Geology and mineralization of the Hongqiling large magmatic nickel-copper-cobalt deposit(22×10^(4)t)in Jilin Province,China:A review

The Hongqiling large nickel-copper-cobalt deposit(hereafter referred to as the Hongqiling deposit),a typical mafic-ultramafic copper-nickel deposit in China,boasts proven Ni(Ni)resources of approximately 22×10^(4)t,associated copper resources of 2×10^(4)t,and associated cobalt(Co)resources of 0.5×10^(4)t,with Ni reserves ranking 10th among China's magmatic nickel deposits.Geotectonically,the Hongqiling deposit is situated in the superimposed zone between the Xing'an-Mongolian orogenic belt and the circum-Western Pacific's active continental margin belt.Its ore-bearing plutons occur within the metamorphic rocks of the Ordovician Hulan Group,with the emplacement of plutons and the locations of orebodies governed by the deep-seated Huifahe fault and its secondary NW-trending Fujia-Hejiagou-Beixinglong-Changsheng fault zone.In the deposit,the rock assemblages of ore-bearing plutons predominantly encompass gabbro-pyroxenite-olivine pyroxenite-pyroxene peridotite(pluton No.1)and norite-orthopyroxenite-harzburgite(pluton No.7),with ore-bearing lithofacies consisting primarily of olivine pyroxenite and pyroxenite facies.The Hongqiling deposit hosts stratoid,overhanging lentoid,veined,and pure-sulfide veined orebodies.Its ores principally contain metallic minerals including pyrrhotite,pentlandite,chalcopyrite,violarite,and pyrite.Despite unidentified magma sources of ore-bearing mafic-ultramafic rocks,it is roughly accepted that the magmatic evolution in the Hongqiling deposit primarily involved fractional crystallization and crustal contamination.The ore-forming materials were primarily derived from the upper mantle,mixed with minor crustal materials.The ore-bearing mafic-ultramafic rocks in the deposit,primarily emplaced during the Indosinian(208-239 Ma),were formed in an intense extension setting followed by the collisional orogeny between the North China Plate and the Songnen-Zhangguangcai Range Block during the Middle-Late Triassic.From the perspective of the metallogenic geological setting,surrounding rocks,ore-controlling structures,and rock assemblages,this study identified one favorable condition and seven significant indicators for prospecting for Hongqiling-type nickel deposits and developed a prospecting model of the Hongqiling deposit.These serve as valuable references for exploring similar nickel deposits in the region,as well as the deep parts and margins of the Hongqiling deposit.

Optimal Power Allocation Strategy for TBLAST Based 4G Systems

There is a big demand for increasing number of subscribers in the fourth generation mobile communication systems. However, the system performance is limited by multi-path propagations and lack of efficient power allocation algorithms in conventional wireless communication systems. Optimal resource allocation and interference cancellation issues are critical for the improvement of system performance such as throughput and transmission reliability. In this paper, a turbo coded bell lab space time system (TBLAST) with optimal power allocation techniques based on eigen mode, Newton and convex optimization method and carrier-interference-and-noise ratio (CINR) are proposed to improve link reliability and to increase throughput with reasonable computational complexity. The proposed scheme is evaluated by Monte-Carlo simulations and is shown to outperform the conventional power allocation scheme.

Establishment of cell clones with different metastatic potential from the metastatic hepatocellular carcinoma cell line MHCC97

