A feedforword neural network of multi-layer topologies for systems with hysteretic nonlinearity is constructed based on Bouce Wen differential model. It not only reflects the hysteresis force characteristics of the Bo...A feedforword neural network of multi-layer topologies for systems with hysteretic nonlinearity is constructed based on Bouce Wen differential model. It not only reflects the hysteresis force characteristics of the Bouce Wen model, but also determines its corresponding parameters. The simulation results show that restoring forceedisplacement curve hysteresis loop is very close to the real curve. The model trained can accurately predict the time response of system. The model is checked under the noise level. The result shows that the model has higher modeling precision, good generalization capability and a certain anti-interference ability.展开更多
As the first works of Chinese grammar, "Ma Shi Wen Tong" has epoch-making significance in the history of Chinese grammar. It marks that Chinese grammar study has become an independent science. This research ...As the first works of Chinese grammar, "Ma Shi Wen Tong" has epoch-making significance in the history of Chinese grammar. It marks that Chinese grammar study has become an independent science. This research intends to generalize "Wen Tong".展开更多
Ghrelin, a brain-gut peptide that induces anxiety and other abnormal emotions, contributes to the effects of insomnia on emotional behavior. In contrast, the traditional Chinese Medi- cine remedy Wen Dan Tang reduces ...Ghrelin, a brain-gut peptide that induces anxiety and other abnormal emotions, contributes to the effects of insomnia on emotional behavior. In contrast, the traditional Chinese Medi- cine remedy Wen Dan Tang reduces insomnia-related anxiety, which may perhaps correspond to changes in the brain-gut axis. This suggests a possible relationship between Wen Dan Tan^s pharmacological mechanism and the brain-gut axis. Based on this hypothesis, a sleep-deprived rat model was induced and Wen Dan Tang was administered using oral gavage during model es- tablishment. Wen Dan Tang significantly reduced insomnia-related anxiety and prevented Ghrelin level decreases following sleep deprivation, especially in the hypothalamus. Increased expression of Ghrelin receptor mRNA in the hypothalamus was also observed, suggesting that reduced anxi- ety may be a result of Wen Dan Tan＇s regulation of Ghrelin-Ghrelin receptors.展开更多
Objective To observe the characteristics of gene methylation in obese rats with phlegm-dampness syndrome induced by the high-fat diet, and to study the effect of Wen Dan Decoction on gene methylation after the interve...Objective To observe the characteristics of gene methylation in obese rats with phlegm-dampness syndrome induced by the high-fat diet, and to study the effect of Wen Dan Decoction on gene methylation after the intervention. Methods Methylation sites of genes were detected by the MeDIP-seq method. Bioinformatics method was used to analyze the gene methylation characteristics of obesity with phlegmdampness syndrome and the effect of Wen Dan Decoction. Results (1) There were 3 242 methylation differential loci in dietinduced obesity with phlegm-dampness syndrome, of which 1 243 were down-regulated and 1 999 were up-regulated, involving 1 579 differential genes. GO analysis showed that "offactory receptor activity" and others were enriched. The possible signal pathways involved were "Olfactory transduction""Tuberculosis""Systemic lupus erythematosus" and "Ribosome".(2) After the intervention of Wen Dan Decoction in obesity with phlegmdampness syndrome, 4 046 different methylation loci were obtained, including 1 067 down-regulated loci and 2 979 up-regulated loci, involving 2 068 genes. GO analysis showed that "offactory receptor activity" and others were enriched. These genes involved seven signaling pathways, such as "Metabolic pathways".(3) Between diet-induced obesity with phlegm-dampness syndrome and Wen Dan Decoction intervening obesity with the phlegm-dampness syndrome, 582 common genes of methylation differential genes were obtained. After the intervention of Wen Dan Decoction, the number of GO enrichment items was more than that of obesity with phlegm-dampness syndrome, and even the same GO enrichment items involved more genes. Conclusions The phlegm-dampness syndrome of obesityinduced by diet had the characteristics of gene methylation changes, and the intervention of Wen Dan Decoction could also affect the status of gene methylation. The genes affected by Wen Dan Decoction were closely related to the methylation gene of phlegm-dampness syndrome of obesity-induced by diet but covered a wider range.展开更多
