In this in-depth exploration, I delve into the complex implications and costs of cybersecurity breaches. Venturing beyond just the immediate repercussions, the research unearths both the overt and concealed long-term ...In this in-depth exploration, I delve into the complex implications and costs of cybersecurity breaches. Venturing beyond just the immediate repercussions, the research unearths both the overt and concealed long-term consequences that businesses encounter. This study integrates findings from various research, including quantitative reports, drawing upon real-world incidents faced by both small and large enterprises. This investigation emphasizes the profound intangible costs, such as trade name devaluation and potential damage to brand reputation, which can persist long after the breach. By collating insights from industry experts and a myriad of research, the study provides a comprehensive perspective on the profound, multi-dimensional impacts of cybersecurity incidents. The overarching aim is to underscore the often-underestimated scope and depth of these breaches, emphasizing the entire timeline post-incident and the urgent need for fortified preventative and reactive measures in the digital domain.展开更多
The presented paper is dedicated to a new ret-rospective view on the history of natural sci-ences in XX-XXI cc, partially including the sci-ence philosophy (mainly, the problems of the scientific realism, i.e. the cor...The presented paper is dedicated to a new ret-rospective view on the history of natural sci-ences in XX-XXI cc, partially including the sci-ence philosophy (mainly, the problems of the scientific realism, i.e. the correspondence of science to reality) and also a novel scheme for different classes of sciences with different ob-jects and paradigms. There are analyzed the chosen “great” and “grand” problems of phys-ics (including the comprehension of quantum mechanics, with a recently elaborated new chapter, connected with time as a quantum obs- ervable and time analysis of quantum processes) and also of natural sciences as a whole. The particular attention is paid to the interpretation questions and slightly to the aspects, inevitably connected with the world- views of the res- earchers (which do often constitute a part of the interpretation questions).展开更多
Polymer flooding has been proven to effectively improve oil recovery in the Bohai Oil Field. However, due to high oil viscosity and significant formation heterogeneity, it is necessary to further improve the displacem...Polymer flooding has been proven to effectively improve oil recovery in the Bohai Oil Field. However, due to high oil viscosity and significant formation heterogeneity, it is necessary to further improve the displacement effectiveness of polymer flooding in heavy oil reservoirs in the service life of offshore platforms. In this paper, the effects of the water/oil mobility ratio in heavy oil reservoirs and the dimensionless oil productivity index on polymer flooding effectiveness were studied utilizing rel- ative permeability curves. The results showed that when the water saturation was less than the value, where the water/oil mobility ratio was equal to 1, polymer flooding could effectively control the increase of fractional water flow, which meant that the upper limit of water/oil ratio suitable for polymer flooding should be the value when the water/oil mobility ratio was equal to 1. Mean while, by injecting a certain volume of water to create water channels in the reservoir, the polymer flooding would be the most effective in improving sweep efficiency, and lower the fractional flow of water to the value corresponding to △Jmax. Considering the service life of the platform and the polymer mobility control capacity, the best polymer injection timing for heavy oil reservoirs was optimized. It has been tested for reservoirs with crude oil viscosity of 123 and 70 mPa s, the optimum polymer flooding effec- tiveness could be obtained when the polymer floods were initiated at the time when the fractional flow of water were 10 % and 25 %, respectively. The injection timing range for polymer flooding was also theoretically analyzed for the Bohai Oil Field utilizing which provided methods for effectiveness. relative permeability curves, improving polymer flooding展开更多
This paper formulates the light timing calculations for each interferometer arm;one that is parallel to the direction of motion of the interferometer through space and the other that is perpendicular. The calculations...This paper formulates the light timing calculations for each interferometer arm;one that is parallel to the direction of motion of the interferometer through space and the other that is perpendicular. The calculations are done for a vacuum-mode interferometer and then for a gas-mode interferometer. The calculations show that no light timing difference is detectable in a vacuum-mode interferometer, but once an optical medium is present in the light path down the arms of the interferometer, this is no longer the case and a timing difference is detectable. Further to this, the timing equations obtained from the analysis are used to model the historical experiments of Michelson-Morley and Miller (Mt Wilson) and predictions are made by the model that accurately match the actual recorded results from those experiments. Thus, this timing analysis confirms that there is a light speed anisotropy in a reference frame that is moving through space, indicating the presence of a preferred Aether reference frame through which the Earth is moving.展开更多
This paper examines how cybersecurity is developing and how it relates to more conventional information security. Although information security and cyber security are sometimes used synonymously, this study contends t...This paper examines how cybersecurity is developing and how it relates to more conventional information security. Although information security and cyber security are sometimes used synonymously, this study contends that they are not the same. The concept of cyber security is explored, which goes beyond protecting information resources to include a wider variety of assets, including people [1]. Protecting information assets is the main goal of traditional information security, with consideration to the human element and how people fit into the security process. On the other hand, cyber security adds a new level of complexity, as people might unintentionally contribute to or become targets of cyberattacks. This aspect presents moral questions since it is becoming more widely accepted that society has a duty to protect weaker members of society, including children [1]. The study emphasizes how important cyber security is on a larger scale, with many countries creating plans and laws to counteract cyberattacks. Nevertheless, a lot of these sources frequently neglect to define the differences or the relationship between information security and cyber security [1]. The paper focus on differentiating between cybersecurity and information security on a larger scale. The study also highlights other areas of cybersecurity which includes defending people, social norms, and vital infrastructure from threats that arise from online in addition to information and technology protection. It contends that ethical issues and the human factor are becoming more and more important in protecting assets in the digital age, and that cyber security is a paradigm shift in this regard [1].展开更多
