This paper introduces China English and China English lexis,and analyzes the four ways of the word-formation of China English lexis:transliteration,loan translation,loan-blend and coinage.The analysis can show that Ch...This paper introduces China English and China English lexis,and analyzes the four ways of the word-formation of China English lexis:transliteration,loan translation,loan-blend and coinage.The analysis can show that China English is used to express the language system in a special situation in China,and it has brought large number of new lexis and new vision into world Englishes,which has enhanced the expressive force of English.展开更多
Chinese noun-classifier compound words show different properties in lexical meaning and syntactic collocation. The complexity of these compounds lies in the grammaticalization of classifiers’ system. Some nouns used...Chinese noun-classifier compound words show different properties in lexical meaning and syntactic collocation. The complexity of these compounds lies in the grammaticalization of classifiers’ system. Some nouns used as classifiers in the position of classifier are not grammaticalized into real classifiers which are temporary classifiers. So some of them are real noun-classifier compounds and some belong to noun-noun compounds. This paper attempts to analyze the structural relation between noun morpheme and classifier morpheme within the word. It also explains that the noun and the classifier compound in the position of light noun in the nP structure.展开更多
In Chinese, compound words denoting kinship axe frequently used. This paper classifies such words into two categories: coordinative and non-coordinative. Each type has subcategories. Under the framework of Distribute...In Chinese, compound words denoting kinship axe frequently used. This paper classifies such words into two categories: coordinative and non-coordinative. Each type has subcategories. Under the framework of Distributed Morphology, this paper focuses on the coordinative compound words. They consist of two roots which finally form a NP with the category-giving morpheme. Besides, there are some idioms and infrequent uses which can be explained in the Encyclopedia.展开更多
A great deal of new words are emerging and coming into vogue.Most of the previous studies on Chinese new words focused on their classification,form and meaning,as well as the social motivations.This thesis chooses to ...A great deal of new words are emerging and coming into vogue.Most of the previous studies on Chinese new words focused on their classification,form and meaning,as well as the social motivations.This thesis chooses to study the concept metaphor of Chinese new metaphorical compounds from the cognitive perspective based on 396 new words in 2010 and aims to classify the new metaphorical words in a new way and pay attention to the analysis of word formation of new metaphorical compounds.Besides,this paper attempts to explore the understanding process of metaphorical new words.展开更多
In English learning most students have difficulty memorizing words and reciting words has become a nation-wide problem for most English learners. This paper introduces a way of word-formation - conversion to help lang...In English learning most students have difficulty memorizing words and reciting words has become a nation-wide problem for most English learners. This paper introduces a way of word-formation - conversion to help language learners enlarge their vocabulary efficiently.展开更多
It is important to predict the fracture distribution in the tight reservoirs of the Ordos Basin because fracturing is very crucial for the reconstruction of the low-permeability reservoirs. Three-dimensional finite el...It is important to predict the fracture distribution in the tight reservoirs of the Ordos Basin because fracturing is very crucial for the reconstruction of the low-permeability reservoirs. Three-dimensional finite element models are used to predict the fracture orientation and distribution of the Triassic Yanchang Formation in the Longdong area, southern Ordos Basin. The numerical modeling is based on the distribution of sand bodies in the Chang 7a and 72 members, and the different forces that have been exerted along each boundary of the basin in the Late Mesozoic and the Cenozoic. The calculated results demonstrate that the fracture orientations in the Late Mesozoic and the Ceno- zoic are NW-EW and NNE-ENE, respectively. In this paper, the two-factor method is applied to analyze the distribution of fracture density. The distribution maps of predicted fracture density in the Chang 71 and 72 members are obtained, indicating that the tectonic movement in the Late Mesozoic has a greater influence on the fracture development than that in the Cenozoic. The average fracture densities in the Chang 71 and 72 members are similar, but there are differences in their distributions. Compared with other geological elements, the lithology and the layer thickness are the primary factors that control the stress distribution in the study area, which further determine the fracture distribution in the stable Ordos Basin. The predicted fracture density and the two-factor method can be utilized to guide future exploration in the tight-sand reservoirs.展开更多
