Let p be a prime. For any finite p-group G, the deep transfers T H,G ' : H / H ' → G ' / G " from the maximal subgroups H of index (G:H) = p in G to the derived subgroup G ' are introduced as an ...Let p be a prime. For any finite p-group G, the deep transfers T H,G ' : H / H ' → G ' / G " from the maximal subgroups H of index (G:H) = p in G to the derived subgroup G ' are introduced as an innovative tool for identifying G uniquely by means of the family of kernels ùd(G) =(ker(T H,G ')) (G: H) = p. For all finite 3-groups G of coclass cc(G) = 1, the family ùd(G) is determined explicitly. The results are applied to the Galois groups G =Gal(F3 (∞)/ F) of the Hilbert 3-class towers of all real quadratic fields F = Q(√d) with fundamental discriminants d > 1, 3-class group Cl3(F) □ C3 × C3, and total 3-principalization in each of their four unramified cyclic cubic extensions E/F. A systematic statistical evaluation is given for the complete range 1 d 7, and a few exceptional cases are pointed out for 1 d 8.展开更多
In this paper the Expendable Pattern Casting with dry sand Vacuum(EPC-V) process is used to manufacture iron matrix composites with tungsten carbide particle.Microstructures of the composites layers were analyzed.The ...In this paper the Expendable Pattern Casting with dry sand Vacuum(EPC-V) process is used to manufacture iron matrix composites with tungsten carbide particle.Microstructures of the composites layers were analyzed.The abrasive wear resistance of the composites layers were tested and compared with that of high chromium cast iron.The results show that the iron matrix composites with tungsten carbide particle have high hardness.The abrasive wear resistance of composites with tungsten carbide particle is higher than that of high chromium cast iron.The properties of the matrix materials have been improved remarkably.展开更多
The most significant changes of landscape in a certain period are landscape area changes and spatial changes of landscape patches.Based on transfer matrix and total amount change of landscape area,landscape space tran...The most significant changes of landscape in a certain period are landscape area changes and spatial changes of landscape patches.Based on transfer matrix and total amount change of landscape area,landscape space transfer index and landscape area change index were established,and then applied to analyze plain oasis and desert in Yutian County,Xinjiang Uyghur Nationality Autonomous Region,the results showed that landscape space transfer in this region was drastic,but total landscape area changed only slightly,thus space transfer index was much higher than area change index,which indicated that landscapes in arid area were given with particular spatial undulant features and sensitivity,while man-made landscapes(artificial oasis) are stable and expanding to some extent.With landscape space transfer index as the comprehensive indicator,space transfer intensity of landscape within a certain period can be demonstrated,which is favorable for the comparison of landscape change intensity among different types and within different periods,in addition,some macroscopic change features of landscapes can also be reflected by comprehensively analyzing landscape space transfer index and landscape area change index.展开更多
IgG Check calf test has been used in this study to identify if a failure of passive transfer occurs in neonatal calves by measuring the level of IgG in blood. An adequate level of IgG measured in all calves at 48 hour...IgG Check calf test has been used in this study to identify if a failure of passive transfer occurs in neonatal calves by measuring the level of IgG in blood. An adequate level of IgG measured in all calves at 48 hours, 7 days and 14 days after birth showed level of IgG 1000 mg/dl. This level indicated that they have good passive transfer of immunity. Also, in this study colostrum quality fed to calves was detected using Brix Refractometer. The colostrum is of high quality as it contains 50 mg/ml of IgG. This Brix refractometer can be used on the farm level to estimate colostrum IgG content and monitoring colostrum feeding practices. Colostrum with high quality IgG could provide calves with enough IgG to attain successful passive transfer of immunity. Brix and Obione refractometers provide simple, rapid method for estimating IgG concentration on calf serum, thus considered to be the most common method for determining passive transfer failure.展开更多
We theoretically investigate the excited state intramolecular proton transfer(ESIPT) behavior of the novel fluorophore bis-imine derivative molecule HNP which was designed based on the intersection of 1-(hydrazonometh...We theoretically investigate the excited state intramolecular proton transfer(ESIPT) behavior of the novel fluorophore bis-imine derivative molecule HNP which was designed based on the intersection of 1-(hydrazonomethyl)-naphthalene-2-ol and 1-pyrenecarboxaldehyde. Especially, the density functional theory(DFT) and time-dependent density functional theory(TDDFT) methods for HNP monomer are introduced. Moreover, the "our own n-layered integrated molecular orbital and molecular mechanics"(ONIOM) method(TDDFT:universal force field(UFF)) is used to reveal the aggregation-induced emission(AIE) effect on the ESIPT process for HNP in crystal. Our results confirm that the ESIPT process happens upon the photoexcitation for the HNP monomer and HNP in crystal, which is distinctly monitored by the optimized geometric structures and the potential energy curves. In addition, the results of potential energy curves reveal that the ESIPT process in HNP will be promoted by the AIE effect. Furthermore, the highest occupied molecular orbital(HOMO) and lowest unoccupied molecular orbital(LUMO) for the HNP monomer and HNP in crystal have been calculated. The calculation demonstrates that the electron density decrease of proton donor caused by excitation promotes the ESIPT process. In addition, we find that the variation of atomic dipole moment corrected Hirshfeld population(ADCH) charge for proton acceptor induced by the AIE effect facilitates the ESIPT process. The results will be expected to deepen the understanding of ESIPT dynamics for luminophore under the AIE effect and provide insight into future design of high-efficient AIE compounds.展开更多
This present paper deals with a mathematical description of linear axial and torsional vibrations. The normal and tangential stress tensor components produced by axial-torsional deformations and vibrations in the prop...This present paper deals with a mathematical description of linear axial and torsional vibrations. The normal and tangential stress tensor components produced by axial-torsional deformations and vibrations in the propeller and intermediate shafts, under the influence of propeller-induced static and variable hydrodynamic excitations are also studied. The transfer matrix method related to the constant coefficients of differential equation solutions is used. The advantage of the latter as compared with a well-known method of transfer matrix associated with state vector is the possibility of reducing the number of multiplied matrices when adjacent shaft segments have the same material properties and diameters. The results show that there is no risk of buckling and confirm that the strength of the shaft line depends on the value of the static tangential stresses which is the most important component of the stress tensor.展开更多
