A history of the Islamic studies in China,not only includes studies on world Islam,it also includes research on Islam and Muslims in China.Before the Reform and Opening Up,China did not achieve much in this field,sinc...A history of the Islamic studies in China,not only includes studies on world Islam,it also includes research on Islam and Muslims in China.Before the Reform and Opening Up,China did not achieve much in this field,since then,the research field of Islam and Muslim in China has been expanding and the results have been published,forming a new trend.In this field,scholars such as Jin Yijiu,Li Xinghua,Qin Huibin,Zhou Guoli,Sha Qiuzhen,Zhou Xiefan,Wu Yungui,and Yang Huaizhong have made the most outstanding achievements.Especially in the collation of reference books and historical materials,in the past 20 years,The Encyclopedia of the history of Islam,The Chinese Encyclopedia of Islam have emerged,and the Chinese and World Encyclopedia of Islamic Law and other important historical books have been published.This paper focuses on the field of historical research and divided into academic research history at home and abroad,which is discussed from several fields such as general history,special history,national history,and regional history.展开更多
The year 2005 marks the 60th anniversary of the victory of the Chinese People’s War of Resistance Against Japanese Aggression and the world’s anti-fascist war. China and many other countries have held all kinds of a...The year 2005 marks the 60th anniversary of the victory of the Chinese People’s War of Resistance Against Japanese Aggression and the world’s anti-fascist war. China and many other countries have held all kinds of activities to commemorate this event that has most deeply impacted human history. The Second World War, the crudest war展开更多
Based on Fillmore’s frame theory, this paper examines the translator’s cognitive frame operation in the English subtitle translation of Quanzhou’s World Heritage application documentary. It analyzes and discusses h...Based on Fillmore’s frame theory, this paper examines the translator’s cognitive frame operation in the English subtitle translation of Quanzhou’s World Heritage application documentary. It analyzes and discusses how the translator maximizes translation effect between the source language and the target language, so as to enhance the readability of documentary subtitles and promote the spread of traditional Chinese culture. The findings are as follows: Firstly, in the translation process, the frame operations used by the translator include frame correspondence, intra-frame operations, frame replacement, frame perspective shift and frame transplantation. Secondly, cultural documentaries are full of culture-loaded words, for which the translator usually uses frame transplantation. Thirdly, due to the instantaneous nature of subtitles, intra-frame operations and frame replacement are applied in terms of cultural background of the target language audience. Besides, in order to enhance the audience’s reading experience, there may be some changes of narrative perspective in the English translation of cultural documentaries.展开更多
Marx’s theory of world history is an important part of his materialist conception of history(i.e., historical materialism). Marx and Engels summarized the evolution of social history and the laws behind it based on t...Marx’s theory of world history is an important part of his materialist conception of history(i.e., historical materialism). Marx and Engels summarized the evolution of social history and the laws behind it based on their observations and analyses of human activities and their material conditions in real life and raised the realistic possibility of “transformation of history into world history” in the future. From the Marxist perspective of world history, we attempt to catch a glimpse of his profound, scientific criticism of capitalism and understand the contemporaneity and supercontemporaneity of Marxism. Also, we try to perceive new issues of our time and develop a new theory grounded in the scientific, rational, and universal insights from Marxism. The study of Marx’s theory of world history and criticism of capitalism can help understand today’s major issues such as globalization and anti-globalization. In short, Marx’s theory of world history is of profound theoretical and practical significance.展开更多
Inflammatory bowel disease(IBD)has a low prevalence in the Global South,including Pakistan.While genetics and gut flora,influenced by diet and the environment,can contribute to this,we are exploring the possibility of...Inflammatory bowel disease(IBD)has a low prevalence in the Global South,including Pakistan.While genetics and gut flora,influenced by diet and the environment,can contribute to this,we are exploring the possibility of underdiagnosis.Lack of facilities trained in IBD,scarcity of medications,limited health insurance for specialist referral and the current epidemic of abdominal tuberculosis could be the cause.The increasing diagnosis of IBD among Pakistani immigrants and colorectal carcinoma among the young population might be the result of this.Timely referrals by primary care physicians to gastroenterologists,along with the growing use of newer technologies such as abdominal ultrasound for diagnosis can help mitigate the challenge of low or late diagnosis of this chronic condition.展开更多