AIM: To establish clone cells with different metastatic potential for the study of metastasis-related mechanisms. METHODS: Cloning procedure was performed on parental hepatocellular carcinoma (HCC) cell line MHCC97, and biological characteristics of the target clones selected by in vivo screening were studied. RESULTS: Two clones with high (MHCC97-H) and low (MHCC97-L) metastatic potential were isolated from the parent cell line. Compared with MHCC97-L, MHCC97-H had smaller cell size (average cell diameter 43 microm vs 50 microm) and faster in vitro and in vivo growth rate (tumor cell doubling time was 34.2h vs 60.0h). The main ranges of chromosomes were 55-58 in MHCC97-H and 57-62 in MHCC97-L. Boyden chamber in vitro invasion assay demonstrated that the number of penetrating cells through the artificial basement membrane was (37.5 +/- 11.0) cells/field for MHCC97-H vs (17.7 +/- 6.3)/field for MHCC97-L. The proportions of cells in G0-G1 phase, S phase, and G2-M phase for MHCC97-H/MHCC97-L were 0.56/0.65, 0.28/0.25 and 0.16/0.10, respectively, as measured by flow cytometry. The serum AFP levels in nude mice 5wk after orthotopic implantation of tumor tissue were (246 +/- 66) microg.L(-1) for MHCC97-H and (91 +/- 66) microg.L(-1) for MHCC97-L. The pulmonary metastatic rate was 100% (10/10) vs 40% (4/10). CONCLUSION: Two clones of the same genetic background but with different biological behaviors were established, which could be valuable models for investigation on HCC metastasis.

The Role of Radiative Surface Modes and Longitudinal Excitons in the Formation of Exciton-Polariton Luminescence Spectra of CdS-Type Crystals

The low-temperature (T = 2 K) exciton-polariton luminescence (EPL) spectra in the vicinity of the exciton-resonance frequency An=1 for CdS-type crystals have been theoretically and experimentally investigated with allowance for the mechanical exciton decay . The results of the numerical calculations of the partial and interference contributions of the bulk and radiative surface spectral modes to the EPL in the geometry of additional s- and p-polarized waves emitted into vacuum are analyzed. It is shown that the contributions of purely longitudinal excitons and their interference with polaritons of the upper dispersion branch near the longitudinal frequency ωL to the EPL are small (∼10% - 30%);nevertheless, they must be taken into account to obtain quantitative agreement with experimental data. Specifically these contributions are responsible for the formation of an additional line (along with the fundamental AT line) in the case of oblique incidence of radiation.

基于B/S结构的融资信用评估系统研发

本文结合我国信用体系建设和解决企业因“信用危机”而“融资难”紧迫需要,在分析融资信用评估系统需求基础之上,结合IT技术发展趋势,提出了基于B/S结构的融资信用评估系统体系结构,建立并分析其系统功能模型、评价体系和关键技术。在此基础上,以SQLServer2000为后台数据库系统,以Java为前台开发工具,开发了一套基于EJB体系结构的融资信用评估软件原型系统。

Robust fuzzy sliding-mode control for T-S model based permanent magnet synchronous motor

A fuzzy sliding-mode control (FSMC) scheme based on T-S fuzzy models was proposed for the permanent magnet synchronous motor (PMSM) drive system to solve the speed tracking problem. A T-S fuzzy model was firstly formed to represent the nonlinear system of PMSM. For converting the tracking control into a stabilization problem, a new control design was proposed to define the internal desired states. Then, the FSMC controller for PMSM system with parameter variation and load disturbance was designed based on the fuzzy model. The performance of the proposed controller was verified by experimental results on PMSM system. The results show that the FSMC scheme can drive the dynamics of PMSM into a designated sliding surface in finite time and guarantee the property of asymptotical stability. The information of upper bound of modeling errors as well as perturbations is not required when using the FSMC controller.

基于WebGIS的城市交通信息的实时发布架构与实现

基于ArcGIS Server针对城市交通信息提供地图和实时路况的发布,首先分析了ArcGIS Server的架构,阐述了富客户端、Flex和REST的概念。对使用ArcGIS Server构建B/S结构发布方法和原理进行了说明。针对城市交通信息的发布,给出具体的发布框架和发布数据优化策略。最后以杭州市智能交通信息平台的建设为例实现交通路况的发布和实时路径网上计算。结果表明,该方法能够提供足够的GIS分析功能,并且在交互效果上明显优于以往的传统Web。

利用ASP技术实现B/S方式的抚州旅游信息系统

运用ASP技术,设计开发了抚州旅游信息系统.系统开发采用浏览器/服务器方式(B/S)结构和SQL数据库管理系统,结合相应的编程语言完成.整个系统是基于Web技术的信息发布系统,介绍了该系统的总体结构与ASP的实现技术,实现了为旅游业的管理、旅游资源开发利用与保护、宣传及政府部门决策提供有力支持的目的.