This is a Unified Field description based on the holographic Time Dilation Cosmology, TDC, model, which is an eternal continuum evolving forward in the forward direction of time, at the speed of light, c, at an invari...This is a Unified Field description based on the holographic Time Dilation Cosmology, TDC, model, which is an eternal continuum evolving forward in the forward direction of time, at the speed of light, c, at an invariant 1 s/s rate of time. This is the Fundamental Direction of Evolution, FDE. There is also an evolution down time dilation gradients, the Gravitational Direction of Evolution, GDE. These evolutions are gravity, which is the evolutionary force in time. Gravitational velocities are compensation for the difference in the rate of time, dRt, in a dilation field, and the dRtis equal to the compensatory velocity’s percentage of c, and is a measure of the force in time inducing the velocity. In applied force induced velocities, the dRt is a measure of the resistance in time to the induced velocity, which might be called “anti-gravity” or “negative gravity”. The two effects keep the continuum uniformly evolving forward at c. It is demonstrated that gravity is already a part of the electromagnetic field equations in way of the dRt element contained in the TDC velocity formula. Einstein’s energy formula is defined as a velocity formula and a modified version is used for charged elementary particle solutions. A time dilation-based derivation of the Lorentz force ties gravity directly to the electromagnetic field proving the unified field of gravity and the EMF. It is noted how we could possibly create gravity drives. This is followed by a discussion of black holes, proving supermassive objects, like massive black hole singularities, are impossible, and that black holes are massless Magnetospheric Eternally Collapsing Objects (MECOs) that are vortices in spacetime. .展开更多
Apart from listening to the cry of a healthy newborn,it is the declaration by the attending paediatrician in the labour room that the child is normal which brings utmost joy to parents.The global incidence of children...Apart from listening to the cry of a healthy newborn,it is the declaration by the attending paediatrician in the labour room that the child is normal which brings utmost joy to parents.The global incidence of children born with congenital anomalies has been reported to be 3%-6%with more than 90%of these occurring in low-and middle-income group countries.The exact percentages/total numbers of children requiring surgical treatment cannot be estimated for several reasons.These children are operated under several surgical disciplines,viz,paediatric-,plastic reconstructive,neuro-,cardiothoracic-,orthopaedic surgery etc.These conditions may be life-threatening,e.g.,trachea-oesophageal fistula,critical pulmonary stenosis,etc.and require immediate surgical intervention.Some,e.g.,hydrocephalus,may need intervention as soon as the patient is fit for surgery.Some,e.g.,patent ductus arteriosus need‘wait and watch’policy up to a certain age in the hope of spontaneous recovery.Another extremely important category is that of patients where the operative intervention is done based on their age.Almost all the congenital anomalies coming under care of a plastic surgeon are operated as elective surgery(many as multiple stages of correction)at appropriate ages.There are advantages and disadvantages of intervention at different ages.In this article,we present a review of optimal timings,along with reasoning,for surgery of many of the common congenital anomalies which are treated by plastic surgeons.Obstetricians,paediatricians and general practitioners/family physicians,who most often are the first ones to come across such children,must know to guide the parents appropriately and convincingly impress upon the them as to why their child should not be operated immediately and also the consequences of too soon or too late.展开更多
Shuxuetong injection composed of leech(Hirudo nipponica Whitman) and earthworm(Pheretima aspergillum) has been used for the clinical treatment of acute stroke for many years in China. However, the precise neuroprotect...Shuxuetong injection composed of leech(Hirudo nipponica Whitman) and earthworm(Pheretima aspergillum) has been used for the clinical treatment of acute stroke for many years in China. However, the precise neuroprotective mechanism of Shuxuetong injection remains poorly understood. Here, cerebral microvascular endothelial cells(bEnd.3) were incubated in glucose-free Dulbecco's modified Eagle's medium containing 95% N_2/5% CO_2 for 6 hours, followed by high-glucose medium containing 95% O_2 and 5% CO_2 for 18 hours to establish an oxygen-glucose deprivation/reperfusion model. This in vitro cell model was administered Shuxuetong injection at 1/32, 1/64, and 1/128 concentrations(diluted 32-, 64-, and 128-times). Cell Counting Kit-8 assay was used to evaluate cell viability. A fluorescence method was used to measure lactate dehydrogenase, and a fluorescence microplate reader used to detect intracellular reactive oxygen species. A fluorescent probe was also used to measure mitochondrial superoxide production. A cell resistance meter was used to measure transepithelial resistance and examine integrity of monolayer cells. The fluorescein isothiocyanate-dextran test was performed to examine blood-brain barrier permeability. Real-time reverse transcription polymerase chain reaction was performed to analyze mRNA expression levels of tumor necrosis factor alpha, interleukin-1β, interleukin-6, and inducible nitric oxide synthase. Western blot assay was performed to analyze expression of caspase-3, intercellular adhesion molecule 1, vascular cell adhesion molecule 1, occludin, vascular endothelial growth factor, cleaved caspase-3, B-cell lymphoma 2, phosphorylated extracellular signal-regulated protein kinase, extracellular signal-regulated protein kinase, nuclear factor-κB p65, I kappa B alpha, phosphorylated I kappa B alpha, I kappa B kinase, phosphorylated I kappa B kinase, claudin-5, and zonula occludens-1. Our results show that Shuxuetong injection increases bEnd.3 cell viability and B-cell lymphoma 2 expression, reduces cleaved caspase-3 expression, inhibits production of reactive oxygen species and mitochondrial superoxide, suppresses expression of tumor necrosis factor alpha, interleukin-1β, interleukin-6, inducible nitric oxide synthase mRNA, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1, markedly increases transepithelial resistance, decreases blood-brain barrier permeability, upregulates claudin-5, occludin, and zonula occludens-1 expression, reduces nuclear factor-κB p65 and vascular endothelial growth factor expression, and reduces I kappa B alpha, extracellular signal-regulated protein kinase 1/2, and I kappa B kinase phosphorylation levels. Overall, these findings suggest that Shuxuetong injection has protective effects on brain microvascular endothelial cells after oxygen-glucose deprivation/reperfusion. Moreover, its protective effect is associated with reduction of mitochondrial superoxide production, inhibition of the inflammatory response, and inhibition of vascular endothelial growth factor, extracellular signal-regulated protein kinase 1/2, and the nuclear factor-κB p65 signaling pathway.展开更多
