This paper presents a binary gravitational search algorithm (BGSA) is applied to solve the problem of optimal allotment of DG sets and Shunt capacitors in radial distribution systems. The problem is formulated as a no...This paper presents a binary gravitational search algorithm (BGSA) is applied to solve the problem of optimal allotment of DG sets and Shunt capacitors in radial distribution systems. The problem is formulated as a nonlinear constrained single-objective optimization problem where the total line loss (TLL) and the total voltage deviations (TVD) are to be minimized separately by incorporating optimal placement of DG units and shunt capacitors with constraints which include limits on voltage, sizes of installed capacitors and DG. This BGSA is applied on the balanced IEEE 10 Bus distribution network and the results are compared with conventional binary particle swarm optimization.展开更多
Two new regularization algorithms for solving the first-kind Volterra integral equation, which describes the pressure-rate deconvolution problem in well test data interpretation, are developed in this paper. The main ...Two new regularization algorithms for solving the first-kind Volterra integral equation, which describes the pressure-rate deconvolution problem in well test data interpretation, are developed in this paper. The main features of the problem are the strong nonuniform scale of the solution and large errors (up to 15%) in the input data. In both algorithms, the solution is represented as decomposition on special basic functions, which satisfy given a priori information on solution, and this idea allow us significantly to improve the quality of approximate solution and simplify solving the minimization problem. The theoretical details of the algorithms, as well as the results of numerical experiments for proving robustness of the algorithms, are presented.展开更多
Numerous cryptographic algorithms (ElGamal, Rabin, RSA, NTRU etc) require multiple computations of modulo multiplicative inverses. This paper describes and validates a new algorithm, called the Enhanced Euclid Algorit...Numerous cryptographic algorithms (ElGamal, Rabin, RSA, NTRU etc) require multiple computations of modulo multiplicative inverses. This paper describes and validates a new algorithm, called the Enhanced Euclid Algorithm, for modular multiplicative inverse (MMI). Analysis of the proposed algorithm shows that it is more efficient than the Extended Euclid algorithm (XEA). In addition, if a MMI does not exist, then it is not necessary to use the Backtracking procedure in the proposed algorithm;this case requires fewer operations on every step (divisions, multiplications, additions, assignments and push operations on stack), than the XEA. Overall, XEA uses more multiplications, additions, assignments and twice as many variables than the proposed algorithm.展开更多
The contradiction of variable step size least mean square(LMS)algorithm between fast convergence speed and small steady-state error has always existed.So,a new algorithm based on the combination of logarithmic and sym...The contradiction of variable step size least mean square(LMS)algorithm between fast convergence speed and small steady-state error has always existed.So,a new algorithm based on the combination of logarithmic and symbolic function and step size factor is proposed.It establishes a new updating method of step factor that is related to step factor and error signal.This work makes an analysis from 3 aspects:theoretical analysis,theoretical verification and specific experiments.The experimental results show that the proposed algorithm is superior to other variable step size algorithms in convergence speed and steady-state error.展开更多
This work proposes a novel approach for multi-type optimal placement of flexible AC transmission system(FACTS) devices so as to optimize multi-objective voltage stability problem. The current study discusses a way for...This work proposes a novel approach for multi-type optimal placement of flexible AC transmission system(FACTS) devices so as to optimize multi-objective voltage stability problem. The current study discusses a way for locating and setting of thyristor controlled series capacitor(TCSC) and static var compensator(SVC) using the multi-objective optimization approach named strength pareto multi-objective evolutionary algorithm(SPMOEA). Maximization of the static voltage stability margin(SVSM) and minimizations of real power losses(RPL) and load voltage deviation(LVD) are taken as the goals or three objective functions, when optimally locating multi-type FACTS devices. The performance and effectiveness of the proposed approach has been validated by the simulation results of the IEEE 30-bus and IEEE 118-bus test systems. The proposed approach is compared with non-dominated sorting particle swarm optimization(NSPSO) algorithm. This comparison confirms the usefulness of the multi-objective proposed technique that makes it promising for determination of combinatorial problems of FACTS devices location and setting in large scale power systems.展开更多
In this paper we consider a parallel algorithm that detects the maximizer of unimodal function f(x) computable at every point on unbounded interval (0, ∞). The algorithm consists of two modes: scanning and detecting....In this paper we consider a parallel algorithm that detects the maximizer of unimodal function f(x) computable at every point on unbounded interval (0, ∞). The algorithm consists of two modes: scanning and detecting. Search diagrams are introduced as a way to describe parallel searching algorithms on unbounded intervals. Dynamic programming equations, combined with a series of liner programming problems, describe relations between results for every pair of successive evaluations of function f in parallel. Properties of optimal search strategies are derived from these equations. The worst-case complexity analysis shows that, if the maximizer is located on a priori unknown interval (n-1], then it can be detected after cp(n)=「2log「p/2」+1(n+1)」-1 parallel evaluations of f(x), where p is the number of processors.展开更多
