韩汉语空间方位词使用差异的句法、语义特点——以“?/里”和“?/上”为例

韩汉语都有表示空间概念义的方位词,其中"?/里"和"?/上"是在两种语言中使用频率比较高的空间方位词。这些方位词构成"名词+方位词"结构以后,在很多情况下都能形成语义和形式上的对应关系。但是,韩汉语在表达相关空间概念义时,会出现方位词使用上的差异,主要是"?/里"表示"体范围"和"?/上"表示"平面"义空间方位时,有时可以不用这些空间方位词。"吐"和"里"在表义上的共同特点是都表示"某种范围以内"之义。在句法上,韩国语更倾向于不用方位词"?",如果用了就是为了强调或指明"吐"所表示的"里边"之义;而汉语的情况与此相反,在句法上表示处所的词语一般都得带上方位词"里"。"?"和"上"在表义上的共同特点是都表示"位置在高处或在某一物体的表面"之义。在句法上,所表示的平面类概念如果是"唯一性"的,那么韩国语就不用方位词"?",否则为了避免造成所指不明,需要用上方位词"爿";在汉语中,这些平面类词语都是袁处所的词语,而处所词表示空间时后面需要带上方位词"上"。

河北黄骅方言“V上”结构中“上”的特殊用法

黄骅方言“V上”结构中的“上”,可以表示受事对象逐渐消失义。从句法特点来看,“V上”是一个自主结构,在句中的位置比较灵活,其中涉及到的受事成分以前置于动词为优势。从语义制约来看,该结构中的受事对象是有指的,具有数量特征,数量在动作行为影响下从有变无。从搭配对象来看,与“上”搭配的典型动词主要是现实生活中常用的消耗类动词和去除类动词。

袁枚、曾燠交游考论——兼论《随园诗话补遗》的刊刻过程

袁枚在《随园诗话补遗》卷七中言未曾与曾燠谋面,但考之二人的诗文集,两者多有交往,不但相互唱和赠答,且在诗中明确注明袁枚多次到过曾燠扬州的题襟馆,曾燠也曾去随园拜访袁枚,袁枚扶病相见,二人谈论诗学。现存曾燠所刻《邗上题襟集》中存有袁枚佚诗《题宾谷先生西溪渔隐图》一首。根据曾燠与袁枚交游的诗歌可以推定曾燠的生卒年,纠正包世臣《曾抚部别传》的错误。《随园诗话补遗》的刊刻是一个动态的过程,随得随刻,用原版刻录,只补入,却不修改,于嘉庆二年后定稿,成《随园诗话补遗》十卷。《随园诗话补遗》卷七刊刻时,袁枚未曾见到曾燠,故言“素未识面”。因袁枚有求于曾燠,有了一段名士与官员的密切交往,因为诗歌的媒介,带有了风雅的韵味。

雨天工况动车组受电弓安全状态检测技术研究

受电弓是动车组从接触网获取电源动力的关键部件,其完整性和稳定性对于动车组安全运行至关重要。基于车载视频监控系统采集的图像进行受电弓安全状态检测是目前主流的检测方法,面对雨、雪等恶劣天气,如何更好地处理图像以达到精准检测尤为重要。通过自建受电弓雨天数据集,应用深度学习方法进行图像去雨操作;针对不同类别数据,采用基于生成对抗神经网络(GAN)的数据增强方法,对数据集进行增强;通过对YOLOv5算法进行改造,引入SCCONV结构,改善Backbone区域的特征提取能力,测试模型精度达到98%。该检测流程可在高性能边缘计算模块上达到实时分析效果,为我国铁路车载受电弓视频实时智能分析提供了新的思路。

