The Weining Beishan area of Ningxia Hui Autonomous Region is located at on the western edge of the Helanshan tectonic belt,which is a tectonic joint among Alxa Block,Ordos Block,and North Qilian orogenic belt.However,...The Weining Beishan area of Ningxia Hui Autonomous Region is located at on the western edge of the Helanshan tectonic belt,which is a tectonic joint among Alxa Block,Ordos Block,and North Qilian orogenic belt.However,the tectonic evolution of this area remains unclear due to the lack of magmatic information.This paper conducted researches on geochronology,geochemistry,and Sr-Nd-Hf isotopes of the diorite porphyrites exposed in the Weining Beishan area.The zircon U-Pb dating yields two ages of 145.0±1.1 and 146.2±1.5 Ma,and the whole-rock geochemical data indicate that the diorite porphyrites are metaluminous to weakly peraluminous and high-K calc-alkaline series.The characteristics of highly initial^(87)Sr/^(86)Sr ratios(0.70816 to 0.71047),negativeε_(Nd)(t)(−8.9 to−8.4),and negativeε_(Hf)(t)(−13.8 to−21.2)indicate that the diorite porphyrites originated from partial melting of the middle-lower ancient crust related to the North China Craton.Combined with the regional geology,we suggested that partial melting was triggered by a tectonic activity of deep faults cutting through the crust under the regional stress transformation from compressing to extension during the Late Jurassic–Early Cretaceous,which is probably related to the westward subduction of the Paleo-Pacific Plate.展开更多
OBJECTIVE:To investigate the protective effect and molecular mechanisms of Weining granule on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced gastric cancer in rats.METHODS:A total of sixty healthy male wistar...OBJECTIVE:To investigate the protective effect and molecular mechanisms of Weining granule on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced gastric cancer in rats.METHODS:A total of sixty healthy male wistar rats were randomly divided into five groups,including control group (CG),gastric cancer model group (MG),low-dose Weining granule treated group (LWT),medium-dose Weining granule treated group (MWT),and high-dose Weining granule treated group (HWT).Except the control group,the other groups were treated with MNNG to establish a rat model of gastric cancer.Low-dose Weining granule treated group,medium-dose Weining granule treated group,and high-dose Weining granule treated group were fed 9.0,18.0 and 36.0 g/kg Weining granule,respectively.Histopathologic and molecular biologic technology were adopted to determine the protective effect of Weining granule on MNNG-induced gastric cancer in rats.The pathological changes of gastrointestinal tissue were observed.Meanwhile,the differential expression of proliferation,apoptosis and angiogenesis markers were determined,including proliferating cell nuclear antigen (PCNA),pokemon,cyclin D1,B-cell lymphoma-2 (Bcl-2),caspase-3,phosphatase and tensin homolog (PTEN) and vascular endothelial growth factor (VEGF).RESULTS.:After the MNNG treated,the pathological changes of stomach tissue were improved noticeably,including the intestinal metaplasia and atypic hyperplasia.The experiment was completed in.58 rats (96.67%).As compared with gastric cancer model group,the general states of rats were improved significantly after treated with different dose Weining granule.Moreover,treatment with different doses of Weining granule could inhibit the protein and mRNA expression of PCNA,pokemon,cyclin D1,Bcl-2,and VEGF,while increase caspase-3 and PTEN (P < 0.01).CONCLUSION:Weining granule could improve gastric cancer by suppressing cell proliferation,promoting tumor cell apoptosis,and inhibiting angiogenesis.展开更多
目的测量上颌前磨牙根管的弯曲度。方法从临床采集需要进行根管治疗的病例,从中随机挑选上颌第一、二前磨牙各50牙。根管治疗过程中RVG数字成像系统采用平行光投照技术拍摄正位插针根尖片(插入#10 K锉)。图像分析软件ImagePro Plus 6.0...目的测量上颌前磨牙根管的弯曲度。方法从临床采集需要进行根管治疗的病例,从中随机挑选上颌第一、二前磨牙各50牙。根管治疗过程中RVG数字成像系统采用平行光投照技术拍摄正位插针根尖片(插入#10 K锉)。图像分析软件ImagePro Plus 6.0测量根管弯曲度(分别用Schneider法和Weine法)。结果 Schneider法测得上颌第一、二前磨牙根管在近远中向弯曲度均值为14.02±7.46°及16.56±8.65°;Weine法为20.90±11.51°及24.83±12.85°,两牙位间差异均无统计学意义(P>0.05);2方法测值间存在高度的相关性(相关系数r=0.95;P=0.000),并基本符合这样的规律:Schneider法测值小于Weine法测值,但大于后者的1/2。结论掌握上颌前磨牙根管弯曲的特点对于根管预备取得成功具有重要的价值。展开更多
It is shown that the measurement of only one component of the Wein’s spectrum of thermal radiation in range λT ≤ 3000 (°C μm) is sufficient to estimate the true temperature and spectral emissivity of the s...It is shown that the measurement of only one component of the Wein’s spectrum of thermal radiation in range λT ≤ 3000 (°C μm) is sufficient to estimate the true temperature and spectral emissivity of the selected component with sufficient accuracy, although more than one hundred years this statement was considered as incorrect. The proposed method is based on the formation of the linear dependence of the logarithm of the emissivity of not real wavelengths and artificially generated “virtual” spectral components.展开更多
