A whole process damage constitutive model for layered sandstone under uniaxial compression based on Logistic function

Bedding structural planes significantly influence the mechanical properties and stability of engineering rock masses.This study conducts uniaxial compression tests on layered sandstone with various bedding angles(0°,15°,30°,45°,60°,75°and 90°)to explore the impact of bedding angle on the deformational mechanical response,failure mode,and damage evolution processes of rocks.It develops a damage model based on the Logistic equation derived from the modulus’s degradation considering the combined effect of the sandstone bedding dip angle and load.This model is employed to study the damage accumulation state and its evolution within the layered rock mass.This research also introduces a piecewise constitutive model that considers the initial compaction characteristics to simulate the whole deformation process of layered sandstone under uniaxial compression.The results revealed that as the bedding angle increases from 0°to 90°,the uniaxial compressive strength and elastic modulus of layered sandstone significantly decrease,slightly increase,and then decline again.The corresponding failure modes transition from splitting tensile failure to slipping shear failure and back to splitting tensile failure.As indicated by the modulus’s degradation,the damage characteristics can be categorized into four stages:initial no damage,damage initiation,damage acceleration,and damage deceleration termination.The theoretical damage model based on the Logistic equation effectively simulates and predicts the entire damage evolution process.Moreover,the theoretical constitutive model curves closely align with the actual stress−strain curves of layered sandstone under uniaxial compression.The introduced constitutive model is concise,with fewer parameters,a straightforward parameter determination process,and a clear physical interpretation.This study offers valuable insights into the theory of layered rock mechanics and holds implications for ensuring the safety of rock engineering.

A comparison of model choice strategies for logistic regression

Purpose:The purpose of this study is to develop and compare model choice strategies in context of logistic regression.Model choice means the choice of the covariates to be included in the model.Design/methodology/approach:The study is based on Monte Carlo simulations.The methods are compared in terms of three measures of accuracy:specificity and two kinds of sensitivity.A loss function combining sensitivity and specificity is introduced and used for a final comparison.Findings:The choice of method depends on how much the users emphasize sensitivity against specificity.It also depends on the sample size.For a typical logistic regression setting with a moderate sample size and a small to moderate effect size,either BIC,BICc or Lasso seems to be optimal.Research limitations:Numerical simulations cannot cover the whole range of data-generating processes occurring with real-world data.Thus,more simulations are needed.Practical implications:Researchers can refer to these results if they believe that their data-generating process is somewhat similar to some of the scenarios presented in this paper.Alternatively,they could run their own simulations and calculate the loss function.Originality/value:This is a systematic comparison of model choice algorithms and heuristics in context of logistic regression.The distinction between two types of sensitivity and a comparison based on a loss function are methodological novelties.

Enhancing PDF Malware Detection through Logistic Model Trees

Malware is an ever-present and dynamic threat to networks and computer systems in cybersecurity,and because of its complexity and evasiveness,it is challenging to identify using traditional signature-based detection approaches.The study article discusses the growing danger to cybersecurity that malware hidden in PDF files poses,highlighting the shortcomings of conventional detection techniques and the difficulties presented by adversarial methodologies.The article presents a new method that improves PDF virus detection by using document analysis and a Logistic Model Tree.Using a dataset from the Canadian Institute for Cybersecurity,a comparative analysis is carried out with well-known machine learning models,such as Credal Decision Tree,Naïve Bayes,Average One Dependency Estimator,Locally Weighted Learning,and Stochastic Gradient Descent.Beyond traditional structural and JavaScript-centric PDF analysis,the research makes a substantial contribution to the area by boosting precision and resilience in malware detection.The use of Logistic Model Tree,a thorough feature selection approach,and increased focus on PDF file attributes all contribute to the efficiency of PDF virus detection.The paper emphasizes Logistic Model Tree’s critical role in tackling increasing cybersecurity threats and proposes a viable answer to practical issues in the sector.The results reveal that the Logistic Model Tree is superior,with improved accuracy of 97.46%when compared to benchmark models,demonstrating its usefulness in addressing the ever-changing threat landscape.

