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气象观测场在汽车试验场中的应用研究
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作者 陈海建 《时代汽车》 2024年第14期172-174,178,共4页
汽车试验场作为汽车开展道路测试的重要场所,用于验证汽车产品的品质以及可靠性。除了场地道路外,气象条件作为汽车道路测试的重要一环,在《GB/T12534-1990汽车道路试验方法通则》中也有明确要求,如:试验时应是无雨无雾天气,相对湿度小... 汽车试验场作为汽车开展道路测试的重要场所,用于验证汽车产品的品质以及可靠性。除了场地道路外,气象条件作为汽车道路测试的重要一环,在《GB/T12534-1990汽车道路试验方法通则》中也有明确要求,如:试验时应是无雨无雾天气,相对湿度小于95%,气温0-40℃,风速不大于3m/s。同时气象条件也作为试验场道路管控的重要依据,实时风速、雨量、能见度等信息为场地管理者发布限速、限行、封场等通知提供必要参考依据,直接影响道路测试安全管控的及时性。因此,文章从气象观测场的建设、气象服务、异常天气道路管控等方面开展气象观测场在汽车试验场中的应用研究。 展开更多
关键词 products. In addition to the SITE roads METEOROLOGICAL conditions are an important part of AUTOMOTIVE ROAD testing and there are also clear requirements in the GB/T12534-1990 General Rules for AUTOMOTIVE ROAD Test Methods. For example the test should be conducted in rain and fog free weather with a relative humidity of less than 95% a temperature of 0-40 and a wind SPEED of no more than 3m/s. At the same time METEOROLOGICAL conditions also serve as an important basis for ROAD control in the test site. Real time information such as wind SPEED rainfall and visibility provides necessary reference for SITE managers to issue notices on SPEED limits SITE closures and trac restrictions directly aecting the timeliness of ROAD testing safety control. Therefore this article conducts research on the application of METEOROLOGICAL observation SITES in AUTOMOTIVE testing SITES from the construction of METEOROLOGICAL observation SITES METEOROLOGICAL services and abnormal weather ROAD control.
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Mathematical Wave Functions and 3D Finite Element Modelling of the Electron and Positron
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作者 Declan Traill 《Journal of Applied Mathematics and Physics》 2024年第4期1134-1162,共29页
The wave/particle duality of particles in Physics is well known. Particles have properties that uniquely characterize them from one another, such as mass, charge and spin. Charged particles have associated Electric an... The wave/particle duality of particles in Physics is well known. Particles have properties that uniquely characterize them from one another, such as mass, charge and spin. Charged particles have associated Electric and Magnetic fields. Also, every moving particle has a De Broglie wavelength determined by its mass and velocity. This paper shows that all of these properties of a particle can be derived from a single wave function equation for that particle. Wave functions for the Electron and the Positron are presented and principles are provided that can be used to calculate the wave functions of all the fundamental particles in Physics. Fundamental particles such as electrons and positrons are considered to be point particles in the Standard Model of Physics and are not considered to have a structure. This paper demonstrates that they do indeed have structure and that this structure extends into the space around the particle’s center (in fact, they have infinite extent), but with rapidly diminishing energy density with the distance from that center. The particles are formed from Electromagnetic standing waves, which are stable solutions to the Schrödinger and Classical wave equations. This stable structure therefore accounts for both the wave and particle nature of these particles. In fact, all of their properties such as mass, spin and electric charge, can be accounted for from this structure. These particle properties appear to originate from a single point at the center of the wave function structure, in the same sort of way that the Shell theorem of gravity causes the gravity of a body to appear to all originate from a central point. This paper represents the first two fully characterized fundamental particles, with a complete description of their structure and properties, built up from the underlying Electromagnetic waves that comprise these and all fundamental particles. 展开更多
关键词 ELECTRON POSITRON Wave Function Solution Electromagnetic Spin Mass Charge Proof Fundamental Particle Properties Quantum Mechanics Classical Physics Computer 3D Model Schrödinger Equation RMS KLEIN GORDON Electric Magnetic Lorentz Invariant Hertzian vector Point Potential Field Density Phase Flow Attraction REPULSION Shell Theorem Ehrenfest VIRIAL Normalization Harmonic Oscillator
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Human Habitats and Malaria Vector Control in Benin: Current Situation and Implications for Effective Control
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作者 Barikissou G. Damien Armel Djènontin +1 位作者 Badirou Aguemon Franck Remoué 《Advances in Infectious Diseases》 2023年第4期706-721,共16页