Background:miRNAs are closely related to bone metabolism.Studies have shown that Erxian decoction can improve bone metabolism,possibly achieving this regulatory effect through miRNA targets.Netinfer was used to predic...Background:miRNAs are closely related to bone metabolism.Studies have shown that Erxian decoction can improve bone metabolism,possibly achieving this regulatory effect through miRNA targets.Netinfer was used to predict the miRNA targets of Erxian decoction for the treatment of postmenopausal osteoporosis,and the results were validated by clinical trials.Methods:In this study,we identified possible targets of Erxian decoction in osteoporosis by means of network pharmacological analysis and bioinformatic prediction.Fifteen cases of postmenopausal osteoporosis with kidney Yin and Yang deficiency(In traditional Chinese medicine,kidney Yin nourishes and moistens the tissues of the internal organs of the body,while kidney Yang promotes and warms the tissues of the internal organs of the body.)were treated with Erxian decoction for four weeks,and serum bone metabolism indices(P1NP,osteocalcin,andβ-CTX)and miRNA-335-5p expression were measured before and after treatment.Results:The constructed miRNA postmenopausal osteoporosis related gene network of the effective compound of the Erxian decoction has 296 points and 981 edges.The 39 postmenopausal osteoporosis related genes regulated by miRNA-335-5p were enriched in ossification,while the signaling pathways were enriched in rheumatoid arthritis,the Toll signaling pathway,the HIF-1 signaling pathway,and the MAPK signaling pathway.After taking Erxian decoction,the expression of the serum bone formation index(P1NP,osteocalcin)and miRNA-335-5p gene expression levels increased significantly.The alterations in P1NP and osteocalcin were correlated with the changes in miRNA-335-5p.Conclusion:Circulating miRNA-335-5p may serve as an important target of Erxian decoction in the treatment of postmenopausal women.The effect of Erxian decoction on bone formation is significant,but the underlying mechanism requires further investigation.展开更多
Sandstones attributed to different lacustrine sediment gravity flows are present in the 7th and 6th members of the Yanchang Formation in the Ordos Basin, China. These differences in their origins led to different sand...Sandstones attributed to different lacustrine sediment gravity flows are present in the 7th and 6th members of the Yanchang Formation in the Ordos Basin, China. These differences in their origins led to different sandstone distributions which control the scale and connectivity of oil and gas reservoirs. Numerous cores and outcrops were analysed to understand the origins of these sandstones. The main origin of these sandstones was analysed by statistical methods, and well logging data were used to study their vertical and horizontal distributions. Results show that the sandstones in the study area accu- mulated via sandy debris flows, turbidity currents and slumping, and sandy debris flows predominate. The sand- stone associated with a single event is characteristically small in scale and exhibits poor lateral continuity. How- ever, as a result of multiple events that stacked gravity flow-related sandstones atop one another, sandstones are extensive overall, as illustrated in the cross section and isopach maps. Finally, a depositional model was developed in which sandy debris flows predominated and various other types of small-scale gravity flows occurred frequently, resulting in extensive deposition of sand bodies across a large area.展开更多
Mechanical stimuli play an essential role in maintaining bone remodeling and skeletal integrity.Meanwhile,bone can respond to the changes of mechanical condition to adjust its mass and architecture.Clinical studies di...Mechanical stimuli play an essential role in maintaining bone remodeling and skeletal integrity.Meanwhile,bone can respond to the changes of mechanical condition to adjust its mass and architecture.Clinical studies discover that bedridden patients showed osteoporotic T-scores and low bone mineral density,and long-term immobilized patients presented reduced markers of bone formation.However,as bone formation mediated by osteoblast differentiation is a complex process,the underlying molecular mechanism of mechanical stimuli regulating bone formation is still unclear.Recent evidences show that microRNAs(miRNAs)are involved in mechanical stimuli regulating bone formation or osteoblast differentiation.Nevertheless,no direct evidence identifies mechanoresponsive miRNA in both human and animal bones,and clarifies its mechanoresponsive role under different mechanical conditions(e.g.mechanical unloading,reloading,loading).In the current study,we screened for differentially expressed miRNAs in bone specimens of bedridden patients with fractures,then identified that the expression of miR-138-5p,but not the other miRNAs,altered withbedridden time and was negatively correlated with the expression of the bone formation marker genes Alp(alkaline phosphatase).Moreover,miR-138-5p was up-regulated with reduced bone formation during unloading and down-regulated with increased bone formation