基于Logistic模型的翻译机器人语义自动校准方法

针对翻译机器人在语义翻译过程中由于翻译误差容易导致翻译结果与原始语言意图不符的问题,提出一种基于Logistic模型的语义自动校准方法。通过语音识别模块将语音信号映射为语义文本,对识别的语义文本进行处理,通过改进的广义线性回归模型(GLR)进行误差检测,并基于Logistic模型对翻译结果进行特征分析,预测流畅度以及准确度,实现语义自动校准。设计了针对翻译机器人语义自动校准的对比实验,实验结果表明,与基于Seq2Seq模型的翻译机器人语义自动校准方法相比,所研究方法语义校准的准确率为98%~100%,BLEU评分为35,语义校准时间为8.5~9.4 s。

Utilization of Logistical Regression to the Modified Sine-Gordon Model in the MST Experiment

In this paper, a logistical regression statistical analysis (LR) is presented for a set of variables used in experimental measurements in reversed field pinch (RFP) machines, commonly known as “slinky mode” (SM), observed to travel around the torus in Madison Symmetric Torus (MST). The LR analysis is used to utilize the modified Sine-Gordon dynamic equation model to predict with high confidence whether the slinky mode will lock or not lock when compared to the experimentally measured motion of the slinky mode. It is observed that under certain conditions, the slinky mode “locks” at or near the intersection of poloidal and/or toroidal gaps in MST. However, locked mode cease to travel around the torus;while unlocked mode keeps traveling without a change in the energy, making it hard to determine an exact set of conditions to predict locking/unlocking behaviour. The significant key model parameters determined by LR analysis are shown to improve the Sine-Gordon model’s ability to determine the locking/unlocking of magnetohydrodyamic (MHD) modes. The LR analysis of measured variables provides high confidence in anticipating locking versus unlocking of slinky mode proven by relational comparisons between simulations and the experimentally measured motion of the slinky mode in MST.

Optimization Analysis of Reverse Logistics Models in Supply Chains from the Perspective of Sustainable Development

With the increasing focus on sustainable development goals,the critical role of reverse logistics in supply chains is becoming more evident.Reverse logistics not only enables resource recovery and reuse but also reduces environmental pollution and enhances economic efficiency.However,existing models face significant challenges related to recovery efficiency,cost control,and supply chain coordination.To address these challenges,this study proposes strategies to improve recovery and reuse efficiency,optimize logistics processes,enhance information sharing and collaboration,and encourage active participation from both businesses and consumers.These measures aim to improve the overall efficiency of reverse logistics and support the achievement of sustainable development goals.

Impulsive Logistic Model for Gray Leaf Spots Caused by Cercospora zeae-maydi

[ Objectlve] Impulsive Logistic Model was used to simulate epidemic process of Gray Leaf Spots caused by C. zeae-maydi. [ Method] The pathogen was inoculated in different maize varieties, and the incidence were observed and recorded. Impulsive Logistic Model was used to simulate the development process of the disease, which was compared with actual incidence. [ Result] Artificial inoculation tests showed that impulsive Logistic Model could reflect time dynamic of C. zeae-maydi. Through derivation, exponential growth phase was from maize seedling emergence to eady July in each year, logistic phase was from early July to late August, terminal phase was from eady September to the end of maize growth stage. [ Conclusion] The derivation result from model was consistent with the development biological laws of C. zeae-maydi.

决策树和Logistic回归模型对体外受精-胚胎移植患者妊娠结局的预测价值比较

目的:比较决策树和Logistic回归模型对体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)患者妊娠结局的预测价值。方法:纳入2021年1月至2022年10月在长治医学院附属和平医院接受IVF-ET的患者350例为研究对象,根据妊娠结局分为妊娠成功组(215例)和妊娠失败组(135例)。收集患者临床资料,建立IVF-ET患者妊娠结局Logistic回归和决策树预测模型,并在是否基于Logistic回归结果条件下建立决策树分析模型(决策树1和决策树2),采用受试者工作特征(receiver operating characteristic,ROC)曲线对模型预测效果进行评价。结果:350例患者中,妊娠成功患者占61.43%,妊娠失败者占38.57%。妊娠失败组年龄≥35岁、不孕年限≥5年、周期次数≥1次、有心理精神障碍的患者比例及HCG日血清孕酮水平均高于妊娠成功组,获卵数≥10枚、受精率≥75%的患者比例及HCG日子宫内膜厚度、优质胚胎数小于妊娠成功组(P<0.05)。多因素Logistic回归分析结果显示,年龄、HCG日血清孕酮水平、优质胚胎数及心理精神障碍均是IVF-ET患者妊娠结局的影响因素(P<0.05)。决策树模型显示,年龄、HCG日血清孕酮水平、优质胚胎数为IVF-ET患者妊娠结局的影响因素。Logistic回归模型曲线下面积(area under curve,AUC)为0.832,预测敏感度、特异度和准确度分别为87.3%、71.4%、83.5%;决策树1的AUC为0.859,预测敏感度、特异度和准确度分别为85.1%、76.8%、85.6%;决策树2的AUC为0.820,预测敏感度、特异度和准确度分别为83.7%、73.2%、82.4%。决策树1的AUC大于决策树2(P<0.05),但与Logistic回归模型的AUC比较差异无统计学意义(P>0.05)。结论:Logistic回归模型和决策树模型对于IVF-ET患者妊娠结局均有一定的预测价值。

