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Semantic model and optimization of creative processes at mathematical knowledge formation
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作者 Victor Egorovitch Firstov 《Natural Science》 2010年第8期915-922,共8页
The aim of this work is mathematical education through the knowledge system and mathematical modeling. A net model of formation of mathematical knowledge as a deductive theory is suggested here. Within this model the ... The aim of this work is mathematical education through the knowledge system and mathematical modeling. A net model of formation of mathematical knowledge as a deductive theory is suggested here. Within this model the formation of deductive theory is represented as the development of a certain informational space, the elements of which are structured in the form of the orientated semantic net. This net is properly metrized and characterized by a certain system of coverings. It allows injecting net optimization parameters, regulating qualitative aspects of knowledge system under consideration. To regulate the creative processes of the formation and realization of mathematical know- edge, stochastic model of formation deductive theory is suggested here in the form of branching Markovian process, which is realized in the corresponding informational space as a semantic net. According to this stochastic model we can get correct foundation of criterion of optimization creative processes that leads to “great main points” strategy (GMP-strategy) in the process of realization of the effective control in the research work in the sphere of mathematics and its applications. 展开更多
关键词 The Cybernetic Conception Optimization of CONTROL Quantitative And Qualitative Information Measures Modelling Intellectual Systems Neural Network MATHEMATICAL Education The CONTROL of Pedagogical processES CREATIVE Pedagogics Cognitive And CREATIVE processES Informal Axiomatic Thery SEMANTIC NET NET Optimization Parameters The Topology of SEMANTIC NET Metrization The System of Coverings Stochastic Model of CREATIVE processES At The Formation of MATHEMATICAL Knowledge Branching Markovian process Great Main Points Strategy (GMP-Strategy) of The CREATIVE processES CONTROL Interdisciplinary Learning: Colorimetric Barycenter
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A Workable Solution for Reducing the Large Number of Vehicle and Pedestrian Accidents Occurring on a Yellow Light
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作者 Pranav Gupta Silki Arora 《Journal of Transportation Technologies》 2024年第1期82-87,共6页
Traffic intersections are incredibly dangerous for drivers and pedestrians. Statistics from both Canada and the U.S. show a high number of fatalities and serious injuries related to crashes at intersections. In Canada... Traffic intersections are incredibly dangerous for drivers and pedestrians. Statistics from both Canada and the U.S. show a high number of fatalities and serious injuries related to crashes at intersections. In Canada, during 2019, the National Collision Database shows that 28% of traffic fatalities and 42% of serious injuries occurred at intersections. Likewise, the U.S. National Highway Traffic Administration (NHTSA) found that about 40% of the estimated 5,811,000 accidents in the U.S. during the year studied were intersection-related crashes. In fact, a major survey by the car insurance industry found that nearly 85% of drivers could not identify the correct action to take when approaching a yellow traffic light at an intersection. One major reason for these accidents is the “yellow light dilemma,” the ambiguous situation where a driver should stop or proceed forward when unexpectedly faced with a yellow light. This situation is even further exacerbated by the tendency of aggressive drivers to inappropriately speed up on the yellow just to get through the traffic light. A survey of Canadian drivers conducted by the Traffic Injury Research Foundation found that 9% of drivers admitted to speeding up to get through a traffic light. Another reason for these accidents is the increased danger of making a left-hand turn on yellow. According to the National Highway Traffic Safety Association (NHTSA), left turns occur in approximately 22.2% of collisions—as opposed to just 1.2% for right turns. Moreover, a study by CNN found left turns are three times as likely to kill pedestrians than right turns. The reason left turns are so much more likely to cause an accident is because they take a driver against traffic and in the path of oncoming cars. Additionally, most of these left turns occur at the driver’s discretion—as opposed to the distressingly brief left-hand arrow at busy intersections. Drive Safe Now proposes a workable solution for reducing the number of accidents occurring during a yellow light at intersections. We believe this fairly simple solution will save lives, prevent injuries, reduce damage to public and private property, and decrease insurance costs. 展开更多
关键词 Traffic Accidents Yellow Light Traffic Light Signals INTERSECTION Crashes Collision Traffic Fatalities Traffic Injuries Vehicles SAFETY Speed Limit Driving Pedestrians Bicyclists MOTORCYCLISTS Caution Line Yellow Light Dilemma Left Hand Turn on Yellow Distance Smart Road Technology Signs Signage Autonomous Vehicles AVs Road Safety IoT Internet of Things Infrastructure Accident Reduction Driving Habits Stop Line Red Light Jumping Pedestrian Safety Caution Light Stopping at Intersection Safety at Intersections
