in the complex multi-wave structure of the shock wave.The microstructure analysis shows that the local stress increases and the local velocity decreases gradually during the process of pore collapse to complete compaction.Finally,it leads to stress relaxation and velocity homogenization.The shock stress peaks can be fitted with two exponential functions,and the amplitude of attenuation coefficient decreases with the increase of density.Besides,the pore collapse under shock or non-shock are discussed by the entropy increase rate of the system.The energy is dissipated mainly through the multiple interactions of the waves under shock.The energy is dissipated mainly by the friction between atoms under non-shock.

Ion-acoustic waves with non-planar wavefronts

The ion-acoustic(IA) mode exhibiting various orbital angular momentum(OAM) states is examined in a plasma with drifting electrons.The constituent plasma species are modeled with a non-gyrotropic Maxwellian distribution and discussion of dispersion relation and growth rate of twisted IA waves under various conditions is presented.In the domain of kinetic model,the twisted IA waves are characterized by Laguerre-Gaussian(LG) solutions,where plasma distribution function and electric field are decomposed into axial and azimuthal components.The plasma response function is obtained under paraxial approximations and investigated for threshold condition of instability growth rate with helical electric field structures.The impact of an extra electron specie on the instability is demonstrated through a comparison of twisted waves for single and double electron species.

Analytical solutions of turbulent boundary layer beneath forward-leaning waves

As a typical nonlinear wave,forward-leaning waves can be frequently encountered in the near-shore areas,which can impact coastal sediment transport significantly.Hence,it is of significance to describe the characteristics of the boundary layer beneath forward-leaning waves accurately,especially for the turbulent boundary layer.In this work,the linearized turbulent boundary layer model with a linear turbulent viscosity coefficient is applied,and the novel expression of the near-bed orbital velocity that has been worked out by the authors for forward-leaning waves of arbitrary forward-leaning degrees is further used to specify the free stream boundary condition of the bottom boundary layer.Then,a variable transformation is found so as to make the equation of the turbulent boundary layer model be solved analytically through a modified Bessel function.Consequently,an explicit analytical solution of the turbulent boundary layer beneath forward-leaning waves is derived by means of variable separation and variable transformation.The analytical solutions of the velocity profile and bottom shear stress of the turbulent boundary layer beneath forward-leaning waves are verified by comparing the present analytical results with typical experimental data available in the previous literature.

Experimental study on the variation of optical remote sensing imaging characteristics of internal solitary waves with wind speed

Optical remote sensing has been widely used to study internal solitary waves(ISWs).Wind speed has an important effect on ISW imaging of optical remote sensing.The light and dark bands of ISWs cannot be observed by optical remote sensing when the wind is too strong.The relationship between the characteristics of ISWs bands in optical remote sensing images and the wind speed is still unclear.The influence of wind speeds on the characteristics of the ISWs bands is investigated based on the physical simulation experiments with the wind speeds of 1.6,3.1,3.5,3.8,and 3.9 m/s.The experimental results show that when the wind speed is 3.9 m/s,the ISWs bands cannot be observed in optical remote sensing images with the stratification of h_(1)∶h_(2)=7∶58,ρ_(1)∶ρ_(2)=1∶1.04.When the wind speeds are 3.1,3.5,and 3.8 m/s,which is lower than 3.9 m/s,the ISWs bands can be obtained in the simulated optical remote sensing image.The location of the band’s dark and light extremum and the band’s peak-to-peak spacing are almost not affected by wind speed.More-significant wind speeds can cause a greater gray difference of the light-dark bands.This provided a scientific basis for further understanding of ISW optical remote sensing imaging.

Linear and Nonlinear Stokes Waves Theory: Numerical Hydrodynamic and Energy Studies

The increase of wave energy in electricity production is an objective shared by many countries to meet growing demand and global warming. To analyze devices capable of converting the energy of sea waves into electrical energy, it is important to master the various theories of gravity waves and generation. We will in our work consider a numerical waves tank for an amplitude A=0.5, a wavelength λ=0.25 , an average height He=10 and a Froude number fixed at 1 × 105. Numerical wave channel analysis is used to reproduce the natural phenomenon of wave propagation in an experimental model. Wave makers are usually used to generate waves in the channel. In theory, the influence of an incident wave can be considered, as in the case of our study. In this study, the evolution of the hydrodynamic parameters and the energy transported in one wavelength can be determined by calculation. A change of variable will be done in this work to facilitate the writing of the boundary conditions at the free surface and at the bottom. The nonlinear Stokes theory will be studied in this case in order to provide hydrodynamic solutions through the Navier-Stokes equations to finally deduce the energetic results. To do this, the finite difference method will be used for the hydrodynamic results such as the velocity potential and the free surface elevation and the trapezium method of Newton for the energetic results. Thus, we will determine the energetic potential according to the decrease in the slope of the tank. To do this, we will take as values of beta representing the inverse of the slope of the tank, β=100, β=105, β=110 and β=105. .