紫地合剂联合质子泵抑制剂治疗消化性溃疡出血的临床疗效观察

【目的】观察具有收敛止血、清热凉血功效的紫地合剂联合质子泵抑制剂(proton pump inhibitions,PPIs)治疗消化性溃疡出血(peptic ulcer bleeding,PUB)的临床效果。【方法】回顾性收集2019年12月至2023年5月在广州中医药大学第一附属医院急诊病区住院的281例PUB患者,根据治疗方案的不同将其分为对照组143例和观察组138例。对照组患者在一般治疗基础上给予PPIs治疗,观察组在对照组的基础上给予紫地合剂口服治疗,疗程为3 d。观察2组患者治疗前后格拉斯哥-布拉奇福德出血评分(GBS)、血红蛋白量(HGB)、血小板总数(PLT)、血尿素氮(BUN)、血肌酐(Cr)、谷草转氨酶(AST)、谷丙转氨酶(ALT)水平的变化情况,并比较2组患者的平均住院时间和临床疗效。【结果】(1)治疗3 d后,观察组的总有效率为97.10%(134/138),对照组为91.61%(131/143),组间比较(χ^(2)检验),观察组的疗效优于对照组,差异有统计学意义(P<0.05)。(2)治疗后,2组患者的GBS评分均较治疗前降低(P<0.05),且观察组对GBS评分的降低作用优于对照组,差异有统计学意义(P<0.05)。(3)观察组的平均住院时间为(5.81±1.02)d,较对照组的(6.13±1.12)d有所缩短,差异有统计学意义(P<0.05)。(4)治疗后,2组患者外周血HGB、PLT水平较治疗前升高(P<0.05),BUN水平较治疗前降低(P<0.05),且观察组对外周血HGB、PLT水平的升高作用及对BUN水平的降低作用均明显优于对照组,差异均有统计学意义(P<0.05)。(5)治疗过程中,2组患者的外周血AST、ALT、Cr水平均未见升高,差异均无统计学意义(P>0.05)。【结论】紫地合剂联合PPIs治疗PUB效果显著,有助于改善相关血常规和生化指标,缩短住院时间,其疗效优于单纯使用PPIs治疗。

Implications of 1.5 K climate warming on warm-season ozone exposure and atmospheric oxidation capacity in China

Surface ozone(O_(3))poses significant threats to public health,agricultural crops,and plants in natural ecosystems.Global warming is likely to increase future O_(3)mainly by altering atmospheric photochemical reactions and enhancing biogenic volatile organic compound(BVOC)emissions.To assess the impacts of the future 1.5 K climate target on O_(3)concentrations and ecological O_(3)exposure in China,numerical simulations were conducted using the CMAQ(Community Multiscale Air Quality)model during April-October 2018.Ecological O_(3)exposure was estimated using six indices(i.e.,M7,M24,N100,SUM60,W126,and AOT40f).The results show that the temperature rise increases the MDA8 O_(3)(maximum daily eight-hour average O_(3))concentrations by∼3 ppb and the number of O_(3)exceedance days by 10-20 days in the North China Plain(NCP),Yangtze River Delta(YRD),and Sichuan Basin(SCB)regions.All O_(3)exposure indices show substantial increases.M24 and M7 in eastern and southern China will rise by 1-3 ppb and 2-4 ppb,respectively.N100 increases by more than 120 h in the surrounding regions of Beijing.SUM60 increases by greater than 9 ppm h^(−1),W126 increases by greater than 15 ppm h^(−1)in Shaanxi and SCB,and AOT40f increases by 6 ppm h^(−1)in NCP and SCB.The temperature increase also promotes atmospheric oxidation capacity(AOC)levels,with the higher AOC contributed by OH radicals in southern China but by NO_(3)radicals in northern China.The change in the reaction rate caused by the temperature increase has a greater influence on O_(3)exposure and AOC than the change in BVOC emissions.

