Effect of Chinese national holidays and weekends versus weekday admission on clinical outcomes in patients with STEMI undergoing primary PCI

Background Data regarding the influence of weekends and Chinese national holiday＇s admission on the outcomes of patients with ST-elevated myocardial infarction （STEMI） is lacking. This study sought to investigate the effect of Chinese national holidays and weekend admission on outcomes in patients with STEMI undergoing primary percutaneous coronary intervention （PPCI）. Methods Patients pre- senting with STEMI within 12 h of symptom onset who underwent PPCI were retrospectively enrolled. The primary outcome of in-hospital mortality and major adverse cardiovascular events in patients presenting Chinese national holiday＇s and weekends versus weekdays was evaluated. Results A total of 441 STEMI patients were enrolled in this study. Of these, 129 （29.3%） patients were admitted during Chinese national holidays and weekends and 312 （70.7%） during weekdays. Patients admitted during holidays and weekends were more likely to present with Killip class Ⅲ-Ⅳ. Patients admitted during holidays and weekends experienced a significantly longer door-to-baUoon time, symptom onset-to-door time as well as symptom onset-to-balloon time. The in-hospital mortality between patients presenting holidays and weekends versus weekdays was comparable. However, patients admitted during holidays and weekends have a signitieantly higher rate of in-hospital major adverse cardiovascular events. Multivariate analysis demonstrated that holidays and weekends admission was independ- ently associated with adverse outcomes. Conclusions In China, STEMI patients undergoing PPCI during national holidays and weekends have worse in-hospital outcomes compared to those admitted during weekdays. These findings suggest that continuous efforts should be undertaken to enhance the Chinese healthcare system and to ensure that comparable outcomes are achieved for all STEMI patients regardless of time of presentation.

How Do People in Shanghai Spend Their Weekends and Holidays?

学口语就是学习怎样用英文表达自己的观点。由于中文与英文的表述习惯不同,因而我们在用英文表达自己的观点时不免会带有某些中文表达法的痕迹,这是自然的,避免不了的。不过,我们在平时的学习和训练中却仍需去留意,并通过不断地模仿一些现成的说法。

Should Exams Be Given on Weekends?

China’s national college entrance exam,which is set down for June 7 and 8,occurred on Monday and Tuesday this year.The exam caused extensive traffic jams incities and many parents had to take two days off work to accompany their children to the exam.

Weekends

周末对于大家来说是非常宝贵的放松时间。请你根据以下所给提示,以Weekends为题,用英语介绍一下你的周末如何度过以及你对周末的看法。提示:1.周末对于人们来说意味着什么。2.每个人都有自己度周末的方式。3.你是怎样度周末的。

Weekend and nighttime effect on the prognosis of peptic ulcer bleeding

AIM:To evaluate whether weekend or nighttime admission affects prognosis of peptic ulcer bleeding despite early endoscopy.METHODS:Retrospective data collection from four referral centers,all of which had a formal out-of-hours emergency endoscopy service,even at weekends.A total of 388 patients with bleeding peptic ulcers who were admitted via the emergency room between January 2007 and December 2009 were enrolled.Analyzed parameters included time from patients' arrival until endoscopy,mortality,rebleeding,need for surgery and length of hospital stay.RESULTS:The weekday and weekend admission groups comprised 326 and 62 patients,respectively.There were no significant differences in baseline characteristics between the two groups,except for younger age in the weekend group.Most patients (97%) had undergone early endoscopy,which resulted in a low mortality rate regardless of point of presentation (1.8% overall vs 1.6% on the weekend).The only outcome that was worse in the weekend group was a higher rate of rebleeding (12% vs 21%,P = 0.030).However,multivariate analysis revealed nighttime admission and a high Rockall score (≥ 6) as significant independent risk factors for rebleeding,rather than weekend admission.CONCLUSION:Early endoscopy for peptic ulcer bleeding can prevent the weekend effect,and nighttime admission was identified as a novel risk factor for rebleeding,namely the nighttime effect.

Is there a weekend effect in hip fracture patients presenting to a United Kingdom teaching hospital?

