Hemangioblastomas are benign vascular tumors of the brain. These are rare tumors, usually located in the cerebellum and most often affecting young adults. The aim was to study the value of CT in the management of hema...Hemangioblastomas are benign vascular tumors of the brain. These are rare tumors, usually located in the cerebellum and most often affecting young adults. The aim was to study the value of CT in the management of hemangioblastoma through observation. We report the case of a 38-year-old patient referred to the radiology and Medical Imaging Department of the Marie Curie Medical Clinic in Bamako, Mali, for an orbito-cerebral CT scan in a context of bilateral eyelid edema. The examination was performed using multi-slice computed tomography (16 slices) with reconstruction in the 3 planes of space without and with the injection of an iodinated contrast agent. The CT scan was crucial in making the diagnosis of hemangioblastoma incidentally, which allowed for adequate management. The patient was operated on, and the radiological outcome was favorable, without significant cystic formation, after postoperative control and clinical signs were resolved. CT can be an interesting alternative in countries like ours despite MRI being the examination of choice in hemangioblastomas.展开更多
HEMANGIOBLASTOMA(HB),a kind of benign tumor with uncertain histogenesis,is Characterized by the presence of stromal cells(SCs)and a rich vascular component.1 It occurs sporadi cally,
We performed contrast-enhanced T2 fluid-attenuated inversion recovery(T2-FLAIR)and dynamic contrast enhanced MRI to illustrate the imaging characteristics of one case of hemangioblastoma.T2-FLAIR showed a large cyst l...We performed contrast-enhanced T2 fluid-attenuated inversion recovery(T2-FLAIR)and dynamic contrast enhanced MRI to illustrate the imaging characteristics of one case of hemangioblastoma.T2-FLAIR showed a large cyst located in the right cerebellum with mural nodule.The intensely enhancing cyst wall was observed on enhanced T2-FLAIR images acquired from 5.6 to 23 minutes after contrast administration,and quantitative dynamic contrast enhanced-MRI demonstrated that both the cyst wall and mural nodule presented high Ktrans,Kep and Ve values compared with the contralateral normal cerebellar tissues.The cyst showed gradual enhancement and reached the highest signal intensity at 67 minutes after contrast administration on enhanced T2-FLAIR images.In conclusion,early enhancement of cyst wall on T2-FLAIR might be the characteristic imaging findings for cystic hemangioblastoma,which may assist in the diagnosis of hemangioblastoma preoperatively.展开更多
BACKGROUND Hemangioblastoma(HB)is a rare tumor,comprising about 2%of all intracranial tumors.Although it is a benign tumor,due to the abundant blood supply and its close relationship with adjacent cerebral blood vesse...BACKGROUND Hemangioblastoma(HB)is a rare tumor,comprising about 2%of all intracranial tumors.Although it is a benign tumor,due to the abundant blood supply and its close relationship with adjacent cerebral blood vessels,surgical resection is difficult and may cause complications such as bleeding.If HB can be correctly diagnosed before surgery,complications can be avoided by methods such as vascular embolism before surgery.CASE SUMMARY A 51-year-old male patient was admitted to our hospital because of blurred vision in his left eye for 2 years.Ophthalmological examination revealed oculus dexter vision acuity of 1.0 and oculus sinister vision acuity of 0.6.His left vision had tubular visual field,while his right vision had a partial defect.Computed tomography and magnetic resonance imaging showed a mass lesion at the left anterior base of the skull,which could have been a meningioma.During the operation,the tumor was found to be located at the entrance of the left optic nerve tube,closely adhering to the left optic nerve and the blood supply was extremely abundant.The tumor was carefully separated and diagnosed as HB postoperatively after pathological examination.CONCLUSION A rare HB at the anterior skull base could be distinguished by its imaging features,which is essential to the surgical procedures.展开更多