On July 4, 2006, an earthquake of MS5.1 took place in Wen’an, Hebei Province, just at the south center of China’s Capital Circle area digital seismograph network. It is the strongest event recorded ever since the ne...On July 4, 2006, an earthquake of MS5.1 took place in Wen’an, Hebei Province, just at the south center of China’s Capital Circle area digital seismograph network. It is the strongest event recorded ever since the network went into operation in 2002. We processed the vast amounts of phase data yielded by the 107 digital seismic stations between 2002~2007 using Wadati method. In order to improve the precision and stability of shear and compressional wave velocities (vP/vS) calculation, we impose a number of restrictions on the computation environment and condition, e.g., the earthquakes are densely concentrated, selected stations are limited in range, the number of stations in- volved in the computation is larger than 5 and linear fitting features high precision and small error. Under these restrictions, the study shows that vP/vS in and around Wen’an and Tangshan underwent a normal-low-normal proc- ess one year before Wen’an earthquake, vP/vS became obviously low and the low ratio lasted for about one year, meanwhile, little variation of vP/vS was seen in Xingtai, northwest of Beijing, southwest of Beijing, Beijing-Tianjin and Beijing; after the quake, the vP/vS returned normal in Wen’an and Tangshan. Error and stability analysis of the calculated result for vP/vS shows it is convincible that anomaly appeared in and around Wen’an and Tangshan be- fore Wen’an earthquake.展开更多
There are three different opinions of the first sentence from Qin Nang Ao Yu (青囊奥语), which was written by Yang Jun-song (杨筠松). They are “Kun Ren Yi (坤壬乙) should start from the star Ju Men (巨门)”;“Kun Ren...There are three different opinions of the first sentence from Qin Nang Ao Yu (青囊奥语), which was written by Yang Jun-song (杨筠松). They are “Kun Ren Yi (坤壬乙) should start from the star Ju Men (巨门)”;“Kun Ren Yi should start from the star Wen Qu (文曲)” and “Kun Ren Yi should start from both the star Lian Zhen and the star Ju Men (Lian Ju (廉巨))”. Because of the sectarianism,though the people were at odds with the opinions, we cannot find out any comprehensive and objective study on these. According to the analysis of some relevant literatures, it can be seen that there are two viewpoints nowadays. One of the viewpoints deemed that the first sentence was falsified by Jiang Da-hong (蒋大鸿), and another one deemed that was falsified by Zhang Shou-qi (张受祺). But neither of the view was credible. More precisely is that “Wen Qu” and “Ju Men” were both found in the publications simultaneously, and there were more “Wen Qu”, during the period of the end of the Ming Dynasty and the era of the emperors Kangxi and Qianlong of the Qing Dynasty. The influence of “Ju Meg” was gradually spread when Jiang Da-hong used it in his book and also Si Ku Quan Shu (四库全书) cited it, then let to more pithy formulas of “Ju Men” to be used now. And the “Lian Ju” was rare to be used except Duan Mu Guo-hu (端木国瑚) who used to use it. The way of interpretation is so multiple and complex on the “Wen Qu” and “Ju Men” from the Qin Nang Ao Yu, according to the perspective of Feng Shui, which is reflecting the pluralism and uncertainty of the interpretation of the traditional Feng Shui. And it is still need to be required a further more careful consideration on how to treat the studies of the traditional Feng Shui for the nowadays scholars.展开更多
Based on the difficulties of polysemy in translation,this paper explains the rationality of prototype category theory in polysemy translation.Taking Li Zhaoguo’s English version of Su Wen as the research object,it an...Based on the difficulties of polysemy in translation,this paper explains the rationality of prototype category theory in polysemy translation.Taking Li Zhaoguo’s English version of Su Wen as the research object,it analyzes the polysemy translation of“Jing”,“Zong”,and“Jiu”as examples,and puts forward the translation strategies of polysemy under the guidance of prototype category theory:equivalent substitution between categories,synonymous conversion between categories,transliteration and introspection outside categories,so as to provide reference for the study of polysemy in English translation of texts on traditional Chinese medicine.展开更多
文摘A feedforword neural network of multi-layer topologies for systems with hysteretic nonlinearity is constructed based on Bouce Wen differential model. It not only reflects the hysteresis force characteristics of the Bouce Wen model, but also determines its corresponding parameters. The simulation results show that restoring forceedisplacement curve hysteresis loop is very close to the real curve. The model trained can accurately predict the time response of system. The model is checked under the noise level. The result shows that the model has higher modeling precision, good generalization capability and a certain anti-interference ability.