基于子宫动脉血流参数的Logistic回归模型在妊娠期高血压患者不良分娩结局的预测价值

目的:探究子宫动脉血流参数的Logistic回归模型在妊娠期高血压(HDP)患者不良分娩结局的预测价值。方法:选取2022年4月至2023年6月在我院接受产前检查的203例HDP患者为研究对象(HDP组),同期纳入100例无流产史的妊娠女性作为对照组。所有孕妇均在孕中期进行子宫动脉血流参数检测。比较HDP组和对照组入院时搏动指数(PI)、阻力指数(RI)、收缩期峰值流速/舒张期流速比值(S/D)。通过Logistic回归分析确定与不良分娩结局相关的独立预测因素。通过受试者操作特征(ROC)曲线分析Logistic模型的预测效能。结果:HDP组PI、RI和S/D值均显著高于对照组(P<0.05)。203例HDP患者中,发生不良妊娠结局的有135例,不良妊娠结局发生率为66.50%。Logistic回归模型显示,PI、RI、S/D比值均为HDP患者不良分娩结局发生的独立危险因素(P<0.05)。基于子宫动脉血流参数构建Logistic回归模型预测不良分娩结局的AUC为0.952,SE为0.324,95%CI为0.913~0.977(P<0.001),敏感度为0.896,特异度为0.956,约登指数0.852。结论:子宫动脉血流参数在预测HDP患者不良分娩结局风险方面具有重要意义,可作为临床风险评估的有效工具。

X线联合超声Logistic模型预测乳腺癌腋窝淋巴结转移的价值分析

目的分析与乳腺癌腋窝淋巴结转移相关的X线和超声征象,构建Logistic回归模型并评估其对术前预测腋窝淋巴结状态的临床价值。方法选取2015年1月至2022年1月高密市人民医院收治的312例原发性乳腺癌患者作为研究对象,根据是否发生腋窝淋巴结转移(ALNM)分为转移组(n=141)与未转移组(n=171)。所有患者均行X线及超声检查,比较未转移组与转移组乳腺浸润性导管癌的X线征象、超声征象,采用多因素Logistic回归分析ALNM的影响因素;绘制ROC曲线分析X线、超神征象及Logistic回归模型预测乳腺癌腋窝淋巴结转移的价值。结果两组X线原发灶长径、皮肤增厚、乳头回缩、淋巴结门和淋巴结密度比较差异有统计学意义(P<0.05),两组象限位置、钙化和边缘毛刺比较差异无统计学意义;两组超声原发灶长径、淋巴结皮髓质分界和淋巴结皮质比较差异有统计学意义(P<0.05),两组原发灶高回声晕、后场回声、血流分级和纵横比比较差异无统计学意义。多因素Logistic回归分析结果显示,X线征象的乳房皮肤增厚征象、超声淋巴结皮质增厚征象是乳腺浸润性导管癌患者发生ALNM的独立危险因素(P<0.05)。ROC曲线分析结果显示,X线乳房皮肤增厚征象和超声征象的淋巴结皮质增厚预测淋巴结转移的AUC分别为0.652(95%CI:0.589~0.714)、0.725(95%CI:0.666~0.784),模型预测ALNM的AUC为0.795(95%CI:0.742~0.848),预测效能较好。结论乳腺癌患者的X线皮肤增厚征象和超声腋窝淋巴结皮质增厚征象与ALNM有关,X线联合超声的Logistic模型可较准确地预测乳腺癌患者的腋窝淋巴结状态。