BACKGROUND Hepatic hemangioblastoma is an extremely rare disease;only three cases have been reported in the literature,and its magnetic resonance imaging(MRI)findings are unreported.CASE SUMMARY We report a case of in...BACKGROUND Hepatic hemangioblastoma is an extremely rare disease;only three cases have been reported in the literature,and its magnetic resonance imaging(MRI)findings are unreported.CASE SUMMARY We report a case of incidental hepatic hemangioblastoma.The patient had no history of von Hippel-Lindau disease or associated clinical signs.Computed tomography and MRI showed a large tumor occupying almost half of the right side of the liver with expansive growth,well-defined borders,heterogeneous mildly progressive enhancement,and visibly enlarged blood supply vessels.Flow voids were observed on T2-weighted imaging.Both diffusion-weighted imaging(DWI)and apparent diffusion coefficient(ADC)map findings of the mass were predominantly inhomogeneous.Postoperative pathology indicated a diagnosis of hemangioblastoma.CONCLUSION Enlarged peripheral blood-supplying vessels and progressive enhancement seem to be typical imaging features of hepatic hemangioblastoma.However,a solid significantly enhanced mass with a low signal on DWI and a high signal on ADC may also be helpful for the diagnosis of hepatic hemangioblastoma.展开更多
Objective To elucidate the diagnosis and surgical treatment of the posterior fossa solid hemangio^blastomas (PFSHs) Methods The data from 22 patients with PFSHs verified by surgery and pathology were analyzed retro...Objective To elucidate the diagnosis and surgical treatment of the posterior fossa solid hemangio^blastomas (PFSHs) Methods The data from 22 patients with PFSHs verified by surgery and pathology were analyzed retrospectively and a review of relevant literature was conducted Results The preoperative definitive diagnosis rate was 13/22 Total tumor removal was achieved in 20 patients Two of the 22 patients died after surgery, one of brain stem injury and the other from an intracranial hemorrhage Twenty patients were followed up for 2 months to 8 yeas (average, 2 years) Karnofsky scale was 80 in 15 patients, 60-70 in 1 patient and not measured in 4 patients who died during follow up The causes of death were pneumonia (2 patients) and purulent meningitis (2) Conclusion MRI and DSA (digital subtraction angiography) are major preoperative diagnostic modalities for PFSH, but PFSH remains a challenging benign neoplasm Special microsurgical techniques and improved operative manipulation can improve surgical efficacy展开更多
OBJECTIVE: To investigate the diagnosis and surgical techniques of intramedullary hemangioblastoma of the cervical spinal cord. METHODS: MR imaging and the methods and results of surgery were analyzed in 21 patients. ...OBJECTIVE: To investigate the diagnosis and surgical techniques of intramedullary hemangioblastoma of the cervical spinal cord. METHODS: MR imaging and the methods and results of surgery were analyzed in 21 patients. RESULTS: The tumors were divided into three types on MR imaging. Syringeal type, where the tumor varied in size and was accompanied by syringobulbia and syringomyelia; Cystic type, where the tumor presented as a cyst with a small mural node; and Solid type, where the tumor was revealed as a huge solid mass. All tumors were totally removed and diagnosis was confirmed by histological study. Post-operative neurological status was improved in 20 patients and aggravated in 1. CONCLUSIONS: The localization and the nature diagnosis of the tumor can be made by cervical MR imaging. Operative methods vary with tumor types. It is the most important that the tumor is dissected along the right interface and removed after devascularization.展开更多
Thirteen cases of intramedullary hemangioblastoma of the spinal cord were studied radiologically, especially with magnetic resonance imaging (MRI). Microsurgery was used to remove the tumors in all cases. Signs and sy...Thirteen cases of intramedullary hemangioblastoma of the spinal cord were studied radiologically, especially with magnetic resonance imaging (MRI). Microsurgery was used to remove the tumors in all cases. Signs and symptoms were improved in 84.6% of the cases after operation. The diagnosis and microsurgical techniques for excision of intramedullary hemangioblastoma of the spinal cord are discussed. This dis-ease should be differentiated from hydromyelia, intramedullary ependymoma, and vascular malformation of the spinal cord. Total removal of the tumor is recommened.展开更多