Long-lasting insecticide-treated nets (LLINs) and indoor residual spraying (IRS) are the main indoor malaria vector tools control tools. The study examined housing characteristics and investigated the relationship bet... Long-lasting insecticide-treated nets (LLINs) and indoor residual spraying (IRS) are the main indoor malaria vector tools control tools. The study examined housing characteristics and investigated the relationship between the total volume of household possessions, the volume of the sleeping room, and the hanging of LLINs. A total of 831 bedrooms were randomly selected in Benin in 2015. The findings showed that mud walls were predominant in rural areas (more than 75%), while metal roofs were common (77.3% - 97.9%). Battery-powered lighting was prevalent in rural areas in Northern (97%), while open-flame oil lamps were commonly used in rural areas in Southern (86%). The availability of correct bedding was low, ranging from 1% to 10% in all households. 20% of the bedrooms had at least 50% of their volume occupied by household possessions in urban areas. In rural areas, bedrooms without LLINs had a lower mean rate ratio of the volume occupied by possessions per the total volume of the room compared to bedrooms with at least one LLIN installed (p < 0.0001). The characteristics of human habitats are not favourable to the correct use of vector control intervention indoors. It is therefore important to improve people’s living conditions as the next step for malaria elimination. 展开更多
关键词 HOUSING LIGHTING BEDDING Possessions Malaria vector control LLINs IRS
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Advancement in Wide Area Monitoring Protection and Control Using PMU’s Model in MATLAB/SIMULINK
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作者 Waheed Ur Rahman Muhammad Ali +7 位作者 Amjad Ullah Hafeez Ur Rahman Majid Iqbal Haseeb Ahmad Adnan Zeb Zeeshan Ali M. Ahsan Shahzad Beenish Taj 《Smart Grid and Renewable Energy》 2012年第4期294-307,共14页
A big step forward to improve power system monitoring and performance, continued load growth without a corresponding increase in transmission resources has resulted in reduced operational margins for many power system... A big step forward to improve power system monitoring and performance, continued load growth without a corresponding increase in transmission resources has resulted in reduced operational margins for many power systems worldwide and has led to operation of power systems closer to their stability limits and to power exchange in new patterns. These issues, as well as the on-going worldwide trend towards deregulation of the entire industry on the one hand and the increased need for accurate and better network monitoring on the other hand, force power utilities exposed to this pressure to demand new solutions for wide area monitoring, protection and control. Wide-area monitoring, protection, and control require communicating the specific-node information to a remote station but all information should be time synchronized so that to neutralize the time difference between information. It gives a complete simultaneous snap shot of the power system. The conventional system is not able to satisfy the time-synchronized requirement of power system. Phasor Measurement Unit (PMU) is enabler of time-synchronized measurement, it communicate the synchronized local information to remote station. 展开更多
关键词 WIDE Area MONITORING Protection and control (WAMPAC) Phasor Measurement uNit (PMU) WIDE Area MONITORING (WAM) Global Positioning System (GPS) WIDE Area controlLER (WAC) Local Area controlLER (LAC) Phase Angle MONITORING (PAM) Automatic Generation control (AGC) Circuit Breaker (CB) Current TRANSFORMERS (CTs) Potential TRANSFORMERS (PTs)
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Indirect Vector Control of Linear Induction Motors Using Space Vector Pulse Width Modulation 被引量:1
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作者 Arjmand Khaliq Syed Abdul Rahman Kashif +5 位作者 Fahad Ahmad Muhammad Anwar Qaisar Shaheen Rizwan Akhtar Muhammad Arif Shah Abdelzahir Abdelmaboud 《Computers, Materials & Continua》 SCIE EI 2023年第3期6263-6287,共25页
Vector control schemes have recently been used to drive linear induction motors(LIM)in high-performance applications.This trend promotes the development of precise and efficient control schemes for individual motors.T... Vector control schemes have recently been used to drive linear induction motors(LIM)in high-performance applications.This trend promotes the development of precise and efficient control schemes for individual motors.This research aims to present a novel framework for speed and thrust force control of LIM using space vector pulse width modulation(SVPWM)inverters.The framework under consideration is developed in four stages.To begin,MATLAB Simulink was used to develop a detailed mathematical and electromechanical dynamicmodel.The research presents a modified SVPWM inverter control scheme.By tuning the proportional-integral(PI)controller with a transfer function,optimized values for the PI controller are derived.All the subsystems mentioned above are integrated to create a robust simulation of the LIM’s precise speed and thrust force control scheme.The reference speed values were chosen to evaluate the performance of the respective system,and the developed system’s response was verified using various data sets.For the low-speed range,a reference value of 10m/s is used,while a reference value of 100 m/s is used for the high-speed range.The speed output response indicates that themotor reached reference speed in amatter of seconds,as the delay time is between 8 and 10 s.The maximum amplitude of thrust achieved is less than 400N,demonstrating the controller’s capability to control a high-speed LIM with minimal thrust ripple.Due to the controlled speed range,the developed system is highly recommended for low-speed and high-speed and heavy-duty traction applications. 展开更多