AIM To examine the practice pattern in Kaiser Permanente Southern California(KPSC), i.e., gastroenterology(GI)/surgery referrals and endoscopic ultrasound(EUS), for pancreatic cystic neoplasms(PCNs) after the regionwi...AIM To examine the practice pattern in Kaiser Permanente Southern California(KPSC), i.e., gastroenterology(GI)/surgery referrals and endoscopic ultrasound(EUS), for pancreatic cystic neoplasms(PCNs) after the regionwide dissemination of the PCN management algorithm.METHODS Retrospective review was performed; patients with PCN diagnosis given between April 2012 and April 2015(18 mo before and after the publication of the algorithm) in KPSC(integrated health system with 15 hospitals and 202 medical offices in Southern California) were identified.RESULTS2558(1157 pre-and 1401 post-algorithm) received a new diagnosis of PCN in the study period. There was no difference in the mean cyst size(pre-19.1 mm vs post-18.5 mm, P = 0.119). A smaller percentage of PCNs resulted in EUS after the implementation of the algorithm(pre-45.5% vs post-34.8%, P < 0.001). A smaller proportion of patients were referred for GI(pre-65.2% vs post-53.3%, P < 0.001) and surgery consultations(pre-24.8% vs post-16%, P < 0.001) for PCN after the implementation. There was no significant change in operations for PCNs. Cost of diagnostic care was reduced after the implementation by 24%, 18%, and 36% for EUS, GI, and surgery consultations, respectively, with total cost saving of 24%.CONCLUSION In the current healthcare climate, there is increased need to optimize resource utilization. Dissemination of an algorithm for PCN management in an integrated health system resulted in fewer EUS and GI/surgery referrals, likely by aiding the physicians ordering imaging studies in the decision making for the management of PCNs. This translated to cost saving of 24%, 18%, and 36% for EUS, GI, and surgical consultations, respectively, with total diagnostic cost saving of 24%.展开更多
In biology, signal transduction refers to a process by which a cell converts one kind of signal or stimulus into another. It involves ordered sequences of biochemical reactions inside the cell. These cascades of react...In biology, signal transduction refers to a process by which a cell converts one kind of signal or stimulus into another. It involves ordered sequences of biochemical reactions inside the cell. These cascades of reactions are carried out by enzymes and activated by second messengers. Signal transduction pathways are complex in nature. Each pathway is responsible for tuning one or more biological functions in the intracellular environment as well as more than one pathway interact among themselves to carry forward a single biological function. Such kind of behavior of these pathways makes understanding difficult. Hence, for the sake of simplicity, they need to be partitioned into smaller modules and then analyzed. We took VEGF signaling pathway, which is responsible for angiogenesis for this kind of modularized study. Modules were obtained by applying the algorithm of Nayak and De (Nayak and De, 2007) for different complexity values. These sets of modules were compared among themselves to get the best set of modules for an optimal complexity value. The best set of modules compared with four different partitioning algorithms namely, Farhat’s (Farhat, 1998), Greedy (Chartrand and Oellermann, 1993), Kernighan-Lin’s (Kernighan and Lin, 1970) and Newman’s community finding algorithm (Newman, 2006). These comparisons enabled us to decide which of the aforementioned algorithms was the best one to create partitions from human VEGF signaling pathway. The optimal complexity value, on which the best set of modules was obtained, was used to get modules from different species for comparative study. Comparison among these modules would shed light on the trend of development of VEGF signaling pathway over these species.展开更多
In this study,our aim is to address the problem of gene selection by proposing a hybrid bio-inspired evolutionary algorithm that combines Grey Wolf Optimization(GWO)with Harris Hawks Optimization(HHO)for feature selec...In this study,our aim is to address the problem of gene selection by proposing a hybrid bio-inspired evolutionary algorithm that combines Grey Wolf Optimization(GWO)with Harris Hawks Optimization(HHO)for feature selection.Themotivation for utilizingGWOandHHOstems fromtheir bio-inspired nature and their demonstrated success in optimization problems.We aimto leverage the strengths of these algorithms to enhance the effectiveness of feature selection in microarray-based cancer classification.We selected leave-one-out cross-validation(LOOCV)to evaluate the performance of both two widely used classifiers,k-nearest neighbors(KNN)and support vector machine(SVM),on high-dimensional cancer microarray data.The proposed method is extensively tested on six publicly available cancer microarray datasets,and a comprehensive comparison with recently published methods is conducted.Our hybrid algorithm demonstrates its effectiveness in improving classification performance,Surpassing alternative approaches in terms of precision.The outcomes confirm the capability of our method to substantially improve both the precision and efficiency of cancer classification,thereby advancing the development ofmore efficient treatment strategies.The proposed hybridmethod offers a promising solution to the gene selection problem in microarray-based cancer classification.It improves the accuracy and efficiency of cancer diagnosis and treatment,and its superior performance compared to other methods highlights its potential applicability in realworld cancer classification tasks.By harnessing the complementary search mechanisms of GWO and HHO,we leverage their bio-inspired behavior to identify informative genes relevant to cancer diagnosis and treatment.展开更多