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Structures and Properties of Iron Matrix Composites with Tungsten Carbide Particle by EPC-V Process 被引量:5
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作者 Xu Daqing Luo Jirong Huang Naiyu 《Journal of Iron and Steel Research(International)》 SCIE EI CAS CSCD 1999年第2期29-32,共4页
In this paper the Expendable Pattern Casting with dry sand Vacuum(EPC-V) process is used to manufacture iron matrix composites with tungsten carbide particle.Microstructures of the composites layers were analyzed.The ... In this paper the Expendable Pattern Casting with dry sand Vacuum(EPC-V) process is used to manufacture iron matrix composites with tungsten carbide particle.Microstructures of the composites layers were analyzed.The abrasive wear resistance of the composites layers were tested and compared with that of high chromium cast iron.The results show that the iron matrix composites with tungsten carbide particle have high hardness.The abrasive wear resistance of composites with tungsten carbide particle is higher than that of high chromium cast iron.The properties of the matrix materials have been improved remarkably. 展开更多
关键词 ABSTRACT:In this paper the Expendable Pattern Casting with dry sand Vacuum (EPC V) process is used to manufacture iron matrix COMPOSITES with TUNGSTEN CARBIDE particle. Microstructures of the COMPOSITES layers were analyzed. The ABRASIVE wear
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Research on Technological Process Control Model of Reverse Logistics in Manufacturing System 被引量:1
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作者 CHANG Jiane,LIU Chao (School of Electromechanical Engineering,Wuhan University of Technology, Wuhan 430070,China) 《武汉理工大学学报》 CAS CSCD 北大核心 2006年第S1期275-279,共5页
This paper has found out some important input factors of reverse logistics in manufacturing system throuth analysis and summary,and established four kinds of technological process control models of reverse logistics i... This paper has found out some important input factors of reverse logistics in manufacturing system throuth analysis and summary,and established four kinds of technological process control models of reverse logistics in manufacturing system according to different processing methods. These models embed each other that form a cubic control system of reverse logistics. 展开更多
关键词 MANUFACTURING system REVERSE LOGISTICS technological process CONTROL model
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The Application of Air-flow to the Technological Process of Chemical Fiber
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作者 崔启亮 陈明 《Journal of China Textile University(English Edition)》 EI CAS 1999年第3期112-114,共3页
The air-flow’s states and ways acted on the technological process of chemical fiber are summed up, which includes chip drying, spinning quenching as well as airjet texturing (air texturing, tangling texturing and bul... The air-flow’s states and ways acted on the technological process of chemical fiber are summed up, which includes chip drying, spinning quenching as well as airjet texturing (air texturing, tangling texturing and bulked continuous filament (BCF)),and the effect of air-flow on the process and quality of chemical fiber is studied,and the action of mechanics and heat on the bulked continuous filament are calculated. 展开更多
关键词 AIR - flow CHEMICAL FIBER technological process
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Unlocking the Potential:A Comprehensive Systematic Review of ChatGPT in Natural Language Processing Tasks
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作者 Ebtesam Ahmad Alomari 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第10期43-85,共43页
As Natural Language Processing(NLP)continues to advance,driven by the emergence of sophisticated large language models such as ChatGPT,there has been a notable growth in research activity.This rapid uptake reflects in... As Natural Language Processing(NLP)continues to advance,driven by the emergence of sophisticated large language models such as ChatGPT,there has been a notable growth in research activity.This rapid uptake reflects increasing interest in the field and induces critical inquiries into ChatGPT’s applicability in the NLP domain.This review paper systematically investigates the role of ChatGPT in diverse NLP tasks,including information extraction,Name Entity Recognition(NER),event extraction,relation extraction,Part of Speech(PoS)tagging,text classification,sentiment analysis,emotion recognition and text annotation.The novelty of this work lies in its comprehensive analysis of the existing literature,addressing a critical gap in understanding ChatGPT’s adaptability,limitations,and optimal application.In this paper,we employed a systematic stepwise approach following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)framework to direct our search process and seek relevant studies.Our review reveals ChatGPT’s significant potential in enhancing various NLP tasks.Its adaptability in information extraction tasks,sentiment analysis,and text classification showcases its ability to comprehend diverse contexts and extract meaningful details.Additionally,ChatGPT’s flexibility in annotation tasks reducesmanual efforts and accelerates the annotation process,making it a valuable asset in NLP development and research.Furthermore,GPT-4 and prompt engineering emerge as a complementary mechanism,empowering users to guide the model and enhance overall accuracy.Despite its promising potential,challenges persist.The performance of ChatGP Tneeds tobe testedusingmore extensivedatasets anddiversedata structures.Subsequently,its limitations in handling domain-specific language and the need for fine-tuning in specific applications highlight the importance of further investigations to address these issues. 展开更多