AIM To compare mortality and time-to-surgery of patients admitted with hip fracture to our teaching hospital on weekdays vs weekends. METHODS Data was prospectively collected and retrospectively analysed for 816 hip fracture patients. Multivariate logistic regression was carried out on 3 binary outcomes(timeto-surgery < 36 h; 30-d mortality; 120-d mortality), using the explanatory variables time-of-admission; age; gender; American Society of Anesthesiologist(ASA) grade; abbreviated mental test score(AMTS); fracture type; accommodation admitted from; walking ability outdoors; accompaniment outdoors and season. RESULTS Baseline characteristics were not statistically different between those admitted on weekdays vs weekends. Weekend admission was not associated with an increased time-to-surgery(P = 0.975), 30-d mortality(P = 0.842) or 120-d mortality(P = 0.425). Gender(P = 0.028), ASA grade(P < 0.001), AMTS(P = 0.041) and accompaniment outdoors(P = 0.033) were significant covariates for 30-d mortality. Furthermore, age(P < 0.001),gender(P = 0.011), ASA grade(P < 0.001), AMTS(P < 0.001) and accompaniment outdoors(P = 0.033) all significantly influenced mortality at 120 d. ASA(P < 0.001) and season(P = 0.014) had significant effect on the odds of undergoing surgery in under 36 h.CONCLUSION Weekend admission was not associated with increased time-to-surgery or mortality in hip fracture patients. Demographic factors affect mortality in accordance with previous published reports.

Effect of weekend admission on geriatric hip fractures

BACKGROUND The care discrepancy for patients presenting to a hospital on the weekend relative to the work week is well documented.With respect to hip fractures,however,there is no consensus about the presence of a so-called“weekend effect”.This study sought to determine the effects,if any,of weekend admission on care of geriatric hip fractures admitted to a large tertiary care hospital.It was hypothesized that geriatric hip fracture patients admitted on a weekend would have longer times to medical optimization and surgery and increased complication and mortality rates relative to those admitted on a weekday.AIM To determine if weekend admission of geriatric hip fractures is associated with poor outcome measures and surgical delay.METHODS A retrospective chart review of operative geriatric hip fractures treated from 2015-2017 at a large tertiary care hospital was conducted.Two cohorts were compared:patients who arrived at the emergency department on a weekend,and those that arrived at the emergency department on a weekday.Primary outcome measures included mortality rate,complication rate,transfusion rate,and length of stay.Secondary outcome measures included time from emergency department arrival to surgery,time from emergency department arrival to medical optimization,and time from medical optimization to surgery.RESULTS There were no statistically significant differences in length of stay(P=0.2734),transfusion rate(P=0.9325),or mortality rate(P=0.3460)between the weekend and weekday cohorts.Complication rate was higher in patients who presented on a weekend compared to patients who presented on a weekday(13.3%vs 8.3%;P=0.044).Time from emergency department arrival to medical optimization(22.7 h vs 20.0 h;P=0.0015),time from medical optimization to surgery(13.9 h vs 10.8 h;P=0.0172),and time from emergency department arrival to surgery(42.7 h vs 32.5 h;P<0.0001)were all significantly longer in patients who presented to the hospital on a weekend compared to patients who presented to the hospital on a weekday.CONCLUSION This study provided insight into the“weekend effect”for geriatric hip fractures and found that day of presentation has a clinically significant impact on delivered care.

Variation in Parameters of Ambient Air Quality in National Capital Territory (NCT) of Delhi (India)

Air Pollution is an escalating problem worldwide fuelled by increasing anthropogenic activities, speedy development, rapid industrialization, transportation, superfluous use of fossil fuel consumption, increasing global power needs, etc. Also the diverse meteorological factors influence our environment to a great extent. Population explosion has led to remarkable increase in vehicular population. The use solely depends upon the lifestyle of the citizen. Any change in the lifestyle has a remarkable effect on the air we breathe. A comprehensive database for pollution levels from the year 2006 to 2010 was analyzed for a main traffic intersection and a non-traffic area in Delhi (India). The paper asserts that pollutant concentration levels on weekend are lower than those on weekdays (increase on Sundays with respect to weekdays is CO 2.98 times, PM2.5 1.18 times, NO 1.62 times, NO2 5.76 times, SO2 1.27 times and O3 1.15 times). The pollution levels have been found to attenuate on public holidays and weekends. Pollution can hence be related to the weekly cycle of human activities. Pollutions due to vehicular emissions on roads, rails, air or water all serve as major sources of pollution. Hence, viably possible solutions for pollution control can also be achieved by controlling the magnitude of traffic flow on roads.

