四因融一的诗学品质和两因兼备的创作方法——论易卜生的戏剧诗学特质及其渊源

易卜生戏剧的独特品质与魅力是由“现实精神、哲学睿智、宗教尺度、诗想神思”四因融一的诗学品质和“再现\表现”两因兼备的创作方法所达成,这使其创作具有了超越狭隘流派之上的万脉归一、众美兼备、高标孤峙的大师品质与现代品质。其形成则根源于个人经历、民族历史、地域环境和文化渊源及戏剧诗学传统的影响,在欧洲戏剧诗学理念的嬗变中,完成了由古希腊的人神(自然)对峙的大宇宙悲剧观(宇宙——自由)、莎士比亚代表的近代的人我互争的小宇宙悲剧观(社会——欲望)向现代的人性分裂的人类学悲剧观(人——本质)的嬗变,这既是一次综合,又是一次飞跃。因而具有极其重大的美学意义。

CT仿真血管镜对动脉硬化症诊断价值的探讨

目的:探讨CT仿真血管镜对动脉硬化症的诊断价值。方法:31例动脉硬化症患者及30例正常人行多层螺旋CT扫描,将所有的CT图像进行低对比薄层重建,然后将重建图像导入CT3D工作站,用软件CT仿真内窥镜、多平面成像、最大密度投影、容积成像技术进行图像后处理,并就正常血管及病变血管在CT仿真血管镜中的改变进行分析和记录。结果:61例均成功地进行了CT仿真血管镜成像,31例动脉硬化症患者病变血管中,血管壁钙化29例88处,血管内壁不规则及增厚28例,血管狭窄28例,动脉硬化斑块17例56处;正常人组的仿真血管镜图像为血管壁光滑,管腔无狭窄。12例动脉硬化患者行血管造影术,检查结果与CT仿真血管镜成像相似。结论:多层螺旋CT仿真血管镜可以作为诊断动脉硬化症的一种无创技术。

粘着斑激酶在大鼠组织及血管再狭窄和动脉粥样硬化血管中的表达

目的 研究粘着斑激酶在不同年龄大鼠各组织中的分布以及在血管再狭窄和动脉粥样硬化血管中的表达。方法 应用Westernblot技术研究粘着斑激酶在不同年龄大鼠各组织中的分布以及在血管内皮剥脱术后再狭窄和动脉粥样硬化血管中的表达。结果 粘着斑激酶在1月龄幼年大鼠各组织中的表达较成年大鼠明显升高;在血管内皮剥脱术后3,7,14天粘着斑激酶表达逐渐升高,2 1天有所下降,但仍高于对照组;粘着斑激酶在动脉粥样硬化血管中的表达较对照组升高。结论 粘着斑激酶可能参与胚胎发育后各组织的发育调节;粘着斑激酶可能参与血管成形术后再狭窄及动脉硬化的病理过程,粘着斑激酶表达的上调可能在血管成形术后再狭窄及动脉硬化的发病过程中起重要作用。

心身放松疗法对脑动脉硬化症患者负性情绪及A型行为的影响

目的评估心身放松疗法治疗脑动脉硬化患者临床疗效。方法将60例脑动脉硬化患者随机分为实验组(心身放松疗法加常规治疗)和对照组(常规治疗),疗程均为8周,使用躯体症状量表、焦虑自评量表(SAS)、抑郁自评量表(SDS)及A型行为量表评估两组的临床疗效。结果与治疗前和对照组比较,实验组在治疗8周后其躯体症状(11.60±6.58)、SAS(39.63±7.73)、SDS(42.53±7.83)评分及A型行为总分与因子分均明显下降,差异具有显著性(P<0.05或P<0.01);而对照组除躯体症状量表记分较治疗前显著性降低外(P<0.05),其他量表评分治疗前后均无显著性变化(P>0.05)。结论心身放松疗法具有改善脑动脉硬化患者躯体症状、焦虑抑郁情绪和降低A型行为评分的作用。