Memories regarding the history of the Second Sino-Japanese War (1931-1945) and World War il (1939-1945) have always been refreshed in the minds of contemporaries through the retelling of "historical war stories"...Memories regarding the history of the Second Sino-Japanese War (1931-1945) and World War il (1939-1945) have always been refreshed in the minds of contemporaries through the retelling of "historical war stories" in various forms including books, posters, films and other media presentations. However, these retellings are often criticised by some academics as distortion of historical facts. This is because many of the present generation of readers and audiences were not even born at the time the events happened. Thus, "historical facts" of this era are, in reality, very vague in people's minds and their "facts" are often simply a construction of frequently retold "historical war stories" mixed with imagination. This article will argue that even immediately after the end of both wars in 1945, fresh history memory was already distorted, with China being the main victim. Following the end of World War II, there was an extensive publication of books and periodicals about the war. However, through varied interpretations of primary sources and use of visual materials in different ways, various positions were created to suit specific needs for justification of China's desire to be part of the camp of world powers after 1945. Similar diverse positions were also used to make political arguments criticising both the Axis and Allied Powers for working toward different political ends.展开更多
1.Date:August 25-29,1997(Monday-Friday),fora duration of 5 days including a one-dayvisit to the Xianghai Bird Reserve2 Venue:Northeast Normal UniversityChangchun,Northeast of P.R.China3. Sponsorship:Northeast Normal U...1.Date:August 25-29,1997(Monday-Friday),fora duration of 5 days including a one-dayvisit to the Xianghai Bird Reserve2 Venue:Northeast Normal UniversityChangchun,Northeast of P.R.China3. Sponsorship:Northeast Normal University andThe Society of Ancient World History in China(SAWHC).4. Topics:The main topics are as follows:(1) The Origins and Rise of AncientCivilizations(2) The Nature and Characteristics ofAncient Civilizations(3) The Features and Aspects of VariousAncient Civilizations:a. Economy b. Social Conditionsc. Politics d. Religions e. Historiographyf. Science and Philosophy g. Literatureh. Archaeology and Art i. Family andWomen's Status(4) The Development and Connections ofAncient展开更多
Crohn’s disease is a chronic inflammatory disease process involving different sites in the gastrointestinal tract. Occasionally, so-called metastatic disease occurs in extra-intestinal sites. Granulomatous...Crohn’s disease is a chronic inflammatory disease process involving different sites in the gastrointestinal tract. Occasionally, so-called metastatic disease occurs in extra-intestinal sites. Granulomatous inflammation may be detected in endoscopic biopsies or resected tissues. Genetic, epigenetic and environmental factors appear to play a role. Multiple susceptibility genes have been described in both familial and non-familial forms while the disease is phenotypically heterogeneous with a female predominance. The disorder occurs over a broad age spectrum, from early childhood to late adulthood. More than 80% are diagnosed before age 40 years usually with terminal ileal and colonic involvement. Pediatric-onset disease is more severe and more extensive, usually with a higher chance of upper gastrointestinal tract disease, compared to adult-onset disease. Long-term studies have shown that the disorder may evolve with time into more complex disease with stricture formation and penetrating disease complications (i.e., fistula, abscess). Although prolonged remission may occur, discrete periods of symptomatic disease may re-appear over many decades suggesting recurrence or re-activation of this inflammatory process. Eventual development of a cure will likely depend on identification of an etiologic cause and a fundamental understanding of its pathogenesis. Until now, treatment has focused on removing risk factors, particularly cigarette smoking, and improving symptoms. In clinical trials, clinical remission is largely defined as improved numerical and endoscopic indices for “mucosal healing”. “Deep remission” is a conceptual, more “extended” goal that may or may not alter the long-term natural history of the disease in selected patients, albeit at a significant risk for treatment complications, including serious and unusual opportunistic infections.展开更多
