Daubechies interval cally weakly singular Fredholm kind. Utilizing the orthogonality equation is reduced into a linear wavelet is used to solve nurneriintegral equations of the second of the wavelet basis, the integra...Daubechies interval cally weakly singular Fredholm kind. Utilizing the orthogonality equation is reduced into a linear wavelet is used to solve nurneriintegral equations of the second of the wavelet basis, the integral system of equations. The vanishing moments of the wavelet make the wavelet coefficient matrices sparse, while the continuity of the derivative functions of basis overcomes naturally the singular problem of the integral solution. The uniform convergence of the approximate solution by the wavelet method is proved and the error bound is given. Finally, numerical example is presented to show the application of the wavelet method.展开更多
We obtain weak type (1, q) inequalities for fractional integral operators on generalized non-homogeneous Morrey spaces. The proofs use some properties of maximal operators. Our results are closely related to the str...We obtain weak type (1, q) inequalities for fractional integral operators on generalized non-homogeneous Morrey spaces. The proofs use some properties of maximal operators. Our results are closely related to the strong type inequalities in [13, 14, 15].展开更多
Numerous studies have shown that cell replacement therapy can replenish lost cells and rebuild neural circuitry in animal models of Parkinson’s disease.Transplantation of midbrain dopaminergic progenitor cells is a p...Numerous studies have shown that cell replacement therapy can replenish lost cells and rebuild neural circuitry in animal models of Parkinson’s disease.Transplantation of midbrain dopaminergic progenitor cells is a promising treatment for Parkinson’s disease.However,transplanted cells can be injured by mechanical damage during handling and by changes in the transplantation niche.Here,we developed a one-step biomanufacturing platform that uses small-aperture gelatin microcarriers to produce beads carrying midbrain dopaminergic progenitor cells.These beads allow midbrain dopaminergic progenitor cell differentiation and cryopreservation without digestion,effectively maintaining axonal integrity in vitro.Importantly,midbrain dopaminergic progenitor cell bead grafts showed increased survival and only mild immunoreactivity in vivo compared with suspended midbrain dopaminergic progenitor cell grafts.Overall,our findings show that these midbrain dopaminergic progenitor cell beads enhance the effectiveness of neuronal cell transplantation.展开更多
In this article, we use the Hausdorf distance to treat triple Simpson’s rule of the Henstock triple integral of a fuzzy valued function as well as the error bound of the method. We also introduce δ-fine subdivisions...In this article, we use the Hausdorf distance to treat triple Simpson’s rule of the Henstock triple integral of a fuzzy valued function as well as the error bound of the method. We also introduce δ-fine subdivisions for a Henstock triple integral and numerical example is presented in order to show the application and the consequence of the method.展开更多
The Owen’s T function is presented in four new ways, one of them as a series similar to the Euler’s arctangent series divided by 2π, which is its majorant series. All possibilities enable numerically stable ...The Owen’s T function is presented in four new ways, one of them as a series similar to the Euler’s arctangent series divided by 2π, which is its majorant series. All possibilities enable numerically stable and fast convergent computation of the bivariate normal integral with simple recursion. When tested computation on a random sample of one million parameter triplets with uniformly distributed components and using double precision arithmetic, the maximum absolute error was 3.45 × 10<sup>-</sup><sup>16</sup>. In additional testing, focusing on cases with correlation coefficients close to one in absolute value, when the computation may be very sensitive to small rounding errors, the accuracy was retained. In rare potentially critical cases, a simple adjustment to the computation procedure was performed—one potentially critical computation was replaced with two equivalent non-critical ones. All new series are suitable for vector and high-precision computation, assuming they are supplemented with appropriate efficient and accurate computation of the arctangent and standard normal cumulative distribution functions. They are implemented by the R package Phi2rho, available on CRAN. Its functions allow vector arguments and are ready to work with the Rmpfr package, which enables the use of arbitrary precision instead of double precision numbers. A special test with up to 1024-bit precision computation is also presented.展开更多
