For a discrete system, the idea that the orbit’s topological structure possesses three levels is proposed and the notions of the quasi-weakly almost periodic point and the minimal covering of a topological semi-conju...For a discrete system, the idea that the orbit’s topological structure possesses three levels is proposed and the notions of the quasi-weakly almost periodic point and the minimal covering of a topological semi-conjugacy are introduced. The relationship between the three levels and the recurrence of points and some properties kept under the topological semi-conjugacy is also discussed.展开更多
Alzheimer’s disease is a primary age-related neurodegenerative disorder that can result in impaired cognitive and memory functions.Although connections between changes in brain networks of Alzheimer’s disease patien...Alzheimer’s disease is a primary age-related neurodegenerative disorder that can result in impaired cognitive and memory functions.Although connections between changes in brain networks of Alzheimer’s disease patients have been established,the mechanisms that drive these alterations remain incompletely understood.This study,which was conducted in 2018 at Northeastern University in China,included data from 97 participants of the Alzheimer’s Disease Neuroimaging Initiative(ADNI)dataset covering genetics,imaging,and clinical data.All participants were divided into two groups:normal control(n=52;20 males and 32 females;mean age 73.90±4.72 years)and Alzheimer’s disease(n=45,23 males and 22 females;mean age 74.85±5.66).To uncover the wiring mechanisms that shaped changes in the topology of human brain networks of Alzheimer’s disease patients,we proposed a local naive Bayes brain network model based on graph theory.Our results showed that the proposed model provided an excellent fit to observe networks in all properties examined,including clustering coefficient,modularity,characteristic path length,network efficiency,betweenness,and degree distribution compared with empirical methods.This proposed model simulated the wiring changes in human brain networks between controls and Alzheimer’s disease patients.Our results demonstrate its utility in understanding relationships between brain tissue structure and cognitive or behavioral functions.The ADNI was performed in accordance with the Good Clinical Practice guidelines,US 21 CFR Part 50-Protection of Human Subjects,and Part 56-Institutional Review Boards(IRBs)/Research Good Clinical Practice guidelines Institutional Review Boards(IRBs)/Research Ethics Boards(REBs).展开更多
The genesis of physical particles is essentially a mystery. Quantum field theory creation operators provide an abstract mechanism by which particles come into existence, but quantum fields do not possess energy densit...The genesis of physical particles is essentially a mystery. Quantum field theory creation operators provide an abstract mechanism by which particles come into existence, but quantum fields do not possess energy density. I reference several recent treatments of this problem and develop ideas based on self-stabilizing field structures with focus on higher order self-induced self-stabilizing field structures. I extend this treatment in this paper to related issues of topological charge.展开更多
基金the Foundation of Guangdong Province and the Foundation of Advanced Research Zhongshan University
文摘For a discrete system, the idea that the orbit’s topological structure possesses three levels is proposed and the notions of the quasi-weakly almost periodic point and the minimal covering of a topological semi-conjugacy are introduced. The relationship between the three levels and the recurrence of points and some properties kept under the topological semi-conjugacy is also discussed.
基金Fundamental Research Funds for the Central Universities in China,No.N161608001 and No.N171903002
文摘Alzheimer’s disease is a primary age-related neurodegenerative disorder that can result in impaired cognitive and memory functions.Although connections between changes in brain networks of Alzheimer’s disease patients have been established,the mechanisms that drive these alterations remain incompletely understood.This study,which was conducted in 2018 at Northeastern University in China,included data from 97 participants of the Alzheimer’s Disease Neuroimaging Initiative(ADNI)dataset covering genetics,imaging,and clinical data.All participants were divided into two groups:normal control(n=52;20 males and 32 females;mean age 73.90±4.72 years)and Alzheimer’s disease(n=45,23 males and 22 females;mean age 74.85±5.66).To uncover the wiring mechanisms that shaped changes in the topology of human brain networks of Alzheimer’s disease patients,we proposed a local naive Bayes brain network model based on graph theory.Our results showed that the proposed model provided an excellent fit to observe networks in all properties examined,including clustering coefficient,modularity,characteristic path length,network efficiency,betweenness,and degree distribution compared with empirical methods.This proposed model simulated the wiring changes in human brain networks between controls and Alzheimer’s disease patients.Our results demonstrate its utility in understanding relationships between brain tissue structure and cognitive or behavioral functions.The ADNI was performed in accordance with the Good Clinical Practice guidelines,US 21 CFR Part 50-Protection of Human Subjects,and Part 56-Institutional Review Boards(IRBs)/Research Good Clinical Practice guidelines Institutional Review Boards(IRBs)/Research Ethics Boards(REBs).
文摘The genesis of physical particles is essentially a mystery. Quantum field theory creation operators provide an abstract mechanism by which particles come into existence, but quantum fields do not possess energy density. I reference several recent treatments of this problem and develop ideas based on self-stabilizing field structures with focus on higher order self-induced self-stabilizing field structures. I extend this treatment in this paper to related issues of topological charge.
