Monitoring Zenithal Total Delays over the three different climatic zones from IGS GPS final products:A comparison between the use of the VMF1 and GMF mapping functions

The International GNSS Service(IGS) final products(ephemeris and clocks-correction) have made the GNSS an indispensable low-cost tool for scientific research, for example sub-daily atmospheric water vapor monitoring. In this study, we investigate if there is a systematic difference coming from the choice between the Vienna Mapping Function 1(VMF1) and the Global Mapping Function(GMF) for the modeling of Zenith Total Delay(ZTD) estimates, as well as the Integrated Precipitable Water Vapor(IPWV) estimates that are deduced from them. As ZTD estimates cannot be fully separated from coordinate estimates, we also investigated the coordinate repeatability between subsequent measurements.For this purpose, we monitored twelve GNSS stations on a global scale, for each of the three climatic zones(polar, mid-latitudes and tropical), with four stations on each zone. We used an automated processing based on the Bernese GNSS Software Version 5.2 by applying the Precise Point Positioning(PPP)approach, L3 Ionosphere-free linear combination, 7 cutoff elevation angle and 2 h sampling. We noticed an excellent agreement with the ZTD estimates and coordinate repeatability for all the stations w.r.t to CODE(the Center for Orbit Determination in Europe) and USNO(US Naval Observatory) products, except for the Antarctic station(Davis) which shows systematic biases for the GMF related results. As a final step, we investigated the effect of using two mapping functions(VMF1 and GMF) to estimate the IPWV,w.r.t the IPWV estimates provided by the Integrated Global Radiosonde Archive(IGRA). The GPS-derived IPWV estimates are very close to the radiosonde-derived IPWV estimates, except for one station in the tropics(Tahiti).

Readmission rate and early complications in patients undergoing total knee arthroplasty:A retrospective study

BACKGROUND Total knee arthroplasty(TKA)can improve pain,quality of life,and functional outcomes.Although uncommon,postoperative complications are extremely consequential and thus must be carefully tracked and communicated to patients to assist their decision-making before surgery.Identification of the risk factors for complications and readmissions after TKA,taking into account common causes,temporal trends,and risk variables that can be changed or left unmodified,will benefit this process.AIM To assess readmission rates,early complications and their causes after TKA at 30 days and 90 days post-surgery.METHODS This was a prospective and retrospective study of 633 patients who underwent TKA at our hospital between January 1,2017,and February 28,2022.Of the 633 patients,28 were not contactable,leaving 609 who met the inclusion criteria.Both inpatient and outpatient hospital records were retrieved,and observations were noted in the data collection forms.RESULTS Following TKA,the 30-day and 90-day readmission rates were determined to be 1.1%(n=7)and 1.8%(n=11),respectively.The unplanned visit rate at 30 days following TKA was 2.6%(n=16)and at 90 days was 4.6%(n=28).At 90 days,the unplanned readmission rate was 1.4%(n=9).Reasons for readmissions included medical(27.2%,n=3)and surgical(72.7%,n=8).Unplanned readmissions and visits within 90 days of follow-up did not substantially differ by age group(P=0.922),body mass index(BMI)(P=0.633),unilateral vs bilateral TKA(P=0.696),or patient comorbidity status(30-day P=0.171 and 90-day P=0.813).Reoperation rates after TKA were 0.66%(n=4)at 30 days and 1.15%(n=8)at 90 days.The average length of stay was 6.53 days.CONCLUSION In this study,there was a low readmission rate following TKA.There was no significant correlation between readmission rate and patient factors such as age,BMI,and co-morbidity status.