In this paper, by using the atomic decomposition of the weighted weak Hardy space WH;(R;), the authors discuss a class of multilinear oscillatory singular integrals and obtain their boundedness from the weighted wea...In this paper, by using the atomic decomposition of the weighted weak Hardy space WH;(R;), the authors discuss a class of multilinear oscillatory singular integrals and obtain their boundedness from the weighted weak Hardy space WH;(R;) to the weighted weak Lebesgue space WL;(R;) for ω∈A;(R;).展开更多
In this paper, a Darbao type random fixed point theorem for a system of weak continuous random operators with random domain is first proved. When, by using the theorem, some existence criteria of random solutions for ...In this paper, a Darbao type random fixed point theorem for a system of weak continuous random operators with random domain is first proved. When, by using the theorem, some existence criteria of random solutions for a systems of nonlinear random Volterra integral equations relative to the weak topology in Banach spaces are given. As applications, some existence theorems of weak random solutions for the random Cauchy problem of a system of nonlinear random differential equations are obtained, as well as the existence of extremal random solutions and random comparison results for these systems of random equations relative to weak topology in Banach spaces. The corresponding results of Szep, Mitchell-Smith, Cramer-Lakshmikantham, Lakshmikantham-Leela and Ding are improved and generalized by these theorems.展开更多
Understanding the neural underpinning of human gait and balance is one of the most pertinent challenges for 21st-century translational neuroscience due to the profound impact that falls and mobility disturbances have ...Understanding the neural underpinning of human gait and balance is one of the most pertinent challenges for 21st-century translational neuroscience due to the profound impact that falls and mobility disturbances have on our aging population.Posture and gait control does not happen automatically,as previously believed,but rather requires continuous involvement of central nervous mechanisms.To effectively exert control over the body,the brain must integrate multiple streams of sensory information,including visual,vestibular,and somatosensory signals.The mechanisms which underpin the integration of these multisensory signals are the principal topic of the present work.Existing multisensory integration theories focus on how failure of cognitive processes thought to be involved in multisensory integration leads to falls in older adults.Insufficient emphasis,however,has been placed on specific contributions of individual sensory modalities to multisensory integration processes and cross-modal interactions that occur between the sensory modalities in relation to gait and balance.In the present work,we review the contributions of somatosensory,visual,and vestibular modalities,along with their multisensory intersections to gait and balance in older adults and patients with Parkinson’s disease.We also review evidence of vestibular contributions to multisensory temporal binding windows,previously shown to be highly pertinent to fall risk in older adults.Lastly,we relate multisensory vestibular mechanisms to potential neural substrates,both at the level of neurobiology(concerning positron emission tomography imaging)and at the level of electrophysiology(concerning electroencephalography).We hope that this integrative review,drawing influence across multiple subdisciplines of neuroscience,paves the way for novel research directions and therapeutic neuromodulatory approaches,to improve the lives of older adults and patients with neurodegenerative diseases.展开更多
In this paper, the two-dimensional Marcinkewicz integral introduced by Stein μ(f)(x)=(∫_0~x|∫_(|x-y|≤1) _(|x-y|)^(Ω(x-y))f(y)dy|~2t^(-3)dt)~2 is shown to be of weak type (1,1) and weighted weak type (1,1) with r...In this paper, the two-dimensional Marcinkewicz integral introduced by Stein μ(f)(x)=(∫_0~x|∫_(|x-y|≤1) _(|x-y|)^(Ω(x-y))f(y)dy|~2t^(-3)dt)~2 is shown to be of weak type (1,1) and weighted weak type (1,1) with respect to power weight |x|~' if - 1< α< 0, where Ω is homogeneous of degree 0. has mean value 0 and belongs to Llog^+L(S^1).展开更多