Objectives: To describe the versatility of acellular fetal bovine dermal matrix as an alternative to human cadaveric allograft for head and neck reconstructive procedures in children. Study Design: Case series with ch...Objectives: To describe the versatility of acellular fetal bovine dermal matrix as an alternative to human cadaveric allograft for head and neck reconstructive procedures in children. Study Design: Case series with chart review. Methods: A database of pediatric operative procedures was queried for the use of acellular fetal bovine dermal matrix over a 16-month period. Indications for reconstruction were assessed and initial parental and surgeon satisfaction with the product were noted. Results: During the time period of 3/2012 and 7/2013 a total of 8 reconstructive procedures were performed on pediatric patients using acellular fetal bovine dermal matrix. Indications for use varied and included open and transnasal endoscopic repair of encephaloceles and soft tissue reconstructions including lateral pharyngeal wall repair, cleft palate repair, and facial recontouring operations. Acellular fetal bovine dermal matrix had a subjectively increased ease of use as compared to the surgeon’s prior experience with human cadaveric acellular dermis. Every parent vocalized a greater comfort level with the use of a bovine product over the alternative of human cadaveric tissue. The cost of acellular fetal bovine dermal matrix is slightly lower than the cost of human cadaveric acellular dermis. Conclusions: Acellular fetal bovine dermal matrix appears to be an acceptable alternative to human cadaveric acellular dermis for various forms of head and neck soft tissue reconstruction in children. Further prospective studies are warranted to assess for any differences in the long-term efficacy of this product as compared to other forms of allograft reconstruction.展开更多
In this paper the results of dynamic NMR studies on ethylmethylamino-tertiary-butyl-phenylborane (EMABPB) with or without light are reported. The NMR data were recorded on a Bruker 400 MHz NMR equipped with our custom...In this paper the results of dynamic NMR studies on ethylmethylamino-tertiary-butyl-phenylborane (EMABPB) with or without light are reported. The NMR data were recorded on a Bruker 400 MHz NMR equipped with our custom-made optical probe and with our custom-made 450 watts (W) monochromatic light sources. The molecular photochemistry including twisted intramolecular charge-transfer-excited-state (TICT) of the EMABPB in several solvents has been investigated. These results indicate that the aminoborane demonstrates multiple configurations in CD3Cl and CD2Cl2 resulting in the shifts of the signals of the alkyl groups on the nitrogen and boron. This indicates that there are some time-dependent changes at constant temperature over the irradiation interval. At ﹣60°C and the presence of light (λ = 265 nm), we observed a large change in the populations of the two sites, and this by itself indicates a modification in the rotation around the boron nitrogen bond in the excited state. By considering the existence of the TICT state, many important energy technologies may be developed with higher efficiency by controlling the back-electron transfer processes.展开更多
Cell-cell and cell-matrix signaling and communication between adhesion sites involve mechanisms which are required for cellular functions during normal development and homeostasis; however these cellular functions and...Cell-cell and cell-matrix signaling and communication between adhesion sites involve mechanisms which are required for cellular functions during normal development and homeostasis; however these cellular functions and mechanisms are often deregulated in cancer. Aberrant signaling at cell-cell and cell-matrix adhesion sites often involves downstream mediators including Rho GTPases and tyrosine kinases. This review discusses these molecules as putative mediators of cellular crosstalk between cell-cell and cell-matrix adhesion sites, in addition to their attractiveness as therapeutic targets in cancer. Interestingly, inter-junctional crosstalk mechanisms are frequently typified by the way in which bacterial and viral pathogens opportunistically infect or intoxicate mammalian cells. This review therefore also discusses the concept of learning from pathogen-host interaction studies to better understand coordinated communication between cell-cell and cell-matrix adhesion sites, in addition to highlighting the potential therapeutic usefulness of exploiting pathogens or their products to tap into inter-junctional crosstalk. Taken together, we feel that increased knowledge around mechanisms of cell-cell and cell-matrix adhesion site crosstalk and consequently a greater understanding of their therapeutic targeting offers a unique opportunity to contribute to the emerging molecular revolution in cancer biology.展开更多
The present pagination reports both Brownian diffusion and thermophoresis aspects subject to magneto hydrodynamic Williamson fluid model.Assuming the flow is unsteady and blood is treated as Williamson fluid over a we...The present pagination reports both Brownian diffusion and thermophoresis aspects subject to magneto hydrodynamic Williamson fluid model.Assuming the flow is unsteady and blood is treated as Williamson fluid over a wedge with radiation.The governing equations are transformed into ordinary differential equations by using similarity variables.The analytical solutions of the transformed governing equations are obtained by using the RK 4th order method along with shooting technique solver.The effects of various physical parameters such as Hartmann number,local Weissenberg number,radiation parameter,unsteadiness parameter,Prandtl number,Lewis number,Brownian diffusion,thermophoresis,wedge angle parameter,moving wedge parameter,on velocity,temperature,concentration,skin friction,heat transfer rate and mass transfer rate have been discussed in detail.The velocity and temperature profile deprives for larger We and an opposite trend is observed for concentration.The radiation parameter is propositional to temperature and a counter behaviour is observed for Pr.展开更多