In this paper, a new class of over-relaxed proximal point algorithms for solving nonlinear operator equations with (A,η,m)-monotonicity framework in Hilbert spaces is introduced and studied. Further, by using the gen...In this paper, a new class of over-relaxed proximal point algorithms for solving nonlinear operator equations with (A,η,m)-monotonicity framework in Hilbert spaces is introduced and studied. Further, by using the generalized resolvent operator technique associated with the (A,η,m)-monotone operators, the approximation solvability of the operator equation problems and the convergence of iterative sequences generated by the algorithm are discussed. Our results improve and generalize the corresponding results in the literature.展开更多
In this paper, the application of modified genetic algorithms (MGA) in the optimization of the ARX Model-based observer of the Pneumatic Artificial Muscle (PAM) manipulator is investigated. The new MGA algorithm is pr...In this paper, the application of modified genetic algorithms (MGA) in the optimization of the ARX Model-based observer of the Pneumatic Artificial Muscle (PAM) manipulator is investigated. The new MGA algorithm is proposed from the genetic algorithm with important additional strategies, and consequently yields a faster convergence and a more accurate search. Firstly, MGA-based identification method is used to identify the parameters of the nonlinear PAM manipulator described by an ARX model in the presence of white noise and this result will be validated by MGA and compared with the simple genetic algorithm (GA) and LMS (Least mean-squares) method. Secondly, the intrinsic features of the hysteresis as well as other nonlinear disturbances existing intuitively in the PAM system are estimated online by a Modified Recursive Least Square (MRLS) method in identification experiment. Finally, a highly efficient self-tuning control algorithm Minimum Variance Control (MVC) is taken for tracking the joint angle position trajectory of this PAM manipulator. Experiment results are included to demonstrate the excellent performance of the MGA algorithm in the NARX model-based MVC control system of the PAM system. These results can be applied to model, identify and control other highly nonlinear systems as well.展开更多
In certain computational systems the amount of space required to execute an algorithm is even more restrictive than the corresponding time necessary for solution of a problem. In this paper an algorithm for modular mu...In certain computational systems the amount of space required to execute an algorithm is even more restrictive than the corresponding time necessary for solution of a problem. In this paper an algorithm for modular multiplicative inverse is introduced and its computational space complexity is analyzed. A tight upper bound for bit storage required for execution of the algorithm is provided. It is demonstrated that for range of numbers used in public-key encryption systems, the size of bit storage does not exceed a 2K-bit threshold in the worst-case. This feature of the Enhanced-Euclid algorithm allows designing special-purpose hardware for its implementation as a subroutine in communication-secure wireless devices.展开更多
The VRP is classified as an NP-hard problem. Hence exact optimization methods may be difficult to solve these problems in acceptable CPU times, when the problem involves real-world data sets that are very large. To ge...The VRP is classified as an NP-hard problem. Hence exact optimization methods may be difficult to solve these problems in acceptable CPU times, when the problem involves real-world data sets that are very large. To get solutions in determining routes which are realistic and very close to the actual solution, we use heuristics and metaheuristics which are of the combinatorial optimization type. A literature review of VRPTW, TDVRP, and a metaheuristic such as the genetic algorithm was conducted. In this paper, the implementation of the VRPTW and its extension, the time-dependent VRPTW (TDVRPTW) has been carried out using the model as well as metaheuristics such as the genetic algorithm (GA). The algorithms were implemented, using Matlab and HeuristicLab optimization software. A plugin was developed using Visual C# and DOT NET framework 4.5. Results were tested using Solomon’s 56 benchmark instances classified into groups such as C1, C2, R1, R2, RC1, RC2, with 100 customer nodes, 25 vehicles and each vehicle capacity of 200. The results were comparable to the earlier algorithms developed and in some cases the current algorithm yielded better results in terms of total distance travelled and the average number of vehicles used.展开更多
This paper presents a method for optimal sizing of an off-grid hybrid microgrid (MG) system in order to achieve a certain load demand. The hybrid MG is made of a solar photovoltaic (PV) system, wind turbine (TW) and e...This paper presents a method for optimal sizing of an off-grid hybrid microgrid (MG) system in order to achieve a certain load demand. The hybrid MG is made of a solar photovoltaic (PV) system, wind turbine (TW) and energy storage system (ESS). The reliability of the MG system is modeled based on the loss of power supply probability (SPSP). For optimization, an enhanced Genetic Algorithm (GA) is used to minimize the total cost of the system over a 20-year period, while satisfying some reliability and operation constraints. A case study addressing optimal sizing of an off-grid hybrid microgrid in Nigeria is discussed. The result is compared with results obtained from the Brute Force and standard GA methods.展开更多