Assume that D is a nuclear space and D' its strong topological dual space. Let {B_t}t∈(0,∞) be a Wiener D'-process. In this paper, the real-valued and D'-valued weak stochastic integral with respect to {...Assume that D is a nuclear space and D' its strong topological dual space. Let {B_t}t∈(0,∞) be a Wiener D'-process. In this paper, the real-valued and D'-valued weak stochastic integral with respect to {B_t} are established.AMS Subject Classification. 60H05.展开更多
In this paper, multidimensional weakly singular integrals are solved by using rectangular quadrature rules which base on quadrature rules of one dimensional weakly singular and multidimensional regular integrals with ...In this paper, multidimensional weakly singular integrals are solved by using rectangular quadrature rules which base on quadrature rules of one dimensional weakly singular and multidimensional regular integrals with their Euler-Maclaurin asymptotic expansions of the errors. The presented method is suit for solving multidimensional and singular integrals by comparing with Gauss quadrature rule. The error asymptotic expansions show that the convergence order of the initial quadrature rules is , where . The order of accuracy can reach to by using extrapolation and splitting extrapolation, where h0 is the maximum mesh width. Some numerical examples are constructed to show the efficiency of the method.展开更多
The SubBytes (S-box) transformation is the most crucial operation in the AES algorithm, significantly impacting the implementation performance of AES chips. To design a high-performance S-box, a segmented optimization...The SubBytes (S-box) transformation is the most crucial operation in the AES algorithm, significantly impacting the implementation performance of AES chips. To design a high-performance S-box, a segmented optimization implementation of the S-box is proposed based on the composite field inverse operation in this paper. This proposed S-box implementation is modeled using Verilog language and synthesized using Design Complier software under the premise of ensuring the correctness of the simulation result. The synthesis results show that, compared to several current S-box implementation schemes, the proposed implementation of the S-box significantly reduces the area overhead and critical path delay, then gets higher hardware efficiency. This provides strong support for realizing efficient and compact S-box ASIC designs.展开更多
Algorithm for Laplace ′s integral is given when the inverse image function has high order discontinui ty. The multi-node technique of B-spline is used to describe the interruption point, cusp and non-smooth point of...Algorithm for Laplace ′s integral is given when the inverse image function has high order discontinui ty. The multi-node technique of B-spline is used to describe the interruption point, cusp and non-smooth point of the inverse image function. The difference quotient and de Boor algorithm are used to derive the image function of the Lapl ace′s integral under non-uniform partition. And a set of practical formula is got when the partition is quasi-uniform. The scheme enables the image function to be approximated within any prescribed tolerance. Experiments also show that g ood result is achieved. It is much faster than that of Simpsons rule, and much s impler than that of Berge method, the traditional efficient method. It is no lon ger to find the zero points and coefficients of Gauss-Laguerre or Gauss-Legend re polynomials. The image function of Laplace′s integral can also be computed while the inverse image function is hyper-function with high order discontinuity.展开更多
基金Supported by the National Natural Science Foundation of China (60572048)the Natural Science Foundation of Guangdong Province(054006621)
文摘Daubechies interval cally weakly singular Fredholm kind. Utilizing the orthogonality equation is reduced into a linear wavelet is used to solve nurneriintegral equations of the second of the wavelet basis, the integral system of equations. The vanishing moments of the wavelet make the wavelet coefficient matrices sparse, while the continuity of the derivative functions of basis overcomes naturally the singular problem of the integral solution. The uniform convergence of the approximate solution by the wavelet method is proved and the error bound is given. Finally, numerical example is presented to show the application of the wavelet method.
基金Supported by Fundamental Research Program 2011-2012
文摘We obtain weak type (1, q) inequalities for fractional integral operators on generalized non-homogeneous Morrey spaces. The proofs use some properties of maximal operators. Our results are closely related to the strong type inequalities in [13, 14, 15].