宁夏固原方言体标记“上[sɑη^(0)]”“下[xa^(0)]”的用法——兼与宝鸡、庆阳的比较

中原官话秦陇片中,方位词“上”“下”可以作为体标记使用。固原原州区方言中,“上”可以用于起始体中,用句式“V+上”表示动作开始并将持续进行;“下”可以用于持续体中,用“处所词+V+下+数量短语+宾语”句式表示动作行为结束后的状态的持续。以固原市原州区方言体标记“上”“下”的用法为参照与周边方言进行比较,可知,原州区与隆德县、甘肃庆阳市同大于异,与陕西宝鸡市异大于同。

Effects of a 4-week internet-delivered mindfulness-based cancer recovery program on anxiety,depression,and mindfulness among patients with breast cancer

Objective:The efficacy of monotherapy in alleviating psychological disorders like anxiety and depression among breast cancer patients is suboptimal,necessitating effective psychosocial interventions.Mindfulness-based interventions have been shown to mitigate anxiety-depression symptoms and encourage beneficial behaviors.The online mindfulness based cancer recovery(MBCR)offers flexibility and guides practice across various settings,facilitating full patient engagement.This study amis to analyze the impact of a 4-week internet-delivered mindfulness-based cancer recovery program on anxiety,depression,and mindfulness among Chinese patients with breast cancer,and to evaluate the degree of satisfaction breast cancer patients experienced after participating in this program.Methods:This study utilized a two-armed,parallel,randomized controlled trial design.A total of 103 patients with breast cancer from June 2020 to January 2021 in the ward of Breast and Thyroid Surgery of a tertiary hospital in Changsha,Hunan Province were selected and randomly assigned to an intervention group(n=51)and a control group(n=52).The intervention group participated in an internet-delivered mindfulness-based cancer recovery program,which was delivered once a week for 4 weeks.Meanwhile,the control group received weekly group health education for 4 weeks.The outcomes of hospital anxiety and depression scale and mindfulness Attention Awareness Scale were evaluated at 3 distinct time points:Baseline(T1),postintervention(T2),and 1-month follow-up(T3).The satisfaction questionnaire of 4-week mindful cancer rehabilitation training program was used at T2 to evaluate patients’satisfaction with the intervention program.Generalized estimation equations were used to assess differences in anxiety,depression and mindfulness levels between groups before and after the intervention.Results:There were no statistically significant differences in demographic data and outcome index scores between the 2 groups at T1(all P>0.05),indicating that the 2 groups were comparable.The generalized estimating equation analyses showed that the intervention group had significantly better improvement in outcomes compared to the control group,particularly for anxiety(T2β=−1.30,95%CI−1.87 to−0.72;T3β=−2.78,95%CI−3.51 to−2.05)and depression(T2β=−1.92,95%CI−2.78 to−1.06;T3β=−2.96,95%CI−4.05 to−1.87;all P<0.001).Moreover,the mindfulness score in the intervention group was significantly higher than that in the control group at T2(β=3.23,95%CI 0.73 to 5.72)and T3(β=8.06,95%CI 4.37 to 11.75;both P<0.05).In addition,patients in the intervention group were satisfied with the 4-week mindfulness-based cancer recovery intervention and teaching/learning activities used to implement the program.Conclusion:In patients with breast cancer,the 4-week internet-delivered mindfulness based cancer recovery program,as a low-threshold,short-term mental health intervention,has a positive effect on reducing anxiety and depression and improving mindfulness levels.This program holds great promise as a tool for clinical nursing practice,given the high satisfaction and applicability.

CDK8 Promotes Cell Proliferation, Migration and Invasion in Esophageal Squamous Cell Carcinoma Through JAK/ STAT3/EMT Pathway