Identifying the dependency pattern of daily rainfall of Dhaka station in Bangladesh using Markov chain and logistic regression model

Bangladesh is a subtropical monsoon climate characterized by wide seasonal variations in rainfall, moderately warm temperatures, and high humidity. Rainfall is the main source of irrigation water everywhere in the Bangladesh where the inhabitants derive their income primarily from farming. Stochastic rainfall models were concerned with the occurrence of wet day and depth of rainfall for different regions to model the daily occurrence of rainfall and achieved satisfactory results around the world. In connection to the Markov chain of different order, logistic regression is conducted to visualize the dependence of current rainfall upon the rainfall of previous two-time period. It had been shown that wet day of the previous two time period compared to the dry day of previous two time period influences positively the wet day of current time period, that is the dependency of dry-wet spell for the occurrence of rain in the rainy season from April to September in the study area. Daily data are collected from meteorological department of about 26 years on rainfall of Dhaka station during the period January 1985-August 2011 to conduct the study. The test result shows that the occurrence of rainfall follows a second order Markov chain and logistic regression also tells that dry followed by dry and wet followed by wet is more likely for the rainfall of Dhaka station and also the model could perform adequately for many applications of rainfall data satisfactorily.

Electroacupuncture Alleviates Memory Deficits in APP/PS1 Mice by Targeting Serotonergic Neurons in Dorsal Raphe Nucleus

Objective Alzheimer’s disease(AD)has become a significant global concern,but effective drugs able to slow down AD progression is still lacked.Electroacupuncture(EA)has been demonstrated to ameliorate cognitive impairment in individuals with AD.However,the underlying mechanisms remains poorly understood.This study aimed at examining the neuroprotective properties of EA and its potential mechanism of action against AD.Methods APP/PS1 transgenic mice were employed to evaluate the protective effects of EA on Shenshu(BL 23)and Baihui(GV 20).Chemogenetic manipulation was used to activate or inhibit serotonergic neurons within the dorsal raphe nucleus(DRN).Learning and memory abilities were assessed by the novel object recognition and Morris water maze tests.Golgi staining,western blot,and immunostaining were utilized to determine EA-induced neuroprotection.Results EA at Shenshu(BL 23)and Baihui(GV 20)effectively ameliorated learning and memory impairments in APP/PS1 mice.EA attenuated dendritic spine loss,increased the expression levels of PSD95,synaptophysin,and brain-derived neurotrophic factor in hippocampus.Activation of serotonergic neurons within the DRN can ameliorate cognitive deficits in AD by activating glutamatergic neurons mediated by 5-HT1B.Chemogenetic inhibition of serotonergic neurons in the DRN reversed the effects of EA on synaptic plasticity and memory.Conclusion EA can alleviate cognitive dysfunction in APP/PS1 mice by activating serotonergic neurons in the DRN.Further study is necessary to better understand how the serotonergic neurons-related neural circuits involves in EA-induced memory improvement in AD.

Web Socket的远程实时监控系统设计

基于Web的远程实时监控系统,改善了基于组态软件的远程监控系统带来的监控平台异构和以数据库服务器为数据源的监控系统实时性差的缺点,实现了控制网络和信息网络之间的实时信息交换,从而使对工业现场的远程监控更具可靠性.

Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology,cognition,and behavior in APP/PS1 mice

In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial cells.However,the functional role of GGT5 in the development of Alzheimer’s disease remains unclear.This study aimed to explore the effect of GGT5 on cognitive function and brain pathology in an APP/PS1 mouse model of Alzheimer’s disease,as well as the underlying mechanism.We observed a significant reduction in GGT5 expression in two in vitro models of Alzheimer’s disease(Aβ_(1-42)-treated hCMEC/D3 and bEnd.3 cells),as well as in the APP/PS1 mouse model.Additionally,injection of APP/PS1 mice with an adeno-associated virus encoding GGT5 enhanced hippocampal synaptic plasticity and mitigated cognitive deficits.Interestingly,increasing GGT5 expression in cerebrovascular endothelial cells reduced levels of both soluble and insoluble amyloid-βin the brains of APP/PS1 mice.This effect may be attributable to inhibition of the expression ofβ-site APP cleaving enzyme 1,which is mediated by nuclear factor-kappa B.Our findings demonstrate that GGT5 expression in cerebrovascular endothelial cells is inversely associated with Alzheimer’s disease pathogenesis,and that GGT5 upregulation mitigates cognitive deficits in APP/PS1 mice.These findings suggest that GGT5 expression in cerebrovascular endothelial cells is a potential therapeutic target and biomarker for Alzheimer’s disease.

J2EE架构与MVC模式下企业内部BBS系统的设计与实现

目前企业对人力资源管理信息化过程中论坛(BBS)没有进行充分利用,针对企业内部存在的"信息孤岛"和协同设计问题,为企业内部交流设计一个内部BBS系统,将使BBS成为员工创新思想的发源地,同时企业能及时得到客户的反馈,从而提高企业的整体水平和效益。该系统基于B/S模式应用J2EE标准,采用MVC模式,其表示层、业务逻辑层、数据持久层分别采用Struts、Spring、Hibernate框架实现,在MyEclips+Mysql开发平台下进行。

Effects of rotation and gravity on an electro-magneto-thermoelastic medium with diffusion and voids by using the Lord-Shulman and dual-phase-lag models

The effects of rotation and gravity on an electro-magneto-thermoelastic medium with diffusion and voids in a generalized thermoplastic half-space are studied by using the Lord-Shulman (L-S) model and the dual-phase-lag (DPL) model. The analytical solutions for the displacements, stresses, temperature, diffusion concentration, and volume fraction field with different values of the magnetic field, the rotation, the gravity, and the initial stress are obtained and portrayed graphically. The results indicate that the effects of gravity, rotation, voids, diffusion, initial stress, and electromagnetic field are very pronounced on the physical properties of the material.

基于B/S和SOA架构的LIMS系统设计与研究

为提升水质检测业务的专业化、智能化、系统化、自动化水平,针对新发展阶段下水利高质量发展对水质信息管理的需求,研究并开发基于B/S系统架构和SOA设计架构的新型综合性水质信息管理系统(LIMS),运用仪器谱图识别及数据提取、PHP与MySQL融合、仪器谱图与原始记录自动关联等技术,在一定程度上提高水质数据的电子化无纸化获取、处理、传输及应用等方面的管理水平,实现水质检测业务流程与资源的动态关联和闭环追溯,提升水质监测评价工作的管理效率和质量管理能力。基于B/S和SOA架构的LIMS在前沿高新技术中的应用研究,为水质检测和管理的各项活动提供智能、高效的数据支持平台,也为水利行业信息系统管理建设及水域功能监测监管提供技术支撑。

Bone marrow-derived mesenchymal stem cell transplantation attenuates overexpression of inflammatory mediators in rat brain after cardiopulmonary resuscitation