文摘The Weining Beishan area of Ningxia Hui Autonomous Region is located at on the western edge of the Helanshan tectonic belt,which is a tectonic joint among Alxa Block,Ordos Block,and North Qilian orogenic belt.However,the tectonic evolution of this area remains unclear due to the lack of magmatic information.This paper conducted researches on geochronology,geochemistry,and Sr-Nd-Hf isotopes of the diorite porphyrites exposed in the Weining Beishan area.The zircon U-Pb dating yields two ages of 145.0±1.1 and 146.2±1.5 Ma,and the whole-rock geochemical data indicate that the diorite porphyrites are metaluminous to weakly peraluminous and high-K calc-alkaline series.The characteristics of highly initial^(87)Sr/^(86)Sr ratios(0.70816 to 0.71047),negativeε_(Nd)(t)(−8.9 to−8.4),and negativeε_(Hf)(t)(−13.8 to−21.2)indicate that the diorite porphyrites originated from partial melting of the middle-lower ancient crust related to the North China Craton.Combined with the regional geology,we suggested that partial melting was triggered by a tectonic activity of deep faults cutting through the crust under the regional stress transformation from compressing to extension during the Late Jurassic–Early Cretaceous,which is probably related to the westward subduction of the Paleo-Pacific Plate.
基金Supported by the National Nature Science Foundation of China(No.81660743)the Project of Guangxi Scholars+1 种基金the Special Project of Guangxi Traditional Chinese Medicine Administration Bureau(No.GZYZ-10-18)the Project of Guangxi Young Teacher Fundamental Ability Promotion(No.2017KY0298)
文摘OBJECTIVE:To investigate the protective effect and molecular mechanisms of Weining granule on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced gastric cancer in rats.METHODS:A total of sixty healthy male wistar rats were randomly divided into five groups,including control group (CG),gastric cancer model group (MG),low-dose Weining granule treated group (LWT),medium-dose Weining granule treated group (MWT),and high-dose Weining granule treated group (HWT).Except the control group,the other groups were treated with MNNG to establish a rat model of gastric cancer.Low-dose Weining granule treated group,medium-dose Weining granule treated group,and high-dose Weining granule treated group were fed 9.0,18.0 and 36.0 g/kg Weining granule,respectively.Histopathologic and molecular biologic technology were adopted to determine the protective effect of Weining granule on MNNG-induced gastric cancer in rats.The pathological changes of gastrointestinal tissue were observed.Meanwhile,the differential expression of proliferation,apoptosis and angiogenesis markers were determined,including proliferating cell nuclear antigen (PCNA),pokemon,cyclin D1,B-cell lymphoma-2 (Bcl-2),caspase-3,phosphatase and tensin homolog (PTEN) and vascular endothelial growth factor (VEGF).RESULTS.:After the MNNG treated,the pathological changes of stomach tissue were improved noticeably,including the intestinal metaplasia and atypic hyperplasia.The experiment was completed in.58 rats (96.67%).As compared with gastric cancer model group,the general states of rats were improved significantly after treated with different dose Weining granule.Moreover,treatment with different doses of Weining granule could inhibit the protein and mRNA expression of PCNA,pokemon,cyclin D1,Bcl-2,and VEGF,while increase caspase-3 and PTEN (P < 0.01).CONCLUSION:Weining granule could improve gastric cancer by suppressing cell proliferation,promoting tumor cell apoptosis,and inhibiting angiogenesis.
文摘目的测量上颌前磨牙根管的弯曲度。方法从临床采集需要进行根管治疗的病例,从中随机挑选上颌第一、二前磨牙各50牙。根管治疗过程中RVG数字成像系统采用平行光投照技术拍摄正位插针根尖片(插入#10 K锉)。图像分析软件ImagePro Plus 6.0测量根管弯曲度(分别用Schneider法和Weine法)。结果 Schneider法测得上颌第一、二前磨牙根管在近远中向弯曲度均值为14.02±7.46°及16.56±8.65°;Weine法为20.90±11.51°及24.83±12.85°,两牙位间差异均无统计学意义(P>0.05);2方法测值间存在高度的相关性(相关系数r=0.95;P=0.000),并基本符合这样的规律:Schneider法测值小于Weine法测值,但大于后者的1/2。结论掌握上颌前磨牙根管弯曲的特点对于根管预备取得成功具有重要的价值。
文摘It is shown that the measurement of only one component of the Wein’s spectrum of thermal radiation in range λT ≤ 3000 (°C μm) is sufficient to estimate the true temperature and spectral emissivity of the selected component with sufficient accuracy, although more than one hundred years this statement was considered as incorrect. The proposed method is based on the formation of the linear dependence of the logarithm of the emissivity of not real wavelengths and artificially generated “virtual” spectral components.