关键词 Space vector pulse width modulation linear induction motor proportional-integral controller indirect vector control electromechanical dynamic modeling
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Evaluation of Malaria Transmission and Vector Control Strategies in the Dry Season in the Cotonou V Health Zone, Benin, West Africa
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作者 Tokponnon Filémon Osse Razaki +6 位作者 Zannou Ahissou Robert Franck Alapini Marlène Sare Dabou Zoulkifilou Houessinon Festus Gounou Yerima Idayath Sominahoun André Akogbeto Martin 《Advances in Entomology》 2023年第3期156-171,共16页
The anarchic urbanization of certain African cities favors the multiplication of the malaria parasite. Thus, the urgent mobilization of African cities is essential to combat this health risk. It is, therefore, with th... The anarchic urbanization of certain African cities favors the multiplication of the malaria parasite. Thus, the urgent mobilization of African cities is essential to combat this health risk. It is, therefore, with the objective of contributing to the investigation of problem areas that the present study evaluates malaria transmission and vector control strategies in the Cotonou V health zone in particular. This is a cross-sectional study taking into account four neighborhoods, including Wologuèdè, Sainte Rita, Gbèdjromèdé and the area around Etoile Rouge. Two nocturnal captures on voluntary humans and the method of spray were carried out in the dry season from December 2021 to February 2022. On the captured Anopheles, the ELISA Circum-Sporozoite Protein test was performed to determine the infectivity and calculate some transmission parameters. Finally, we conducted a survey using the second stage sampling method with one step to ask selected households about their knowledge of vector control methods, their use and the physical integrity of LLINs. We collected 2386 culicidae of which the majority was Culex quinquefasciatus. After the ELISA test, the 29 Anopheles tested, showed no infectivity, i.e. an EIR of 0 pi/h/n. In addition, 99% of the populations in the Cotonou V area use LLINs to protect themselves. However, coils, door and window screens, aerosol sprays, skin and household repellents, and periodic indoor spraying were used. Finally, the majority of nets observed had T1 tears, but there were also T2, T3 and T4 nets (P-value = 0.0). This study confirms that malaria transmission during the dry season in the Cotonou V health zone is almost negligible but not non-existent. Also, populations are exposed to the nuisance of Culex quinquefasciatus mosquitoes continuously throughout the year. 展开更多
关键词 ANOPHELES Transmission Urban Malaria Cotonou V Health Zone vector control
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Semantic model and optimization of creative processes at mathematical knowledge formation
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作者 Victor Egorovitch Firstov 《Natural Science》 2010年第8期915-922,共8页
The aim of this work is mathematical education through the knowledge system and mathematical modeling. A net model of formation of mathematical knowledge as a deductive theory is suggested here. Within this model the ... The aim of this work is mathematical education through the knowledge system and mathematical modeling. A net model of formation of mathematical knowledge as a deductive theory is suggested here. Within this model the formation of deductive theory is represented as the development of a certain informational space, the elements of which are structured in the form of the orientated semantic net. This net is properly metrized and characterized by a certain system of coverings. It allows injecting net optimization parameters, regulating qualitative aspects of knowledge system under consideration. To regulate the creative processes of the formation and realization of mathematical know- edge, stochastic model of formation deductive theory is suggested here in the form of branching Markovian process, which is realized in the corresponding informational space as a semantic net. According to this stochastic model we can get correct foundation of criterion of optimization creative processes that leads to “great main points” strategy (GMP-strategy) in the process of realization of the effective control in the research work in the sphere of mathematics and its applications. 展开更多
关键词 The Cybernetic Conception Optimization of control Quantitative And Qualitative Information Measures Modelling Intellectual Systems Neural Network MATHEMATICAL Education The control of Pedagogical PROCESSES CREATIVE Pedagogics Cognitive And CREATIVE PROCESSES Informal Axiomatic Thery SEMANTIC NET NET Optimization Parameters The Topology of SEMANTIC NET Metrization The System of Coverings Stochastic Model of CREATIVE PROCESSES At The Formation of MATHEMATICAL Knowledge Branching Markovian Process Great Main Points Strategy (GMP-Strategy) of The CREATIVE PROCESSES control Interdisciplinary Learning: Colorimetric Barycenter