基于Logistic模型和SPC算法的关键技术识别与预测——以卫星互联网为例

识别关键技术有助于在制定技术和市场战略布局中获得先发优势,对我国经济发展、国家安全具有重要意义。文中提出一种融合生命周期与主路径分析的关键技术识别方法,是对已有的研究理论和方法的重要补充。首先,检索相关领域专利数据并进行技术划分;然后,综合运用Lo-gistic模型和SPC算法构建技术轨道,识别关键技术;接着,使用显性技术优势指数比较主要国家技术竞争态势;最后,结合关键技术与技术竞争态势绘制技术路线图,识别技术热点与前沿预测。以卫星互联网为例,阐述该方法的应用过程。研究结果表明,该方法能够较为准确识别出该领域关键技术,揭示全球技术竞争态势,有效实现技术热点识别和未来技术预测;识别出的卫星互联网关键技术,能够为国家发展政策制定与相关产业布局提供参考。

社会融合视角下农民工城市定居意愿探赜——基于Logistic模型的实证研究

农民工的城市定居意愿影响农民工市民化进程,进而影响我国新型城镇化建设与乡村振兴。文章基于2023年873份农民工问卷,在社会融合视角下,构建二元logistic回归模型对农民工的城市定居意愿影响因素进行研究。实证研究表明,只有58%的农民工具有城市定居意愿。农民工性别、年龄、婚姻状况、教育水平、家庭随迁人口数量、城市迁移时间长短等因素对定居意愿均没有显著影响;参加本地医保、身份认同、经济收入、健康状况、承包地等因素对农民工的城市定居意愿影响较大;社会参与度、闲暇生活、居住证等在一定程度上提升农民工的定居意愿。如何持续提升农民工的城市定居意愿,文章从社会关系融合、经济收入及公共服务均等化等三个方面提出了对策建议。

基于Logistic回归的国际时尚品牌销售渠道选择影响因素分析

为了帮助国际时尚品牌合理、科学地选择销售渠道和制定销售策略,以满足不同地区不同类型消费者的需求,提高品牌市场竞争力。首先依据访谈数据确定分析因子,建立影响国际时尚品牌销售渠道选择的多因素分析理论模型,提出可能影响国际品牌销售渠道选择的消费者偏好分析指标体系,从消费者个人特征、心理偏好、品类偏好以及时尚认知4个维度设计问卷并进行调研。运用SPSS软件对问卷回收数据进行录入,并采用Logistic回归分析数据,从而验证模型假设。通过分析结果可知,以上4个维度下的诸多影响因子均对国际品牌销售渠道的选择产生显著影响,并给出了具体的指导策略。品牌商可以根据研究结果制定对应的销售策略,以有效提高销售渠道利用率,最大化提升品牌销售业绩。

贝叶斯Logistic回归模型在中老年人心脏病影响因素分析中的应用

目的探讨贝叶斯Logistic回归模型在心脏病影响因素分析研究中的应用价值。方法数据资料来自2015年中国健康与养老追踪调查中的525例调查对象。利用OpenBUGS软件分别拟合了贝叶斯随机效应和固定效应的Logistic回归模型,并在两种模型中估计各影响因素与因变量关系的优势比(OR)及95%可信区间(95%CI)。结果贝叶斯随机效应和固定效应的Logistic回归模型分析结果均显示,性别、高血压和糖尿病是心脏病患病率的影响因素。两个模型的收敛效果均较好,参数估计结果也相差较小,但随机效应模型的拟合效果略差于固定效应模型(随机效应模型:DIC=156.6,pD=11.96;固定效应模型:DIC=155.8,pD=7.79)。结论在贝叶斯Logistic回归模型中引入随机效应参数需根据具体情况而定,否则反而可能会降低模型的拟合效果。

基于Logistic模型的差分隐私推荐算法

针对大数据环境下的用户隐私保护问题,提出一种基于Logistic模型的差分隐私推荐算法。首先,改进了差分隐私保护下的系统模型,用户对自身数据进行编码后发送给可信的服务器进行数据加扰处理,可信的服务器迭代处理后再推送给分析服务器进行推荐。系统确保了用户的数据只能被可信的服务器进行搜集整理,不会泄露用户隐私。其次,基于Logistic模型给出了差分隐私推荐算法,该算法将用户的数据作为一个整体进行分析,提高了效率。