动脉粥样硬化相关性疾病血清胆红素与血脂检测结果分析

目的:探讨血清胆红素浓度与四种动脉粥样硬化( AS)性疾病的关系。方法:观察组分为四组,单纯性高血压组、冠心病组、糖尿病组、脑梗死组,对照组为同年龄段健康查体者,检测空腹血清总胆红素、直接胆红素、总胆固醇、三酰甘油、高密度脂蛋白胆固醇,低密度脂蛋白胆固醇,计算间接胆红素,并对检测结果进行统计学分析。结果:与对照组比较,观察组中直接胆红素均有所下降,但差异无显著统计学意义( P>0 .0 5 ) ,总胆红素与间接胆红素除脑梗死组外,其他各组均明显降低( P<0 .0 5 ) ;除脑梗死组HDL - C与对照组无显著差异外,其他观察组血脂各指标与对照组比较均有显著统计学差异( P<0 .0 5 ) ,且糖尿病组三酰甘油及冠心病组低密度脂蛋白胆固醇与对照组比较有极显著统计学差异( P<0 .0 1 )。结论:高血压、冠心病、脑梗死、糖尿病等动脉粥样硬化相关性疾病血清胆红素浓度有不同程度降低,其中,间接胆红素降低更明显。

From Innocence to Suffering to Awareness:Nada Confrontation in Francis Macomber

The Short Happy Life of Francis Macomber is a quintessential Hemingway tale of one man's attempt to overcome an in ternal struggle by mastering the external world. Francis Macomber discovers his own bravery and strength when he ignores his self-consciousness and relies on instinct. This essay will examine Hemingway's code and how it confronts nada thus analyze Macomber's change from innocent to suffering to aware.

Application of buried auricular point combined with Wenjing Sanhan prescription in arteriosclerosis obliterans patients with resting pain

BACKGROUND Research on the combined use of ear acupoint embedding beans and warming meridians with cold-dispersing formulas for alleviating resting pain in patients with arteriosclerosis obliterans(ASO)remains limited.AIM To explore the therapeutic efficacy of auricular point embedding beans combined with Wenjing Sanhan prescription in alleviating resting pain in patients with lower-limb ASO.METHODS A total of 100 patients with ASO experiencing resting pain who were treated at our hospital from January 2022 to January 2023 were enrolled.They were randomly allocated into two groups using a double-blind approach.The control group was treated using a warming meridian with a cold-dispersing formula,while the study group received additional treatment with ear acupoint embedding beans.The clinical efficacy,ankle-brachial artery pressure ratio,hemorheological indicators,and traditional Chinese medicine symptom scores were compared between the two groups.RESULTS The clinical efficacy rate in the study group was significantly higher(94.00%)than that in the control group(72.00%,P<0.05).Moreover,the ankle-brachial artery pressure ratio was significantly higher in the study group after treatment(P<0.05).Hemorheological parameters,including whole blood viscosity,plasma viscosity(1.83±0.11)mPa/s,fibrinogen levels(3.30±0.21)g/L,platelet adhesion rate(49.87%±10.51%),and erythrocyte aggregation index(1.79±0)were improved in the study group compared to the control group.In addition,the scores for decreased skin temperature(1.41±0.26),intermittent claudication(1.30±0.20),and resting pain(1.23±0.31)were significantly lower in the study group than those in the control group(all P<0.05).The level of oxidative stress in the study group also exhibited significant improvement(P<0.05),and the levels of inflammatory factors were considerably lower than those in the control group.CONCLUSION The combination of ear point embedding beans and Wenjing Sanhan prescription demonstrates promising clinical efficacy in alleviating resting pain associated with ASO.