World heritage possesses various kinds of use value and non-use value. Measuring the recreational value of world heritage sites is a key issue in the heritage tourism. This paper employs Contingent Valuation Method (C...World heritage possesses various kinds of use value and non-use value. Measuring the recreational value of world heritage sites is a key issue in the heritage tourism. This paper employs Contingent Valuation Method (CVM), which is an evaluation instrument on the basis of tourists′ attitude and preference, to measure the recreational value of Jiuzhaigou, one of the World Natural Heritage sites in China, and analyzes the biases in the survey. The results show that: 1) In 2009, Jiuzhaigou′s recreational value was 3.46×108 yuan (RMB), and the per capita Willingness to Pay (WTP) was 137.31 yuan by CVM. Compared with the results of other methods, this result is significantly low. 2) Among the factors that influence Jiuzhaigou tourists′ WTP, psychological perception factors have the greatest effect while demographic and socio-economic characteristics have a small effect on WTP. 3) The virtuality in CVM creates biases both from CVM itself and in the procedures that CVM was implemented. The former includes hypothetical bias, information bias, protest response bias, and strategic bias; and the latter includes the questionnaire design, population and sample definition, sampling and data processing. The paper analyses those biases and illustrates their potential in-fluences on the accuracy of CVM measurement. 4) Although there are various defects in CVM measurement, it is still an effective valuation method.展开更多
AIM To investigate the differences in family history of inflammatory bowel disease(IBD) and clinical outcomes among individuals with Crohn's disease(CD) residing in China and the United States.METHODS We performed...AIM To investigate the differences in family history of inflammatory bowel disease(IBD) and clinical outcomes among individuals with Crohn's disease(CD) residing in China and the United States.METHODS We performed a survey-based cross-sectional study of participants with CD recruited from China and the United States.We compared the prevalence of IBD family history and history of ileal involvement,CD-related surgeries and IBD medications in China and the United States,adjusting for potential confounders.RESULTS We recruited 49 participants from China and 145 from the United States.The prevalence of family history of IBD was significantly lower in China compared with the United States(China:4.1%,United States:39.3%).The three most commonly affected types of relatives were cousin,sibling,and parent in the United States compared with child and sibling in China.Ileal involvement(China:63.3%,United States:63.5%) and surgery for CD(China:51.0%,United States:49.7%) were nearly equivalent in the two countries.CONCLUSION The lower prevalence of familial clustering of IBD in China may suggest that the etiology of CD is less attributed to genetic background or a family-shared environment compared with the United States.Despite the potential difference in etiology,surgery and ileal involvement were similar in the two countries.Examining the changes in family history during the continuing rise in IBD may provide further insight into the etiology of CD.展开更多
Crohn’s disease is a chronic inflammatory granulomatous process that usually involves different sites in the intestinal tract. Genetic and environmental factors are thought to play a role in its etiology and pathogen...Crohn’s disease is a chronic inflammatory granulomatous process that usually involves different sites in the intestinal tract. Genetic and environmental factors are thought to play a role in its etiology and pathogenesis. The disorder has a heterogeneous clinical expression and data from tertiary care settings have documented its female predominance, occasional familial nature, and high rate of stricture formation and penetrating disease. It may appear from early childhood to late adulthood, although over 80% are currently diagnosed before age 40 years, usually with terminal ileal and colonic involvement. Several studies have now shown differences in phenotypic clinical expression depending on the initial age at diagnosis, with pediatric-onset disease being more severe and more extensive with more involvement of the upper gastrointestinal tract compared to adult-onset disease. In addition, long- term studies from these tertiary care settings have documented that the disorder may evolve with time into a more complex disease with stricture formation and penetrating disease complications (i.e. fistula and abscess). Although prolonged remission with no evidence of inflammatory disease may occur, discrete periods of symptomatic and active granulomatous inflammatory disease may re-appear over many decades. Long-term studies on the natural history have also suggested that discrete events (or agents) may precipitate this granulomatous inflammatory process.展开更多
The Junggar Basin in the northern part of Xinjiang is the second largest inland basin in China. It is located between the Altai and Tianshan Mountains, which is bounded by the Junggar bounded Mountain in the northwest...The Junggar Basin in the northern part of Xinjiang is the second largest inland basin in China. It is located between the Altai and Tianshan Mountains, which is bounded by the Junggar bounded Mountain in the northwest, the Altai Mountains in the northeast and the North Tianshan Mountains in the south. It belongs to a triangular close inland basin, and extends 700 km in EW and 370 km in NS, covering an area of 38x104 km2. The elevation is about 400 m, high in the east (about 1000 m) and low in the west. The central basin is the Guerbantonggute desert, which accounts for 36.9% of the total basin area.展开更多