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Adaptive Fuzzy Sliding Mode Controller for Grid Interface Ocean Wave Energy Conversion
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作者 Adel A. A. Elgammal 《Journal of Intelligent Learning Systems and Applications》 2014年第2期53-69,共17页
This paper presents a closed-loop vector control structure based on adaptive Fuzzy Logic Sliding Mode Controller (FL-SMC) for a grid-connected Wave Energy Conversion System (WECS) driven Self-Excited Induction Generat... This paper presents a closed-loop vector control structure based on adaptive Fuzzy Logic Sliding Mode Controller (FL-SMC) for a grid-connected Wave Energy Conversion System (WECS) driven Self-Excited Induction Generator (SEIG). The aim of the developed control method is to automatically tune and optimize the scaling factors and the membership functions of the Fuzzy Logic Controllers (FLC) using Multi-Objective Genetic Algorithms (MOGA) and Multi-Objective Particle Swarm Optimization (MOPSO). Two Pulse Width Modulated voltage source PWM converters with a carrier-based Sinusoidal PWM modulation for both Generator- and Grid-side converters have been connected back to back between the generator terminals and utility grid via common DC link. The indirect vector control scheme is implemented to maintain balance between generated power and power supplied to the grid and maintain the terminal voltage of the generator and the DC bus voltage constant for variable rotor speed and load. Simulation study has been carried out using the MATLAB/Simulink environment to verify the robustness of the power electronics converters and the effectiveness of proposed control method under steady state and transient conditions and also machine parameters mismatches. The proposed control scheme has improved the voltage regulation and the transient performance of the wave energy scheme over a wide range of operating conditions. 展开更多
关键词 GRID integration Wave Energy Conversion Systems Self-Excited Induction Generator (SEIG) vector control Genetic Algorithm (GA) Particle SWARM Optimization (PSO) SLIDING Mode control (SMC) Fuzzy Logic control (FLC) MEMBERSHIP Function Tuning
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Speed Sensorless Vector Control of Induction Motor Based on Reduced Order Extended Kalman Filter 被引量:1
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作者 杨文强 贾正春 许强 《Journal of Southeast University(English Edition)》 EI CAS 2001年第1期41-45,共5页
A speed sensorless vector control system of induction motor with estimated rotor speed and rotor flux using a new reduced order extended Kalman filter is proposed. With this method, two rotor flux components are sele... A speed sensorless vector control system of induction motor with estimated rotor speed and rotor flux using a new reduced order extended Kalman filter is proposed. With this method, two rotor flux components are selected as the state variables, and the rotor speed as an estimated parameter is regarded as an augmented state variable. The algorithm with reduced order decreases the computational complexity and makes the proposed estimator feasible to be implemented in real time. The simulation results show high accuracy of the estimation algorithm and good performance of speed control, and verify the usefulness of the proposed algorithm. 展开更多
关键词 extended Kalman filter flux estimation speed estimation speed sensorless vector control induction motor
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Applications of nanomaterials in mosquito vector control:A review 被引量:1
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作者 Sahadiya Mandodan Aneha Kunnikuruvan +8 位作者 Bhagyashree Bora Hemaladkshmi Padmanaban Abhisubesh Vijayakumar Kakhuangailiu Gangmei Manikandan Sivaprakasam Jibi Lukose Mathivanan Ashokkumar Vijayalakshmi Krishnamoorthy Subbiah Poopathi 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2023年第11期479-489,共11页
The periodic outbreak of mosquito-borne diseases like dengue fever,zika fever,and yellow fever all over the world highlights the need for effective mosquito control methods targeting the biological system.Due to the l... The periodic outbreak of mosquito-borne diseases like dengue fever,zika fever,and yellow fever all over the world highlights the need for effective mosquito control methods targeting the biological system.Due to the lack of therapeutic measures,preventive treatments or vaccines against pathogens,insecticide resistance eventually lead the research focus towards novel technological applications in mosquito management.Nanomaterials with ovicidal,larvicidal,adulticidal,and repellent properties for controlling mosquito vectors are under research.A literature search was carried out for advancements in nanomaterials,insecticides,and mosquito control in PubMed/MEDLINE,Scopus,Google Scholar,ScienceDirect,and Web of Science.This paper aims to provide insights into various nanomaterials relevant to mosquito-borne diseases,in vivo and in vitro toxicity evaluation against mosquito species,mode of action,effect on non-target organisms,and ecological risks.Organic and inorganic materials that provide controlled release,target delivery,less dosage,prolonged efficacy,a reduction in the use of organic solvents and emulsifiers,and minimum pollution to the environment have already been explored.Indeed,further research on the ecological risk and economic feasibility of nanomaterials in mosquitocidal applications should be done prior to commercialization. 展开更多