老年人糖耐量异常与动脉粥样硬化

目的:探讨老年人糖耐量异常(IGT)与动脉粥样硬化的关系。方法:在60岁以上的人群中筛查,按照75g葡萄糖耐量试验将研究对象分为糖尿病(DM)组、IGT组和正常糖耐量(NGT)组。抽血检查血脂及胰岛素水平,B型超声检查双侧颈总动脉内中膜厚度(IMT)。结果:IGT组的IMT值和内膜连续性比NGT组差;DM组胆固醇(CH)、甘油三酯(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)及空腹胰岛素(FINS)水平均比NGT组高;以上指标IGT组与DM组差别无统计学意义。logistic回归分析表明:年龄、CH、TG、HDL、LDL水平与IGT相关。结论:与NGT组相比,IGT组存在明显的动脉粥样硬化表现,其程度与糖尿病患者接近。IGT参与动脉粥样硬化的形成。

脑梗死与颈动脉粥样斑块的相关性分析

目的探讨脑梗死与颈动脉粥样硬化斑块的相关性。方法采用彩色多普勒血流成像技术对217例脑梗死患者进行检测,观察其梗死侧和非梗死侧颈动脉内中膜厚度、斑块的部位、大小及其数目、动脉狭窄程度以及血流动力学改变等,并与124例对照组颈动脉粥样硬化斑块检出情况进行比较。结果脑梗死组患者的颈动脉粥样硬化斑块检出率为72.8%,显著高于对照组(25%,P<0.01)。颈动脉粥样硬化斑块多发生在脑梗死病灶的同侧,占85%,以颈总动脉分叉处居多,占58.4%。多因素Logistic回归分析显示斑块大小及其数量、峰值流速、搏动指数与脑梗死有明显的相关性(P<0.05),而颈动脉内中膜厚度、狭窄程度无明显差异(P>0.05)。结论脑梗死的发生与颈动脉粥样硬化斑块密切相关,防止斑块的形成对防止脑梗死的发生有非常重要的意义。

Transcription profiles of skin and head kidney from goldfish suffering hemorrhagic septicemia with an emphasis on the TLR signaling pathway

DEAR EDITOR, Hemorrhagic septicemia is an acute, highly fatal disease that affects goldfish (Carassius auratus). To gain a better understanding of related immune genes, the transcriptomes of the skin and head kidney of goldfish suffering hemorrhagic septicemia were sequeneed, assembled, and characterized.

Th17/Treg balance and macrophage polarization ratio in lower extremity arteriosclerosis obliterans

Objective:To explore the balance of peripheral blood T helper 17 cells/regulatory T cell(Th17/Treg)ratio and the polarization ratio of M1 and M2 macrophages in lower extremity arteriosclerosis obliterans(ASO).Methods:A rat model of lower extremity ASO was established,and blood samples from patients with lower extremity ASO before and after surgery were obtained.ELISA was used to detect interleukin 6(IL-6),IL-10,and IL-17.Real-time RCR and Western blot analyses were used to detect Foxp3,IL-6,IL-10,and IL-17 expression.Moreover,flow cytometry was applied to detect the Th17/Treg ratio and M1/M2 ratio.Results:Compared with the control group,the iliac artery wall of ASO rats showed significant hyperplasia,and the concentrations of cholesterol and triglyceride were significantly increased(P<0.01),indicating the successful establishment of ASO.Moreover,the levels of IL-6 and IL-17 in ASO rats were pronouncedly increased(P<0.05),while the IL-10 level was significantly decreased(P<0.05).In addition to increased IL-6 and IL-17 levels,the mRNA and protein levels of Foxp3 and IL-10 in ASO rats were significantly decreased compared with the control group.The Th17/Treg and M1/M2 ratios in the ASO group were markedly increased(P<0.05).These alternations were also observed in ASO patients.After endovascular surgery(such as percutaneous transluminal angioplasty and arterial stenting),all these changes were significantly improved(P<0.05).Conclusions:The Th17/Treg and M1/M2 ratios were significantly increased in ASO,and surgery can effectively improve the balance of Th17/Treg,and reduce the ratio of M1/M2,and the expression of inflammatory factors.