The beneficial acclimation hypothesis (BAH) predicts that animals acclimated to a particular temperature have enhanced performance or fitness at that temperature in comparison with animals acclimated to other temperat...The beneficial acclimation hypothesis (BAH) predicts that animals acclimated to a particular temperature have enhanced performance or fitness at that temperature in comparison with animals acclimated to other temperatures. The BAH has been tested by a variety of empirical examinations, and was rejected by some of them. In order to provide new evidences for the BAH, the effects of acute and acclimation temperature (AT) on locomotor performance of Macrobiotus hufelandi (Tardigrada: Macrobiotidae) were investigated. The tardigrades were collected from Nanwutai, Qinling Mountains which traverse from west to east in central China. The subjects were acclimated to either 2℃ or 22℃ for 2 weeks. The animal was transferred onto a frosted slide and allowed to walk freely at the performance temperature (PT) 2℃ or 22℃. Only one individual was tested per test bout, which lasted from three to five minutes. To avoid occurrence of thermal acclimation effect, the standard adaptation time was limited to 1.5 min. Each subject was tested for once at the same PT, and was tested only at one PT. A total of 25 individuals were tested and measured at the same PT. The locomotor performance of the animals was recorded with a digital video camera mounted on a microscope at 4×10 amplification and replayed on a PC. Every subject was identified. Walking speed (WS) and percentage of time moving (PTM) at both PTs (2℃ or 22℃) were selected as the rate parameters of locomotor performance. The two-way repeated measures ANOVA with a significance level of α= 0.05 and Duncan multiple range test were used to analyze the data. WS of the animals acclimated to and tested at the same temperatures was significantly faster than that for animals acclimated to and tested at the different temperatures, similarly, PTM of the animals acclimated to 22℃ and tested at 22℃ was significantly greater than PTM of animals acclimated to 22℃ and tested at 2℃, which indicated that the animals acclimated to a particular temperature have enhanced locomotor performance in that temperature relative to the animals acclimated to that temperature in other thermal environment. WS of the animals acclimated to 22℃ and tested at 22℃ was significantly faster than WS of animals acclimated to 2℃ and tested at 22℃, PTM of the animals acclimated to 22℃ and tested at 22℃ was significantly greater than PTM of animals acclimated to 2℃ and tested at 22℃. These results supported the BAH. It could be concluded that the PT and thermal acclimation as well as the interaction between the PT and AT significantly influence the locomotor performance of M.hufelandi, and that, despite the existence of a few results of this study that don’t support the BAH, some results of this study support for this hypothesis, and that the animals acclimated to a particular temperature have enhanced locomotor performance in that temperature relative to the animals acclimated to that temperature in other thermal environment, implying that any performance temperature that deviates from the acclimation temperature could cause the reduction of the walking speed which is closely related to the fitness of the M.hufelandi.展开更多
The reform of the housing system in Shanghai has unexpectedly given rise to a self-governed property owners’ collective supervisory system, primarily in the form of Property Owners’ Supervisory Council (POSC), which...The reform of the housing system in Shanghai has unexpectedly given rise to a self-governed property owners’ collective supervisory system, primarily in the form of Property Owners’ Supervisory Council (POSC), which has picked up some of the government’s administrative functions. Although this new, institutionalized management model has theoretically made democratic managerial participation at the grassroots level possible, it has brought about endless problems, overt and covert, shortly after its appearance, some of which are even alarming. A comprehensive analysis of the data collected over a long period of time has led to the conclusion that this system is a failure, attributable to the overt factor related to skills in reality and the covert “priori” factor that is masked by the former. The existence of such “priori” factor once again demonstrates the deep-rooted, traditional managerial logic: Positive operations is society need only to depend upon individuals’ unstable self-disciplined morality rather than to build a system. The current paper points out that any change in the socioeconomic structure that has long been subject to the power of politics is to inevitably incur a corresponding global structural accommodation, including politics itself. To respond to the two factors for the failure, system building in the two overlapping areas is a must.展开更多
Optimal detection of liquid ionization calorimeter signal in experimental particle physics is considered. A few linear and nonlinear approaches for amplitude and arrival time estimation based on the χ2 function are c...Optimal detection of liquid ionization calorimeter signal in experimental particle physics is considered. A few linear and nonlinear approaches for amplitude and arrival time estimation based on the χ2 function are compared in simulation considering the noise sample correlation introduced by the analog pulse shaper. The estimation bias of the first-order approximation, a.k.a linear optimal filtering, is studied and contrasted to those of the second-order as well as the exhaustive search. A gradient-descent technique is presented as an alternative to the exhaustive search with significantly reduced search time and computation complexity. Results from various pulse shapers including the CR-RC2, CR-RC3, and CR2-RC2 are also compared.展开更多
The article hypothesizes that DE and DM (UCM) are a “Form of Motion of a Special Nature”, where “Form of Motion” means “Eternal Motion” as the power of dynamics of different levels and varying degrees of self-su...The article hypothesizes that DE and DM (UCM) are a “Form of Motion of a Special Nature”, where “Form of Motion” means “Eternal Motion” as the power of dynamics of different levels and varying degrees of self-sufficiency, and by “Special Nature”, gravitational and two other properties of matter, “tied” to the “Eternal Movement” and completely dependent on it. Carriers of key properties of a “Special Nature” have been established: “0”-DE particles and “3”-DM particles (UDM). The unity of their inherent “motionally-gravitational” properties and the peculiarity of the relationship between “motion” and “gravity” are revealed: the higher the intensity of “Eternal Motion”, the stronger the gravitational properties of matter are manifested (and vice versa). The relationship of “time” with the “vibration frequency” and the “mass” of photons with the “degree of bonding and deformation properties of the field” is shown. The maximum level of gravity has been determined, which allows Nature to successfully create the Universe: such a landmark is the proximity to the property of the Primary Source—the “pure graviton” of the OSP space, the most powerful “motionally-gravitational” particle of the Universe. The reasons for the emergence of such an identity of the gravitational properties of particles with the indicators of a “pure graviton” are established: for “0”-DE particles, this is the acquisition of the function of “freedom of movement”;for “3”-DM particles (UDM), the creation of a special structure—a “double field” (“Main” and “Small”). The presence in the “double field” of specific “tools” for the creation of the worlds of the Universe—gravitational “waves” gives rise to impulses (shocks) of varying intensity and shape. A list of functions performed by “waves” in the “Main” and “Small” fields has been compiled. The specific conditions for the formation of “UDM Streams”, their transformation into a “Vortex” and, under the influence of a powerful Initial Impulse (push), sending them to the “place” of the creation of galaxies, are shown. It is suggested that there is a “Cycle of Matter in Nature” in the closed structure of our Universe due to the “work” of “waves” and the functioning of special “factories” in the form of exotic space objects—Black holes.展开更多