关键词 NANOMATERIALS Nanoformulation Nanopesticides Mosquito control
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Recent Progress in Reinforcement Learning and Adaptive Dynamic Programming for Advanced Control Applications 被引量:3
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作者 Ding Wang Ning Gao +2 位作者 Derong Liu Jinna Li Frank L.Lewis 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第1期18-36,共19页
Reinforcement learning(RL) has roots in dynamic programming and it is called adaptive/approximate dynamic programming(ADP) within the control community. This paper reviews recent developments in ADP along with RL and ... Reinforcement learning(RL) has roots in dynamic programming and it is called adaptive/approximate dynamic programming(ADP) within the control community. This paper reviews recent developments in ADP along with RL and its applications to various advanced control fields. First, the background of the development of ADP is described, emphasizing the significance of regulation and tracking control problems. Some effective offline and online algorithms for ADP/adaptive critic control are displayed, where the main results towards discrete-time systems and continuous-time systems are surveyed, respectively.Then, the research progress on adaptive critic control based on the event-triggered framework and under uncertain environment is discussed, respectively, where event-based design, robust stabilization, and game design are reviewed. Moreover, the extensions of ADP for addressing control problems under complex environment attract enormous attention. The ADP architecture is revisited under the perspective of data-driven and RL frameworks,showing how they promote ADP formulation significantly.Finally, several typical control applications with respect to RL and ADP are summarized, particularly in the fields of wastewater treatment processes and power systems, followed by some general prospects for future research. Overall, the comprehensive survey on ADP and RL for advanced control applications has d emonstrated its remarkable potential within the artificial intelligence era. In addition, it also plays a vital role in promoting environmental protection and industrial intelligence. 展开更多
关键词 Adaptive dynamic programming(ADP) advanced control complex environment data-driven control event-triggered design intelligent control neural networks nonlinear systems optimal control reinforcement learning(RL)
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Four Algorithms for Boundary Control with Breaking in Space and Time
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作者 Vladimir Arabadzhi 《Journal of Applied Mathematics and Physics》 2019年第11期2891-2901,共11页
Typically, active control systems either have a priori complete information about the boundary-value problem and damped waves before switching on, or get it during the measurement process or accumulate and update info... Typically, active control systems either have a priori complete information about the boundary-value problem and damped waves before switching on, or get it during the measurement process or accumulate and update information online (identification process in adaptive systems). In this case, the boundary problem is completely imprinted in the information arrays of the control system. However, very often complete information about a boundary-value problem is not available in principle or this info is changing in time faster than the process of its accumulation. The article considers examples of boundary control algorithms based almost without any information. The algorithms presented in the article cannot be obtained within the framework of the harmonic representation of the problem by complex amplitudes. And these algorithms carry out fast control in microstructured boundary problems. It is shown that in some cases it is possible to find simple solutions if we remove restrictions: 1) on the spatio-temporal resolution of controlling elements of a boundary-value problem;2) on the high-frequency radiation of the controlled boundary. 展开更多
关键词 INCIDENT Low FREQUENCY Wave High FREQUENCY Technological Radiation Fast control in Microstructured Boundary Problems Binary BREAKER Breaker-Inverter Length of Damping SPINNING Acoustic BLADES Gas Stream SEICHE Waves
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SF VECTOR CONTROL SYSTEM WITH TWO SINGLE CHIP MICROPROCESSORS
