Continuity and Change in Dao Yin:Comparing and Contrasting the Therapeutic Exercises in Yin Shu(The Book of Pulling,c.2nd Century BCE)and Zhu Bing Yuan Hou Lun(Treatise on the Origins and Manifestations of Various Diseases,610 CE)

The manuscript Yin Shu(The Book of Pulling),excavated from Zhangjiashan Han Tomb No.247,is the earliest surviving text on therapeutic exercise known as Dao Yin(lit.guiding and pulling).Discovered in 1983,this Dao Yin text,together with the drawings of 44 figures performing“guiding and pulling”exercises found in the Mawangdui Han Tomb in 1974,are of great significance to the study of the early history of Dao Yin.Prior to these discoveries,researchers into Dao Yin relied mainly on material found in the Dao Zang(the Daoist Canon),compiled in 1145.This led to their conclusion that Dao Yin was essentially Daoist.The development of Dao Yin reached its zenith during the Sui Dynasty(581–618 CE),when it became one of the three medical departments at the imperial medical education institution.As part of the medical reform of the second Sui Emperor,Yang Di,Dao Yin became the treatment of choice,and the employment of a large number of Dao Yin specialists to the Sui court transformed the state medical service.The compilation of Zhu Bing Yuan Hou Lun(Treatise on the Origins and Manifestations of Various Diseases)under Yang Di’s decree,incorporated an abundance of resources on Dao Yin,enabling physicians to potentially“prescribe”Dao Yin to their patients.Situating both Yin Shu and Zhu Bing Yuan Hou Lun in their social and historical contexts,this article analyses their editorial treatments,examines their different objectives,styles,and readerships,and compares the various exercises described in the two texts.It emphasizes the fact that over a period of nearly a thousand years,from the late Warring States(475–221 BCE)to the Sui and Tang periods,Dao Yin was an important medical practice,culminating in its institutionalization by the Sui government.

Yuan Ke and Chinese Mythology

Yuan Ke shifted his focus from early literary creation to mythological research,gradually developing a distinctive approach to mythology research,which involves examining the correlation between mythology and literature.Yuan Ke is one of the most exceptional scholars who has made significant contributions to the popularity and promotion of Chinese mythology.He has collected,sorted out,and transformed related materials into stories to facilitate the systematic development of Chinese mythology.Moreover,he proposed and constructed a broad mythology theory,making him a leading figure in contemporary Chinese mythology research.Upon reflecting on the development of Chinese mythology,it is evident that Yuan Ke has progressed from a learner to a trailblazer and finally to the architect of his own comprehensive mythological framework.

Identification of 13th-14th Century Chinese Handmade Paper Fibers Collected in Yuan Dynasty Paper Currencies

The earliest paper currencies in existence in China were handcrafted during the Yuan dynasty.These currencies were scientifically excavated from different ruins or tombs,whereas scientific analyses of the papers are rare.This study used optical and scanning electron microscopy to examine the fibers collected in Yuan dynasty paper currencies in conjunction with the Herzberg staining method.Despite differences in circulation period,paper fibers in both Zhi Yuan Tong Xing Bao Chao(two Guan)and Zhong Tong Yuan Bao Jiao Chao(one Guan and 500 Wen,issued in Zhi Zheng period)were identified as similar papermaking materials,bast fibers of mulberry bark.The results indicate that mulberry bark,a durable papermaking material used since ancient times,was mainly utilized as a raw material in these Yuan dynasty paper currency.This fiber identification work solved the critical problem of papermaking material in the Yuan dynasty paper currency and provided important information for conserving these precious cultural relics.

求解无约束优化问题的Dai-Yuan记忆梯度法

将Dai-Yuan共轭梯度法的前提条件βk>0改为βk<0,根据搜索方向的下降性要求,得出一个新的记忆梯度法,并做出了收敛性证明.新算法与Dai-Yuan共轭梯度法联系紧密.数值实验表明了该算法的有效性.