By virtue of alternating direction method of multipliers(ADMM), Newton-Raphson method, ratio consensus approach and running sum method, two distributed iterative strategies are presented in this paper to address the e...By virtue of alternating direction method of multipliers(ADMM), Newton-Raphson method, ratio consensus approach and running sum method, two distributed iterative strategies are presented in this paper to address the economic dispatch problem(EDP) in power systems. Different from most of the existing distributed ED approaches which neglect the effects of packet drops or/and time delays, this paper takes into account both packet drops and time delays which frequently occur in communication networks. Moreover, directed and possibly unbalanced graphs are considered in our algorithms, over which many distributed approaches fail to converge. Furthermore, the proposed schemes can address the EDP with local constraints of generators and nonquadratic convex cost functions, not just quadratic ones required in some existing ED approaches. Both theoretical analyses and simulation studies are provided to demonstrate the effectiveness of the proposed schemes.展开更多
The paper dwells on the unified power quality indexes characterizing the phenomenon of voltage unbalance in three-phase systems. Voltage unbalance is one of the commonest occurrences in the town mains of 0.38 kV volta...The paper dwells on the unified power quality indexes characterizing the phenomenon of voltage unbalance in three-phase systems. Voltage unbalance is one of the commonest occurrences in the town mains of 0.38 kV voltage. The phenomenon describes as inequality of vector magnitude of phase voltage and shearing angle between them. Causes and consequences of the voltage unbalance in distribution networks have been considered. The algorithm, which allows switching one-phase load, has been developed as one of the methods of reducing the unbalance level. The algorithm is written in the function block diagram programming language. For determining the duration and magnitude of the unbalance level it is proposed to introduce the forecasting algorithm. The necessary data for forecasting are accumulated in the course of the algorithm based on the Function Block Diagram. The algorithm example is given for transforming substation of the urban electrical power supply system. The results of the economic efficiency assessment of the algorithm implementation are shown in conclusion. The use of automatic switching of the one-phase load for explored substation allows reducing energy losses (active electric energy by 7.63%;reactive energy by 8.37%). It also allows improving supply quality to a consumer. For explored substation the average zero-sequence unbalance factor has dropped from 3.59% to 2.13%, and the negative-sequence unbalance factor has dropped from 0.61% to 0.36%.展开更多
Based on the research of predictingβ-hairpin motifs in proteins, we apply Random Forest and Support Vector Machine algorithm to predictβ-hairpin motifs in ArchDB40 dataset. The motifs with the loop length of 2 to 8 ...Based on the research of predictingβ-hairpin motifs in proteins, we apply Random Forest and Support Vector Machine algorithm to predictβ-hairpin motifs in ArchDB40 dataset. The motifs with the loop length of 2 to 8 amino acid residues are extracted as research object and thefixed-length pattern of 12 amino acids are selected. When using the same characteristic parameters and the same test method, Random Forest algorithm is more effective than Support Vector Machine. In addition, because of Random Forest algorithm doesn’t produce overfitting phenomenon while the dimension of characteristic parameters is higher, we use Random Forest based on higher dimension characteristic parameters to predictβ-hairpin motifs. The better prediction results are obtained;the overall accuracy and Matthew’s correlation coefficient of 5-fold cross-validation achieve 83.3% and 0.59, respectively.展开更多
Radio Cognitive (RC) is the new concept introduced to improve spectrum utilization in wireless communication and present important research field to resolve the spectrum scarcity problem. The powerful ability of CR to...Radio Cognitive (RC) is the new concept introduced to improve spectrum utilization in wireless communication and present important research field to resolve the spectrum scarcity problem. The powerful ability of CR to change and adapt its transmit parameters according to environmental sensed parameters, makes CR as the leading technology to manage spectrum allocation and respond to QoS provisioning. In this paper, we assume that the radio environment has been sensed and that the SU specifies QoS requirements of the wireless application. We use genetic algorithm (GA) and propose crossover method called Combined Single-Heuristic Crossover. The weighted sum multi-objective approach is used to combine performance objectives functions discussed in this paper and BER approximate formula is considered.展开更多
The common failure mechanism for brittle rocks is known to be axial splitting which happens parallel to the direction of maximum compression. One of the mechanisms proposed for modelling of axial splitting is the slid...The common failure mechanism for brittle rocks is known to be axial splitting which happens parallel to the direction of maximum compression. One of the mechanisms proposed for modelling of axial splitting is the sliding crack or so called, “wing crack” model. Fairhurst-Cook model explains this specific type of failure which starts by a pre-crack and finally breaks the rock by propagating 2-D cracks under uniaxial compression. In this paper, optimization of this model has been considered and the process has been done by a complete sensitivity analysis on the main parameters of the model and excluding the trends of their changes and also their limits and “peak points”. Later on this paper, three artificial intelligence algorithms including Particle Swarm Intelligence (PSO), Ant Colony Optimization (ACO) and genetic algorithm (GA) has been used and compared in order to achieve optimized sets of parameters resulting in near-maximum or near-minimum amounts of wedging forces creating a wing crack.展开更多