Inflammatory bowel diseases(IBD),including ulcerative colitis(UC) and Crohn's disease(CD),are chronic,progressive and disabling disorders.Over the last few decades,new therapeutic approaches have been introduced w...Inflammatory bowel diseases(IBD),including ulcerative colitis(UC) and Crohn's disease(CD),are chronic,progressive and disabling disorders.Over the last few decades,new therapeutic approaches have been introduced which have led not only to a reduction in the mortality rate but also offered the possibility of a favorable modification in the natural history of IBD.The identification of clinical,genetic and serological prognostic factors has permitted a better stratification of the disease,thus allowing the opportunity to indicate the most appropriate therapy.Early treatment with immunosuppressive drugs and biologics has offered the opportunity to change,at least in the short term,the course of the disease by reducing,in a subset of patients with IBD,hospitalization and the need for surgery.In this review,the crucial steps in the natural history of both UC and CD will be discussed,as well as the factors that may change their clinical course.The methodological requirements for high quality studies on the course and prognosis of IBD,the true impact of environmental and dietary factors on the clinical course of IBD,the clinical,serological and genetic predictors of the IBD course(in particular,which of these are rel-evant and appropriate for use in clinical practice),the impact of the various forms of medical treatment on the IBD complication rate,the role of surgery for IBD in the biologic era,the true magnitude of risk of colorectal cancer associated with IBD,as well as the mortality rate related to IBD will be stressed;all topics that are extensively discussed in separate reviews included in this issue of World Journal of Gastroenterology.展开更多
The Xinjiang Geology and Mineral Resources Exploration and Development Bureau have conducted a detailed investigation project of the Xigobi soda-niter deposit in Hami, Xinjiang Province, which was completed at the end...The Xinjiang Geology and Mineral Resources Exploration and Development Bureau have conducted a detailed investigation project of the Xigobi soda-niter deposit in Hami, Xinjiang Province, which was completed at the end of 2011. The project put much emphasis on research of soda-niter mineralization rules, stratum classification, ore-forming展开更多
Crohn’s disease (CD) is a multifactorial potentially debilitating disease. It has a variable disease course, but the majority of patients eventually develop penetrating or stricturing complications leading...Crohn’s disease (CD) is a multifactorial potentially debilitating disease. It has a variable disease course, but the majority of patients eventually develop penetrating or stricturing complications leading to repeated surgeries and disability. Studies on the natural history of CD provide invaluable data on its course and clinical predictors, and may help to identify patient subsets based on clinical phenotype. Most data are available from referral centers, however these outcomes may be different from those in population-based cohorts. New data suggest the possibility of a change in the natural history in Crohn’s disease, with an increasing percentage of patients diagnosed with inflammatory disease behavior. Hospitalization rates remain high, while surgery rates seem to have decreased in the last decade. In addition, mortality rates still exceed that of the general population. The impact of changes in treatment strategy, including increased, earlier use of immunosuppressives, biological therapy, and patient monitoring on the natural history of the disease are still conflictive. In this review article, the authors summarize the available evidence on the natural history, current trends, and predictive factors for evaluating the disease course of CD.展开更多
In the year of 2011, a superlarge molybdenum deposit was discovered in the Shapinggou area, Jinzhai county, Anhui Province by the Bureau of Geology and Mineral Exploration of Anhui Province, with its reserve more than...In the year of 2011, a superlarge molybdenum deposit was discovered in the Shapinggou area, Jinzhai county, Anhui Province by the Bureau of Geology and Mineral Exploration of Anhui Province, with its reserve more than 2.2 million ton, just next to the Klimax molybdenum deposit (〉3.3 million ton) in Colorado. It has ranged the world's second largest molybdenum deposit, with potential economic value up to 100 billion dollars.展开更多
文摘A history of the Islamic studies in China,not only includes studies on world Islam,it also includes research on Islam and Muslims in China.Before the Reform and Opening Up,China did not achieve much in this field,since then,the research field of Islam and Muslim in China has been expanding and the results have been published,forming a new trend.In this field,scholars such as Jin Yijiu,Li Xinghua,Qin Huibin,Zhou Guoli,Sha Qiuzhen,Zhou Xiefan,Wu Yungui,and Yang Huaizhong have made the most outstanding achievements.Especially in the collation of reference books and historical materials,in the past 20 years,The Encyclopedia of the history of Islam,The Chinese Encyclopedia of Islam have emerged,and the Chinese and World Encyclopedia of Islamic Law and other important historical books have been published.This paper focuses on the field of historical research and divided into academic research history at home and abroad,which is discussed from several fields such as general history,special history,national history,and regional history.