基金supported by the National Key Research and Development Program of China,Nos.2017YFE0122900(to BH),2019YFA0110800(to WL),2019YFA0903802(to YW),2021YFA1101604(to LW),2018YFA0108502(to LF),and 2020YFA0804003(to JW)the National Natural Science Foundation of China,Nos.31621004(to WL,BH)and 31970821(to YW)+1 种基金CAS Project for Young Scientists in Basic Research,No.YSBR-041(to YW)Joint Funds of the National Natural Science Foundation of China,No.U21A20396(to BH)。
文摘Numerous studies have shown that cell replacement therapy can replenish lost cells and rebuild neural circuitry in animal models of Parkinson’s disease.Transplantation of midbrain dopaminergic progenitor cells is a promising treatment for Parkinson’s disease.However,transplanted cells can be injured by mechanical damage during handling and by changes in the transplantation niche.Here,we developed a one-step biomanufacturing platform that uses small-aperture gelatin microcarriers to produce beads carrying midbrain dopaminergic progenitor cells.These beads allow midbrain dopaminergic progenitor cell differentiation and cryopreservation without digestion,effectively maintaining axonal integrity in vitro.Importantly,midbrain dopaminergic progenitor cell bead grafts showed increased survival and only mild immunoreactivity in vivo compared with suspended midbrain dopaminergic progenitor cell grafts.Overall,our findings show that these midbrain dopaminergic progenitor cell beads enhance the effectiveness of neuronal cell transplantation.
文摘In this article, we use the Hausdorf distance to treat triple Simpson’s rule of the Henstock triple integral of a fuzzy valued function as well as the error bound of the method. We also introduce δ-fine subdivisions for a Henstock triple integral and numerical example is presented in order to show the application and the consequence of the method.
文摘The Owen’s T function is presented in four new ways, one of them as a series similar to the Euler’s arctangent series divided by 2π, which is its majorant series. All possibilities enable numerically stable and fast convergent computation of the bivariate normal integral with simple recursion. When tested computation on a random sample of one million parameter triplets with uniformly distributed components and using double precision arithmetic, the maximum absolute error was 3.45 × 10<sup>-</sup><sup>16</sup>. In additional testing, focusing on cases with correlation coefficients close to one in absolute value, when the computation may be very sensitive to small rounding errors, the accuracy was retained. In rare potentially critical cases, a simple adjustment to the computation procedure was performed—one potentially critical computation was replaced with two equivalent non-critical ones. All new series are suitable for vector and high-precision computation, assuming they are supplemented with appropriate efficient and accurate computation of the arctangent and standard normal cumulative distribution functions. They are implemented by the R package Phi2rho, available on CRAN. Its functions allow vector arguments and are ready to work with the Rmpfr package, which enables the use of arbitrary precision instead of double precision numbers. A special test with up to 1024-bit precision computation is also presented.
基金supported by the National Natural Science Foundation of China(Grant No.11501233)China Postdoctoral Science Foundation(No.2015M572327)+2 种基金Humanities and Social Sciences Program of the Ministry of Education(No.15YJC630053)Natural Science Foundation of Anhui Province(No.1408085MA08 and No.1508085SMA204)Natural Science Foundation of the Education Department of Anhui Province(No.KJ2015A335 and No.KJ2015A270)
文摘In this paper, by using the atomic decomposition of the weighted weak Hardy space WH;(R;), the authors discuss a class of multilinear oscillatory singular integrals and obtain their boundedness from the weighted weak Hardy space WH;(R;) to the weighted weak Lebesgue space WL;(R;) for ω∈A;(R;).
文摘In this paper, a Darbao type random fixed point theorem for a system of weak continuous random operators with random domain is first proved. When, by using the theorem, some existence criteria of random solutions for a systems of nonlinear random Volterra integral equations relative to the weak topology in Banach spaces are given. As applications, some existence theorems of weak random solutions for the random Cauchy problem of a system of nonlinear random differential equations are obtained, as well as the existence of extremal random solutions and random comparison results for these systems of random equations relative to weak topology in Banach spaces. The corresponding results of Szep, Mitchell-Smith, Cramer-Lakshmikantham, Lakshmikantham-Leela and Ding are improved and generalized by these theorems.