文摘As the first works of Chinese grammar, "Ma Shi Wen Tong" has epoch-making significance in the history of Chinese grammar. It marks that Chinese grammar study has become an independent science. This research intends to generalize "Wen Tong".
基金supported by the National Natural Science Youth Foundation in China,No.81001501the Natural Science Foundation of Beijing in China,No.7112071Beijing University of Chinese Medicine Key Project–Nautical Chinese Medicine in China,No.522/100604054
文摘Ghrelin, a brain-gut peptide that induces anxiety and other abnormal emotions, contributes to the effects of insomnia on emotional behavior. In contrast, the traditional Chinese Medi- cine remedy Wen Dan Tang reduces insomnia-related anxiety, which may perhaps correspond to changes in the brain-gut axis. This suggests a possible relationship between Wen Dan Tan^s pharmacological mechanism and the brain-gut axis. Based on this hypothesis, a sleep-deprived rat model was induced and Wen Dan Tang was administered using oral gavage during model es- tablishment. Wen Dan Tang significantly reduced insomnia-related anxiety and prevented Ghrelin level decreases following sleep deprivation, especially in the hypothalamus. Increased expression of Ghrelin receptor mRNA in the hypothalamus was also observed, suggesting that reduced anxi- ety may be a result of Wen Dan Tan＇s regulation of Ghrelin-Ghrelin receptors.
基金the funding support from the National Natural Science Youth Foundation of China: Effect of Wen Dan Decoction on gene promoter methylations related to fat metabolism (No. 81302907)
文摘Objective To observe the characteristics of gene methylation in obese rats with phlegm-dampness syndrome induced by the high-fat diet, and to study the effect of Wen Dan Decoction on gene methylation after the intervention. Methods Methylation sites of genes were detected by the MeDIP-seq method. Bioinformatics method was used to analyze the gene methylation characteristics of obesity with phlegmdampness syndrome and the effect of Wen Dan Decoction. Results (1) There were 3 242 methylation differential loci in dietinduced obesity with phlegm-dampness syndrome, of which 1 243 were down-regulated and 1 999 were up-regulated, involving 1 579 differential genes. GO analysis showed that "offactory receptor activity" and others were enriched. The possible signal pathways involved were "Olfactory transduction""Tuberculosis""Systemic lupus erythematosus" and "Ribosome".(2) After the intervention of Wen Dan Decoction in obesity with phlegmdampness syndrome, 4 046 different methylation loci were obtained, including 1 067 down-regulated loci and 2 979 up-regulated loci, involving 2 068 genes. GO analysis showed that "offactory receptor activity" and others were enriched. These genes involved seven signaling pathways, such as "Metabolic pathways".(3) Between diet-induced obesity with phlegm-dampness syndrome and Wen Dan Decoction intervening obesity with the phlegm-dampness syndrome, 582 common genes of methylation differential genes were obtained. After the intervention of Wen Dan Decoction, the number of GO enrichment items was more than that of obesity with phlegm-dampness syndrome, and even the same GO enrichment items involved more genes. Conclusions The phlegm-dampness syndrome of obesityinduced by diet had the characteristics of gene methylation changes, and the intervention of Wen Dan Decoction could also affect the status of gene methylation. The genes affected by Wen Dan Decoction were closely related to the methylation gene of phlegm-dampness syndrome of obesity-induced by diet but covered a wider range.