肝细胞生长因子与冠状动脉狭窄程度的相关性研究

目的:探讨肝细胞生长因子(HGF)、血管内皮生长因子(VEGF)、肿瘤坏死因子-α(TNF-α)与冠心病病变程度的相关性。方法:63例冠心病患者根据冠状动脉狭窄程度分为3组:轻度组18例,中度组22例,重度组23例,采用酶联免疫吸附法检测外周血HGF、VEGF、TNF-α水平,与20例年龄和性别相当的健康者(对照组)进行比较。冠心病患者按心绞痛分级Ⅰ级12例,Ⅱ级14例,Ⅲ级15例,Ⅳ级22例,与HGF、VEGF、TNF-α水平进行相关分析。结果:血清HGF水平重度组、中度组及轻度组明显高于对照组,有极显著性差异(P<0.01);血清VEGF、TNF-α水平重度组、中度组均明显高于轻度组及对照组,有极显著性差异(P<0.01);HGF、VEGF、TNF-α水平与心绞痛分级呈正相关(r1=0.864P<0.01;r2=0.682P<0.01;r3=0.403P<0.01)。结论:HGF、VEGF、TNF-α与心绞痛程度呈显著正相关,其中HGF较其他两项指标相关性更好。

历史的“遗漏”:深入杨逵文学精神

“压不扁的玫瑰花”精神是人们对台湾著名作家杨逵精神品格的根本认同,也是人们解读其文学价值的不二视角,但这一认识却在很大程度上遮蔽了杨逵文学精神在深层次上承续着的中华民族深厚的传统文化精神及其与生俱来的忧患意识,以及在“五四”新文化运动中建构起的人道主义理性原则。于世界融通,民族统一呼声日隆的今天,重新深入杨逵文学精神,无疑会获得更为深刻的现实启迪。

盐酸丁咯地尔治疗脑动脉硬化记忆障碍研究

目的研究盐酸丁咯地尔治疗对脑动脉硬化记忆障碍患者记忆功能、脑血流量、脑电图等的影响。方法脑动脉硬化记忆障碍患者76例,随机分为研究组(42例)和对照组(34例),分别给予盐酸丁咯地尔0.1g与胞二磷胆碱0.5g静脉滴注,每日1次共8周。治疗前后记忆测定及经颅多谱勒、脑电图检查。结果研究组即刻记忆和临床全面记忆能力较对照组明显改善(P<0.01);盐酸丁咯地尔治疗后患者脑血流指标、脑电图改善亦较对照组显著(P<0.05～0.01)。结论盐酸丁咯地尔治疗可提高脑动脉硬化记忆障碍患者的脑血流量,改善脑电图从而改善患者的记忆能力。

ACUPUNCTURE TREATMENT OF 60 CASES OF NUMBNESS DUE TO CEREBRAL ARTERIOSCLEROSIS

Numbness is one of the chief symptoms ofcerebral arteriosclerosis.The author treated 60cases of the disease satisfactorily and reports theresults as follows.CLINICAL MATERALSOf the 60 patients,39 were males and 21females.The age distribution was for 30

Clinical and prognostic features in asymptomatic and symptomatic patients with arteriosclerosis obliterans