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作者 XU Yinquan Cui Gejin (Automation and Computer Science Department) 《Journal of China Textile University(English Edition)》 EI CAS 1990年第2期73-78,共6页
This paper introduces a SF vector control system of a slip frequency controlled induction mo-tor with simple structure,fair performance and convenient operation.It is realized by two singlechip microprocessors and fed... This paper introduces a SF vector control system of a slip frequency controlled induction mo-tor with simple structure,fair performance and convenient operation.It is realized by two singlechip microprocessors and fed from SPWM-GTR inverter.The whole system is combined by twosubsystems,both of them are 8031 single chip microprocessors.The communication between themis coordinated by the full duplex serial port within the chip and ask-and-answer communicationmanner.The error-corrected means adopted has improved the operation reliability of the system.A series of experimental results on a 3 kW induction motor are given at the end of this paper. 展开更多
关键词 vector control SINGLE CHIP MICROPROCESSOR SPWM WAVES
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An Integrated Control Framework for Torque Vectoring and Active Suspension System 被引量:1
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作者 Jiwei Feng Jinhao Liang +6 位作者 Yanbo Lu Weichao Zhuang Dawei Pi Guodong Yin Liwei Xu Pai Peng Chaobin Zhou 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第1期62-73,共12页
Four-wheel independently driven electric vehicles(FWID-EV)endow a flexible and scalable control framework to improve vehicle performance.This paper integrates the torque vectoring and active suspension system(ASS)to e... Four-wheel independently driven electric vehicles(FWID-EV)endow a flexible and scalable control framework to improve vehicle performance.This paper integrates the torque vectoring and active suspension system(ASS)to enhance the vehicle’s longitudinal and vertical motion control performance.While the nonlinear characteristic of the tire model leads to a relatively heavier computational burden.To facilitate the controller design and ease the load,a half-vehicle dynamics system is built and simplified to the linear-time-varying(LTV)model.Then a model predictive controller is developed by formulating the objective function by comprehensively considering the safety,energy-saving and comfort requirements.The in-wheel motor efficiency and the power loss of tire slip are treated as optimization indices in this work to reduce energy consumption.Finally,the effectiveness of the proposed controller is verified through the rapid-control-prototype(RCP)test.The results demonstrate the enhancement of the energy-saving as well as comfort on the basis of vehicle stability. 展开更多
关键词 Four-wheel independently driven electric vehicles Tire nonlinearity Linear-time-varying(LTV)model Model predictive control Rapid control prototype
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Compensation of Dead-Time Effect of Speed Sensorless Vector Control System
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作者 夏超英 张靖 《Transactions of Tianjin University》 EI CAS 2011年第5期351-355,共5页
The key of speed sensorless vector control system lies in the accurate orientation of magnetic field. In some field-oriented algorithms, the integrator of observers and the dead-time effect bring in system errors duri... The key of speed sensorless vector control system lies in the accurate orientation of magnetic field. In some field-oriented algorithms, the integrator of observers and the dead-time effect bring in system errors during the estimation of field position. In this paper, a saturated feedback integrator is used, and the dead-time effect is compen- sated by current positive feedback. Experiments were carried out on the hardware platform of MCK2407, with chip TMS320LF2407 from TI Company. The results show that the prooosed method is simole and effective, and the accuracy of field position is improved. 展开更多
关键词 induction motor speed sensorless vector control DSP COMPENSATION DEAD-TIME field orientation
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Balance control during gait initiation: State-of-the-art and research perspectives 被引量:1
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作者 Eric Yiou Teddy Caderby +2 位作者 Arnaud Delafontaine Paul Fourcade Jean-Louis Honeine 《World Journal of Orthopedics》 2017年第11期815-828,共14页
It is well known that balance control is affected by aging, neurological and orthopedic conditions. Poor balance control during gait and postural maintenance are associated with disability, falls and increased mortali... It is well known that balance control is affected by aging, neurological and orthopedic conditions. Poor balance control during gait and postural maintenance are associated with disability, falls and increased mortality. Gait initiation-the transient period between the quiet standing posture and steady state walking-is a functional task that is classically used in the literature to investigate how the central nervous system(CNS) controls balance during a whole-body movement involving change in the base of support dimensions and center of mass progression. Understanding