文摘The year 2005 marks the 60th anniversary of the victory of the Chinese People’s War of Resistance Against Japanese Aggression and the world’s anti-fascist war. China and many other countries have held all kinds of activities to commemorate this event that has most deeply impacted human history. The Second World War, the crudest war
文摘Based on Fillmore’s frame theory, this paper examines the translator’s cognitive frame operation in the English subtitle translation of Quanzhou’s World Heritage application documentary. It analyzes and discusses how the translator maximizes translation effect between the source language and the target language, so as to enhance the readability of documentary subtitles and promote the spread of traditional Chinese culture. The findings are as follows: Firstly, in the translation process, the frame operations used by the translator include frame correspondence, intra-frame operations, frame replacement, frame perspective shift and frame transplantation. Secondly, cultural documentaries are full of culture-loaded words, for which the translator usually uses frame transplantation. Thirdly, due to the instantaneous nature of subtitles, intra-frame operations and frame replacement are applied in terms of cultural background of the target language audience. Besides, in order to enhance the audience’s reading experience, there may be some changes of narrative perspective in the English translation of cultural documentaries.
基金a phased research result of“Study of‘Building a Community with a Shared Future for Mankind’Vision from the Marxist Perspective of World History”(19BKS51)a program funded by the National Social Science Fund of China(NSSFC)。
文摘Marx’s theory of world history is an important part of his materialist conception of history(i.e., historical materialism). Marx and Engels summarized the evolution of social history and the laws behind it based on their observations and analyses of human activities and their material conditions in real life and raised the realistic possibility of “transformation of history into world history” in the future. From the Marxist perspective of world history, we attempt to catch a glimpse of his profound, scientific criticism of capitalism and understand the contemporaneity and supercontemporaneity of Marxism. Also, we try to perceive new issues of our time and develop a new theory grounded in the scientific, rational, and universal insights from Marxism. The study of Marx’s theory of world history and criticism of capitalism can help understand today’s major issues such as globalization and anti-globalization. In short, Marx’s theory of world history is of profound theoretical and practical significance.
文摘Inflammatory bowel disease(IBD)has a low prevalence in the Global South,including Pakistan.While genetics and gut flora,influenced by diet and the environment,can contribute to this,we are exploring the possibility of underdiagnosis.Lack of facilities trained in IBD,scarcity of medications,limited health insurance for specialist referral and the current epidemic of abdominal tuberculosis could be the cause.The increasing diagnosis of IBD among Pakistani immigrants and colorectal carcinoma among the young population might be the result of this.Timely referrals by primary care physicians to gastroenterologists,along with the growing use of newer technologies such as abdominal ultrasound for diagnosis can help mitigate the challenge of low or late diagnosis of this chronic condition.
文摘Memories regarding the history of the Second Sino-Japanese War (1931-1945) and World War il (1939-1945) have always been refreshed in the minds of contemporaries through the retelling of "historical war stories" in various forms including books, posters, films and other media presentations. However, these retellings are often criticised by some academics as distortion of historical facts. This is because many of the present generation of readers and audiences were not even born at the time the events happened. Thus, "historical facts" of this era are, in reality, very vague in people's minds and their "facts" are often simply a construction of frequently retold "historical war stories" mixed with imagination. This article will argue that even immediately after the end of both wars in 1945, fresh history memory was already distorted, with China being the main victim. Following the end of World War II, there was an extensive publication of books and periodicals about the war. However, through varied interpretations of primary sources and use of visual materials in different ways, various positions were created to suit specific needs for justification of China's desire to be part of the camp of world powers after 1945. Similar diverse positions were also used to make political arguments criticising both the Axis and Allied Powers for working toward different political ends.