Gravitational Waves Background, as Well as Some UFO, FRB and Supernova Flares, Are Due to Compressibility of the Spacetime (CoST)

The recently observed gravitational wave background is explained in terms of the quantum modification of the general relativity (Qmoger). Some UFO, FRB and supernova flares also can be explained in terms of Qmoger.

Slow Strain Waves: Models and Observations, a Review

The theoretical discovery of slow strain (tectonic) waves, the so-called strain waves in the Earth, served as a motivation to develop physical backgrounds of the mathematical theory of propagation of these waves and to search for methods of their experimental detection. For fifty years, scientists from different countries in different regions of the Earth, using direct and indirect methods, discovered the migration of crustal deformation and revealed its wave nature, and, therefore, proved the reality of the existence of strain waves of the Earth. This overview briefly describes the history of the development of the concept of strain waves on the Earth, the observation methods and properties of strain waves, and the main types of geological structures generating these waves. The most prominent results of the theoretical, laboratory, and in-situ observations of slow strain migration, including slow earthquakes and periodic Episodic Tremor and Slow (ETS) slip effects, are presented. In the near future, studies of slow strain waves may lead to a fundamental revision of the current concepts about the physics of the seismic process.

Evaluation of soil fabric using elastic waves during load-unload

It is essential to assess the evolution of soil fabric as it has an important role in the mechanical responses of soils during complex loading conditions.This contribution carries out the physical experiments using three granular materials in the laboratory.The variations of compression and shear wave velocities(Vp and Vs)are investigated during load-unload cycles under dry and drained conditions.Supplementary discrete element method(DEM)simulations are performed to understand the evolution of soil fabric during the equivalent load-unload cycles using spherical particles.Vp and Vs are not always reversible even though the stress state regains its isotropic condition after unload,indicating that Vp and Vs are governed by not only the stress state but also the fabric change.The variations of Vp/Vs are density-and stress-dependent;a higher level of stress ratio(s01/s03)threshold is observed for denser packings to trigger a significant change in wave velocity ratio(Vp/Vs)for experimental results using spherical glass beads and simulation data using spherical particles.Considering the particle shape,a higher s01/s03 threshold is found for more angular particles than rounded particles.The DEM result reveals that Vp/Vs of spherical particles can be correlated linearly with the evolution of fabric ratio(Fver/Fhor)during loadunload in a pre-peak range under dry and drained conditions.

Generation of OAM Waves and Analysis of Mode Purity for 5G Sub-6 GHz Applications

This article presents the generation of Orbital AngularMomentum(OAM)vortex waves with mode 1 using Uniform Circular Array(UCA)antenna.Two different designs,namely,UCA-1(4-element array antenna)and UCA-2(8-element array antenna),were designed and fabricated using FR-4 substrate to generate OAM mode 1 at 3.5 GHz(5G mid-band).The proposed antenna arrays comprised rectangular microstrip patch elements with inset fed technique.The elements were excited by a carefully designed feeding phase shift network to provide similar output energy at output ports with desired phase shift value.The generated OAM waves were confirmed by measuring the null in the bore sight of their 2D radiation patterns,simulated phase distribution and intensity distribution.The measurement results agree well with the simulation results.Moreover,a detailed mode purity analysis of the generated OAM waves was carried out considering different factors.The investigation found that the greater the number of elements,the higher the purity of the generated OAM wave.Compared with other previous works,the proposed antenna design of this paper is very simple to design and fabricate.In addition,the proposed antennas are compact in design even at lower frequency band with very wide bandwidth to meet the requirements of 5G mid-band applications.

Study on the Propagation and Focusing Mechanism of Long Waves over A Submerged Atoll

An analytical solution for long waves propagating over a submerged atoll is established. The atolls involved in this study are annular coral reefs with large lagoons in the middle, and the expression of the cross section is a trinomial function of the radial distance, i.e., h=ar(2s)-br~s+h_0, where s is the positive rational number. This analytical solution extends the theory by Wang et al.(2018) as s is no longer limited to s=2/m, where m is the positive integer. In addition, by adjusting the terrain parameters properly, the analytic solution can be degenerated to describe the wave propagation over topography with a hump or pit. According to the relationship between wave rays and wave energy, the distribution characteristics and formation mechanism of energy over the topography are expounded. When the lagoon is non-existent, all wave rays converge at the x-axis, which results in an abrupt amplification of the wave amplitude around the convergence point. When a lagoon is mounted on the top of the atoll, the rays are scattered due to the refraction of the lagoon, and only some rays converge at the symmetrical axis and the ridges on both sides,which results in the amplification of wave amplitudes in these areas.

THE SHOCK WAVES FOR A MIXED-TYPE SYSTEM FROM CHEMOTAXIS

In this paper,we study the shock waves for a mixed-type system from chemotaxis.We are concerned with the jump conditions for the left state which is located in the elliptical region and the right state in the hyperbolic region.Under the generalized entropy conditions,we find that there are different shock wave structures for different parameters.To guarantee the uniqueness of the solutions,we obtain the admissible shock waves which satisfy the generalized entropy condition in both parameters.Finally,we construct the Riemann solutions in some solvable regions.