接枝改性橡Yuan栲胶的性能及其应用

通过使用光学显微镜和扫描电镜，对Yuan栲胶改性产物应用于浸酸山羊皮的鞣制进行了研究，筛选确定最佳的鞣制工艺条件，所得坯革粒面细致，革身丰满柔软，物理机械性能均优于橡Yuan栲胶鞣坯革。

含参数Dai-Yuan共轭梯度法及其收敛性

通过对Dai-Yuan共轭梯度法的分析,将βkDY推广到更一般的形式.根据搜索方向的下降性要求,得出含参数Dai-Yuan共轭梯度法.在Wolfe条件下,证明了方法的收敛性;在强Wolfe条件下,证明了方法的充分下降性.含参数Dai-Yuan共轭梯度法不仅仅是Dai-Yuan共轭梯度法在形式上的推广,其参数的合理选择有望使Dai-Yuan共轭梯度法良好的数值表现得到进一步改善.

The Influence of Aesthetic Ideology of TAO Yuan-ming on Classical Gardens in South China

Based on the contents and temperament of pastoral poetries written by TAO Yuan-ming,by centering on respecting the nature,indifference and optimism,and plainness and authenticity,the paper had analyzed aesthetic ideologies contained in his poetries.On this basis,it had discussed the influence of aesthetic ideology of TAO Yuan-ming on the style of classical gardens in South China,which were quiet and natural,elegant and fresh,simple and plain,and far-reaching in artistic conception.By combining with cases,it pointed out that the poetic prose had been directly quoted as the names of gardens or scenic spots of classical gardens in South China,and showed that the aesthetic ideology of TAO Yuan-ming had set up a successful ideal model for cultural landscapes,producing far-reaching influence on the aesthetic state of mind of gardeners or owners of gardens,further instilling humanistic spirit into classical gardens in South China.

Yuan Museum——精品生活方式美学博物馆

关于Yuan Museum于2019年创办,是一座收藏20世纪现代设计作品以及当代设计的博物馆。Yuan Museum藏品500多件,以生活美学为核心,收藏有家具、艺术地毯、漆器、陶器、首饰、艺术装置等诸多门类,能完整展现出一个世纪以来东西方的生活方式美学的源流与脉络,是中国不可多得的精品生活方式美学博物馆,对设计者和观众极具吸引力。

Yuan Museum——精品生活方式美学博物馆(三)

关于Yuan Museum于2019年创办,是一个收藏20世纪现代设计作品以及当代设计的博物馆。Yuan Museum藏品500多件,以生活美学为核心,收藏有家具、艺术地毯、漆器、陶器、首饰、艺术装置等诸多门类,能完整展现出一个世纪以来东西方的生活方式美学的源流与脉络,是中国不可多得的精品生活方式美学博物馆,对设计者和观众极具吸引力。

Yuan Museum——精品生活方式美学博物馆(二)

关于Yuan Museum于2019年创办,是一个收藏20世纪现代设计作品以及当代设计的博物馆。Yuan Museum藏品500多件,以生活美学为核心,收藏有家具、艺术地毯、漆器、陶器、首饰、艺术装置等诸多门类,能完整展现出一个世纪以来东西方的生活方式美学的源流与脉络,是中国不可多得的精品生活方式美学博物馆,对设计者和观众极具吸引力。

Application of the Mongol-Yuan Culture in the Modern Landscape Design

The application principles of the Mongol-Yuan culture in the landscape elements are found out,through the research on the meaning of Mongol-Yuan culture and the connectivity between culture and landscape elements.The application of the Mongol-Yuan culture is specified by a typical design case analysis so as to offer some references for the modern landscape design.The Mongol-Yuan culture can be applied to the modern landscape elements,such as landform,architecture,sculpture,paving and so on.And the artistic conception of the Mongol-Yuan culture can be created by the application of the Mongolian totem culture,characteristic style,featured pattern,local customs and so on.