The Magneto-acoustic Tomography with Current Injection (MAT-CI) is a new biological electrical impedance imaging technique that combines Electrical Impedance Tomography (EIT) with Ultrasonic Imaging (UI), which posses...The Magneto-acoustic Tomography with Current Injection (MAT-CI) is a new biological electrical impedance imaging technique that combines Electrical Impedance Tomography (EIT) with Ultrasonic Imaging (UI), which possesses the non-invasive and high-contrast of the EIT and the high-resolution of the UI. The MAT-CI is expected to acquire high quality image and embraces a wide application. Its principle is to put the conductive sample in the Static Magnetic Field(SMF) and inject a time-varying current, during which the SMF and the current interact and generate the Lorentz Force that inspire ultrasonic signal received by the ultrasonic transducers positioned around the sample. And then according to related reconstruction algorithm and ultrasonic signal, electrical conductivity image is obtained. In this paper, a forward problem mathematical model of the MAT-CI has been set up to deduce the theoretical equation of the electromagnetic field and solve the sound source distribution by Green’s function. Secondly, a sound field restoration by Wiener filtering and reconstruction of current density by time-rotating method have deduced the Laplace’s equation that caters to the current density to further acquire the electrical conductivity distribution image of the sample through iteration method. In the end, double-loop coils experiments have been conducted to verify its feasibility.展开更多
In order to improve the performance of the rotary engine,this paper has designed a new type of dual-pit rotary engine combustion chamber structure,and compares the combustion and emission characteristics with the rota...In order to improve the performance of the rotary engine,this paper has designed a new type of dual-pit rotary engine combustion chamber structure,and compares the combustion and emission characteristics with the rotary engine with a traditional combustion chamber.The existence of the dual-pit combustion chamber strengthens the overall vortex intensity in the cylinder,effectively promotes the mixing process of fuel and air in the cylinder,the maximum combustion pressure in the cylinder increased by 8.6%,significantly increases the diffusion combustion speed,and significantly improves the dynamic performance of the rotary engine.On this basis,the effects of fuel injection timing parameters on fuel distribution,combustion and emission characteristics were studied.Fuel distribution is more even and dispersed during injection in the later stage of compression.When the fuel injection timing was 105°BTDC in the middle of the compression phase,the matching effect of fuel distribution law and ignition scheme was the best.When the injection timing was 75°BTDC and 85°BTDC in the late compression stage,the mass fraction of NOx remained at a low level.The correlation between soot generation and the change of fuel injection timing was weak.When the injection time was 85°BTDC,the soot generation remained at a relatively high level.展开更多
The emergence of the middle class was closely related to the appearance of industrial society and its consequential constant changes in the social structure. Karl Marx and other theorists in the same camp were among t...The emergence of the middle class was closely related to the appearance of industrial society and its consequential constant changes in the social structure. Karl Marx and other theorists in the same camp were among the earliest scholars who discussed that topic. For a quite long period of time, the debate was mainly focused on the characteristics of the “new middle class.” The middle class, however, has undergone a categorical transformation from the old to the new middle-class, and furthermore, this transformation itself has signified the transition in social patterns from industrial to post-industrial society as well as economic globalization, both of which have contributed to the growth and global expansion of the middle class, having thus fundamentally renovated the middle class.展开更多
s: Ultrafine A2La2Ti3O10 (A=K, Na) powders with laminar structure were successfully synthesized by citric acid sol-gel method using ANO3(A=K, Na)?La(NO3)3?Ti(OBu)4 and citric acid as starting precursors. The crystalli...s: Ultrafine A2La2Ti3O10 (A=K, Na) powders with laminar structure were successfully synthesized by citric acid sol-gel method using ANO3(A=K, Na)?La(NO3)3?Ti(OBu)4 and citric acid as starting precursors. The crystalline phase of A2La2Ti3O10 can be obtained by thermal decomposition of citrate complex precursors at a relatively low temperature of 800 ℃ (600 ℃ for A=Na), about 300 ℃(500 ℃ for A=Na) lower than that of conventional solid state reaction process. The properties of the citrate precursors and the calcined powders were characterized by Infrared spectroscopy (IR), X-ray diffraction (XRD), transmission electron microscopy (TEM), thermal-gravimetric-differential thermal analysis (TG-DTA), inductively coupled plasma (ICP) and Brunauer-Emmett-Teller (BET) techniques. Results show that the average size of A2La2Ti3O10 powders obtained by citric acid sol-gel route was reduced to 200 nm×250 nm and the specific surface area was up to 19 m2·g-1. At the same time, the product was with more regular morphological characteristics. The synthesis process and the formation of A2La2Ti3O10 were also discussed. The obtained A2La2Ti3O10 was found to be transformed from A2La2Ti3O9.5 during the formation process.展开更多
文摘In this in-depth exploration, I delve into the complex implications and costs of cybersecurity breaches. Venturing beyond just the immediate repercussions, the research unearths both the overt and concealed long-term consequences that businesses encounter. This study integrates findings from various research, including quantitative reports, drawing upon real-world incidents faced by both small and large enterprises. This investigation emphasizes the profound intangible costs, such as trade name devaluation and potential damage to brand reputation, which can persist long after the breach. By collating insights from industry experts and a myriad of research, the study provides a comprehensive perspective on the profound, multi-dimensional impacts of cybersecurity incidents. The overarching aim is to underscore the often-underestimated scope and depth of these breaches, emphasizing the entire timeline post-incident and the urgent need for fortified preventative and reactive measures in the digital domain.
