A rat model of middle cerebral artery permanent occlusion was established using the modified Longa method. Successfully established model animals were treated by blood-letting puncture at twelve Jing-Well points of th...A rat model of middle cerebral artery permanent occlusion was established using the modified Longa method. Successfully established model animals were treated by blood-letting puncture at twelve Jing-Well points of the hand, and/or by injecting mannitol into the caudal vein twice daily. Brain tissue was collected at 24, 48 and 72 hours after modeling, and blood was collected through the retinal vein before Evans blue was injected, approximately 1 hour prior to harvesting of brain tissue. Results showed that Evans blue leakage into brain tissue and serum nitric oxide synthase activity were significantly increased in model rats. Treatment with blood-letting punctures at twelve Jing-Well points of the hand and/or injection of mannitol into the caudal vein reduced the amount of Evans blue leakage into the brain tissue and serum nitric oxide synthase activity to varying degrees. There was no significant difference between single treatment and combined treatment. Experimental findings indicate that blood-letting punctures at twelve Jing-Well points of the hand can decrease blood-brain barrier permeability and serum nitric oxide synthase activity in rats following middle cerebral artery occlusion, and its effect is similar to that of mannitol injection alone and Jing-Well points plus mannitol injection.展开更多
Vacuum well point is a new but faint soft ground treatment method. This work focuses on the consolidation behavior of a reconstituted soft clayey specimen under vacuum well point combined with surcharge loading. The l...Vacuum well point is a new but faint soft ground treatment method. This work focuses on the consolidation behavior of a reconstituted soft clayey specimen under vacuum well point combined with surcharge loading. The laboratory test was conducted through a vacuum-surcharge consolidation apparatus, and the vacuum loading scheme was adopted for vacuum pressure application to investigate the vacuum effect on soil consolidation. In the testing process, some key parameters such as vacuum pressure, pore water pressure and settlement deformation were timely recorded. Furthermore, the water content, void ratio and permeability coefficient of samples collected after loading were measured to reflect the consolidation characteristics. By comparing with the membrane system and membraneless system, something different was found for the vacuum well point method. The results indicate that the consolidation behavior of an axisymmetric single vacuum well point is almost identical to the behavior of vacuum preloading combined with prefabricated vertical drain(PVD), except for the distribution of the vacuum pressure along the well drain due to the structure of the vacuum well point. And the vacuum well point method may be useful for the improvement of soft clayey deposit in a certain depth.展开更多
It is known that there is a discrepancy between field data and the results predicted from the previous equations derived by simplifying three-dimensional（3-D） flow into two-dimensions（2-D）.This paper presents a ne...It is known that there is a discrepancy between field data and the results predicted from the previous equations derived by simplifying three-dimensional（3-D） flow into two-dimensions（2-D）.This paper presents a new steady-state productivity equation for horizontal wells in bottom water drive gas reservoirs.Firstly,the fundamental solution to the 3-D steady-state Laplace equation is derived with the philosophy of source and the Green function for a horizontal well located at the center of the laterally infinite gas reservoir.Then,using the fundamental solution and the Simpson integral formula,the average pseudo-pressure equation and the steady-state productivity equation are achieved for the horizontal section.Two case-studies are given in the paper,the results calculated from the newly-derived formula are very close to the numerical simulation performed with the Canadian software CMG and the real production data,indicating that the new formula can be used to predict the steady-state productivity of such horizontal gas wells.展开更多
The tunneling dynamics of superfluid Fermi gas in a triple-well potential in the unitarity regime is investigated in the present paper. The fixed points of the （0,0） mode and the （π, π） mode are given. We find t...The tunneling dynamics of superfluid Fermi gas in a triple-well potential in the unitarity regime is investigated in the present paper. The fixed points of the （0,0） mode and the （π, π） mode are given. We find that the interaction parameter U and the coupling strength k could have an extreme effect on the quantum tunneling dynamics. We also find that, in the zero mode, only Josophson oscillation appears. However, for the mode, the trapping phenomena take place. An irregular oscillation of the particle number in each well could appear by adjusting the scanning period T. It is noted that if the scanning period is less than a critical point T＊, the particle number will come back to the fixed point with small oscillation, while if T 〉 T＊ the particle number cannot come back to the fixed point, but with irregular oscillations. The dependence of the critical point T＊ on the system parameter of coupling strength k is numerically given.展开更多
By extending the concept of asymptotic weakly Pareto-Nash equilibrium point to vector-valued case, Tikhonov well-posedness and Hadamard well-posedness results of the multiobjective generalized games are established in...By extending the concept of asymptotic weakly Pareto-Nash equilibrium point to vector-valued case, Tikhonov well-posedness and Hadamard well-posedness results of the multiobjective generalized games are established in this paper.展开更多
基金sponsored by the Open Research Fund of Zhejiang First-foremost Key Subject-Acupuncture & Moxibustion,No. ZTK2010A07
文摘A rat model of middle cerebral artery permanent occlusion was established using the modified Longa method. Successfully established model animals were treated by blood-letting puncture at twelve Jing-Well points of the hand, and/or by injecting mannitol into the caudal vein twice daily. Brain tissue was collected at 24, 48 and 72 hours after modeling, and blood was collected through the retinal vein before Evans blue was injected, approximately 1 hour prior to harvesting of brain tissue. Results showed that Evans blue leakage into brain tissue and serum nitric oxide synthase activity were significantly increased in model rats. Treatment with blood-letting punctures at twelve Jing-Well points of the hand and/or injection of mannitol into the caudal vein reduced the amount of Evans blue leakage into the brain tissue and serum nitric oxide synthase activity to varying degrees. There was no significant difference between single treatment and combined treatment. Experimental findings indicate that blood-letting punctures at twelve Jing-Well points of the hand can decrease blood-brain barrier permeability and serum nitric oxide synthase activity in rats following middle cerebral artery occlusion, and its effect is similar to that of mannitol injection alone and Jing-Well points plus mannitol injection.