In this paper, we present a novel and efficient method for the design of a sharp, two dimensional (2D) wideband, circularly symmetric, FIR filter. First of all, a sharp one dimensional (1D) infinite precision FIR filt...In this paper, we present a novel and efficient method for the design of a sharp, two dimensional (2D) wideband, circularly symmetric, FIR filter. First of all, a sharp one dimensional (1D) infinite precision FIR filter is designed using the Frequency Response Masking (FRM) technique. This filter is converted into a multiplier-less filter by representing it in the Canonic Signed Digit (CSD) space. The design of the FRM filter in the CSD space calls for the use of a discrete optimization technique. To this end, a new optimization approach is proposed using a modified Harmony Search Algorithm (HSA). HSA is modified in such a way that, in every exploitation and exploration phase, the candidate solutions turns out to be integers. The 1D FRM multiplier-less filter, is in turn transformed to the 2D equivalent using the recently proposed multiplier-less transformations namely, T1 and T2. These transformations are successful in generating circular contours even for wideband filters. Since multipliers are the most power consuming elements in a 2D filter, the multiplier-less realization calls for reduced power consumption as well as computation time. Significant reduction in the computational complexity and computation time are the highlights of our proposed design technique. Besides, the proposed discrete optimization using modified HSA can be used to solve optimization problems in other engineering disciplines, where the search space consists of integers.展开更多
文摘This paper presents a binary gravitational search algorithm (BGSA) is applied to solve the problem of optimal allotment of DG sets and Shunt capacitors in radial distribution systems. The problem is formulated as a nonlinear constrained single-objective optimization problem where the total line loss (TLL) and the total voltage deviations (TVD) are to be minimized separately by incorporating optimal placement of DG units and shunt capacitors with constraints which include limits on voltage, sizes of installed capacitors and DG. This BGSA is applied on the balanced IEEE 10 Bus distribution network and the results are compared with conventional binary particle swarm optimization.
文摘Two new regularization algorithms for solving the first-kind Volterra integral equation, which describes the pressure-rate deconvolution problem in well test data interpretation, are developed in this paper. The main features of the problem are the strong nonuniform scale of the solution and large errors (up to 15%) in the input data. In both algorithms, the solution is represented as decomposition on special basic functions, which satisfy given a priori information on solution, and this idea allow us significantly to improve the quality of approximate solution and simplify solving the minimization problem. The theoretical details of the algorithms, as well as the results of numerical experiments for proving robustness of the algorithms, are presented.
文摘Numerous cryptographic algorithms (ElGamal, Rabin, RSA, NTRU etc) require multiple computations of modulo multiplicative inverses. This paper describes and validates a new algorithm, called the Enhanced Euclid Algorithm, for modular multiplicative inverse (MMI). Analysis of the proposed algorithm shows that it is more efficient than the Extended Euclid algorithm (XEA). In addition, if a MMI does not exist, then it is not necessary to use the Backtracking procedure in the proposed algorithm;this case requires fewer operations on every step (divisions, multiplications, additions, assignments and push operations on stack), than the XEA. Overall, XEA uses more multiplications, additions, assignments and twice as many variables than the proposed algorithm.
基金the National Natural Science Foundation of China(No.51575328,61503232).
文摘The contradiction of variable step size least mean square(LMS)algorithm between fast convergence speed and small steady-state error has always existed.So,a new algorithm based on the combination of logarithmic and symbolic function and step size factor is proposed.It establishes a new updating method of step factor that is related to step factor and error signal.This work makes an analysis from 3 aspects:theoretical analysis,theoretical verification and specific experiments.The experimental results show that the proposed algorithm is superior to other variable step size algorithms in convergence speed and steady-state error.
文摘This work proposes a novel approach for multi-type optimal placement of flexible AC transmission system(FACTS) devices so as to optimize multi-objective voltage stability problem. The current study discusses a way for locating and setting of thyristor controlled series capacitor(TCSC) and static var compensator(SVC) using the multi-objective optimization approach named strength pareto multi-objective evolutionary algorithm(SPMOEA). Maximization of the static voltage stability margin(SVSM) and minimizations of real power losses(RPL) and load voltage deviation(LVD) are taken as the goals or three objective functions, when optimally locating multi-type FACTS devices. The performance and effectiveness of the proposed approach has been validated by the simulation results of the IEEE 30-bus and IEEE 118-bus test systems. The proposed approach is compared with non-dominated sorting particle swarm optimization(NSPSO) algorithm. This comparison confirms the usefulness of the multi-objective proposed technique that makes it promising for determination of combinatorial problems of FACTS devices location and setting in large scale power systems.