关键词 Generative AI large languagemodel(LLM) natural language processing(NLP) ChatGPT GPT(generative pretraining transformer) GPT-4 sentiment analysis NER information extraction ANNOTATION text classification
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A retrospective view on the history of natural sciences in XX-XXI
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作者 Vladislav Sergeyevich Olkhovsky 《Natural Science》 2010年第3期228-245,共18页
The presented paper is dedicated to a new ret-rospective view on the history of natural sci-ences in XX-XXI cc, partially including the sci-ence philosophy (mainly, the problems of the scientific realism, i.e. the cor... The presented paper is dedicated to a new ret-rospective view on the history of natural sci-ences in XX-XXI cc, partially including the sci-ence philosophy (mainly, the problems of the scientific realism, i.e. the correspondence of science to reality) and also a novel scheme for different classes of sciences with different ob-jects and paradigms. There are analyzed the chosen “great” and “grand” problems of phys-ics (including the comprehension of quantum mechanics, with a recently elaborated new chapter, connected with time as a quantum obs- ervable and time analysis of quantum processes) and also of natural sciences as a whole. The particular attention is paid to the interpretation questions and slightly to the aspects, inevitably connected with the world- views of the res- earchers (which do often constitute a part of the interpretation questions). 展开更多
关键词 SCIENCE history SCIENCE realism paradigm PROBLEM of interpretation and comprehension of QUANTUM mechanics the WAVE-FUNCTION collapse the Einstein-Podolsky-Rosen paradox TIME as a QUANTUM observable canonically conjugated to energy maximal hermitian TIME operator TIME analysis of QUANTUM processes relationship be-tween physics and biology PROBLEM of origin of biologic life REDUCTIONISM cosmologic PROBLEM Big Bang anthropic principle
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TLC Identification and Extraction Process of Rubiasin-1-methyl Ether from Yao Medicine Chuanlianzhu
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作者 Jingrong LU Jiangcun WEI +3 位作者 Xiumei MA Bing QING Meiyan QIU Wen ZHONG 《Medicinal Plant》 2024年第3期35-38,共4页
[Objectives]To establish a thin-layer chromatography(TLC)method for the determination of rubiadin-1-methyl ether in Yao Medicine Chuanlianzhu(Damnacanthus giganteus).[Methods]A silica gel G thin-layer plate was adopte... [Objectives]To establish a thin-layer chromatography(TLC)method for the determination of rubiadin-1-methyl ether in Yao Medicine Chuanlianzhu(Damnacanthus giganteus).[Methods]A silica gel G thin-layer plate was adopted for TLC.Petroleum ether(60-90℃)-chloroform-methanol-water(7:15:3:1)was used as the developing solvent and inspected under ultraviolet lamp(365 nm).The content was determined by Inertsil ODS-3 C 18 column(4.60 mm×250 mm,5μm),mobile phase:acetonitrile-0.2%phosphoric acid gradient elution,detection wavelength 277 nm,flow rate 1.0 mL/min,column temperature 30℃,injection volume 10μL.[Results]The spots of 10 Chuanlianzhu samples from different origins showed the same color at the same position as the control,and the spots were clear and specific.The injection volume of rubiadin-1-methyl ether showed a good linear relationship in the range of 2.90-145μg(R=0.9996).The average recovery rate of rubiadin-1-methyl ether in the low,medium and high dose groups of Yao Medicine Chuanlianzhu was 98.72%,and RSD=1.78%.[Conclusions]This method can effectively identify Yao Medicine Chuanlianzhu medicinal materials and accurately determine the content of rubiadin-1-methyl ether in the medicinal materials.It provides a scientific basis for the development and utilization of Yao Medicine Chuanlianzhu medicinal resources. 展开更多
关键词 Chuanlianzhu THIN-LAYER chromatography (TLC) Extraction process Rubiadin-1-methyl ETHER Content determination
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他们不再是孩子了 关于“新失业群体”现状的社会学报告 被引量:26
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作者 吕鹏 《社会》 北大核心 2005年第4期119-142,共24页