文摘1.Date:August 25-29,1997(Monday-Friday),fora duration of 5 days including a one-dayvisit to the Xianghai Bird Reserve2 Venue:Northeast Normal UniversityChangchun,Northeast of P.R.China3. Sponsorship:Northeast Normal University andThe Society of Ancient World History in China(SAWHC).4. Topics:The main topics are as follows:(1) The Origins and Rise of AncientCivilizations(2) The Nature and Characteristics ofAncient Civilizations(3) The Features and Aspects of VariousAncient Civilizations:a. Economy b. Social Conditionsc. Politics d. Religions e. Historiographyf. Science and Philosophy g. Literatureh. Archaeology and Art i. Family andWomen's Status(4) The Development and Connections ofAncient
文摘Crohn’s disease is a chronic inflammatory disease process involving different sites in the gastrointestinal tract. Occasionally, so-called metastatic disease occurs in extra-intestinal sites. Granulomatous inflammation may be detected in endoscopic biopsies or resected tissues. Genetic, epigenetic and environmental factors appear to play a role. Multiple susceptibility genes have been described in both familial and non-familial forms while the disease is phenotypically heterogeneous with a female predominance. The disorder occurs over a broad age spectrum, from early childhood to late adulthood. More than 80% are diagnosed before age 40 years usually with terminal ileal and colonic involvement. Pediatric-onset disease is more severe and more extensive, usually with a higher chance of upper gastrointestinal tract disease, compared to adult-onset disease. Long-term studies have shown that the disorder may evolve with time into more complex disease with stricture formation and penetrating disease complications (i.e., fistula, abscess). Although prolonged remission may occur, discrete periods of symptomatic disease may re-appear over many decades suggesting recurrence or re-activation of this inflammatory process. Eventual development of a cure will likely depend on identification of an etiologic cause and a fundamental understanding of its pathogenesis. Until now, treatment has focused on removing risk factors, particularly cigarette smoking, and improving symptoms. In clinical trials, clinical remission is largely defined as improved numerical and endoscopic indices for “mucosal healing”. “Deep remission” is a conceptual, more “extended” goal that may or may not alter the long-term natural history of the disease in selected patients, albeit at a significant risk for treatment complications, including serious and unusual opportunistic infections.
基金Under the auspices of Sino-British Fellowship by the British Academy (No. SG-47266)National Natural Science Foundation of China (No. 40371030)
文摘World heritage possesses various kinds of use value and non-use value. Measuring the recreational value of world heritage sites is a key issue in the heritage tourism. This paper employs Contingent Valuation Method (CVM), which is an evaluation instrument on the basis of tourists′ attitude and preference, to measure the recreational value of Jiuzhaigou, one of the World Natural Heritage sites in China, and analyzes the biases in the survey. The results show that: 1) In 2009, Jiuzhaigou′s recreational value was 3.46×108 yuan (RMB), and the per capita Willingness to Pay (WTP) was 137.31 yuan by CVM. Compared with the results of other methods, this result is significantly low. 2) Among the factors that influence Jiuzhaigou tourists′ WTP, psychological perception factors have the greatest effect while demographic and socio-economic characteristics have a small effect on WTP. 3) The virtuality in CVM creates biases both from CVM itself and in the procedures that CVM was implemented. The former includes hypothetical bias, information bias, protest response bias, and strategic bias; and the latter includes the questionnaire design, population and sample definition, sampling and data processing. The paper analyses those biases and illustrates their potential in-fluences on the accuracy of CVM measurement. 4) Although there are various defects in CVM measurement, it is still an effective valuation method.
基金Supported by (in part)Johns Hopkins Institute for Clinical and Translational Research,No.UL1TR001079
文摘AIM To investigate the differences in family history of inflammatory bowel disease(IBD) and clinical outcomes among individuals with Crohn's disease(CD) residing in China and the United States.METHODS We performed a survey-based cross-sectional study of participants with CD recruited from China and the United States.We compared the prevalence of IBD family history and history of ileal involvement,CD-related surgeries and IBD medications in China and the United States,adjusting for potential confounders.RESULTS We recruited 49 participants from China and 145 from the United States.The prevalence of family history of IBD was significantly lower in China compared with the United States(China:4.1%,United States:39.3%).The three most commonly affected types of relatives were cousin,sibling,and parent in the United States compared with child and sibling in China.Ileal involvement(China:63.3%,United States:63.5%) and surgery for CD(China:51.0%,United States:49.7%) were nearly equivalent in the two countries.CONCLUSION The lower prevalence of familial clustering of IBD in China may suggest that the etiology of CD is less attributed to genetic background or a family-shared environment compared with the United States.Despite the potential difference in etiology,surgery and ileal involvement were similar in the two countries.Examining the changes in family history during the continuing rise in IBD may provide further insight into the etiology of CD.