Vascular endothelial growth factor and its mimic peptide KLTWQELYQLKYKGI(QK)are widely used as the most potent angiogenic factors for the treatment of multiple ischemic diseases.However,conventional topical drug deliv...Vascular endothelial growth factor and its mimic peptide KLTWQELYQLKYKGI(QK)are widely used as the most potent angiogenic factors for the treatment of multiple ischemic diseases.However,conventional topical drug delivery often results in a burst release of the drug,leading to transient retention(inefficacy)and undesirable diffusion(toxicity)in vivo.Therefore,a drug delivery system that responds to changes in the microenvironment of tissue regeneration and controls vascular endothelial growth factor release is crucial to improve the treatment of ischemic stroke.Matrix metalloproteinase-2(MMP-2)is gradually upregulated after cerebral ischemia.Herein,vascular endothelial growth factor mimic peptide QK was self-assembled with MMP-2-cleaved peptide PLGLAG(TIMP)and customizable peptide amphiphilic(PA)molecules to construct nanofiber hydrogel PA-TIMP-QK.PA-TIMP-QK was found to control the delivery of QK by MMP-2 upregulation after cerebral ischemia/reperfusion and had a similar biological activity with vascular endothelial growth factor in vitro.The results indicated that PA-TIMP-QK promoted neuronal survival,restored local blood circulation,reduced blood-brain barrier permeability,and restored motor function.These findings suggest that the self-assembling nanofiber hydrogel PA-TIMP-QK may provide an intelligent drug delivery system that responds to the microenvironment and promotes regeneration and repair after cerebral ischemia/reperfusion injury.展开更多
The dynamic stiffness method and Transfer method is applied to study the vibration characteristics of the Euler-Bernoulli pipe conveying fluid in this paper. According to the dynamics equation of the pipe conveying fl...The dynamic stiffness method and Transfer method is applied to study the vibration characteristics of the Euler-Bernoulli pipe conveying fluid in this paper. According to the dynamics equation of the pipe conveying fluid, the element dynamic stiffness is established. The vibration characteristic of the single-span pipe is analyzed under two kinds of boundary conditions. The results compared with the literature, which has a good consistency. Based on this method, natural frequency and the critical speed of the two types of multi-span pipe are deserved. This paper shows that the dynamic stiffness method and transfer matrix is an effective method to deal with the vibration problem of pipe conveying fluid.展开更多
Neuronal growth, extension, branching, and formation of neural networks are markedly influenced by the extracellular matrix—a complex network composed of proteins and carbohydrates secreted by cells. In addition to p...Neuronal growth, extension, branching, and formation of neural networks are markedly influenced by the extracellular matrix—a complex network composed of proteins and carbohydrates secreted by cells. In addition to providing physical support for cells, the extracellular matrix also conveys critical mechanical stiffness cues. During the development of the nervous system, extracellular matrix stiffness plays a central role in guiding neuronal growth, particularly in the context of axonal extension, which is crucial for the formation of neural networks. In neural tissue engineering, manipulation of biomaterial stiffness is a promising strategy to provide a permissive environment for the repair and regeneration of injured nervous tissue. Recent research has fine-tuned synthetic biomaterials to fabricate scaffolds that closely replicate the stiffness profiles observed in the nervous system. In this review, we highlight the molecular mechanisms by which extracellular matrix stiffness regulates axonal growth and regeneration. We highlight the progress made in the development of stiffness-tunable biomaterials to emulate in vivo extracellular matrix environments, with an emphasis on their application in neural repair and regeneration, along with a discussion of the current limitations and future prospects. The exploration and optimization of the stiffness-tunable biomaterials has the potential to markedly advance the development of neural tissue engineering.展开更多
Direct coaptation of contralateral C7 to the upper trunk could avoid the interposition of nerve grafts. We have successfully shortened the gap and graft lengths, and even achieved direct coaptation. However, direct re...Direct coaptation of contralateral C7 to the upper trunk could avoid the interposition of nerve grafts. We have successfully shortened the gap and graft lengths, and even achieved direct coaptation. However, direct repair can only be performed in some selected cases, and partial procedures still require autografts, which are the gold standard for repairing neurologic defects. As symptoms often occur after autografting, human acellular nerve allografts have been used to avoid concomitant symptoms. This study investigated the quality of shoulder abduction and elbow flexion following direct repair and acellular allografting to evaluate issues requiring attention for brachial plexus injury repair. Fifty-one brachial plexus injury patients in the surgical database were eligible for this retrospective study. Patients were divided into two groups according to different surgical methods. Direct repair was performed in 27 patients, while acellular nerve allografts were used to bridge the gap between the contralateral C7 nerve root and upper trunk in 24 patients. The length of the harvested contralateral C7 nerve root was measured intraoperatively. Deltoid and biceps muscle strength, and degrees of shoulder abduction and elbow flexion were examined according to the British Medical Research Council scoring system;meaningful recovery was defined as M3–M5. Lengths of anterior and posterior divisions of the contralateral C7 in the direct repair group were 7.64 ± 0.69 mm and 7.55 ± 0.69 mm, respectively, and in the acellular nerve allografts group were 6.46 ± 0.58 mm and 6.43 ± 0.59 mm, respectively. After a minimum of 4-year follow-up, meaningful recoveries of deltoid and biceps muscles in the direct repair group were 88.89% and 85.19%, respectively, while they were 70.83% and 66.67% in the acellular nerve allografts group. Time to C5/C6 reinnervation was shorter in the direct repair group compared with the acellular nerve allografts group. Direct repair facilitated the restoration of shoulder abduction and elbow flexion. Thus, if direct coaptation is not possible, use of acellular nerve allografts is a suitable option. This study was approved by the Medical Ethical Committee of the First Affiliated Hospital of Sun Yat-sen University, China (Application ID:[2017] 290) on November 14, 2017.展开更多