The “New Unemployed” consists of young people with low education in the Chinese cities. They differ from the cohorts of their parents because they have no work experiences in any state- or collective-owned enterpris... The “New Unemployed” consists of young people with low education in the Chinese cities. They differ from the cohorts of their parents because they have no work experiences in any state- or collective-owned enterprise, and are subject to completely different policies designated by the government. Investigations of their daily living lead to the conclusion that the “New Unemployed” has gone through a “system withdrawal” process. They are now facing an environment of “system vacuum” that none of other unemployed groups has ever encountered before. The author emphasizes in the paper a strategic employment principle of “For Future Generations” so that focused attention and care can be provided and this toughest challenge in China can be dealt with. 展开更多
关键词 enterprise system Chinese because process people that before with other China and from have work GONE NONE ever care this The New has can of any For to so
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Trust beyond Technology Algorithms: A Theoretical Exploration of Consumer Trust and Behavior in Technological Consumption and AI Projects
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作者 David Oyekunle Ugochukwu Okwudili Matthew +1 位作者 David Preston David Boohene 《Journal of Computer and Communications》 2024年第6期72-102,共31页
In an era dominated by artificial intelligence (AI), establishing customer confidence is crucial for the integration and acceptance of AI technologies. This interdisciplinary study examines factors influencing custome... In an era dominated by artificial intelligence (AI), establishing customer confidence is crucial for the integration and acceptance of AI technologies. This interdisciplinary study examines factors influencing customer trust in AI systems through a mixed-methods approach, blending quantitative analysis with qualitative insights to create a comprehensive conceptual framework. Quantitatively, the study analyzes responses from 1248 participants using structural equation modeling (SEM), exploring interactions between technological factors like perceived usefulness and transparency, psychological factors including perceived risk and domain expertise, and organizational factors such as leadership support and ethical accountability. The results confirm the model, showing significant impacts of these factors on consumer trust and AI adoption attitudes. Qualitatively, the study includes 35 semi-structured interviews and five case studies, providing deeper insight into the dynamics shaping trust. Key themes identified include the necessity of explainability, domain competence, corporate culture, and stakeholder engagement in fostering trust. The qualitative findings complement the quantitative data, highlighting the complex interplay between technology capabilities, human perceptions, and organizational practices in establishing trust in AI. By integrating these findings, the study proposes a novel conceptual model that elucidates how various elements collectively influence consumer trust in AI. This model not only advances theoretical understanding but also offers practical implications for businesses and policymakers. The research contributes to the discourse on trust creation and decision-making in technology, emphasizing the need for interdisciplinary efforts to address societal challenges associated with technological advancements. It lays the groundwork for future research, including longitudinal, cross-cultural, and industry-specific studies, to further explore consumer trust in AI. 展开更多
关键词 Consumer Trust AI-Driven Projects TRANSPARENCY Ethical Accountability Structural Equation Modeling (SEM) Technology Acceptance Model (TAM) Interdisciplinary Study Organizational Factors Psychological Factors Behavioral Intention
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Analytic Hierarchy Process for Technological Risks in the Process of Innovative Drug Development in China
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作者 Diao Yuanyuan Wu Zhiang 《Asian Journal of Social Pharmacy》 2024年第1期29-42,共14页
Objective To identify the critical risks in the process of innovative drug research and development,and to provide reference for improving the efficiency of innovative drug development and risk control in China.Method... Objective To identify the critical risks in the process of innovative drug research and development,and to provide reference for improving the efficiency of innovative drug development and risk control in China.Methods Expert investigation and analytic hierarchy process were used to determine the weights of different risks.Results and Conclusion The research and analysis results showed that the risks at different stages of development had different effects on the success rate of drug development,among which the risk at the drug discovery stage influenced the most.In the drug discovery stage,inappropriate target selection had the greatest impact on the success rate of drug development.The lack of appropriate cell tissue or animal models had the greatest impact on the success rate of drug development from the discovery of a compound to the application for clinical trials.The difference in changes between nonclinical and clinical studies had the greatest impact on the success rate of drug development from early clinical studies to pivotal clinical studies.Incorrect dose selection had the greatest impact on the success rate of drug development from pivotal clinical studies to marketing authorization applications.The biggest impact from the marketing authorization application to the approval stage was inadequate communication with regulators.After investigating the weight of risk factors in the process of innovative drug development based on scientific methods,a new perspective for the risk control of new drug development and improving the research and development efficiency is provided. 展开更多