Reorganization characteristics of speech cortex during speech restoration following total laryngectomy A functional magnetic resonance imaging follow-up

During speech restoration following laryngectomy, language-related cortical areas develop connections with new primary motor neurons. The present study followed up 18 patients after total resection of laryngeal carcinoma. According to an evaluation of pronunciation, patients were assigned to three groups： poor, moderate and good pronunciation. Functional magnetic resonance imaging revealed significant increases in the number of activated voxels and the intensity of activation changes in the left middle frontal gyrus, left precentral gyrus, left postcentral gyrus, left supplementary motor area, left anterior cingulate gyrus and right fusiform gyrus between the moderate pronunciation group compared with the poor and good pronunciation groups. We propose that these brain regions play an important role in the progress of speech restoration, and improvements in pronunciation learning for patients following laryngectomy. However, during the later period of speech restoration, the number of activated voxels and intensity changes in these regions decreased to the level of healthy controls, indicating that the learning and instruction effects weakened once patients had mastered pronunciation techniques

Dynamic analysis of spatial convergence of green total factor productivity in China's primary provinces along its Belt and Road Initiative

This paper focuses on China's primary provinces along its Belt and Road Initiative,measures and analyses the provincial green total factor productivity (GTFP) development by GML index based on SBM directional distance function,discusses the temporal evolution characteristics of spatial convergence of the provincial GTFP under multiple spatial weight matrices,and estimates the net effect of China's Belt and Road Initiative on the development gap of provincial GTFP by regression discontinuity.The research shows that the provincial GTFP is generally good while the internal gap is relatively large.There is spatial absolute βconvergence and condition βconvergence in provincial GTFP,and the convergence speed has been signifcantly accelerated since the construction of China's Belt and Road Initiative.The current low economy level and infrastructure allocation efficiency of primary provinces restrict the GTFP development,while government expenditure has promoted the GTFP development,trade between provinces and countries along China's Belt and Road Initiative is negative to GTFP.China's Belt and Road Initiative has significantly narrowed the gap of provincial GTFP development with the net effect of-0.016.

温度和热驯化对胡氏大生熊虫运动行为的影响

The beneficial acclimation hypothesis (BAH) predicts that animals acclimated to a particular temperature have enhanced performance or fitness at that temperature in comparison with animals acclimated to other temperatures. The BAH has been tested by a variety of empirical examinations, and was rejected by some of them. In order to provide new evidences for the BAH, the effects of acute and acclimation temperature (AT) on locomotor performance of Macrobiotus hufelandi (Tardigrada: Macrobiotidae) were investigated. The tardigrades were collected from Nanwutai, Qinling Mountains which traverse from west to east in central China. The subjects were acclimated to either 2℃ or 22℃ for 2 weeks. The animal was transferred onto a frosted slide and allowed to walk freely at the performance temperature (PT) 2℃ or 22℃. Only one individual was tested per test bout, which lasted from three to five minutes. To avoid occurrence of thermal acclimation effect, the standard adaptation time was limited to 1.5 min. Each subject was tested for once at the same PT, and was tested only at one PT. A total of 25 individuals were tested and measured at the same PT. The locomotor performance of the animals was recorded with a digital video camera mounted on a microscope at 4×10 amplification and replayed on a PC. Every subject was identified. Walking speed (WS) and percentage of time moving (PTM) at both PTs (2℃ or 22℃) were selected as the rate parameters of locomotor performance. The two-way repeated measures ANOVA with a significance level of α= 0.05 and Duncan multiple range test were used to analyze the data. WS of the animals acclimated to and tested at the same temperatures was significantly faster than that for animals acclimated to and tested at the different temperatures, similarly, PTM of the animals acclimated to 22℃ and tested at 22℃ was significantly greater than PTM of animals acclimated to 22℃ and tested at 2℃, which indicated that the animals acclimated to a particular temperature have enhanced locomotor performance in that temperature relative to the animals acclimated to that temperature in other thermal environment. WS of the animals acclimated to 22℃ and tested at 22℃ was significantly faster than WS of animals acclimated to 2℃ and tested at 22℃, PTM of the animals acclimated to 22℃ and tested at 22℃ was significantly greater than PTM of animals acclimated to 2℃ and tested at 22℃. These results supported the BAH. It could be concluded that the PT and thermal acclimation as well as the interaction between the PT and AT significantly influence the locomotor performance of M.hufelandi, and that, despite the existence of a few results of this study that don’t support the BAH, some results of this study support for this hypothesis, and that the animals acclimated to a particular temperature have enhanced locomotor performance in that temperature relative to the animals acclimated to that temperature in other thermal environment, implying that any performance temperature that deviates from the acclimation temperature could cause the reduction of the walking speed which is closely related to the fitness of the M.hufelandi.