Presented in this manuscript are conventional electrical engineering tools to model the earth as a rotating electrical machine. Calculations using known parameters of the earth and measured field data has resulted in ...Presented in this manuscript are conventional electrical engineering tools to model the earth as a rotating electrical machine. Calculations using known parameters of the earth and measured field data has resulted in new understanding of the earth’s electrical system and gyroscopic rotation. The material makeup of the inner earth is better understood based on derived permeability and permittivity constants. The planet has been modeled as simple coils and then as a parallel impedance circuit which has led to fundamental insight into planetary speed control and RLC combination for Schumann Resonance of 7.83 Hz. Torque and Voltage Constants and the inverse Speed Constant are calculated using three methods and all compare favorably with Newton’s Gravitational Constant. A helical resonator is referenced and Schumann’s Resonant ideal frequency is calculated and compared with others idealism. A new theory of gravity based on particle velocity selector at the poles is postulated. Two equations are presented as the needed links between Faraday’s electromagnetism and Newtonian physics. Acceleration and Deceleration of earth is explained as a centripetal governor. A new equation for planetary attraction and the attraction of atomic matter is theorized. Rotation of the earth’s electrical coil is explained in terms of the Richardson effect. Electric power transfer from the sun to the planets is proposed via Flux Transfer Events. The impact of this evolving science of electromagnetic modeling of planets will be magnified as the theory is proven, and found to be useful for future generations of engineers and scientists who seek to discover our world and other planets.展开更多
In social tagging systems, users are allowed to label resources with tags, and thus the system builds a personalized tag vocabulary for every user based on their distinct preferences. In order to make the best of the ...In social tagging systems, users are allowed to label resources with tags, and thus the system builds a personalized tag vocabulary for every user based on their distinct preferences. In order to make the best of the personalized characteristic of users’ tagging behavior, firstly the transfer matrix is used in this paper, and the tag distributions of query resources are mapped to users’ query before the recommendation. Meanwhile, we find that only considering the user’s preference model, the method cannot recommend new tags for users. So we utilize the thought of collaborative filtering, and produce the recommend tags based on the query user and his/her nearest neighbors' preference models. The experiments conducted on the Delicious corpus show that our method combining transfer matrix with collaborative filtering produces better recommendation results.展开更多
Contralateral C7 nerve transfer surgery is one of the most important surgical techniques for treating total brachial plexus nerve injury. In the traditional contralateral C7 nerve transfer surgery, the whole ulnar ner...Contralateral C7 nerve transfer surgery is one of the most important surgical techniques for treating total brachial plexus nerve injury. In the traditional contralateral C7 nerve transfer surgery, the whole ulnar nerve on the paralyzed side is harvested for transfer, which completely sacrifices its potential of recovery. In the present, novel study, we report on the anatomical feasibility of a modified contralateral C7 nerve transfer surgery. Ten fresh cadavers (4 males and 6 females) provided by the Department of Anatomy, Histology, and Embryology at the Medical College of Fudan University, China were used in modified contralateral C7 nerve transfer surgery. In this surgical model, only the dorsal and superficial branches of the ulnar nerve and the medial antebrachial cutaneous nerve on the paralyzed side (left) were harvested for grafting the contralateral (right) C7 nerve and the recipient nerves. Both the median nerve and deep branch of the ulnar nerve on the paralyzed (left) side were recipient nerves. To verify the feasibility of this surgery, the distances between each pair of coaptating nerve ends were measured by a vernier caliper. The results validated that starting point of the deep branch of ulnar nerve and the starting point of the medial antebrachial cutaneous nerve at the elbow were close to each other and could be readily anastomosed. We investigated whether the fiber number of donor and recipient nerves matched one another. The axons were counted in sections of nerve segments distal and proximal to the coaptation sites after silver impregnation. Averaged axon number of the ulnar nerve at the upper arm level was approximately equal to the sum of the median nerve and proximal end of medial antebrachial cutaneous nerve (left: 0.94:1;right: 0.93:1). In conclusion, the contralateral C7 nerve could be transferred to the median nerve but also to the deep branch of the ulnar nerve via grafts of the ulnar nerve without deep branch and the medial antebrachial cutaneous nerve. The advantage over traditional surgery was that the recovery potential of the deep branch of ulnar nerve was preserved. The study was approved by the Ethics Committee of Fudan University (approval number: 2015-064) in July, 2015.展开更多
The transfer matrix of wrist force sensor is important for decoupling theoutput signals and enhancing the precision of wrist force sensor.This paper solves thetransfer matrix from the realization of optimal approximat...The transfer matrix of wrist force sensor is important for decoupling theoutput signals and enhancing the precision of wrist force sensor.This paper solves thetransfer matrix from the realization of optimal approximation of polynomial.First,thegeneral transfer matrix algorithm in the sense of L^2 and two kinds of modified algorithmare proposed.Then,starting from uniform approximation,the optimal transfer matrixalgorithm is offered and solved by the use of linear programming.The results of experi-ment and computation prove that these algorithms are effective.展开更多
In this paper, the analytical transfer matrix method (ATMM) is applied to study the properties of quantum reflection in three systems: a sech2 barrier, a ramp potential and an inverse harmonic oscillator. Our resul...In this paper, the analytical transfer matrix method (ATMM) is applied to study the properties of quantum reflection in three systems: a sech2 barrier, a ramp potential and an inverse harmonic oscillator. Our results agree with those obtained by Landau and Lifshitz [Landau L D and Lifshitz E M 1977 Quantum Mechanics (Non-relativistic Theory) (New York: Pergamon)], which proves that ATMM is a simple and effective method for quantum reflection.展开更多