The Influence of Miao Nationality’s Culture in Yuan Xiang Region on the Later Poetry Creation of Qu Yuan

Miao culture is one of the minority cultures in China.It also has a certain impact on the development of Chinese literature and poetry.Chu ci is a new poetic style created by Qu Yuan,an ancient poet in China.It is the first collection of romantic poetry in the history of Chinese literature.Qu Yuan’s poetry creation is related to his life experience.Qu Yuan was exiled to Yuan Xiang region,and he had been in contact with the Miao ancestors in Yuan Xiang area during the exile.Therefore,the Miao land culture in Yuan Xiang area has a profound influence on Qu Yuan’s later poetry creation.This paper,taking Qu Yuan’s later poetry as an example,analyzes the influence of Miao culture on Chu ci in Yuan Xiang area,introduces Qu Yuan’s life and how to contact Miao culture,and probes into the influence of Miao nationality’s religious thought,customs,language and culture,oral folk song and pan song on the later poetry creation of Qu Yuan.

拟南芥YUAN1基因调控器官形状和大小

器官形状和大小的控制是一个基本的发育生物学过程,受细胞分裂和细胞扩展的影响。到目前为止,人们对植物器官形状和大小的调控机制知之甚少。本实验室前期研究发现了一个种子和器官大小的调控基因DA1,其编码一个泛素受体。在拟南芥(Arabidopsis thaliana)中,DA1通过抑制细胞的分裂来限制种子和器官的大小。本研究通过激活标签的方法在da1-1突变体背景下筛选到一个叶子形状发生改变的半显性突变体(yuan1-1D)。yuan1-1D形成短而圆的叶片和短的叶柄,细胞学分析显示,叶片和叶柄变短的主要原因是细胞的长向扩展降低导致的。YUAN1编码一个含有PHD锌指结构域的蛋白。GFP-YUAN1融合蛋白定位在细胞核内。过量表达YUAN1基因导致叶片和叶柄变短。遗传学分析显示,YUAN1和DA1、ROT3以及ROT4在控制叶片形状和大小方面作用于不同的遗传途径中。因此,本研究鉴定了一个新的控制器官形状和大小的基因YUAN1,为阐明植物器官形状和大小调控的分子机制提供了重要线索。

Comparative Textual Studies on Bai Hua's Poem Xiatian Hai Hen Yuan and Its English Translations

Based on the poem Xiatian Hai Hen Yuan夏天还很远, one of the most characteristic works of the Chinese poet Bai Hua, along with its four English translations, this paper conducts comparative textual studies with regard to three aspects, including the translation of hidden personae, the selection of the tense and aspectas well as the rendition of poetic rhythms. The author holds the view that, on the one hand, different textual interpretations have gone a long way toward the dissemination of the original poem in the English-speaking world;on the other hand, the translator's proper understanding and rendition is of great significance with a view to a better presentation of the unique beauty of Chinese poetry both in the content and the form.

一类线性等式约束优化的投影Dai-Yuan共轭梯度法及其全局收敛性

针对具有等式约束的非线性最优化问题,提出了一类具有充分下降特性的投影Dai-Yuan共轭梯度法.在每次迭代过程中,算法均可得到充分下降的搜索方向.在适当条件下,证明了算法产生的搜索方向为可行下降方向,分析了算法的全局收敛性.数值结果表明算法是可行的、有效的.

Molecular Biological Mechanisms of Yuan Zhi Powder in the Treatment of Alzheimer's Disease: an Analysis Based on Network Pharmacology