文摘The presented paper is dedicated to a new ret-rospective view on the history of natural sci-ences in XX-XXI cc, partially including the sci-ence philosophy (mainly, the problems of the scientific realism, i.e. the correspondence of science to reality) and also a novel scheme for different classes of sciences with different ob-jects and paradigms. There are analyzed the chosen “great” and “grand” problems of phys-ics (including the comprehension of quantum mechanics, with a recently elaborated new chapter, connected with time as a quantum obs- ervable and time analysis of quantum processes) and also of natural sciences as a whole. The particular attention is paid to the interpretation questions and slightly to the aspects, inevitably connected with the world- views of the res- earchers (which do often constitute a part of the interpretation questions).
基金supported by Open Fund (CRI2012RCPS0152CN) of State Key Laboratory of Offshore Oil Exploitationthe National Science and Technology Major Project (2011ZX05024-004-01)
文摘Polymer flooding has been proven to effectively improve oil recovery in the Bohai Oil Field. However, due to high oil viscosity and significant formation heterogeneity, it is necessary to further improve the displacement effectiveness of polymer flooding in heavy oil reservoirs in the service life of offshore platforms. In this paper, the effects of the water/oil mobility ratio in heavy oil reservoirs and the dimensionless oil productivity index on polymer flooding effectiveness were studied utilizing rel- ative permeability curves. The results showed that when the water saturation was less than the value, where the water/oil mobility ratio was equal to 1, polymer flooding could effectively control the increase of fractional water flow, which meant that the upper limit of water/oil ratio suitable for polymer flooding should be the value when the water/oil mobility ratio was equal to 1. Mean while, by injecting a certain volume of water to create water channels in the reservoir, the polymer flooding would be the most effective in improving sweep efficiency, and lower the fractional flow of water to the value corresponding to △Jmax. Considering the service life of the platform and the polymer mobility control capacity, the best polymer injection timing for heavy oil reservoirs was optimized. It has been tested for reservoirs with crude oil viscosity of 123 and 70 mPa s, the optimum polymer flooding effec- tiveness could be obtained when the polymer floods were initiated at the time when the fractional flow of water were 10 % and 25 %, respectively. The injection timing range for polymer flooding was also theoretically analyzed for the Bohai Oil Field utilizing which provided methods for effectiveness. relative permeability curves, improving polymer flooding
文摘This paper formulates the light timing calculations for each interferometer arm;one that is parallel to the direction of motion of the interferometer through space and the other that is perpendicular. The calculations are done for a vacuum-mode interferometer and then for a gas-mode interferometer. The calculations show that no light timing difference is detectable in a vacuum-mode interferometer, but once an optical medium is present in the light path down the arms of the interferometer, this is no longer the case and a timing difference is detectable. Further to this, the timing equations obtained from the analysis are used to model the historical experiments of Michelson-Morley and Miller (Mt Wilson) and predictions are made by the model that accurately match the actual recorded results from those experiments. Thus, this timing analysis confirms that there is a light speed anisotropy in a reference frame that is moving through space, indicating the presence of a preferred Aether reference frame through which the Earth is moving.
文摘This paper examines how cybersecurity is developing and how it relates to more conventional information security. Although information security and cyber security are sometimes used synonymously, this study contends that they are not the same. The concept of cyber security is explored, which goes beyond protecting information resources to include a wider variety of assets, including people [1]. Protecting information assets is the main goal of traditional information security, with consideration to the human element and how people fit into the security process. On the other hand, cyber security adds a new level of complexity, as people might unintentionally contribute to or become targets of cyberattacks. This aspect presents moral questions since it is becoming more widely accepted that society has a duty to protect weaker members of society, including children [1]. The study emphasizes how important cyber security is on a larger scale, with many countries creating plans and laws to counteract cyberattacks. Nevertheless, a lot of these sources frequently neglect to define the differences or the relationship between information security and cyber security [1]. The paper focus on differentiating between cybersecurity and information security on a larger scale. The study also highlights other areas of cybersecurity which includes defending people, social norms, and vital infrastructure from threats that arise from online in addition to information and technology protection. It contends that ethical issues and the human factor are becoming more and more important in protecting assets in the digital age, and that cyber security is a paradigm shift in this regard [1].