关键词 innovative drug drug research and development risk management analytic hierarchy process WEIGHT
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Applications of Mogulskii, and Kurtz-Feng Large Deviation Results to Risk Reserve Processes with Aggregate Claims
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作者 Jorge Garcia Ana Meda 《Applied Mathematics》 2012年第12期2109-2117,共9页
In this paper we examine the large deviations principle (LDP) for sequences of classic Cramér-Lundberg risk processes under suitable time and scale modifications, and also for a wide class of claim distributions ... In this paper we examine the large deviations principle (LDP) for sequences of classic Cramér-Lundberg risk processes under suitable time and scale modifications, and also for a wide class of claim distributions including (the non-super- exponential) exponential claims. We prove two large deviations principles: first, we obtain the LDP for risk processes on D∈[0,1] with the Skorohod topology. In this case, we provide an explicit form for the rate function, in which the safety loading condition appears naturally. The second theorem allows us to obtain the LDP for Aggregate Claims processes on D∈[0,∞) with a different time-scale modification. As an application of the first result we estimate the ruin probability, and for the second result we work explicit calculations for the case of exponential claims. 展开更多
关键词 Large Deviations Cramer-Lundberg Reserve Risk processES Probability Theory and Mathematical Statistics in INSURANCE Stochastic Models for CLAIM Frequency CLAIM Size and Aggregate CLAIMS RESERVES
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Depositional process of hyperpycnal flow deposits:A case study on Lower Cretaceous Sangyuan outcrop in the Luanping Basin,Northeast China
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作者 De-zhi Yan Ru-kai Zhu +8 位作者 Hao Shou Zhao-hui Xu Wei-hong Liu Si-cheng Zhu Zhi-cheng Lei Jing-ya Zhang Chang Liu Yi Cai Huai-min Xu 《China Geology》 CAS CSCD 2024年第3期505-516,共12页
Sedimentary process research is of great significance for understanding the distribution and characteristics of sediments.Through the detailed observation and measurement of the Sangyuan outcrop in Luanping Basin,this... Sedimentary process research is of great significance for understanding the distribution and characteristics of sediments.Through the detailed observation and measurement of the Sangyuan outcrop in Luanping Basin,this paper studies the depositional process of the hyperpycnal flow deposits,and divides their depositional process into three phases,namely,acceleration,erosion and deceleration.In the acceleration phase,hyperpycnal flow begins to enter the basin nearby,and then speeds up gradually.Deposits developed in the acceleration phase are reverse.In addition,the original deposits become unstable and are taken away by hyperpycnal flows under the eroding force.As a result,there are a lot of mixture of red mud pebbles outside the basin and gray mud pebbles within the basin.In the erosion phase,the reverse deposits are eroded and become thinner or even disappear.Therefore,no reverse grading characteristic is found in the proximal major channel that is closer to the source,but it is still preserved in the middle branch channel that is far from the source.After entering the deceleration phase,normally grading deposits appear and cover previous deposits.The final deposits in the basin are special.Some are reverse,and others are normal.They are superimposed with each other under the action of hyperpycnal flow.The analysis of the Sangyuan outcrop demonstrates the sedimentary process and distribution of hyperpycnites,and reasonably explain the sedimentary characteristics of hyperpycnites.It is helpful to the prediction of oil and gas exploration targets in gravity flow deposits. 展开更多
关键词 Hyperpycnal flow Sedimentary characteristics Depositional process Gravity flow deposit Hyperpycnite Red mud pebble Gray mud pebble Oil and gas exploration engineering Luanping Basin
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Applications of advanced signal processing and machine learning in the neonatal hypoxic-ischemic electroencephalography 被引量:4
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作者 Hamid Abbasi Charles P.Unsworth 《Neural Regeneration Research》 SCIE CAS CSCD 2020年第2期222-231,共10页