Operating an Agilent 7700X ICP-MS spectrometer under robust plasma conditions (1550 W) with a He-filled octopole collision cell and analysing solutions (?1 total dissolved solids) still suffered analyte peak suppressi...Operating an Agilent 7700X ICP-MS spectrometer under robust plasma conditions (1550 W) with a He-filled octopole collision cell and analysing solutions (?1 total dissolved solids) still suffered analyte peak suppression due to matrix effects. International reference rocks BCR-1, BHVO-1, AGV-1, G-2 and BCR-2 all showed count rate reductions for 36 elements (mass range 7Li to 238U) averaging ~10% but with no dependence on isotope mass. Use of an internal standard (103Rh) and/or using a ten-fold dilution of sample solutions reduced these effects but problems with reduced count rates combined with larger errors for some elements introduced other problems. The best approach was to normalise the count rates for each element in the other samples against those for BCR-1 as an external standard;thus the count suppression due to the matrix effect is corrected for each individual element. This approach provides standardization “traceability” in line with the ERM ISO/IEC requirement. Experiments are also reported on quantifying the proportions of Ba and selected REE oxide/hydroxide components versus parent isotopes (XO/X and XOH/X). This information is essential for correcting peak interferences on higher mass number REE for the rock samples, and equations are developed to use measured CeO/Ce and CeOH/Ce ratios to predict such values for any other member of the REE suite. Concentrations obtained show excellent agreement with recommended values for the international reference materials especially for the REE. Robust data are also provided for two other standard rocks: nepheline syenite STM-1 and quartz syenite CAAS-1;the latter shows exceptional enrichments of Zr, REE, Th, and U.展开更多
文摘Let p be a prime. For any finite p-group G, the deep transfers T H,G ' : H / H ' → G ' / G " from the maximal subgroups H of index (G:H) = p in G to the derived subgroup G ' are introduced as an innovative tool for identifying G uniquely by means of the family of kernels ùd(G) =(ker(T H,G ')) (G: H) = p. For all finite 3-groups G of coclass cc(G) = 1, the family ùd(G) is determined explicitly. The results are applied to the Galois groups G =Gal(F3 (∞)/ F) of the Hilbert 3-class towers of all real quadratic fields F = Q(√d) with fundamental discriminants d > 1, 3-class group Cl3(F) □ C3 × C3, and total 3-principalization in each of their four unramified cyclic cubic extensions E/F. A systematic statistical evaluation is given for the complete range 1 d 7, and a few exceptional cases are pointed out for 1 d 8.
文摘In this paper the Expendable Pattern Casting with dry sand Vacuum(EPC-V) process is used to manufacture iron matrix composites with tungsten carbide particle.Microstructures of the composites layers were analyzed.The abrasive wear resistance of the composites layers were tested and compared with that of high chromium cast iron.The results show that the iron matrix composites with tungsten carbide particle have high hardness.The abrasive wear resistance of composites with tungsten carbide particle is higher than that of high chromium cast iron.The properties of the matrix materials have been improved remarkably.
基金Supported by National Natural Science Foundation(40661002)Project of National Natural Science Youth Foundation(40701188)Highlevel Talents Initiation Project of Shihezi University(RCZX200693)~~
文摘The most significant changes of landscape in a certain period are landscape area changes and spatial changes of landscape patches.Based on transfer matrix and total amount change of landscape area,landscape space transfer index and landscape area change index were established,and then applied to analyze plain oasis and desert in Yutian County,Xinjiang Uyghur Nationality Autonomous Region,the results showed that landscape space transfer in this region was drastic,but total landscape area changed only slightly,thus space transfer index was much higher than area change index,which indicated that landscapes in arid area were given with particular spatial undulant features and sensitivity,while man-made landscapes(artificial oasis) are stable and expanding to some extent.With landscape space transfer index as the comprehensive indicator,space transfer intensity of landscape within a certain period can be demonstrated,which is favorable for the comparison of landscape change intensity among different types and within different periods,in addition,some macroscopic change features of landscapes can also be reflected by comprehensively analyzing landscape space transfer index and landscape area change index.
文摘IgG Check calf test has been used in this study to identify if a failure of passive transfer occurs in neonatal calves by measuring the level of IgG in blood. An adequate level of IgG measured in all calves at 48 hours, 7 days and 14 days after birth showed level of IgG 1000 mg/dl. This level indicated that they have good passive transfer of immunity. Also, in this study colostrum quality fed to calves was detected using Brix Refractometer. The colostrum is of high quality as it contains 50 mg/ml of IgG. This Brix refractometer can be used on the farm level to estimate colostrum IgG content and monitoring colostrum feeding practices. Colostrum with high quality IgG could provide calves with enough IgG to attain successful passive transfer of immunity. Brix and Obione refractometers provide simple, rapid method for estimating IgG concentration on calf serum, thus considered to be the most common method for determining passive transfer failure.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11574115 and 11704146)
文摘We theoretically investigate the excited state intramolecular proton transfer(ESIPT) behavior of the novel fluorophore bis-imine derivative molecule HNP which was designed based on the intersection of 1-(hydrazonomethyl)-naphthalene-2-ol and 1-pyrenecarboxaldehyde. Especially, the density functional theory(DFT) and time-dependent density functional theory(TDDFT) methods for HNP monomer are introduced. Moreover, the "our own n-layered integrated molecular orbital and molecular mechanics"(ONIOM) method(TDDFT:universal force field(UFF)) is used to reveal the aggregation-induced emission(AIE) effect on the ESIPT process for HNP in crystal. Our results confirm that the ESIPT process happens upon the photoexcitation for the HNP monomer and HNP in crystal, which is distinctly monitored by the optimized geometric structures and the potential energy curves. In addition, the results of potential energy curves reveal that the ESIPT process in HNP will be promoted by the AIE effect. Furthermore, the highest occupied molecular orbital(HOMO) and lowest unoccupied molecular orbital(LUMO) for the HNP monomer and HNP in crystal have been calculated. The calculation demonstrates that the electron density decrease of proton donor caused by excitation promotes the ESIPT process. In addition, we find that the variation of atomic dipole moment corrected Hirshfeld population(ADCH) charge for proton acceptor induced by the AIE effect facilitates the ESIPT process. The results will be expected to deepen the understanding of ESIPT dynamics for luminophore under the AIE effect and provide insight into future design of high-efficient AIE compounds.