文摘This is a Unified Field description based on the holographic Time Dilation Cosmology, TDC, model, which is an eternal continuum evolving forward in the forward direction of time, at the speed of light, c, at an invariant 1 s/s rate of time. This is the Fundamental Direction of Evolution, FDE. There is also an evolution down time dilation gradients, the Gravitational Direction of Evolution, GDE. These evolutions are gravity, which is the evolutionary force in time. Gravitational velocities are compensation for the difference in the rate of time, dRt, in a dilation field, and the dRtis equal to the compensatory velocity’s percentage of c, and is a measure of the force in time inducing the velocity. In applied force induced velocities, the dRt is a measure of the resistance in time to the induced velocity, which might be called “anti-gravity” or “negative gravity”. The two effects keep the continuum uniformly evolving forward at c. It is demonstrated that gravity is already a part of the electromagnetic field equations in way of the dRt element contained in the TDC velocity formula. Einstein’s energy formula is defined as a velocity formula and a modified version is used for charged elementary particle solutions. A time dilation-based derivation of the Lorentz force ties gravity directly to the electromagnetic field proving the unified field of gravity and the EMF. It is noted how we could possibly create gravity drives. This is followed by a discussion of black holes, proving supermassive objects, like massive black hole singularities, are impossible, and that black holes are massless Magnetospheric Eternally Collapsing Objects (MECOs) that are vortices in spacetime. .
文摘Apart from listening to the cry of a healthy newborn,it is the declaration by the attending paediatrician in the labour room that the child is normal which brings utmost joy to parents.The global incidence of children born with congenital anomalies has been reported to be 3%-6%with more than 90%of these occurring in low-and middle-income group countries.The exact percentages/total numbers of children requiring surgical treatment cannot be estimated for several reasons.These children are operated under several surgical disciplines,viz,paediatric-,plastic reconstructive,neuro-,cardiothoracic-,orthopaedic surgery etc.These conditions may be life-threatening,e.g.,trachea-oesophageal fistula,critical pulmonary stenosis,etc.and require immediate surgical intervention.Some,e.g.,hydrocephalus,may need intervention as soon as the patient is fit for surgery.Some,e.g.,patent ductus arteriosus need‘wait and watch’policy up to a certain age in the hope of spontaneous recovery.Another extremely important category is that of patients where the operative intervention is done based on their age.Almost all the congenital anomalies coming under care of a plastic surgeon are operated as elective surgery(many as multiple stages of correction)at appropriate ages.There are advantages and disadvantages of intervention at different ages.In this article,we present a review of optimal timings,along with reasoning,for surgery of many of the common congenital anomalies which are treated by plastic surgeons.Obstetricians,paediatricians and general practitioners/family physicians,who most often are the first ones to come across such children,must know to guide the parents appropriately and convincingly impress upon the them as to why their child should not be operated immediately and also the consequences of too soon or too late.
基金supported in part by the National Natural Science Foundation of China,No.81573644(to LMH),81573733(to SWX)the Tianjin 131 Innovative Team Project,China(to HW)+5 种基金the National Major Science and Technology Project of China,No.2012ZX09101201-004(to SWX)the Science and Technology Plan Project of Tianjin of China,No.16PTSYJC00120(to LMH)the Applied Foundation and Frontier Technology Research Program of Tianjin of China(General Project),No.14JCYBJC28900(to SXW)the National International Science and Technology Cooperation Project of China,No.2015DFA30430(to HW)the Key Program of the Natural Science Foundation of Tianjin of China,No.16ICZDJC36300(to HW)the Scientific Research and Technology Development Plan Project of Guangxi Zhuang Autonomous Region of China,No.14125008-2-5(to SXW)
文摘Shuxuetong injection composed of leech(Hirudo nipponica Whitman) and earthworm(Pheretima aspergillum) has been used for the clinical treatment of acute stroke for many years in China. However, the precise neuroprotective mechanism of Shuxuetong injection remains poorly understood. Here, cerebral microvascular endothelial cells(bEnd.3) were incubated in glucose-free Dulbecco's modified Eagle's medium containing 95% N_2/5% CO_2 for 6 hours, followed by high-glucose medium containing 95% O_2 and 5% CO_2 for 18 hours to establish an oxygen-glucose deprivation/reperfusion model. This in vitro cell model was administered Shuxuetong injection at 1/32, 1/64, and 1/128 concentrations(diluted 32-, 64-, and 128-times). Cell Counting Kit-8 assay was used to evaluate cell viability. A fluorescence method was used to measure lactate dehydrogenase, and a fluorescence microplate reader used to detect intracellular reactive oxygen species. A fluorescent probe was also used to measure mitochondrial superoxide production. A cell resistance meter was used to measure transepithelial resistance and examine integrity of monolayer cells. The fluorescein isothiocyanate-dextran test was performed to examine blood-brain barrier permeability. Real-time reverse transcription polymerase chain reaction was performed to analyze mRNA expression levels of tumor necrosis factor alpha, interleukin-1β, interleukin-6, and inducible nitric oxide synthase. Western blot assay was performed to analyze expression of caspase-3, intercellular adhesion molecule 1, vascular cell adhesion molecule 1, occludin, vascular endothelial growth factor, cleaved caspase-3, B-cell lymphoma 2, phosphorylated extracellular signal-regulated protein kinase, extracellular signal-regulated protein kinase, nuclear factor-κB p65, I kappa B alpha, phosphorylated I kappa B alpha, I kappa B kinase, phosphorylated I kappa B kinase, claudin-5, and zonula occludens-1. Our results show that Shuxuetong injection increases bEnd.3 cell viability and B-cell lymphoma 2 expression, reduces cleaved caspase-3 expression, inhibits production of reactive oxygen species and mitochondrial superoxide, suppresses expression of tumor necrosis factor alpha, interleukin-1β, interleukin-6, inducible nitric oxide synthase mRNA, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1, markedly increases transepithelial resistance, decreases blood-brain barrier permeability, upregulates claudin-5, occludin, and zonula occludens-1 expression, reduces nuclear factor-κB p65 and vascular endothelial growth factor expression, and reduces I kappa B alpha, extracellular signal-regulated protein kinase 1/2, and I kappa B kinase phosphorylation levels. Overall, these findings suggest that Shuxuetong injection has protective effects on brain microvascular endothelial cells after oxygen-glucose deprivation/reperfusion. Moreover, its protective effect is associated with reduction of mitochondrial superoxide production, inhibition of the inflammatory response, and inhibition of vascular endothelial growth factor, extracellular signal-regulated protein kinase 1/2, and the nuclear factor-κB p65 signaling pathway.