基于Logistic回归分析CT增强扫描检查中对比剂外渗的影响因素

目的分析CT增强扫描检查中对比剂外渗的影响因素,为临床预防对比剂外渗提供参考依据。方法回顾性分析郑州市第六人民医院2022年9月至2023年7月收治的104例需进行CT增强扫描检查的受检者临床资料,根据其是否发生对比剂外渗情况,将受试者分为未发生组(85例)、发生组(19例)。分析受试者临床资料,对可疑的影响因素单因素方差分析,筛选出有差异的因素再进行二元Logistic回归分析,总结CT增强扫描检查中对比剂外渗的影响因素。结果对比剂外渗发生组年龄≥60岁、有高血压、糖尿病、恶性肿瘤、碘对比剂浓度>370 mg/ml、注射速率≥3 ml/s、注射人员资历≤2年、有化疗史受试者占比与未发生组占比升高(P<0.05)。二元Logistic分析显示,年龄≥60岁、有高血压、糖尿病、恶性肿瘤、碘对比剂浓度>370 mg/ml、注射速率≥3 ml/s、注射人员资历≤2年、有化疗史是CT增强扫描检查中对比剂外渗的影响因素(OR值=3.165、4.646、7.471、6.398、7.614、5.073、6.392、2.779)(P<0.05)。结论年龄≥60岁、有高血压、糖尿病、恶性肿瘤、碘对比剂浓度>370 mg/mL、注射速率≥3 ml/s、注射人员资历≤2年、有化疗史是CT增强扫描检查中对比剂外渗的影响因素,临床可对有以上临床特征的受试者进行密切关注,并积极开展实施针对性防护措施,以降低CT增强扫描检查中对比剂外渗的发生风险。

基于DCE-MRI表现的logistic回归分析模型在乳腺良恶性病变诊断中的应用

目的 分析基于动态对比增强磁共振成像(DCE-M RI)表现的logistic回归分析模型在乳腺良恶性病变诊断中的应用。方法 回顾性分析2021年1月~2023年10月来我院进行乳腺检查患者161例临床资料。其中良性病变60例、恶性病变101例,分别纳入良性组(n=60)及恶性组(n=101)。分析两组DCE-MRI表现差异,进行单因素分析,利用二元Logistic回归分析构建乳腺良恶性病变诊断模型。采用受试者工作特征(ROC)曲线分析乳腺良恶性病变诊断模型的效能。结果 单因素分析显示,良性组与恶性组TIC曲线、BI-RADS分级、早期强化率、边缘形态及病灶大小比较差异有统计学意义(P<0.05);二元Logistic回归分析结果显示, TIC曲线、BI-RADS分级、早期强化率、边缘形态及病灶大小是乳腺良恶性病变危险征像;构建logistic乳腺癌良恶性病变诊断模型Y=-0.633+0.645TIC曲线+2.112×BI-RADS分级+1.142×早期强化率+1.136×边缘形态+1.136×病灶大小;ROC曲线分析显示该模型诊断效能,AUC为0.944,敏感度为83.33%,特异度为85.15%,提示该模型具有较高的诊断效能。结论 基于乳腺病变早期DCE-MRI表现的logistic诊断模型,能够筛选出对乳腺恶性病变鉴别诊断有意义的特征变量,对乳腺良恶性病变具有较高的诊断效能。

基于多元Logistic模型与解释结构模型的乡村旅游可持续发展路径研究

在全面推进乡村振兴战略背景下,乡村旅游成为助推乡村经济高质量的有效路径。基于广西阳朔县23个景区的1005份问卷数据,采用多元Logistic回归模型和解释结构模型,探讨乡村旅游可持续发展因素及内在逻辑关系。研究发现:①旅游资源多样性、特色民俗文化、交通通达度、投资主体结构、管理者的战略视野和进取态度、国家和地方的政策环境都对乡村旅游的可持续性产生显著影响;②旅游资源的多样性和特色民俗文化是影响乡村旅游可持续发展的深层因素,交通通达度和投资主体结构为中层间接因素,而管理者的战略眼光和进取态度、国家及地方政策环境则是直接影响的表层因素;③乡村旅游的可持续发展是由客观环境因素和主观人为因素共同作用的复杂系统,在动态互动中形成了“旅游资源—发展条件—治理环境—乡村旅游的可持续发展”的传导关系。