Objective To investigate the expression of cyclin-dependent kinase 8(CDK8)in esophageal squamous cell carcinoma(ESCC)and its effect on ESCC cells,and to explore its potential molecular mechanism.Methods The expression level of CDK8 mRNA was analyzed using UALCAN database,and then the expression level of CDK8 protein in tumor tissues of ESCC patients was detected by immunohistochemistry(IHC).Esophageal cancer cell lines Kyse-30 and Kyse-150 were stably transfected with lentivirus to achieve knockdown and overexpression of CDK8.EdU proliferation assay,cell colony formation assay,cell cycle assay,cell scratch assay and invasion assay were used to explore the effect of CDK8 protein expression level on the phenotype of ESCC cells.Subsequently,the effect of CDK8 on the growth of esophageal cancer xenografts in vitro was observed by subcutaneous tumor formation assay in mice.Finally,the expression of proliferation and metastasis related proteins was detected by Western blot.Results CDK8 showed high transcription and protein expression levels in ESCC tissues compared with normal esophageal tissues.Knockdown of CDK8 expression significantly inhibited the proliferation,migration and invasion of ESCC cells.In addition,inhibition of CDK8 expression significantly affected the JAK2/STAT3 pathway and the expression of E-cadherin/N-cadherin,while overexpression of CDK8 reversed these effects.Inhibition of STAT3 pathway reversed the promoting effect of CDK8 overexpression on ESCC cell phenotype.Conclusion CDK8 is a cancer-promoting factor of ESCC,which mediates the phosphorylation of JAK2/STAT3 and epithelial-mesenchymal transition(EMT).

Recovery after ischemic stroke:Effects of FuekFone home-based program on upper limb and cognitive function

Objectives:This study aimed to explore the effects of the“FuekFone(F.F.)home-based program”on the upper limb and cognitive function of ischemic stroke patients after discharge.Methods:A single group pre-and post-test design was conducted.A total of 40 patients with recovery after ischemic stroke were recruited from two university hospitals in Thailand.The study was conducted between June 2022 and January 2023.Participants underwent a six-week“F.F.home-based program,”which combined an upper limb and cognitive function rehabilitation device with Android games,including stationary barrel,adventure walk,adventure stroll,sliding barrel,sauce squeeze,and cut objects.Each game has different difficulty levels.Patients can perform corresponding exercises through the games according to their conditions under the guidance of medical staff.The patients played for 24 min per time,4 min each game,three days a week.The second week,let the patients play games for 30 min per time,5 min each game,3 days a week.Then,in the 3e6 weeks,let the patients play games for 1 h per time,10 min each game,5 days a week.At the pre-and post-intervention,the Thai version of the National Institutes of Health Stroke Scale(NIHSS),the Motor Assessment Scale,and the Montreal Cognitive Assessment(MoCA score)were administered to patients at discharge and at 2,4,and 6 weeksafter discharge,and the results were compared.Results:All participants completed this program.Participants had statistically improved upper limb function(upper arm function score,hand movements score,advanced hand activities score,total Motor Assessment Scale score)and MoCA score at 2,4,and 6 weeks after discharge(P<0.001).In the comparison of upper limb function and cognitive function at each of the study times,we found statistically improved upper limb function(upper arm function score,hand movements score,advanced hand activities score,total Motor Assessment Scale score)and MoCA score at 4,and 6 weeks after discharge when compared to after discharge and 2 weeks after discharge,respectively(P<0.05).Conclusions:Continuing care of patients post-stroke after discharge from hospital,such as F.F.homebased program should be applied at home to enhance upper limb and cognitive function.

Design and evaluation of UHPP steel bridge deck pavement for high-temperature and rainy regions

To enhance the serviceability of steel bridge deck pavement(SBDP)in high-temperature and rainy regions,a concept of rigid bottom and flexible top was summarized using engineering practices,which led to the proposal of a three-layer ultra-high-performance pavement(UHPP).The high-temperature rutting resistance and wet-weather skid resistance of UHPP were evaluated through composite structure tests.The internal temperature distribution within the pavement under typical high-temperature conditions was analyzed using a temperature field model.Additionally,a temperature-stress coupling model was employed to investigate the key load positions and stress response characteristics of the UHPP.The results indicate that compared with the traditional guss asphalt+stone mastic asphalt structure,the dynamic stability of the UHPP composite structure can be improved by up to 20.4%.Even under cyclic loading,UHPP still exhibits superior surface skid resistance compared to two traditional SBDPs.The thickness composition of UHPP significantly impacts its rutting resistance and skid resistance.UHPP exhibits relatively low tensile stress but higher shear stress levels,with the highest shear stress occurring between the UHPP and the steel plate.This suggests that the potential risk of damage for UHPP primarily lies within the interlayer of the pavement.Based on engineering examples,introducing interlayer gravel and optimizing the amount of bonding layer are advised to ensure that UHPP possesses sufficient interlayer shear resistance.