文摘In this paper we consider a parallel algorithm that detects the maximizer of unimodal function f(x) computable at every point on unbounded interval (0, ∞). The algorithm consists of two modes: scanning and detecting. Search diagrams are introduced as a way to describe parallel searching algorithms on unbounded intervals. Dynamic programming equations, combined with a series of liner programming problems, describe relations between results for every pair of successive evaluations of function f in parallel. Properties of optimal search strategies are derived from these equations. The worst-case complexity analysis shows that, if the maximizer is located on a priori unknown interval (n-1], then it can be detected after cp(n)=「2log「p/2」+1(n+1)」-1 parallel evaluations of f(x), where p is the number of processors.
文摘AIM To examine the practice pattern in Kaiser Permanente Southern California(KPSC), i.e., gastroenterology(GI)/surgery referrals and endoscopic ultrasound(EUS), for pancreatic cystic neoplasms(PCNs) after the regionwide dissemination of the PCN management algorithm.METHODS Retrospective review was performed; patients with PCN diagnosis given between April 2012 and April 2015(18 mo before and after the publication of the algorithm) in KPSC(integrated health system with 15 hospitals and 202 medical offices in Southern California) were identified.RESULTS2558(1157 pre-and 1401 post-algorithm) received a new diagnosis of PCN in the study period. There was no difference in the mean cyst size(pre-19.1 mm vs post-18.5 mm, P = 0.119). A smaller percentage of PCNs resulted in EUS after the implementation of the algorithm(pre-45.5% vs post-34.8%, P < 0.001). A smaller proportion of patients were referred for GI(pre-65.2% vs post-53.3%, P < 0.001) and surgery consultations(pre-24.8% vs post-16%, P < 0.001) for PCN after the implementation. There was no significant change in operations for PCNs. Cost of diagnostic care was reduced after the implementation by 24%, 18%, and 36% for EUS, GI, and surgery consultations, respectively, with total cost saving of 24%.CONCLUSION In the current healthcare climate, there is increased need to optimize resource utilization. Dissemination of an algorithm for PCN management in an integrated health system resulted in fewer EUS and GI/surgery referrals, likely by aiding the physicians ordering imaging studies in the decision making for the management of PCNs. This translated to cost saving of 24%, 18%, and 36% for EUS, GI, and surgical consultations, respectively, with total diagnostic cost saving of 24%.
文摘In biology, signal transduction refers to a process by which a cell converts one kind of signal or stimulus into another. It involves ordered sequences of biochemical reactions inside the cell. These cascades of reactions are carried out by enzymes and activated by second messengers. Signal transduction pathways are complex in nature. Each pathway is responsible for tuning one or more biological functions in the intracellular environment as well as more than one pathway interact among themselves to carry forward a single biological function. Such kind of behavior of these pathways makes understanding difficult. Hence, for the sake of simplicity, they need to be partitioned into smaller modules and then analyzed. We took VEGF signaling pathway, which is responsible for angiogenesis for this kind of modularized study. Modules were obtained by applying the algorithm of Nayak and De (Nayak and De, 2007) for different complexity values. These sets of modules were compared among themselves to get the best set of modules for an optimal complexity value. The best set of modules compared with four different partitioning algorithms namely, Farhat’s (Farhat, 1998), Greedy (Chartrand and Oellermann, 1993), Kernighan-Lin’s (Kernighan and Lin, 1970) and Newman’s community finding algorithm (Newman, 2006). These comparisons enabled us to decide which of the aforementioned algorithms was the best one to create partitions from human VEGF signaling pathway. The optimal complexity value, on which the best set of modules was obtained, was used to get modules from different species for comparative study. Comparison among these modules would shed light on the trend of development of VEGF signaling pathway over these species.
基金the Deputyship for Research and Innovation,“Ministry of Education”in Saudi Arabia for funding this research(IFKSUOR3-014-3).
文摘In this study,our aim is to address the problem of gene selection by proposing a hybrid bio-inspired evolutionary algorithm that combines Grey Wolf Optimization(GWO)with Harris Hawks Optimization(HHO)for feature selection.Themotivation for utilizingGWOandHHOstems fromtheir bio-inspired nature and their demonstrated success in optimization problems.We aimto leverage the strengths of these algorithms to enhance the effectiveness of feature selection in microarray-based cancer classification.We selected leave-one-out cross-validation(LOOCV)to evaluate the performance of both two widely used classifiers,k-nearest neighbors(KNN)and support vector machine(SVM),on high-dimensional cancer microarray data.The proposed method is extensively tested on six publicly available cancer microarray datasets,and a comprehensive comparison with recently published methods is conducted.Our hybrid algorithm demonstrates its effectiveness in improving classification performance,Surpassing alternative approaches in terms of precision.The outcomes confirm the capability of our method to substantially improve both the precision and efficiency of cancer classification,thereby advancing the development ofmore efficient treatment strategies.The proposed hybridmethod offers a promising solution to the gene selection problem in microarray-based cancer classification.It improves the accuracy and efficiency of cancer diagnosis and treatment,and its superior performance compared to other methods highlights its potential applicability in realworld cancer classification tasks.By harnessing the complementary search mechanisms of GWO and HHO,we leverage their bio-inspired behavior to identify informative genes relevant to cancer diagnosis and treatment.