Objectives: To discuss the bleeding mechanisms after removing a medulla oblongata hemangioblastoma. Methods: A 42-year-old male patient was diagnosed with a medulla oblongata hemangioblastoma. Preoperative cranial mag...Objectives: To discuss the bleeding mechanisms after removing a medulla oblongata hemangioblastoma. Methods: A 42-year-old male patient was diagnosed with a medulla oblongata hemangioblastoma. Preoperative cranial magnetic resonance imaging, computed tomography angiography and post-surgery computed tomography were completed during clinical procedure. We also reviewed the related literatures. Results: The preoperative computed tomography angiography did not demonstrate any intracranial aneurysm. But, the patient had a fatal subarachnoid hemorrhage with ventricular hemorrhage 4 hours after surgery following the post-surgery computed tomography. Conclusions: Subarachnoid hemorrhage after surgery of the medulla oblongata hemangioblastoma is very rare. Delayed postoperative hemorrhage seems the most reasonable explanation of Subarachnoid hemorrhage in our case.展开更多
文摘Hemangioblastomas are benign vascular tumors of the brain. These are rare tumors, usually located in the cerebellum and most often affecting young adults. The aim was to study the value of CT in the management of hemangioblastoma through observation. We report the case of a 38-year-old patient referred to the radiology and Medical Imaging Department of the Marie Curie Medical Clinic in Bamako, Mali, for an orbito-cerebral CT scan in a context of bilateral eyelid edema. The examination was performed using multi-slice computed tomography (16 slices) with reconstruction in the 3 planes of space without and with the injection of an iodinated contrast agent. The CT scan was crucial in making the diagnosis of hemangioblastoma incidentally, which allowed for adequate management. The patient was operated on, and the radiological outcome was favorable, without significant cystic formation, after postoperative control and clinical signs were resolved. CT can be an interesting alternative in countries like ours despite MRI being the examination of choice in hemangioblastomas.
基金Supported by Wannan Medical College Key Research Projects(WK2016Z08)
文摘HEMANGIOBLASTOMA(HB),a kind of benign tumor with uncertain histogenesis,is Characterized by the presence of stromal cells(SCs)and a rich vascular component.1 It occurs sporadi cally,
文摘We performed contrast-enhanced T2 fluid-attenuated inversion recovery(T2-FLAIR)and dynamic contrast enhanced MRI to illustrate the imaging characteristics of one case of hemangioblastoma.T2-FLAIR showed a large cyst located in the right cerebellum with mural nodule.The intensely enhancing cyst wall was observed on enhanced T2-FLAIR images acquired from 5.6 to 23 minutes after contrast administration,and quantitative dynamic contrast enhanced-MRI demonstrated that both the cyst wall and mural nodule presented high Ktrans,Kep and Ve values compared with the contralateral normal cerebellar tissues.The cyst showed gradual enhancement and reached the highest signal intensity at 67 minutes after contrast administration on enhanced T2-FLAIR images.In conclusion,early enhancement of cyst wall on T2-FLAIR might be the characteristic imaging findings for cystic hemangioblastoma,which may assist in the diagnosis of hemangioblastoma preoperatively.
基金Supported by Shanghai Sailing Program,No.22YF1405000Greater Bay Area Institute of Precision Medicine(Guangzhou),No.KCH2310094。
文摘BACKGROUND Hemangioblastoma(HB)is a rare tumor,comprising about 2%of all intracranial tumors.Although it is a benign tumor,due to the abundant blood supply and its close relationship with adjacent cerebral blood vessels,surgical resection is difficult and may cause complications such as bleeding.If HB can be correctly diagnosed before surgery,complications can be avoided by methods such as vascular embolism before surgery.CASE SUMMARY A 51-year-old male patient was admitted to our hospital because of blurred vision in his left eye for 2 years.Ophthalmological examination revealed oculus dexter vision acuity of 1.0 and oculus sinister vision acuity of 0.6.His left vision had tubular visual field,while his right vision had a partial defect.Computed tomography and magnetic resonance imaging showed a mass lesion at the left anterior base of the skull,which could have been a meningioma.During the operation,the tumor was found to be located at the entrance of the left optic nerve tube,closely adhering to the left optic nerve and the blood supply was extremely abundant.The tumor was carefully separated and diagnosed as HB postoperatively after pathological examination.CONCLUSION A rare HB at the anterior skull base could be distinguished by its imaging features,which is essential to the surgical procedures.