文摘Understanding the neural underpinning of human gait and balance is one of the most pertinent challenges for 21st-century translational neuroscience due to the profound impact that falls and mobility disturbances have on our aging population.Posture and gait control does not happen automatically,as previously believed,but rather requires continuous involvement of central nervous mechanisms.To effectively exert control over the body,the brain must integrate multiple streams of sensory information,including visual,vestibular,and somatosensory signals.The mechanisms which underpin the integration of these multisensory signals are the principal topic of the present work.Existing multisensory integration theories focus on how failure of cognitive processes thought to be involved in multisensory integration leads to falls in older adults.Insufficient emphasis,however,has been placed on specific contributions of individual sensory modalities to multisensory integration processes and cross-modal interactions that occur between the sensory modalities in relation to gait and balance.In the present work,we review the contributions of somatosensory,visual,and vestibular modalities,along with their multisensory intersections to gait and balance in older adults and patients with Parkinson’s disease.We also review evidence of vestibular contributions to multisensory temporal binding windows,previously shown to be highly pertinent to fall risk in older adults.Lastly,we relate multisensory vestibular mechanisms to potential neural substrates,both at the level of neurobiology(concerning positron emission tomography imaging)and at the level of electrophysiology(concerning electroencephalography).We hope that this integrative review,drawing influence across multiple subdisciplines of neuroscience,paves the way for novel research directions and therapeutic neuromodulatory approaches,to improve the lives of older adults and patients with neurodegenerative diseases.
文摘In this paper, the two-dimensional Marcinkewicz integral introduced by Stein μ(f)(x)=(∫_0~x|∫_(|x-y|≤1) _(|x-y|)^(Ω(x-y))f(y)dy|~2t^(-3)dt)~2 is shown to be of weak type (1,1) and weighted weak type (1,1) with respect to power weight |x|~' if - 1< α< 0, where Ω is homogeneous of degree 0. has mean value 0 and belongs to Llog^+L(S^1).
文摘Assume that D is a nuclear space and D' its strong topological dual space. Let {B_t}t∈(0,∞) be a Wiener D'-process. In this paper, the real-valued and D'-valued weak stochastic integral with respect to {B_t} are established.AMS Subject Classification. 60H05.
文摘In this paper, multidimensional weakly singular integrals are solved by using rectangular quadrature rules which base on quadrature rules of one dimensional weakly singular and multidimensional regular integrals with their Euler-Maclaurin asymptotic expansions of the errors. The presented method is suit for solving multidimensional and singular integrals by comparing with Gauss quadrature rule. The error asymptotic expansions show that the convergence order of the initial quadrature rules is , where . The order of accuracy can reach to by using extrapolation and splitting extrapolation, where h0 is the maximum mesh width. Some numerical examples are constructed to show the efficiency of the method.
文摘The SubBytes (S-box) transformation is the most crucial operation in the AES algorithm, significantly impacting the implementation performance of AES chips. To design a high-performance S-box, a segmented optimization implementation of the S-box is proposed based on the composite field inverse operation in this paper. This proposed S-box implementation is modeled using Verilog language and synthesized using Design Complier software under the premise of ensuring the correctness of the simulation result. The synthesis results show that, compared to several current S-box implementation schemes, the proposed implementation of the S-box significantly reduces the area overhead and critical path delay, then gets higher hardware efficiency. This provides strong support for realizing efficient and compact S-box ASIC designs.
文摘Algorithm for Laplace ′s integral is given when the inverse image function has high order discontinui ty. The multi-node technique of B-spline is used to describe the interruption point, cusp and non-smooth point of the inverse image function. The difference quotient and de Boor algorithm are used to derive the image function of the Lapl ace′s integral under non-uniform partition. And a set of practical formula is got when the partition is quasi-uniform. The scheme enables the image function to be approximated within any prescribed tolerance. Experiments also show that g ood result is achieved. It is much faster than that of Simpsons rule, and much s impler than that of Berge method, the traditional efficient method. It is no lon ger to find the zero points and coefficients of Gauss-Laguerre or Gauss-Legend re polynomials. The image function of Laplace′s integral can also be computed while the inverse image function is hyper-function with high order discontinuity.