文摘This present paper deals with a mathematical description of linear axial and torsional vibrations. The normal and tangential stress tensor components produced by axial-torsional deformations and vibrations in the propeller and intermediate shafts, under the influence of propeller-induced static and variable hydrodynamic excitations are also studied. The transfer matrix method related to the constant coefficients of differential equation solutions is used. The advantage of the latter as compared with a well-known method of transfer matrix associated with state vector is the possibility of reducing the number of multiplied matrices when adjacent shaft segments have the same material properties and diameters. The results show that there is no risk of buckling and confirm that the strength of the shaft line depends on the value of the static tangential stresses which is the most important component of the stress tensor.
文摘Objectives: To describe the versatility of acellular fetal bovine dermal matrix as an alternative to human cadaveric allograft for head and neck reconstructive procedures in children. Study Design: Case series with chart review. Methods: A database of pediatric operative procedures was queried for the use of acellular fetal bovine dermal matrix over a 16-month period. Indications for reconstruction were assessed and initial parental and surgeon satisfaction with the product were noted. Results: During the time period of 3/2012 and 7/2013 a total of 8 reconstructive procedures were performed on pediatric patients using acellular fetal bovine dermal matrix. Indications for use varied and included open and transnasal endoscopic repair of encephaloceles and soft tissue reconstructions including lateral pharyngeal wall repair, cleft palate repair, and facial recontouring operations. Acellular fetal bovine dermal matrix had a subjectively increased ease of use as compared to the surgeon’s prior experience with human cadaveric acellular dermis. Every parent vocalized a greater comfort level with the use of a bovine product over the alternative of human cadaveric tissue. The cost of acellular fetal bovine dermal matrix is slightly lower than the cost of human cadaveric acellular dermis. Conclusions: Acellular fetal bovine dermal matrix appears to be an acceptable alternative to human cadaveric acellular dermis for various forms of head and neck soft tissue reconstruction in children. Further prospective studies are warranted to assess for any differences in the long-term efficacy of this product as compared to other forms of allograft reconstruction.
文摘In this paper the results of dynamic NMR studies on ethylmethylamino-tertiary-butyl-phenylborane (EMABPB) with or without light are reported. The NMR data were recorded on a Bruker 400 MHz NMR equipped with our custom-made optical probe and with our custom-made 450 watts (W) monochromatic light sources. The molecular photochemistry including twisted intramolecular charge-transfer-excited-state (TICT) of the EMABPB in several solvents has been investigated. These results indicate that the aminoborane demonstrates multiple configurations in CD3Cl and CD2Cl2 resulting in the shifts of the signals of the alkyl groups on the nitrogen and boron. This indicates that there are some time-dependent changes at constant temperature over the irradiation interval. At ﹣60°C and the presence of light (λ = 265 nm), we observed a large change in the populations of the two sites, and this by itself indicates a modification in the rotation around the boron nitrogen bond in the excited state. By considering the existence of the TICT state, many important energy technologies may be developed with higher efficiency by controlling the back-electron transfer processes.
基金Supported by Past and present funding in the senior author’s laboratory as follows--Health Research Board of Ireland(HRA--POR-2014-545HRA/2009/49+6 种基金RP/2006/95,to Hopkins AM)Science Foundation Ireland(13/IA/19942008/RFP/NSC14272008/RFP/NSC1427 TIDA Feasibility 10,to Hopkins AM)Cancer Research Ireland,Breast Cancer IrelandBrazil Science Without Borders(CAPES-13306-13-8)the Beaumont Hospital Cancer Research and Development Trust
文摘Cell-cell and cell-matrix signaling and communication between adhesion sites involve mechanisms which are required for cellular functions during normal development and homeostasis; however these cellular functions and mechanisms are often deregulated in cancer. Aberrant signaling at cell-cell and cell-matrix adhesion sites often involves downstream mediators including Rho GTPases and tyrosine kinases. This review discusses these molecules as putative mediators of cellular crosstalk between cell-cell and cell-matrix adhesion sites, in addition to their attractiveness as therapeutic targets in cancer. Interestingly, inter-junctional crosstalk mechanisms are frequently typified by the way in which bacterial and viral pathogens opportunistically infect or intoxicate mammalian cells. This review therefore also discusses the concept of learning from pathogen-host interaction studies to better understand coordinated communication between cell-cell and cell-matrix adhesion sites, in addition to highlighting the potential therapeutic usefulness of exploiting pathogens or their products to tap into inter-junctional crosstalk. Taken together, we feel that increased knowledge around mechanisms of cell-cell and cell-matrix adhesion site crosstalk and consequently a greater understanding of their therapeutic targeting offers a unique opportunity to contribute to the emerging molecular revolution in cancer biology.
文摘The present pagination reports both Brownian diffusion and thermophoresis aspects subject to magneto hydrodynamic Williamson fluid model.Assuming the flow is unsteady and blood is treated as Williamson fluid over a wedge with radiation.The governing equations are transformed into ordinary differential equations by using similarity variables.The analytical solutions of the transformed governing equations are obtained by using the RK 4th order method along with shooting technique solver.The effects of various physical parameters such as Hartmann number,local Weissenberg number,radiation parameter,unsteadiness parameter,Prandtl number,Lewis number,Brownian diffusion,thermophoresis,wedge angle parameter,moving wedge parameter,on velocity,temperature,concentration,skin friction,heat transfer rate and mass transfer rate have been discussed in detail.The velocity and temperature profile deprives for larger We and an opposite trend is observed for concentration.The radiation parameter is propositional to temperature and a counter behaviour is observed for Pr.
基金supported by the Natural Science Foundation of Shandong Province,No.ZR2023MC168the National Natural Science Foundation of China,No.31670989the Key R&D Program of Shandong Province,No.2019GSF107037(all to CS).