文摘Crohn’s disease is a chronic inflammatory granulomatous process that usually involves different sites in the intestinal tract. Genetic and environmental factors are thought to play a role in its etiology and pathogenesis. The disorder has a heterogeneous clinical expression and data from tertiary care settings have documented its female predominance, occasional familial nature, and high rate of stricture formation and penetrating disease. It may appear from early childhood to late adulthood, although over 80% are currently diagnosed before age 40 years, usually with terminal ileal and colonic involvement. Several studies have now shown differences in phenotypic clinical expression depending on the initial age at diagnosis, with pediatric-onset disease being more severe and more extensive with more involvement of the upper gastrointestinal tract compared to adult-onset disease. In addition, long- term studies from these tertiary care settings have documented that the disorder may evolve with time into a more complex disease with stricture formation and penetrating disease complications (i.e. fistula and abscess). Although prolonged remission with no evidence of inflammatory disease may occur, discrete periods of symptomatic and active granulomatous inflammatory disease may re-appear over many decades. Long-term studies on the natural history have also suggested that discrete events (or agents) may precipitate this granulomatous inflammatory process.
文摘The Junggar Basin in the northern part of Xinjiang is the second largest inland basin in China. It is located between the Altai and Tianshan Mountains, which is bounded by the Junggar bounded Mountain in the northwest, the Altai Mountains in the northeast and the North Tianshan Mountains in the south. It belongs to a triangular close inland basin, and extends 700 km in EW and 370 km in NS, covering an area of 38x104 km2. The elevation is about 400 m, high in the east (about 1000 m) and low in the west. The central basin is the Guerbantonggute desert, which accounts for 36.9% of the total basin area.
文摘Inflammatory bowel diseases(IBD),including ulcerative colitis(UC) and Crohn's disease(CD),are chronic,progressive and disabling disorders.Over the last few decades,new therapeutic approaches have been introduced which have led not only to a reduction in the mortality rate but also offered the possibility of a favorable modification in the natural history of IBD.The identification of clinical,genetic and serological prognostic factors has permitted a better stratification of the disease,thus allowing the opportunity to indicate the most appropriate therapy.Early treatment with immunosuppressive drugs and biologics has offered the opportunity to change,at least in the short term,the course of the disease by reducing,in a subset of patients with IBD,hospitalization and the need for surgery.In this review,the crucial steps in the natural history of both UC and CD will be discussed,as well as the factors that may change their clinical course.The methodological requirements for high quality studies on the course and prognosis of IBD,the true impact of environmental and dietary factors on the clinical course of IBD,the clinical,serological and genetic predictors of the IBD course(in particular,which of these are rel-evant and appropriate for use in clinical practice),the impact of the various forms of medical treatment on the IBD complication rate,the role of surgery for IBD in the biologic era,the true magnitude of risk of colorectal cancer associated with IBD,as well as the mortality rate related to IBD will be stressed;all topics that are extensively discussed in separate reviews included in this issue of World Journal of Gastroenterology.
文摘The Xinjiang Geology and Mineral Resources Exploration and Development Bureau have conducted a detailed investigation project of the Xigobi soda-niter deposit in Hami, Xinjiang Province, which was completed at the end of 2011. The project put much emphasis on research of soda-niter mineralization rules, stratum classification, ore-forming
文摘Crohn’s disease (CD) is a multifactorial potentially debilitating disease. It has a variable disease course, but the majority of patients eventually develop penetrating or stricturing complications leading to repeated surgeries and disability. Studies on the natural history of CD provide invaluable data on its course and clinical predictors, and may help to identify patient subsets based on clinical phenotype. Most data are available from referral centers, however these outcomes may be different from those in population-based cohorts. New data suggest the possibility of a change in the natural history in Crohn’s disease, with an increasing percentage of patients diagnosed with inflammatory disease behavior. Hospitalization rates remain high, while surgery rates seem to have decreased in the last decade. In addition, mortality rates still exceed that of the general population. The impact of changes in treatment strategy, including increased, earlier use of immunosuppressives, biological therapy, and patient monitoring on the natural history of the disease are still conflictive. In this review article, the authors summarize the available evidence on the natural history, current trends, and predictive factors for evaluating the disease course of CD.
文摘In the year of 2011, a superlarge molybdenum deposit was discovered in the Shapinggou area, Jinzhai county, Anhui Province by the Bureau of Geology and Mineral Exploration of Anhui Province, with its reserve more than 2.2 million ton, just next to the Klimax molybdenum deposit (〉3.3 million ton) in Colorado. It has ranged the world's second largest molybdenum deposit, with potential economic value up to 100 billion dollars.