Retrospective review of total neoadjuvant therapy

BACKGROUND Neoadjuvant chemoradiotherapy(nCRT)followed by resection and postoperative multi-agent chemotherapy(maChT)is the standard of care for locally advanced rectal cancer.Using this approach,maChT administration can be delayed for several months,leading to concern for distant metastases.To counteract this,a novel treatment approach known as total neoadjuvant therapy(TNT)has gained popularity,in which patients receive both maChT and nCRT prior to resection.We utilized the National Cancer Database to examine temporal trends in TNT usage,and any potential effect on survival.AIM To study the temporal trends in the usage of TNT and evaluate its efficacy compared to neoadjuvant chemoradiation.METHODS We queried the National Cancer Database for patients with locally advanced rectal cancer,Stage II-III,from 2004-2015 treated with nCRT or TNT.TNT was defined as maChT initiated≥90 d prior to nCRT initiation.Overall survival was calculated from the date of diagnosis to the date of last contact or death using Kaplan-Meier curves to present the cumulative probability of survival,with logrank statistics to assess significance.Multivariable cox regression was used to identify predictors of survival and propensity score analysis accounted for bias.RESULTS We identified 9066 eligible patients,with 8812 and 254 patients receiving neoadjuvant chemoradiation followed by maChT and TNT,respectively.Nodal involvement,stage III disease,and treatment in recent years were predictive of TNT use.There was greater use of TNT with more advanced stage,specifically>1 node involved(odds ratio[OR]=2.88,95%confidence interval[CI]:2.11-3.93,P<0.01)and stage III disease(OR=2.88,95%CI:2.11-3.93,P<0.01).From 2010 to 2012 the use of TNT increased(OR=2.41,95%CI:1.27-4.56,P<0.01)with a greater increase from 2013 to 2015(OR=6.62,95%CI:3.57-12.25,P<0.01).Both the TNT and neoadjuvant chemoradiation arms had a similar 5-year survival at 76%and 78%respectively.Multivariable analysis with propensity score demonstrated that increased age,high comorbidity score,higher grade,African American race,and female gender had worse overall survival.CONCLUSION Our data demonstrates a rising trend in TNT use,particularly in patients with worse disease.Patients treated with TNT and nCRT had similar survival.Randomized trials evaluating TNT are underway.

Research on Total Electric Field for DC Lines Converted from Double-Circuit AC Lines

With rapid growth of power demand, transmission capacity is also in urgent need of upgrading. In some cases, converting existing AC transmission lines to DC lines can Improve the transmission capacity and reduce the construction investment. In this paper, the upstream finite element method was expanded to calculate the total electric field of same tower multi-circuit DC lines converted from double-circuit AC lines, and the validity of the algorithm was confirmed by experiments. Taking a DC line converted from a typical same tower 500 kV double-circuit AC transmission line as an example, the surface electric field and the ground total electric field in different pole conductor arrangement schemes were calculated and analyzed, and the critical height of pole conductors for DC lines in residential and non-residential area were determined. Then, the corridor width of DC and AC lines at critical height in residential and non-residential areas before and after AC-DC line transformation were compared. The results indicate that for DC lines converted from common 500 kV double-circuit AC lines, the ground total electric field can meet the requirements of corresponding standard with appropriate pole conductor arrangement schemes.

Manifestations of the earthquake preparations in the ionosphere total electron content variations

Recent ionospheric observations report anomalous total electron content (TEC) deviations prior strong earthquakes. We discuss common fetures of the pre-earthquake TEC disturbances on the basis of statistics covering 50 strong seismic events during 2005-2006. The F2-layer ionospheric plasma drift under action of the electric fields of seismic origin is proposed as the main reason of producing TEC anomalies. The origin of such electric fields is discussed in terms of the lithosphere-atmosphere-ionosphere coupling system. This theory is supported by numerical simulations using global Upper Atmosphere Model (UAM). UAM calculations show that the vertical electric current with the density of about 20 - 40 nA/m2 flowing between the Earth and ionosphere over an area of about 200 by 2000 km is required to produce the TEC disturbances with the amplitude of about 30% - 50% relatively to the non-disturbed conditions. Ionosphere responses on the variations of the latitudinal position, direction and configuration of the vertical electric currents have been investigated. We show that not only the vertical component of the ionospheric plasma drift but also horizontal components play an important role in producing pre-earthquake TEC disturbances.