Preventing physician quality of life from impinging on patient quality of care: Weakening the weekend effect

Imprecise or delayed care can reflect many factors, including straightforward difficulties in physician judgment and false negative tests. However, the movement toward decreasing physician work hours also leads to delays in care caused by inadequate staffing or inadequate communication between staffing, which must be addressed if quality of care is to remain high. The demonstration of delays in the management of anastomotic leaks over weekends or in association with false positive radiologic studies exemplifies this challenge.

EMISSIVENESS AND DESTINATION CHOICE BEHAVIOR OF SHANGHAINESE IN THEIR WEEKEND RECREATION

Based on questionnaire survey and cross--tabulation analysis, the authors discussed relationships between emissiveness and socio--economic elements ofShanghainese in their weekend trips, including emissivenesses of different age group,income per month, occupations, education and family structure. Visiting rates ofrecreationists to destinations demonstrated different levels even being under a same emissiveness. In the second part of the paper, the authors described three differentspatial scales of destination choice behavior of Shanghainese to tourist sites fromwhich situated in urban area, to which located in suburb area and in neighboringprovinces. The authors also observed the perceptive evaluation of Shanghainese tothose sites they had visited or would visit in the future. Some proposals abollt sustainable urban tourism development were put forward at the end of this paper.

Morphological and biochemical effects of weekend alcohol consumption in rats: Role of concentration and gender

AIM To examine the association between weekend alcohol consumption and the biochemical and histological alterations at two different concentrations of alcohol in both genders in rats.METHODS Wistar rats weighing 170-200 g were divided into groups as follows:(1) Control groups; and(2) weekend alcohol-consumption group: 2 d/weekly per 12 wk, at two different concentrations:(1) Group of males or females with a consumption of a solution of alcohol at 40%; and(2) group of males or females with a consumption of a solution of alcohol at 5%. At the end of the experiment, serum and liver samples were obtained. The following enzymes and metabolites were determined in serum: Alanine Aminotransferase(ALT), Aspartate Aminotransferase(AST), Lactate Dehydrogenase, and Gamma-Glutamyltransferase, and glucose, triglycerides, cholesterol, bilirubin, and albumin. Liver samples from each group were employed to analyze morphological abnormalities by light microscopy.RESULTS In all of the weekend alcohol-consumption groups, AST activity presented a significant, 10-fold rise. Regarding ALT activity, the groups with weekend alcohol consumption presented a significant increase that was six times greater. Bilirubin levels increased significantly in both groups of females. We observed a significant increase in the parameters of fatty change and inflammation due to weekend alcohol consumption. Only the group of females that consumed alcohol at 40% presented slight hepatocel ular disorganization CONCLUSION The results obtained herein provide solid evidence that weekend alcohol consumption gives rise to liver damage, demonstrated by biochemical and histological alterations, first manifested acutely, and prolonged weekend alcohol consumption can cause greater, irreversible damage.

Weekday vs weekend endoscopy: Is there a true difference in patient outcomes? A meta-analysis

AIM:To evaluate the"weekend effect"on outcomes in patient admitted on the weekend for upper gastrointestinal bleeding(UGIB).METHODS:A comprehensive search was performed(March 2014).Studies comparing weekend and weekday endoscopy in patients with UGIB were included.All studies had at least 2 of 3 primary outcomes which included:mortality,need for surgery,time to endoscopy,endoscopy on admission day,and length of hospital stay.Three authors individually extracted data.Metaanalysis was performed using pooled estimates with odds ratio or mean difference by fixed and random effects models.RESULTS:Eleven studies met the inclusion criteria.Patients admitted with UGIB on the weekend exhibited a statistically significant increase in mortality(OR=1.13;95%CI:1.06-1.20;P<0.01),need for surgery(OR=2.46;95%CI:1.51-3.99;P<0.01),and time to endoscopy(MD 2.68;95%CI:0.17-5.20;P=0.04)as compared to patients admitted with UGIB on a weekday.Furthermore,patients with UGIB admitted on weekend experienced statistically significant less endoscopy on day of admission(OR=0.72;95%CI:0.62-0.85;P<0.01).No difference was noted between the two groups for length of hospital stay(MD-1.29;95%CI:-3.03-0.45;P=0.15).CONCLUSION:A weekend effect seems to be apparent in patients with UGIB with significantly poorer outcomes.

