Neural stem cells,which are capable of multi-potential differentiation and self-renewal,have recently been shown to have clinical potential for repairing central nervous system tissue damage.However,the theme trends a...Neural stem cells,which are capable of multi-potential differentiation and self-renewal,have recently been shown to have clinical potential for repairing central nervous system tissue damage.However,the theme trends and knowledge structures for human neural stem cells have not yet been studied bibliometrically.In this study,we retrieved 2742 articles from the PubMed database from 2013 to 2018 using "Neural Stem Cells" as the retrieval word.Co-word analysis was conducted to statistically quantify the characteristics and popular themes of human neural stem cell-related studies.Bibliographic data matrices were generated with the Bibliographic Item Co-Occurrence Matrix Builder.We identified 78 high-frequency Medical Subject Heading(MeSH)terms.A visual matrix was built with the repeated bisection method in gCLUTO software.A social network analysis network was generated with Ucinet 6.0 software and GraphPad Prism 5 software.The analyses demonstrated that in the 6-year period,hot topics were clustered into five categories.As suggested by the constructed strategic diagram,studies related to cytology and physiology were well-developed,whereas those related to neural stem cell applications,tissue engineering,metabolism and cell signaling,and neural stem cell pathology and virology remained immature.Neural stem cell therapy for stroke and Parkinson’s disease,the genetics of microRNAs and brain neoplasms,as well as neuroprotective agents,Zika virus,Notch receptor,neural crest and embryonic stem cells were identified as emerging hot spots.These undeveloped themes and popular topics are potential points of focus for new studies on human neural stem cells.展开更多
针对室外大范围场景移动机器人建图中,激光雷达里程计位姿计算不准确导致SLAM(simultaneous localization and mapping)算法精度下降的问题,提出一种基于多传感信息融合的SLAM语义词袋优化算法MSW-SLAM(multi-sensor information fusion...针对室外大范围场景移动机器人建图中,激光雷达里程计位姿计算不准确导致SLAM(simultaneous localization and mapping)算法精度下降的问题,提出一种基于多传感信息融合的SLAM语义词袋优化算法MSW-SLAM(multi-sensor information fusion SLAM based on semantic word bags)。采用视觉惯性系统引入激光雷达原始观测数据,并通过滑动窗口实现了IMU(inertia measurement unit)量测、视觉特征和激光点云特征的多源数据联合非线性优化;最后算法利用视觉与激光雷达的语义词袋互补特性进行闭环优化,进一步提升了多传感器融合SLAM系统的全局定位和建图精度。实验结果显示,相比于传统的紧耦合双目视觉惯性里程计和激光雷达里程计定位,MSW-SLAM算法能够有效探测轨迹中的闭环信息,并实现高精度的全局位姿图优化,闭环检测后的点云地图具有良好的分辨率和全局一致性。展开更多
基金supported by the National Natural Science Foundation of China,No.81471308(to JL)the Stem Cell Clinical Research Project in China,No.CMR-20161129-1003(to JL)the Innovation Technology Funding of Dalian in China,No.2018J11CY025(to JL)
文摘Neural stem cells,which are capable of multi-potential differentiation and self-renewal,have recently been shown to have clinical potential for repairing central nervous system tissue damage.However,the theme trends and knowledge structures for human neural stem cells have not yet been studied bibliometrically.In this study,we retrieved 2742 articles from the PubMed database from 2013 to 2018 using "Neural Stem Cells" as the retrieval word.Co-word analysis was conducted to statistically quantify the characteristics and popular themes of human neural stem cell-related studies.Bibliographic data matrices were generated with the Bibliographic Item Co-Occurrence Matrix Builder.We identified 78 high-frequency Medical Subject Heading(MeSH)terms.A visual matrix was built with the repeated bisection method in gCLUTO software.A social network analysis network was generated with Ucinet 6.0 software and GraphPad Prism 5 software.The analyses demonstrated that in the 6-year period,hot topics were clustered into five categories.As suggested by the constructed strategic diagram,studies related to cytology and physiology were well-developed,whereas those related to neural stem cell applications,tissue engineering,metabolism and cell signaling,and neural stem cell pathology and virology remained immature.Neural stem cell therapy for stroke and Parkinson’s disease,the genetics of microRNAs and brain neoplasms,as well as neuroprotective agents,Zika virus,Notch receptor,neural crest and embryonic stem cells were identified as emerging hot spots.These undeveloped themes and popular topics are potential points of focus for new studies on human neural stem cells.
文摘针对室外大范围场景移动机器人建图中,激光雷达里程计位姿计算不准确导致SLAM(simultaneous localization and mapping)算法精度下降的问题,提出一种基于多传感信息融合的SLAM语义词袋优化算法MSW-SLAM(multi-sensor information fusion SLAM based on semantic word bags)。采用视觉惯性系统引入激光雷达原始观测数据,并通过滑动窗口实现了IMU(inertia measurement unit)量测、视觉特征和激光点云特征的多源数据联合非线性优化;最后算法利用视觉与激光雷达的语义词袋互补特性进行闭环优化,进一步提升了多传感器融合SLAM系统的全局定位和建图精度。实验结果显示,相比于传统的紧耦合双目视觉惯性里程计和激光雷达里程计定位,MSW-SLAM算法能够有效探测轨迹中的闭环信息,并实现高精度的全局位姿图优化,闭环检测后的点云地图具有良好的分辨率和全局一致性。