during reloading in hind4imb unloaded mice.In addition,miR-138-5p was verified to be responsive to different mechanical unloading condition and cyclic mechanical stretch condition in primary osteogenic cells,respectively.Further in vitro data suggested that mechanoresponsive miR-138-5p directly targeted microtubule actin crosslinking factor 1(MACF1)to inhibit osteoblast differentiation.In vivo,we constructed an osteoblastic miR-138-5p transgenic mice model(TG138)with the Runx2promoter,and found that overexpression miR-138-5p supressed bone formation.Moreover,osteoblast-targeted inhibition of miR-138-5p sensitized bone anabolic response to mechanical loading in TG138 mice.Predominantly,the osteoblast-targeted inhibition of miR-138-5p could counteract bone formation reduction induced by hind limb unloading.Taken together,the mechanoresponsive miR-138-5p inhibited bone anabolic response for developing a novel bone anabolic sensitization strategy.展开更多
This paper considers nonlinear dynamics of teth- ered three-body formation system with their centre of mass staying on a circular orbit around the Earth, and applies the theory of space manifold dynamics to deal with ...This paper considers nonlinear dynamics of teth- ered three-body formation system with their centre of mass staying on a circular orbit around the Earth, and applies the theory of space manifold dynamics to deal with the nonlinear dynamical behaviors of the equilibrium configurations of the system. Compared with the classical circular restricted three body system, sixteen equilibrium configurations are obtained globally from the geometry of pseudo-potential energy sur- face, four of which were omitted in the previous research. The periodic Lyapunov orbits and their invariant manifolds near the hyperbolic equilibria are presented, and an iteration procedure for identifying Lyapunov orbit is proposed based on the differential correction algorithm. The non-transversal intersections between invariant manifolds are addressed to generate homoclinic and heteroclinic trajectories between the Lyapunov orbits. (3,3)- and (2,1)-heteroclinic trajecto- ries from the neighborhood of one collinear equilibrium to that of another one, and (3,6)- and (2,1)-homoclinic trajecto- ries from and to the neighborhood of the same equilibrium, are obtained based on the Poincar6 mapping technique.展开更多
With the deveolpment of the society. and culture, English vocabulary changerapidly. New words enter the English language daily at an ever -- inereasing rate. Greatchange in vocabulary, however, does not cause great ch...With the deveolpment of the society. and culture, English vocabulary changerapidly. New words enter the English language daily at an ever -- inereasing rate. Greatchange in vocabulary, however, does not cause great change in the rules of English word for-mation. This paper will take some new words as example to show the treat importance of thetraditional principles in the formation of new words, though there are slight changes in themtoo.展开更多
The observation of oxygen(O)-and nitrogen(N)-bearing molecules gives an idea about the complex prebiotic chemistry in the interstellar medium.Recent millimeter and submillimeter wavelength observations have shown the ...The observation of oxygen(O)-and nitrogen(N)-bearing molecules gives an idea about the complex prebiotic chemistry in the interstellar medium.Recent millimeter and submillimeter wavelength observations have shown the presence of complex O-and N-bearing molecules in the star formation regions.So,the investigation of those molecules is crucial to understanding the chemical complexity in the star-forming regions.In this article,we present the identification of the rotational emission lines of N-bearing molecules ethyl cyanide(C_(2)H_(5)CN)and cyanoacetylene(HC_(3)N),and O-bearing molecule methyl formate(CH_(3)OCHO)toward high-mass protostar IRAS18089–1732 using the Atacama Compact Array.We also detected the emission lines of both the N-and O-bearing molecule formamide(NH_(2)CHO)in the envelope of IRAS 18089–1732.We have detected the v=0 and 1 state rotational emission lines of CH_(3)OCHO.We also detected the two vibrationally excited states of HC_(3)N(v7=1 and v7=2).The estimated fractional abundances of C_(2)H_(5)CN,HC_(3)N(v7=1),HC_(3)N(v7=2),and NH_(2)CHO toward IRAS 18089–1732 are(1.40±0.5)×10^(-10),(7.5±0.7)×10^(-11),(3.1±0.4)×10^(-11),and(6.25±0.82)×10^(-11)respectively.Similarly,the estimated fractional abundances of CH_(3)OCHO(v=0)and CH_(3)OCHO(v=1)are(1.90±0.9)×10^(-9)and(8.90±0.8)×10^(-10),respectively.We also created the integrated emission maps of the detected molecules,and the observed molecules may have originated from the extended envelope of the protostar.We show that C_(2)H_(5)CNand HC_(3)N are most probably formed via the subsequential hydrogenation of the CH_(2)CHCNand the reaction between C_(2)H_(2)and CN on the grain surface of IRAS 18089–1732.We found that NH_(2)CHO is probably produced due to the reaction between NH_(2)and H_(2)CO in the gas phase.Similarly,CH_(3)OCHO is possibly created via the reaction between radical CH_(3)O and radical HCO on the grain surface of IRAS 18089–1732.展开更多