how the CNS in able-bodied subjects exerts this control during such a challenging task is a prerequisite to identifying motor disorders in populations with specific impairments of the postural system. It may also provide clinicians with objective measures to assess the efficiency of rehabilitation programs and better target interventions according to individual impairments. The present review thus proposes a state-of-the-art analysis on:(1) the balance control mechanisms in play during gait initiation in able bodied subjects and in the case of some frail populations; and(2) the biomechanical parameters used in the literature to quantify dynamic stability during gait initiation. Balance control mechanisms reviewed in this article included anticipatory postural adjustments, stance leg stiffness, foot placement, lateral ankle strategy, swing foot strike pattern and vertical center of mass braking. Based on this review, the following viewpoints were put forward:(1) dynamic stability during gait initiation may share a principle of homeostatic regulation similar to most physiological variables, where separate mechanisms need to be coordinated to ensure stabilization of vital variables, and consequently; and(2) rehabilitation interventions which focus on separate or isolated components of posture, balance, or gait may limit the effectiveness of current clinical practices. 展开更多
关键词 Balance control Anticipatory POSTURAL ADJUSTMENTS Leg stiffness FOOT placement Lateral ANKLE strategy FOOT STRIKE pattern Vertical center of mass braking Dynamic stability Gait initiation Biomechanics
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A matrix metalloproteinase-responsive hydrogel system controls angiogenic peptide release for repair of cerebral ischemia/reperfusion injury
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作者 Qi Liu Jianye Xie +5 位作者 Runxue Zhou Jin Deng Weihong Nie Shuwei Sun Haiping Wang Chunying Shi 《Neural Regeneration Research》 SCIE CAS 2025年第2期503-517,共15页
Vascular endothelial growth factor and its mimic peptide KLTWQELYQLKYKGI(QK)are widely used as the most potent angiogenic factors for the treatment of multiple ischemic diseases.However,conventional topical drug deliv... Vascular endothelial growth factor and its mimic peptide KLTWQELYQLKYKGI(QK)are widely used as the most potent angiogenic factors for the treatment of multiple ischemic diseases.However,conventional topical drug delivery often results in a burst release of the drug,leading to transient retention(inefficacy)and undesirable diffusion(toxicity)in vivo.Therefore,a drug delivery system that responds to changes in the microenvironment of tissue regeneration and controls vascular endothelial growth factor release is crucial to improve the treatment of ischemic stroke.Matrix metalloproteinase-2(MMP-2)is gradually upregulated after cerebral ischemia.Herein,vascular endothelial growth factor mimic peptide QK was self-assembled with MMP-2-cleaved peptide PLGLAG(TIMP)and customizable peptide amphiphilic(PA)molecules to construct nanofiber hydrogel PA-TIMP-QK.PA-TIMP-QK was found to control the delivery of QK by MMP-2 upregulation after cerebral ischemia/reperfusion and had a similar biological activity with vascular endothelial growth factor in vitro.The results indicated that PA-TIMP-QK promoted neuronal survival,restored local blood circulation,reduced blood-brain barrier permeability,and restored motor function.These findings suggest that the self-assembling nanofiber hydrogel PA-TIMP-QK may provide an intelligent drug delivery system that responds to the microenvironment and promotes regeneration and repair after cerebral ischemia/reperfusion injury. 展开更多
关键词 angiogenesis biomaterial blood-brain barrier cerebral ischemia/reperfusion injury control release drug delivery inflammation QK peptides matrix metalloproteinase-2 NEUROPROTECTION self-assembling nanofiber hydrogel
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Theory of Electromagnetism and Gravity —Modeling Earth as a Rotating Solenoid Coil
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作者 Greg Poole 《Journal of High Energy Physics, Gravitation and Cosmology》 2017年第4期663-692,共30页
Presented in this manuscript are conventional electrical engineering tools to model the earth as a rotating electrical machine. Calculations using known parameters of the earth and measured field data has resulted in ... Presented in this manuscript are conventional electrical engineering tools to model the earth as a rotating electrical machine. Calculations using known parameters of the earth and measured field data has resulted in new understanding of the earth’s electrical system and gyroscopic rotation. The material makeup of the inner earth is better understood based on derived permeability and permittivity constants. The planet has been modeled as simple coils and then as a parallel impedance circuit which has led to fundamental insight into planetary speed control and RLC combination for Schumann Resonance of 7.83 Hz. Torque and Voltage Constants and the inverse Speed Constant are calculated using three methods and all compare