文摘In this paper, a new class of over-relaxed proximal point algorithms for solving nonlinear operator equations with (A,η,m)-monotonicity framework in Hilbert spaces is introduced and studied. Further, by using the generalized resolvent operator technique associated with the (A,η,m)-monotone operators, the approximation solvability of the operator equation problems and the convergence of iterative sequences generated by the algorithm are discussed. Our results improve and generalize the corresponding results in the literature.
文摘In this paper, the application of modified genetic algorithms (MGA) in the optimization of the ARX Model-based observer of the Pneumatic Artificial Muscle (PAM) manipulator is investigated. The new MGA algorithm is proposed from the genetic algorithm with important additional strategies, and consequently yields a faster convergence and a more accurate search. Firstly, MGA-based identification method is used to identify the parameters of the nonlinear PAM manipulator described by an ARX model in the presence of white noise and this result will be validated by MGA and compared with the simple genetic algorithm (GA) and LMS (Least mean-squares) method. Secondly, the intrinsic features of the hysteresis as well as other nonlinear disturbances existing intuitively in the PAM system are estimated online by a Modified Recursive Least Square (MRLS) method in identification experiment. Finally, a highly efficient self-tuning control algorithm Minimum Variance Control (MVC) is taken for tracking the joint angle position trajectory of this PAM manipulator. Experiment results are included to demonstrate the excellent performance of the MGA algorithm in the NARX model-based MVC control system of the PAM system. These results can be applied to model, identify and control other highly nonlinear systems as well.
文摘In certain computational systems the amount of space required to execute an algorithm is even more restrictive than the corresponding time necessary for solution of a problem. In this paper an algorithm for modular multiplicative inverse is introduced and its computational space complexity is analyzed. A tight upper bound for bit storage required for execution of the algorithm is provided. It is demonstrated that for range of numbers used in public-key encryption systems, the size of bit storage does not exceed a 2K-bit threshold in the worst-case. This feature of the Enhanced-Euclid algorithm allows designing special-purpose hardware for its implementation as a subroutine in communication-secure wireless devices.
文摘The VRP is classified as an NP-hard problem. Hence exact optimization methods may be difficult to solve these problems in acceptable CPU times, when the problem involves real-world data sets that are very large. To get solutions in determining routes which are realistic and very close to the actual solution, we use heuristics and metaheuristics which are of the combinatorial optimization type. A literature review of VRPTW, TDVRP, and a metaheuristic such as the genetic algorithm was conducted. In this paper, the implementation of the VRPTW and its extension, the time-dependent VRPTW (TDVRPTW) has been carried out using the model as well as metaheuristics such as the genetic algorithm (GA). The algorithms were implemented, using Matlab and HeuristicLab optimization software. A plugin was developed using Visual C# and DOT NET framework 4.5. Results were tested using Solomon’s 56 benchmark instances classified into groups such as C1, C2, R1, R2, RC1, RC2, with 100 customer nodes, 25 vehicles and each vehicle capacity of 200. The results were comparable to the earlier algorithms developed and in some cases the current algorithm yielded better results in terms of total distance travelled and the average number of vehicles used.
文摘This paper presents a method for optimal sizing of an off-grid hybrid microgrid (MG) system in order to achieve a certain load demand. The hybrid MG is made of a solar photovoltaic (PV) system, wind turbine (TW) and energy storage system (ESS). The reliability of the MG system is modeled based on the loss of power supply probability (SPSP). For optimization, an enhanced Genetic Algorithm (GA) is used to minimize the total cost of the system over a 20-year period, while satisfying some reliability and operation constraints. A case study addressing optimal sizing of an off-grid hybrid microgrid in Nigeria is discussed. The result is compared with results obtained from the Brute Force and standard GA methods.
基金supported by the National Natural Science Foundation of China(61673077)。
文摘By virtue of alternating direction method of multipliers(ADMM), Newton-Raphson method, ratio consensus approach and running sum method, two distributed iterative strategies are presented in this paper to address the economic dispatch problem(EDP) in power systems. Different from most of the existing distributed ED approaches which neglect the effects of packet drops or/and time delays, this paper takes into account both packet drops and time delays which frequently occur in communication networks. Moreover, directed and possibly unbalanced graphs are considered in our algorithms, over which many distributed approaches fail to converge. Furthermore, the proposed schemes can address the EDP with local constraints of generators and nonquadratic convex cost functions, not just quadratic ones required in some existing ED approaches. Both theoretical analyses and simulation studies are provided to demonstrate the effectiveness of the proposed schemes.