This paper reports that low-temperature heat capacities of 4-(2-aminoethyl)-phenol (C8H11NO) are measured by a precision automated adiabatic calorimeter over the temperature range from 78 to 400 K. A polynomial eq...This paper reports that low-temperature heat capacities of 4-(2-aminoethyl)-phenol (C8H11NO) are measured by a precision automated adiabatic calorimeter over the temperature range from 78 to 400 K. A polynomial equation of heat capacities as a function of the temperature was fitted by the least square method. Based on the fitted polynomial, the smoothed heat capacities and thermodynamic functions of the compound relative to the standard reference temperature 298.15K were calculated and tabulated at the interval of 5K. The energy equivalent, εcalor, of the oxygen-bomb combustion calorimeter has been determined from 0.68g of NIST 39i benzoic acid to be εcalor=(14674.69±17.49)J·K^-1. The constant-volume energy of combustion of the compound at T=298.15 K was measured by a precision oxygen-bomb combustion calorimeter to be ΔcU=-(32374.25±12.93)J·g^-1. The standard molar enthalpy of combustion for the compound was calculated to be ΔcHm = -(4445.47 ± 1.77) kJ·mol^-1 according to the definition of enthalpy of combustion and other thermodynamic principles. Finally, the standard molar enthalpy of formation of the compound was derived to be ΔfHm(C8H11NO, s)=-(274.68 ±2.06) kJ·mol^-1, in accordance with Hess law.展开更多
The general and traditional ways to learn English words are too boring and unsystematic, which is a weak point in students'English learning. The author has conducted a survey among freshmen, sophomores, juniors to...The general and traditional ways to learn English words are too boring and unsystematic, which is a weak point in students'English learning. The author has conducted a survey among freshmen, sophomores, juniors to find out the points,combined the results of the survey with features of memory and storage system, put forward word formation. This essay also presents the advantages of word formation in English vocabulary teaching and learning and introduces five main categories of word formation.展开更多
In a semi-numerical model of reionization, the evolution of ionization fraction is approximately simulated by the criterion of ionizing photon to baryon ratio. We incorporate a semi-analytical model of galaxy formatio...In a semi-numerical model of reionization, the evolution of ionization fraction is approximately simulated by the criterion of ionizing photon to baryon ratio. We incorporate a semi-analytical model of galaxy formation based on the Millennium II N-body simulation into the semi-numerical modeling of reionization. The semianalytical model is used to predict the production of ionizing photons, then we use the semi-numerical method to model the reionization process. Such an approach allows more detailed modeling of the reionization, and also connects observations of galaxies at low and high redshifts to the reionization history. The galaxy formation model we use was designed to match the low-z observations, and it also fits the high redshift luminosity function reasonably well, but its prediction about star formation falls below the observed value, and we find that it also underpredicts the stellar ionizing photon production rate, hence the reionization cannot be completed at z ~ 6. We also consider simple modifications of the model with more top heavy initial mass functions, which can allow the reionization to occur at earlier epochs. The incorporation of the semi-analytical model may also affect the topology of the HI regions during the epoch of reionization, and the neutral regions produced by our simulations with the semi-analytical model, which appeared less poriferous than the simple halo-based models.展开更多
The paper"word—Formation"consists of two parts:component parts ofa word and classes of morphemes and some of the special subclasses. The materialin this paper is written on the basis of my own point of view...The paper"word—Formation"consists of two parts:component parts ofa word and classes of morphemes and some of the special subclasses. The materialin this paper is written on the basis of my own point of view and mostlyon the basis of reference to manny authorities’ publications.展开更多
Nowadays, with the frequent use of English, many Chinese people tend to express with mixed Chinese and English. As to this phenomenon, the thesis mainly analyzes word formation of the mixed Chinese and English. Beginn...Nowadays, with the frequent use of English, many Chinese people tend to express with mixed Chinese and English. As to this phenomenon, the thesis mainly analyzes word formation of the mixed Chinese and English. Beginning with presenting the research background, status and significances, the thesis will employ three parts to clarify this topic.展开更多
文摘This paper introduces China English and China English lexis,and analyzes the four ways of the word-formation of China English lexis:transliteration,loan translation,loan-blend and coinage.The analysis can show that China English is used to express the language system in a special situation in China,and it has brought large number of new lexis and new vision into world Englishes,which has enhanced the expressive force of English.