文摘Vascular endothelial growth factor and its mimic peptide KLTWQELYQLKYKGI(QK)are widely used as the most potent angiogenic factors for the treatment of multiple ischemic diseases.However,conventional topical drug delivery often results in a burst release of the drug,leading to transient retention(inefficacy)and undesirable diffusion(toxicity)in vivo.Therefore,a drug delivery system that responds to changes in the microenvironment of tissue regeneration and controls vascular endothelial growth factor release is crucial to improve the treatment of ischemic stroke.Matrix metalloproteinase-2(MMP-2)is gradually upregulated after cerebral ischemia.Herein,vascular endothelial growth factor mimic peptide QK was self-assembled with MMP-2-cleaved peptide PLGLAG(TIMP)and customizable peptide amphiphilic(PA)molecules to construct nanofiber hydrogel PA-TIMP-QK.PA-TIMP-QK was found to control the delivery of QK by MMP-2 upregulation after cerebral ischemia/reperfusion and had a similar biological activity with vascular endothelial growth factor in vitro.The results indicated that PA-TIMP-QK promoted neuronal survival,restored local blood circulation,reduced blood-brain barrier permeability,and restored motor function.These findings suggest that the self-assembling nanofiber hydrogel PA-TIMP-QK may provide an intelligent drug delivery system that responds to the microenvironment and promotes regeneration and repair after cerebral ischemia/reperfusion injury.
文摘The dynamic stiffness method and Transfer method is applied to study the vibration characteristics of the Euler-Bernoulli pipe conveying fluid in this paper. According to the dynamics equation of the pipe conveying fluid, the element dynamic stiffness is established. The vibration characteristic of the single-span pipe is analyzed under two kinds of boundary conditions. The results compared with the literature, which has a good consistency. Based on this method, natural frequency and the critical speed of the two types of multi-span pipe are deserved. This paper shows that the dynamic stiffness method and transfer matrix is an effective method to deal with the vibration problem of pipe conveying fluid.
基金supported by the Natio`nal Natural Science Foundation of China,No. 81801241a grant from Sichuan Science and Technology Program,No. 2023NSFSC1578Scientific Research Projects of Southwest Medical University,No. 2022ZD002 (all to JX)。
文摘Neuronal growth, extension, branching, and formation of neural networks are markedly influenced by the extracellular matrix—a complex network composed of proteins and carbohydrates secreted by cells. In addition to providing physical support for cells, the extracellular matrix also conveys critical mechanical stiffness cues. During the development of the nervous system, extracellular matrix stiffness plays a central role in guiding neuronal growth, particularly in the context of axonal extension, which is crucial for the formation of neural networks. In neural tissue engineering, manipulation of biomaterial stiffness is a promising strategy to provide a permissive environment for the repair and regeneration of injured nervous tissue. Recent research has fine-tuned synthetic biomaterials to fabricate scaffolds that closely replicate the stiffness profiles observed in the nervous system. In this review, we highlight the molecular mechanisms by which extracellular matrix stiffness regulates axonal growth and regeneration. We highlight the progress made in the development of stiffness-tunable biomaterials to emulate in vivo extracellular matrix environments, with an emphasis on their application in neural repair and regeneration, along with a discussion of the current limitations and future prospects. The exploration and optimization of the stiffness-tunable biomaterials has the potential to markedly advance the development of neural tissue engineering.
基金supported by the National Natural Science Foundation of China,No.81572130(to LQG)and 81601057(to JTY)the National Key Research and Development Plan of China,No.2016YFC1101603(to XLL)the Natural Science Foundation of Guangdong Province of China,No.2015A030310350(to JTY)
文摘Direct coaptation of contralateral C7 to the upper trunk could avoid the interposition of nerve grafts. We have successfully shortened the gap and graft lengths, and even achieved direct coaptation. However, direct repair can only be performed in some selected cases, and partial procedures still require autografts, which are the gold standard for repairing neurologic defects. As symptoms often occur after autografting, human acellular nerve allografts have been used to avoid concomitant symptoms. This study investigated the quality of shoulder abduction and elbow flexion following direct repair and acellular allografting to evaluate issues requiring attention for brachial plexus injury repair. Fifty-one brachial plexus injury patients in the surgical database were eligible for this retrospective study. Patients were divided into two groups according to different surgical methods. Direct repair was performed in 27 patients, while acellular nerve allografts were used to bridge the gap between the contralateral C7 nerve root and upper trunk in 24 patients. The length of the harvested contralateral C7 nerve root was measured intraoperatively. Deltoid and biceps muscle strength, and degrees of shoulder abduction and elbow flexion were examined according to the British Medical Research Council scoring system;meaningful recovery was defined as M3–M5. Lengths of anterior and posterior divisions of the contralateral C7 in the direct repair group were 7.64 ± 0.69 mm and 7.55 ± 0.69 mm, respectively, and in the acellular nerve allografts group were 6.46 ± 0.58 mm and 6.43 ± 0.59 mm, respectively. After a minimum of 4-year follow-up, meaningful recoveries of deltoid and biceps muscles in the direct repair group were 88.89% and 85.19%, respectively, while they were 70.83% and 66.67% in the acellular nerve allografts group. Time to C5/C6 reinnervation was shorter in the direct repair group compared with the acellular nerve allografts group. Direct repair facilitated the restoration of shoulder abduction and elbow flexion. Thus, if direct coaptation is not possible, use of acellular nerve allografts is a suitable option. This study was approved by the Medical Ethical Committee of the First Affiliated Hospital of Sun Yat-sen University, China (Application ID:[2017] 290) on November 14, 2017.