Logistic回归模型和XGBoost模型对急性缺血性脑卒中患者发生吞咽障碍的预测价值

目的筛选危险因素构建急性缺血性脑卒中后吞咽障碍风险预测模型,对比XGBoost模型和Logistic回归模型的优劣性。方法选取2022年1-12月新疆医科大学第二附属医院神经内科573例急性缺血性脑卒中患者,按7∶3比例随机分为建模组(n=401)和验证组(n=172)。筛选发生吞咽障碍的危险因素,以单因素分析有统计学意义的变量分别建立Logistic回归模型和XGBoost模型。在验证组数据集上使用十折交叉验证法进行内部验证,采用校准曲线、受试者工作特征曲线(ROC曲线)和决策曲线评价两种模型的预测效能。结果多因素Logistic回归分析结果显示,年龄、NIHSS评分、GCS评分、BI指数、脑干病变、构音障碍、失语症、咽反射(正常)是急性缺血性脑卒中后吞咽障碍的影响因素。XGBoost模型特征重要性排序前8位分别为年龄、BI指数、NIHSS评分、咽反射、TOAST分型、白蛋白、文化程度、营养评分。对比两种模型结果显示,XGBoost模型的准确性、精确度、敏感度、F1分值分别为0.849、0.830、0.754、0.790,表现优于Logistic回归模型。Logistic回归、XGBoost模型预测吞咽障碍的AUC值分别是0.894、0.925,两者AUC值比较,差异无统计学意义(P>0.05)。模型的校准曲线和临床决策曲线均显示XGBoost模型准确度和临床实用价值优于Logistic回归模型。结论XGBoost模型和Logistic回归模型均能有效预测急性缺血性脑卒中后吞咽障碍风险,XGBoost模型表现更优,可为临床早期预防急性缺血性脑卒中吞咽障碍提供参考。

基于多模态超声图像特征的Logistic回归模型预测三阴性乳腺癌病灶肿瘤浸润淋巴细胞表达的临床价值

目的探讨基于多模态超声(包括二维超声、剪切波弹性成像、超声造影及自动乳腺全容积成像)图像特征的Logistic回归模型术前预测三阴性乳腺癌(TNBC)病灶肿瘤浸润淋巴细胞(TILs)表达的临床价值。方法选取经病理证实的TNBC女性患者99例,根据TILs表达水平将其分为TILs低表达组41例(TILs表达水平<20%)和TILs高表达组58例(TILs表达水平≥20%),应用二维超声获取病灶形态、方位、边缘、内部回声、后方回声、钙化等特征,剪切波弹性成像检测病灶剪切波速度(SWV),自动乳腺全容积成像获取病灶有无汇聚征、晕环征、导管改变等特征,超声造影获取起始增强时间、增强强度、增强方向、增强模式、局灶性充盈缺损、周围血管征、增强后病变范围等特征。比较两组多模态超声图像特征的差异;应用多因素Logistic回归分析筛选预测TNBC病灶TILs高表达的独立影响因素,并建立回归模型。绘制受试者工作特征(ROC)曲线分析回归模型预测TNBC病灶TILs高表达的诊断效能。结果TIls高表达组二维超声图像特征形态规则、边缘光整、后方回声增强、内部回声不均匀,以及超声造影图像特征高增强、局灶性充盈缺损占比均高于TIls低表达组,差异均有统计学意义(均P<0.05);两组自动乳腺全容积成像特征及SWV比较差异均无统计学意义。多因素Logistic回归分析显示,形态规则、边缘光整、后方回声增强、高增强及局灶性充盈缺损均为预测TNBC病灶TILs高表达的独立影响因素(OR=6.858、3.824、5.909、1.945、6.522,均P<0.05);建立的回归模型为:Logit(P)=-2.989+1.925×形态规则+1.341×边缘光整+1.776×后方回声增强+0.665×高增强+1.875×局灶性充盈缺损;其预测TNBC病灶TILs高表达的ROC曲线下面积为0.772。结论基于多模态超声图像特征的Logistic回归模型对术前预测TNBC病灶TILs表达有一定的临床价值。