Effect and mechanism of on-chip electrostatic discharge protection circuit under fast rising time electromagnetic pulse

The electrostatic discharge(ESD)protection circuit widely exists in the input and output ports of CMOS digital circuits,and fast rising time electromagnetic pulse(FREMP)coupled into the device not only interacts with the CMOS circuit,but also acts on the protection circuit.This paper establishes a model of on-chip CMOS electrostatic discharge protection circuit and selects square pulse as the FREMP signals.Based on multiple physical parameter models,it depicts the distribution of the lattice temperature,current density,and electric field intensity inside the device.At the same time,this paper explores the changes of the internal devices in the circuit under the injection of fast rising time electromagnetic pulse and describes the relationship between the damage amplitude threshold and the pulse width.The results show that the ESD protection circuit has potential damage risk,and the injection of FREMP leads to irreversible heat loss inside the circuit.In addition,pulse signals with different attributes will change the damage threshold of the circuit.These results provide an important reference for further evaluation of the influence of electromagnetic environment on the chip,which is helpful to carry out the reliability enhancement research of ESD protection circuit.

Improved Berry-Esseen Bound for Rademacher Sum

Let X=Σ_(i=1)^(n)a_(i)ξ_(i)be a Rademacher sum with Var(X)=1 and Z be a standard normal random variable.This paper concerns the upper bound of|P(X≤x)−P(Z≤x)|for any x∈R.Using the symmetric properties and R software,this paper gets the following improved Berry-Esseen type bound under some conditions,|P(X≤x)−P(Z≤x)|≤P(Z∈(0,a1)),∀x∈R,which is one of the modified conjecture proposed by Nathan K.and Ohad K.

某梯级电站巨型水轮发电机总体设计研究

某梯级电站所处河流段水力资源丰富、落差巨大,地质结构复杂,土建成本高。该梯级电站天然属性决定了电站装机必然是高转速、大容量水轮发电机型。水轮发电机总体设计方案和单机容量、转速、电压相关,也受制于机组飞逸转速、水轮机轴向推力、径向不平衡力。总结某梯级电站水轮发电机电磁、通风、绝缘、轴承、刚强度、机组轴系稳定等各方面研究成果,并针对某梯级电站具体特点,对各电站水轮发电机总体设计方案进行论证,找出影响设计方案可行的关键因素,为电站总体规划设计提供支持。

Effect of acetyl L-carnitine on human retinal pigment epithelium-19 cells in hypoxic conditions

AIM:To investigate the effect of acetyl-L-carnitine(ALCAR)on cell viability,morphological integrity,and vascular endothelial growth factor(VEGF)expression in human retinal pigment epithelium(ARPE-19)cells using a hypoxic model.METHODS:In the first set of experiments,the optimal CoCl_(2) dose was determined by exposing ARPE-19 cell cultures to different concentrations.To evaluate the effect of ALCAR on cell viability,five groups of ARPE-19 cell culture were established that included a control group,a sham group(200μM CoCl_(2)),and groups that received 1,10 and 100 mM doses of ALCAR combined with 200μM CoCl_(2),respectively.The cell viability was measured by MTT assay.The morphological characteristics of cells were observed by an inverted phase contrast microscope.The levels of VEGF and HIF-1α secretion by ARPE-19 cells were detected by enzyme linked immunosorbent assay(ELISA)assay.RESULTS:ARPE-19 cells were exposed to different doses of CoCl_(2) in order to create a hypoxia model.Nevertheless,when exposed to a concentration of 200μM CoCl_(2),a notable decrease in viability to 83% was noted.ALCAR was found to increase the cell viability at 1 mM and 10 mM concentrations,while the highest concentration(100 mM)did not have an added effect.The cell viability was found to be significantly higher in the groups treated with a concentration of 1 mM and 10 mM ALCAR compared to the Sham group(P=0.041,P=0.019,respectively).The cell viability and morphology remained unaffected by the greatest dose of ALCAR(100 mM).The administration of 10 mM ALCAR demonstrated a statistically significant reduction in the levels of VEGF and HIF-1α compared with the Sham group(P=0.013,P=0.033,respectively).CONCLUSION:The findings from the current study indicate that ALCAR could represent a viable therapeutic option with the potential to open up novel treatment pathways for retinal diseases,particular relevance for age-related macular degeneration(AMD).However,to fully elucidate ALCAR’s application potential in retinal diseases,additional investigation is necessary to clearly define the exact mechanisms involved.