文摘Chinese noun-classifier compound words show different properties in lexical meaning and syntactic collocation. The complexity of these compounds lies in the grammaticalization of classifiers’ system. Some nouns used as classifiers in the position of classifier are not grammaticalized into real classifiers which are temporary classifiers. So some of them are real noun-classifier compounds and some belong to noun-noun compounds. This paper attempts to analyze the structural relation between noun morpheme and classifier morpheme within the word. It also explains that the noun and the classifier compound in the position of light noun in the nP structure.
文摘In Chinese, compound words denoting kinship axe frequently used. This paper classifies such words into two categories: coordinative and non-coordinative. Each type has subcategories. Under the framework of Distributed Morphology, this paper focuses on the coordinative compound words. They consist of two roots which finally form a NP with the category-giving morpheme. Besides, there are some idioms and infrequent uses which can be explained in the Encyclopedia.
文摘A great deal of new words are emerging and coming into vogue.Most of the previous studies on Chinese new words focused on their classification,form and meaning,as well as the social motivations.This thesis chooses to study the concept metaphor of Chinese new metaphorical compounds from the cognitive perspective based on 396 new words in 2010 and aims to classify the new metaphorical words in a new way and pay attention to the analysis of word formation of new metaphorical compounds.Besides,this paper attempts to explore the understanding process of metaphorical new words.
文摘In English learning most students have difficulty memorizing words and reciting words has become a nation-wide problem for most English learners. This paper introduces a way of word-formation - conversion to help language learners enlarge their vocabulary efficiently.
基金funded by the National Natural Science Foundations of China(Grant Nos.40772121 and 41530207)State Key Projects of Petroleum(Nos.2008ZX05029001,2011ZX05029-001 and 2014A0213)Research and Development Foundations of the Huaneng Clean Energy Research Institute(TY-15-CERI02)
文摘It is important to predict the fracture distribution in the tight reservoirs of the Ordos Basin because fracturing is very crucial for the reconstruction of the low-permeability reservoirs. Three-dimensional finite element models are used to predict the fracture orientation and distribution of the Triassic Yanchang Formation in the Longdong area, southern Ordos Basin. The numerical modeling is based on the distribution of sand bodies in the Chang 7a and 72 members, and the different forces that have been exerted along each boundary of the basin in the Late Mesozoic and the Cenozoic. The calculated results demonstrate that the fracture orientations in the Late Mesozoic and the Ceno- zoic are NW-EW and NNE-ENE, respectively. In this paper, the two-factor method is applied to analyze the distribution of fracture density. The distribution maps of predicted fracture density in the Chang 71 and 72 members are obtained, indicating that the tectonic movement in the Late Mesozoic has a greater influence on the fracture development than that in the Cenozoic. The average fracture densities in the Chang 71 and 72 members are similar, but there are differences in their distributions. Compared with other geological elements, the lithology and the layer thickness are the primary factors that control the stress distribution in the study area, which further determine the fracture distribution in the stable Ordos Basin. The predicted fracture density and the two-factor method can be utilized to guide future exploration in the tight-sand reservoirs.