文摘The beneficial acclimation hypothesis (BAH) predicts that animals acclimated to a particular temperature have enhanced performance or fitness at that temperature in comparison with animals acclimated to other temperatures. The BAH has been tested by a variety of empirical examinations, and was rejected by some of them. In order to provide new evidences for the BAH, the effects of acute and acclimation temperature (AT) on locomotor performance of Macrobiotus hufelandi (Tardigrada: Macrobiotidae) were investigated. The tardigrades were collected from Nanwutai, Qinling Mountains which traverse from west to east in central China. The subjects were acclimated to either 2℃ or 22℃ for 2 weeks. The animal was transferred onto a frosted slide and allowed to walk freely at the performance temperature (PT) 2℃ or 22℃. Only one individual was tested per test bout, which lasted from three to five minutes. To avoid occurrence of thermal acclimation effect, the standard adaptation time was limited to 1.5 min. Each subject was tested for once at the same PT, and was tested only at one PT. A total of 25 individuals were tested and measured at the same PT. The locomotor performance of the animals was recorded with a digital video camera mounted on a microscope at 4×10 amplification and replayed on a PC. Every subject was identified. Walking speed (WS) and percentage of time moving (PTM) at both PTs (2℃ or 22℃) were selected as the rate parameters of locomotor performance. The two-way repeated measures ANOVA with a significance level of α= 0.05 and Duncan multiple range test were used to analyze the data. WS of the animals acclimated to and tested at the same temperatures was significantly faster than that for animals acclimated to and tested at the different temperatures, similarly, PTM of the animals acclimated to 22℃ and tested at 22℃ was significantly greater than PTM of animals acclimated to 22℃ and tested at 2℃, which indicated that the animals acclimated to a particular temperature have enhanced locomotor performance in that temperature relative to the animals acclimated to that temperature in other thermal environment. WS of the animals acclimated to 22℃ and tested at 22℃ was significantly faster than WS of animals acclimated to 2℃ and tested at 22℃, PTM of the animals acclimated to 22℃ and tested at 22℃ was significantly greater than PTM of animals acclimated to 2℃ and tested at 22℃. These results supported the BAH. It could be concluded that the PT and thermal acclimation as well as the interaction between the PT and AT significantly influence the locomotor performance of M.hufelandi, and that, despite the existence of a few results of this study that don’t support the BAH, some results of this study support for this hypothesis, and that the animals acclimated to a particular temperature have enhanced locomotor performance in that temperature relative to the animals acclimated to that temperature in other thermal environment, implying that any performance temperature that deviates from the acclimation temperature could cause the reduction of the walking speed which is closely related to the fitness of the M.hufelandi.
文摘The reform of the housing system in Shanghai has unexpectedly given rise to a self-governed property owners’ collective supervisory system, primarily in the form of Property Owners’ Supervisory Council (POSC), which has picked up some of the government’s administrative functions. Although this new, institutionalized management model has theoretically made democratic managerial participation at the grassroots level possible, it has brought about endless problems, overt and covert, shortly after its appearance, some of which are even alarming. A comprehensive analysis of the data collected over a long period of time has led to the conclusion that this system is a failure, attributable to the overt factor related to skills in reality and the covert “priori” factor that is masked by the former. The existence of such “priori” factor once again demonstrates the deep-rooted, traditional managerial logic: Positive operations is society need only to depend upon individuals’ unstable self-disciplined morality rather than to build a system. The current paper points out that any change in the socioeconomic structure that has long been subject to the power of politics is to inevitably incur a corresponding global structural accommodation, including politics itself. To respond to the two factors for the failure, system building in the two overlapping areas is a must.
文摘Optimal detection of liquid ionization calorimeter signal in experimental particle physics is considered. A few linear and nonlinear approaches for amplitude and arrival time estimation based on the χ2 function are compared in simulation considering the noise sample correlation introduced by the analog pulse shaper. The estimation bias of the first-order approximation, a.k.a linear optimal filtering, is studied and contrasted to those of the second-order as well as the exhaustive search. A gradient-descent technique is presented as an alternative to the exhaustive search with significantly reduced search time and computation complexity. Results from various pulse shapers including the CR-RC2, CR-RC3, and CR2-RC2 are also compared.