Background: Patients with arteriosclerosis obliterans (ASO) often have co-existing atherosclerotic diseases. The purpose of this study was to examine the clinical features of patients with ASO, including the overlap of atherosclerotic risk factors, characteristics of car-diovascular events, and clinical prognosis. Method: We enrolled 205 consecutive patients who had ankle brachial index (ABI) of ?0.9 between January 2008 and December 2009. Fontaine (F) classification and clinical background were evaluated and clinical events including mortality and major adverse cardiocerebro-vascular events (MACCEs) were determined. Results: There was a high prevalence of each risk factor. Sixty- five percent of subjects had three or more of the four overlapping risk factors, including hypertension, dia- betes, dyslipidemia, and smoking. After a maximum follow-up of 800 days, the incidence of MACCEs and mortality was 46% and 10%, respectively. We divided the patients into two groups according to the presence of ASO symptoms (F1 and F2-4) and compared the incidence of events. The incidence of MACCEs and mortality in the F2-4 group was significantly higher than that in the F1 group (P = 0.048, P = 0.044, respectively). After excluding lower extremity revascularization, coronary artery disease was a common cause of MACCEs, and the mortality rates after MACCEs increased in a stepwise manner according to F classification severity (P = 0.028). Conclusion: Patients with ASO had overlapping coronary risk factors and a high incidence rate of cardiovascular events. The incidence of coronary events was common, especially in symptomatic patients, and the mortality rates after MACCEs were high in accordance with F classification severity.

Marie's Suffering in A Road to the Big City from the Perspective of Feminism

Some scholars concerns about the conflicts between Marie and Lilla, but few of them studies the conflicts between femaleand male in the novel. In the novel, Marie's suffering is not only from the fraudulence of her sister, but also from the oppression ofmale by the perspective of feminism.In the family, it implies that she is oppressed by male, which can be understood from the differ-ence of their jobs and the traditional image of her mother, while in the society, she suffers a lot from Jansen, which can be seen fromthe descriptive perspective of appearance of Marie, the dialogue between waitress and Jansen, the dialogue between Marie and Jan-sen as well as Jansen's decision to the leaving of Marie. The double oppression of Marie's suffering both reflects the unequal posi-tion of male and female.By this analysis, it can impulse female to improve themselves and it also calls on female to get along wellwith male by the appropriate way.

Advances in the management of arteriosclerosis of the lower extremity:Integrating Western and Chinese medicine approaches

This editorial provides a commentary on the recent article.The paper reviews current literature and explores innovative treatment strategies for lower extremity arteriosclerosis obliterans(LEASO)through an integrative approach.It highlights the effectiveness of combination therapies that merge traditional Chinese medicine(TCM)with Western medical practices,suggesting that such integrative methods may improve patient compliance and outcomes through personalized care.This paper stresses the importance of rigorous clinical trials to evaluate the efficacy and safety of TCM interventions within LEASO treatment protocols,advocating for evidence-based validation of these combined therapies.Our recommendations emphasize accurate diagnosis,appropriate pharmacological in-terventions,the use of advanced surgical and endovascular techniques,and the inclusion of TCM to address underlying dysfunctions.Additionally,continuous monitoring,patient education,and lifestyle modifications are essential to slow disease progression and achieve optimal patient outcomes.The paper concludes by calling for further research to develop standardized treatment protocols that effectively integrate both Western and Chinese medical approaches in managing LEASO.

二维及彩色多普勒超声在椎动脉粥样硬化病变中的应用

目的探讨二维及彩色多普勒超声在椎动脉粥样硬化病变中的应用价值。方法本组对76例糖尿病、高血压、脑梗死、高血脂等血管疾病多发人群,进行双侧椎动脉二维及彩色多普勒超声检查,观察椎动脉内径、内膜、走行、管腔内血流情况,并进行血流动力学检测。结果根据所测内径、内膜和斑块等图像特征和血流动力学改变,可以反映椎动脉硬化及狭窄等情况。结论超声对诊断椎动脉粥样硬化,椎基底动脉供血不足有一定的临床实用价值。

脑导纳微分环流入相面积值的探讨

目的:本项研究的目的是探讨脑导纳微分环快流入相和慢流入相面积和对血管弹性判定的诊断价值。方法:应用深圳市辉大高科技发展有限公司研制和生产的HD-ENG导纳式双侧脑血流图自动检测仪对高血压患者进行脑导纳环检测,并与正常组比较。结果:研究结果显示高血压病患者的脑导纳微分环的流入相的面积与正常组有显著性差异;而高血压有动脉硬化和无动脉硬化患者之间却不存在显著性差异。