基金Special Fund for Basic Scientific Research, IGPCEA (DQJB06B03)National Program for Key Science and Technology Projects during the 11th Five-year Plan Period (2006BAC01B03-04-04)Contribution No.08FE3004, Institute of Geophysics, China Earthquake Administration.
文摘On July 4, 2006, an earthquake of MS5.1 took place in Wen’an, Hebei Province, just at the south center of China’s Capital Circle area digital seismograph network. It is the strongest event recorded ever since the network went into operation in 2002. We processed the vast amounts of phase data yielded by the 107 digital seismic stations between 2002~2007 using Wadati method. In order to improve the precision and stability of shear and compressional wave velocities (vP/vS) calculation, we impose a number of restrictions on the computation environment and condition, e.g., the earthquakes are densely concentrated, selected stations are limited in range, the number of stations in- volved in the computation is larger than 5 and linear fitting features high precision and small error. Under these restrictions, the study shows that vP/vS in and around Wen’an and Tangshan underwent a normal-low-normal proc- ess one year before Wen’an earthquake, vP/vS became obviously low and the low ratio lasted for about one year, meanwhile, little variation of vP/vS was seen in Xingtai, northwest of Beijing, southwest of Beijing, Beijing-Tianjin and Beijing; after the quake, the vP/vS returned normal in Wen’an and Tangshan. Error and stability analysis of the calculated result for vP/vS shows it is convincible that anomaly appeared in and around Wen’an and Tangshan be- fore Wen’an earthquake.
文摘There are three different opinions of the first sentence from Qin Nang Ao Yu (青囊奥语), which was written by Yang Jun-song (杨筠松). They are “Kun Ren Yi (坤壬乙) should start from the star Ju Men (巨门)”;“Kun Ren Yi should start from the star Wen Qu (文曲)” and “Kun Ren Yi should start from both the star Lian Zhen and the star Ju Men (Lian Ju (廉巨))”. Because of the sectarianism,though the people were at odds with the opinions, we cannot find out any comprehensive and objective study on these. According to the analysis of some relevant literatures, it can be seen that there are two viewpoints nowadays. One of the viewpoints deemed that the first sentence was falsified by Jiang Da-hong (蒋大鸿), and another one deemed that was falsified by Zhang Shou-qi (张受祺). But neither of the view was credible. More precisely is that “Wen Qu” and “Ju Men” were both found in the publications simultaneously, and there were more “Wen Qu”, during the period of the end of the Ming Dynasty and the era of the emperors Kangxi and Qianlong of the Qing Dynasty. The influence of “Ju Meg” was gradually spread when Jiang Da-hong used it in his book and also Si Ku Quan Shu (四库全书) cited it, then let to more pithy formulas of “Ju Men” to be used now. And the “Lian Ju” was rare to be used except Duan Mu Guo-hu (端木国瑚) who used to use it. The way of interpretation is so multiple and complex on the “Wen Qu” and “Ju Men” from the Qin Nang Ao Yu, according to the perspective of Feng Shui, which is reflecting the pluralism and uncertainty of the interpretation of the traditional Feng Shui. And it is still need to be required a further more careful consideration on how to treat the studies of the traditional Feng Shui for the nowadays scholars.
文摘Based on the difficulties of polysemy in translation,this paper explains the rationality of prototype category theory in polysemy translation.Taking Li Zhaoguo’s English version of Su Wen as the research object,it analyzes the polysemy translation of“Jing”,“Zong”,and“Jiu”as examples,and puts forward the translation strategies of polysemy under the guidance of prototype category theory:equivalent substitution between categories,synonymous conversion between categories,transliteration and introspection outside categories,so as to provide reference for the study of polysemy in English translation of texts on traditional Chinese medicine.