基金supported by Suzhou Special Project for Diagnosis and Treatment Technology of Clinical Key Diseases(No.LCZX202127)。
文摘Background:miRNAs are closely related to bone metabolism.Studies have shown that Erxian decoction can improve bone metabolism,possibly achieving this regulatory effect through miRNA targets.Netinfer was used to predict the miRNA targets of Erxian decoction for the treatment of postmenopausal osteoporosis,and the results were validated by clinical trials.Methods:In this study,we identified possible targets of Erxian decoction in osteoporosis by means of network pharmacological analysis and bioinformatic prediction.Fifteen cases of postmenopausal osteoporosis with kidney Yin and Yang deficiency(In traditional Chinese medicine,kidney Yin nourishes and moistens the tissues of the internal organs of the body,while kidney Yang promotes and warms the tissues of the internal organs of the body.)were treated with Erxian decoction for four weeks,and serum bone metabolism indices(P1NP,osteocalcin,andβ-CTX)and miRNA-335-5p expression were measured before and after treatment.Results:The constructed miRNA postmenopausal osteoporosis related gene network of the effective compound of the Erxian decoction has 296 points and 981 edges.The 39 postmenopausal osteoporosis related genes regulated by miRNA-335-5p were enriched in ossification,while the signaling pathways were enriched in rheumatoid arthritis,the Toll signaling pathway,the HIF-1 signaling pathway,and the MAPK signaling pathway.After taking Erxian decoction,the expression of the serum bone formation index(P1NP,osteocalcin)and miRNA-335-5p gene expression levels increased significantly.The alterations in P1NP and osteocalcin were correlated with the changes in miRNA-335-5p.Conclusion:Circulating miRNA-335-5p may serve as an important target of Erxian decoction in the treatment of postmenopausal women.The effect of Erxian decoction on bone formation is significant,but the underlying mechanism requires further investigation.
基金supported by the Science Foundation Programs(41302115)
文摘Sandstones attributed to different lacustrine sediment gravity flows are present in the 7th and 6th members of the Yanchang Formation in the Ordos Basin, China. These differences in their origins led to different sandstone distributions which control the scale and connectivity of oil and gas reservoirs. Numerous cores and outcrops were analysed to understand the origins of these sandstones. The main origin of these sandstones was analysed by statistical methods, and well logging data were used to study their vertical and horizontal distributions. Results show that the sandstones in the study area accu- mulated via sandy debris flows, turbidity currents and slumping, and sandy debris flows predominate. The sand- stone associated with a single event is characteristically small in scale and exhibits poor lateral continuity. How- ever, as a result of multiple events that stacked gravity flow-related sandstones atop one another, sandstones are extensive overall, as illustrated in the cross section and isopach maps. Finally, a depositional model was developed in which sandy debris flows predominated and various other types of small-scale gravity flows occurred frequently, resulting in extensive deposition of sand bodies across a large area.
基金supported by the National Natural Science Foundation of China ( 31570940,81772017)
文摘Mechanical stimuli play an essential role in maintaining bone remodeling and skeletal integrity.Meanwhile,bone can respond to the changes of mechanical condition to adjust its mass and architecture.Clinical studies discover that bedridden patients showed osteoporotic T-scores and low bone mineral density,and long-term immobilized patients presented reduced markers of bone formation.However,as bone formation mediated by osteoblast differentiation is a complex process,the underlying molecular mechanism of mechanical stimuli regulating bone formation is still unclear.Recent evidences show that microRNAs(miRNAs)are involved in mechanical stimuli regulating bone formation or osteoblast differentiation.Nevertheless,no direct evidence identifies mechanoresponsive miRNA in both human and animal bones,and clarifies its mechanoresponsive role under different mechanical conditions(e.g.mechanical unloading,reloading,loading).In the current study,we screened for differentially expressed miRNAs in bone specimens of bedridden patients with fractures,then identified that the expression of miR-138-5p,but not the other miRNAs,altered withbedridden time and was negatively correlated with the expression of the bone formation marker genes Alp(alkaline phosphatase).Moreover,miR-138-5p was up-regulated with reduced bone formation during unloading and down-regulated with increased bone formation during reloading in hind4imb unloaded mice.In addition,miR-138-5p was verified to be responsive to different mechanical unloading condition and cyclic mechanical stretch condition in primary osteogenic cells,respectively.Further in vitro data suggested that mechanoresponsive miR-138-5p directly targeted microtubule actin crosslinking factor 1(MACF1)to inhibit osteoblast differentiation.In vivo,we constructed an osteoblastic miR-138-5p transgenic mice model(TG138)with the Runx2promoter,and found that overexpression miR-138-5p supressed bone formation.Moreover,osteoblast-targeted inhibition of miR-138-5p sensitized bone anabolic response to mechanical loading in TG138 mice.Predominantly,the osteoblast-targeted inhibition of miR-138-5p could counteract bone formation reduction induced by hind limb unloading.Taken together,the mechanoresponsive miR-138-5p inhibited bone anabolic response for developing a novel bone anabolic sensitization strategy.