Emerging evidence suggests that bone marrow-derived mesenchymal stem cell transplantation improves neurological function after cardiac arrest and cardiopulmonary resuscitation;however, the precise mechanisms remain unclear. This study aimed to investigate the effect of bone marrow-derived mesenchymal stem cell treatment on expression profiles of multiple cytokines in the brain after cardiac arrest and cardiopulmonary resuscitation. Cardiac arrest was induced in rats by asphyxia and cardiopulmonary resuscitation was initiated 6 minutes after cardiac arrest. One hour after successful cardiopulmonary resuscitation, rats were injected with either phosphate-buffered saline(control) or 1 × 10~6 bone marrow-derived mesenchymal stem cells via the tail vein. Serum S100 B levels were measured by enzyme-linked immunosorbent assay and neurological deficit scores were evaluated to assess brain damage at 3 days after cardiopulmonary resuscitation. Serum S100 B levels were remarkably decreased and neurological deficit scores were obviously improved in the mesenchymal stem cell group compared with the phosphate-buffered saline group. Brains were isolated from the rats and expression levels of 90 proteins were determined using a RayBio Rat Antibody Array, to investigate the cytokine profiles. Brain levels of the inflammatory mediators tumor necrosis factor-α, interferon-γ, macrophage inflammatory protein-1α, macrophage inflammatory protein-2, macrophage inflammatory protein-3α, macrophage-derived chemokine, and matrix metalloproteinase-2 were decreased ≥ 1.5-fold, while levels of the anti-inflammatory factor interleukin-10 were increased ≥ 1.5-fold in the mesenchymal stem cell group compared with the control group. Donor mesenchymal stem cells were detected by immunofluorescence to determine their distribution in the damaged brain, and were primarily observed in the cerebral cortex. These results indicate that bone marrow-derived mesenchymal stem cell transplantation attenuates brain damage induced by cardiac arrest and cardiopulmonary resuscitation, possibly via regulation of inflammatory mediators. This experimental protocol was approved by the Institutional Animal Care and Use Committee of Fujian Medical University, China in January 2016(approval No. 2016079).

基于C/S+B/S混合模式的网络考试系统原型分析及实现

随着高校学生人数的增加,教学内容日益增多且不断更新,考试与考核工作变得非常繁重。为了推动考试方法改革,加快考核手段的现代化,根据教学的实际需求,我们以工程化的软件开发模式,以UML为建模语言,使用ModelMaker这个CASE工具,分析、设计开发成功了一个基于COM+和XML的分布式的多层混合模型的网络考试系统。本文将详细向您介绍网络考试系统的原型及实现方法。

基于B/S模式的网络版实验室管理系统

实践教学是培养学生创新精神、实践能力和科学素质的重要途径,而实验室则是实践教学的主战场.如何充分发挥实验室作用,提高实验室利用率就显得尤为重要.大学校园网日臻完善,通过开发和使用基于互联网B S模式的实验室信息管理系统,实现实验室的网络化管理,实现实验室信息资源的时效性、开放性、共享性.

胎膜早破宫内感染产妇脐血和羊水中miR-182、TNF-α、S100B预测早产儿脑损伤价值

目的:探究胎膜早破宫内感染产妇脐血和羊水中微小核糖核酸182(miR-182)、肿瘤坏死因子-α(TNF-α)及S100钙结合蛋白B(S100B)预测早产儿脑损伤的临床价值。方法:选取2021年6月-2023年6月在本院分娩的104例胎膜早破宫内感染产妇临床资料,分娩的早产儿胎龄均<34周,行头部影像学检查,根据是否发生脑损伤将产妇分为脑损伤组(n=36)与非脑脑损伤组(n=68)。检测并比较两组脐血和羊水中miR-182、TNF-α、S100B蛋白水平,采用受试者工作特征(ROC)曲线评价胎膜早破宫内感染产妇脐血和羊水miR-182、TNF-α及S100B蛋白对早产儿脑损伤的预测价值。结果:脑损伤组脐血miR-182、TNF-α、S100B蛋白水平均高于非脑损伤组,羊水miR-182、TNF-α均高于非脑损伤组(均P<0.05),羊水中S100B蛋白水平两组无差异(P>0.05)。ROC曲线分析,脐血miR-182、TNF-α、S100B蛋白预测早产儿脑损伤的曲线下面积(AUC)分别为0.816、0.748、0.697,灵敏度分别为72.2%、66.7%、55.6%,特异度分别为83.8%、77.9%、88.2%;羊水miR-182、TNF-α、S100B蛋白预测早产儿脑损伤的AUC分别为0.713、0.689、0.594,灵敏度分别为63.9%、55.6%、30.6%,特异度分别为86.8%、85.3%、86.8%。结论:胎膜早破宫内感染产妇脐血和羊水中miR-182、TNF-α、S100B蛋白预测其早产儿脑损伤均有一定价值。