Perinatal hypoxic-ischemic-encephalopathy significantly contributes to neonatal death and life-long disability such as cerebral palsy. Advances in signal processing and machine learning have provided the research comm... Perinatal hypoxic-ischemic-encephalopathy significantly contributes to neonatal death and life-long disability such as cerebral palsy. Advances in signal processing and machine learning have provided the research community with an opportunity to develop automated real-time identification techniques to detect the signs of hypoxic-ischemic-encephalopathy in larger electroencephalography/amplitude-integrated electroencephalography data sets more easily. This review details the recent achievements, performed by a number of prominent research groups across the world, in the automatic identification and classification of hypoxic-ischemic epileptiform neonatal seizures using advanced signal processing and machine learning techniques. This review also addresses the clinical challenges that current automated techniques face in order to be fully utilized by clinicians, and highlights the importance of upgrading the current clinical bedside sampling frequencies to higher sampling rates in order to provide better hypoxic-ischemic biomarker detection frameworks. Additionally, the article highlights that current clinical automated epileptiform detection strategies for human neonates have been only concerned with seizure detection after the therapeutic latent phase of injury. Whereas recent animal studies have demonstrated that the latent phase of opportunity is critically important for early diagnosis of hypoxic-ischemic-encephalopathy electroencephalography biomarkers and although difficult, detection strategies could utilize biomarkers in the latent phase to also predict the onset of future seizures. 展开更多
关键词 advanced signal processing AEEG automatic detection classification clinical EEG fetal HIE hypoxic-ischemic ENCEPHALOPATHY machine learning neonatal SEIZURE real-time identification review
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9个不同使用类型木薯品系在合浦县的适应性研究
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作者 罗燕春 赵鑫鑫 +8 位作者 盘欢 廖琦 俞奔驰 劳赏业 范锡恩 刘翠娟 李荣云 曾新华 付海天 《中国农学通报》 2024年第18期31-37,共7页
为筛选适宜在合浦县推广的木薯品系,本研究以主栽品种‘南植199’为对照,对9个木薯新品系的生物学特性进行了观察,并测定其农艺性状和经济性状,同时进行相关性分析。结果表明,9个品系分枝角度小、块根长度适中和主茎高度中等以上;‘RC4... 为筛选适宜在合浦县推广的木薯品系,本研究以主栽品种‘南植199’为对照,对9个木薯新品系的生物学特性进行了观察,并测定其农艺性状和经济性状,同时进行相关性分析。结果表明,9个品系分枝角度小、块根长度适中和主茎高度中等以上;‘RC4’的块根产量显著高于对照,其余8个品系与对照差异不显著;‘RC4’等8个品系的淀粉产量高于对照;9个品系的淀粉含量高于对照,其中‘RC3’等5个品系的淀粉含量显著或极显著高于对照;9个木薯品系的直链淀粉含量显著或极显著低于对照‘;RC6’等6个品系的氢氰酸含量低于50 mg/kg。相关性分析结果表明:块根产量与生长中期株高、成熟期株高、块根直径呈极显著正相关,与茎粗呈显著正相关;淀粉含量与生长中期株高、成熟期株高、茎粗呈显著正相关;淀粉产量与生长中期株高、成熟期株高、茎粗、块根直径、块根产量呈极显著正相关,与淀粉含量呈显著正相关。综合来看,这9个木薯新品系的综合表现良好,适合在合浦县进行推广。其中‘,RC3’、‘RC4’和‘RC7’可作为加工型品系;‘RC5’和‘RC10’可作为食用品系;‘RC2’、‘RC6’、‘RC11’和‘RC12’可作为鲜食加工兼用品系;‘RC2’和‘RC5’作为食用品系具有很好的推广前景。 展开更多
关键词 使 广
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Genomic Instability in Cancer II: 4N-Skewed (90°) Reductive Division via Fragile Sites to Fitness Increase for Solid and Hematological Cancer Beginnings 被引量:2
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作者 Kirsten H. Walen 《Journal of Cancer Therapy》 2019年第7期537-564,共28页
The objective herein was to connect the ontogeny process of diplochromosomal, amitotic, 4n-skewed division-system, to cytogenetic deficiency lesions in satellite, repetitive DNAs, especially in the chromosomal fragile... The objective herein was to connect the ontogeny process of diplochromosomal, amitotic, 4n-skewed division-system, to cytogenetic deficiency lesions in satellite, repetitive DNAs, especially in the chromosomal fragile sites, some 100 distributed over the genome. These latter studies had shown that chemical induced replication-stress led to un-replicated lesions in these fragile sites, which from inaccurate repair processes caused genomic instability. In the chain of events of the ontogeny process to the special tetraploidy, it was proposed that primary damaged human cells could undergo replication stress from repair-process present during cell replication, a suggestion verified by X-ray damaged cells producing the unstable fragile sites (see text). The cancer-importance for therapy is recognition of cell cycle change for the 4n derivative fitness-gained, diploid progeny cells. An open question is whether RB controlling G1 to S-period is mutated at this suggested tumorigenesis initiating phase, and if so, with what consequences for therapy. The fragile site studies further showed that repair of repetitive DNAs could produce two types of genomic changes: single gene mutations and CNVs, which were here shown to be chromosomally located on “borders” to repairing satellite lesions. This genomic placement was found to correspond to mutations identified in tumor sequencing (p53, Rb, MYC), favoring a bad luck location for their cancer “mutational nature”. The CNVs in cancers, are here seen as molecular expressions of long-known cytogenetic HSRs and DMs also with demonstrated origin from amplifications of single genes. Over-expression of oncogenes was hinted of being from duplications, but Drosophila genetics demonstrated the opposite, gene inactivation. The reduced eye-size from dominant, BAR-Ultra-Bar-eye phenotypes, was caused by duplications, inactivating the genetic system for eye-size. The finding of CNVs showing “evasion” of the immune system suggests, inactivation of immune-determining genetics. Since mutated genes on borders to satellite DNAs are a fact in hematological cancers, the 4n-skewed division-system is suggested to replace debated leukemogenesis with fitness-gain from molecular mutations. For these cancers the question is how normal bone marrow cells attain genomic damage for special tetraploidy, which was referred to studies of cells moving in artificial marrow-like substrate, needing serious attention. 展开更多