Objective To predict the main active ingredients,potential targets and molecular mechanisms of Yuan Zhi powder in treatment of dementia by using network pharmacology.Methods A database of chemical constituents of Yuan Zhi powder was constructed by using databases and literatures.Potential targets were predicted by reverse molecular docking,and then a component-target network was constructed.The target network of Alzheimer's disease(AD)was mapped and analyzed to obtain the“active ingredient-AD target”network.The key targets were screened through network analysis.Finally,the rationality of the prediction was analyzed by comparing with the target reported in the literatures.Results There were180chemical constituents acting on the AD target,and the targets included three key targets(cyclooxygenase-2,muscarinic acetylcholine receptor M1,and muscarinic acetylcholine receptor M2)and an important target(acetylcholine esterase).Alzheimer's disease may be treated by regulating the activity of acetylcholine receptors and the binding toβ-amyloid protein,and its biological process may be concentrated in the acetylcholine receptor signal pathway,negative regulation of synaptic transmission and so on.Conclusion The fact that Yuan Zhi powder can treat AD is consistent with the characteristics of multi-components-multitargets-multiple pathways of traditional Chinese medicine.The important targets obtained from network analysis have a large proportion in literature research,so network analysis have some rationality.

Anti-inflammatory and Analgesic Effects of Bi-yuan-ling Granules

Bi-yuan-ling granule（BLG） is a traditional Chinese medicine compound composed mainly of baicalin and chlorogenic acid. It has been demonstrated to be clinically effective for various inflammatory diseases such as acute rhinitis, chronic rhinitis, atrophic rhinitis and allergic rhinitis. However, the underlying mechanisms of BLG against these diseases are not fully understood. This study aimed to explore the anti-inflammatory and analgesic activities of BLG, and examine its protective effects on mouse acute lung injury（ALI）. The hot plate test and acetic acid-induced writhing assay in Kunming mice were adopted to evaluate the pain-relieving effects of BLG. The anti-inflammatory activities of BLG were determined by examining the effects of BLG on xylene-caused ear swelling in Kunming mice, the cotton pellet-induced granuloma in rats, carrageenan-induced hind paw edema and lipopolysaccharide（LPS）-induced acute lung injury（ALI） in mice. The results showed that BLG at 15.5 mg/g could significantly relieve the pain by 82.5%（P〈0.01） at 1 h after thermal stimulation and 91.2%（P〈0.01） at 2 h after thermal stimulation. BLG at doses of 7.75 and 15.5 mg/g reduced the writhing count up to 33.3%（P〈0.05） and 53.4%（P〈0.01）, respectively. Additionally, the xylene-induced edema in mice was markedly restrained by BLG at 7.75 mg/g（P〈0.05） and 15.5 mg/g（P〈0.01）. BLG at 5.35 and 10.7 mg/g significantly reduced paw edema by 34.8%（P〈0.05） and 37.9%（P〈0.05） at 5 h after carrageenan injection. The granulomatous formation of the cotton pellet was profoundly suppressed by BLG at 2.68, 5.35 and 10.7 mg/g by 15.4%, 38.2%（P〈0.01） and 58.9%（P〈0.001）, respectively. BLG also inhibited lung W/D ratio and the release of prostaglandin E2（PGE2） in ALI mice. In addition, the median lethal dose（LD_（50））, median effective dose（ED_（50）） and half maximal inhibitory concentration（IC50） of BLG were found to be 42.7, 3.2 and 12.33 mg/g, respectively. All the findings suggest that BLG has significantly anti-inflammatory and analgesic effects and it may help reduce the damage of ALI.

Professor Yuan Cheng (Bert) Fung:My Respected Mentor and Cherished Friend

On September 14,2008,Drs.Shu Chien,Peter Chen,Geert Schmid-Schonbein,Pin Tong and I had the great pleasure of organizing a beautiful event in San Diego,California to celebration Dr.Fung’s 90thbirthday with his students,friends and family[1].The team gave me the honor and privilege to be the banquet speaker.I titled my speech as“Dr.Fung:My Respected Mentor and Cherished Friend”-something for those of you who have known Dr.Fung well can“resonate”.Still,I would like to take this opportunity to share with you an excerpt of the story I told about this great gentle man.

Sun Yuan and Peng Yu

■Since April,all Magazine has examined five artist couples working in China.This month we lookatthe youngest of the artistic duos,Peng Yu and Sun Yuan,whose