基金supported by the National Natural Science Foundation of China(11172020)Talent Foundation supported by the Fundamental Research Funds for the Central Universities+1 种基金Aerospace Science and Technology Innovation Foundation of China Aerospace Science Corporationthe National High Technology Research and Development Program of China(863)(2012AA120601)
文摘This paper considers nonlinear dynamics of teth- ered three-body formation system with their centre of mass staying on a circular orbit around the Earth, and applies the theory of space manifold dynamics to deal with the nonlinear dynamical behaviors of the equilibrium configurations of the system. Compared with the classical circular restricted three body system, sixteen equilibrium configurations are obtained globally from the geometry of pseudo-potential energy sur- face, four of which were omitted in the previous research. The periodic Lyapunov orbits and their invariant manifolds near the hyperbolic equilibria are presented, and an iteration procedure for identifying Lyapunov orbit is proposed based on the differential correction algorithm. The non-transversal intersections between invariant manifolds are addressed to generate homoclinic and heteroclinic trajectories between the Lyapunov orbits. (3,3)- and (2,1)-heteroclinic trajecto- ries from the neighborhood of one collinear equilibrium to that of another one, and (3,6)- and (2,1)-homoclinic trajecto- ries from and to the neighborhood of the same equilibrium, are obtained based on the Poincar6 mapping technique.
文摘With the deveolpment of the society. and culture, English vocabulary changerapidly. New words enter the English language daily at an ever -- inereasing rate. Greatchange in vocabulary, however, does not cause great change in the rules of English word for-mation. This paper will take some new words as example to show the treat importance of thetraditional principles in the formation of new words, though there are slight changes in themtoo.
基金the Swami Vivekananda Merit-cum-Means Scholarship(SVMCM)for financial support for this research。
文摘The observation of oxygen(O)-and nitrogen(N)-bearing molecules gives an idea about the complex prebiotic chemistry in the interstellar medium.Recent millimeter and submillimeter wavelength observations have shown the presence of complex O-and N-bearing molecules in the star formation regions.So,the investigation of those molecules is crucial to understanding the chemical complexity in the star-forming regions.In this article,we present the identification of the rotational emission lines of N-bearing molecules ethyl cyanide(C_(2)H_(5)CN)and cyanoacetylene(HC_(3)N),and O-bearing molecule methyl formate(CH_(3)OCHO)toward high-mass protostar IRAS18089–1732 using the Atacama Compact Array.We also detected the emission lines of both the N-and O-bearing molecule formamide(NH_(2)CHO)in the envelope of IRAS 18089–1732.We have detected the v=0 and 1 state rotational emission lines of CH_(3)OCHO.We also detected the two vibrationally excited states of HC_(3)N(v7=1 and v7=2).The estimated fractional abundances of C_(2)H_(5)CN,HC_(3)N(v7=1),HC_(3)N(v7=2),and NH_(2)CHO toward IRAS 18089–1732 are(1.40±0.5)×10^(-10),(7.5±0.7)×10^(-11),(3.1±0.4)×10^(-11),and(6.25±0.82)×10^(-11)respectively.Similarly,the estimated fractional abundances of CH_(3)OCHO(v=0)and CH_(3)OCHO(v=1)are(1.90±0.9)×10^(-9)and(8.90±0.8)×10^(-10),respectively.We also created the integrated emission maps of the detected molecules,and the observed molecules may have originated from the extended envelope of the protostar.We show that C_(2)H_(5)CNand HC_(3)N are most probably formed via the subsequential hydrogenation of the CH_(2)CHCNand the reaction between C_(2)H_(2)and CN on the grain surface of IRAS 18089–1732.We found that NH_(2)CHO is probably produced due to the reaction between NH_(2)and H_(2)CO in the gas phase.Similarly,CH_(3)OCHO is possibly created via the reaction between radical CH_(3)O and radical HCO on the grain surface of IRAS 18089–1732.