关键词 Centrifugal 90° Turn CENTROSOME Absence Mitotic Slippage process Diplochromosomes Mutator Mechanism Satellite DNA MUTATIONS Fragile Site Instability Repair MUTATIONS Copy Number Variants CHROMOSOME Nuclear Domains HEMATOLOGIC TRANSLOCATIONS Density Bone Marrow Substrate Abnormal Laminar Proteins Chromosome/Gene UPD Haplo-Insufficiency
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Solid-state impedance spectroscopy studies of dielectric properties and relaxation processes in Na_(2)O–V_(2)O_(5)–Nb_(2)O_(5)–P_(2)O_(5) glass
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作者 Sara Marijan Luka Pavic 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CSCD 2024年第1期186-196,共11页
Solid-state impedance spectroscopy(SS-IS)was used to investigate the influence of structural modifications resulting from the addition of Nb2O5 on the dielectric properties and relaxation processes in the quaternary m... Solid-state impedance spectroscopy(SS-IS)was used to investigate the influence of structural modifications resulting from the addition of Nb2O5 on the dielectric properties and relaxation processes in the quaternary mixed glass former(MGF)system 35Na_(2)O–10V_(2)O_(5)–(55-x)P_(2)O_(5)–xNb_(2)O_(5)(x=0–40,mol%).The dielectric parameters,including the dielectric strength and dielectric loss,are determined from the frequency and temperature-dependent complex permittivity data,revealing a significant dependence on the Nb2O5 content.The transition from a predominantly phosphate glass network(x<10,region I)to a mixed niobate–phosphate glass net-work(10≤x≤20,region II)leads to an increase in the dielectric parameters,which correlates with the observed trend in the direct-cur-rent(DC)conductivity.In the predominantly niobate network(x≥25,region III),the highly polarizable nature of Nb5+ions leads to a fur-ther increase in the dielectric permittivity and dielectric strength.This is particularly evident in Nb-40 glass-ceramic,which contains Na_(13)Nb_(35)O_(94) crystalline phase with a tungsten bronze structure and exhibits the highest dielectric permittivity of 61.81 and the lowest loss factor of 0.032 at 303 K and 10 kHz.The relaxation studies,analyzed through modulus formalism and complex impedance data,show that DC conductivity and relaxation processes are governed by the same mechanism,attributed to ionic conductivity.In contrast to glasses with a single peak in frequency dependence of imaginary part of electrical modulus,M″(ω),Nb-40 glass-ceramic exhibits two distinct contributions with similar relaxation times.The high-frequency peak indicates bulk ionic conductivity,while the additional low-fre-quency peak is associated with the grain boundary effect,confirmed by the electrical equivalent circuit(EEC)modelling.The scaling characteristics of permittivity and conductivity spectra,along with the electrical modulus,validate time-temperature superposition and demonstrate a strong correlation with composition and modification of the glass structure upon Nb_(2)O_(5) incorporation. 展开更多
关键词 phosphate glasses GLASS-CERAMICS impedance spectroscopy dielectric properties relaxation processes permittivity scaling conductivity scaling modulus formalism
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GIS Based Landslide Susceptibility Mapping with Application of Analytical Hierarchy Process in District Ghizer, Gilgit Baltistan Pakistan 被引量:3
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作者 Irum Rahim Syeda Maria Ali Maria Aslam 《Journal of Geoscience and Environment Protection》 2018年第2期34-49,共16页
District Ghizer is a rugged mountainous territory which experiences several landslides each year. There are 16 major landslide areas and 53 villages that are at high risk to hazards. Keeping in view the severity of na... District Ghizer is a rugged mountainous territory which experiences several landslides each year. There are 16 major landslide areas and 53 villages that are at high risk to hazards. Keeping in view the severity of natural hazards, the present study was designed to generate landslide susceptibility map based on twelve causative factors viz., slope, aspect, elevation, drainage network, Stream Power Index (SPI), Topographic Wetness Index (TWI), lithological units, fault lines, rainfall, road network, land cover and soil texture. Soil texture was determined by particle size analysis and data for other factors were acquired from freely available sources. Analytical Hierarchy Process (AHP) was employed to identify major landslide causative factors in the district Ghizer. Further, a temporal assessment from 1999 till 2015 was generated to assess the impact of land cover change on landslides. It indicated that the barren soil/ exposed rocks and glaciers have reduced while the vegetation and water classes have shown increment. The total area that lies in moderate to very high landslide susceptible zones was 74.38%, while slope is the main landslide causative factor in the district Ghizer. Validation of the susceptibility map showed 88.1% of the landslides in the study area had occurred in the moderate to very high susceptible zones. 展开更多
关键词 LANDSLIDE SUSCEPTIBILITY Mapping (LSM) Analytical HIERARCHY process (AHP) GEOGRAPHIC Information System (GIS) Weighted Linear Combination (WLC) Remote Sensing (RS)
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Fundamentals on Thermodynamic Processes behind Clouds’ and Rainfalls’ Formation