Comparison of Mathematical Equations Applicable to Tolerance of Total Body Irradiation in Humans and Decay of Isotopes, Uranium and Thorium: Differences and Similarity

A clear and exact quantitative relationship between dose of total body irradiation and mortality in humans is still not known because of lack of human data that would enable us to determine LD50 for humans in total body irradiation. Analysis of human data has been primarily from radiation accidents, radiotherapy and the atomic bomb victims. The author published the general mathematical equations of LD50 constructed on the basis of data presented by Cerveny, MacVittie and Young, employing the probacent formula model. In this study, the author compared the equations of tolerance of total body irradiation and decay of isotopes, uranium and thorium. Differences and similarity in these equations of the two groups are presented. The significance of similarity is specially described.

Mid-term outcomes of a kinematically designed cruciate retaining total knee arthroplasty

BACKGROUND Advances in implant material and design have allowed for improvements in total knee arthroplasty(TKA)outcomes.A cruciate retaining(CR)TKA provides the least constraint of TKA designs by preserving the native posterior cruciate ligament.Limited research exists that has examined clinical outcomes or patient reported outcome measures(PROMs)of a large cohort of patients undergoing a CR TKA utilizing a kinematically designed implant.It was hypothesized that the studied CR Knee System would demonstrate favorable outcomes and a clinically significant improvement in pain and functional scores.AIM To assess both short-term and mid-term clinical outcomes and PROMs of a novel CR TKA design.METHODS A retrospective,multi-surgeon study identified 255 knees undergoing a TKA utilizing a kinematically designed CR Knee System(JOURNEY™II CR;Smith and Nephew,Inc.,Memphis,TN)at an urban,academic medical institution between March 2015 and July 2021 with a minimum of two-years of clinical follow-up with an orthopedic surgeon.Patient demographics,surgical information,clinical outcomes,and PROMs data were collected via query of electronic medical records.The PROMs collected in the present study included the Knee Injury and Osteoarthritis Outcome Score for Joint Replacement(KOOS JR)and Patient-Reported Outcomes Measurement Information System(PROMIS■)scores.The significance of improvements in mean PROM scores from preoperative scores to scores collected at six months and two-years postoperatively was analyzed using Independent Samples t-tests.RESULTS Of the 255 patients,65.5%were female,43.8%were White,and patients had an average age of 60.6 years.Primary osteoarthritis(96.9%)was the most common primary diagnosis.The mean surgical time was 105.3 minutes and mean length of stay was 2.1 d with most patients discharged home(92.5%).There were 18 emergency department(ED)visits within 90 d of surgery resulting in a 90 d ED visit rate of 7.1%,including a 2.4%orthopedic-related ED visit rate and a 4.7%non-orthopedic-related ED visit rate.There were three(1.2%)hospital readmissions within 90 d postoperatively.With a mean time to latest follow-up of 3.3 years,four patients(1.6%)required revision,two for arthrofibrosis,one for aseptic femoral loosening,and one for peri-prosthetic joint infection.There were significant improvements in KOOS JR,PROMIS Pain Intensity,PROMIS Pain Interference,PROMIS Mobility,and PROMIS Physical Health from preoperative scores to six month and two-year postoperative scores.CONCLUSION The evaluated implant is an effective,novel design offering excellent outcomes and low complication rates.At a mean follow up of 3.3 years,four patients required revisions,three aseptic and one septic,resulting in an overall implant survival rate of 98.4%and an aseptic survival rate of 98.8%.The results of our study demonstrate the utility of this kinematically designed implant in the setting of primary TKA.

Perioperative blood management strategies for patients undergoing total knee replacement:Where do we stand now?