Asymptotic Dynamics of a Single-species Model with Resource-dependent Dispersal in One Dimension

In this paper,we study the asymptotic dynamics of a single-species model with resource-dependent dispersal in one dimension.To overcome the analytical difficulties brought by the resource-dependent dispersal,we use the idea of changing variables to transform the model into a uniform dispersal one.Then the existence and uniqueness of positive stationary solution to the model can be verified by the squeezing argument,where the solution plays a crucial role in later analyses.Moreover,the asymptotic behavior of solutions to the model is obtained by the upper-lower solutions method.The result indicates that the solutions of the model converge to the corresponding positive stationary solution locally uniformly in one dimension as time goes to infinity.

《脉书·上经》重要语句三题

本文通过对于《脉书·上经》中三处重要语句:“人有九窍、五藏、十二节皆鼂于气”“金之通天气为天府”“臂之大阴为脉口”的解读,以求管窥早期经脉在独立循行,不相连贯之时,诊脉口的原理。该三句为全篇纲领性的语句,对于我们理解早期经脉医学的内涵,探索其理论的源流演变具有重要的价值和意义。

《脉书·上经》中四时疾病系统探析

天回镇出土医简《脉书·上经》中记载了五脏通天,分别通于四时与中州。本文通过对四时思想起源的探讨,以及出土文献与传世文献的对读比较,认为四时思想在医学中的关切首先在于疾病,这种四时疾病系统在《脉书·上经》中与五藏相结合,旨在说明四时五脏疾病的部位与诊治原则。

Towing characteristics of large-scale composite bucket foundation for offshore wind turbines

In order to study the towing dynamic properties of the large-scale composite bucket foundation the hydrodynamic software MOSES is used to simulate the dynamic motion of the foundation towed to the construction site.The MOSES model with the prototype size is established as the water draft of 5 and 6 m under the environmental conditions on site.The related factors such as towing force displacement towing accelerations in six degrees of freedom of the bucket foundation and air pressures inside the bucket are analyzed in detail.In addition the towing point and wave conditions are set as the critical factors to simulate the limit conditions of the stable dynamic characteristics.The results show that the large-scale composite bucket foundation with reasonable subdivisions inside the bucket has the satisfying floating stability.During the towing process the air pressures inside the bucket obviously change little and it is found that the towing point at the waterline is the most optimal choice.The characteristics of the foundation with the self-floating towing technique are competitive for saving lots of cost with few of the expensive types of equipment required during the towing transportation.

雪上一枝蒿速效止痛搽剂的抗炎镇痛作用研究

目的研究雪上一枝蒿速效止痛搽剂的抗炎镇痛作用。方法通过小鼠耳廓肿胀,腹腔毛细血管通透性实验观察其抗炎作用;通过热板法和醋酸扭体法观察其镇痛作用。结果雪上一枝蒿速效止痛搽剂能显著抑制二甲苯所致小鼠耳廓肿胀,醋酸所致小鼠毛细血管通透性增高;提高热板法疼痛模型小鼠痛阈,抑制醋酸所致小鼠扭体痛反应。结论雪上一枝蒿速效止痛搽剂具有显著的抗炎、镇痛作用。