favorably with Newton’s Gravitational Constant. A helical resonator is referenced and Schumann’s Resonant ideal frequency is calculated and compared with others idealism. A new theory of gravity based on particle velocity selector at the poles is postulated. Two equations are presented as the needed links between Faraday’s electromagnetism and Newtonian physics. Acceleration and Deceleration of earth is explained as a centripetal governor. A new equation for planetary attraction and the attraction of atomic matter is theorized. Rotation of the earth’s electrical coil is explained in terms of the Richardson effect. Electric power transfer from the sun to the planets is proposed via Flux Transfer Events. The impact of this evolving science of electromagnetic modeling of planets will be magnified as the theory is proven, and found to be useful for future generations of engineers and scientists who seek to discover our world and other planets. 展开更多
关键词 Ampere Biot-Savart CENTRIPETAL Acceleration CENTRIPETAL GOVERNOR Dynamo EARTH Einstein-de Haas Effect Electric Field Electromagnetism Flux Transfer Events GOVERNOR control GRAVITY Gravitational CONSTANT Helical Resonator Lenz Law Lorentz Lightning Magnetic Field Motor CONSTANT Parallel Impedance Planet SPEED control Schumann Resonance Richardson Effect Solenoid SPEED CONSTANT Solar Power System Torque CONSTANT Velocity Selector Voltage CONSTANT
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Active Fault Tolerant Nonsingular Terminal Sliding Mode Control for Electromechanical System Based on Support Vector Machine
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作者 Jian Hu Zhengyin Yang Jianyong Yao 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第3期189-203,共15页
Effective fault diagnosis and fault-tolerant control method for aeronautics electromechanical actuator is concerned in this paper.By borrowing the advantages of model-driven and data-driven methods,a fault tolerant no... Effective fault diagnosis and fault-tolerant control method for aeronautics electromechanical actuator is concerned in this paper.By borrowing the advantages of model-driven and data-driven methods,a fault tolerant nonsingular terminal sliding mode control method based on support vector machine(SVM)is proposed.A SVM is designed to estimate the fault by off-line learning from small sample data with solving convex quadratic programming method and is introduced into a high-gain observer,so as to improve the state estimation and fault detection accuracy when the fault occurs.The state estimation value of the observer is used for state reconfiguration.A novel nonsingular terminal sliding mode surface is designed,and Lyapunov theorem is used to derive a parameter adaptation law and a control law.It is guaranteed that the proposed controller can achieve asymptotical stability which is superior to many advanced fault-tolerant controllers.In addition,the parameter estimation also can help to diagnose the system faults because the faults can be reflected by the parameters variation.Extensive comparative simulation and experimental results illustrate the effectiveness and advancement of the proposed controller compared with several other main-stream controllers. 展开更多
关键词 Aeronautics electromechanical actuator Fault tolerant control Support vector machine State observer Parametric uncertainty
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Characteristics and advantages of adeno-associated virus vector-mediated gene therapy for neurodegenerative diseases 被引量:6
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作者 Yuan Qu Yi Liu +2 位作者 Ahmed Fayyaz Noor Johnathan Tran Rui Li 《Neural Regeneration Research》 SCIE CAS CSCD 2019年第6期931-938,共8页
Common neurodegenerative diseases of the central nervous system are characterized by progressive damage to the function of neurons, even leading to the permanent loss of function. Gene therapy via gene replacement or ... Common neurodegenerative diseases of the central nervous system are characterized by progressive damage to the function of neurons, even leading to the permanent loss of function. Gene therapy via gene replacement or gene correction provides the potential for transformative therapies to delay or possibly stop further progression of the neurodegenerative disease in affected patients. Adeno-associated virus has been the vector of choice in recent clinical trials of therapies for neurodegenerative diseases due to its safety and efficiency in mediating gene transfer to the central nervous system. This review aims to discuss and summarize the progress and clinical applications of adeno-associated virus in neurodegenerative disease in central nervous system. Results from some clinical trials and successful cases of central neurodegenerative diseases deserve further study and exploration. 展开更多
关键词 nerve REGENERATION central nervous system gene therapy NEURODEGENERATIVE DISEASE viral vector ADENO-ASSOCIATED virus Alzheimers DISEASE Parkinsons DISEASE Huntingtons DISEASE amyotrophic lateral SCLEROSIS spinal muscular atrophy neural REGENERATION
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