Total knee replacement(TKR) is one of the most common surgeries over the last decade. Patients undergoing TKR are at high risk for postoperative anemia and furthermore for allogeneic blood transfusions(ABT). Complications associated with ABT including chills, rigor, fever, dyspnea, light-headedness should be early recognized in order to lead to a better prognosis. Therefore, perioperative blood management program should be adopted with main aim to reduce the risk of blood transfusion while maximizing hemoglobin simultaneously. Many blood conservation strategies have been attempted including preoperative autologous blood donation, acute normovolemic haemodilution, autologous blood transfusion, intraoperative cell saver, drain clamping, pneumatic tourniquet application, and the use of tranexamic acid. For practical and clinical reasons we will try to classify these strategies in three main stages/pillars: Pre-operative optimization, intra-operative and post-operative protocols. The aim of this work is review the strategies currently in use and reports our experience regarding the perioperative blood management strategies in TKR.

Algorithms and statistical analysis for linear structured weighted total least squares problem

Weighted total least squares(WTLS)have been regarded as the standard tool for the errors-in-variables(EIV)model in which all the elements in the observation vector and the coefficient matrix are contaminated with random errors.However,in many geodetic applications,some elements are error-free and some random observations appear repeatedly in different positions in the augmented coefficient matrix.It is called the linear structured EIV(LSEIV)model.Two kinds of methods are proposed for the LSEIV model from functional and stochastic modifications.On the one hand,the functional part of the LSEIV model is modified into the errors-in-observations(EIO)model.On the other hand,the stochastic model is modified by applying the Moore-Penrose inverse of the cofactor matrix.The algorithms are derived through the Lagrange multipliers method and linear approximation.The estimation principles and iterative formula of the parameters are proven to be consistent.The first-order approximate variance-covariance matrix(VCM)of the parameters is also derived.A numerical example is given to compare the performances of our proposed three algorithms with the STLS approach.Afterwards,the least squares(LS),total least squares(TLS)and linear structured weighted total least squares(LSWTLS)solutions are compared and the accuracy evaluation formula is proven to be feasible and effective.Finally,the LSWTLS is applied to the field of deformation analysis,which yields a better result than the traditional LS and TLS estimations.

Silymarin in non alcoholic fatty liver disease

AIM: This study was undertaken to evaluate the hepatic effects of silybum marianum on non alcoholic fatty liver disease (NAFLD). METHODS: In 72 patients affected by NAFLD, main metabolic, hepatic and anti-inflammatory parameters were assayed after 3 mo of a restricted diet and before silymarin treatment (twice a day orally). The brightness of liver echography texture (hepatorenal ratio brightness) was also defined at same time. These evaluations were repeated after 6 mo of treatment. RESULTS: Serum levels of some metabolic and anti-inflammatory data nonsignificantly lowered after 6 mo of silymarin. On the contrary, Steato test, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and gamma-glutamyl transpeptidase were significantly (P < 0.001) reduced. Instead, the AST/ALT ratio unchanged. Finally, the hepatorenal brightness ratio, as an index of hepatic steatosis, significantly (P < 0.05) dropped. CONCLUSION: The obtained results indicate that silymarin appears to be effective to reduce the biochemical, inflammatory and ultrasonic indices of hepatic steatosis. Some parameters indicative of early stage of atherosclerosis were also lowered.

Common controversies in total knee replacement surgery: Current evidence

Total knee replacement(TKR) is a widely used operation that has radically improved the quality of life of millions of people during the last few decades. However, some technical details, concerning the surgical procedure and the rehabilitation following total knee arthroplasty, are still a matter of a strong debate. In this review of the literature, we have included the best evidence available of the last decade, in an effort to shed light on some of the most controversial subjects related to TKR surgery. Posterior-stabilized or cruciate-retaining prosthesis? To use a tourniquet during operation or not? Do patients need continuous passive motion for their post-surgery rehabilitation? To resurface patella or not? These are some of the most controversial topics that until now have been persistent dilemmas for the orthopedic surgeon. Results of this systematic review of the literature are highly controversial. These conflicting results are an indication that larger and more well conducted high quality trials are needed in order to gain more secure answers. At the same time, it is becoming apparent that a meticulous operative technique, respecting the soft tissue envelope and knowing the principles of alignment and soft tissue balancing, aresome of the parameters that might contribute more to achieving the optimal results for the patients.