基金Projects(41202220,41472278)supported by the National Natural Science Foundation of ChinaProject(20120022120003)supported by the Research Fund for the Doctoral Program of Higher Education,ChinaProject(2652012065)supported by the Fundamental Research Funds for Central Universities,China
文摘Vacuum well point is a new but faint soft ground treatment method. This work focuses on the consolidation behavior of a reconstituted soft clayey specimen under vacuum well point combined with surcharge loading. The laboratory test was conducted through a vacuum-surcharge consolidation apparatus, and the vacuum loading scheme was adopted for vacuum pressure application to investigate the vacuum effect on soil consolidation. In the testing process, some key parameters such as vacuum pressure, pore water pressure and settlement deformation were timely recorded. Furthermore, the water content, void ratio and permeability coefficient of samples collected after loading were measured to reflect the consolidation characteristics. By comparing with the membrane system and membraneless system, something different was found for the vacuum well point method. The results indicate that the consolidation behavior of an axisymmetric single vacuum well point is almost identical to the behavior of vacuum preloading combined with prefabricated vertical drain(PVD), except for the distribution of the vacuum pressure along the well drain due to the structure of the vacuum well point. And the vacuum well point method may be useful for the improvement of soft clayey deposit in a certain depth.
基金financial support from the Open Fund(PLN1003) of State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation(Southwest Petroleum University)the National Science and Technology Major Project in the l lth Five-Year Plan(Grant No.2008ZX05054)
文摘It is known that there is a discrepancy between field data and the results predicted from the previous equations derived by simplifying three-dimensional（3-D） flow into two-dimensions（2-D）.This paper presents a new steady-state productivity equation for horizontal wells in bottom water drive gas reservoirs.Firstly,the fundamental solution to the 3-D steady-state Laplace equation is derived with the philosophy of source and the Green function for a horizontal well located at the center of the laterally infinite gas reservoir.Then,using the fundamental solution and the Simpson integral formula,the average pseudo-pressure equation and the steady-state productivity equation are achieved for the horizontal section.Two case-studies are given in the paper,the results calculated from the newly-derived formula are very close to the numerical simulation performed with the Canadian software CMG and the real production data,indicating that the new formula can be used to predict the steady-state productivity of such horizontal gas wells.
基金supported by the National Fundamental Research Program of China(Grant Nos.2007CB814800 and 2011CB921503)the National Natural Science Foundation of China(Grant Nos.11275156,91021021,and 10875098)the Natural Science Foundation of Northwest Normal University(Grant No.NWNU-KJCXGC-03-48)
文摘The tunneling dynamics of superfluid Fermi gas in a triple-well potential in the unitarity regime is investigated in the present paper. The fixed points of the （0,0） mode and the （π, π） mode are given. We find that the interaction parameter U and the coupling strength k could have an extreme effect on the quantum tunneling dynamics. We also find that, in the zero mode, only Josophson oscillation appears. However, for the mode, the trapping phenomena take place. An irregular oscillation of the particle number in each well could appear by adjusting the scanning period T. It is noted that if the scanning period is less than a critical point T＊, the particle number will come back to the fixed point with small oscillation, while if T 〉 T＊ the particle number cannot come back to the fixed point, but with irregular oscillations. The dependence of the critical point T＊ on the system parameter of coupling strength k is numerically given.
基金Supported by Natural Science Foundation of Guizhou Province
文摘By extending the concept of asymptotic weakly Pareto-Nash equilibrium point to vector-valued case, Tikhonov well-posedness and Hadamard well-posedness results of the multiobjective generalized games are established in this paper.