文摘The paper dwells on the unified power quality indexes characterizing the phenomenon of voltage unbalance in three-phase systems. Voltage unbalance is one of the commonest occurrences in the town mains of 0.38 kV voltage. The phenomenon describes as inequality of vector magnitude of phase voltage and shearing angle between them. Causes and consequences of the voltage unbalance in distribution networks have been considered. The algorithm, which allows switching one-phase load, has been developed as one of the methods of reducing the unbalance level. The algorithm is written in the function block diagram programming language. For determining the duration and magnitude of the unbalance level it is proposed to introduce the forecasting algorithm. The necessary data for forecasting are accumulated in the course of the algorithm based on the Function Block Diagram. The algorithm example is given for transforming substation of the urban electrical power supply system. The results of the economic efficiency assessment of the algorithm implementation are shown in conclusion. The use of automatic switching of the one-phase load for explored substation allows reducing energy losses (active electric energy by 7.63%;reactive energy by 8.37%). It also allows improving supply quality to a consumer. For explored substation the average zero-sequence unbalance factor has dropped from 3.59% to 2.13%, and the negative-sequence unbalance factor has dropped from 0.61% to 0.36%.
文摘Based on the research of predictingβ-hairpin motifs in proteins, we apply Random Forest and Support Vector Machine algorithm to predictβ-hairpin motifs in ArchDB40 dataset. The motifs with the loop length of 2 to 8 amino acid residues are extracted as research object and thefixed-length pattern of 12 amino acids are selected. When using the same characteristic parameters and the same test method, Random Forest algorithm is more effective than Support Vector Machine. In addition, because of Random Forest algorithm doesn’t produce overfitting phenomenon while the dimension of characteristic parameters is higher, we use Random Forest based on higher dimension characteristic parameters to predictβ-hairpin motifs. The better prediction results are obtained;the overall accuracy and Matthew’s correlation coefficient of 5-fold cross-validation achieve 83.3% and 0.59, respectively.
文摘Radio Cognitive (RC) is the new concept introduced to improve spectrum utilization in wireless communication and present important research field to resolve the spectrum scarcity problem. The powerful ability of CR to change and adapt its transmit parameters according to environmental sensed parameters, makes CR as the leading technology to manage spectrum allocation and respond to QoS provisioning. In this paper, we assume that the radio environment has been sensed and that the SU specifies QoS requirements of the wireless application. We use genetic algorithm (GA) and propose crossover method called Combined Single-Heuristic Crossover. The weighted sum multi-objective approach is used to combine performance objectives functions discussed in this paper and BER approximate formula is considered.
文摘The common failure mechanism for brittle rocks is known to be axial splitting which happens parallel to the direction of maximum compression. One of the mechanisms proposed for modelling of axial splitting is the sliding crack or so called, “wing crack” model. Fairhurst-Cook model explains this specific type of failure which starts by a pre-crack and finally breaks the rock by propagating 2-D cracks under uniaxial compression. In this paper, optimization of this model has been considered and the process has been done by a complete sensitivity analysis on the main parameters of the model and excluding the trends of their changes and also their limits and “peak points”. Later on this paper, three artificial intelligence algorithms including Particle Swarm Intelligence (PSO), Ant Colony Optimization (ACO) and genetic algorithm (GA) has been used and compared in order to achieve optimized sets of parameters resulting in near-maximum or near-minimum amounts of wedging forces creating a wing crack.
文摘In this paper, we present a novel and efficient method for the design of a sharp, two dimensional (2D) wideband, circularly symmetric, FIR filter. First of all, a sharp one dimensional (1D) infinite precision FIR filter is designed using the Frequency Response Masking (FRM) technique. This filter is converted into a multiplier-less filter by representing it in the Canonic Signed Digit (CSD) space. The design of the FRM filter in the CSD space calls for the use of a discrete optimization technique. To this end, a new optimization approach is proposed using a modified Harmony Search Algorithm (HSA). HSA is modified in such a way that, in every exploitation and exploration phase, the candidate solutions turns out to be integers. The 1D FRM multiplier-less filter, is in turn transformed to the 2D equivalent using the recently proposed multiplier-less transformations namely, T1 and T2. These transformations are successful in generating circular contours even for wideband filters. Since multipliers are the most power consuming elements in a 2D filter, the multiplier-less realization calls for reduced power consumption as well as computation time. Significant reduction in the computational complexity and computation time are the highlights of our proposed design technique. Besides, the proposed discrete optimization using modified HSA can be used to solve optimization problems in other engineering disciplines, where the search space consists of integers.