文摘Presented in this manuscript are conventional electrical engineering tools to model the earth as a rotating electrical machine. Calculations using known parameters of the earth and measured field data has resulted in new understanding of the earth’s electrical system and gyroscopic rotation. The material makeup of the inner earth is better understood based on derived permeability and permittivity constants. The planet has been modeled as simple coils and then as a parallel impedance circuit which has led to fundamental insight into planetary speed control and RLC combination for Schumann Resonance of 7.83 Hz. Torque and Voltage Constants and the inverse Speed Constant are calculated using three methods and all compare favorably with Newton’s Gravitational Constant. A helical resonator is referenced and Schumann’s Resonant ideal frequency is calculated and compared with others idealism. A new theory of gravity based on particle velocity selector at the poles is postulated. Two equations are presented as the needed links between Faraday’s electromagnetism and Newtonian physics. Acceleration and Deceleration of earth is explained as a centripetal governor. A new equation for planetary attraction and the attraction of atomic matter is theorized. Rotation of the earth’s electrical coil is explained in terms of the Richardson effect. Electric power transfer from the sun to the planets is proposed via Flux Transfer Events. The impact of this evolving science of electromagnetic modeling of planets will be magnified as the theory is proven, and found to be useful for future generations of engineers and scientists who seek to discover our world and other planets.
文摘In social tagging systems, users are allowed to label resources with tags, and thus the system builds a personalized tag vocabulary for every user based on their distinct preferences. In order to make the best of the personalized characteristic of users’ tagging behavior, firstly the transfer matrix is used in this paper, and the tag distributions of query resources are mapped to users’ query before the recommendation. Meanwhile, we find that only considering the user’s preference model, the method cannot recommend new tags for users. So we utilize the thought of collaborative filtering, and produce the recommend tags based on the query user and his/her nearest neighbors' preference models. The experiments conducted on the Delicious corpus show that our method combining transfer matrix with collaborative filtering produces better recommendation results.
基金supported by the National Natural Science Foundation of China,No.81572127(to JL)
文摘Contralateral C7 nerve transfer surgery is one of the most important surgical techniques for treating total brachial plexus nerve injury. In the traditional contralateral C7 nerve transfer surgery, the whole ulnar nerve on the paralyzed side is harvested for transfer, which completely sacrifices its potential of recovery. In the present, novel study, we report on the anatomical feasibility of a modified contralateral C7 nerve transfer surgery. Ten fresh cadavers (4 males and 6 females) provided by the Department of Anatomy, Histology, and Embryology at the Medical College of Fudan University, China were used in modified contralateral C7 nerve transfer surgery. In this surgical model, only the dorsal and superficial branches of the ulnar nerve and the medial antebrachial cutaneous nerve on the paralyzed side (left) were harvested for grafting the contralateral (right) C7 nerve and the recipient nerves. Both the median nerve and deep branch of the ulnar nerve on the paralyzed (left) side were recipient nerves. To verify the feasibility of this surgery, the distances between each pair of coaptating nerve ends were measured by a vernier caliper. The results validated that starting point of the deep branch of ulnar nerve and the starting point of the medial antebrachial cutaneous nerve at the elbow were close to each other and could be readily anastomosed. We investigated whether the fiber number of donor and recipient nerves matched one another. The axons were counted in sections of nerve segments distal and proximal to the coaptation sites after silver impregnation. Averaged axon number of the ulnar nerve at the upper arm level was approximately equal to the sum of the median nerve and proximal end of medial antebrachial cutaneous nerve (left: 0.94:1;right: 0.93:1). In conclusion, the contralateral C7 nerve could be transferred to the median nerve but also to the deep branch of the ulnar nerve via grafts of the ulnar nerve without deep branch and the medial antebrachial cutaneous nerve. The advantage over traditional surgery was that the recovery potential of the deep branch of ulnar nerve was preserved. The study was approved by the Ethics Committee of Fudan University (approval number: 2015-064) in July, 2015.
文摘The transfer matrix of wrist force sensor is important for decoupling theoutput signals and enhancing the precision of wrist force sensor.This paper solves thetransfer matrix from the realization of optimal approximation of polynomial.First,thegeneral transfer matrix algorithm in the sense of L^2 and two kinds of modified algorithmare proposed.Then,starting from uniform approximation,the optimal transfer matrixalgorithm is offered and solved by the use of linear programming.The results of experi-ment and computation prove that these algorithms are effective.
基金Project supported by Science Foundation of Nantong University (Grant Nos. 03080122 and 09ZY001)
文摘In this paper, the analytical transfer matrix method (ATMM) is applied to study the properties of quantum reflection in three systems: a sech2 barrier, a ramp potential and an inverse harmonic oscillator. Our results agree with those obtained by Landau and Lifshitz [Landau L D and Lifshitz E M 1977 Quantum Mechanics (Non-relativistic Theory) (New York: Pergamon)], which proves that ATMM is a simple and effective method for quantum reflection.
文摘Operating an Agilent 7700X ICP-MS spectrometer under robust plasma conditions (1550 W) with a He-filled octopole collision cell and analysing solutions (?1 total dissolved solids) still suffered analyte peak suppression due to matrix effects. International reference rocks BCR-1, BHVO-1, AGV-1, G-2 and BCR-2 all showed count rate reductions for 36 elements (mass range 7Li to 238U) averaging ~10% but with no dependence on isotope mass. Use of an internal standard (103Rh) and/or using a ten-fold dilution of sample solutions reduced these effects but problems with reduced count rates combined with larger errors for some elements introduced other problems. The best approach was to normalise the count rates for each element in the other samples against those for BCR-1 as an external standard;thus the count suppression due to the matrix effect is corrected for each individual element. This approach provides standardization “traceability” in line with the ERM ISO/IEC requirement. Experiments are also reported on quantifying the proportions of Ba and selected REE oxide/hydroxide components versus parent isotopes (XO/X and XOH/X). This information is essential for correcting peak interferences on higher mass number REE for the rock samples, and equations are developed to use measured CeO/Ce and CeOH/Ce ratios to predict such values for any other member of the REE suite. Concentrations obtained show excellent agreement with recommended values for the international reference materials especially for the REE. Robust data are also provided for two other standard rocks: nepheline syenite STM-1 and quartz syenite CAAS-1;the latter shows exceptional enrichments of Zr, REE, Th, and U.