基金supported by the National Natural Science Foundation of China (Grant No 20673050)
文摘This paper reports that low-temperature heat capacities of 4-(2-aminoethyl)-phenol (C8H11NO) are measured by a precision automated adiabatic calorimeter over the temperature range from 78 to 400 K. A polynomial equation of heat capacities as a function of the temperature was fitted by the least square method. Based on the fitted polynomial, the smoothed heat capacities and thermodynamic functions of the compound relative to the standard reference temperature 298.15K were calculated and tabulated at the interval of 5K. The energy equivalent, εcalor, of the oxygen-bomb combustion calorimeter has been determined from 0.68g of NIST 39i benzoic acid to be εcalor=(14674.69±17.49)J·K^-1. The constant-volume energy of combustion of the compound at T=298.15 K was measured by a precision oxygen-bomb combustion calorimeter to be ΔcU=-(32374.25±12.93)J·g^-1. The standard molar enthalpy of combustion for the compound was calculated to be ΔcHm = -(4445.47 ± 1.77) kJ·mol^-1 according to the definition of enthalpy of combustion and other thermodynamic principles. Finally, the standard molar enthalpy of formation of the compound was derived to be ΔfHm(C8H11NO, s)=-(274.68 ±2.06) kJ·mol^-1, in accordance with Hess law.
文摘The general and traditional ways to learn English words are too boring and unsystematic, which is a weak point in students'English learning. The author has conducted a survey among freshmen, sophomores, juniors to find out the points,combined the results of the survey with features of memory and storage system, put forward word formation. This essay also presents the advantages of word formation in English vocabulary teaching and learning and introduces five main categories of word formation.
基金supported by the MOST 863 Project (No. 2012AA121701)the National Natural Science Foundation of China (Grant No. 11073024)+1 种基金CAS grant KJCX2-EW-W01the John Templeton Foundation
文摘In a semi-numerical model of reionization, the evolution of ionization fraction is approximately simulated by the criterion of ionizing photon to baryon ratio. We incorporate a semi-analytical model of galaxy formation based on the Millennium II N-body simulation into the semi-numerical modeling of reionization. The semianalytical model is used to predict the production of ionizing photons, then we use the semi-numerical method to model the reionization process. Such an approach allows more detailed modeling of the reionization, and also connects observations of galaxies at low and high redshifts to the reionization history. The galaxy formation model we use was designed to match the low-z observations, and it also fits the high redshift luminosity function reasonably well, but its prediction about star formation falls below the observed value, and we find that it also underpredicts the stellar ionizing photon production rate, hence the reionization cannot be completed at z ~ 6. We also consider simple modifications of the model with more top heavy initial mass functions, which can allow the reionization to occur at earlier epochs. The incorporation of the semi-analytical model may also affect the topology of the HI regions during the epoch of reionization, and the neutral regions produced by our simulations with the semi-analytical model, which appeared less poriferous than the simple halo-based models.
文摘The paper"word—Formation"consists of two parts:component parts ofa word and classes of morphemes and some of the special subclasses. The materialin this paper is written on the basis of my own point of view and mostlyon the basis of reference to manny authorities’ publications.
文摘Nowadays, with the frequent use of English, many Chinese people tend to express with mixed Chinese and English. As to this phenomenon, the thesis mainly analyzes word formation of the mixed Chinese and English. Beginning with presenting the research background, status and significances, the thesis will employ three parts to clarify this topic.