文摘The article hypothesizes that DE and DM (UCM) are a “Form of Motion of a Special Nature”, where “Form of Motion” means “Eternal Motion” as the power of dynamics of different levels and varying degrees of self-sufficiency, and by “Special Nature”, gravitational and two other properties of matter, “tied” to the “Eternal Movement” and completely dependent on it. Carriers of key properties of a “Special Nature” have been established: “0”-DE particles and “3”-DM particles (UDM). The unity of their inherent “motionally-gravitational” properties and the peculiarity of the relationship between “motion” and “gravity” are revealed: the higher the intensity of “Eternal Motion”, the stronger the gravitational properties of matter are manifested (and vice versa). The relationship of “time” with the “vibration frequency” and the “mass” of photons with the “degree of bonding and deformation properties of the field” is shown. The maximum level of gravity has been determined, which allows Nature to successfully create the Universe: such a landmark is the proximity to the property of the Primary Source—the “pure graviton” of the OSP space, the most powerful “motionally-gravitational” particle of the Universe. The reasons for the emergence of such an identity of the gravitational properties of particles with the indicators of a “pure graviton” are established: for “0”-DE particles, this is the acquisition of the function of “freedom of movement”;for “3”-DM particles (UDM), the creation of a special structure—a “double field” (“Main” and “Small”). The presence in the “double field” of specific “tools” for the creation of the worlds of the Universe—gravitational “waves” gives rise to impulses (shocks) of varying intensity and shape. A list of functions performed by “waves” in the “Main” and “Small” fields has been compiled. The specific conditions for the formation of “UDM Streams”, their transformation into a “Vortex” and, under the influence of a powerful Initial Impulse (push), sending them to the “place” of the creation of galaxies, are shown. It is suggested that there is a “Cycle of Matter in Nature” in the closed structure of our Universe due to the “work” of “waves” and the functioning of special “factories” in the form of exotic space objects—Black holes.
文摘The Magneto-acoustic Tomography with Current Injection (MAT-CI) is a new biological electrical impedance imaging technique that combines Electrical Impedance Tomography (EIT) with Ultrasonic Imaging (UI), which possesses the non-invasive and high-contrast of the EIT and the high-resolution of the UI. The MAT-CI is expected to acquire high quality image and embraces a wide application. Its principle is to put the conductive sample in the Static Magnetic Field(SMF) and inject a time-varying current, during which the SMF and the current interact and generate the Lorentz Force that inspire ultrasonic signal received by the ultrasonic transducers positioned around the sample. And then according to related reconstruction algorithm and ultrasonic signal, electrical conductivity image is obtained. In this paper, a forward problem mathematical model of the MAT-CI has been set up to deduce the theoretical equation of the electromagnetic field and solve the sound source distribution by Green’s function. Secondly, a sound field restoration by Wiener filtering and reconstruction of current density by time-rotating method have deduced the Laplace’s equation that caters to the current density to further acquire the electrical conductivity distribution image of the sample through iteration method. In the end, double-loop coils experiments have been conducted to verify its feasibility.
基金National Natural Science Foundation of China No.51976083 and the Qing Lan Project.
文摘In order to improve the performance of the rotary engine,this paper has designed a new type of dual-pit rotary engine combustion chamber structure,and compares the combustion and emission characteristics with the rotary engine with a traditional combustion chamber.The existence of the dual-pit combustion chamber strengthens the overall vortex intensity in the cylinder,effectively promotes the mixing process of fuel and air in the cylinder,the maximum combustion pressure in the cylinder increased by 8.6%,significantly increases the diffusion combustion speed,and significantly improves the dynamic performance of the rotary engine.On this basis,the effects of fuel injection timing parameters on fuel distribution,combustion and emission characteristics were studied.Fuel distribution is more even and dispersed during injection in the later stage of compression.When the fuel injection timing was 105°BTDC in the middle of the compression phase,the matching effect of fuel distribution law and ignition scheme was the best.When the injection timing was 75°BTDC and 85°BTDC in the late compression stage,the mass fraction of NOx remained at a low level.The correlation between soot generation and the change of fuel injection timing was weak.When the injection time was 85°BTDC,the soot generation remained at a relatively high level.
文摘The emergence of the middle class was closely related to the appearance of industrial society and its consequential constant changes in the social structure. Karl Marx and other theorists in the same camp were among the earliest scholars who discussed that topic. For a quite long period of time, the debate was mainly focused on the characteristics of the “new middle class.” The middle class, however, has undergone a categorical transformation from the old to the new middle-class, and furthermore, this transformation itself has signified the transition in social patterns from industrial to post-industrial society as well as economic globalization, both of which have contributed to the growth and global expansion of the middle class, having thus fundamentally renovated the middle class.
文摘s: Ultrafine A2La2Ti3O10 (A=K, Na) powders with laminar structure were successfully synthesized by citric acid sol-gel method using ANO3(A=K, Na)?La(NO3)3?Ti(OBu)4 and citric acid as starting precursors. The crystalline phase of A2La2Ti3O10 can be obtained by thermal decomposition of citrate complex precursors at a relatively low temperature of 800 ℃ (600 ℃ for A=Na), about 300 ℃(500 ℃ for A=Na) lower than that of conventional solid state reaction process. The properties of the citrate precursors and the calcined powders were characterized by Infrared spectroscopy (IR), X-ray diffraction (XRD), transmission electron microscopy (TEM), thermal-gravimetric-differential thermal analysis (TG-DTA), inductively coupled plasma (ICP) and Brunauer-Emmett-Teller (BET) techniques. Results show that the average size of A2La2Ti3O10 powders obtained by citric acid sol-gel route was reduced to 200 nm×250 nm and the specific surface area was up to 19 m2·g-1. At the same time, the product was with more regular morphological characteristics. The synthesis process and the formation of A2La2Ti3O10 were also discussed. The obtained A2La2Ti3O10 was found to be transformed from A2La2Ti3O9.5 during the formation process.