文摘BACKGROUND Hepatic hemangioblastoma is an extremely rare disease;only three cases have been reported in the literature,and its magnetic resonance imaging(MRI)findings are unreported.CASE SUMMARY We report a case of incidental hepatic hemangioblastoma.The patient had no history of von Hippel-Lindau disease or associated clinical signs.Computed tomography and MRI showed a large tumor occupying almost half of the right side of the liver with expansive growth,well-defined borders,heterogeneous mildly progressive enhancement,and visibly enlarged blood supply vessels.Flow voids were observed on T2-weighted imaging.Both diffusion-weighted imaging(DWI)and apparent diffusion coefficient(ADC)map findings of the mass were predominantly inhomogeneous.Postoperative pathology indicated a diagnosis of hemangioblastoma.CONCLUSION Enlarged peripheral blood-supplying vessels and progressive enhancement seem to be typical imaging features of hepatic hemangioblastoma.However,a solid significantly enhanced mass with a low signal on DWI and a high signal on ADC may also be helpful for the diagnosis of hepatic hemangioblastoma.
文摘Objective To elucidate the diagnosis and surgical treatment of the posterior fossa solid hemangio^blastomas (PFSHs) Methods The data from 22 patients with PFSHs verified by surgery and pathology were analyzed retrospectively and a review of relevant literature was conducted Results The preoperative definitive diagnosis rate was 13/22 Total tumor removal was achieved in 20 patients Two of the 22 patients died after surgery, one of brain stem injury and the other from an intracranial hemorrhage Twenty patients were followed up for 2 months to 8 yeas (average, 2 years) Karnofsky scale was 80 in 15 patients, 60-70 in 1 patient and not measured in 4 patients who died during follow up The causes of death were pneumonia (2 patients) and purulent meningitis (2) Conclusion MRI and DSA (digital subtraction angiography) are major preoperative diagnostic modalities for PFSH, but PFSH remains a challenging benign neoplasm Special microsurgical techniques and improved operative manipulation can improve surgical efficacy
文摘OBJECTIVE: To investigate the diagnosis and surgical techniques of intramedullary hemangioblastoma of the cervical spinal cord. METHODS: MR imaging and the methods and results of surgery were analyzed in 21 patients. RESULTS: The tumors were divided into three types on MR imaging. Syringeal type, where the tumor varied in size and was accompanied by syringobulbia and syringomyelia; Cystic type, where the tumor presented as a cyst with a small mural node; and Solid type, where the tumor was revealed as a huge solid mass. All tumors were totally removed and diagnosis was confirmed by histological study. Post-operative neurological status was improved in 20 patients and aggravated in 1. CONCLUSIONS: The localization and the nature diagnosis of the tumor can be made by cervical MR imaging. Operative methods vary with tumor types. It is the most important that the tumor is dissected along the right interface and removed after devascularization.
文摘Thirteen cases of intramedullary hemangioblastoma of the spinal cord were studied radiologically, especially with magnetic resonance imaging (MRI). Microsurgery was used to remove the tumors in all cases. Signs and symptoms were improved in 84.6% of the cases after operation. The diagnosis and microsurgical techniques for excision of intramedullary hemangioblastoma of the spinal cord are discussed. This dis-ease should be differentiated from hydromyelia, intramedullary ependymoma, and vascular malformation of the spinal cord. Total removal of the tumor is recommened.
基金the National Natural Science Foundation of China:Emergency Management Project
文摘Objectives: To discuss the bleeding mechanisms after removing a medulla oblongata hemangioblastoma. Methods: A 42-year-old male patient was diagnosed with a medulla oblongata hemangioblastoma. Preoperative cranial magnetic resonance imaging, computed tomography angiography and post-surgery computed tomography were completed during clinical procedure. We also reviewed the related literatures. Results: The preoperative computed tomography angiography did not demonstrate any intracranial aneurysm. But, the patient had a fatal subarachnoid hemorrhage with ventricular hemorrhage 4 hours after surgery following the post-surgery computed tomography. Conclusions: Subarachnoid hemorrhage after surgery of the medulla oblongata hemangioblastoma is very rare. Delayed postoperative hemorrhage seems the most reasonable explanation of Subarachnoid hemorrhage in our case.