Effect of weight-adjusted antimicrobial antibiotic prophylaxis on postoperative dosage and surgical site infection incidence in total joint arthroplasty

Surgical site infections(SSI)following total joint arthroplasty pose a significant concern for both providers and patients across the globe.Currently,administration of antimicrobial antibiotic prophylaxis is used throughout the world to reduce the incidence of SSI.However,the correct dosage and frequency of administration remains debatable.In this editorial,we emphasized the determination of the effect of administration of weight-adjusted antimicrobial antibiotic prophylaxis regime on the incidence of SSI and postoperative dosage reduction compared to the conventionally used regime during total joint arthroplasty.The results demonstrated similar efficacy between both regimes with respect to the incidence of SSI.In addition,weight-adjustment led to reduced postoperative dosage and has the potential to reduce chances of achieving lower therapeutic concentration,drug resistance,drug toxicity,and costs.

Which approach of total hip arthroplasty is the best efficacy and least complication?

BACKGROUND Total hip arthroplasty is as an effective intervention to relieve pain and improve hip function.Approaches of the hip have been exhaustively explored about pros and cons.The efficacy and the complications of hip approaches remains inconclusive.This study conducted an umbrella review to systematically appraise previous meta-analysis(MAs)including conventional posterior approach(PA),and minimally invasive surgeries as the lateral approach(LA),direct anterior approach(DAA),2-incisions method,mini-lateral approach and the newest technique direct superior approach(DSA)or supercapsular percutaneouslyassisted total hip(SuperPath).AIM To compare the efficacy and complications of hip approaches that have been published in all MAs and randomized controlled trials(RCTs).METHODS MAs were identified from MEDLINE and Scopus from inception until 2023.RCTs were then updated from the latest MA to September 2023.This study included studies which compared hip approaches and reported at least one outcome such as Harris Hip Score(HHS),dislocation,intra-operative fracture,wound compliData were independently selected,extracted and assessed by two reviewers.Network MA and cluster rank and surface under the cumulative ranking curve(SUCRA)were estimated for treatment efficacy and safety.RESULTS Finally,twenty-eight MAs(40 RCTs),and 13 RCTs were retrieved.In total 47 RCTs were included for reanalysis.The results of corrected covered area showed high degree(13.80%).Among 47 RCTs,most of the studies were low risk of bias in part of random process and outcome reporting,while other domains were medium to high risk of bias.DAA significantly provided higher HHS at three months than PA[pooled unstandardized mean difference(USMD):3.49,95%confidence interval(CI):0.98,6.00 with SUCRA:85.9],followed by DSA/SuperPath(USMD:1.57,95%CI:-1.55,4.69 with SUCRA:57.6).All approaches had indifferent dislocation and intraoperative fracture rates.SUCRA comparing early functional outcome and composite complications(dislocation,intra-operative fracture,wound complication,and nerve injury)found DAA was the best approach followed by DSA/SuperPath.CONCLUSION DSA/SuperPath had better earlier functional outcome than PA,but still could not overcome the result of DAA.This technique might be the other preferred option with acceptable complications.

贺兰山保护区冬季岩羊集群特征的初步分析

Group size and composition of blue sheep(Pseudois nayaur)were studied in the Helan Mountains, Ningxia Autonomous Region from November to December 2003.We scanned mountain slopes with binoculars and observed with 20-60× spotting-scope. A total of 310 herds of blue sheep and 1 336 individuals were observed during the study period. Blue sheep were frequently seen in small herds of 2 to 8 individuals, which represent 94.8% of total herds observed. Herds consisting of 9 individuals or more represented 5.2%. The largest herd we observed numbered 51 individuals. Mean group size was 4.2 individuals. Blue sheep herds can be divided into three types: male herds (composed solely of males), female herds (consisting of females with or without juveniles of both sexes), and mixed herds (including adult males, females, and subadults).Among the 310 herds, female herds were counted 150 times(48.4%), mixed herds 154 times(49.7%), and male herds 6 times(1.9%). Of 1 336 blue sheep classified by sex and age, adults, subadults and juveniles composed 64.1%,20.8%, and 15.1% respectively. The female:male ratio of adults was 1∶0.73. The ratio of adult females to juveniles was 1∶0.56, which is higher than the ratio recorded in spring (1∶0.43) or summer (1∶0.44).The results showed that the Helan Mountains State Nature Reserve has succeed in protecting blue sheep.