Seasonal and Temporal Variations in Volatile Organic Compounds in Indoor and Outdoor Air in Al-Jahra City, Kuwait

Indoor and outdoor air samples were simultaneously collected from the largest office building in Jahra City during 57 sampling events between August 2010 and November 2011. The collected samples were analyzed for 78 volatile organic compounds (VOCs) using CO2 cryogenic preconcentration and GC/MS analysis. Of the 48 VOCs detected, the toluene concentration exceeded the recommended air quality guidelines in 2% of the outdoor samples, and the benzene concentration exceeded these guidelines in 17.5% and 19.5% of the indoor and outdoor samples, respectively. Industrial and vehicle emissions were negligible. Emissions from oil fields, various crude oil production and flaring activities in the north were major sources of VOCs in the ambient air. The VOC profiles;seasonal, monthly, and weekday/weekend variations;and their effects on ozone formation potentials are discussed. The results indicate that the most abundant class of chemical compounds was oxygenated compounds, of which acetone, acetaldehyde, propanal, methanol, ethanol, and 2-propanol were the most dominant species. Propene and toluene were the most abundant species of aliphatic and aromatic hydrocarbons, respectively.

The Calendar Anomalies of Stock Return in Thailand

This paper aims to examine the existence of calendar anomalies including month-of-year effect, turn-of-month effect, and weekend effect in Thai stock market. The stock return is computed from SET index during 1988 to 2009 and the SET50 index gathered since it was created in 1995. The unit root test is performed to ensure that the stock return series have no unit root. The multiple regression techniques using dummy variables are employed to test the difference of the return during each calendar anomalies period. If the regression model suffers from conditional heteroskedasticity, the GARCH （1, 1） model will be used instead of normal ordinary least square regression. It was found that the calendar anomalies exist in Thai stock market. The return is abnormally high during December and January, which can be addressed to be the turn-of-year effect. The return during the turn-of-month period, which can be defined as the last trading day and the first four trading days of the following months, is also abnormally high. Finally, the return is also abnormally high on Fridays but abnormally low on Mondays, which is addressed as weekend effect. This may create the opportunity to make above-average profit to investors exploiting these calendar anomalies. Although these calendar anomalies may be difficult to be exploited in practice because of transaction costs and ability to replicate the stock index, the existing evidence of calendar anomalies can help investors as the clue for the timing of investment.

Weekend Balle──A look at a purveyor of the fine arts

ＷｅｅｋｅｎｄＢａｌｌｅｔＡｌｏｏｋａｔａｐｕｒｖｅｙｏｒｏｆｔｈｅｆｉｎｅａｒｔｓＡｌｏｏｋａｔａｐｕｒｖｅｙｏｒｏｆｔｈｅｆｉｎｅａｒｔｓＢｙｓｔａｆｆｒｅｐｏｒｔｅｒＺＨＡＮＧＸＵＥＹＩＮＧＩＮａｓｐａｃｉｏｕｓ，ｂｒｉｇｈｔｌｙ－ｌｉｔｃｌａ...

Benelli Weekend 精彩刚刚开始

点燃激情29日早上,雨过天晴。9点17分,本届活动大幕开启。Benelli Weekend潍坊站活动得到了峡山经济开发区的大力支持,区领导坐镇活动现场并在开幕式上发表了热情洋溢的讲话。企业也对活动表示出了足够的重视—钱江摩托股份有限公司副总经理周西平先生、贝纳利公司营销总监张超先生、BK2机车总经理张超先生(同名)等各级领导亲临现场,周西平先生在致辞中表达了公司在服务用户、服务车迷、打造机车文化圈等方面的决心和举措,而钱江与哈雷合作后的首款新车的上市计划则勾起了现场车迷的浓厚兴趣……

After Breaking the Vase

It was the weekend yesterday, so I didn’t have to go to school as usual. Dad was on business and Mom went to the supermarket. I was lonely①at home.“Wow,”I said to myself,“it’s time for me to enjoy the good times today!”So I began to play football at home after finished②my homework. Suddenly, I kicked the ball so hard that it hit a vase and broke it. It was my mom’s favorite. I decided to tell my mom it was the fault of the cat because I was afraid she will③come back and beat me. Two hours later, mom got home. However, on second thought, I told my mom what true④happened. Instead of beating me, Mom said to myself⑤,“Honesty is the most important thing and I hope you can learn to be honest even when no one sees what happens.” I would never make such a foolish mistake.