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作者 Mbane Biouele César 《Atmospheric and Climate Sciences》 2015年第3期257-265,共9页
The prevailing idea so far about why the rainfall occurs was that after agglutination of water droplets with condensation nuclei, the size of the particle formed by the condensation nuclei connected with droplets of w... The prevailing idea so far about why the rainfall occurs was that after agglutination of water droplets with condensation nuclei, the size of the particle formed by the condensation nuclei connected with droplets of water increased considerably and caused its fall. This idea has led to numerous scientific publications in which empirical distribution functions of clouds’ water droplets sizes were proposed. Estimates values provided by these empirical distribution functions, in most cases, were validated by comparison with UHF Radar measurements. The condensation nuclei concept has not been sufficiently exploited and this has led meteorologists to error, in their attempt to describe the clouds, thinking that clouds were formed by liquid water droplets. Indeed, MBANE BIOUELE paradox (2005) confirms this embarrassing situation. In fact, when applying Archimedes theorem to a liquid water droplet suspended in the atmosphere, we obtain a meaningless inequality ?which makes believe that the densities of pure water in liquid and solid phases are much lower than that of the atmosphere considered at the sea level. This meaningless inequality is easy to contradict: of course, if you empty a bottle of pure liquid water in the ocean (where z is equal to 0), this water will not remain suspended in the air, i.e., application of Archimedes’ theorem allows realizing that there is no liquid (or solid) water droplet, suspended in the clouds. Indeed, all liquid (or solid) water droplets which are formed in clouds, fall under the effect of gravity and produce rains. This means that our current description of the clouds is totally wrong. In this study, we describe the clouds as a gas composed of dry air and saturated water vapor whose optical properties depend on temperature, i.e., when the temperature of a cloud decreases, the color of this gaseous system tends towards white. 展开更多
关键词 Condensation nuclei Clouds FORMATION THERMODYNAMIC processes MBANE BIOUELE PARADOX CLOUDS CANNOT Be Composed of Suspended Liquid (or Solid) Water Droplets
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A fast method to diagnose phase transition from amorphous to microcrystalline silicon 被引量:4
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作者 HOU GuoFu1,2,3,XUE JunMing1,2,3,YUAN YuJie1,2,3,SUN Jian1,2,3,ZHAO Ying1,2,3 & GENG XinHua1,2,3 1 Institute of Photoelectronics,Nankai University,Tianjin 300071,China 2 Tianjin Key Laboratory of Photoelectronic Thin Film Devices and Technique,Tianjin 300071,China 3 Key Laboratory of Optoelectronic Information Science and Technology of Ministry of Education of China,Tianjin 300071,China 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS 2007年第6期731-736,共6页
A series of hydrogenated silicon thin films were prepared by the radio frequency plasma enhanced chemical vapor deposition method (RF-PECVD) with various si-lane concentrations. The influence of silane concentration o... A series of hydrogenated silicon thin films were prepared by the radio frequency plasma enhanced chemical vapor deposition method (RF-PECVD) with various si-lane concentrations. The influence of silane concentration on structural and elec-trical characteristics of these films was investigated to study the phase transition region from amorphous to microcrystalline phase. At the same time,optical emis-sion spectra (OES) from the plasma during the deposition process were monitored to get information about the plasma properties,Raman spectra were measured to study the structural characteristics of the deposited films. The combinatorial analysis of OES and Raman spectra results demonstrated that the OES can be used as a fast method to diagnose phase transition from amorphous to microcrystalline silicon. At last the physical mechanism,why both OES and Raman can be used to diagnose the phase transition,was analyzed theoretically. 展开更多
关键词 AMORPHOUS silicon MICROCRYSTALLINE silicon PHASE transition optical emission spectroscopy A series of hydrogenated silicon thin films were prepared by the radio frequency plasma enhanced chemical vapor deposition method (RF-PECVD) with various silane concentrations. The influence of silane concentration on structural and electrical characteristics of these films was investigated to study the PHASE TRANSITION region from AMORPHOUS to MICROCRYSTALLINE phase. At the same time optical emission spectra (OES) from the plasma during the deposition process were monitored to get information about the plasma properties Raman spectra were measured to study the structural characteristics of the deposited films. The combinatorial analysis of OES and Raman spectra results demonstrated that the OES can be used as a fast method to DIAGNOSE PHASE TRANSITION from AMORPHOUS to MICROCRYSTALLINE silicon. At last the physical mechanism why both OES and Raman can be used to DIAGNOSE the PHASE transition was analyzed theoretically.
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