底栖鱼类对水田上覆水中磷素动态的扰动效应(摘要)(英文)

[目的]研究底栖鱼类泥鳅对水田上覆水中磷素动态的扰动效应,探讨生物扰动机制。[方法]基于模拟试验,使用离子色谱法和分光光度法,对比分析上覆水中磷素含量在有/无泥鳅活动时的差异。[结果]扰动组的TP、DTP和PP浓度在试验开始阶段与对照组无显著差异,在试验中、后期显著高于对照(P<0.05)。扰动组的PP/TP高于对照组,扰动组中TP浓度的增加主要是由于PP的增加。扰动组的DIP/DTP在试验中、后期显著高于对照(P<0.05)。[结论]底栖鱼类对水田上覆水中的磷素产生了扰动作用,增加了水稻生长可利用的磷素养分。

A Qualitative Study on Experiences of Patients with Esophageal Speech Training after Total Laryngectomy

Background: Patients who had total laryngectomy not only have a pressure from the possible diagnosis of laryngeal cancer, but also suffer from unspeakable misery. To relieve the suffering, some patients choose esophageal speech training. However, most of the current researches focus solely on the results of the training with the negligence of the patients’ mental health and their life experience during the training. A qualitative research is highly sensitive to patients’ subjective feelings, and thus able to capture their subtle emotional changes. Objective: To explore deeply patients’ real experiences of esophageal speech training after total laryngectomy and reveal the public their training experience of the unique and special group. Methods: In May 2018, researchers conducted a two-month field observation on and in-depth interviews with 15 patients who were on esophageal speech training after total laryngectomy in the esophageal speech training room of the Eye and ENT Hospital of Fudan University. The research applied phenomenological research method and Colaizzi Data Analysis. Results: The data analysis indicated four main themes: changes of mindset;showing positive attitudes and behaviors in training;shift in social relations;and arduous training process. Conclusion: The study has the finding that patients on esophageal speech training had negative emotions in the early stage of the training and dissatisfaction with its teaching. The repercussion of the surgery brought them changes of social relations, social bias and prejudice ensued. It is, therefore, urgent and crucial to give the speech trainees psychological counseling in the early stage to improve their qualities of life, to mobilize social support to incentivize their training, to optimize esophageal speech training teaching, and to regulate the management of the esophageal speech training environment.

Numerical Analyses of Idealized Total Cavopulmonary Connection Physiologies with Single and Bilateral Superior Vena Cava Assisted by an Axial Blood Pump

Our study evaluated the hemodynamic performance of an axial flow blood pump surgically implanted in idealized total cavopulmonary connection(TCPC)models.This blood pump was designed to augment pressure from the inferior vena cava(IVC)to the pulmonary circulation.Two Fontan procedures with single and bilateral superior vena cava(SVC)were compared to fit the mechanical supported TCPC physiologies.Computational fluid dynamics(CFD)analyses of two Pump-TCPC models were performed in the analyses.Pressure-flow characteristics,energy efficiency,fluid streamlines,hemolysis and thrombosis analyses were implemented.Numerical simulations indicate that the pump produces pressure generations of 1 mm to 24 mm Hg for rotational speeds ranging from 2000 RPM to 5000 RPM and flow rates of 2 LPM to 4 LPM.Two surgical models incorporated with the pump were found to be insignificant in pressure augmentation and energy boost.The risk assessment of blood trauma and thrombosis generation was evaluated representatively through blood damage index(BDI),particle resident time(PRT)and relative resistant time(RRT).The hemolysis and thrombosis analyses declare the advantage of the pump supported bilateral SVC surgical scheme in balancing flow distribution and reducing the risk of endothelial cell destruction and trauma generation.